gene	symbol	name	description
FBgn0000008	a	arc	arc (a) encodes a protein involved in eye development. [Date last reviewed: 2019-09-12]
FBgn0000017	Abl	Abl tyrosine kinase	Abl tyrosine kinase (Abl) encodes a non-receptor tyrosine kinase best known for its ortholog's role in human leukemia. It phosphorylates cell adhesion and cytoskeletal proteins and acts as a scaffold in a signaling complex to regulate both epithelial and nervous system morphogenesis. [Date last reviewed: 2019-03-07]
FBgn0000018	abo	abnormal oocyte	abnormal oocyte (abo) encodes a negative regulator of histone transcription genes by its binding to their regulatory regions. abo mutations cause a maternal-effect lethality that can be rescued by specific regions of heterochromatin during early embryogenesis. [Date last reviewed: 2018-09-06]
FBgn0000032	Acph-1	Acid phosphatase 1	NA
FBgn0000042	Act5C	Actin 5C	NA
FBgn0000043	Act42A	Actin 42A	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0000052	Pfas	Phosphoribosylformylglycinamidine synthase	Phosphoribosylformylglycinamidine synthase (Pfas) encodes a phosphoribosylformylglycinamidine synthase, which is an essential enzyme in the pathway for de novo synthesis of the purine nucleotide inosine monophosphate (IMP). IMP is the precursor for purine nucleotides required for nucleic acids, energy transfer, cell signaling, and coenzymes. [Date last reviewed: 2019-03-14]
FBgn0000053	Gart	GART trifunctional enzyme	GART trifunctional enzyme (Gart) encodes a multifunctional enzyme that exhibits phosphoribosylamine-glycine ligase, phosphoribosylformylglycinamidine cyclo-ligase and phosphoribosylglycinamide formyltransferase activities. [Date last reviewed: 2019-09-12]
FBgn0000057	adp	adipose	adipose (adp) encodes a protein involved in lipid metabolism and fat storage. [Date last reviewed: 2019-09-12]
FBgn0000063	Mps1	Monopolar spindle 1	Monopolar spindle 1 (Mps1) encodes a conserved protein kinase that is associated with kinetochores and is required for the mitotic and meiotic spindle assembly checkpoints. [Date last reviewed: 2018-09-06]
FBgn0000064	Ald1	Aldolase 1	NA
FBgn0000071	Ama	Amalgam	NA
FBgn0000077	amx	almondex	NA
FBgn0000079	Amy-p	Amylase proximal	Amylase proximal (Amy-p) encodes one of three amylases encoded in the Drosophila genome. It is a digestive enzyme required for the hydrolysis of dietary starch. [Date last reviewed: 2019-03-07]
FBgn0000083	AnxB9	Annexin B9	NA
FBgn0000084	AnxB10	Annexin B10	Annexin B10 (AnxB10) encodes a calcium-dependent phospholipid binding protein. [Date last reviewed: 2019-07-11]
FBgn0000097	aop	anterior open	anterior open (aop) encodes a transcriptional repressor of the ETS family. It acts downstream of receptor tyrosine kinase signaling to regulate cell fate transitions critical to the development of many tissues including the nervous system, heart, trachea and eye. [Date last reviewed: 2019-03-07]
FBgn0000100	RpLP0	Ribosomal protein LP0	NA
FBgn0000108	Appl	beta amyloid protein precursor-like	NA
FBgn0000109	Aprt	Adenine phosphoribosyltransferase	NA
FBgn0000115	Arl1	ADP ribosylation factor-like 1	NA
FBgn0000116	Argk	Arginine kinase	NA
FBgn0000117	arm	armadillo	armadillo (arm) encodes the Drosophila homolog of beta-catenin. It plays separable roles in cell adhesion and Wingless signaling. It links classic cadherin cell adhesion receptors to alpha-catenin and the actin cytoskeleton, and it acts as the key regulated effector of Wingless signaling, working with TCF/LEF proteins as a transcriptional co-activator. [Date last reviewed: 2019-03-07]
FBgn0000119	arr	arrow	arrow (arr) encodes a type I trans-membrane protein and functions as an obligate co-receptor with the product of fz for the ligand encoded by wg in the canonical Wnt signaling pathway. The product of arr is involved in developmental patterning, cell survival and growth regulation. [Date last reviewed: 2019-03-07]
FBgn0000139	ash2	absent, small, or homeotic discs 2	absent, small, or homeotic discs 2 (ash2) encodes a component of the histone methyltransferase complex that specifically methylates lysine 4 of histone H3 and a member of the trithorax family. ash2 mutants show homeotic transformations and a variety of pattern-formation defects. [Date last reviewed: 2019-03-07]
FBgn0000140	asp	abnormal spindle	NA
FBgn0000146	aub	aubergine	NA
FBgn0000147	aurA	aurora A	aurora A (aurA) encodes a protein kinase required for proper neuroblast self-renewal by regulating assymmetric protein localization. It contributes to spindle orientation, centrosome separation and pole cell formation. [Date last reviewed: 2019-06-13]
FBgn0000150	awd	abnormal wing discs	abnormal wing discs (awd) encodes a nucleotide diphosphate kinase that regulates with the product of shi the endocytosis of different surface proteins (e.g. those encoded by N, btl, Pvr, and shg). During development, it regulates morphogenesis of trachea, follicular epithelium, and imaginal discs and contributes to neurotransmission and border cell migration. [Date last reviewed: 2019-03-07]
FBgn0000152	Axs	Abnormal X segregation	Abnormal X segregation (Axs) encodes a member of transmembrane proteins with calcium-activated chloride activity. Axs product localizes to a membranous sheath that surrounds the oocyte meiosis I spindle. A dominant mutation in Axs results in barrel-shaped meiosis I spindles, cell cycle defects, and missegregation of nonexchange chromosomes in oocytes. [Date last reviewed: 2018-09-06]
FBgn0000163	baz	bazooka	bazooka (baz) encodes a scaffold protein that forms a complex with the products of par-6 and aPKC and with other cortical, cytoskeletal and regulatory proteins. It functions in cell polarization pathways in epithelial, neuronal and other cell types. [Date last reviewed: 2019-03-07]
FBgn0000173	ben	bendless	bendless (ben) encodes an E2 ubiquitin-conjugating enzyme. It plays essential roles in multiple processes such as synaptic growth and maturation, axon guidance, innate immunity, genomic integrity, tumor growth, cell invasion, apoptosis, long-term memory and escape response. [Date last reviewed: 2019-03-07]
FBgn0000181	bic	bicaudal	bicaudal (bic) encodes the β subunit of the nascent polypeptide-associated complex. It regulates osk mRNA localization, which in turn specifies the anterior/posterior axis of the egg. [Date last reviewed: 2019-06-13]
FBgn0000183	BicD	Bicaudal D	Bicaudal D (BicD) encodes a cytoplasmic protein that links diverse cargo to the dynein/dynactin motor. Cargos like mRNAs, proteins and organelles are transported along microtubules. Through this mechanism the product of BicDcontrols spatial aspects of gene expression and polarity formation during development. Additionally, it supports physiology of differentiated polar cells and the function of the nervous system. [Date last reviewed: 2019-03-07]
FBgn0000212	brm	brahma	brahma (brm) encodes the ATPase subunit of the Brahma chromatin-remodeling complex, which is involved in transcription regulation. It regulates Egfr signalling, stem cell proliferation, and innate immune response. It contributes to multiple processes including neurogenesis, muscle development, phagocytosis, His3-K27 acetylation and leg and wing morphogenesis. [Date last reviewed: 2019-03-07]
FBgn0000221	brn	brainiac	NA
FBgn0000228	Bsg25D	Blastoderm-specific gene 25D	Blastoderm-specific gene 25D (Bsg25D) encodes the ortholog of Ninein, a microtubule-anchoring protein in humans. Bsg25D is highly expressed at blastoderm stage embryos and its product localizes to the centrosome periphery. [Date last reviewed: 2018-09-06]
FBgn0000229	bsk	basket	basket (bsk) encodes a serine/threonine-protein kinase, a key component of JNK pathway that phosphorylates the transcription factor encoded by Jra. Its roles include regulation of cell shape and stress response. [Date last reviewed: 2019-03-07]
FBgn0000239	bur	burgundy	burgundy (bur) encodes a GMP synthetase required for axon guidance. It regulates the activity of the ubiquitin protease encoded by Usp7. [Date last reviewed: 2019-09-12]
FBgn0000244	by	blistery	blistery (by) encodes fly tensin, an adaptor protein that can bind integrins and actin and colocalizes with integrins in numerous tissues. Null alleles have a mild defect in integrin adhesion, as they are adult viable with loss of adhesion between the wing epithelia. [Date last reviewed: 2019-03-07]
FBgn0000246	c(3)G	crossover suppressor on 3 of Gowen	crossover suppressor on 3 of Gowen (c(3)G) encodes the transerve filament protein of the synaptonemal complex. It is required for many meiotic processes, including homolog pairing, recombination, and chromosome segregation at meiosis I. [Date last reviewed: 2019-09-26]
FBgn0000247	ca	claret	claret (ca) encodes a protein that is required for wild-type eye color. ca mutant flies show a wine-red eye color. [Date last reviewed: 2019-03-07]
FBgn0000250	cact	cactus	cactus (cact) encodes the homolog of mammalian IkappaB. cact product acts as an inhibitor of NF-kappaB signaling by binding to the products of dl and Dif, which prevents their nuclear translocation. Toll signaling promotes the destruction of cact protein, which allows the products of dl and Dif to enter the nucleus and regulate gene expression. [Date last reviewed: 2019-03-21]
FBgn0000253	Cam	Calmodulin	Calmodulin (Cam) encodes a Calcium-binding messenger protein. It acts as a part of the calcium signal transduction pathway and interacts with various target proteins such as kinases or phosphatases. It is involved in actin filament-based movement, mitotic spinde assembly, axon guidance, DNA damage response, autophagy, cell death, sensory perception, and muscle homeostasis. [Date last reviewed: 2019-03-07]
FBgn0000256	capu	cappuccino	cappuccino (capu) encodes a formin family protein that nucleates actin filaments and accelerates their elongation. It works with the product of spir to build an actin mesh that fills the oocyte during mid-oogenesis. capu is necessary for polarity establishment and female fertility. [Date last reviewed: 2019-03-07]
FBgn0000257	car	carnation	carnation (car) encodes a subunit of the conserved HOPS complex, which is required for pigment granule formation and membrane fusion events, such as fusions between endosomes or autophagosomes with lysosomes. car loss of function mutant flies exhibit altered eye color. [Date last reviewed: 2018-09-06]
FBgn0000259	CkIIbeta	Casein kinase II beta subunit	Casein kinase II β subunit (CkIIβ) encodes the regulatory subunit of the CKII holoenzyme, a protein serine/threonine kinase composed of a and b subunits. Interactions have been reported with other kinases (e.g., the products of PIP4K and S6kII), the RNA-binding protein encoded by orb , the Hedgehog signaling pathway and clock proteins such as the products of tim and per. The product of CkIIβ functions in oogenesis, neurogenesis, development (brain and other tissues) as well as circadian behavior. [Date last reviewed: 2019-03-07]
FBgn0000261	Cat	Catalase	Catalase (Cat) encodes an enzyme that catalyzes the decomposition of hydrogen peroxide. It reduces the amount of oxidative damage to biomolecules and protects cells from the toxic effects of reactive oxygen species. [Date last reviewed: 2018-09-06]
FBgn0000273	Pka-C1	Protein kinase, cAMP-dependent, catalytic subunit 1	Protein kinase, cAMP-dependent, catalytic subunit 1 (Pka-C1) encodes a serine/threonine kinase that contributes to axis specification, rhythmic behavior and synaptic transmission. [Date last reviewed: 2019-03-14]
FBgn0000276	CecA1	Cecropin A1	Cecropin A1 (CecA1) encodes an antibacterial peptide with activity against Gram-negative bacteria. It is expressed in the fat body during the systemic immune response and in various epithelia, and it is regulated at the transcriptional level, mostly by the immune deficiency pathway. [Date last reviewed: 2019-03-07]
FBgn0000278	CecB	Cecropin B	Cecropin B (CecB) encodes an helicoidal antibacterial peptide with activity against Gram-negative bacteria. It is mostly expressed at the pupal stage. [Date last reviewed: 2019-03-07]
FBgn0000279	CecC	Cecropin C	Cecropin C (CecC) encodes an antibacterial peptide with activity against Gram-negative bacteria. It is strongly expressed at the pupal stage. [Date last reviewed: 2019-03-07]
FBgn0000283	Cp190	Centrosomal protein 190kD	NA
FBgn0000286	Cf2	Chorion factor 2	Chorion factor 2 (Cf2) encodes a zinc-finger DNA-binding transcription factor that is involved in follicle cell fate determination and regulation of myogenic gene expression. [Date last reviewed: 2019-03-07]
FBgn0000289	cg	combgap	combgap (cg) encodes a DNA binding protein that can act as a repressor or activator of gene expression depending on context. It binds to Polycomb Response Elements and is necessary to recruit Polycomb protein complexes to some of them. [Date last reviewed: 2019-03-07]
FBgn0000299	Col4a1	Collagen type IV alpha 1	Collagen type IV alpha 1 (Col4a1) encodes a subunit of Collagen IV and a major component of basement membranes. It is required for muscle and epithelium integrity. [Date last reviewed: 2019-03-07]
FBgn0000307	chif	chiffon	chiffon (chif) encodes a protein associated with the origin recognition complex that binds to chromosomal origins of replication and is required for the initiation of cellular DNA replication. It is involved in DNA replication, chorion production, muscle homeostasis, and axon guidance. [Date last reviewed: 2019-03-07]
FBgn0000308	chic	chickadee	chickadee (chic) encodes an actin monomer binding protein that provides the major cellular pool of readily polymerizing ATP-actin monomers. It is involved in oogenesis, spermatogenesis, cell division, bristle formation, cellular morphogenesis, axon growth, filopodia formation, dorsal closure, wound healing and stem cell maintenance. [Date last reviewed: 2019-03-07]
FBgn0000317	ck	crinkled	crinkled (ck) encodes a myosin VIIa homolog that is expected to have roles in cellular protrusion formation and cargo intracellular transport. ck hypomorphs are hearing defective and present abnormal chaetae and trichomes. [Date last reviewed: 2018-09-06]
FBgn0000318	cl	clot	clot (cl) encodes a protein with thioredoxin reductase and glutathione peroxidase enzymatic activity. cl is required for drosopterin biosynthesis and its product contributes to redox homeostasis and signaling and defence against oxidative stress. [Date last reviewed: 2018-09-06]
FBgn0000319	Chc	Clathrin heavy chain	Clathrin heavy chain (Chc) encodes a protein that forms part of the clathrin complex, which is the major component of coated vesicles. [Date last reviewed: 2019-03-07]
FBgn0000326	clt	cricklet	NA
FBgn0000330	cm	carmine	NA
FBgn0000339	cni	cornichon	NA
FBgn0000346	comt	comatose	comatose (comt) encodes the N-ethylmaleimide-Sensitive Factor 1 protein. It is required for maintenance of neurotransmitter release through disassembly or rearrangement of plasma membrane SNARE complexes following synaptic vesicle fusion. [Date last reviewed: 2019-03-07]
FBgn0000351	cort	cortex	cortex (cort) encodes a member of the Cdc20 family of activators of the Anaphase Promoting Complex (APC). It activates the APC specifically in the oocyte to release the metaphase I arrest, permitting completion of meiosis and several egg activation events. [Date last reviewed: 2019-03-07]
FBgn0000352	cos	costa	costa (cos) encodes a kinesin-like protein and a key component in the Hedgehog (Hh) pathway that is involved in pattern formation and growth control. It forms a complex with the product of fu to restrict the activity of the Hh pathway transcription factor encoded by ci. [Date last reviewed: 2019-03-07]
FBgn0000370	crc	cryptocephal	cryptocephal (crc) encodes a protein that belongs to a member of the CREB/ATF family of basic-leucine zipper transcription factors. It serves as an coactivator of the product EcR of to promote expression the molting peptide hormone encoded by ETH. It also acts as an unfolded protein response transcription factor to regulate glycolytic genes in response to ER stress. [Date last reviewed: 2019-03-07]
FBgn0000376	crm	cramped	NA
FBgn0000377	crn	crooked neck	crooked neck (crn) encodes a component of the splicing complex involved in axon ensheathment, glial cell migration and Malpighian tubule morphogenesis. [Date last reviewed: 2018-09-06]
FBgn0000382	csw	corkscrew	corkscrew (csw) encodes a non receptor tyrosine phosphatase acting downstream of receptor tyrosine kinases (RTKs) such as Egfr, tor and FGF RTKs. The product of csw contributes to growth regulation, cell survival and developmental patterning. [Date last reviewed: 2018-09-06]
FBgn0000384	cta	concertina	NA
FBgn0000394	cv	crossveinless	crossveinless (cv) encodes a member of the tumor suppressor gene family of BMP binding proteins. Its primary function is to help specify the posterior crossvein during pupal wing development by enhancing Dpp/Gbb signaling. [Date last reviewed: 2019-03-07]
FBgn0000395	cv-2	crossveinless 2	crossveinless 2 (cv-2) encodes a secreted protein that binds BMPs, the BMP receptor encoded by tkv and Heparan Sulfate Proteoglycans. It either promotes BMP signaling, as in the developing crossveins, or inhibits BMP signaling, as in the early embryo. [Date last reviewed: 2019-03-07]
FBgn0000404	CycA	Cyclin A	Cyclin A (CycA) encodes a protein that binds to the product of Cdk1, thereby promoting Cdk1's protein kinase activity. The CycA-Cdk1 complex controls important aspects of progression through the cell cycle, including entry into mitosis. During the G2 phase, this complex is important for prevention of premature DNA re-replication. During mitosis and G1, the product of CycA is rapidly degraded (involving APC/C and the proteasome), resulting in inactivation of Cdk1 protein kinase activity. [Date last reviewed: 2019-03-07]
FBgn0000405	CycB	Cyclin B	Cyclin B (CycB) encodes a protein that binds to Cdk1, thereby promoting Cdk1's protein kinase activity. The complex CycB-Cdk1 complex induces the start of mitosis. During late metaphase of mitosis and continuing in G1, the product of CycB is rapidly degraded (involving APC/C and the proteasome), resulting in inactivation of Cdk1 protein kinase activity, and allowing termination of mitosis. [Date last reviewed: 2019-03-07]
FBgn0000406	Cyt-b5-r	Cytochrome b5-related	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0000412	D1	D1 chromosomal protein	D1 chromosomal protein (D1) encodes a multi-AT-hook chromosomal protein that associates with AT-rich satellites, including the SAT-III repeats of the X-chromosome. The product of D1 binds to the minor-groove of the DNA and favors heterochromatin-mediated gene repression involving its interaction with topoisomerase II. [Date last reviewed: 2018-09-06]
FBgn0000414	Dab	Disabled	Disabled (Dab) encodes an adaptor protein that is a core component of the Abl tyrosine kinase signaling pathway. It associates with transmembrane receptors including those encoded by N and Appl. It is involved in axon patterning, embryo morphogenesis and trafficking in endocytosis, exocytosis and Golgi organization. [Date last reviewed: 2019-03-07]
FBgn0000416	Sap-r	Saposin-related	Saposin-related (Sap-r) encodes the single protein precursor of several sphingolipid activator proteins (Saposins). Loss of Sap-r leads to the accumulation of sphingolipids in lysosomes, resulting in lysosomal dysfunction, defective lipid homeostasis and neurodegeneration. [Date last reviewed: 2018-09-06]
FBgn0000426	SmF	Small ribonucleoprotein particle protein SmF	Small ribonucleoprotein particle protein SmF (SmF) encodes an RNA binding protein that functions as part of a heteroheptameric ring structure called the Sm core. This complex binds to spliceosomal small nuclear RNAs (e.g. U1, U2, U4 and U5) and helps to carry out pre-mRNA splicing. It also forms a heterotrimeric sub-complex with the products of SmE and SNRPG. [Date last reviewed: 2019-03-14]
FBgn0000447	Dhod	Dihydroorotate dehydrogenase	Dihydroorotate dehydrogenase (Dhod) encodes a protein that is associated with the inner mitochondrial membrane. It catalyzes the fourth step of de novo pyrimidine biosynthesis, which is required for normal cuticle formation and oogenesis. [Date last reviewed: 2019-03-07]
FBgn0000454	Dip-B	Dipeptidase B	Dipeptidase B (Dip-B) encodes a peptidase involved in protein metabolism. [Date last reviewed: 2019-09-12]
FBgn0000455	Dip-C	Dipeptidase C	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0000464	Lar	Leukocyte-antigen-related-like	Leukocyte-antigen-related-like (Lar) encodes a transmembrane receptor tyrosine phosphatase with a extracellular domain that binds to the product of Sdc. It regulates signaling through the product of Abl. While the product of Lar has many functions, it is best known for its roles in embryonic motor axon guidance and in target recognition by axons of R7 photoreceptors. [Date last reviewed: 2019-03-14]
FBgn0000479	dnc	dunce	dunce (dnc) encodes a cAMP-specific phosphodiesterase, responsible for cAMP degradation. dnc product plays a pivotal role in neurological and behavioral plasticity including synaptic development and function, learning and courtship. The product of dnc is also known to affect regulation of several developmental processes such as oogenesis. [Date last reviewed: 2019-03-21]
FBgn0000482	dor	deep orange	NA
FBgn0000489	Pka-C3	Protein kinase, cAMP-dependent, catalytic subunit 3	NA
FBgn0000490	dpp	decapentaplegic	decapentaplegic (dpp) encodes a ligand of the transforming growth factor-β signaling pathway that signals through Smad transcription factors. It acts as a morphogen that contributes to growth regulation, patterning and stem cell fate. [Date last reviewed: 2019-08-01]
FBgn0000499	dsh	dishevelled	NA
FBgn0000520	dwg	deformed wings	deformed wings (dwg) encodes an architectural chromatin protein essential for embryonic development that organizes open chromatin in regulatory regions (predominantly promoters). dwg product binding site was found in the insulator encoded by scs, and its functions include enhancer blocking, support of distant interactions and recruitment of transcription factors. [Date last reviewed: 2019-03-07]
FBgn0000524	dx	deltex	NA
FBgn0000527	e	ebony	ebony (e) encodes a protein that links beta-alanine to biogenic amines like dopamine or histamine. It controls the amount of free biogenic amine, e.g. of dopamine in cuticle formation and of histamine in visual signal transduction of the eye. It is also involved in behavioral rhythmicity. [Date last reviewed: 2019-03-07]
FBgn0000535	eag	ether a go-go	NA
FBgn0000536	eas	easily shocked	NA
FBgn0000541	E(bx)	Enhancer of bithorax	NA
FBgn0000542	ec	echinus	echinus (ec) encodes a protein phosphatase 1 (PP1) binding protein involved in interommatidial cell sorting and cell death. [Date last reviewed: 2019-07-11]
FBgn0000543	ecd	ecdysoneless	ecdysoneless (ecd) encodes a protein that physically interacts with several components of the U5 snRPN pre-mRNA splicing complex. Its loss result in intron retention within spok, accounting for ecdysone deficiency of some ecd mutants. [Date last reviewed: 2019-03-07]
FBgn0000546	EcR	Ecdysone receptor	Ecdysone receptor (EcR) encodes a protein that interacts with the product of usp to form the nuclear ecdysone receptor heterodimer, which modulates, in conjunction with co-activators and co-repressors, the activities of hundreds of genes in a tissue- and stage-specific way. EcR is widely expressed in embryonic and larval tissues and in some adult tissues where its activities (modulated by the hormone ecdysone) trigger both molting and metamorphosis. [Date last reviewed: 2019-03-07]
FBgn0000547	ed	echinoid	echinoid (ed) encodes a cell adhesion molecule of adherens junctions that mediate cell adhesion/recognition. It participates in multiple signaling pathways including Egfr, Notch and Hippo during organogenesis. It is also required in multiple steps of dorsal closure during embryogenesis. [Date last reviewed: 2019-03-07]
FBgn0000557	eEF1alpha2	eukaryotic translation elongation factor 1 alpha 2	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0000559	eEF2	eukaryotic translation elongation factor 2	NA
FBgn0000562	egl	egalitarian	egalitarian (egl) encodes an RNA binding protein that links specific mRNAs to the minus end-directed microtubule motor, cytoplasmic dynein-1. [Date last reviewed: 2018-09-13]
FBgn0000565	MsrA	Methionine sulfoxide reductase A	Ecdysone-induced protein 28/29kD (Eip71CD) encodes a methionine-S-sulfoxide reductase involved in the response to oxidative stress. It contributes to determination of adult lifespan and neuron projection. [Date last reviewed: 2019-03-07]
FBgn0000566	Eip55E	Ecdysone-induced protein 55E	Ecdysone-induced protein 55E (Eip55E) encodes a protein involved in glutathione biosynthesis. [Date last reviewed: 2019-09-12]
FBgn0000567	Eip74EF	Ecdysone-induced protein 74EF	Ecdysone-induced protein 74EF (Eip74EF) encodes a transcription factor that responds to different concentrations of 20-hydroxyecdysone. It contributes to puparium formation and autophagy. [Date last reviewed: 2019-03-07]
FBgn0000568	Eip75B	Ecdysone-induced protein 75B	Ecdysone-induced protein 75B (Eip75B) encodes a nuclear receptor that interacts with the receptor encoded by Hr3. The product of Eip75B regulates feeding behavior, fat deposition, and developmental timing in response to nitric oxide (NO) signaling. It also acts downstream from NO in the nervous system, where it controls neuronal remodeling. [Date last reviewed: 2018-09-13]
FBgn0000575	emc	extra macrochaetae	NA
FBgn0000578	ena	enabled	enabled (ena) encodes the sole Drosophila member of the Ena/VASP family. It acts as a processive actin polymerase, stimulating actin addition at the barbed end. It has roles in both epithelial morphogenesis and CNS pathfinding. [Date last reviewed: 2019-03-07]
FBgn0000579	Eno	Enolase	Enolase (Eno) encodes a phosphopyruvate hydratase involved in glucose homeostasis. [Date last reviewed: 2019-09-12]
FBgn0000581	E(Pc)	Enhancer of Polycomb	Enhancer of Polycomb (E(Pc)) encodes a chromatin protein that functions as a suppressor of position-effect variegation. An unusual member of the Polycomb group; it does not exhibit homeotic transformations on its own, but rather enhances mutations in other Polycomb group genes. It forms part of the TIP60 histone acetyltransferase complex, which has been involved in many processes, including both transcriptional activation and repression. [Date last reviewed: 2019-09-26]
FBgn0000588	esc	extra sexcombs	extra sexcombs (esc) encodes an essential component of Polycomb Repressive Complex 2 (PRC2), which antagonizes chromatin opening and can be targeted to silence developmental genes. [Date last reviewed: 2019-03-07]
FBgn0000611	exd	extradenticle	extradenticle (exd) encodes a homeodomain transcription factor that is imported to the nuclueus upon binding the product of hth. The protein complex hth-exd are Hox cofactors but also have additional Hox-independent functions such as in antennal development, proximal appendages patterning, and cell division promotion of the undifferentiated eye field. [Date last reviewed: 2019-03-21]
FBgn0000615	exu	exuperantia	NA
FBgn0000617	Taf9	TBP-associated factor 9	TBP-associated factor 9 (Taf9) encodes a main component of the Transcription factor II D (TFIID) complex. TFIID is involved in recruiting the transcription machinery to core promoters and organizing specific enhancer-promoter interactions. [Date last reviewed: 2019-09-26]
FBgn0000618	e(y)2	enhancer of yellow 2	enhancer of yellow 2 (e(y)2) encodes a subunit of TREX2 mRNA nuclear export complex. It is also a subunit of histone deubiquitination module of SAGA complex. The product of e(y)2 is essential for general nuclear export of mRNA, transcription activation and gene positioning in the nuclei. [Date last reviewed: 2019-09-26]
FBgn0000629	E(z)	Enhancer of zeste	Enhancer of zeste (E(z)) encodes the catalytic component of the Polycomb Repressive Complex 2 (PRC2) methyltransferase that methylates histone H3 lysine27. Together with PRC1, PRC2 silences developmental genes to determine specific differentiated cell identities. [Date last reviewed: 2019-09-26]
FBgn0000635	Fas2	Fasciclin 2	NA
FBgn0000636	Fas3	Fasciclin 3	Fasciclin 3 (Fas3) encodes a cell adhesion molecule expressed by subsets of motoneurons and muscle cells in the embryonic/larval motor system. [Date last reviewed: 2019-03-07]
FBgn0000662	fl(2)d	female lethal d	NA
FBgn0000667	Actn	alpha actinin	α actinin (Actn) encodes an actin cross-linking protein with muscle and non-muscle specific isoforms, which are produced by alternative spicing. The muscle isoform has a role in muscle development while the non-muscle isoform localizes to ovarian ring canals and has a role in cytoskeletal remodeling of follicle cells. [Date last reviewed: 2019-03-07]
FBgn0000709	fliI	flightless I	NA
FBgn0000711	flw	flapwing	NA
FBgn0000719	fog	folded gastrulation	folded gastrulation (fog) encodes a secreted ligand that signals via GPCRs to co-ordinate cell shape change during gastrulation; in the nervous system, it regulates motor axon guidance, glial organization and morphogenesis. [Date last reviewed: 2019-03-07]
FBgn0000721	for	foraging	foraging (for) encodes a serine/threonine kinase and a member of the protein kinase G family. For roles include feeding, locomotion, metabolism, development, olfactory habituation, learning and memory, stress, social behavior, as well as Malpighian tubule, heart, muscle and synaptic function. [Date last reviewed: 2019-03-07]
FBgn0000723	FER	FER tyrosine kinase	NA
FBgn0000808	gd	gastrulation-defective	gastrulation-defective (gd) encodes a secreted serine protease. It is a member of the protease cascade that generates the ligand that activates the receptor encoded by Tl. It contributes to establishment of the dorsal-ventral embryonic axis. [Date last reviewed: 2019-03-07]
FBgn0000810	fs(1)K10	female sterile (1) K10	female sterile (1) K10 (fs(1)K10) encodes a nuclear protein of unknown biochemical function required during oogenesis for the proper localization of grk mRNA and protein in the oocyte, a key step in the specification of the dorsoventral axis of the oocyte, mature egg, and future embryo. [Date last reviewed: 2019-09-26]
FBgn0000826	png	pan gu	pan gu (png) encodes a Ser/Thr kinase that controls the translation of hundreds of mRNAs, such as CycB and smg, during the oocyte-to-embryo transition. The activation of the product of png requires the formation of a complex with the two activating subunits encoded by plu and gnu. [Date last reviewed: 2019-03-14]
FBgn0000927	fs(1)Ya	female sterile (1) Young arrest	female sterile (1) Young arrest (fs(1)Ya) encodes a maternally-expressed protein that is required for mitotic phase initiation during early embryogenesis. It localizes in the nuclear lamina of the embryo, and binds DNA and the product of His2B. In developing oocytes the product of fs(1)Ya is cytoplasmic, but enters nuclei when it is dephosphorylated during egg activation. [Date last reviewed: 2019-09-26]
FBgn0000928	fs(1)Yb	female sterile (1) Yb	female sterile (1) Yb (fs(1)Yb) encodes a protein involved in maintenance of the germ-line stem cell population during oogenesis. [Date last reviewed: 2019-09-26]
FBgn0000996	dup	double parked	double parked (dup) encodes an essential protein for the initiation of DNA replication due to its recruitment of the MCM helicase to replication origins. [Date last reviewed: 2019-03-07]
FBgn0001075	ft	fat	fat (ft) is a tumor suppressor gene that encodes a large cadherin family transmembrane protein. It functions in the Hippo signaling pathway (as a receptor) and the Dachsous-Fat planar cell polarity pathway (as a transmembrane component). [Date last reviewed: 2019-03-07]
FBgn0001078	ftz-f1	ftz transcription factor 1	NA
FBgn0001079	fu	fused	NA
FBgn0001083	fw	furrowed	furrowed (fw) encodes a selectin that mediates the interaction of planar cell polarity proteins by stabilizing the product of fz. [Date last reviewed: 2019-09-12]
FBgn0001084	fy	fuzzy	fuzzy (fy) encodes a cytoplasmic protein that functions as a downstream member of the fz-stan planar cell polarity pathway that controls hair and bristle polarity in the adult. It interacts directly with the product of in and accumulates on the proximal edge of wing cells. [Date last reviewed: 2019-03-07]
FBgn0001086	fzy	fizzy	fizzy (fzy) encodes WD40 domain protein required for the full ubiquitin ligase activity of the anaphase-promoting complex/cyclosome (APC/C) in mitosis and meiosis. The product of fzy functions to target substrates for destruction and drive metaphase and anaphase transition. [Date last reviewed: 2018-09-13]
FBgn0001087	g	garnet	garnet (g) encodes a protein that forms the Adaptor protein 3 (AP-3) complex together with the other subunits encoded by or, rb and cm. These complexes select cargo for inclusion into vesicles for transport within the cell. AP-3 delivers protein cargo to a number of specialized organelles including pigment granules, late endosomes, lysosomes and synaptic vesicles. AP-3 genes were first found through defects in pigment granules that alter eye color. [Date last reviewed: 2019-03-07]
FBgn0001090	bnb	bangles and beads	NA
FBgn0001091	Gapdh1	Glyceraldehyde 3 phosphate dehydrogenase 1	Glyceraldehyde 3 phosphate dehydrogenase 1 (Gapdh1) encodes a glyceraldehyde-3-phosphate dehydrogenase involved in glycolysis, myoblast fusion and the development of somatic muscle. [Date last reviewed: 2019-09-19]
FBgn0001092	Gapdh2	Glyceraldehyde 3 phosphate dehydrogenase 2	Glyceraldehyde 3 phosphate dehydrogenase 2 (Gapdh2) encodes a glyceraldehyde-3-phosphate dehydrogenase involved in glucose homeostasis. [Date last reviewed: 2019-09-19]
FBgn0001098	Gdh	Glutamate dehydrogenase	Glutamate dehydrogenase (Gdh) encodes a glutamate dehydrogenase involved glutamate metabolism. [Date last reviewed: 2019-09-19]
FBgn0001104	Galphai	G protein alpha i subunit	NA
FBgn0001105	Gbeta13F	G protein beta-subunit 13F	G protein β-subunit 13F (Gβ13F) encodes an ubiquitous, maternal product required for gastrulation movements of early embryo and regulating medial (mesoderm and ectoderm) and junctional Myosin II (ectoderm) via RhoI pathway. The product of Gβ13F is detected apically and at adherens junctions. [Date last reviewed: 2019-09-26]
FBgn0001108	DCTN1-p150	Dynactin 1, p150 subunit	Dynactin 1, p150 subunit (DCTN1-p150) encodes the p150 subunit of the dynactin complex. Dynactin is thought to act as a dynein receptor that modulates binding of dynein to cellular cargoes and enhances the processivity of dynein movement. The roles of the product of DCTN1-p150 include oocyte polarity, mitotic cell division, embryonic development, neuronal transport and neurogenesis. [Date last reviewed: 2019-03-07]
FBgn0001114	Glt	Glutactin	Glutactin (Glt) encodes a secreted protein that belongs to the family of cholinesterase/carboxylesterase-like proteins but lacks the catalytically active residues. It forms part of the basement membrane and regulates axonal outgrowth. [Date last reviewed: 2019-03-07]
FBgn0001122	Galphao	G protein alpha o subunit	G protein α o subunit (Gαo) encodes the most abundant G protein in the nervous tissue and is involved in signaling by a variety of GPCRs. It contributes to heart development, axonogenesis, neuro-muscular junction formation, asymmetric cell division, planar cell polarity, blood-brain barrier establishment, Wnt signaling, and gustatory and olfactory sensory perception. [Date last reviewed: 2019-03-07]
FBgn0001123	Galphas	G protein alpha s subunit	G protein α s subunit (Gαs) encodes an alpha subunit of the class of heterotrimeric G proteins, found on the cytosolic face of the plasma membrane. An inactive GDP-bound form forms a heterotrimer with beta and gamma subunits. On activation by a 7-TM receptor, the product of Gαs exchanges GDP for GTP, dissociates from the trimer, and activates adenylyl cyclase, thus initiating cAMP signaling. Gαs roles include neurophysiology, and behaviors including learning. [Date last reviewed: 2019-09-26]
FBgn0001124	Got1	Glutamate oxaloacetate transaminase 1	Glutamate oxaloacetate transaminase 1 (Got1) encodes an L-aspartate:2-oxoglutarate aminotransferase involved in glutamate biosynthesis. [Date last reviewed: 2019-09-12]
FBgn0001125	Got2	Glutamate oxaloacetate transaminase 2	Glutamate oxaloacetate transaminase 2 (Got2) encodes an L-aspartate:2-oxoglutarate aminotransferase involved in glutamate biosynthesis, which in turn regulates postsynaptic receptor field size. [Date last reviewed: 2019-09-12]
FBgn0001128	Gpdh1	Glycerol-3-phosphate dehydrogenase 1	Glycerol-3-phosphate dehydrogenase 1 (Gpdh1) encodes a glycerol-3-phosphate dehydrogenase that catalyzes the oxidation of glycerol-3-phosphate to dihydroxyacetone phosphate. It is involved in triglyceride metabolism, response to hyperoxia and flight behavior. [Date last reviewed: 2019-09-26]
FBgn0001133	grau	grauzone	grauzone (grau) encodes a transcription factor with the Cdc20 activator of the Anaphase Promoting Complex (APC) encoded by cort as key target. Absence of grau function results in the cort phenotype of female sterility, meiosis II arrest, and egg activation defects. [Date last reviewed: 2019-03-07]
FBgn0001137	grk	gurken	gurken (grk) encodes a TGFα family signaling ligand that activates the intracellular MAP kinase pathway via the the product of Egfr. The asymmetrical localization of grk mRNA is key for its function during oogenesis, to establish anterior-posterior and dorso-ventral axes in the egg and embryo. [Date last reviewed: 2019-03-07]
FBgn0001139	gro	groucho	groucho (gro) encodes a global developmental co-repressor in conjunction with manifold DNA-binding repressor partner proteins, which tether it to target promoters. It functions downstream of key signaling pathways such as Wg/Wnt and Dpp/TGF-beta. Notably, phosphorylation of the product of gro in response to MAPK activation weakens its repressor capacity. [Date last reviewed: 2019-03-07]
FBgn0001142	Gs1	Glutamine synthetase 1	Glutamine synthetase 1 (Gs1) encodes the mitochondrial enzyme that uses glutamate and ammonia as substrates to synthesize glutamine, which is a precursor of purine and pyrimidine synthesis. An adequate level of maternally supplied Gs1 product activity is necessary in the early embryonic development. High level of glutamine in mitochondria causes megamitochondrial formation in cells. [Date last reviewed: 2018-09-13]
FBgn0001145	Gs2	Glutamine synthetase 2	Glutamine synthetase 2 (Gs2) encodes an enzyme that converts glutamate to glutamine. It is expressed in the embryonic nervous system and regulates the size of glutamate neurotransmitter pools and synapse assembly. [Date last reviewed: 2019-03-07]
FBgn0001149	GstD1	Glutathione S transferase D1	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0001150	gt	giant	"giant (gt) encodes a transcription factor in the basic leucine zipper family. It is one of the ""gap"" transcription factors, transcribed very early in embryonic development, that help to divide the embryo along the anteroposterior axis. [Date last reviewed: 2019-03-07]"
FBgn0001168	h	hairy	hairy (h) encodes a bHLH transcriptional repressor that recruits the corepressor encoded by gro to target promoters. It is a pair-rule gene that contributes to embryonic segmentation and peripheral neurogenesis. [Date last reviewed: 2019-03-07]
FBgn0001169	H	Hairless	Hairless (H) encodes the major antagonist of Notch signaling activity during imaginal development. It silences target genes of the product of N by assembling a transcriptional repressor complex, which includes the transcription factor encoded by Su(H) and general co-repressors like those encoded by gro and CtBP. [Date last reviewed: 2019-03-07]
FBgn0001179	hay	haywire	haywire (hay) encodes a ATP-dependent 3'-5' DNA helicase based on the similarity with the human gene XPB, which is a subunit of the DNA repair and basal transcription factor TFIIH. The product of hay contributes to response to UV and homeotic gene expression. [Date last reviewed: 2018-09-13]
FBgn0001185	her	hermaphrodite	hermaphrodite (her) encodes a zinc finger C2H2 transcription factor involved in sex determination and differentiation. [Date last reviewed: 2019-06-13]
FBgn0001186	Hex-A	Hexokinase A	Hexokinase A (Hex-A) encodes a hexokinase involved in glucose homeostasis. [Date last reviewed: 2019-09-12]
FBgn0001189	hfw	halfway	NA
FBgn0001197	His2Av	Histone H2A variant	Histone H2A variant (His2Av) encodes a protein that is present in about 25% of nucleosomes. It influences chromatin structure and gene regulation and is also phosphorylated in response to DNA damage in the less conserved C-terminal tail. [Date last reviewed: 2019-03-07]
FBgn0001202	hook	hook	NA
FBgn0001206	Hmr	Hybrid male rescue	Hybrid male rescue (Hmr) encodes a protein required to repress transposable element and satellite DNA expression. It also has a gain-of-function phenotype of causing lethality in F1 male hybrids between D. melanogaster and D. simulans. [Date last reviewed: 2019-03-07]
FBgn0001215	Hrb98DE	Heterogeneous nuclear ribonucleoprotein at 98DE	Heterogeneous nuclear ribonucleoprotein at 98DE (Hrb98DE) encodes a nuclear RNA-binding protein. It controls hnRNA stability, splicing, IRES-dependent translation, and translational repression. It represents one of the main targets of the poly(ADP-ribosyl)ation pathway. It also regulates tissue polarity patterning and germ-line stem cell fate. [Date last reviewed: 2019-03-07]
FBgn0001218	Hsc70-3	Heat shock 70-kDa protein cognate 3	NA
FBgn0001220	Hsc70-5	Heat shock protein cognate 5	NA
FBgn0001222	Hsf	Heat shock factor	NA
FBgn0001224	Hsp23	Heat shock protein 23	Heat shock protein 23 (Hsp23) encodes a protein involved in protein folding. It contributes to the response to cold, heat and hypoxia. [Date last reviewed: 2019-09-12]
FBgn0001225	Hsp26	Heat shock protein 26	Heat shock protein 26 (Hsp26) encodes a protein involved in protein folding. It contributes to lifespan determination and the response to cold and heat. [Date last reviewed: 2019-09-12]
FBgn0001226	Hsp27	Heat shock protein 27	Heat shock protein 27 (Hsp27) encodes a member of the ATP-independent, small heat shock protein family. It contributes to regulation of eye morphology, polyglutamine toxicity, lifespan and starvation tolerance. [Date last reviewed: 2019-03-07]
FBgn0001230	Hsp68	Heat shock protein 68	Heat shock protein 68 (Hsp68) encodes a protein involved in lifespan determination and response to heat shock and starvation. [Date last reviewed: 2019-08-01]
FBgn0001233	Hsp83	Heat shock protein 83	NA
FBgn0001234	lncRNA:Hsromega	Heat shock RNA omega	Heat shock RNA ω (lncRNA:Hsrω) is a developmentally expressed and stress-inducible long non-coding RNA gene, producing multiple nuclear and cytoplasmic transcripts. The long nuclear transcripts, in association with various heterogeneous nuclear ribonucleoproteins (hnRNPs), organize nucleoplasmic omega speckles to regulate multiple cellular processes. [Date last reviewed: 2021-03-18]
FBgn0001247	Ide	Insulin degrading metalloproteinase	Insulin degrading metalloproteinase (Ide) encodes a metalloprotease that controls growth in a cell-autonomous manner by regulating the level of the insulin-like peptide encoded by Ilp2. [Date last reviewed: 2018-09-13]
FBgn0001248	Idh	Isocitrate dehydrogenase	Isocitrate dehydrogenase (Idh) encodes a cytosolic enzyme that catalyzes the oxidative decarboxylation of isocitrate to 2-oxoglutarate, with the concomitant reduction of NADP[+] to NADPH. It functions, along with Men, Zw, and Pgd, in a small network of NADP reducing enzymes. [Date last reviewed: 2019-03-07]
FBgn0001250	if	inflated	inflated (if) encodes one of five fly integrin alpha subunits, and when in a heterodimer with an integrin beta subunit makes a receptor for extracellular matrix proteins containing an RGD motif, such as those encoded by Tig, wb laminin and Tsp. It is required in numerous tissues for cell migration and adhesion between cell layers. [Date last reviewed: 2019-03-07]
FBgn0001257	ImpL2	Ecdysone-inducible gene L2	NA
FBgn0001258	Ldh	Lactate dehydrogenase	Lactate dehydrogenase (Ldh) encodes a protein involved in myoblast fusion and somatic muscle development. [Date last reviewed: 2019-09-19]
FBgn0001263	inaD	inactivation no afterpotential D	inactivation no afterpotential D (inaD) encodes a scaffolding protein that functions in the localization of the signaling proteins encoded by trp, inaC, and norpA to the rhabdomere. It also functions in the fast light-induced signaling of photoreceptors. [Date last reviewed: 2019-03-07]
FBgn0001276	ix	intersex	NA
FBgn0001280	janA	janus A	NA
FBgn0001291	Jra	Jun-related antigen	Jun-related antigen (Jra) encodes a homologue of the mammalian transcription factor Jun and has pleiotropic roles in the CNS. Jra activity is regulated by many upstream enzymes, including bsk. [Date last reviewed: 2021-01-21]
FBgn0001296	kar	karmoisin	karmoisin (kar) encodes a protein involved in ommochrome biosynthesis. [Date last reviewed: 2019-09-12]
FBgn0001297	kay	kayak	kayak (kay) encodes a transcription factor involved in multiple biological processes including cell polarity, wound healing, germ cell and eye development and cell cycle. [Date last reviewed: 2019-03-14]
FBgn0001301	kel	kelch	kelch (kel) encodes a substrate targeting component of a Cullin3-RING ubiquitin E3 ligase. It binds F-actin in vitro, while its predominant in vivo function is in the ubiquitin-proteasome pathway. It has an essential role in oogenesis, where it is required for cytoskeletal organization in ovarian ring canals. [Date last reviewed: 2019-03-14]
FBgn0001308	Khc	Kinesin heavy chain	"Kinesin heavy chain (Khc) encodes the force generating subunit of kinesin-1, a microtubule motor protein. It functions in the long-distance transport of cytoplasmic ""cargoes"" such as mRNAs, protein complexes, and organelles. [Date last reviewed: 2019-03-14]"
FBgn0001316	klar	klarsicht	klarsicht (klar) encodes a member of the Nesprin family that links microtubule motors and various cellular structures. It controls the migration and positioning of nuclei in photoreceptors and muscles. It also regulates the motion of RNP granules in oocytes and lipid droplets in embryos. [Date last reviewed: 2019-03-14]
FBgn0001324	kto	kohtalo	kohtalo (kto) encodes a subunit of the kinase module of the mediator complex. It is not required for all the transcriptional functions of mediator, but links it to a set of transcription factors that are involved in developmental signaling. [Date last reviewed: 2019-03-14]
FBgn0001330	kz	kurz	NA
FBgn0001341	Mybbp1A	MYB binding protein 1a	NA
FBgn0001404	egh	egghead	NA
FBgn0001491	l(1)10Bb	lethal (1) 10Bb	NA
FBgn0001565	Hlc	Helicase	NA
FBgn0001612	Grip91	Gamma-tubulin ring protein 91	Gamma-tubulin ring protein 91 (Grip91) encodes a gamma-tubulin binding protein involved in male meiotic division and the organization of the meiotic spindle. [Date last reviewed: 2019-09-12]
FBgn0001624	dlg1	discs large 1	NA
FBgn0001941	ifc	infertile crescent	NA
FBgn0001942	eIF4A	eukaryotic translation initiation factor 4A	eukaryotic translation initiation factor 4A (eIF4A) encodes an essential DEAD-box RNA helicase protein and a canonical translation initiation factor. It is a component of the eIF4F cap-binding complex that is essential for cap-dependent translation of mRNA. [Date last reviewed: 2019-03-07]
FBgn0001961	Arpc1	Actin-related protein 2/3 complex, subunit 1	Actin-related protein 2/3 complex, subunit 1 (Arpc1) encodes one of seven components of the highly conserved Arp2/3 complex. The Arp2/3 complex is required for many cellular and developmental processes requiring F-actin polymerization, including germline ring canal growth, embryonic cellularization, myoblast fusion, and endocytosis. [Date last reviewed: 2019-03-07]
FBgn0001965	Sos	Son of sevenless	NA
FBgn0001977	CIAPIN1	Cytokine induced apoptosis inhibitor 1	Cytokine induced apoptosis inhibitor 1 (CIAPIN1) encodes a protein required for chamber development, follicle cell proliferation and survival. [Date last reviewed: 2019-03-07]
FBgn0001978	stc	shuttle craft	shuttle craft (stc) encodes a zinc finger transcription factor of the NFX1 family. Maternally contributed protein is essential for segmentation. During the late stages of embryonic neurogenesis, zygotically expressed stc product is involved in axon guidance, which is vital for proper muscle innervation. stc expression in the embryo is important for the adult life span and aging. [Date last reviewed: 2018-09-13]
FBgn0001986	Mtr4	Mtr4 helicase	Mtr4 helicase (Mtr4) encodes an RNA helicase involved in the viral defense response. [Date last reviewed: 2019-09-19]
FBgn0001987	Gli	Gliotactin	Gliotactin (Gli) encodes a transmembrane protein localized at tricellular junctions that is necessary for septate junction and permeability barrier formation. [Date last reviewed: 2019-03-07]
FBgn0001989	ND-B17	NADH dehydrogenase (ubiquinone) B17 subunit	NA
FBgn0001990	wek	weckle	weckle (wek) encodes a zinc finger adaptor protein of the Toll signaling pathway in embryonic dorsoventral patterning. It facilitates the recruitment of the product of Myd88 to the receptor encoded by Tl. However, the product of wek is dispensable for Toll-mediated innate immunue response. [Date last reviewed: 2019-03-21]
FBgn0001994	crp	cropped	cropped (crp) encodes a transcription factor that controls cellular branching of the terminal cells at the ends of tracheal tubes. As a downstream target gene of the product of Myc, it affects cell growth, organ size and survival. [Date last reviewed: 2019-03-07]
FBgn0001995	mRpL4	mitochondrial ribosomal protein L4	NA
FBgn0002021	l(2)37Bb	lethal (2) 37Bb	NA
FBgn0002022	Catsup	Catecholamines up	NA
FBgn0002031	l(2)37Cc	lethal (2) 37Cc	NA
FBgn0002036	CG10561	NA	NA
FBgn0002044	swm	second mitotic wave missing	NA
FBgn0002069	AspRS	Aspartyl-tRNA synthetase	Aspartyl-tRNA synthetase (AspRS) is an essential gene that is predicted to encode an aspartate-tRNA ligase. It functions as a Sxl dosage-sensitive maternal modifier. [Date last reviewed: 2019-08-01]
FBgn0002121	l(2)gl	lethal (2) giant larvae	lethal (2) giant larvae (l(2)gl) encodes a tumor suppressor protein that regulates cell polarity and asymmetric cell division. It acts on the basolateral side of epithelial cells, antagonizing the activity of apical complex proteins encoded by baz, par-6 and aPKC. [Date last reviewed: 2019-09-26]
FBgn0002174	CG5504	NA	NA
FBgn0002183	dre4	dre4	dre4 (dre4) encodes a chromatin regulator that, along with the product of Ssrp, forms the facilitates chromatin transcription (FACT) protein complex. FACT facilitates GAGA factor-directed chromatin remodeling. [Date last reviewed: 2019-03-07]
FBgn0002283	l(3)73Ah	lethal (3) 73Ah	NA
FBgn0002284	Prosbeta6	Proteasome beta6 subunit	NA
FBgn0002354	l(3)87Df	lethal (3) 87Df	lethal (3) 87Df (l(3)87Df) encodes an essential locus required in embryos, early larvae, late pupae and oogenesis. [Date last reviewed: 2019-09-26]
FBgn0002413	dco	discs overgrown	discs overgrown (dco) encodes a Ser/Thr protein kinase that functions in the circadian rhythm pathway to phosphorylate and bind with circadian target proteins such as the product of per. It also contributes to Hedgehog and Wnt pathways, cell death, neurodegeneration, hyperplasia and planar cell polarity. [Date last reviewed: 2019-03-07]
FBgn0002431	hyd	hyperplastic discs	hyperplastic discs (hyd) encodes a ubiquitin ligase that is required for Wg signal response in wing discs. It catalyzes the ubiquitylation of the transcriptional co-repressor encoded by gro, which in turn enables the transcription of Wnt targets. [Date last reviewed: 2018-09-13]
FBgn0002440	l(3)mbn	lethal (3) malignant blood neoplasm	lethal (3) malignant blood neoplasm (l(3)mbn) is a tumor suppressor gene with mutants showing abnormal proliferation of blood cells, differentiation of lamellocytes and melanotic nodule formation in the larva. [Date last reviewed: 2019-09-26]
FBgn0002441	l(3)mbt	lethal (3) malignant brain tumor	lethal (3) malignant brain tumor (l(3)mbt) encodes a tumor suppressor protein regulating proliferation in the brain, particularly the optic lobes. The proposed functions of the product of l(3)mbt include histone compaction, establishment of chromatin insulators, regulation of the Hippo pathway and repression of the germ line program in somatic cells. [Date last reviewed: 2019-09-26]
FBgn0002466	sti	sticky	sticky (sti) encodes a member of the AGC family of kinases that functions to regulate both actin-myosin-mediated cytokinesis and epigenetic gene silencing. [Date last reviewed: 2019-03-14]
FBgn0002521	pho	pleiohomeotic	pleiohomeotic (pho) encodes a zinc-finger protein that binds to Polycomb response elements and is required for recruitment of Polycomb group protein complexes to chromatin. It is primarily a transcriptional repressor. [Date last reviewed: 2019-03-14]
FBgn0002524	lace	lace	lace (lace) encodes a serine C-palmitoyltransferase involved in sphingolipid biosynthesis. [Date last reviewed: 2019-09-19]
FBgn0002525	Lam	Lamin	NA
FBgn0002526	LanA	Laminin A	NA
FBgn0002542	lds	lodestar	lodestar (lds) encodes a protein that belongs to the helicase-related family and is part of the spindle assembly checkpoint engaged in the maintenance of chromosome/genome stability. It is required to load cohesin complexes onto the chromosomes during the embryonic cleavage mitoses. Absence of lds leads to frequent chromosome loss and death of cells and embryos. [Date last reviewed: 2019-03-14]
FBgn0002543	robo2	roundabout 2	roundabout 2 (robo2) encodes a member of the Robo receptor family that responds to the ligand encoded by sli as a repulsive cue in axons, dendrites, muscles, trachea and heart development. It can also inhibit robo1 signaling, likely explaining why the product of robo2 can appear to be an attractive receptor in certain contexts. [Date last reviewed: 2019-03-21]
FBgn0002552	lin	lines	lines (lin) encodes a nuclear protein involved in developmental patterning and cell fate specification. The Odd-skipped family protein encoded by bowl binds to and destabilizes the product of lin in the nucleus. Converserly the Odd family protein encoded by drm stabilizes the product of bowl in the nucleus by outcompeting the binding of the product of lin to the product of bowl and localizing the product of lin to the cytoplasm. [Date last reviewed: 2019-03-14]
FBgn0002566	lt	light	light (lt) encodes a cellular-protein trafficking protein that forms part of the homotypic fusion and vacuolar protein sorting (HOPS) and class C core vacuole/endosome tethering (CORVET) complexes. It is required for fusion of autophagosomes with lysosomes, endocytic down-regulation of Notch signaling, and eye pigment biogenesis. [Date last reviewed: 2019-03-14]
FBgn0002567	Rab32	Rab32	Rab32 (Rab32) encodes a small GTPase that contributes to vesicle trafficking regulation. It is involved in eye development, autophagy and lipid storage. [Date last reviewed: 2019-09-26]
FBgn0002576	lz	lozenge	lozenge (lz) encodes an alpha-subunit of the transcription factor complex core binding factor, which is involved in transcription regulation. It plays an important role during eye development contributing to programmed cell death, eye morphogenesis, eye cone cell differentiation and R7 cell development. It contributes to hemopoiesis and wound healing. [Date last reviewed: 2019-03-14]
FBgn0002577	m	miniature	miniature (m) encodes a protein that belongs to the ZP-domain proteins family known as extracellular modular proteins. These proteins are secreted and anchored to the membrane or released into the extracellular space to form specialized extracellular matrices. [Date last reviewed: 2019-03-14]
FBgn0002579	RpL36	Ribosomal protein L36	NA
FBgn0002590	RpS5a	Ribosomal protein S5a	Ribosomal protein S5a (RpS5a) encodes a structural constituent of ribosomes. [Date last reviewed: 2019-07-11]
FBgn0002593	RpLP1	Ribosomal protein LP1	Ribosomal protein LP1 (RpLP1) encodes a member of the cytoplasmic large ribosomal protein family. [Date last reviewed: 2018-09-20]
FBgn0002609	E(spl)m3-HLH	Enhancer of split m3, helix-loop-helix	Enhancer of split m3, helix-loop-helix (E(spl)m3-HLH) is a member the enhancer of split gene (E(spl)) complex. E(spl)m3-HLH encodes a transcriptional repressor executing Notch-mediated cellular differentiation. [Date last reviewed: 2019-09-26]
FBgn0002622	RpS3	Ribosomal protein S3	Ribosomal protein S3 (RpS3) encodes a component of the small subunit of cytoplasmic ribosomes, which translate mRNAs encoded by the nuclear genome. RpS3 is haploinsufficient - heterozygous mutants display the 'Minute' phenotype, characterized by a slower developmental rate and small adult bristles. The product of RpS3 also contains a DNA lyase activity and functions in DNA repair. [Date last reviewed: 2019-03-14]
FBgn0002626	RpL32	Ribosomal protein L32	NA
FBgn0002638	Rcc1	Regulator of chromosome condensation 1	Regulator of chromosome condensation 1 (Rcc1) encodes the guanine-nucleotide exchange factor for the product of Ran. It promotes the nucleo-cytoplasmic shuttling of specific proteins and regulates chromatin condensation. The roles of Rcc1 product include cell proliferation, cell survival, apoptosis, epigenetic regulation, and neuronal specification. [Date last reviewed: 2019-03-14]
FBgn0002641	mal	maroon-like	NA
FBgn0002643	mam	mastermind	mastermind (mam) encodes a transcriptional coactivator that functions in the Notch signaling pathway. It regulates gene expression by interacting with the intracellular domain of the product of N, which is produced upon receptor activation. [Date last reviewed: 2019-03-14]
FBgn0002645	Map205	Microtubule-associated protein 205	Microtubule-associated protein 205 (Map205) encodes a protein that binds and stabilizes microtubules. It also binds, inhibits and stabilizes the product of polo on microtubules during interphase. [Date last reviewed: 2019-03-14]
FBgn0002673	twe	twine	twine (twe) encodes a putative tyrosine phosphatase. It regulates the meiotic cell cycle and contributes to spermatogenesis. [Date last reviewed: 2019-03-14]
FBgn0002707	mei-9	meiotic 9	meiotic 9 (mei-9) encodes the catalytic subunit of the Mei-9-Ercc1 structure-selective endonuclease that functions in nucleotide excision repair. The products of mei-9 and Ercc1 interact with the product of mus312 to generate meiotic crossovers. [Date last reviewed: 2019-03-14]
FBgn0002715	mei-S332	meiotic from via Salaria 332	meiotic from via Salaria 332 (mei-S332) encodes the founding member of the Shugoshin protein family and is required for retention of centromere cohesion in both male and female meiosis I. [Date last reviewed: 2019-03-14]
FBgn0002716	mei-W68	meiotic W68	meiotic W68 (mei-W68) encodes a protein thought to form a dimer with the TopoVIA subunit encoded by mei-P22 and is required for the formation of double strand breaks during meiosis. [Date last reviewed: 2019-03-14]
FBgn0002719	Men	Malic enzyme	Malic enzyme (Men) encodes a dehydrogenase that catalyzes the oxidation of malate to pyruvate, with the concomitant reduction of NADP[+] to NADPH. It functions, along with the products of Idh, Zw, and Pgd, in a small network of NADP reducing enzymes. [Date last reviewed: 2019-03-14]
FBgn0002723	Met	Methoprene-tolerant	Methoprene-tolerant (Met) encodes bHLH-PAS domain transcription factor paralogous to gce. It is a receptor for the sesquiterpenoid juvenile hormone. [Date last reviewed: 2019-03-14]
FBgn0002733	E(spl)mbeta-HLH	Enhancer of split mbeta, helix-loop-helix	NA
FBgn0002736	mago	mago nashi	mago nashi (mago) encodes a protein that is part of the exon junction complex, which is required for post-transcriptional processes such as pre-mRNA splicing, RNA localization and nonsense-mediated decay. It is involved in germline development, germplasm assembly and photoreceptor differentiation. [Date last reviewed: 2019-03-14]
FBgn0002773	Mlc2	Myosin light chain 2	Myosin light chain 2 (Mlc2) encodes a subunit of the myosin complex involved in myofibril assembly. It contributes to different flight-related processes including wing beat frequency, and indirect flight muscle contraction. [Date last reviewed: 2019-07-11]
FBgn0002774	mle	maleless	maleless (mle) encodes a helicase and a member of the Male-Specific-Lethal dosage compensation complex, which increases male X chromosome transcription approximately two-fold. mle homozygous mutant males die as larvae, while females are viable. [Date last reviewed: 2019-03-14]
FBgn0002775	msl-3	male-specific lethal 3	male-specific lethal 3 (msl-3) encodes a chromodomain protein, reported to interact with H3K36me3, H4K20me1 and DNA. It is a member of the Male-Specific-Lethal dosage compensation complex, which increases male X chromosome transcription approximately two-fold. Homozygous mutant males die as larvae, while females are viable. [Date last reviewed: 2019-03-14]
FBgn0002778	mnd	minidiscs	minidiscs (mnd) encodes the putative amino acid/polyamine transporter involved in leucine import. It is expressed in the larval fat body and is required for the differentiation of the wing imaginal disc cells. [Date last reviewed: 2019-03-14]
FBgn0002780	mod	modulo	modulo (mod) encodes a nucleolar protein that is required for growth of proliferative cells through its association with the proto-oncogene Myc. The mod protein is essential for transcription of spermatid-differentiation genes and for high expression of meiotic arrest genes. The product of mod is phosphorylated, which in turn regulates its localization. [Date last reviewed: 2018-09-20]
FBgn0002781	mod(mdg4)	modifier of mdg4	modifier of mdg4 (mod(mdg4)) encodes a nuclear protein that specifically interacts with various DNA binding proteins. It is involved in processes including chromosome condensation and segregation, regulation of transcription and enhancer blocking. [Date last reviewed: 2019-09-26]
FBgn0002783	mor	moira	moira (mor) encodes a member of the trithorax group of homeotic gene regulators. The product of mor is a chromatin remodeling protein and functions as the Swi3 component of the Brahma complex. [Date last reviewed: 2018-09-20]
FBgn0002787	Rpn8	Regulatory particle non-ATPase 8	NA
FBgn0002791	mr	morula	morula (mr) encodes the APC2 subunit of the anaphase promoting complex (APC). mr strong alleles produce lethality, metaphase arrest and neuroblast polyploidy. mr weak alleles result in female sterility, affecting the endocycle in the nurse cells, as well as metaphase arrest in early embryonic mitoses. [Date last reviewed: 2019-03-14]
FBgn0002868	MtnA	Metallothionein A	Metallothionein A (MtnA) encodes a member of the Metallothionein family whose transcript level is higher than that of the other four Drosophila metallothioneins. Transcription is strongly induced by copper and cadmium ions and this induction depends on the transcription factor encoded by MTF-1. [Date last reviewed: 2019-03-14]
FBgn0002872	mu2	mutator 2	mutator 2 (mu2) encodes an androgen receptor co-activator involved in double-strand break repair and regulation of chromatin organization. [Date last reviewed: 2019-03-14]
FBgn0002873	mud	mushroom body defect	mushroom body defect (mud) encodes regulates spindle orientation via interactions with the dynein complex. [Date last reviewed: 2019-03-14]
FBgn0002878	mus101	mutagen-sensitive 101	mutagen-sensitive 101 (mus101) encodes a protein involved in the DNA replication checkpoint during mitosis. [Date last reviewed: 2019-09-19]
FBgn0002891	PolZ1	DNA polymerase zeta subunit 1	DNA polymerase zeta subunit 1 (PolZ1) encodes a DNA polymerase zeta catalytic subunit. It acts as a translesion polymerase during the bypass of DNA damage and has roles in DNA double-strand break and interstrand crosslink repair. [Date last reviewed: 2019-09-26]
FBgn0002899	mus301	mutagen-sensitive 301	mutagen-sensitive 301 (mus301) encodes a member of the Mus308 subfamily of ATP-dependent helicases. It is involved in the repair of double-strand DNA breaks during recombination and in somatic cells, and in chromosome segregation. It contributes to dorsal-ventral patterning during oogenesis and posterior oocyte positioning. [Date last reviewed: 2019-03-14]
FBgn0002901	mus304	mutagen-sensitive 304	NA
FBgn0002905	PolQ	DNA polymerase theta	DNA polymerase theta (PolQ) encodes DNA polymerase theta, a dual-domain protein with helicase-like and translesion polymerase domains. It contributes to repair/tolerance of DNA interstrand crosslinks and alternative-end joining repair of DNA double-strand breaks. [Date last reviewed: 2019-10-03]
FBgn0002906	Blm	Bloom syndrome helicase	Bloom syndrome helicase (Blm) encodes a protein that plays important roles in repairing replication fork damage and double-strand breaks. It promotes repair through non-crossover mechanisms, though it also has roles in meiotic recombination. [Date last reviewed: 2019-03-07]
FBgn0002914	Myb	Myb oncogene-like	Myb oncogene-like (Myb) encodes a transcription factor that activates the transcription of genes involved in the G2/M phases of the cell cycle. This activation occurs by inhibition of the highly conseved MuvB multi-protein repressor complex. [Date last reviewed: 2019-03-14]
FBgn0002917	na	narrow abdomen	narrow abdomen (na) encodes an ion channel involved in circadian locomotor rhythms and touch perception. [Date last reviewed: 2019-09-26]
FBgn0002921	Atpalpha	Na pump alpha subunit	Na pump α subunit (Atpα) encodes an integral membrane cation antiporter protein that utilizes ATP to shuttle Na[+] and K[+] across the plasma membrane to maintain ion homeostasis. [Date last reviewed: 2019-03-07]
FBgn0002924	ncd	non-claret disjunctional	non-claret disjunctional (ncd) encodes a minus-end-directed kinesin microtubule motor protein and the sole member of the kinesin-14 motor family. It is required for spindle assembly in oocytes and chromosome attachment to spindles in early embryos. [Date last reviewed: 2019-03-14]
FBgn0002926	ndl	nudel	nudel (ndl) encodes a multi-functional protein with serine protease activity. It is required for both eggshell biogenesis and embryonic dorsoventral patterning. [Date last reviewed: 2019-03-14]
FBgn0002931	net	net	net (net) encodes a basic helix-loop-helix protein that probably acts as a transcriptional repressor. During wing vein formation it is expressed in all interveins territories and antagonises the activity of the product of Egfr. [Date last reviewed: 2019-03-14]
FBgn0002932	neur	neuralized	neuralized (neur) encodes an E3 ubiquitin ligase of the RING family. It is part of the Notch signaling pathway, where it is thought to contribute to the endocytosis-dependent activation of the ligand. It also has Notch-independent functions in epithelial morphogenesis. [Date last reviewed: 2019-03-14]
FBgn0002945	nkd	naked cuticle	NA
FBgn0002948	nod	no distributive disjunction	no distributive disjunction (nod) encodes a kinesin-like protein that is important for nonexchange chromosome biology. The nod product is necessary for chromosome segregation during meiosis and for proper chromosome alignment along the meiotic spindle. [Date last reviewed: 2019-03-21]
FBgn0002973	numb	numb	numb (numb) encodes a membrane-associated inhibitor of Notch signaling. It controls neuroblast and sense organ precursor asymmetric division. It is asymmetrically localized during mitosis and segregates exclusively to one of two daughter cells. [Date last reviewed: 2019-03-14]
FBgn0002989	okr	okra	okra (okr) encodes a helicase involved in homologous DNA repair. It functions in meiotic recombination. [Date last reviewed: 2019-03-14]
FBgn0003008	or	orange	orange (or) encodes an AP-3 adaptor complex component involved in ommochrome biosynthesis. [Date last reviewed: 2019-07-11]
FBgn0003016	osp	outspread	outspread (osp) encodes a protein that contributes to embryonic crystal cell formation and the proper morphogenesis of the adult wing. [Date last reviewed: 2019-03-14]
FBgn0003041	pbl	pebble	pebble (pbl) encodes a Rho guanine nucleotide exchange factor that contributes to multiple processes involving actin cytoskeleton reorganization, including cytokinesis, axogenesis and wound healing as well as cell shape regulation and cell migration during gastrulation. [Date last reviewed: 2019-06-13]
FBgn0003042	Pc	Polycomb	Polycomb (Pc) encodes a chromatin binding protein that interacts with histone H3K27me3. It is involved in epigenetic silencing and its target genes are predominantly transcription factors or receptors that control cell fate and most developmental decisions. [Date last reviewed: 2019-03-14]
FBgn0003044	Pcl	Polycomblike	Polycomblike (Pcl) encodes a protein required for taste response to sugar. It regulates the expression of Ptx1, cad, nub, scro and GATAe in response to diet. The distribution of Pcl bound to chromatin in the sweet taste cells is nutrient dependent. [Date last reviewed: 2021-01-21]
FBgn0003048	pcx	pecanex	NA
FBgn0003053	peb	pebbled	pebbled (peb) encodes a protein that acts as a tissue-specific transcriptional attenuator. It contributes to embryonic morphogenesis and development of ovary, retina and respiratory system. [Date last reviewed: 2019-03-14]
FBgn0003062	Fib	Fibrillarin	Fibrillarin (Fib) encodes an rRNA 2'-O-methyltransferase required for pre-rRNA processing. [Date last reviewed: 2019-03-07]
FBgn0003067	Pepck1	Phosphoenolpyruvate carboxykinase 1	Phosphoenolpyruvate carboxykinase 1 (Pepck1) encodes an enzyme that converts oxaloacetate into phosphoenolpyruvate. It catalyzes the first committed step in gluconeogenesis and thus plays an essential role in glucose metabolism. [Date last reviewed: 2019-03-14]
FBgn0003068	per	period	NA
FBgn0003071	Pfk	Phosphofructokinase	NA
FBgn0003074	Pgi	Phosphoglucose isomerase	Phosphoglucose isomerase (Pgi) encodes an enzyme involved in glucose homeostasis. [Date last reviewed: 2019-09-12]
FBgn0003076	Pgm1	Phosphoglucose mutase 1	NA
FBgn0003079	Raf	Raf oncogene	Raf oncogene (Raf) encodes a serine-threonine protein kinase that acts downstream of the product of ras. It activates the MEK/ERK pathway to regulate cell proliferation, differentiation and survival downstream of receptor tyrosine kinases such as those encoded by tor, Egfr, and sev. [Date last reviewed: 2019-03-14]
FBgn0003082	phr	photorepair	photorepair (phr) encodes a DNA photolyase apoenzyme that repairs UV-induced DNA damage using FAD as a cofactor and blue light as a co-substrate. [Date last reviewed: 2019-03-21]
FBgn0003087	pim	pimples	pimples (pim) encodes the Drosophila Securin homolog. Securins bind to the endoprotease Separase. In some species including Drosophila, this binding appears to promote proper folding of Separase. In addition, securin binding inhibits separase endoprotease activity in all species via an inhibitory pseudosubstrate region. [Date last reviewed: 2019-03-14]
FBgn0003093	Pkc98E	Protein C kinase 98E	Protein C kinase 98E (Pkc98E) encodes a serine-threonine protein kinase activated by calcium, membrane translocation and lipids (such as diacylglycerol and phorbol ester). Pkc98E product controls cytoskeleton by negatively regulating the F-actin bundling protein encoded by sn. [Date last reviewed: 2018-09-20]
FBgn0003116	pn	prune	prune (pn) encodes a phosphoesterase that localizes to the mitochondrial matrix. It hydrolyzes cAMP and negatively regulates mitochondrial cAMP signaling. It is involved in mtDNA maintenance and eye pigment biosynthesis. [Date last reviewed: 2019-03-14]
FBgn0003117	pnr	pannier	pannier (pnr) encodes a transcription factor that acts as an activator of proneural achaete-scute complex genes. Its roles include dorsal cell fate determination, nervous system development and lymph gland development. [Date last reviewed: 2019-03-14]
FBgn0003118	pnt	pointed	NA
FBgn0003124	polo	polo	NA
FBgn0003134	Pp1alpha-96A	Protein phosphatase 1alpha at 96A	Protein phosphatase 1α at 96A (Pp1α-96A) encodes a phosphatase involved in the regulation of Hedgehog and Wnt signaling pathways. [Date last reviewed: 2019-09-12]
FBgn0003137	Ppn	Papilin	NA
FBgn0003139	PpV	Protein phosphatase V	Protein phosphatase V (PpV) encodes the catalytic subunit of the protein phosphatase 6 (PP6), which negatively regulates JNK and AMPK signaling. PpV product is essential for lipid homeostasis and Ras-induced tumorigenesis. [Date last reviewed: 2018-09-20]
FBgn0003141	pr	purple	NA
FBgn0003159	CG2841	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0003162	Pu	Punch	NA
FBgn0003165	pum	pumilio	pumilio (pum) encodes a founding member of the PUF family of RNA binding proteins. It is an essential factor in the translational regulation of hb mRNA in the early embryo. pum product also contributes to multiple processes, including germline stem cell identity maintenance, primordial germ cell proliferation and migration, synaptic plasticity, as well as learning and memory. [Date last reviewed: 2018-09-20]
FBgn0003169	put	punt	punt (put) encodes a transforming growth factor beta type II receptor that functions in both Dpp/BMP and Activin signaling. Pathway specificity in signaling output is determined by which type I receptor (Dpp/BMP or Activin one) is engaged in the complex with the product of put. [Date last reviewed: 2019-03-14]
FBgn0003175	px	plexus	plexus (px) encodes a ubiquitously expressed nuclear matrix protein required to restrict excess wing vein development by repressing transcription of the pro-vein gene rho. [Date last reviewed: 2019-03-14]
FBgn0003189	r	rudimentary	rudimentary (r) encodes the CAD protein that catalyzes the initial steps of de novo pyrimidine biosynthesis. r depletion results in wing malformations and pyrimidine auxotrophy. [Date last reviewed: 2019-03-14]
FBgn0003204	ras	raspberry	NA
FBgn0003205	Ras85D	Ras oncogene at 85D	Ras oncogene at 85D (Ras85D) encodes a protein that acts downstream of several cell signals, most notably from Receptor Tyrosine Kinases, to regulate tissue growth and development. When abnormally activated it can direct developmental defects and tissue hyperplasia, mimicking aspects of human disease including Rasopathies and cancer, respectively. [Date last reviewed: 2019-03-14]
FBgn0003206	Ras64B	Ras oncogene at 64B	NA
FBgn0003209	raw	raw	raw (raw) encodes a membrane protein involved in dendrite patterning and the subcellular localization of JNK signalling components. [Date last reviewed: 2019-09-26]
FBgn0003210	rb	ruby	ruby (rb) encodes the beta3-adaptin subunit of the Adaptor protein-3 (AP-3) complex involved in biogenesis of lysosome-related organelles. It is required for regulation of lipid storage, eye pigment biogenesis and the processing of the receptor encoded by N. [Date last reviewed: 2019-03-14]
FBgn0003218	rdgB	retinal degeneration B	retinal degeneration B (rdgB) encodes a member of the Class IIA Phosphatidylinositol transfer protein (PITP) family. It supports multiple biochemical functions involving lipid transfer during G-protein coupled phospholipase C activation. [Date last reviewed: 2019-03-14]
FBgn0003227	rec	recombination-defective	recombination-defective (rec) interacts with other Mini-Chromosome Maintenance (MCM)-related proteins (encoded by mei-217 and mei-218) to make meiotic crossovers. [Date last reviewed: 2019-03-21]
FBgn0003231	ref(2)P	refractory to sigma P	NA
FBgn0003256	rl	rolled	rolled (rl) encodes the mitogen activated protein (MAP) kinase, core component of the RAS/MAPK pathway. It is inactivated by the phosphatases encoded by PTP-ER and Mkp3. It phosphorylates a diverse set of downstream cytoplasmic and nuclear effectors, which impact cell fate decisions in a wide array of tissues. [Date last reviewed: 2019-03-14]
FBgn0003257	r-l	rudimentary-like	rudimentary-like (r-l) encodes an enzyme involved in the novo pyrimidine biosynthesis. [Date last reviewed: 2019-07-11]
FBgn0003261	Rm62	Rm62	NA
FBgn0003268	rod	rough deal	rough deal (rod) encodes the major subunit of the Rod-Zw10-Zwilch (RZZ) complex. RZZ is an essential component of the outer kinetochore during mitosis. RZZ helps monitor and correct kinetochore-microtubule attachments during prometaphase, and consequently it regulates mitotic progression. [Date last reviewed: 2019-03-14]
FBgn0003274	RpLP2	Ribosomal protein LP2	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0003275	Polr2F	RNA polymerase II, I and III subunit F	RNA polymerase II, I and III subunit F (Polr2F) encodes a shared subunit of RNA polymerases I, II, and III. [Date last reviewed: 2018-09-20]
FBgn0003277	Polr2A	RNA polymerase II subunit A	NA
FBgn0003278	Polr1B	RNA polymerase I subunit B	NA
FBgn0003279	RpL4	Ribosomal protein L4	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0003301	rut	rutabaga	rutabaga (rut) encodes a membrane-bound Ca[2+]/calmodulin-activated adenylyl cyclase that is responsible for synthesis of cAMP. It plays a key role in regulating behavioral, neuroanatomical, and electrophysiological plasticity. [Date last reviewed: 2019-03-14]
FBgn0003302	rux	roughex	NA
FBgn0003308	ry	rosy	NA
FBgn0003310	S	Star	Star (S) encodes a type II transmembrane protein that facilitates trafficking of transmembrane Egfr ligands from the endoplasmic reticulum to the late secretory compartment. It is involved in growth regulation, cell survival and developmental patterning. [Date last reviewed: 2019-03-14]
FBgn0003317	sax	saxophone	saxophone (sax) encodes a type I BMP receptor. Together with the BMP receptors encoded by tkv and put, it transduces signaling of the BMP ligands encoded by dpp, gbb and scw, in a wide variety of developmental processes including embryonic and imaginal disc patterning. [Date last reviewed: 2019-03-14]
FBgn0003321	sbr	small bristles	NA
FBgn0003330	Sce	Sex combs extra	NA
FBgn0003334	Scm	Sex comb on midleg	NA
FBgn0003345	sd	scalloped	scalloped (sd) encodes a DNA binding protein of the TEAD class. It requires co-factor proteins ,such as the products of vg and yki, to act as a transcription factor, and is modified by Hippo and Wingless signalling. It is involved in wing and neuronal specification. [Date last reviewed: 2019-03-14]
FBgn0003346	RanGAP	Ran GTPase activating protein	NA
FBgn0003353	sei	seizure	seizure (sei) encodes a protein involved in sound perception. [Date last reviewed: 2019-08-01]
FBgn0003360	sesB	stress-sensitive B	NA
FBgn0003371	sgg	shaggy	shaggy (sgg) encodes a glycogen synthase kinase 3, and a key component of the β-catenin destruction complex. It functions in the canonical Wnt cascade. [Date last reviewed: 2019-03-14]
FBgn0003390	shf	shifted	shifted (shf) encodes a secreted protein that positively modulates Hedgehog signaling. It controls the diffusion of the lipid-modified protein encoded by hh by stabilizing its interaction with the heparan sulfate proteoglycans. [Date last reviewed: 2019-03-14]
FBgn0003391	shg	shotgun	NA
FBgn0003392	shi	shibire	NA
FBgn0003396	shn	schnurri	schnurri (shn) encodes a zinc finger C2H2 transcription factor involved in Dpp signaling. It contributes to multiple processes including ectoderm and midgut development, wing disc patterning and morphogenesis of Malpighian tubules and dendrites. [Date last reviewed: 2019-06-13]
FBgn0003401	shu	shutdown	shutdown (shu) encodes an immunophilin cochaperone that collaborates with Hsp90 during piRNA biogenesis and is essential for normal function of germline stem cells. [Date last reviewed: 2019-03-14]
FBgn0003410	sina	seven in absentia	NA
FBgn0003415	skd	skuld	skuld (skd) encodes a subunit of the kinase module of the mediator complex. It is not required for all the transcriptional functions of mediator, but links it to a set of transcription factors that are involved in developmental signaling. [Date last reviewed: 2019-03-14]
FBgn0003416	sl	small wing	small wing (sl) encodes a phosphatidylinositol-specific phospholiase type C that is required as a general modulator for growth downstream of the insulin pathway, and interacts with the Ras-MAPK pathway. [Date last reviewed: 2019-03-14]
FBgn0003423	slgA	sluggish A	NA
FBgn0003435	sm	smooth	smooth (sm) encodes an RNA binding, heterogeneous nuclear ribonucleoprotein involved in axon guidance, mRNA processing, chemosensation, determination of lifespan and feeding behavior. [Date last reviewed: 2019-03-14]
FBgn0003444	smo	smoothened	smoothened (smo) encodes a critical component of the Hedgehog signaling pathway. It is regulated by phosphorylation, dimerization, and cell-surface accumulation upon Hedgehog stimulation. The product of smo is also regulated by ubiquitin and other small molecules such as phospholipids. [Date last reviewed: 2019-03-14]
FBgn0003447	sn	singed	singed (sn) encodes a member of the fascin family of actin-binding proteins. Fascin proteins organize F-actin into parallel bundles, and are required for the formation of actin-based cellular protrusions. The bundling activity of the product of sn is regulated by phosphorylation. [Date last reviewed: 2019-03-14]
FBgn0003449	snf	sans fille	sans fille (snf) encodes a protein component of U1 and U2 small nuclear ribonucleoproteins (snRNPs). U1 and U2 snRNPs combine with other snRNPs on the pre-mRNA to assemble a spliceosome. It contributes to alternative splicing regulation. [Date last reviewed: 2019-03-14]
FBgn0003459	stwl	stonewall	stonewall (stwl) encodes a protein that is associated with heterochromatin and modifies levels of trimethylated H3K27 and H3K9. stwl product is required for maintenance of female germline stem cells and for survival of genotoxic stress induced by DNA replication inhibition. [Date last reviewed: 2018-09-20]
FBgn0003462	Sod1	Superoxide dismutase 1	NA
FBgn0003463	sog	short gastrulation	short gastrulation (sog) encodes a secreted BMP antagonist that is expressed in the embryonic ventral neuroectoderm. sog product promotes neural development by preventing dorsally produced dpp from diffusing into the neuroectoderm and suppressing expression of neural genes. sog protein also diffuses dorsally where it helps establish a BMP activity gradient essential for partitioning that domain into cells giving rise to the dorsal epidermis versus amnioserosa. [Date last reviewed: 2018-09-20]
FBgn0003464	sol	small optic lobes	NA
FBgn0003475	spir	spire	spire (spir) encodes a de novo WH2 domain-containing actin nucleation factor that polymerizes linear actin filaments, as well as bundles and/or crosslinks actin and microtubules. It is a downstream effector of the product of Rho1 and is involved in many cytoskeleton related developmental processes, including ooplasmic streaming, nurse cell architecture, and endocytosis. [Date last reviewed: 2019-03-14]
FBgn0003479	spn-A	spindle A	spindle A (spn-A) encodes a protein that forms a filament on single-stranded DNA, does a homology search of double-stranded DNA, and catalyzes strand exchange, swapping the single-strand DNA in and displacing the partner of the complementary strand. [Date last reviewed: 2019-03-14]
FBgn0003480	spn-B	spindle B	spindle B (spn-B) encodes a member of the recA family. It is involved in double strand break repair in mitosis and meiosis. [Date last reviewed: 2019-03-14]
FBgn0003483	spn-E	spindle E	NA
FBgn0003495	spz	spatzle	spatzle (spz) encodes a secreted protein which, after cleavage by an extracellular serine protease (encoded by ea or SPE), can induce the dimerization of the product of Tl, and the subsequent activation of the Toll pathway. It contributes to function of the Toll signaling cascade, which plays a key role in various developmental and immune processes, notably embryonic dorso-ventral patterning and regulation of antimicrobial peptides. [Date last reviewed: 2019-06-06]
FBgn0003499	sr	stripe	stripe (sr) encodes a transcription factor that induces the fate of tendon cells in the embryo as well as in the adult fly. It works upstream of tendon specific genes including Tsp, slow and Lrt. [Date last reviewed: 2019-03-14]
FBgn0003502	Btk29A	Btk family kinase at 29A	Btk family kinase at 29A (Btk29A) encodes a non-receptor tyrosine kinase with diverse roles including cellularization, morphogenesis, patterning and germ cell proliferation. [Date last reviewed: 2019-03-07]
FBgn0003507	srp	serpent	serpent (srp) encodes an important transcription factor for the proper development of mesodermal derivatives such as fat body, hemocytes and limph gland. It contributes to endoderm development, hemopoiesis and glucose metabolism. [Date last reviewed: 2019-03-14]
FBgn0003510	Sry-alpha	Serendipity alpha	NA
FBgn0003511	Sry-beta	Serendipity beta	NA
FBgn0003512	Sry-delta	Serendipity delta	NA
FBgn0003514	sqh	spaghetti squash	spaghetti squash (sqh) encodes the regulatory light chain of the nonmuscle type 2 myosin. Its phosphorylation through the Rho-Rho Kinase pathway is predicted to activate myosin motor activity. The product of sqh and myosin function in cellular processes such as cytokinesis, and also contribute to tissue morphogenesis. [Date last reviewed: 2019-03-14]
FBgn0003517	sta	stubarista	NA
FBgn0003520	stau	staufen	staufen (stau) encodes a double-stranded RNA binding protein involved in mRNA localization. It contributes to anterior and posterior patterning, nervous system development and long term memory. [Date last reviewed: 2019-03-14]
FBgn0003525	stg	string	NA
FBgn0003545	sub	subito	subito (sub) encodes a kinesin-6 homolog. Kinesin-6 proteins are known to bundle antiparallel microtubules. The product of sub is required for cytokinesis in mitosis and spindle organization and chromosome segregation in female meiosis. [Date last reviewed: 2019-03-14]
FBgn0003557	Su(dx)	Suppressor of deltex	NA
FBgn0003559	su(f)	suppressor of forked	suppressor of forked (su(f)) is an essential gene that encodes a protein involved in mRNA 3'-end processing (the nuclear cleavage/polyadenylation reaction) and alternative poly(A) site utilization. su(f) product accumulates in dividing cells where it is required for mitosis progression. [Date last reviewed: 2019-09-26]
FBgn0003567	su(Hw)	suppressor of Hairy wing	NA
FBgn0003575	su(sable)	suppressor of sable	NA
FBgn0003598	Su(var)3-7	Suppressor of variegation 3-7	Suppressor of variegation 3-7 (Su(var)3-7) encodes a protein associated with heterochromatin. Increasing the amount of the product of Su(var)3-7 triggers heterochromatin expansion and epigenetic gene silencing. [Date last reviewed: 2019-09-26]
FBgn0003607	Su(var)205	Suppressor of variegation 205	NA
FBgn0003612	Su(var)2-10	Suppressor of variegation 2-10	Suppressor of variegation 2-10 (Su(var)2-10) encodes a member of the PIAS protein family that regulates chromosome structure and function. As a JAK/STAT pathway regulator, it contributes to eye formation and eye determination. [Date last reviewed: 2019-09-26]
FBgn0003638	su(w[a])	suppressor of white-apricot	NA
FBgn0003654	sw	short wing	short wing (sw) encodes the non-catalytic intermediate chain subunit of the cytoplasmic dynein motor complex. It contributes to wing development, eye development, oocyte development and polarity, mitotic cell division, and neuronal transport and neurogenesis. [Date last reviewed: 2019-03-14]
FBgn0003655	swa	swallow	NA
FBgn0003656	sws	swiss cheese	swiss cheese (sws) encodes a transmembrane protein that hydrolyzes phosphatidylcholine and binds to and inhibits the C3 catalytic subunit of protein kinase A. Its loss leads to neuronal and glial degeneration and apoptotic cell death. [Date last reviewed: 2019-03-14]
FBgn0003660	Syb	Synaptobrevin	NA
FBgn0003676	CCT1	Chaperonin containing TCP1 subunit 1	NA
FBgn0003687	Tbp	TATA binding protein	TATA binding protein (Tbp) encodes a basal transcription factor required at most RNA Pol I and Pol II-transcribed genes. Traditionally thought to be recruited only to TATA box containing promoters, recent work shows that promoters with very weak TATA box consensus sequences also recruit the product of Tbp as a part of the multisubunit TFIID basal transcription factor or via the SAGA histone acetyltransferase complex. [Date last reviewed: 2019-03-14]
FBgn0003701	thr	three rows	three rows (thr) encodes a protein that, together with the product of Sse, forms the endoprotease separase complex, which cleaves a subunit of the cohesin complex, thereby allowing separation of the sister chromatids. [Date last reviewed: 2019-03-14]
FBgn0003714	tko	technical knockout	technical knockout (tko) encodes the mitochondrial ribosomal protein S12. It is involved in the response to hypoxia and mechanosensory and courtship behaviors. [Date last reviewed: 2018-09-20]
FBgn0003716	tkv	thickveins	thickveins (tkv) encodes a transforming growth factor beta type I receptor. Together with the product of put, it functions as a receptor of the product of dpp and therefore contributes to the BMP signaling pathway. [Date last reviewed: 2019-06-13]
FBgn0003721	Tm1	Tropomyosin 1	NA
FBgn0003731	Egfr	Epidermal growth factor receptor	Epidermal growth factor receptor (Egfr) encodes the transmembrane tyrosine kinase receptor for signaling ligands (encoded by grk, spi, vn, and Krn) in the TGFα family, which utilises the intracellular MAP kinase pathway. The product of Egfr contributes to growth regulation, cell survival and developmental patterning. [Date last reviewed: 2019-06-06]
FBgn0003741	tra	transformer	NA
FBgn0003742	tra2	transformer 2	transformer 2 (tra2) is a sex-determining gene that encodes a pre-mRNA binding protein. It regulates the alternative splicing of several mRNAs including those from key regulators of sexual differentiation, dsx and fru, and Taf1, which encodes a TFIID component. [Date last reviewed: 2019-03-14]
FBgn0003744	trc	tricornered	tricornered (trc) encodes a nuclear Dbf2-related kinase whose mutations lead to mulitpled hairs, split and multipled arista laterals and to defects in dendritic tiling. [Date last reviewed: 2019-03-14]
FBgn0003748	Treh	Trehalase	Trehalase (Treh) encodes an enzyme that hydrolyzes the the disaccharide trehalose to two molecules of glucose in either the cytoplasm or the extracellular space. [Date last reviewed: 2018-09-20]
FBgn0003862	trx	trithorax	trithorax (trx) encodes a chromatin-modifying enzyme involved in gene regulation. It methylates the histone encoded by His3 on Lys-4, promoting its further acetylation. This activity antagonises the epigenetic silencing by Polycomb group proteins. It contributes to axon guidance, eye development and germ cell migration. [Date last reviewed: 2019-03-14]
FBgn0003866	tsh	teashirt	NA
FBgn0003870	ttk	tramtrack	NA
FBgn0003882	tub	tube	tube (tub) encodes an adaptor protein, which functions downstream of the product of Myd88 in the Toll pathway. Toll pathway is a signaling cascade that plays a key role in various developmental and immune processes, notably embryonic dorsoventral patterning and regulation of antimicrobial peptides. [Date last reviewed: 2019-03-14]
FBgn0003884	alphaTub84B	alpha-Tubulin at 84B	NA
FBgn0003885	alphaTub84D	alpha-Tubulin at 84D	α-Tubulin at 84D (αTub84D) encodes a protein involved in major cellular mechanisms such as formation of spindle apparatus or microtubular threads for transport of proteins or organelles. [Date last reviewed: 2019-03-21]
FBgn0003886	alphaTub85E	alpha-Tubulin at 85E	α-Tubulin at 85E (αTub85E) encodes the major α-Tubulin constituent of accessory and attachment cells of chordotonal organs. [Date last reviewed: 2019-03-21]
FBgn0003888	betaTub60D	beta-Tubulin at 60D	NA
FBgn0003890	betaTub97EF	beta-Tubulin at 97EF	β-Tubulin at 97EF (βTub97EF) is one of five distinct paralogs that codes for a β-tubulin protein. β-tubulin protein can polymerize into microtubules after heterodimerization with an α-tubulin protein. βTub97EF expression is tissue-specific and up-regulated at low temperature. Microtubules containing this beta-tubulin are relatively stable. [Date last reviewed: 2018-09-20]
FBgn0003891	tud	tudor	NA
FBgn0003892	ptc	patched	patched (ptc) is a segment polarity gene that encodes a 12-pass transmembrane protein involved in Hh signalling regulation. ptc product contributes to the binding, internalization and degradation of the ligand encoded by hh, limiting its activity spatial range. ptc product also represses the constitutive signaling activity of the transmembrane protein encoded by smo. [Date last reviewed: 2018-09-20]
FBgn0003941	RpL40	Ribosomal protein L40	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0003942	RpS27A	Ribosomal protein S27A	NA
FBgn0003943	Ubi-p63E	Ubiquitin-63E	Ubiquitin-63E (Ubi-p63E) encodes a polyubiquitin precursor: once processed by deubiquitinating enzymes, it produces ten ubiquitin molecules, which are predominantly conjugated to target proteins. Ubiquitin conjugation is involved in a wide range of biological processes, such as protein degradation, endocytosis of plasma membrane proteins, protein trafficking, DNA-damage response and inflammation and immune system response. [Date last reviewed: 2018-09-06]
FBgn0003950	unc	uncoordinated	uncoordinated (unc) encodes a basal body-associated protein that is required for normal ciliogenesis. unc depletion results in spermatids with defective flagella and truncated cilia in mechanosensory and chemosensory neurons. Its name arises from the severe uncoordination phenotype due to a lack of proprioceptive sensory feedback. [Date last reviewed: 2019-03-21]
FBgn0003963	ush	u-shaped	u-shaped (ush) encodes a member of the Friend of GATA (FOG) multi-type zinc finger protein family, which bind GATA factors (like those encoded by srp or pnr). These complexes can interface with major signal transduction pathways such as TGFbeta, Hedgehog, JAK/STAT and Insulin/PI3K to regulate diverse biological processes such as embryonic development, heart, blood and neural development and body size. [Date last reviewed: 2018-09-06]
FBgn0003964	usp	ultraspiracle	NA
FBgn0003969	vap	vacuolar peduncle	vacuolar peduncle (vap) encodes a GTPase-activating protein for Ras-family small GTPases that functions in the intracellular Ras-MAP kinase pathway. vap loss produces age-dependent neurodegeneration in the adult brain. The product of vap function in neuronal survival is mediated through the EGF receptor pathway and Rab5-dependent endocytosis. [Date last reviewed: 2019-03-21]
FBgn0003977	vir	virilizer	NA
FBgn0003978	vls	valois	valois (vls) encodes a protein that functions as the substrate recognition platform for the protein arginine methyltransferase encoded by csul. Primary substrates of the products of csul and vls are the spliceosomal Sm proteins. The product of vls is also required for proper localization of the product of tud to the posterior pole of the oocyte during germ line specification. [Date last reviewed: 2019-03-21]
FBgn0003984	vn	vein	vein (vn) encodes a secreted neuregulin-like EGFR ligand. It has weaker intrinsic activity, and a lower receptor affinity, than the TGFalpha-like ligand encoded by spi. It has roles in growth and patterning of tissues including muscle, midgut, ovary, trachea, glia, eye, leg, and wing. [Date last reviewed: 2019-03-21]
FBgn0003996	w	white	white (w) encodes a member of the ABCG2 class of transporters, transporting molecules such as cyclic GMP, biogenic amines and pigments including drosopterins and ommochromes. Mutation of w results in viable flies with white eyes. A shortened version of the gene (mini-w) has been widely used in transformation constructs as a selectable marker. [Date last reviewed: 2019-03-21]
FBgn0003997	hid	head involution defective	NA
FBgn0004034	y	yellow	yellow (y) is the founding gene of the Yellow family. Lack of y function results in an abnormal male courtship behavior and a characteristic yellow color of the adult cuticle and larval mouthparts. [Date last reviewed: 2019-03-21]
FBgn0004047	Yp3	Yolk protein 3	NA
FBgn0004049	yrt	yurt	yurt (yrt) encodes a membrane-associated protein. It contributes to apical-basal polarity and permeability of septate junctions. In differentiating epithelial cells, it counteracts apical polarity proteins to sustain lateral membrane stability and apical-basal polarity. In fully differentiated cells, the product of yrt acts as a negative regulatory component of the crb complex and limits apical membrane growth. [Date last reviewed: 2019-03-21]
FBgn0004050	z	zeste	zeste (z) encodes a sequence-specific DNA-binding protein. It is often found in the proximal promoter region of many genes where it helps to recruit the BRM nucleosome remodeling complex. It is best known for the pairing-dependent repressive effects produced by some of its mutants on target genes, especially the w gene. [Date last reviewed: 2019-03-21]
FBgn0004055	uzip	unzipped	unzipped (uzip) encodes a cell adhesion molecule that genetically interacts with CadN. Its biological function includes regulation of axon guidance. [Date last reviewed: 2019-03-21]
FBgn0004057	Zw	Zwischenferment	Zwischenferment (Zw) encodes a cytosolic enzyme that catalyzes the oxidation of Glucose-6-phosphate to 6-phosphogluconate with the concomitant reduction of NADP[+] to NADPH. The products of Zw and Pgd are the two NADP[+] reducing enzymes in the pentose phosphate pathway. [Date last reviewed: 2019-03-21]
FBgn0004066	Prosalpha4	Proteasome alpha4 subunit	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0004087	Dhfr	Dihydrofolate reductase	Dihydrofolate reductase (Dhfr) encodes an NADPH-dependent enzyme used to convert folic acid and dihydrofolate to tetrahydrofolate, which is used as a cofactor for the biosynthesis of purines, thymidylate, and several amino acids. Dhfr product contributes to cell proliferation and cell growth. [Date last reviewed: 2018-09-06]
FBgn0004101	bs	blistered	NA
FBgn0004103	Pp1-87B	Protein phosphatase 1 at 87B	NA
FBgn0004106	Cdk1	Cyclin-dependent kinase 1	Cyclin-dependent kinase 1 (Cdk1) encodes a catalytic protein kinase subunit that can only become active after association with either CycA, CycB or CycB3 products. The protein kinase activities of these complexes (CycA-Cdk1, CycB-Cdk1, CycB3-Cdk1) control important aspects of progression through the cell cycle. Functionally, the different Cdk1 complexes are partially redundant. They phosphorylate hundreds of target proteins and are most important for progression into and through mitotic and meiotic M phases. [Date last reviewed: 2019-09-26]
FBgn0004107	Cdk2	Cyclin-dependent kinase 2	Cyclin-dependent kinase 2 (Cdk2) encodes a catalytic protein kinase subunit that can only become active after association with the product of CycE. The protein kinase activity of the CycE-Cdk2 complex controls important aspects of progression through the G1 and S phases of the cell cycle. In addition, periodic CycE-Cdk2 activity regulates progression through endoreduplication cycles. [Date last reviewed: 2019-03-07]
FBgn0004108	Nrt	Neurotactin	NA
FBgn0004132	boca	boca	boca (boca) encodes an endoplasmic reticulum protein that is evolutionarily conserved. It is required for the intracellular trafficking of members of the low-density lipoprotein family of receptors, including the one encoded by arr. As such, boca mutants are compromised for a number of pathways including Wingless signaling. [Date last reviewed: 2019-03-21]
FBgn0004133	blow	blown fuse	blown fuse (blow) encodes a cytoplasmic protein required for myoblast fusion. It regulates actin cytoskeletal dynamics via modulating the stability of the WASp-Vrp1 complex. [Date last reviewed: 2019-03-07]
FBgn0004167	kst	karst	karst (kst) encodes a protein that, together with the product of α-Spec, crosslinks F-actin and acts as a molecular scaffold. It is recruited to the apical membrane of epithelial cells by the apical determinant encoded by crb. The roles of the product of kst include endosomal trafficking, cell adhesion, cell signaling and growth control. [Date last reviewed: 2019-03-14]
FBgn0004177	mts	microtubule star	microtubule star (mts) encodes the catalytic subunit of protein phosphatase 2A. It is involved in various developmental processes and signaling pathways, such as Hh signaling and Wingless signaling. [Date last reviewed: 2018-09-06]
FBgn0004179	Csp	Cysteine string protein	Cysteine string protein (Csp) encodes a synaptic vesicle-associated co-chaperone of Hsc70 that is vital for presynaptic proteostasis and maintenance of synaptic function. The substartes of the product of Csp include SNARE proteins and the product of shi, which mediate synaptic vesicle exo- and endocytosis respectively. [Date last reviewed: 2019-03-07]
FBgn0004197	Ser	Serrate	NA
FBgn0004198	ct	cut	cut (ct) encodes a homeoprotein that functions as a transcriptional factor in many different cells such as wing disc, muscle, oocyte and sense organ cells. It is a regulator of type-specific neuronal identity in the peripheral nervous system. ct is expressed at variable levels in the dendritic arborization (DA) neurons and these levels control the different dendritic morphologies specific for each class of DA neurons. [Date last reviewed: 2019-03-07]
FBgn0004227	nonA	no on or off transient A	NA
FBgn0004237	Hrb87F	Heterogeneous nuclear ribonucleoprotein at 87F	Heterogeneous nuclear ribonucleoprotein at 87F (Hrb87F) encodes a hnRNP-A family RNA-binding protein, involved in gene expression and RNA processing. It is an essential component of the nucleoplasmic omega speckles and necessary for telomere maintenance. Hrb87F null mutants show defects in development, female fertility and stress tolerance. [Date last reviewed: 2018-09-06]
FBgn0004359	T48	Transcript 48	Transcript 48 (T48) encodes a protein with a predicted signal peptide and a potential transmembrane domain. During gastrulation, the product of T48 contributes to apical constriction by recruitment of the Rho GEF encoded by RhoGEF2 to the apical cell membrane and functions downstream of the transcription factor encoded by twi. [Date last reviewed: 2019-03-21]
FBgn0004362	HmgD	High mobility group protein D	High mobility group protein D (HmgD) encodes a highly abundant chromosomal protein involved in DNA bending and chromatin organization. [Date last reviewed: 2018-09-06]
FBgn0004363	porin	porin	porin (porin) encodes a beta-barrel channel protein localized in the outer membrane of mitochondria that conducts translocation of various ions and metabolites between cytoplasm and mitochondria. It plays roles in mitochondria dynamics and mitophagy, and is ubiquitinated by the E3 ligases encoded by park and Mul1. [Date last reviewed: 2019-03-14]
FBgn0004367	mei-41	meiotic 41	meiotic 41 (mei-41) encodes a protein that, together with mus304, promotes DNA damage-dependent responses, including repair and cell cycle checkpoint signalling. [Date last reviewed: 2019-03-14]
FBgn0004368	Ptp4E	Protein tyrosine phosphatase 4E	Protein tyrosine phosphatase 4E (Ptp4E) encodes a transmembrane receptor tyrosine phosphatase closely related to the product of Ptp10D. Ptp4E single mutants have no known phenotypes. However, Ptp4E-Ptp10D double mutants have lethal respiratory defects. The product of Ptp4E regulates signaling through the receptor tyrosine kinases encoded by Egfr, btl and Pvr. [Date last reviewed: 2019-03-14]
FBgn0004369	Ptp99A	Protein tyrosine phosphatase 99A	Protein tyrosine phosphatase 99A (Ptp99A) encodes a transmembrane receptor tyrosine phosphatase. Its single mutants have no known phenotypes, but Ptp99A synergizes with Ptp69D to increase the penetrance of the Ptp69D motor axon defects. Ptp99A mutations also suppress the 'bypass' motor axon phenotype produced by Lar mutations. [Date last reviewed: 2019-03-14]
FBgn0004370	Ptp10D	Protein tyrosine phosphatase 10D	Protein tyrosine phosphatase 10D (Ptp10D) encodes a transmembrane receptor tyrosine phosphatase closely related to the product of Ptp4E. Ptp4E-Ptp10D double mutants have lethal respiratory defects. Ptp10D-Ptp69D double mutants have a strong phenotype in which embryonic CNS axons abnormally cross the ventral midline. The product of Ptp10D regulates signaling through the receptor tyrosine kinases encoded by Egfr, btl and Pvr. It also binds to the product of sas to regulate its signaling in glia. [Date last reviewed: 2019-03-14]
FBgn0004373	fwd	four wheel drive	four wheel drive (fwd) encodes a Golgi-localized lipid kinase that synthesizes phosphatidylinositol 4-phosphate from phosphatidylinositol. It is involved in spermatocyte cytokinesis and male fertility. [Date last reviewed: 2019-03-07]
FBgn0004374	neb	nebbish	nebbish (neb) encodes a microtubule motor protein that interacts with PP1 phosphatases and is involved in chromosome segregation. [Date last reviewed: 2019-07-11]
FBgn0004378	Klp61F	Kinesin-like protein at 61F	Kinesin-like protein at 61F (Klp61F) encodes a member of the kinesin-5 family of cytoskeletal motor proteins. It allows the crosslinking and sliding apart of adjacent microtubules. This 'sliding filament mechanism' is critical for many aspect of mitosis and chromosome segregation. [Date last reviewed: 2019-03-14]
FBgn0004379	Klp67A	Kinesin-like protein at 67A	Kinesin-like protein at 67A (Klp67A) encodes a microtubule motor protein involved in chromosome congression and mitotic spindle morphogenesis. [Date last reviewed: 2019-07-11]
FBgn0004380	Klp64D	Kinesin-like protein at 64D	Kinesin-like protein at 64D (Klp64D) encodes the kinesin-2α motor subunit of the heterotrimeric kinesin-2. It associates with the products of Klp68D and Kap3. It plays an essential role in sensory cilia assembly and axonal transport. [Date last reviewed: 2019-03-14]
FBgn0004381	Klp68D	Kinesin-like protein at 68D	Kinesin-like protein at 68D (Klp68D) encodes the kinesin-2β motor subunit of the heterotrimeric kinesin-2. It associates with the products of Klp64D and Kap3. It plays an essential role in the sensory cilia assembly, microtubule organization in dendrites, and axonal transport. [Date last reviewed: 2019-03-14]
FBgn0004387	Klp98A	Kinesin-like protein at 98A	NA
FBgn0004390	RasGAP1	Ras GTPase activating protein 1	NA
FBgn0004391	shtd	shattered	shattered (shtd) encodes the largest subunit that forms the scaffold of the Anaphase Promoting Complex/Cyclosome (APC/C) E3 ubiquitin ligase. APC/C is active during mitosis and G1 phases of the cell cycle to mediates the degradation of cyclins and other key cell cycle regulators, which triggers the metaphase to anaphase transition and the exit from mitosis. [Date last reviewed: 2018-09-06]
FBgn0004395	unk	unkempt	unkempt (unk) encodes a highly conserved protein with roles in mRNA binding and ubiquitination. Together with the product of hdc, it acts downstream of the product of Mtor to regulate photoreceptor differentiation during eye development. [Date last reviewed: 2019-03-21]
FBgn0004396	CrebA	Cyclic-AMP response element binding protein A	Cyclic-AMP response element binding protein A (CrebA) encodes a leucine-zipper transcription factor that upregulates genes encoding protein components of the canonical secretory pathway and tissue-specific genes in the salivary gland and epidermis. [Date last reviewed: 2019-03-07]
FBgn0004397	Vinc	Vinculin	Vinculin (Vinc) encodes a key mechanoeffector of cell-cell and cell-extracellular matrix adhesion. It binds to the products of rhea and α-Cat, when they are stretched by force, and links them to actin. Vinc mutant flies are viable and fertile although mild defects have been documented in muscle attachment and heart function. [Date last reviewed: 2018-09-06]
FBgn0004400	rhi	rhino	rhino (rhi) encodes an ovary-restricted heterochromatin protein 1 gene required for female fertility. It silences germline transposable elements by promoting transcription of the small RNAs encoded in Piwi-RNAclusters. [Date last reviewed: 2018-09-06]
FBgn0004401	Pep	Protein on ecdysone puffs	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0004403	RpS14a	Ribosomal protein S14a	NA
FBgn0004404	RpS14b	Ribosomal protein S14b	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0004406	PolG1	DNA polymerase gamma subunit 1	DNA polymerase gamma subunit 1 (PolG1) encodes the catalytic subunit of mitocondrial DNA polymerase gamma, which is responsible for the replication and repair of the mitochondrial genome. [Date last reviewed: 2019-12-19]
FBgn0004419	me31B	maternal expression at 31B	NA
FBgn0004432	Cyp1	Cyclophilin 1	NA
FBgn0004435	Galphaq	G protein alpha q subunit	G protein α q subunit (Gαq) encodes an alpha subunit of a heterotrimeric G-protein that functions downstream of GPCR signaling. It contributes to neuronal development, olfaction, flight, learning and memory. [Date last reviewed: 2019-03-07]
FBgn0004436	Ubc6	Ubiquitin conjugating enzyme 6	Ubiquitin conjugating enzyme 6 (Ubc6) encodes an enzyme that acts together with E3 ubiquitin ligases to transfer ubiquitin to target proteins. [Date last reviewed: 2019-03-14]
FBgn0004449	Ten-m	Tenascin major	Tenascin major (Ten-m) encodes a type II dimeric transmembrane protein whose extracellular domain mediates interactions with itself and with its paralogous protein encoded by Ten-a. It also interacts intracellularly with cytoskeleton regulatory proteins. Ten-m product regulates synaptic partner matching and axon guidance in the embryonic nervous system, as well as synaptic organization in olfactory and neuromuscular systems. [Date last reviewed: 2018-09-06]
FBgn0004456	mew	multiple edematous wings	multiple edematous wings (mew) encodes one of 5 fly integrin alpha subunits, and when in a heterodimer with an integrin beta subunit makes a receptor for the extracellular matrix protein laminin. It is required in numerous tissues for cell migration, adhesion between cell layers, and cell differentiation. [Date last reviewed: 2019-03-14]
FBgn0004463	Polr3B	RNA polymerase III subunit B	RNA polymerase III subunit B (Polr3B) encodes one of the subunits that forms the multi-protein RNA Polymerase III holoenzyme. RNA Polymerase III transcribes several types of small non-coding RNAs in the nuclear genome including tRNAs and 5SrRNA. [Date last reviewed: 2018-09-06]
FBgn0004465	Su(P)	Suppressor of ref(2)P sterility	NA
FBgn0004507	GlyP	Glycogen phosphorylase	NA
FBgn0004509	Fur1	Furin 1	NA
FBgn0004510	Ets97D	Ets at 97D	NA
FBgn0004512	Mdr49	Multi drug resistance 49	Multi drug resistance 49 (Mdr49) encodes drug transmembrane transporter that belongs to the ABCB transporter subfamily and contributes to insecticide resistance. [Date last reviewed: 2018-09-06]
FBgn0004556	Dbp73D	Dead box protein 73D	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0004569	aos	argos	NA
FBgn0004574	Rop	Ras opposite	NA
FBgn0004583	ex	expanded	expanded (ex) encodes a FERM-domain containing protein that localizes to apical cell-cell junctions, where it promotes Hippo signaling by physically interacting with multiple Hippo pathway components. Through its regulation of Hippo signaling, the product of ex functions as an inhibitor of growth. [Date last reviewed: 2019-03-07]
FBgn0004584	Rrp1	Recombination repair protein 1	NA
FBgn0004587	B52	B52	NA
FBgn0004595	pros	prospero	prospero (pros) encodes a protein that promotes the expression of neural differentiation genes and represses neuroblast stem cell identity genes and cell cycle proliferation genes; it is also important for astrocyte development. The product of pros is asymmetrically localized to the basal cortex during neuroblast asymmetric cell division, resulting in its partioning into GMC daughter cells, where it translocates into the nucleus. [Date last reviewed: 2019-03-14]
FBgn0004597	CycC	Cyclin C	NA
FBgn0004598	Fur2	Furin 2	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0004606	zfh1	Zn finger homeodomain 1	NA
FBgn0004611	Plc21C	Phospholipase C at 21C	Phospholipase C at 21C (Plc21C) encodes a phospholipase C beta involved in olfaction and flight. It functions downstream of G-protein-coupled receptors coupled to Gq. [Date last reviewed: 2018-09-06]
FBgn0004629	Cys	Cystatin-like	NA
FBgn0004635	rho	rhomboid	rhomboid (rho) encodes an intra-membrane serine protease that processes the membrane precursors of Egfr ligands. Its roles include growth regulation, cell survival and developmental patterning. [Date last reviewed: 2019-03-14]
FBgn0004636	Rap1	Rap1 GTPase	Rap1 GTPase (Rap1) encodes a small GTPase in the Ras superfamily. When GTP bound, it binds to a number of different effectors, one of which is the product of scno. Together they regulate many morphogenetic movements including mesoderm invagination and dorsal closure, help establish apical-basal polarity during cellularization, regulate macrophage migration, help define neuroblast asymmetric division, and play a role in planar cell polarity in the imaginal discs. [Date last reviewed: 2019-03-14]
FBgn0004638	drk	downstream of receptor kinase	downstream of receptor kinase (drk) encodes an adaptor protein that recognizes phosphorylated tyrosine residues of membrane receptors and triggers the Ras/Raf/MAPK pathway. drk product contributes to the regulation of cytoskeletal organization and participates in developmental and cognitive processes (associative learning, anesthesia resistant memory). [Date last reviewed: 2018-09-06]
FBgn0004643	Zw10	Zeste-white 10	Zeste-white 10 (Zw10) encodes a subunit of the RZZ complex located at the kinetochores of chromosomes. The RZZ complex plays an essential role in the spindle assembly checkpoint that ensures proper connections between chromosomes and the mitotic spindle. The product of Zw10 is also found on the Golgi stacks and endoplasmic reticulum, where it functions in membrane formation and trafficking. [Date last reviewed: 2019-10-03]
FBgn0004646	ogre	optic ganglion reduced	optic ganglion reduced (ogre) encodes one of the innexin subunits spanning the membrane 4 times. Together with the products of Inx2 and Inx3, it forms homo or hetero oligomers forming gap junctions, which allow the transfer of small solute between cells. [Date last reviewed: 2019-03-14]
FBgn0004647	N	Notch	NA
FBgn0004648	svr	silver	NA
FBgn0004650	fs(1)N	female sterile (1) Nasrat	female sterile (1) Nasrat (fs(1)N) encodes encodes a protein that is required, along with the products of fs(1)M3 and clos, for their accumulation at the vitelline membrane and function in vitelline membrane integrity and Torso receptor activation. [Date last reviewed: 2019-09-26]
FBgn0004652	fru	fruitless	fruitless (fru) encodes a BTB zinc finger transcription factor that contributes to sexual differentiation of the neural circuits underlying male sexual behavior. [Date last reviewed: 2019-03-07]
FBgn0004654	Pgd	Phosphogluconate dehydrogenase	Phosphogluconate dehydrogenase (Pgd) encodes a cytosolic enzyme that catalyzes the oxidation of 6-phosphogluconate to ribulose 5-phosphate, with the concomitant reduction of NADP[+] to NADPH. The products of Pgd and Zw are the two NADP[+] reducing enzymes in the pentose phosphate pathway. [Date last reviewed: 2019-03-14]
FBgn0004655	wapl	wings apart-like	wings apart-like (wapl) encodes a protein that interacts with the product of pds5 to form the releasin complex that enables sister chromatid separation at mitosis by removing the cohesin ring complex from chromosomes. It also influences gene activation and silencing through interactions with cohesin. [Date last reviewed: 2019-03-21]
FBgn0004656	fs(1)h	female sterile (1) homeotic	female sterile (1) homeotic (fs(1)h) encodes a Bromodomain and Extra-Terminal domain (BET) family of protein, characterized by the presence of two tandem bromodomains and an extra-terminal (ET) domain. BET proteins can bind acetylated lysine residues in histones and regulate transcription. The proteins encoded by fs(1)h and human BRD2 possess protein kinase activity. [Date last reviewed: 2021-01-21]
FBgn0004657	mys	myospheroid	myospheroid (mys) encodes a β subunit of the integrin dimer. Integrin transmembrane receptors function as a link for the extracellular matrix and the intracellular actin cytoskeleton. The product of mys acts as adhesion/signaling protein regulating cellular adhesion, migration and survival. [Date last reviewed: 2019-03-14]
FBgn0004687	Mlc-c	Myosin light chain cytoplasmic	Myosin light chain cytoplasmic (Mlc-c) encodes a subunit of the myosin complex that is involved in actin filament-based movement. [Date last reviewed: 2019-07-11]
FBgn0004698	Xpc	Xeroderma pigmentosum, complementation group C	Xeroderma pigmentosum, complementation group C (Xpc) encodes a protein involved in recognition of DNA damage and recruitment of nucleotide excision repair proteins. [Date last reviewed: 2019-03-21]
FBgn0004797	mdy	midway	midway (mdy) encodes an acyl coenzyme A: diacylglycerol acyltransferase that functions in the formation of triglycerides. Lack of mdy leads to female sterility and impaired fat metabolism in larvae and adults. [Date last reviewed: 2019-03-14]
FBgn0004811	fs(2)ltoPP43	female sterile (2) ltoPP43	NA
FBgn0004828	His3.3B	Histone H3.3B	Histone H3.3B (His3.3B) encodes one of two single copy histone H3 variants. His3.3A and His3.3B transcription is not under control of the cell cycle. His3.3B has a long 3'-UTR (> 1500 nucleotides) and can be processed at different polyadenylation sites which are tissue-specific. [Date last reviewed: 2019-03-21]
FBgn0004832	Xpac	Xeroderma pigmentosum group A-like	NA
FBgn0004837	Su(H)	Suppressor of Hairless	NA
FBgn0004838	Hrb27C	Heterogeneous nuclear ribonucleoprotein at 27C	NA
FBgn0004852	Ac76E	Adenylyl cyclase 76E	NA
FBgn0004855	Polr2I	RNA polymerase II subunit I	NA
FBgn0004856	Bx42	Bx42	Bx42 (Bx42) encodes a nuclear protein that acts as a cofactor in Notch signalling pathway. [Date last reviewed: 2019-03-07]
FBgn0004858	elB	elbow B	NA
FBgn0004859	ci	cubitus interruptus	cubitus interruptus (ci) encodes a Zn-finger family of transcription factor. It contributes to Hedgehog (Hh) signaling pathway that is involved in pattern formation and growth control. The product of ci undergoes limited proteolysis to be converted into a truncated form that function as a transcription repressor in the absence of the ligand encoded by hh but is converted into a full-length transcription activator in the presence of the product of hh. [Date last reviewed: 2019-03-07]
FBgn0004860	ph-d	polyhomeotic distal	polyhomeotic distal (ph-d) encodes a stoichiometric subunit of the Polycomb repressive complex 1. The complex silences a variety of genes involved in developmental patterning, regulation of cell proliferation, differentiation and polarity. Together with its paralog ph-p, ph-d functions as a tumor suppressor gene. [Date last reviewed: 2019-03-14]
FBgn0004861	ph-p	polyhomeotic proximal	polyhomeotic proximal (ph-p) encodes a stoichiometric subunit of the Polycomb repressive complex 1. The complex silences a variety of genes involved in developmental patterning, regulation of cell proliferation, differentiation and polarity. Together with its paralog ph-d, ph-p functions as a tumor suppressor gene. [Date last reviewed: 2019-03-14]
FBgn0004864	hop	hopscotch	hopscotch (hop) encodes a non-receptor tyrosine kinase for interleukin-like ligands (encoded by upd1, upd2, and upd3) and functions in the JAK-STAT signaling pathway. It is involved in embryonic segmentation, cell proliferation, and cell migration. [Date last reviewed: 2019-03-07]
FBgn0004865	Eip78C	Ecdysone-induced protein 78C	NA
FBgn0004867	RpS2	Ribosomal protein S2	Ribosomal protein S2 (RpS2) encodes a highly conserved component of the 40S ribolomal comlex. RpS2 product controls the assembly and nuclear export of the pre-ribosome and appears to have a specific function during oogenesis. [Date last reviewed: 2018-09-06]
FBgn0004868	Gdi	GDP dissociation inhibitor	GDP dissociation inhibitor (Gdi) encodes a GDP-dissociation inhibitor. [Date last reviewed: 2019-09-19]
FBgn0004870	bab1	bric a brac 1	bric a brac 1 (bab1) encodes a transcriptional regulator that functions partially redundantly with the product of bab2. It is part of the conserved proximal-distal gene regulatory network module. It contributes to pattern formation, ovary morphogenesis, abdominal pigmentation and olfactory receptor neuron fate diversity. [Date last reviewed: 2019-03-07]
FBgn0004872	piwi	P-element induced wimpy testis	NA
FBgn0004875	enc	encore	encore (enc) encodes a protein involved in the regulation of germline mitoses. It promotes the upregulation of grk mRNA translation in the dorsal anterior corner of the oocyte, allowing normal dorso-ventral pattern formation. [Date last reviewed: 2019-03-07]
FBgn0004876	cdi	center divider	center divider (cdi) encodes a serine/threonine kinase that stimulates the formation of actin fibers and focal adhesions through phosphorylation of the F-actin depolimerization factor tsr. [Date last reviewed: 2018-09-13]
FBgn0004882	orb	oo18 RNA-binding protein	oo18 RNA-binding protein (orb) encodes a RNA-binding protein required for the formation of the egg chamber and establishment of polarity during oogenesis. It is involved in mRNA polyadenylation and the regulation of osk mRNA translation. [Date last reviewed: 2019-09-19]
FBgn0004888	Scsalpha1	Succinyl-coenzyme A synthetase alpha subunit 1	NA
FBgn0004889	tws	twins	twins (tws) encodes a regulatory subunit of protein phosphatase 2A (PP2A) and is involved in many developmental processes and signaling pathways. [Date last reviewed: 2018-09-13]
FBgn0004893	bowl	brother of odd with entrails limited	brother of odd with entrails limited (bowl) encodes a member of the Odd-skipped (Odd) family of zinc finger proteins involved in developmental patterning and cell fate specification. Its localization in the nucleus is regulated by the nuclear protein encoded by lin and the the product of drm with opposing roles. [Date last reviewed: 2019-03-07]
FBgn0004901	Prat	Phosphoribosylamidotransferase	Phosphoribosylamidotransferase (Prat) encodes a type-2 glutamine amidotransferase that converts phosphoribosylpyrophosphate to phosphoribosylamine using glutamine. It is an essential enzyme in the pathway for de novo synthesis of the purine nucleotide inosine monophosphate (IMP). IMP is the precursor for purine nucleotides required for nucleic acids, energy transfer, cell signaling, and coenzymes. [Date last reviewed: 2019-03-14]
FBgn0004903	Rb97D	Ribonuclear protein at 97D	NA
FBgn0004907	14-3-3zeta	14-3-3zeta	14-3-3ζ (14-3-3ζ) encodes three acidic protein isoforms due to alternative splicing. The isoforms homo- and heterodimerize with each other and other members of the family. It functions in multiple signaling pathways, most prominently in the Ras/MAPK cascade. It is involved in epithelial cell polarity, development of the eye, embryogenesis and in adult associative learning. [Date last reviewed: 2019-03-07]
FBgn0004908	Arl2	ADP ribosylation factor-like 2	ADP ribosylation factor-like 2 (Arl2) encodes a small GTPase within the ADP-ribosylation factor-like family. Arl2 product functions as a central regulator of microtubule growth and asymmetric division of neuroblasts. [Date last reviewed: 2018-09-13]
FBgn0004913	Gnf1	Germ line transcription factor 1	Germ line transcription factor 1 (Gnf1) encodes the largest subunit of the replication factor C (RFC). RFC is a clamp loader that loads a sliding clamp (PCNA) trimer to the DNA replication fork. [Date last reviewed: 2018-09-13]
FBgn0004914	Hnf4	Hepatocyte nuclear factor 4	Hepatocyte nuclear factor 4 (Hnf4) encodes a protein that regulates lipid mobilization and fatty acid beta-oxidation during larval stages. Its expression increases greatly at the onset of adulthood when it promotes glucose-stimulated ILP secretion from the insulin-producing cells, maintains glucose homeostasis, and supports mitochondrial function. [Date last reviewed: 2019-03-07]
FBgn0004915	TfIIB	Transcription factor IIB	Transcription factor IIB (TfIIB) encodes a basal transcription factor that binds to the TATA box-binding protein. It is required for the initiation of transcription by RNA polymerase II. [Date last reviewed: 2019-03-14]
FBgn0004919	gol	goliath	goliath (gol) encodes an E3 ubiquitin ligase, whose cellular substrates are unknown. During embyrogenesis gol is expressed in fusion-competence myoblasts of the somatic and visceral mesoderm. [Date last reviewed: 2019-03-07]
FBgn0004921	Ggamma1	G protein gamma 1	G protein γ 1 (Gγ1) encodes a protein involved in the G-protein coupled receptor signaling pathway. Gγ1-product regulates actomyosin dynamics and contributes to heart morphogenesis, asymmetric neuroblast division and convergent extension movements during gastrulation. [Date last reviewed: 2019-03-07]
FBgn0004924	Top1	Topoisomerase 1	Topoisomerase 1 (Top1) encodes a topoisomerase with essential functions in cell proliferation during stages of oogenesis, embryogenesis, larva, and pupa. [Date last reviewed: 2019-03-14]
FBgn0004926	eIF2beta	eukaryotic translation initiation factor 2 subunit beta	NA
FBgn0004957	por	porcupine	porcupine (por) encodes an O-acyltransferase that is an essential component of the Wingless/Wnt pathway by mediating lipidation of the product of wg. It targets the product of wg to secretory vesicles that deliver the ligand to specialized microdomains at the cell surface where it can be packaged for secretion. [Date last reviewed: 2019-03-14]
FBgn0005198	gig	gigas	gigas (gig) encodes a tumour suppressor protein that, together with with the product of Tsc1, controls cellular growth via antagonizing insulin and TOR signalling pathways. [Date last reviewed: 2019-03-07]
FBgn0005278	Sam-S	S-adenosylmethionine Synthetase	NA
FBgn0005322	nmd	no mitochondrial derivative	NA
FBgn0005355	Su(fu)	Suppressor of fused	Suppressor of fused (Su(fu)) encodes a negative regulator of the Hedgehog signaling pathway. It forms a complex with the transcription factor encoded by ci to inhibit its activity. [Date last reviewed: 2019-09-26]
FBgn0005386	ash1	absent, small, or homeotic discs 1	absent, small, or homeotic discs 1 (ash1) encodes a histone methyltransferase involved in transcription regulation. [Date last reviewed: 2018-09-13]
FBgn0005411	U2af50	U2 small nuclear riboprotein auxiliary factor 50	U2 small nuclear riboprotein auxiliary factor 50 (U2af50) encodes the large subunit of the heterodimeric complex U2AF. U2AF binds to the intron pyrimidine tract between the branchpoint and the 3' splice site and targets U2 snRNP to the branch site early in spliceosome assembly. [Date last reviewed: 2018-09-13]
FBgn0005427	ewg	erect wing	erect wing (ewg) encodes a transcription factor that is essential for synaptic growth at neuromuscular junctions, specification of photoreceptor subtypes, and formation of indirect flight muscles. ewg product has also been linked to the Hippo and Wingless pathways and serves as a major target of the RNA-binding protein encoded by elav. [Date last reviewed: 2018-09-13]
FBgn0005533	RpS17	Ribosomal protein S17	Ribosomal protein S17 (RpS17) encodes an essential component of the ribosomal 40S subunit. RpS17 mutants have dominant, haploinsufficient effects on cellular and organismal growth rate, and on bristle size. [Date last reviewed: 2019-03-14]
FBgn0005536	Mbs	Myosin binding subunit	Myosin binding subunit (Mbs) encodes a regulatory subunit of myosin phosphatase. It interacts with the catalytic subunit of the myosin phosphatase encoded by flw. It is involved in cell movement in various biological processes and in the arrest of constriction of contractile rings and ring canals during oogenesis. [Date last reviewed: 2019-03-14]
FBgn0005585	Calr	Calreticulin	Calreticulin (Calr) encodes a protein that contributes to olfactory behavior, central nervous system development and sleep. It also works as a marker for phagocytosis of apoptotic cells by phagocytes in embryonic stages. [Date last reviewed: 2018-09-13]
FBgn0005593	RpL7	Ribosomal protein L7	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0005596	yem	yemanuclein	yemanuclein (yem) is a maternally expressed gene essential in the oocyte for meiosis and in the zygote for male pronucleus chromatin assembly. yem encodes a chaperone of H3.3 histone variant in partnership with the protein encoded by Hira. It also interacts with components of the Cohesin and the synaptonemal complexes. [Date last reviewed: 2018-09-13]
FBgn0005612	Sox14	Sox box protein 14	Sox box protein 14 (Sox14) encodes a transcription factor involved in neurogenesis and metamorphosis. [Date last reviewed: 2019-09-12]
FBgn0005614	trpl	transient receptor potential-like	transient receptor potential-like (trpl) encodes a non-selective plasma membrane cation channel with modest Ca[2+] permeability. It is highly eye-enriched and contributes to the electrical response to light in photoreceptors. [Date last reviewed: 2019-03-14]
FBgn0005616	msl-2	male-specific lethal 2	male-specific lethal 2 (msl-2) encodes the key male-specific subunit of the male-specific-lethal dosage compensation complex. It induces or stabilizes all other components. Homozygous mutant males die, while msl-2 ectopic expression kills females. [Date last reviewed: 2019-03-14]
FBgn0005617	msl-1	male-specific lethal 1	male-specific lethal 1 (msl-1) encodes a protein that is thought to form a scaffold to organize the full male-specific-lethal dosage compensation complex, which increases male X chromosome transcription approximately two-fold. msl-1 homozygous mutant males die as larvae, while females are viable. [Date last reviewed: 2019-03-14]
FBgn0005624	Psc	Posterior sex combs	Posterior sex combs (Psc) was originally identified as a member of the Polycomb group of genes that regulate gene expression through epigenetic marks. [Date last reviewed: 2019-03-14]
FBgn0005631	robo1	roundabout 1	roundabout 1 (robo1) encodes a member of the Robo receptor family that uses the secreted glycoprotein encoded by sli as ligand and the products of Sdc and Dscam1 as co-receptors. It contributes to axon guidance and dendrite morphogenesis as well as regulating trachea and heart tube development. [Date last reviewed: 2019-03-14]
FBgn0005632	faf	fat facets	NA
FBgn0005636	nvy	nervy	nervy (nvy) is a member of the MTG family of genes that have both nuclear and cytosolic functions. nvy encodes a transcriptional repressor and an A kinase anchoring protein (AKAP). It regulates repulsive axon guidance and functions in Plexin and Notch signaling pathways. [Date last reviewed: 2018-09-20]
FBgn0005640	Eip63E	Ecdysone-induced protein 63E	Ecdysone-induced protein 63E (Eip63E) encodes a cyclin-dependent kinase that interacts with the product of CycY. It contributes to embryogenesis, larval development and metamorphosis. [Date last reviewed: 2019-08-01]
FBgn0005642	wdn	wings down	NA
FBgn0005648	Pabp2	Pabp2	Pabp2 (Pabp2) encodes a nuclear poly(A) binding protein that is involved in both the cleavage and polyadenylation steps of the nuclear cleavage/polyadenylation reaction. Cytoplasmic protein encoded by Pabp2 acts to shorten the poly(A) tails of specific mRNAs in oocytes and syncytial blastoderm embryos. [Date last reviewed: 2018-09-13]
FBgn0005649	Rox8	Rox8	Rox8 (Rox8) encodes a protein involved in the regulation of alternative mRNA splicing. [Date last reviewed: 2019-09-19]
FBgn0005655	PCNA	Proliferating cell nuclear antigen	NA
FBgn0005660	Ets21C	Ets at 21C	Ets at 21C (Ets21C) encodes a stress-inducible transcription factor that binds specifically to purine-rich DNA motifs. It cooperates with transcription factors acting downstream of the MAP kinase pathways to fine tune gene expression in response to stress, such as infection or oncogene activation. [Date last reviewed: 2019-03-21]
FBgn0005666	bt	bent	bent (bt) encodes the protein Projectin, a large protein associated with myosin thick filaments in insect muscles that contributes to the stiffness of flight muscle. [Date last reviewed: 2019-03-07]
FBgn0005670	Cyp4d1	Cytochrome P450 4d1	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0005671	Vha55	Vacuolar H[+]-ATPase 55kD subunit	NA
FBgn0005672	spi	spitz	spitz (spi) encodes the cardinal Egfr ligand that is produced as a transmembrane precursor and processed by the products of S and rho. Its roles include growth regulation, cell survival and developmental patterning. [Date last reviewed: 2019-03-14]
FBgn0005674	GluProRS	Glutamyl-prolyl-tRNA synthetase	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0005683	pie	pineapple eye	pineapple eye (pie) encodes a protein that contributes to viability of imaginal disc cells and affects germline stem cell renewal. It interacts genetically with the Jak/Stat and BMP pathways. [Date last reviewed: 2019-03-14]
FBgn0005694	Aef1	Adult enhancer factor 1	NA
FBgn0005695	gcl	germ cell-less	germ cell-less (gcl) encodes a conserved BTB (broad-complex, tramtrack, and bric-a-brac) protein that mediates transcriptional repression in the germline and the degradation of the receptor tyrosine kinase encoded by tor, which in turn allows germ cell formation. [Date last reviewed: 2019-03-07]
FBgn0005696	PolA2	DNA polymerase alpha subunit 2	NA
FBgn0005777	PpD3	Protein phosphatase D3	Protein phosphatase D3 (PpD3) encodes a protein required for mitosis. [Date last reviewed: 2019-08-01]
FBgn0008635	betaCOP	Coat Protein (coatomer) beta	Coat Protein (coatomer) β (βCOP) encodes a subunit of the COPI coatomer complex required for retrograde transport of vesicles from the golgi to the endoplasmic reticulum. [Date last reviewed: 2019-09-26]
FBgn0010015	CanA1	Calcineurin A1	NA
FBgn0010038	GstD2	Glutathione S transferase D2	NA
FBgn0010039	GstD3	Glutathione S transferase D3	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0010041	GstD5	Glutathione S transferase D5	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0010043	GstD7	Glutathione S transferase D7	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0010051	Itpr	Inositol 1,4,5,-trisphosphate receptor	Inositol 1,4,5,-trisphosphate receptor (Itpr) encodes an intracellular ligand gated calcium channel. It functions downstream of G-protein coupled receptors that activate Gq/PLCbeta signaling and generate inositol tris-phosphate. Itpr depletion affects ecdysone release, response to nutritional stress, lipid metabolism and flight. [Date last reviewed: 2019-09-26]
FBgn0010053	Jheh1	Juvenile hormone epoxide hydrolase 1	Juvenile hormone epoxide hydrolase 1 (Jheh1) expression changes are associated with increased tolerance to oxidative stress. [Date last reviewed: 2019-03-07]
FBgn0010078	RpL23	Ribosomal protein L23	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0010097	gammaTub37C	gamma-Tubulin at 37C	γ-Tubulin at 37C (γTub37C) encodes a maternally expressed member of the tubulin family. It localizes predominantly to centrosomes and plays an essential role in microtubule nucleation at the centrosomes. [Date last reviewed: 2019-03-21]
FBgn0010100	mAcon1	Mitochondrial aconitase 1	Mitochondrial aconitase 1 (mAcon1) encodes an enzyme that harbors an iron-sulfur cluster and catalyses the first step of the Krebs Cycle in mitochondria, converting citrate into isocitrate. [Date last reviewed: 2018-09-13]
FBgn0010113	hdc	headcase	headcase (hdc) encodes two proteins by translational readthrough of a single mRNA. It is an esg target in the trachea and presumably also in imaginal tissues. The readthrough product is necessary for hdc function in the trachea. [Date last reviewed: 2019-03-07]
FBgn0010173	RpA-70	Replication Protein A 70	NA
FBgn0010194	Wnt5	Wnt oncogene analog 5	Wnt oncogene analog 5 (Wnt5) encodes a member of the Wnt gene family and acts as a signalling ligand for the Ryk family of receptor tyrosine kinase-related Wnt receptors. Among other processes, the product of Wnt5 contributes to repulsive embryonic axon pathfinding, mushroom body growth and antennal lobe patterning. [Date last reviewed: 2018-09-13]
FBgn0010198	RpS15Aa	Ribosomal protein S15Aa	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0010213	Sod2	Superoxide dismutase 2 (Mn)	Superoxide dismutase 2 (Mn) (Sod2) encodes an enzyme that detoxifies superoxide radicals in mitochondria. The loss of Sod2 generates endogenous oxidative stress that results in reduced activity of critical mitochondrial enzymes, hypersensitivity to oxidative stress and neonatal lethality. A muscle restricted p38Kinase-Mef2-Sod2 signaling module influences life span and stress. [Date last reviewed: 2019-09-26]
FBgn0010215	alpha-Cat	alpha Catenin	NA
FBgn0010217	ATPsynbeta	ATP synthase, beta subunit	NA
FBgn0010220	Dbp45A	DEAD box protein 45A	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0010222	Nmdmc	NAD-dependent methylenetetrahydrofolate dehydrogenase	NA
FBgn0010223	Galphaf	G protein alpha f subunit	G protein α f subunit (Gαf) encodes a transcriptional target of the JAK/STAT pathway in blood cells where it regulates cell shape and function. [Date last reviewed: 2019-03-07]
FBgn0010225	Gel	Gelsolin	NA
FBgn0010226	GstS1	Glutathione S transferase S1	NA
FBgn0010228	HmgZ	HMG protein Z	NA
FBgn0010235	Klc	Kinesin light chain	"Kinesin light chain (Klc) encodes a component of the kinesin motor protein complex, which moves along microtubules to transport cytoplasmic ""cargoes"" such as mRNAs, protein complexes, and organelles. [Date last reviewed: 2019-03-14]"
FBgn0010238	Lac	Lachesin	Lachesin (Lac) encodes a cell surface protein that belongs to the Ig superfamily. It is required for the proper ultrastructural organisation of septate junctions. Lac is required for tracheal system morphogenesis and for muscle contractions associated with peristalsis. [Date last reviewed: 2018-09-13]
FBgn0010246	Myo61F	Myosin 61F	NA
FBgn0010247	Parp	Poly-(ADP-ribose) polymerase	Poly-(ADP-ribose) polymerase (Parp) encodes a nuclear enzyme associated with chromatin. It modifies acceptor proteins through assembly of poly(ADP-ribose) polymers. The poly(ADP-ribosyl)ating pathway regulates many nuclear functions, including DNA-repair, chromatin structure, and transcription initiation, as well as pre-mRNA fate via alternative splicing and translation. [Date last reviewed: 2019-09-26]
FBgn0010265	RpS13	Ribosomal protein S13	Ribosomal protein S13 (RpS13) encodes a structural constituent of ribosomes. [Date last reviewed: 2019-07-11]
FBgn0010269	Dsor1	Downstream of raf1	Downstream of raf1 (Dsor1) encodes a serine/threonine kinase that phosphorylates MAP kinase. It is activated by the product of Raf and acts downstream of receptor tyrosine kinases such as those encoded by tor, Egfr, and sev. [Date last reviewed: 2019-03-07]
FBgn0010278	Ssrp	Structure specific recognition protein	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0010280	Taf4	TBP-associated factor 4	TBP-associated factor 4 (Taf4) encodes a protein that forms part of the multisubunit basal transcription factor TFIIID. It is important in maintaining TFIIID stability for activator dependent transcription. It forms a histone-like pair with the product of Taf12. [Date last reviewed: 2019-03-14]
FBgn0010282	TfIIFalpha	Transcription factor IIFalpha	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0010287	Trf	TBP-related factor	TBP-related factor (Trf) is ubiquitiously expressed but upregulated in the central nervous system and the gonads of developing Drosophila. The majority of the product of Trf substitutes for the product of Tbp in Pol III transcription in complex with the product of Brf. The rest of the product of Trf initiates transcription of a small subset of PolII-transcribed genes regulating fly fertility and nervous system function. [Date last reviewed: 2019-03-14]
FBgn0010288	Uch	Ubiquitin carboxy-terminal hydrolase	NA
FBgn0010292	bys	by S6	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0010300	brat	brain tumor	brain tumor (brat) encodes a tumor suppressor that regulates proliferation in the brain. During neural stem cell division, it segregates into one daughter cell where it inhibits protein translation, preventing self-renewal and inducing differentiation. It also acts during oogenesis where it interacts with the products of nos and pum to suppress hb translation. [Date last reviewed: 2019-03-07]
FBgn0010303	hep	hemipterous	hemipterous (hep) encodes a serine/threonine protein kinase involved in the Jun-N-terminal kinase pathway by phosphorylating the product of bsk. [Date last reviewed: 2019-03-07]
FBgn0010309	pigeon	pigeon	pigeon (pigeon) encodes a member of the Gamma-secretase-activating protein family. [Date last reviewed: 2018-09-13]
FBgn0010313	corto	corto	corto (corto) encodes an Enhancer of Trithorax and Polycomb (ETP) protein that physically interacts with several Polycomb proteins (encoded by Pc, ph-d, ph-p, esc, E(z)) and ETP (encoded by Trl, Dsp1). It also interacts with the product of CycG, with the methylated product of RpL12 (RPL12K3me3), and co-regulates the transcription of genes involved in ribosome biogenesis. [Date last reviewed: 2019-03-21]
FBgn0010314	Cks30A	Cyclin-dependent kinase subunit 30A	Cyclin-dependent kinase subunit 30A (Cks30A) encodes a protein that promotes progression through female meiosis and the mitotic divisions of the early embryo. It interacts with the product of Cdk1 and is required in prometaphase for spindle assembly, and at the metaphase to anaphase transition for the destruction of the cyclin encoded by CycA. [Date last reviewed: 2019-03-21]
FBgn0010315	CycD	Cyclin D	Cyclin D (CycD) encodes a protein that binds to the product of Cdk4, thereby promoting its kinase activity. The CycD-Cdk4 complex promotes cell growth and progression through the G1 phase - it phosphorylates and thereby inhibits the product of Rbf, the ortholog of the human tumor suppressor retinoblastoma protein. [Date last reviewed: 2018-09-13]
FBgn0010316	dap	dacapo	dacapo (dap) encodes a Cyclin-dependent kinase inhibitor in the CIP/KIP family. It binds to CycE-Cdk2 complexes and thereby inhibits their protein kinase activity. Upregulation of dap is required after the last mitosis for arresting cells in G1/G0 before terminal differentiation in many post-mitotic cell types. [Date last reviewed: 2019-03-07]
FBgn0010328	woc	without children	without children (woc) encodes a chromatin-binding factor related to the mammalian MYM-type family of transcription factors. It is involved in telomere capping, regulation of transcription, ecdysone biosynthesis and germline stem cell differentiation. [Date last reviewed: 2019-03-21]
FBgn0010329	Tbh	Tyramine beta hydroxylase	Tyramine β hydroxylase (Tbh) encodes a monooxygenase and the key limiting enzyme in octopamine synthesis. It regulates egg laying, positive associative olfactory learning and memory, aggression, flight initiation and maintenance, locomotor activity and attraction to ethanol containing food sources. [Date last reviewed: 2019-03-14]
FBgn0010333	Rac1	Rac1	NA
FBgn0010339	128up	upstream of RpIII128	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0010340	140up	upstream of RpII140	NA
FBgn0010341	Cdc42	Cdc42	Cdc42 (Cdc42) encodes a GTPase signaling protein that acts as a molecular switch and functions as key regulator of the actin cytoskeleton. It plays a central role in diverse biological processes including actin cytoskeleton organization, mophogenesis, hemocyte migration, cell polarity, and wound repair. [Date last reviewed: 2019-03-07]
FBgn0010342	Map60	Microtubule-associated protein 60	Microtubule-associated protein 60 (Map60) encodes a microtubule binding protein that, together with gamma-tubulin and the product of Cp190, is a component of a centrosomal complex that can interact with microtubules. [Date last reviewed: 2019-03-14]
FBgn0010348	Arf79F	ADP ribosylation factor at 79F	NA
FBgn0010350	Cds	CDP-diacylglycerol synthase	CDP-diacylglycerol synthase (Cds) encodes an enzyme for the synthesis of cytidine diphosphate diacylglycerol (CDP-DAG) from phosphatidic acid. CDP-DAG is the precursor of two phospholipids, phosphatidylinositol and phosphatidylglycerol. The product of Cds has roles in cell growth and lipid storage. [Date last reviewed: 2019-03-07]
FBgn0010352	Ogdh	Oxoglutarate dehydrogenase	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0010355	Taf1	TBP-associated factor 1	TBP-associated factor 1 (Taf1) encodes a component of the evolutionarily conserved general transcription factor TFIID. It regulates transcription by binding the initiator element at transcription start sites and binding acetylated histones via its bromodomains. [Date last reviewed: 2019-03-14]
FBgn0010356	Taf5	TBP-associated factor 5	TBP-associated factor 5 (Taf5) encodes a protein that forms part of the multisubunit basal transcription factor TFIID and it may be important for its assembly or stability. [Date last reviewed: 2019-03-14]
FBgn0010379	Akt	Akt kinase	Akt kinase (Akt) encodes the core kinase component of the insulin/insulin-like growth factor pathway. It functions downstream of the product of Pi3K92E and is activated by phosphatidylinositol binding and phosphorylation. It regulates cell growth and survival, stress responses and ageing. [Date last reviewed: 2019-03-07]
FBgn0010380	AP-1-2beta	Adaptor Protein complex 1/2, beta subunit	Adaptor Protein complex 1/2, β subunit (AP-1-2β) encodes a clathrin adaptor involved in vesicle trafficking and autophagy regulation. [Date last reviewed: 2019-07-11]
FBgn0010382	CycE	Cyclin E	NA
FBgn0010388	Dro	Drosocin	Drosocin (Dro) encodes an o-Glycosylated antibacterial peptide with activity against Gram-negative and Gram-positive bacteria. It is expressed in the fat body during the systemic immune response and is expressed in various epithelia. The expression of Dro is regulated at the transcriptional level mostly by the immune deficiency pathway. [Date last reviewed: 2019-03-07]
FBgn0010391	SrpRalpha	Signal recognition particle receptor alpha	NA
FBgn0010395	Itgbn	Integrin betanu subunit	NA
FBgn0010397	LamC	Lamin C	Lamin C (LamC) encodes a type V intermediate filament that is essential for development. It contributes to the shape and structural integrity of the nucleus and plays roles in genome integrity and gene regulation, through contacts made with chromatin. [Date last reviewed: 2019-03-14]
FBgn0010398	Lrr47	Leucine-rich repeat 47	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0010406	RNaseX25	Ribonuclease X25	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0010407	Ror	Ror	Ror (Ror) encodes a transmembrane receptor tyrosine kinase structurally related to vertebrate neural-specific Wnt-binding Ror receptors. It is primarily expressed in the nervous system and it is likely to signal through the ERK MAP kinase pathway. [Date last reviewed: 2018-09-13]
FBgn0010408	RpS9	Ribosomal protein S9	Ribosomal protein S9 (RpS9) encodes a structural constituent of ribosomes. [Date last reviewed: 2019-07-11]
FBgn0010409	RpL18A	Ribosomal protein L18A	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0010411	RpS18	Ribosomal protein S18	Ribosomal protein S18 (RpS18) encodes a ribosomal protein located at the top of the head of the 40S subunit and contacts several helices of the 18S rRNA. [Date last reviewed: 2018-09-13]
FBgn0010412	RpS19a	Ribosomal protein S19a	Ribosomal protein S19a (RpS19a) encodes a structural constituent of ribosomes. [Date last reviewed: 2019-07-11]
FBgn0010415	Sdc	Syndecan	Syndecan (Sdc) encodes a transmembrane heparan sulfate proteoglycan. It binds to the products of sli and robo1 to regulate axon guidance at the CNS midline, and it cooperates with the product of Lar to promote synapse growth at the larval neuromuscular junction. [Date last reviewed: 2019-03-14]
FBgn0010416	TH1	TH1	TH1 (TH1) encodes one of four subunits that constitutes the NELF complex. The NELF complex along with DSIF causes RNA polymerase II to pause 20 to 50 nucleotides downstream from the transcription start site of most and possibly all actively transcribed genes in a process commonly called promoter proximal pausing. [Date last reviewed: 2019-03-14]
FBgn0010417	Taf6	TBP-associated factor 6	TBP-associated factor 6 (Taf6) encodes a protein that forms part of the multisubunit basal transcription factor TFIID, and it might be important for its stability. It forms a histone-like pair with the product of e(y)1. It is required during all stages of development, but particularly during imaginal disc development and gametogenesis. [Date last reviewed: 2019-03-14]
FBgn0010421	TfIIFbeta	Transcription factor TFIIFbeta	NA
FBgn0010422	TfIIS	RNA polymerase II elongation factor	NA
FBgn0010434	cora	coracle	NA
FBgn0010435	emp	epithelial membrane protein	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0010438	mtSSB	mitochondrial single stranded DNA-binding protein	NA
FBgn0010441	pll	pelle	Pelle (pll) encodes a tyrosine kinase-like family serine-threonine protein kinase that functions in the Toll pathway, a signaling cascade that plays key roles in various developmental and immune processes, notably embryonic dorso-ventral patterning and regulation of antimicrobial peptide production. [Date last reviewed: 2016-06-30]
FBgn0010470	Fkbp14	FK506-binding protein 14	FK506-binding protein 14 (Fkbp14) encodes an ER resident protein and a member of the large FKBP family of immunophilins. It plays an essential role in development, including stabilizing the protein encoded by Psn in the ER. Fkbp14 mutants genetically interact with components of the Notch pathway. [Date last reviewed: 2018-09-13]
FBgn0010488	NAT1	NAT1	NAT1 (NAT1) encodes a protein involved in chaeta development. [Date last reviewed: 2019-09-19]
FBgn0010497	dmGlut	Dietary and metabolic glutamate transporter	Dietary and metabolic glutamate transporter (dmGlut) encodes a sodium-independent transmembrane glutamate transporter. It plays an essential role during early embryogenesis. It causes megamitochondria formation when it is overexpressed. [Date last reviewed: 2019-03-07]
FBgn0010501	Dcp-1	Death caspase-1	Death caspase-1 (Dcp-1) encodes an effector caspase that cleaves specific proteins during apoptosis. It typically acts downstream of the initiator caspase encoded by Dronc. It is also involved in non-apoptotic processes such as autophagy. [Date last reviewed: 2019-03-07]
FBgn0010504	kermit	kermit	kermit (kermit) encodes a GIPC (GAIP interacting protein, C terminus) type protein. It interacts with the product of Gyc76C, facilitating neuron axon guidance in a process mediated by the product of PlexA. It also physically and genetically interacts with the product of jar during wing planar cell polarity establishment. It is required for locomotive activity and determination of lifespan. [Date last reviewed: 2019-03-14]
FBgn0010516	wal	walrus	walrus (wal) encodes a protein involved in the development of Malpighian tubules, gut and trachea. [Date last reviewed: 2019-08-01]
FBgn0010520	Bka	Bekka	NA
FBgn0010531	Ccs	Copper chaperone for superoxide dismutase	Copper chaperone for superoxide dismutase (Ccs) encodes a protein required for the proper superoxide dismutase function of the product of Sod1. It is involved in determination of lifespan, oxidative stress, and cytosolic aconitase activity. [Date last reviewed: 2019-03-07]
FBgn0010548	Aldh-III	Aldehyde dehydrogenase type III	Aldehyde dehydrogenase type III (Aldh-III) encodes a protein that confers a xenobiotic stress resistance by oxidising aromatic aldehydes (benzaldehyde). It also neutralises the lipid aldehydes formed after the attack of reactive oxygen and radicals, such as malondialdehyde during lipid peroxidation. The catalytic redox reaction uses NAD(P)+ as a cofactor. [Date last reviewed: 2019-03-07]
FBgn0010549	l(2)03659	lethal (2) 03659	NA
FBgn0010551	Phb2	Prohibitin 2	NA
FBgn0010583	dock	dreadlocks	NA
FBgn0010590	Prosbeta1	Proteasome beta1 subunit	NA
FBgn0010591	Sply	Sphingosine-1-phosphate lyase	NA
FBgn0010602	lwr	lesswright	lesswright (lwr) encodes Ubc9, a SUMO conjugating enzyme that accepts SUMO from the SUMO activating enzyme and hands it off to the SUMO conjugation target. It has documented biological functions in innate immunity, meiosis, and anterior patterning of the embryo. [Date last reviewed: 2019-03-14]
FBgn0010607	l(2)05714	lethal (2) 05714	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0010611	Hmgs	HMG Coenzyme A synthase	NA
FBgn0010612	ATPsynG	ATP synthase, subunit G	ATP synthase, subunit G (ATPsynG) encodes a subunit in the F0 portion of mitochondrial ATP synthase (Complex V). ATP synthase catalyzes the formation of ATP using energy from a proton gradient across the inner mitochondrial membrane after electron transport. [Date last reviewed: 2018-09-13]
FBgn0010621	CCT5	Chaperonin containing TCP1 subunit 5	Chaperonin containing TCP1 subunit 5 (CCT5) encodes a component of the TCP-1 ring complex (TRiC) chaperonin. It is involved in myofibril organization maintenance, cardiac physiological rhythm and lifespan determination. [Date last reviewed: 2019-09-12]
FBgn0010622	DCTN3-p24	Dynactin 3, p24 subunit	NA
FBgn0010638	Sec61beta	Sec61 beta subunit	Sec61 β subunit (Sec61β) encodes a protein involved in the regulation of autophagy. [Date last reviewed: 2019-09-19]
FBgn0010651	MFS14	Major Facilitator Superfamily Transporter 14	Major Facilitator Superfamily Transporter 14 (MFS14) encodes a protein involved in response to hypoxia. [Date last reviewed: 2019-09-12]
FBgn0010660	Nup214	Nucleoporin 214kD	NA
FBgn0010741	Pfdn2	Prefoldin 2	NA
FBgn0010747	Srp54k	Signal recognition particle 54k	NA
FBgn0010750	atms	antimeros	antimeros (atms) encodes a component of the PAF1 complex (together with the products of Atu, hyx, Rtf1 and Ctr9). The PAF1 complex physically interacts with components of the basal transcription machinery and sequence-specific transcription factors to control histone modifications and pause release. [Date last reviewed: 2018-09-13]
FBgn0010762	simj	simjang	simjang (simj) encodes a component of the NURD complex, which couples chromatin remodelling and histone deacetylation to mediate transcriptional repression. The product of simj is involded in cardiogenesis and habituation. [Date last reviewed: 2019-08-01]
FBgn0010768	sqz	squeeze	squeeze (sqz) encodes a transcription factor that regulates neuropeptidergic cellular identity and axon/dendrite pathfinding. [Date last reviewed: 2019-03-14]
FBgn0010770	ppan	peter pan	NA
FBgn0010772	Xe7	Xe7	Xe7 (Xe7) encodes a protein that contributes to axon guidance and lateral inhibition. [Date last reviewed: 2019-03-21]
FBgn0010774	Ref1	RNA and export factor binding protein 1	NA
FBgn0010786	l(3)02640	lethal (3) 02640	NA
FBgn0010803	TrpRS	Tryptophanyl-tRNA synthetase	Tryptophanyl-tRNA synthetase (TrpRS) is expressed to high levels in the salivary gland. This could be incidental due to proximity to the salivary gland transcription factor encoded by sage. [Date last reviewed: 2019-03-14]
FBgn0010808	Chchd3	Coiled-coil-helix-coiled-coil-helix domain containing 3	Coiled-coil-helix-coiled-coil-helix domain containing 3 (Chchd3) encodes a mitochondrial inner membrane protein that is required for mitochondrial fusion. Loss of Chchd3 leads to inactivation of Hippo activity, decreased tissue growth, cell proliferation defects, oxidative stress and JNK pathway activation. [Date last reviewed: 2019-03-07]
FBgn0010812	unc-45	uncoordinated 45	uncoordinated 45 (unc-45) encodes a protein that binds the product of Hsp83 and myosin, and may may serve as a scaffold for their interaction. It is required for normal myosin accumulation and appears to play a role in myosin folding and/or protection from stress. [Date last reviewed: 2019-03-21]
FBgn0010825	Gug	Grunge	Grunge (Gug) encodes a nuclear repressor protein that likely responds to Egfr signaling to control cell behavior for normal developmental patterning. [Date last reviewed: 2019-03-07]
FBgn0010830	l(3)04053	lethal (3) 04053	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0010877	l(3)05822	lethal (3) 05822	NA
FBgn0010894	sinu	sinuous	sinuous (sinu) encodes a claudin that contributes to the assembly of septate junctions. It is involved in the development of heart, tracheal tree and the glial blood-brain barrier. [Date last reviewed: 2019-09-26]
FBgn0010905	Spn	Spinophilin	Spinophilin (Spn) encodes a scaffold protein protein that regulates the neurexin/neuroligin signalling at the presynaptic active zone. [Date last reviewed: 2019-09-19]
FBgn0010909	msn	misshapen	misshapen (msn) encodes a Sterile 20 MAP kinase kinase kinase. [Date last reviewed: 2019-03-14]
FBgn0010926	l(3)07882	lethal (3) 07882	NA
FBgn0011016	SsRbeta	Signal sequence receptor beta	NA
FBgn0011020	Sas-4	Spindle assembly abnormal 4	Spindle assembly abnormal 4 (Sas-4) encodes a centriole protein that is essential for centriole assembly. It is recruited to centrioles through an interaction with the centriole protein encoded by ana2, and it helps recruit microtubules to the centriole. [Date last reviewed: 2019-03-14]
FBgn0011202	dia	diaphanous	diaphanous (dia) encodes the sole Dia-class formin in Drosophila. It nucleates actin filaments de novo and acts as a processive actin polymerase, stimulating actin addition at the barbed end. It plays an essential role in cytokinesis and also regulates cell shape change and protrusion. [Date last reviewed: 2019-03-07]
FBgn0011204	cue	cueball	NA
FBgn0011205	fbl	fumble	fumble (fbl) encodes an enzyme that phosphorylates pantothenate (vitamin B5), which is one of the early steps of the Coenzyme A de novo biosynthesis pathway. [Date last reviewed: 2019-03-07]
FBgn0011206	bol	boule	boule (bol) encodes a translational regulator required in spermatogenesis for entry into meiosis and spermatid differentiation. It has an additional role in mushroom body γ neurons as a negative regulator of axon pruning. [Date last reviewed: 2019-03-07]
FBgn0011207	pelo	pelota	NA
FBgn0011211	blw	bellwether	bellwether (blw) encodes the alpha subunit of the mitochondrial F1F0 ATP synthase complex (complex V), the final enzyme of the oxidative phosphorylation pathway. Complex V catalyzes the synthesis of ATP from ADP and inorganic phosphate using the electrochemical proton gradient across the inner mitochondrial membrane. [Date last reviewed: 2018-09-13]
FBgn0011217	eff	effete	effete (eff) encodes a conserved class I E2 ubiquitin-conjugating enzyme that contributes to the protein ubiquitination and degradation pathway. The roles of the product of eff include female germline stem cell maintenance, eye development, apoptosis regulation and chromatin organization. [Date last reviewed: 2019-03-07]
FBgn0011224	heph	hephaestus	hephaestus (heph) encodes a nucleo-cytoplasmic shuttling protein that regulates osk mRNA translation. It is involved in spermatid individualization and Notch signalling regulation. [Date last reviewed: 2019-09-19]
FBgn0011225	jar	jaguar	NA
FBgn0011227	ox	oxen	NA
FBgn0011230	poe	purity of essence	purity of essence (poe) encodes a Calmodulin-binding, E3 ubiquitin ligase. It functions in glial growth in peripheral nerves, motor neuron excitability, synaptic vesicle release and sperm individuation. [Date last reviewed: 2019-03-14]
FBgn0011232	scat	scattered	NA
FBgn0011236	ken	ken and barbie	ken and barbie (ken) encodes a transcription factor involved in genital formation. [Date last reviewed: 2019-03-14]
FBgn0011259	Sema1a	Semaphorin 1a	Semaphorin 1a (Sema1a) encodes a transmembrane protein belonging to the semaphorin protein family. It is a repulsive axon guidance cue, signaling through direct interactions with the receptor encoded by PlexA, and also functions as a receptor to regulate dendrite targeting and axon guidance. Secreted semaphorins encoded by Sema2a and Sema2b can act as the product of Sema1a ligands. [Date last reviewed: 2019-03-14]
FBgn0011260	Sema2a	Semaphorin 2a	Semaphorin 2a (Sema2a) encodes a secreted member of the semaphorin protein family. It utilizes the receptor encoded by PlexB to mediate both repulsive and attractive axon guidance. It also utilizes the transmembrane semaphorin encoded by Sema1a as a receptor for dendrite process guidance. [Date last reviewed: 2019-03-14]
FBgn0011272	RpL13	Ribosomal protein L13	Ribosomal protein L13 (RpL13) encodes a ribosomal structural constituent. [Date last reviewed: 2019-07-11]
FBgn0011274	Dif	Dorsal-related immunity factor	Dorsal-related immunity factor (Dif) encodes a transcription factor that contributes to zygotic function of the Toll pathway, notably the regulation of antimicrobial peptides, but it is not involved in dorsoventral patterning of the embryo. [Date last reviewed: 2019-03-07]
FBgn0011284	RpS4	Ribosomal protein S4	Ribosomal protein S4 (RpS4) encodes a structural constituent of ribosomes. [Date last reviewed: 2019-07-11]
FBgn0011289	TfIIA-L	Transcription factor IIA L	Transcription factor IIA L (TfIIA-L) encodes a precursor protein that, after proteolysis, produces the two larger subunits of TFIIA. TFIIA is a general transcription factor that is required for initiation by RNA polymerase II and is a component of the pre-initiation complex. [Date last reviewed: 2018-09-13]
FBgn0011290	Taf12	TBP-associated factor 12	TBP-associated factor 12 (Taf12) encodes a protein that forms part of the multisubunit basal transcription factor TFIID, and it is important for its stability. It forms a histone-like pair with Taf4. Taf12 is also an integral component of the Drosophila SAGA histone acetyltransferase complex. [Date last reviewed: 2019-03-14]
FBgn0011291	Taf11	TBP-associated factor 11	TBP-associated factor 11 (Taf11) encodes a protein that forms part of the multisubunit basal transcription factor TFIID. It enhances RNA interference efficiency, organizing the assembly of the RISC loading complex. [Date last reviewed: 2019-03-14]
FBgn0011297	Alg3	ALG3, alpha-1,3- mannosyltransferase	NA
FBgn0011300	babo	baboon	baboon (babo) encodes the type I receptor for the activin-like ligands encoded by daw, Actβ and myo. There are three isoforms of the product of babo that differ only in their extracellular domain likely resulting in different ligand binding specificity. It can form a complex with the type II receptors put or wit in the presence of an activin like ligand. This results in the transcriptional regulation of activin responsive genes. [Date last reviewed: 2019-03-07]
FBgn0011305	Rsf1	Repressor splicing factor 1	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0011327	Uch-L5	Ubiquitin carboxy-terminal hydrolase L5	Ubiquitin carboxy-terminal hydrolase L5 (Uch-L5) encodes a component of the 26S proteasome, which degrades polyubiquitinated proteins in the cytoplasm and nucleus. [Date last reviewed: 2019-08-01]
FBgn0011335	vers	versatile	versatile (vers) encodes a component of the heterochromatin protein 1 complex that regulates adult testis germline stem cell fate. [Date last reviewed: 2019-06-06]
FBgn0011336	Stt3B	Catalytic subunit 3B of the oligosaccharyltransferase complex	NA
FBgn0011361	ND-ACP	NADH dehydrogenase (ubiquinone) acyl carrier protein	NA
FBgn0011455	ND-SGDH	NADH dehydrogenase (ubiquinone) SGDH subunit	NADH dehydrogenase (ubiquinone) SGDH subunit (ND-SGDH) encodes a protein required for proper mitochondrial electron transport chain function. It is involved in longevity and redox response. [Date last reviewed: 2019-09-26]
FBgn0011474	PR-Set7	PR/SET domain containing protein 7	PR/SET domain containing protein 7 (PR-Set7) encodes the histone methyltransferase that controls lysine20 monomethylation of the product of His4. This histone mark is essential for normal progression through the cell cycle. [Date last reviewed: 2019-03-14]
FBgn0011476	l(3)neo43	lethal (3) neo43	NA
FBgn0011481	Ssdp	Sequence-specific single-stranded DNA-binding protein	Sequence-specific single-stranded DNA-binding protein (Ssdp) encodes a DNA binding protein. It has been proposed to be an additional component of ap/Chi transcriptional complexes because it interacts with the product of Chi and lack of Ssdp produces defects similar to ap or Chi mutant phenotypes. [Date last reviewed: 2019-03-14]
FBgn0011509	SrpRbeta	Signal recognition particle receptor beta	Signal recognition particle receptor β (SrpRβ) encodes a protein that contributes to cuticle secretion by epidermal cells. [Date last reviewed: 2019-03-14]
FBgn0011566	Smyd3	SET and MYND domain containing, class 3	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0011570	cpb	capping protein beta	capping protein beta (cpb) encodes an actin-binding protein that, together with cpa, binds to the fast growing ends of actin filaments, restricting the addition or loss of actin monomers. It restricts JNK signaling, modulates Hippo signaling, maintains epithelial integrity and neuronal homeostasis, controls proliferation/apoptosis in wing imaginal discs, and promotes oogenesis. [Date last reviewed: 2018-09-13]
FBgn0011573	Cdc37	Cdc37	Cdc37 (Cdc37) encodes a putative chaperone that inhibits Wnt and Hh signaling pathways. [Date last reviewed: 2018-09-13]
FBgn0011576	Cyp4d2	Cytochrome P450 4d2	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0011584	Trp1	Translocation protein 1	NA
FBgn0011586	e(r)	enhancer of rudimentary	NA
FBgn0011591	fng	fringe	fringe (fng) encodes a glycosyltransferase that modifies EGF domains of the product of N. This glycosylation enhances the interactions the product of N with its ligand encoded by Dl, and inhibits those with its ligand encoded by Ser. In this way the product of fng modulates Notch signaling. [Date last reviewed: 2019-03-07]
FBgn0011592	fra	frazzled	frazzled (fra) encodes a DCC-like Netrin receptor that mediates axon guidance. It also contributes to dendrite guidance, development and morphogenesis. [Date last reviewed: 2019-03-07]
FBgn0011596	fzo	fuzzy onions	fuzzy onions (fzo) encodes an evolutionarily conserved transmembrane Dynamin-type GTPase and founder member of the mitofusin class of proteins. It is required for proper fusion of mitochondria during spermatid differentiation to form the Nebenkern mitochondrial formation. [Date last reviewed: 2019-03-07]
FBgn0011604	Iswi	Imitation SWI	NA
FBgn0011606	Klp3A	Kinesin-like protein at 3A	Kinesin-like protein at 3A (Klp3A) encodes a microtubule motor protein involved in chromosome segregation and mitotic spindle morphogenesis. [Date last reviewed: 2019-07-11]
FBgn0011638	La	La autoantigen-like	NA
FBgn0011640	lark	lark	lark (lark) encodes an essential RNA-binding protein of the RNA recognition motif (RRM) class. It is implicated in both RNA splicing and translational control. It contributes to oogenesis, tissue development and circadian behavior. [Date last reviewed: 2019-03-14]
FBgn0011642	Zyx	Zyxin	Zyxin (Zyx) encodes an actin cytoskeleton regulator found at cell-matrix junctions and cell-cell adherens junctions. Its roles include mechanotransduction and regulation of the Hippo signaling pathway. [Date last reviewed: 2019-03-21]
FBgn0011648	Mad	Mothers against dpp	Mothers against dpp (Mad) encodes the primary transcription factor that mediates cellular response to the BMP like ligands encoded by dpp, scw and gbb. Upon phosphorylation by either the products of sax or tkv (type I BMP receptors), it forms a complex with the product of Med and translocates to the nucleus where, together with cofactors, it regulates expression of BMP response target genes. [Date last reviewed: 2019-03-14]
FBgn0011655	Med	Medea	Medea (Med) encodes a protein that belongs to the highly conserved Smad family. It can bind its siblings encoded by Mad or Smox to facilitate signal transduction for the product of dpp or Activin ligands in the TGF-beta family. Med-complexes function as transcriptional regulators. Many developmental roles include dorsal-ventral patterning, patterning and proliferation of the wing disc and gene expression in the mushroom body of the larval brain. [Date last reviewed: 2019-03-14]
FBgn0011656	Mef2	Myocyte enhancer factor 2	Myocyte enhancer factor 2 (Mef2) encodes a protein that belongs to the MADS-box family of transcription factors and is required for muscle development. It directly activates a large number of muscle protein genes. It also regulates gene expression in other tissues, including the fat body and neural tissue. [Date last reviewed: 2019-03-14]
FBgn0011659	Mlh1	Mlh1	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0011660	Pms2	Pms2	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0011661	Moe	Moesin	Moesin (Moe) encodes an Ezrin, Radixin, Moesin (ERM) protein involved in cortical cytoskeleton stability. It regulates the products of crb and Rho1. The product of Moe contributes to apical-basal polarity, mitotic spindle organisation and epithelial integrity. [Date last reviewed: 2019-03-14]
FBgn0011666	msi	musashi	musashi (msi) encodes an RNA binding protein that binds to the 3' UTR region of target mRNAs, including ttk and sima, thus it positively regulates neural differentiation and negatively regulates the HIF pathway. It contributes to cell fate determination, as well as cellular response to normoxic/hypoxic conditions. [Date last reviewed: 2019-03-14]
FBgn0011672	Mvl	Malvolio	Malvolio (Mvl) encodes a member of the SLC11 family of metal ion transporters that transports divalent metal cations, including Mn[2+] and Fe[2+]. Its function has been linked to feeding-related decisions, possibly via modulation of dopaminergic signaling. [Date last reviewed: 2018-09-13]
FBgn0011674	insc	inscuteable	inscuteable (insc) encodes an adaptor protein required for asymmetric cell division. It interacts with the microtubule binding protein encoded by mud and the adaptor encoded by pins. It also binds to the apical complex proteins encoded by baz, par-6 and aPKC and may recruit microtubule binding proteins to the apical cell cortex to induce apical-basal spindle orientation. [Date last reviewed: 2019-03-07]
FBgn0011676	Nos	Nitric oxide synthase	NA
FBgn0011692	pav	pavarotti	pavarotti (pav) encodes a microtubule motor protein from the Kinesin superfamily. It plays important roles during the mitotic cycle including spindle formation, cortical cytoskeleton reorganization and cytokinesis. It also negatively regulates Wnt activity. [Date last reviewed: 2019-06-13]
FBgn0011703	RnrL	Ribonucleoside diphosphate reductase large subunit	NA
FBgn0011704	RnrS	Ribonucleoside diphosphate reductase small subunit	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0011705	rost	rolling stone	NA
FBgn0011708	Syx5	Syntaxin 5	Syntaxin 5 (Syx5) encodes a type II transmembrane protein in the Q-SNARE family that forms hetero tetramers required for membrane function in the early secretory pathway (ER and Golgi). It has been involved in cytokinesis during spermatogenesis. [Date last reviewed: 2019-03-14]
FBgn0011710	Septin1	Septin 1	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0011715	Snr1	Snf5-related 1	Snf5-related 1 (Snr1) encodes a core component of the ATP-dependent SWI/SNF chromatin-remodeling complex (Brahma complex). It functions as a tumor suppressor and is required for maintaining normal endosomal trafficking-mediated signaling cascades. [Date last reviewed: 2018-09-13]
FBgn0011722	Tig	Tiggrin	Tiggrin (Tig) is an extracellular matrix protein and integrin ligand that accumulates at the embryonic and larval muscle attachment site. It is also found as a component of the hemolymph clot. [Date last reviewed: 2018-09-13]
FBgn0011725	twin	twin	twin (twin) encodes the CCR4 deadenylase, one of two enzymes in the CCR4-NOT complex that degrade mRNA poly(A) tails. It is required during oogenesis in germline stem cell self-renewal, synchronous germ cell division and prevention of cell death, as well as in early embryonic patterning through the deadenylation of specific maternal mRNAs. [Date last reviewed: 2018-09-13]
FBgn0011726	tsr	twinstar	NA
FBgn0011737	Wee1	Wee1 kinase	Wee1 kinase (Wee1) encodes a tyrosine kinase required for triggering entry into mitosis. The activity of the Wee1 product contributes to spindle assembly and alignment and separation of the chromosomes. [Date last reviewed: 2019-03-21]
FBgn0011739	wts	warts	warts (wts) encodes a tumor suppressor kinase in the Hippo pathway involved in the control of tissue growth. It also plays a post-mitotic role in R8 photoreceptor cells where it antagonizes the product of melt to control the bistable choice of Rhodospin expression. [Date last reviewed: 2019-03-21]
FBgn0011740	alpha-Man-IIa	alpha-Mannosidase class II a	NA
FBgn0011741	Arp6	Actin-related protein 6	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0011742	Arp2	Actin-related protein 2	Actin-related protein 2 (Arp2) encodes one of the actin-related proteins within the Arp2/3 complex, which is the basic actin nucleator of eukaryotes. [Date last reviewed: 2018-09-13]
FBgn0011745	Arp1	Actin-related protein 1	Actin-related protein 1 (Arp1) encodes the short filamentous component of the Dynactin complex, which plays an essential role in the activation of the Dynein microtubule motor protein. As such, the Arp1 product is required for diverse cellular processes such as intracellular transport, mitotic spindle assembly, chromosome movements, and nuclear positioning. [Date last reviewed: 2018-09-13]
FBgn0011747	Ank	Ankyrin	Ankyrin (Ank) encodes protein that is recruited to the plasma membrane by its association with the product of β-Spec. It also binds to the adhesion protein encoded by Nrg leading to accumulation of the products of Ank and β-Spec at sites of cell-cell adhesion. [Date last reviewed: 2019-03-07]
FBgn0011754	PhKgamma	Phosphorylase kinase gamma	Phosphorylase kinase γ (PhKγ) encodes a protein involved in gastrulation, embryonic mesoderm formation and adult leg musculature development. [Date last reviewed: 2019-08-01]
FBgn0011760	ctp	cut up	cut up (ctp) encodes the 8 kDa (LC8/DLC1) subunit of the cytoplasmic Dynein, as well as the Myosin V. It homodimerizes and binds to a variety of proteins. It is involved in both dynein-dependent and independent functions such as cell viability, axonal guidance, spermatid growth and individualization, and regulation of spermatogonial divisions. [Date last reviewed: 2019-03-07]
FBgn0011762	Prim1	DNA primase subunit 1	DNA primase subunit 1 (Prim1) encodes a subunit of the DNA-polymerase alpha complex that, together with the subunit encoded by Prim2, is responsible for primase activity (synthesis of short RNA primers). This activity is required during DNA replication to prime DNA synthesis at origins, and also on the lagging strand during Okazaki fragment synthesis. [Date last reviewed: 2019-09-26]
FBgn0011763	Dp	DP transcription factor	DP transcription factor (Dp) encodes a member of the DREAM complex and the common subunit of the two Drosophila heterodimeric E2F transcription factors. It is regulated by the product of Rbf and the Cyclin dependent kinases and controls the transcription of genes necessary for cell cycle progression. [Date last reviewed: 2019-03-07]
FBgn0011766	E2f1	E2F transcription factor 1	NA
FBgn0011768	Fdh	Formaldehyde dehydrogenase	Formaldehyde dehydrogenase (Fdh) encodes a medium-chain alcohol dehydrogenase. This enzyme also functions as S-nitrosoglutathione reductase during the nitric oxide metabolism, contributing to visual memory. [Date last reviewed: 2019-03-07]
FBgn0011769	Fdx1	Ferredoxin 1	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0011770	Gip	GIP-like	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0011771	Hem	HEM-protein	HEM-protein (Hem) encodes a component of the WAVE Regulatory Complex. Hem product regulates processes such as neuronal migration and asymmetric division of neural precursors by inhibiting the product of SCAR degradation. In the asymmetric process, the Hem-pathway indirectly maintains proper localization of proteins such as those encoded by insc and numb. [Date last reviewed: 2019-03-21]
FBgn0011774	Irbp	Inverted repeat-binding protein	Inverted repeat-binding protein (Irbp) encodes a protein that, together with the product of Ku80, forms part of the Ku protein complex, which is involved in double-strand break repair via non-homologous end joining and telomere maintenance. [Date last reviewed: 2018-09-13]
FBgn0011785	BRWD3	BRWD3	BRWD3 (BRWD3) encodes a member of the Bromodomain and WD repeat_containing protein (BRWD) family. It regulates ecdysone and JAK-STAT signaling pathways and contributes to eye development, cell death and phagocytosis. [Date last reviewed: 2019-03-07]
FBgn0011787	mRpL12	mitochondrial ribosomal protein L12	mitochondrial ribosomal protein L12 (mRpL12) encodes a protein required for Cyclin D/Cdk4-driven cell growth. [Date last reviewed: 2019-07-11]
FBgn0011802	Gem3	Gemin 3	Gemin 3 (Gem3) encodes an RNA helicase and a member of the SMN-Gemins complex. It is a component of the cytoplasmic U snRNP body and nuclear gems. It is required in the motor system for viability, neuromuscular junction development and motor behaviour. [Date last reviewed: 2019-09-26]
FBgn0011817	nmo	nemo	nemo (nmo) encodes an atypical proline-directed serine/threonine kinase with roles in numerous developmental processes, including ommatidial rotation/planar cell polarity, retinal specification and neuronal function, and circadian clock speed. It regulates the activity of several signal transduction pathways, including BMP, Wnt, and Notch, and is implicated in fly models of neurodegenerative diseases. [Date last reviewed: 2019-03-14]
FBgn0011818	oaf	out at first	NA
FBgn0011824	CG4038	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0011826	Pp2B-14D	Protein phosphatase 2B at 14D	NA
FBgn0011828	Pxn	Peroxidasin	NA
FBgn0011829	Ret	Ret oncogene	Ret oncogene (Ret) encodes a cell surface receptor mediating dendrite development of class IV dendritic arborization sensory neurons. It interacts with integrins and mediates rac1 signaling to promote dendrite adhesion to the extracellular matrix. [Date last reviewed: 2019-03-14]
FBgn0011836	Taf2	TBP-associated factor 2	TBP-associated factor 2 (Taf2) encodes a protein that forms part of the multisubunit basal transcription factor TFIID. Together with the product of Taf1, it binds the Initiator and/or the DPE core promoter elements. [Date last reviewed: 2019-03-14]
FBgn0011837	Tis11	Tis11 zinc finger protein	Tis11 zinc finger protein (Tis11) encodes a protein with three splice isoforms, all of which have the major attributes of members of the tristetraprolin (TTP) family of RNA binding and destabilizing proteins. Tis11 knockout and knock-down flies exhibit relatively minor delays in eclosion associated with accumulation of many putative mRNA targets. [Date last reviewed: 2019-03-14]
FBgn0012034	AcCoAS	Acetyl Coenzyme A synthase	NA
FBgn0012036	Aldh	Aldehyde dehydrogenase	Aldehyde dehydrogenase (Aldh) encodes an NAD[+] dependent mitochondrial aldehyde dehydrogenase. Its functions include detoxifying endogenous aldehydes generated by lipid peroxidation, and detoxifying acetaldehyde derived from dietary ethanol. [Date last reviewed: 2019-03-07]
FBgn0012037	Ance	Angiotensin converting enzyme	Angiotensin converting enzyme (Ance) encodes a member of the peptidyl-dipeptidase A family of zinc metallopeptidases. Ance product is an extracellular glycosylated enzyme with a broad substrate specificity, cleaving dipeptides from the carboxy terminus of oligopeptides. [Date last reviewed: 2018-09-13]
FBgn0012051	CalpA	Calpain-A	Calpain-A (CalpA) encodes a calcium-dependent modulatory protease that cleaves its substrates in a limited fashion. During patterning and division in the blastoderm embryo, CalpA product cleaves the NF-κB inhibitor and the cell cycle regulator encoded by cact and CycB, respectively. CalpA product also regulates dendritic prunning of sensory neurons. [Date last reviewed: 2018-09-13]
FBgn0012058	Cdc27	Cell division cycle 27	Cell division cycle 27 (Cdc27) encodes a component of the anaphase-promoting complex/cyclosome (APC/C). It is important for substrate recruitment and interacts with its co-activators, encoded by fzy and fzr, as well as the mitotic checkpoint proteins, encoded by mad2 and BubR1. [Date last reviewed: 2019-03-07]
FBgn0013263	Trl	Trithorax-like	Trithorax-like (Trl) encodes a GAGA transcription factor involved in chromatin modification. It contributes to cell division, dosage compensation and gametogenesis. [Date last reviewed: 2019-03-14]
FBgn0013269	Fkbp39	FK506-binding protein 39kD	FK506-binding protein 39kD (Fkbp39) encodes a protein thay acts as an inhibitor of autophagy in larval fat body. [Date last reviewed: 2018-09-13]
FBgn0013272	Gp150	Gp150	Gp150 (Gp150) encodes a transmembrane glycoprotein that regulates Notch signaling and is involved in eye development. [Date last reviewed: 2019-03-07]
FBgn0013303	Nca	Neurocalcin	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0013305	Nmda1	N-methyl-D-aspartate receptor-associated protein	NA
FBgn0013325	RpL11	Ribosomal protein L11	NA
FBgn0013334	Sap47	Synapse-associated protein 47kD	Synapse-associated protein 47kD (Sap47) encodes a conserved protein associated with synaptic vesicles. It is required for intact synaptic and behavioural plasticity. [Date last reviewed: 2019-03-14]
FBgn0013343	Syx1A	Syntaxin 1A	NA
FBgn0013347	TfIIA-S	Transcription-factor-IIA-S	Transcription-factor-IIA-S (TfIIA-S) encodes one of the basal transcription factors required for the formation of the pre-initiation complex (PIC) at Pol II-transcribed genes. It stabilizes the product of Tbp-TATA box interaction, thus promoting PIC formation. [Date last reviewed: 2019-03-14]
FBgn0013432	bcn92	bcn92	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0013435	Cdc2rk	Cdc2-related kinase	Cdc2-related kinase (Cdc2rk) encodes a kinase that might be involved in cell cycle regulation. [Date last reviewed: 2019-08-01]
FBgn0013531	MED20	Mediator complex subunit 20	NA
FBgn0013548	l(2)dtl	lethal-(2)-denticleless	lethal-(2)-denticleless (l(2)dtl) encodes the Cdt2 protein, which functions as a substrate receptor for a Cul4-based E3 ubiquitin ligase. The ubiquitylation and subsequent destruction of Cdt2 substrates depends on DNA synthesis that occurs during S phase or after DNA damage and includes proteins involved in genome function and maintenance. [Date last reviewed: 2019-09-26]
FBgn0013563	Pex1	Peroxin 1	Peroxin 1 (Pex1) encodes a member of the family of AAA-ATPases required for peroxisome assembly. Pex1 loss results in disorganization of neurons and glia and embryonic lethality. Larval escapers exhibit developmental delay, poor feeding and uncoordinated locomotion. [Date last reviewed: 2019-03-14]
FBgn0013576	mtd	mustard	mustard (mtd) encodes an ecdysone-regulated late puff protein. A isoform including only the C-terminal with a TLDc domain enters the nucleus. This isoform increases intestinal stem cell division and suppresses expression of the antimicrobial peptide encoded by DptA at the transcriptional level, independent of IMD pathway signaling. [Date last reviewed: 2019-03-14]
FBgn0013672	mt:ATPase6	mitochondrial ATPase subunit 6	mitochondrial ATPase subunit 6 (mt:ATPase6) encodes a mitochondrial inner transmembrane protein that is key for oxidative phosphorylation. It couples hydrogen ion transport to ATP synthesis functioning as part of the ATP synthase. [Date last reviewed: 2019-03-14]
FBgn0013674	mt:CoI	mitochondrial Cytochrome c oxidase subunit I	mitochondrial Cytochrome c oxidase subunit I (mt:CoI) is a mitochondrial gene encoding one of the catalytic subunits of the mitochondrial electron transport chain complex IV, which reduces molecular oxygen to water. [Date last reviewed: 2019-03-14]
FBgn0013675	mt:CoII	mitochondrial Cytochrome c oxidase subunit II	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0013676	mt:CoIII	mitochondrial Cytochrome c oxidase subunit III	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0013678	mt:Cyt-b	mitochondrial Cytochrome b	NA
FBgn0013679	mt:ND1	mitochondrial NADH-ubiquinone oxidoreductase chain 1	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0013684	mt:ND5	mitochondrial NADH-ubiquinone oxidoreductase chain 5	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0013686	mt:lrRNA	mitochondrial large ribosomal RNA	NA
FBgn0013717	not	non-stop	non-stop (not) encodes a component of the Spt-Ada-Gcn5 Acetyltransferase (SAGA) chromatin modifying complex. It deubiquitinates the product of His2B at active promoters, thereby promoting transcription elongation. It was first identified for its role in neural development in the optic lobe. [Date last reviewed: 2019-03-14]
FBgn0013718	nuf	nuclear fallout	nuclear fallout (nuf) encodes a cytoplasmic, coiled-coil protein that acts as an adaptor between the product of Rab11 and motor proteins in the recycling endosome pathway. It is required for early embryo cellularization, and for subsequent Rab11-dependent processes. [Date last reviewed: 2019-03-14]
FBgn0013720	pck	pickel	pickel (pck) encodes a transmembrane protein of the Claudin superfamily. It is part of the septate junction (SJ) core complex and essential for SJ morphogenesis and function. The transepithelial barrier function of epithelial tissues is affected in pck mutants. [Date last reviewed: 2019-03-14]
FBgn0013726	pnut	peanut	peanut (pnut) encodes a protein that belongs to the septin family of polymerizing GTPases. Together with the products of Septin1 and Septin2, it forms the septin complex. It participates in cytokinesis and other processes that involve organization of the cell cortex. [Date last reviewed: 2019-03-14]
FBgn0013732	sced	scrambled	scrambled (sced) encodes a protein that localizes to the mitotic furrows and centrosomes. It is involved in actin reorganization during cell cycle and the assembly of pseudocleavage furrows in syncytial embryos. [Date last reviewed: 2019-09-19]
FBgn0013733	shot	short stop	short stop (shot) encodes a member of the spectraplakin family of large cytoskeletal linker molecules. It binds both actin and microtubules, as well as scaffold proteins, certain signalling factors and calcium. It plays developmental and maintenance roles in the nervous system, the epidermis, at muscle attachments, the foregut, the wing, tracheae and oocytes. [Date last reviewed: 2019-03-14]
FBgn0013746	alien	alien	alien (alien) encodes the subunit 2 of the COP9 signalosome, which plays a central role in the regulation of E3-cullin RING ubiquitin ligases. [Date last reviewed: 2019-03-07]
FBgn0013749	Arf102F	ADP ribosylation factor at 102F	NA
FBgn0013750	Arf51F	ADP ribosylation factor at 51F	ADP ribosylation factor at 51F (Arf51F) belongs to the Arf family, which are members of the Ras superfamily of small GTPases. Arf proteins are involved in the regulation of vesicular trafficking mediating processes such as cargo-sorting, vesicle assembly and membrane fusion. Arf proteins regulate cell shape changes and cell movements in multiple organs. [Date last reviewed: 2019-03-07]
FBgn0013753	Bgb	Big brother	Big brother (Bgb) encodes a beta-subunit of the transcription factor complex core binding factor, which is involved in transcription regulation. It regulates hemocyte proliferation and acts redundantly with the product of Bro in embryonic segmentation. [Date last reviewed: 2019-03-07]
FBgn0013756	Mtor	Megator	Megator (Mtor) encodes a nuclear pore protein that is found in the nuclear matrix surrounding the chromosomes at interphase. During mitosis Mtor product dynamically reorganizes, together with other nuclear and cytoplasmic proteins (such as those encoded by Skeletor, Chro, east, and Asator), to form a gel-like spindle matrix embedding the microtubule spindle apparatus. Mtor product is important for normal cell cycle progression, functioning as a spatial regulator of cell cycle factors. [Date last reviewed: 2018-09-13]
FBgn0013759	CASK	CASK	CASK (CASK) encodes a member of the MAGUK family of scaffolding proteins. In epithelial tissues, the product of CASK functions as an adhesion molecule involved in cell proliferation, cytoskeletal remodeling and cell migration. In neurons, the product of CASK serves as a scaffold for a number of signaling and transmembrane molecules and is involved in synaptic development and plasticity. [Date last reviewed: 2019-03-07]
FBgn0013762	Cdk5	Cyclin-dependent kinase 5	Cyclin-dependent kinase 5 (Cdk5) encodes a protein serine-threonine kinase of the cyclin-dependent kinase family whose activity is largely restricted to post-mitotic neurons. It is required for synaptic homeostasis and fidelity of axon patterning, and altered activity causes adult-onset neurodegeneration. [Date last reviewed: 2019-03-07]
FBgn0013763	Idgf6	Imaginal disc growth factor 6	Imaginal disc growth factor 6 (Idgf6) is one of six genes in the IDGF family, which evolved from chitinases that lost their enzymatic activity. Idgf6 encodes a secreted protein that is highly expressed in larval fat body and adult head. Idgf6 product is involved in molting and egg chamber tube morphogenesis. [Date last reviewed: 2018-09-13]
FBgn0013764	Chi	Chip	Chip (Chi) encodes a transcriptional co-factor that regulates gene expression. It contributes to the regulation of Notch signaling, leg development and axon guidance. [Date last reviewed: 2019-09-12]
FBgn0013765	cnn	centrosomin	centrosomin (cnn) encodes an essential mitotic centrosome component. During early embryogenesis it is required to organize the mitotic spindle, the actin cytoskeleton and centriole replication. It is also required for mitotic and meiotic divisions during spermatogenesis, as well as organization of the sperm axoneme. The product of cnn can interact with microtubules, actin and the kinase encoded by polo. [Date last reviewed: 2019-05-23]
FBgn0013770	Cp1	Cysteine proteinase-1	NA
FBgn0013771	Cyp6a9	Cytochrome P450 6a9	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0013773	Cyp6a22	Cytochrome P450 6a22	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0013799	Deaf1	Deformed epidermal autoregulatory factor-1	NA
FBgn0013810	Dhc36C	Dynein heavy chain at 36C	Dynein heavy chain at 36C (Dhc36C) encodes a motor protein involved in hearing. [Date last reviewed: 2019-08-01]
FBgn0013811	Dhc62B	Dynein heavy chain at 62B	Dynein heavy chain at 62B (Dhc62B) encodes a motor protein involved in retrograde axonal transport. [Date last reviewed: 2019-08-01]
FBgn0013953	Esp	Epidermal stripes and patches	Epidermal stripes and patches (Esp) encodes a protein involved in female remating receptivity. [Date last reviewed: 2019-09-12]
FBgn0013954	Fkbp12	FK506-binding protein 12kD	FK506-binding protein 12kD (Fkbp12) encodes a protein that binds the intracellular calcium channel encoded by RyR in an oxidation dependent manner. Loss of the binding between the products of Fkbp12 and RyR results in increased calcium leak and reduced muscle function. [Date last reviewed: 2019-03-21]
FBgn0013981	His4r	Histone H4 replacement	NA
FBgn0013983	imd	immune deficiency	immune deficiency (imd) encodes a canonic component of the immune deficiency pathway, which regulates the antibacterial response and other less characterized cellular processes. [Date last reviewed: 2019-03-07]
FBgn0013987	MAPk-Ak2	MAP kinase activated protein-kinase-2	NA
FBgn0013997	Nrx-IV	Neurexin IV	Neurexin IV (Nrx-IV) encodes a transmembrane protein that is critical for septate junction formation in epithelia and between ensheathing glial cells and neurons. [Date last reviewed: 2019-03-14]
FBgn0014006	Ask1	Apoptotic signal-regulating kinase 1	Apoptotic signal-regulating kinase 1 (Ask1) encodes a serine/threonine kinase that belongs to the MAPK kinase kinase family. In response to various stresses, it phosphorylates MAPK kinases in JNK and p38 MAPK pathways, inducing cellular stress responses including cell death and immune responses. [Date last reviewed: 2019-03-07]
FBgn0014007	Ptp69D	Protein tyrosine phosphatase 69D	Protein tyrosine phosphatase 69D (Ptp69D) encodes a transmembrane receptor tyrosine phosphatase (RPTP). It genetically interacts with the other RPTP genes and its mutants have embryonic motor axon guidance phenotypes. In particular, Ptp10D-Ptp69D double mutants have a strong phenotype in which embryonic CNS axons abnormally cross the ventral midline. The product of Ptp69D physically and genetically interacts with the product of Dscam1 to regulate arborization of mechanosensory neurons. [Date last reviewed: 2019-03-14]
FBgn0014009	Rab2	Rab2	Rab2 (Rab2) encodes a protein that belongs to the Rab family of small Ras-like GTPases that regulate vesicle trafficking. Rab2 product contributes to the maturation and fusion of endosomes and autophagosomes with lysosomes. [Date last reviewed: 2018-09-13]
FBgn0014010	Rab5	Rab5	Rab5 (Rab5) encodes a monomeric GTPase that controls entry of endocytosed cargo into the early endosome and is required for vesicle re-uptake at the synapse. Altering the activity of the product of Rab5 affects many receptor-mediated signaling pathways as well as epithelial polarity. [Date last reviewed: 2019-03-14]
FBgn0014011	Rac2	Rac2	NA
FBgn0014018	Rel	Relish	Relish (Rel) encodes a transcription factor and the downstream component of the immune deficiency pathway, which regulates the antibacterial response and other less characterized cellular processes. [Date last reviewed: 2019-03-14]
FBgn0014020	Rho1	Rho1	Rho1 (Rho1) encodes a GTPase signaling protein that acts as a molecular switch and functions as key regulator of the actin cytoskeleton. It plays a central role in diverse biological processes including actin cytoskeleton organization, microtubule dynamics, mophogenesis, border cell migration, cytokinesis, and wound repair. [Date last reviewed: 2019-03-14]
FBgn0014022	Rlb1	Rlb1	NA
FBgn0014023	mRpL47	mitochondrial ribosomal protein L47	NA
FBgn0014024	Rnp4F	RNA-binding protein 4F	RNA-binding protein 4F (Rnp4F) encodes an essential evolutionarily-conserved RNA-binding protein. Rnp4F gene expression is post-transcriptionally regulated by interaction with a stable stem-loop structure in the 5'-UTR of the mRNA with trans-acting factors. [Date last reviewed: 2018-09-13]
FBgn0014026	RpL7A	Ribosomal protein L7A	Ribosomal protein L7A (RpL7A) encodes a ribosomal structural constituent. [Date last reviewed: 2019-07-11]
FBgn0014028	SdhB	Succinate dehydrogenase, subunit B (iron-sulfur)	Succinate dehydrogenase, subunit B (iron-sulfur) (SdhB) encodes the iron-sulfur cluster-containing subunit of the succinate dehydrogenase complex, which oxidizes succinate to fumarate and passes the electrons to quinones. The redox-active cofactors in this subunit are part of the electron transfer machinery in the complex. [Date last reviewed: 2019-09-26]
FBgn0014029	Septin2	Septin 2	NA
FBgn0014032	Sptr	Sepiapterin reductase	Sepiapterin reductase (Sptr) encodes a sepiapterin reductase involved in the biosynthesis of tetrahydrobiopterin. [Date last reviewed: 2019-09-19]
FBgn0014033	Sr-CI	Scavenger receptor class C, type I	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0014037	Su(Tpl)	Suppressor of Triplolethal	Su(Tpl) (Su(Tpl)) encodes a transcription elongation factor that enhances the catalytic rate of RNA Polymerase II by suppressing its transient pausing. It interacts with the product of lilli in the super elongation complex and the product of Ice1 in the little elongation complex. It regulates Notch and Ras signaling pathways. [Date last reviewed: 2019-09-26]
FBgn0014075	Uggt	UDP-glucose-glycoprotein glucosyltransferase	UDP-glucose-glycoprotein glucosyltransferase (Uggt) encodes an enzyme that recognizes glycoproteins with folding defects and adds glucose to N-glycans near the misfolded part of the protein. Uggt product is a component of the calnexin cycle and promotes protein folding in the endoplasmic reticulum along with the protein encoded by Cnx99A and Calr. [Date last reviewed: 2018-09-13]
FBgn0014092	CG4278	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0014127	barr	barren	barren (barr) encodes a chromatin binding protein involved in chromatin condensation. It regulates Malpighian tubule development and epithelial morphogenesis. [Date last reviewed: 2019-07-11]
FBgn0014133	bif	bifocal	bifocal (bif) encodes an actin and microtubule binding protein involved in axon guidance and regulation of axon extension. [Date last reviewed: 2019-09-19]
FBgn0014135	bnl	branchless	branchless (bnl) encodes a fibroblast growth factor (FGF) ligand for the transmembrane tyrosine kinase receptor encoded by btl that utilizes the intracellular Ras-MAP kinase pathway. It contributes to embryonic tracheal migration. [Date last reviewed: 2021-03-11]
FBgn0014141	cher	cheerio	cheerio (cher) encodes a dimeric F-actin crosslinking protein of the filamin protein family. It functions to organize the F-actin cytoskeleton in multiple contexts including ovarian germline ring canals, migrating somatic cells, and neuronal growth cones. [Date last reviewed: 2019-03-07]
FBgn0014163	fax	failed axon connections	NA
FBgn0014184	Oda	Ornithine decarboxylase antizyme	NA
FBgn0014189	Hel25E	Helicase at 25E	Helicase at 25E (Hel25E) encodes the UAP56 RNA helicase in the DECD subfamily of DEAD-box helicases. It is an enhancer of position-effect variegation, and contributes to mRNA splicing, nuclear export, and piRNA biosynthesis. The product of Hel25E binds heterochromatic cluster transcripts, along with the product of vas, to organize a piRNA-processing compartment that spans the nuclear envelope to silence transposon transcripts. [Date last reviewed: 2019-03-07]
FBgn0014269	prod	proliferation disrupter	NA
FBgn0014340	mof	males absent on the first	males absent on the first (mof) encodes a MYST family histone acetyltransferase that acetylates the product of His4 at Lysine 16. It is part of the male-specific lethal complex that mediates dosage compensation by transcriptional upregulation of the male X chromosome. In addition, it is part of the non-specific lethal complex which regulates expression of housekeeping genes in males and females. [Date last reviewed: 2019-03-14]
FBgn0014342	mia	meiosis I arrest	meiosis I arrest (mia) encodes a paralog of the generally expressed TBP-associated factor encoded by Taf6. mia is expressed only in differentiating male germ cells, starting in the spermatocyte stage. Along with four other testis-specific TBP-associated factors, the product of mia is required for full levels of transcript production from multiple genes expressed in primary spermatocytes in preparation for meiotic cell cycle progression and spermatid differentiation. [Date last reviewed: 2018-09-13]
FBgn0014366	noi	noisette	NA
FBgn0014380	RhoL	Rho-like	NA
FBgn0014388	sty	sprouty	NA
FBgn0014391	sun	stunted	NA
FBgn0014411	Vps26	Vacuolar protein sorting 26	NA
FBgn0014417	CG13397	NA	NA
FBgn0014427	CG11899	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0014455	Ahcy	Adenosylhomocysteinase	Adenosylhomocysteinase (Ahcy) encodes S-adenosyl-L-homocysteine hydrolase, the rate-limiting enzyme in methionine metabolism. This tetrameric enzyme catalyzes the reversible hydrolysis of S-Adenosylhomocysteine (SAH) to adenosine and L-homocysteine. The function of Ahcy product is required to maintain proper concentrations of SAH, which serves as an inhibitor of S-adenosylmethionine-dependent methylation reactions. [Date last reviewed: 2018-09-13]
FBgn0014469	Cyp4e2	Cytochrome P450 4e2	NA
FBgn0014857	His3.3A	Histone H3.3A	NA
FBgn0014861	Mcm2	Minichromosome maintenance 2	NA
FBgn0014868	Ost48	Oligosaccharyltransferase 48kD subunit	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0014869	Pglym78	Phosphoglyceromutase 78	Phosphoglyceromutase 78 (Pglym78) encodes an enzyme involved in myoblast fusion and somatic muscle development. [Date last reviewed: 2019-09-12]
FBgn0014870	Psi	P-element somatic inhibitor	P-element somatic inhibitor (Psi) encodes a protein that has dual roles in RNA processing and transcriptional regulation. It is required for activating Myc transcription. [Date last reviewed: 2019-03-14]
FBgn0014877	Roe1	Roe1	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0014879	Set	Set	Set (Set) encodes a subunit of the inhibitor of histone acetyltransferase (INHAT) complex, which controls histone acetylation. It is involved in transcriptional regulation, which ultimately controls different processes such as p53-mediated apoptosis and neuronal development. [Date last reviewed: 2019-03-14]
FBgn0014903	CG14630	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0014906	Hydr2	alpha/beta hydrolase2	α/β hydrolase2 (Hydr2) encodes a lipase involved in lipid metabolism. [Date last reviewed: 2019-09-19]
FBgn0014930	CG2846	NA	NA
FBgn0014931	CG2678	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0015000	betaggt-I	beta subunit of type I geranylgeranyl transferase	β subunit of type I geranylgeranyl transferase (βggt-I) encodes a protein involved in embryonic heart tube development. [Date last reviewed: 2019-09-19]
FBgn0015019	CCT3	Chaperonin containing TCP1 subunit 3	NA
FBgn0015024	CkIalpha	Casein kinase Ialpha	Casein kinase Iα (CkIα) encodes a member of the CK1 family of Ser/Thr kinases with a preference for acidic substrates. It is involved in multiple signaling pathways, including Wingless and Hedgehog, that control cell growth and patterning. [Date last reviewed: 2019-03-07]
FBgn0015025	CkIIalpha-i1	CKII-alpha subunit interactor-1	NA
FBgn0015031	cype	cyclope	cyclope (cype) encodes a cytochrome c oxidase subunit VIc homolog acting as an enhancer of dpp pathway phenotypes. It is involved in hair and cell growth and in ommatidia development. [Date last reviewed: 2019-03-07]
FBgn0015036	Cyp4ae1	Cytochrome P450 4ae1	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0015037	Cyp4p1	Cytochrome P450 4p1	NA
FBgn0015075	Ddx1	Dead-box-1	Dead-box-1 (Ddx1) encodes a member of the DEAD box family of RNA helicases that bind and unwind double-stranded RNA. Ddx1 product depletion is associated with small size and aberrant gametogenesis, possibly through alternative splicing of Sirup RNA transcript. [Date last reviewed: 2018-09-13]
FBgn0015218	eIF4E1	eukaryotic translation initiation factor 4E1	eukaryotic translation initiation factor 4E1 (eIF4E1) encodes a component of the eIF4F cap-binding complex that is essential for cap-dependent translation of mRNA. The product of eIF4E1 binds the 7-methyl-guanosine cap structure of mRNA. [Date last reviewed: 2019-03-07]
FBgn0015221	Fer2LCH	Ferritin 2 light chain homologue	Ferritin 2 light chain homologue (Fer2LCH) encodes one of two subunits of the major iron storage complex, the ferritin molecule. In insects, ferritin is assembled from 12 Fer1HCH and 12 Fer2LCH subunits and can be found in the secretory pathway of cells and in hemolymph. The product of Fer2LCH provides iron nucleation sites in the internal cavity of the complex required for iron mineralization and is essential for embryogenesis. [Date last reviewed: 2019-03-07]
FBgn0015222	Fer1HCH	Ferritin 1 heavy chain homologue	Ferritin 1 heavy chain homologue (Fer1HCH) encodes one of two subunits of the major iron storage complex, the ferritin molecule. In insects, ferritin is assembled from 12 Fer1HCH and 12 Fer2LCH subunits and can be found in the secretory pathway of cells and in hemolymph. The product of Fer1HCH has ferroxidase activity required for iron loading into ferritin and is essential for embryogenesis. [Date last reviewed: 2019-03-07]
FBgn0015229	glec	gliolectin	gliolectin (glec) encodes a member of carbohydrate-binding proteins. glec product regulates glia-glia and glia-neuron interactions during neurogenesis and positively regulates Notch pathway during the specification of vein and intervein regions in wing imaginal discs. [Date last reviewed: 2018-09-13]
FBgn0015239	Hr78	Hormone-receptor-like in 78	Hormone-receptor-like in 78 (Hr78) encodes a protein induced above a basal level by 20-hydroxyecdysone. Hr78 mutants die during mid-larval stages with defects in molting of the tracheal cuticle. [Date last reviewed: 2019-03-07]
FBgn0015240	Hr96	Hormone receptor-like in 96	Hormone receptor-like in 96 (Hr96) encodes a protein that binds cholesterol as a ligand and is required to maintain cholesterol and lipid homeostasis. [Date last reviewed: 2019-03-07]
FBgn0015245	Hsp60A	Heat shock protein 60A	NA
FBgn0015247	Diap2	Death-associated inhibitor of apoptosis 2	Death-associated inhibitor of apoptosis 2 (Diap2) encodes a protein with ubiquitin E3-ligase activity that functions in the Imd pathway by conjugating the product of imd with K63-polyubiquitin chains. [Date last reviewed: 2019-03-07]
FBgn0015268	Nap1	Nucleosome assembly protein 1	Nucleosome assembly protein 1 (Nap1) encodes a core histone chaperone involved in histone nuclear transfer and chromatin assembly. [Date last reviewed: 2019-03-14]
FBgn0015269	Nf1	Neurofibromin 1	Neurofibromin 1 (Nf1) encodes a protein that functions as a GTPase activating protein for the products of Ras85D and Ras64B in the larval and adult nervous system. Loss of Nf1 results in excess Ras-Raf-ERK signaling and to a non-cell-autonomous cAMP/PKA signaling defect. The product of Nf1 contributes to postembryonic growth, learning/memory, and circadian rhythm. [Date last reviewed: 2019-03-14]
FBgn0015270	Orc2	Origin recognition complex subunit 2	Origin recognition complex subunit 2 (Orc2) encodes a subunit of the origin recognition complex (ORC), which is essential for the initiation of DNA replication in eukaryotic cells. The product of Orc2 can be phosphorylated by CK2 and Cdks in vivo and in vitro. [Date last reviewed: 2019-03-14]
FBgn0015271	Orc5	Origin recognition complex subunit 5	NA
FBgn0015277	Pi3K59F	Phosphatidylinositol 3-kinase 59F	Phosphotidylinositol 3 kinase 59F (Pi3K59F) encodes a lipid kinase that is required for formation of Phosphatidylinositol 3-phosphate. It functions in a core protein complex that includes the products of Atg6 and Vps15. It is involved in the control of vesicle trafficking, including autophagy, endocytosis and phagocytosis. [Date last reviewed: 2019-03-14]
FBgn0015278	Pi3K68D	Phosphatidylinositol 3-kinase 68D	Phosphotidylinositol 3 kinase 68D (Pi3K68D) encodes a phosphatidylinositol kinase involved in the organization of the cortical actin cytoskeleton and the regulation of the Egfr signaling pathway. [Date last reviewed: 2019-09-19]
FBgn0015279	Pi3K92E	Phosphatidylinositol 3-kinase 92E	Pi3K92E (Pi3K92E) encodes the catalytic subunit of a class I phosphatidylinositol 3-kinase that functions downstream of the product of InR and other receptors during several processes, including cell and tissue growth. [Date last reviewed: 2018-09-13]
FBgn0015282	Rpt2	Regulatory particle triple-A ATPase 2	Regulatory particle triple-A ATPase 2 (Rpt2) encodes one of six ATPases that form the base of the regulatory 19S cap of the proteasome. The Rpt2 product is involved in the recognition of specific substrates destined for degradation, such as those involved in Notch signalling pathway. [Date last reviewed: 2018-09-20]
FBgn0015283	Rpn10	Regulatory particle non-ATPase 10	Regulatory particle non-ATPase 10 (Rpn10) encodes one of the polyubiquitin receptor subunits of the 26S proteasome. It recognizes and binds the polyubiquitin moiety of proteins intended for proteasomal degradation or the ubiquitin-like domain of extraproteasomal ubiquitin receptors. [Date last reviewed: 2019-03-14]
FBgn0015286	Rala	Ras-like protein A	Ras-like protein A (Rala) encodes a GTPase that regulates Notch, Jak/Stat and JNK signalling pathways. [Date last reviewed: 2019-08-01]
FBgn0015288	RpL22	Ribosomal protein L22	Ribosomal protein L22 (RpL22) encodes a member of the eukaryotic ribosomal protein eL22 family. It is ubiquitously expressed, forms part of the large ribosomal subunit and is involved in protein synthesis. [Date last reviewed: 2018-09-20]
FBgn0015295	Shark	SH2 ankyrin repeat kinase	SH2 ankyrin repeat kinase (Shark) encodes a non-receptor tyrosine kinase of the Syk family. It contributes to embryonic dorsal closure, chorion formation and engulfment of dying neurons. [Date last reviewed: 2019-03-14]
FBgn0015296	Shc	SHC-adaptor protein	SHC-adaptor protein (Shc) encodes a protein involved in receptor tyrosine kinase signalling. It regulates anti-parasitoid immune response and tracheal development. [Date last reviewed: 2019-03-14]
FBgn0015298	Srp19	Signal recognition particle 19	NA
FBgn0015299	Ssb-c31a	Single stranded-binding protein c31A	NA
FBgn0015320	Ubc2	Ubiquitin conjugating enzyme 2	NA
FBgn0015321	Ubc4	Ubiquitin conjugating enzyme 4	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0015331	abs	abstrakt	abstrakt (abs) encodes a protein that belongs to the DEAD/DEAH box helicase family. It is involved in the post-transcriptional regulation of insc levels and affects cell polarity, asymmetric cell divisions, axon outgrowth and fasciculation. [Date last reviewed: 2019-03-07]
FBgn0015338	CG5861	NA	CG5861 encodes a transmembrane protein involved in phagocytosis. [Date last reviewed: 2019-03-07]
FBgn0015359	CG2034	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0015360	oxt	peptide O-xylosyltransferase	peptide O-xylosyltransferase (oxt) encodes an enzyme that catalyzes the first xylose of the linkage region of glycosaminoglycan (GAG). Through GAG synthesis, the product of oxt is involved in several signaling pathways mediated by GAGs in development. [Date last reviewed: 2019-03-14]
FBgn0015371	chn	charlatan	charlatan (chn) encodes a C2H2 zinc-finger transcriptional factor that regulates multiple genes, including emc, h, ac and Dl. It functions in sensory neurons, photoreceptors, blood cells, muscle precursors and intestinal precursors. [Date last reviewed: 2018-09-20]
FBgn0015372	RabX1	RabX1	Rab10 (Rab10) encodes a small GTPase that contributes to vesicle trafficking regulation. It is involved in basement membrane organization. [Date last reviewed: 2019-09-26]
FBgn0015376	cutlet	cutlet	NA
FBgn0015379	dod	dodo	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0015391	glu	gluon	gluon (glu) encodes a subunit of the multiprotein complex condensin that is required for chromosome condensation and sister chromatid segregation. It contributes to nervous system development and glucose metabolism. [Date last reviewed: 2019-03-07]
FBgn0015396	jumu	jumeau	jumeau (jumu) encodes a multi-functional transcription factor that acts upstream of a Polo-kinase dependent pathway in one report. Its roles include asymmetric protein localization, chromatin modification, dendrite formation and organ (eye, wing and bristle) development. [Date last reviewed: 2019-03-07]
FBgn0015399	kek1	kekkon 1	kekkon 1 (kek1) encodes a transmembrane protein that acts in a negative feedback loop to modulate the activity of the product of Egfr in a number of tissues, including follicle cells and imaginal discs. It also plays a role in axonal outgrowth in the central nervous system. [Date last reviewed: 2019-03-14]
FBgn0015402	ksr	kinase suppressor of ras	kinase suppressor of ras (ksr) encodes a MAP-kinase scaffold protein. It mediates the activation of the serine/threonine kinase encoded by Dsor1. [Date last reviewed: 2019-06-13]
FBgn0015477	Rme-8	Receptor mediated endocytosis 8	Receptor mediated endocytosis 8 (Rme-8) encodes a protein involved in the regulation of border follicle cell migration and the endocytosis of the receptor encoded by N. [Date last reviewed: 2019-08-01]
FBgn0015509	Cul1	Cullin 1	NA
FBgn0015513	mbc	myoblast city	myoblast city (mbc) encodes an unconventional bipartite GEF that, in combination with the product of Ced-12, activates the monomeric GTPase encoded by Rac1. It contributes to myoblast fusion, border cell migration and dorsal closure. [Date last reviewed: 2019-03-14]
FBgn0015520	nonA-l	nonA-like	NA
FBgn0015521	RpS21	Ribosomal protein S21	NA
FBgn0015522	olf186-M	olf186-M	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0015527	peng	penguin	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0015544	spag	spaghetti	spaghetti (spag) encodes a TPR domain-containing co-chaperone that associates with Hsp70 and Hsp90 to regulate their activity in macromolecular complexes like RNA polymerase, ribonucleoproteins and Phosphatidyl-Inositol 3-kinase-related kinases. It has been shown to regulate the product of dco levels, with consequences for circadian rhythms and apoptosis. [Date last reviewed: 2019-03-14]
FBgn0015546	spel1	spellchecker1	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0015553	tos	tosca	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0015558	tty	tweety	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0015568	alpha-Est1	alpha-Esterase-1	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0015569	alpha-Est10	alpha-Esterase-10	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0015571	alpha-Est3	alpha-Esterase-3	NA
FBgn0015575	alpha-Est7	alpha-Esterase-7	α-Esterase-7 (α-Est7) encodes a carboxylic ester hydrolase involved in insecticide tolerance, lipid metabolism and lifespan control. [Date last reviewed: 2019-09-19]
FBgn0015576	alpha-Est8	alpha-Esterase-8	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0015577	alpha-Est9	alpha-Esterase-9	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0015582	dare	defective in the avoidance of repellents	defective in the avoidance of repellents (dare) encodes an enzyme associated with steroid hormone synthesis and required for normal olfactory behavior. Some mutants show widespread degeneration of adult nervous system. [Date last reviewed: 2019-03-07]
FBgn0015589	Apc	APC-like	APC-like (Apc) encodes one of two Drosophila APC family proteins. It is a key negative regulator of Wingless signaling, as a critical component of the destruction complex that phosphorylates beta-catenin and thus targets it for ubiquitination and proteasomal destruction. It is the primary family member during CNS and eye development, and functions redundantly with the product of Apc2 in adult development. [Date last reviewed: 2019-03-07]
FBgn0015600	toc	toucan	toucan (toc) encodes a protein that associates with spindle microtubules being involved in mitotic spindle organization, mitotic sister chromatid segregation and ovarian follicle cell formation. [Date last reviewed: 2019-03-14]
FBgn0015602	BEAF-32	Boundary element-associated factor of 32kD	Boundary element-associated factor of 32kD (BEAF-32) encodes a DNA-binding protein with binding sites near transcription start sites. Its roles include chromatin domain insulator function, gene regulation and genome organization. [Date last reviewed: 2019-03-07]
FBgn0015614	CanB2	Calcineurin B2	NA
FBgn0015615	SMC3	Structural maintenance of chromosomes 3	Structural maintenance of chromosomes 3 (SMC3) encodes a subunit of the cohesin complex. It is involved in planar cell polarity by regulating the membrane enrichment of the transmembrane cadherin encoded by stan. [Date last reviewed: 2019-07-11]
FBgn0015618	Cdk8	Cyclin-dependent kinase 8	NA
FBgn0015621	Clp	Clipper	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0015622	Cnx99A	Calnexin 99A	Calnexin 99A (Cnx99A) encodes an endoplasmic reticulum chaperone that colocalizes and genetically interacts with the sodium channel subunit encoded by para. [Date last reviewed: 2018-09-20]
FBgn0015623	Cpr	Cytochrome P450 reductase	NA
FBgn0015625	CycB3	Cyclin B3	Cyclin B3 (CycB3) encodes a protein that binds to the product of Cdk1, presumably promoting Cdk1's protein kinase activity. The complex CycB3-Cdk1 cooperates with other Cdk1 complexes (CycA-Cdk1 and CycB-Cdk1) to promote the G2/M transition. Like the products of CycA and CycB, the product of CycB3 is also rapidly degraded during exit from mitosis and during G1. It appears to have a specific role in activating the APC/C-dependent degradation pathway. [Date last reviewed: 2019-03-21]
FBgn0015663	Ugt36A1	UDP-glycosyltransferase family 36 member A1	UDP-glycosyltransferase family 36 member A1 (Ugt36A1) encodes a member of the superfamily of UDP glycosyltransferase enzymes, which are found across all kingdoms and are involved in detoxification of endogenous and xenobiotic compounds. [Date last reviewed: 2019-03-14]
FBgn0015664	Dref	DNA replication-related element factor	DNA replication-related element factor (Dref) encodes a BED finger-type transcription factor that binds to the DRE sequence (TATCGATA). The Dref product is involved in tumor suppressor, TOR, JNK and EGFR signalling pathways. It also plays a role in chromatin organization including insulator function, chromatin remodeling, and telomere maintenance. [Date last reviewed: 2018-09-20]
FBgn0015714	Cyp6a17	Cytochrome P450 6a17	Cytochrome P450-6a17 (Cyp6a17) encodes a member of the cytochrome P450 (CYP) family of proteins involved in the oxidation of diverse organic substrates. Cyp6a17 expression in the mushroom bodies of the brain is regulated by cAMP-dependent protein kinase (PKA) and is required for temperature preference behavior. [Date last reviewed: 2019-03-07]
FBgn0015737	Hmu	Hemomucin	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0015754	Lis-1	Lissencephaly-1	Lissencephaly-1 (Lis-1) encodes a regulator of the cytoplasmic dynein-1 motor complex, binding to Dynein heavy chain and regulating dynein force production, microtubule affinity and velocity. It is involved in the transport of many of dynein's cargoes, including mRNPs, mitochondria and nuclei. The Lis-1 product is also a non-catalytic subunit of platelet-activating factor acetylhydrolase. [Date last reviewed: 2018-09-20]
FBgn0015756	RpL9	Ribosomal protein L9	Ribosomal protein L9 (RpL9) encodes a ribosomal structural constituent. [Date last reviewed: 2019-07-11]
FBgn0015765	p38a	p38a MAP kinase	p38a MAP kinase (p38a) encodes a member of the mitogen-activated protein kinases responsive to diverse stresses. In immune response, it activates its downstream component encoded by Atf-2 that in turn regulates Duox expression. [Date last reviewed: 2019-03-14]
FBgn0015772	Nak	Numb-associated kinase	Numb-associated kinase (Nak) encodes an Ark family member that regulates the product of numb function. It contributes to dendrite development by regulating clathrin localization. [Date last reviewed: 2019-03-14]
FBgn0015774	NetB	Netrin-B	NA
FBgn0015776	nrv1	nervana 1	nervana 1 (nrv1) encodes a β subunit of the Na[+], K[+] ATPase ion pump, which is important for maintaining cellular membrane potential in muscles. [Date last reviewed: 2019-03-14]
FBgn0015777	nrv2	nervana 2	NA
FBgn0015778	rin	rasputin	rasputin (rin) encodes an RNA-binding protein that regulates gene expression. It is involved in eye development and the dorsal/ventral axis specification of the ovary. [Date last reviewed: 2019-09-26]
FBgn0015781	P5cr	Pyrroline 5-carboyxlate reductase	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0015789	Rab10	Rab10	Rab10 (Rab10) encodes a small GTPase that contributes to vesicle trafficking regulation. It is involved in basement membrane organization. [Date last reviewed: 2019-09-26]
FBgn0015790	Rab11	Rab11	Rab11 (Rab11) encodes a Rab type protein. Rab proteins are ubiquitously expressed family of small monomeric Ras-like GTPases that are key regulators of endomembrane traffiking, regulating exocytosis, endocytosis and membrane recycling processes essential for maintaining various cellular functions. [Date last reviewed: 2019-03-14]
FBgn0015791	Rab14	Rab14	Rab14 (Rab14) encodes a protein involved in phagocytosis, phagolysosome assembly and phagosome maturation. [Date last reviewed: 2019-08-01]
FBgn0015793	Rab19	Rab19	NA
FBgn0015794	Rab18	Rab18	NA
FBgn0015795	Rab7	Rab7	Rab7 (Rab7) encodes a small GTPase that contributes to vesicle trafficking regulation. It is involved in endosome maturation and fusion with lysosomes. [Date last reviewed: 2019-09-26]
FBgn0015797	Rab6	Rab6	Rab6 (Rab6) encodes a member of the Rab family, which are small Ras-like GTPases involved in vesicle trafficking. The Rab6 product localizes on late Golgi, and regulates vesicle trafficking within Golgi, post-Golgi, and endosome to Golgi. [Date last reviewed: 2018-09-20]
FBgn0015799	Rbf	Retinoblastoma-family protein	Retinoblastoma-family protein (Rbf) encodes a protein that binds to members of the E2F transcription factors and forms the DREAM complex, which regulates genes with diverse biological functions including cell cycle regulators, apoptosis regulators, and DNA replication/repair factors. The product of Rbf can also bind chromosomal proteins and modulate genome stability. It is negatively regulated by CycE-Cdk2 and CycD-Cdk4 cyclin-dependent kinase complexes. [Date last reviewed: 2019-03-14]
FBgn0015801	Reg-5	Rhythmically expressed gene 5	NA
FBgn0015803	RtGEF	Rho-type guanine nucleotide exchange factor	Rho-type guanine nucleotide exchange factor (RtGEF) encodes a putative Rho-type guanine nucleotide exchange factor for the GTPases encoded by Rac1 and Cdc42. It signals through the sterile-20 kinases encoded by Pak and hpo. The product of RtGEF contributes to regulation of postsynaptic structure, post synaptic muscle development, protein localization and the growth of epithelial tissue. [Date last reviewed: 2019-03-14]
FBgn0015805	HDAC1	Histone deacetylase 1	NA
FBgn0015808	ScpX	Sterol carrier protein X-related thiolase	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0015818	Spx	Spliceosomal protein on the X	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0015828	TfIIEalpha	Transcription factor IIEalpha	Transcription factor IIEα (TfIIEα) encodes the large subunit of the RNA polymerase II general transcription factor TFIIE. The products of TfIIEα and TfIIEβ are essential for transcription initiation in vitro acting with RNA polymerase II and the other general transcription factors. [Date last reviewed: 2019-03-14]
FBgn0015829	TfIIEbeta	Transcription factor IIEbeta	NA
FBgn0015834	eIF3i	eukaryotic translation initiation factor 3 subunit i	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0015838	Vang	Van Gogh	Van Gogh (Vang) encodes a four-pass transmembrane protein that localizes to cell junctions. It is part of the Frizzled-dependent planar polarity pathway that establishes planar polarity in epithelia. It is also implicated in nervous system patterning. [Date last reviewed: 2019-03-21]
FBgn0015903	apt	apontic	apontic (apt) encodes a DNA-binding protein that acts as a transcriptional regulator and can function in translational repression. It plays roles in cell migration, cell fate specification, and morphogenesis via STAT signaling pathway inhibition. [Date last reviewed: 2019-03-07]
FBgn0015905	ast	asteroid	asteroid (ast) encodes an interactor protein of the product of Egfr that is involved in photoreceptor and wing development. [Date last reviewed: 2019-03-07]
FBgn0015924	crq	croquemort	croquemort (crq) encodes a member of the scavenger receptor class B sub-family. It is expressed in plasmatocyte/macrophages and promotes apoptotic cell clearance. In epidermal cells it plays a role in phagosome maturation in both dendrite pruning and injury. [Date last reviewed: 2019-03-07]
FBgn0015925	csul	capsuleen	capsuleen (csul) encodes a protein arginine methyltransferase that carries out symmetric dimethylation of arginine residues. It forms a complex with the product of vls, which is the substrate recognition subunit. Primary substrates for this complex include the spliceosomal Sm proteins. The products of csull and vls function in germline specification and are required for proper localization of the product of tud to the posterior pole of the oocyte. [Date last reviewed: 2019-03-07]
FBgn0015926	dah	discontinuous actin hexagon	discontinuous actin hexagon (dah) encodes a protein required for cortical furrows during early embryogenesis that is recruited to the membrane in a process dependent on the product of nuf. [Date last reviewed: 2019-03-07]
FBgn0015929	dpa	disc proliferation abnormal	NA
FBgn0015949	hrg	hiiragi	hiiragi (hrg) encodes the canonical poly(A) polymerase required for the nuclear poly(A) tail synthesis at the mRNA 3'-end. hrg product is also involved in cytoplasmic polyadenylation of specific mRNAs during early to mid-oogenesis, through its interaction with the CPEB (cytoplasmic polyadenylation element binding) protein encoded by orb. [Date last reviewed: 2018-09-20]
FBgn0016031	lama	lamina ancestor	NA
FBgn0016032	lbm	late bloomer	NA
FBgn0016034	mael	maelstrom	NA
FBgn0016038	Vsp37A	Vacuolar protein sorting 37A	NA
FBgn0016041	Tom40	Translocase of outer membrane 40	Translocase of outer membrane 40 (Tom40) encodes a protein predicted to be a channel component of the TOM complex, which is involved in protein import into mitochondria. It is predicted to be involved in the cellular response to hypoxia. [Date last reviewed: 2019-03-14]
FBgn0016054	phr6-4	(6-4)-photolyase	(6-4)-photolyase (phr6-4) encodes an enzyme that repairs DNA damage induced by ultraviolet light. It uses blue light and cofactor FADH to reverse the pyrimidine(6-4)pyrimidone photoproduct. [Date last reviewed: 2019-09-26]
FBgn0016059	Sema1b	Semaphorin 1b	NA
FBgn0016070	smg	smaug	smaug (smg) encodes the founding member of the SMAUG family of sequence-specific RNA-binding proteins. During the maternal-to-zygotic transition in early embryos, the smg product inhibits the translation and induces the degradation of hundreds of maternal mRNAs by recruitment of the CCR4-NOT deadenylase complex, thereby controlling embryonic patterning, activation of zygotic transcription, and early embryonic cell cycles. [Date last reviewed: 2018-09-20]
FBgn0016075	vkg	viking	viking (vkg) encodes a subunit of Collagen IV and a major component of basement membranes. It is secreted by haemocytes and fat body cells and is required for the normal morphogenesis of many tissues. It also contributes to TGF-beta signalling in the early embryo and the developing Malpighian tubules. [Date last reviewed: 2019-03-21]
FBgn0016076	vri	vrille	vrille (vri) encodes a bZIP transcription factor acting as an enhancer of dpp phenotypes both in embryo and in wing. It is involved in hair and cell growth and in tracheal development. Vri is a clock-controlled gene acting as a repressor of the products of Clk and cry. [Date last reviewed: 2019-03-21]
FBgn0016078	wun	wunen	wunen (wun) encodes a lipid phosphate phosphatase with 6 transmembrane domains and an active site that is predicted to face extracellularly. It is required for germ cell migration and survival, septate junction function in the tracheal system and for heart formation. [Date last reviewed: 2019-03-21]
FBgn0016081	fry	furry	furry (fry) encodes a large conserved protein that functions with the product of trc. Its mutations lead to mulitpled hairs, split and multipled arista laterals and to defects in dendritic tiling. [Date last reviewed: 2019-03-07]
FBgn0016119	ATPsynCF6	ATP synthase, coupling factor 6	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0016120	ATPsynD	ATP synthase, subunit D	NA
FBgn0016122	Acer	Angiotensin-converting enzyme-related	Angiotensin-converting enzyme-related (Acer) encodes an enzyme with peptidyl-dipeptidase activity that regulates heart rate and circadian sleep/wake cycle. [Date last reviewed: 2019-03-07]
FBgn0016123	Alp4	Alkaline phosphatase 4	NA
FBgn0016126	CaMKI	Calcium/calmodulin-dependent protein kinase I	NA
FBgn0016131	Cdk4	Cyclin-dependent kinase 4	Cyclin-dependent kinase 4 (Cdk4) encodes a protein that contributes to cell cycle progression and cell growth. It is involved in the regulation of JAK-STAT and TORC1 signalling pathways. [Date last reviewed: 2019-09-12]
FBgn0016641	PTP-ER	Protein tyrosine phosphatase-ERK/Enhancer of Ras1	Protein tyrosine phosphatase-ERK/Enhancer of Ras1 (PTP-ER) encodes a phosphatase required for mitosis. It is involved in RAS/MAPK signaling regulation and eye development. [Date last reviewed: 2019-08-01]
FBgn0016672	Ipp	Inositol polyphosphate 1-phosphatase	Inositol polyphosphate 1-phosphatase (Ipp) encodes a protein involved in synaptic transmission and inositol metabolism regulation. [Date last reviewed: 2019-08-01]
FBgn0016685	Nlp	Nucleoplasmin	NA
FBgn0016687	Nurf-38	Nucleosome remodeling factor - 38kD	NA
FBgn0016691	ATPsynO	ATP synthase, oligomycin sensitivity conferring protein	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0016693	Past1	Putative Achaete Scute Target 1	Putative Achaete Scute Target 1 (Past1) encodes a protein that associates predominantly with the plasma membrane and genetically interacts with N. It contributes to endocytosis, male sterility, temperature sensitivity, life span and differentiation of photoreceptors R1/R6/R7 and cone cells. [Date last reviewed: 2019-03-14]
FBgn0016694	Pdp1	PAR-domain protein 1	PAR-domain protein 1 (Pdp1) encodes a member of the PAR domain bZip family of sequence-specific transcription factors. it regulates gene expression in muscles and in circadian clock neurons. [Date last reviewed: 2019-03-14]
FBgn0016696	Pitslre	Pitslre	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0016697	Prosalpha5	Proteasome alpha5 subunit	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0016698	Ptpa	Phosphotyrosyl phosphatase activator	Phosphotyrosyl phosphatase activator (Ptpa) encodes a nuclear protein that associates with the catalytic subunit of the PP4 complex encoded by Pp4-19C in larval brain neuroblasts. It facilitates the dephosphorylation and basal distribution of the mira protein during neuroblast asymmetric division. [Date last reviewed: 2018-09-20]
FBgn0016701	Rab4	Rab4	Rab4 (Rab4) encodes a member of the Rab family, which are small Ras-like GTPases involved in vesicle trafficking. The product of Rab4 controls endocytic recycling and regulates synapse organization and neurotransmission in the nervous system. It also contributes to the sorting of cell adhesion molecules during epithelial morphogenesis and immune-mediators during the innate immune response. [Date last reviewed: 2018-09-20]
FBgn0016715	Reg-2	Rhythmically expressed gene 2	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0016726	RpL29	Ribosomal protein L29	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0016754	sba	six-banded	NA
FBgn0016756	Usp47	Ubiquitin specific protease 47	NA
FBgn0016762	angel	angel	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0016794	dos	daughter of sevenless	NA
FBgn0016797	fz2	frizzled 2	NA
FBgn0016917	Stat92E	Signal-transducer and activator of transcription protein at 92E	Signal-transducer and activator of transcription protein at 92E (Stat92E) encodes a transcription factor that shuttles between the cytosol and nucleus and functions in the JAK/STAT pathway. Its roles include proliferation, growth control, organismal metabolism, cell competition, stem cell self-renewal, immunity and developmental patterning. [Date last reviewed: 2019-03-14]
FBgn0016919	nompB	no mechanoreceptor potential B	no mechanoreceptor potential B (nompB) encodes an essential component of the conserved intraflagellar transport mechanism, which is needed to extend cilia above the cell surface. nompB mutants have truncated, nonfunctional sensory cilia with consequent mechanosensory deficits. [Date last reviewed: 2019-03-14]
FBgn0016926	Pino	Pinocchio	NA
FBgn0016930	Dyrk2	Dual-specificity tyrosine phosphorylation-regulated kinase 2	NA
FBgn0016970	l(2)k10201	lethal (2) k10201	NA
FBgn0016977	spen	split ends	NA
FBgn0016978	snRNP-U1-70K	small ribonucleoprotein particle U1 subunit 70K	small ribonucleoprotein particle U1 subunit 70K (snRNP-U1-70K) encodes a protein component of the U1 snRNP. The U1 snRNP combines with other snRNPs on the pre-mRNA to assemble a spliceosome. [Date last reviewed: 2019-03-14]
FBgn0016983	smid	smallminded	NA
FBgn0016984	sktl	skittles	skittles (sktl) encodes the major Phosphatidylinositol 4-Phosphate-5 kinase (PI4P5K), catalysing the formation of phosphoinositol-4,5-bisphosphate (PIP4,5). The sktl product is involved in many cellular processes involving (PIP4,5), such as endocytosis. It plays an important role in cell polarity by controlling the localization of the product encoded by baz. [Date last reviewed: 2018-09-20]
FBgn0017414	cag	cag	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0017418	ari-1	ariadne 1	ariadne 1 (ari-1) encodes an E3 ubiquitin ligase that interacts with the E2 ubiquitin conjugating enzyme encoded by Ubc10. The product of ari-1 and Ubc10 jointly ubiquitylate isoform A of the ecdysone receptor encoded by EcR. [Date last reviewed: 2019-03-07]
FBgn0017429	CG5989	NA	NA
FBgn0017430	Nelf-E	Negative elongation factor E	Negative elongation factor E (Nelf-E) encodes one of four subunits that constitutes the NELF complex, which along with the product of spt4 causes the promoter proximal pause of the RNA polymerase II. [Date last reviewed: 2019-03-14]
FBgn0017457	U2af38	U2 small nuclear riboprotein auxiliary factor 38	U2 small nuclear riboprotein auxiliary factor 38 (U2af38) encodes the small subunit of the pre-mRNA splicing factor complex U2AF. This heterodimeric complex binds to the intron pyrimidine tract and targets the product of snf to the branch site early in spliceosome assembly. The U2af38 product binds to the AG dinucleotide at the 3' splice site. [Date last reviewed: 2018-09-20]
FBgn0017482	T3dh	Type III alcohol dehydrogenase	NA
FBgn0017545	RpS3A	Ribosomal protein S3A	Ribosomal protein S3A (RpS3A) encodes an essential component of the small ribosomal subunit that functions in protein synthesis. It is classified as a 'Minute' gene as heterozygous mutants exhibit a slower developmental rate and small adult bristles. [Date last reviewed: 2019-03-14]
FBgn0017550	Rga	Regena	NA
FBgn0017551	Rca1	Regulator of cyclin A1	Regulator of cyclin A1 (Rca1) encodes an anaphase-promoting complex/cyclosome inhibitor. It contributes to mitotic G1/S transition and cyclin degradation. [Date last reviewed: 2019-07-11]
FBgn0017558	Pdk	Pyruvate dehydrogenase kinase	NA
FBgn0017566	ND-75	NADH dehydrogenase (ubiquinone) 75 kDa subunit	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0017567	ND-23	NADH dehydrogenase (ubiquinone) 23 kDa subunit	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0017572	Mo25	Mo25	Mo25 (Mo25) encodes a protein involved in neuroblast asymmetric cell divisions via localization of the product of mira. It physically interacts with the kinase encoded by Lkb1. [Date last reviewed: 2019-03-14]
FBgn0017577	Mcm5	Minichromosome maintenance 5	Minichromosome maintenance 5 (Mcm5) encodes a protein that is involved in mitotic DNA replication and is required to resolve meiotic double-strand breaks into crossovers. [Date last reviewed: 2018-09-20]
FBgn0017578	Max	Max	Max (Max) encodes a member of the basic-helix-loop-helix-zipper family of transcription factors. It specifically forms heterodimers with the products of Myc and Mnt enabling the binding and transcriptional activity of the heterodimeric complex, which regulate genes involved in cell and organismal growth. [Date last reviewed: 2019-03-14]
FBgn0017579	RpL14	Ribosomal protein L14	Ribosomal protein L14 (RpL14) encodes a component of the large subunit of cytoplasmic ribosomes, which translate mRNAs encoded by the nuclear genome. RpL14 is haploinsufficient - heterozygous mutants display the 'Minute' phenotype, characterized by a slower developmental rate and small adult bristles. [Date last reviewed: 2019-03-14]
FBgn0017581	Lk6	Lk6 kinase	Lk6 kinase (Lk6) encodes the single ortholog of MAPK signal integrating kinases, which are phosphorylated and activated by ERK. Lk6 product phosphorylates the protein encoded by eIF4E1 to influence translation initiation via formation of the eIF4F complex. [Date last reviewed: 2018-09-20]
FBgn0019624	COX5A	Cytochrome c oxidase subunit 5A	NA
FBgn0019637	Atu	Another transcription unit	NA
FBgn0019644	ATPsynB	ATP synthase, subunit B	ATP synthase, subunit B (ATPsynB) encodes a protein proposed to act in ATP synthesis and phagocytosis. Ubiquitous knockdown of ATPsynB results in larval growth defects, while knockdown in testes causes male infertility. [Date last reviewed: 2018-09-20]
FBgn0019660	lncRNA:roX2	long non-coding RNA on the X 2	NA
FBgn0019661	lncRNA:roX1	long non-coding RNA on the X 1	NA
FBgn0019662	qm	quemao	quemao (qm) encodes the ortholog of human geranylgeranyl pyrophosphate synthase (GGPS1), which catalyses protein prenylation and thereby facilitates membrane targeting of proteins. The qm product contributes to heart formation, germ cell migration, and maintenance of plasma membrane integrity in growing oocytes. [Date last reviewed: 2018-09-20]
FBgn0019686	lok	loki	NA
FBgn0019830	colt	congested-like trachea	NA
FBgn0019890	Smg5	Smg5 nonsense mediated mRNA decay factor	Smg5 (Smg5) encodes a protein involved in mRNA catabolism. [Date last reviewed: 2019-09-19]
FBgn0019925	Surf4	Surfeit 4	NA
FBgn0019932	SamDC	S-adenosylmethionine decarboxylase	S-adenosylmethionine decarboxylase (SamDC) encodes a protein involved in defense response to Gram-negative bacterium. [Date last reviewed: 2019-07-11]
FBgn0019936	RpS20	Ribosomal protein S20	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0019938	Polr1A	RNA polymerase I subunit A	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0019949	Cdk9	Cyclin-dependent kinase 9	Cyclin-dependent kinase 9 (Cdk9) encodes a cyclin dependent kinase that along with the product of CycT forms the positive transcription elongation factor, which is involved in RNA polymerase II elongation control. [Date last reviewed: 2019-03-07]
FBgn0019952	Orct	Organic cation transporter	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0019957	ND-42	NADH dehydrogenase (ubiquinone) 42 kDa subunit	NADH dehydrogenase (ubiquinone) 42 kDa subunit (ND-42) encodes an ortholog of human NDUFA10, a subunit of complex I of the mitochondrial electron transport chain (NADH:ubiquinone reductase). ND-42 acts genetically as a suppressor of some Pink1 phenotypes. [Date last reviewed: 2019-09-26]
FBgn0019960	Mitofilin	Mitofilin	Mitofilin (Mitofilin) encodes a major component of the mitochondrial contact site (MICOS) complex, which is located at the mitochondrial crista junctions. It maintains crista structure and contact sites, and regulates mitochondrial motility. Mitofilin product functions downstream of the kinase encoded by Pink1, to maintain mitochondrial structure and cellular homeostasis. [Date last reviewed: 2018-10-04]
FBgn0019968	Khc-73	Kinesin heavy chain 73	Kinesin heavy chain 73 (Khc-73) encodes a member of the Kinesin-3 family of microtubule-based transport motors. It facilitates endosomal transport during interphase and modulates cortical polarity during asymmetric neuroblast cell division. [Date last reviewed: 2018-10-04]
FBgn0019972	Drice	Death related ICE-like caspase	Death related ICE-like caspase (Drice) encodes a major effector apoptotic caspase. It is essential for both developmental and damaged induced cell death, as well as several non-apoptotic vital cellular processes. It is activated by the product of Dark and the initiator caspase encoded by Dronc and is inhibited by the inhibitor of apoptosis encoded by Diap1. [Date last reviewed: 2019-03-07]
FBgn0019982	Gs1l	GS1-like	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0019985	mGluR	metabotropic Glutamate Receptor	NA
FBgn0019990	Gcn2	Gcn2	Gcn2 (Gcn2) encodes a kinase activated during amino acid starvation to phosphorylate the eIF2 subunit encoded by eIF2α. Gcn2 product plays roles in ageing, dpp signalling, dietary choice and response to infection. [Date last reviewed: 2018-10-04]
FBgn0020018	Ppox	Protoporphyrinogen oxidase	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0020224	Cbl	Cbl proto-oncogene	Cbl proto-oncogene (Cbl) encodes an E3 protein-ubiquitin ligase for protein post-translational modification in RTK signaling (EGFR, VEGFR, FGF, and RET families) and non-RTK signaling (Src family). After the ubiquitination mediated by the product of Cbl, the substrates will be targeted to protein degradation for controlling cell growth, survival, migration and inflammation. [Date last reviewed: 2019-03-07]
FBgn0020235	ATPsyngamma	ATP synthase, gamma subunit	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0020236	ATPCL	ATP citrate lyase	ATP citrate lyase (ATPCL) encodes a protein involved in glucose homeostasis. [Date last reviewed: 2019-09-12]
FBgn0020238	14-3-3epsilon	14-3-3epsilon	14-3-3ε (14-3-3ε) encodes an acidic protein that preferentially heterodimerizes with other members of the family but also can homodimerize. It functions in multiple signaling pathways, most prominently in the Ras/MAPK cascade. It is involved in embryonic hatching, germ cell migration, gonad formation, wing venation and eye development. [Date last reviewed: 2019-03-07]
FBgn0020249	stck	steamer duck	steamer duck (stck) encodes PINCH, an adapter protein that directly binds and forms a complex with the products of Ilk and ics. PINCH is required for integrin-dependent cell adhesion and signaling. [Date last reviewed: 2019-03-14]
FBgn0020251	sfl	sulfateless	NA
FBgn0020255	Ran	Ran	NA
FBgn0020257	Ppa	Partner of paired	Partner of paired (Ppa) encodes a protein involved in response to oxidative stress. [Date last reviewed: 2019-03-14]
FBgn0020261	pcm	pacman	pacman (pcm) encodes an exoribonuclease that degrades decapped mRNA. It is involved in epithelial closure, male fertility, apoptosis and growth control. [Date last reviewed: 2019-09-26]
FBgn0020270	mre11	meiotic recombination 11	meiotic recombination 11 (mre11) encodes a protein involved in the mitotic G2 DNA damage checkpoint and telomere capping. [Date last reviewed: 2019-09-26]
FBgn0020272	mst	misato	misato (mst) encodes a conserved protein that acts as a co-factor of the TCP-1 tubulin chaperone complex. It is required for mitotic spindle assembly and viability and for tubulin polymerization and stability. [Date last reviewed: 2019-03-14]
FBgn0020278	loco	locomotion defects	locomotion defects (loco) encodes a regulator of G-protein signalling protein. loco product functions in neuroblast asymmetric division and blood-brain barrier formation together with G protein-coupled receptors and inhibitory G-proteins (encoded by Gαi and Gαo). It is also known that decrease of loco expression extends lifespan with stronger resistance to stressors. [Date last reviewed: 2018-10-04]
FBgn0020279	lig	lingerer	lingerer (lig) encodes a putative RNA binding protein that forms a complex with the products of orb and orb2. Loss of lig results in defects in copulation and short-term memory. [Date last reviewed: 2019-03-14]
FBgn0020304	drongo	drongo	NA
FBgn0020305	dbe	dribble	NA
FBgn0020306	dom	domino	domino (dom) encodes a protein of the SWI2/SNF2 class of DNA-dependent ATPases. It is a component of the Tip60 acetyltransferase complex and functions in the exchange of histone His2Av. dom product contributes to Notch signaling and cell death regulation, as well as numerous other processes. [Date last reviewed: 2018-10-04]
FBgn0020309	crol	crooked legs	crooked legs (crol) encodes a zinc finger transcription factor induced by 20-hydroxyecdysone at the onset of metamorphosis. It regulates wg transcription and cell cycle progression in the wing. Its over-expression in the eye accelerates the cell cycle and de-represses silenced genes. [Date last reviewed: 2019-03-07]
FBgn0020312	Tmtc3	Transmembrane O-mannosyltransferase targeting cadherins 3	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0020369	Rpt6	Regulatory particle triple-A ATPase 6	Regulatory particle triple-A ATPase 6 (Rpt6) encodes a subunit of the proteasome, which is responsible for the ATP-dependent degradation of obsolete or damaged proteins. Rpt6 product belongs to the heterohexameric ring formed by triple-A ATPases that unfolds ubiquitinated target proteins before their degradation. [Date last reviewed: 2018-10-04]
FBgn0020370	TppII	Tripeptidyl-peptidase II	tripeptidyl-peptidase II (TppII) encodes an exopeptidase that removes tripeptides from the free N-terminus of longer peptides. [Date last reviewed: 2018-10-04]
FBgn0020372	TM4SF	Transmembrane 4 superfamily	NA
FBgn0020376	Sr-CIII	Scavenger receptor class C, type III	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0020379	Rfx	Rfx	Rfx (Rfx) encodes a transcription factor involved in the differentiation of ciliated sensory neurons. [Date last reviewed: 2019-09-12]
FBgn0020381	Dredd	Death related ced-3/Nedd2-like caspase	Death related ced-3/Nedd2-like caspase (Dredd) encodes a protein that functions downstream of Fadd, and is thought to activate by cleavage the transcription factor encoded by Rel in the immune deficiency pathway. This pathway regulates the antibacterial response and other less characterized cellular processes. [Date last reviewed: 2019-03-07]
FBgn0020385	pug	pugilist	pugilist (pug) encodes the trifunctional enzyme methylenetetrahydrofolate dehydrogenase involved in the pigmentation of pteridines and ommochromes. [Date last reviewed: 2019-09-12]
FBgn0020386	Pdk1	Phosphoinositide-dependent kinase 1	NA
FBgn0020388	Gcn5	Gcn5 acetyltransferase	Gcn5 acetyltransferase (Gcn5) encodes a lysine acetyltransferase subunit of several chromatin modifying complexes. It contributes to oogenesis and metamorphosis. [Date last reviewed: 2019-08-01]
FBgn0020389	Papss	PAPS synthetase	PAPS synthetase (Papss) encodes an enzyme that catalyzes the synthesis of 3'-phosphoadenosine 5'-phosphosulfate (PAPS), the sulfate donor compound in all sulfotransferase reactions. Maternally provided Papss product is required for the formation of the embryonic dorsal-ventral axis mediated by the sulfotransferase encoded by pip. [Date last reviewed: 2018-10-04]
FBgn0020391	Nrk	Neurospecific receptor kinase	Neurospecific receptor kinase (Nrk) encodes a receptor tyrosine kinase that is expressed in the developing nervous system and regulates axon pathfinding and rhabdomere elongation. It interacts genetically with Dys and Dg. [Date last reviewed: 2019-03-14]
FBgn0020392	Nmt	N-myristoyl transferase	NA
FBgn0020407	asun	asunder	NA
FBgn0020412	JIL-1	JIL-1 kinase	JIL-1 kinase (JIL-1) encodes a Serine/Threonine tandem kinase that phosphorylates the Serine 10 residue of the product of His3. A key function of the product of JIL-1 is to antagonize heterochromatization and to regulate levels of gene expression by controlling the distribution of the Lysine 9 dimethylation mark of the epigenetic histone encoded by His3. [Date last reviewed: 2019-03-07]
FBgn0020414	Idgf3	Imaginal disc growth factor 3	Imaginal disc growth factor 3 (Idgf3) encodes a member of the chitinase-like protein family that was originally shown to facilitate insulin signalling in imaginal disc cell lines. Idgf3 product is a component of hemolymph clot, aids in wound healing and protects against certain infections. [Date last reviewed: 2018-10-04]
FBgn0020415	Idgf2	Imaginal disc growth factor 2	Imaginal disc growth factor 2 (Idgf2) encodes a secreted glycoprotein that is a member of the chitinase-like protein family mainly expressed in fat body and hemocytes. Idgf2 product is induced under stress conditions. [Date last reviewed: 2018-10-04]
FBgn0020416	Idgf1	Imaginal disc growth factor 1	Imaginal disc growth factor 1 (Idgf1) encodes a member of the chitinase-like protein family. Idgf1 is expressed in the ectodermally-derived cuticle forming organs and its product is required for the formation of the chitinous apical extracellular matrix during larval development. [Date last reviewed: 2018-10-04]
FBgn0020440	Fak	Focal adhesion kinase	Focal adhesion kinase (Fak) encodes a non-Receptor Tyrosine kinase (nRTK) that is involved in signaling and cytoskeletal dynamics integrating signals from RTKs and integrins. Its function has been described in multiple contexts including embryonic muscle attachement, morphogensis of the optic stalk, synaptic growth and transmission, and in the regulation of RTK-MAP kinase signaling in epithelia. [Date last reviewed: 2019-03-07]
FBgn0020443	eRF3	eukaryotic translation release factor 3	eukaryotic translation release factor 3 (eRF3) encodes a GTP-binding protein important in the termination of protein translation. [Date last reviewed: 2019-03-07]
FBgn0020493	Dad	Daughters against dpp	Daughters against dpp (Dad) encodes the inhibitory SMAD in the BMP/Dpp pathway. It is involved in growth regulation and developmental patterning. [Date last reviewed: 2018-10-04]
FBgn0020496	CtBP	C-terminal Binding Protein	NA
FBgn0020497	emb	embargoed	embargoed (emb) encodes an exportin involved in protein export from the nucleus. It regulates the response to hypoxia and is involved in centriole replication. [Date last reviewed: 2019-03-07]
FBgn0020503	CLIP-190	Cytoplasmic linker protein 190	NA
FBgn0020510	Abi	Abelson interacting protein	Abelson interacting protein (Abi) encodes a protein that interacts with the non-receptor tyrosine kinase encoded by Abl. It contributes to the regulation of actin cytoskeleton organization. It is involved in multiple actin dependent processes including cell adhesion, cell morphogenesis, oogenesis, muscle attachment and axogenesis. [Date last reviewed: 2019-09-26]
FBgn0020513	Paics	PAICS bifunctional enzyme	PAICS bifunctional enzyme (Paics) encodes an essential enzyme in the pathway for de novo synthesis of the purine nucleotide inosine monophosphate (IMP). IMP is the precursor for purine nucleotides required for nucleic acids, energy transfer, cell signaling, and coenzymes. [Date last reviewed: 2019-03-14]
FBgn0020545	kraken	kraken	NA
FBgn0020616	SA	Stromalin	Stromalin (SA) encodes a subunit of the cohesin ring complex, which encircles sister chromatids after DNA replication and has multiple roles in the regulation of gene expression and DNA repair. [Date last reviewed: 2019-03-14]
FBgn0020618	Rack1	Receptor of activated protein kinase C 1	Receptor of activated protein kinase C 1 (Rack1) encodes a cytosolic adaptor protein that is essential during development, particularly oogenesis. [Date last reviewed: 2019-03-14]
FBgn0020620	RN-tre	Related to the N terminus of tre oncogene	Related to the N terminus of tre oncogene (RN-tre) encodes a protein involved in border cell migration. [Date last reviewed: 2019-08-01]
FBgn0020621	Pkn	Protein kinase N	Protein kinase N (Pkn) encodes a serine/threonine protein kinase activated by Rho family GTPases, especially those encoded by Rho1 and Rac1. When activated, the product of Pkn regulates the actin cytoskeleton during oogenesis, wound repair, and in morphogenetic events including dorsal closure and wing development. [Date last reviewed: 2019-03-14]
FBgn0020622	Pi3K21B	Pi3K21B	Pi3K21B (Pi3K21B) encodes an adaptor protein (p60) that binds the product of Pi3K92E to form the functional cllass IA phosphoinositide 3-kinase. This heterodimeric kinase is involved in phosphatidylinositol phosphorylation and regulates cell size and proliferation. [Date last reviewed: 2019-09-12]
FBgn0020626	Osbp	Oxysterol binding protein	Oxysterol binding protein (Osbp) encodes a protein important for sperm development. [Date last reviewed: 2019-03-14]
FBgn0020633	Mcm7	Minichromosome maintenance 7	Minichromosome maintenance 7 (Mcm7) encodes a component of the MCM2-7 hexamer, which forms part of the CMG complex, together with CDC45L and GINS proteins. CMG complex is the main DNA helicase that functions during DNA replication. [Date last reviewed: 2018-10-04]
FBgn0020647	KrT95D	Krueppel target at 95D	NA
FBgn0020653	Trxr-1	Thioredoxin reductase-1	NA
FBgn0020655	ArfGAP1	ADP-ribosylation factor GTPase activating protein 1	NA
FBgn0020660	eIF4B	eukaryotic translation initiation factor 4B	eukaryotic translation initiation factor 4B (eIF4B) encodes a protein involved in cap-dependent translation, cell survival, and proliferation. [Date last reviewed: 2019-07-11]
FBgn0020762	Atet	ABC transporter expressed in trachea	ABC transporter expressed in trachea (Atet) encodes a protein that is involved in transmembrane transport. [Date last reviewed: 2019-08-01]
FBgn0020764	Alas	Aminolevulinate synthase	Aminolevulinate synthase (Alas) encodes a mitochondrial enzyme involved in cuticle barrier formation and thought to have a role in Heme biosynthesis. [Date last reviewed: 2019-03-07]
FBgn0020767	Spred	Sprouty-related protein with EVH-1 domain	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0020887	Su(z)12	Su(z)12	Su(z)12 (Su(z)12) is a member of the Polycomb group of genes with products involved in transcriptional silencing. Su(z)12 encodes a subunit of Polycomb repressive complex 2 (PRC2), where it is required for the histone methyltransferase activity that yields trimethylation of histone H3 on lysine 27 (H3-K27me3). [Date last reviewed: 2019-09-26]
FBgn0020909	Rtc1	Rtc1	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0020910	RpL3	Ribosomal protein L3	NA
FBgn0020930	Dgkepsilon	Diacyl glycerol kinase epsilon	Diacyl glycerol kinase ε (Dgkε) encodes a kinase that plays a key role in the metabolism of diacylglycerol by converting diacylglycerol into phosphatidic acid. [Date last reviewed: 2019-09-12]
FBgn0021750	SerRS-m	Seryl-tRNA synthetase, mitochondrial	Seryl-tRNA synthetase, mitochondrial (SerRS-m) encodes an enzyme that catalyses the aminoacylation of tRNAser with serine, to be used for gene translation during protein synthesis. [Date last reviewed: 2019-03-14]
FBgn0021760	chb	chromosome bows	chromosome bows (chb) encodes a microtubule plus-end tracking protein that promotes stabilization of microtubule dynamics. It is required for several mitotic aspects such as kinetochore attachment and central spindle formation. chb product is also essential for construction of polarized microtubule network in egg chambers and fusome formation in spermatogenesis and oogenesis. [Date last reviewed: 2018-10-04]
FBgn0021761	Nup154	Nucleoporin 154kD	NA
FBgn0021764	sdk	sidekick	NA
FBgn0021765	scu	scully	scully (scu) encodes a mitochondrial protein that is part of a three protein complex responsible for cleaving the 5'-end of mitochondrial tRNAs. scu product forms a sub-complex with the protein encoded by rswl. This sub-complex binds the tRNA and recruits the metallonuclease encoded by mldr, which is responsible for cleaving the phosphodiester backbone of the RNA. Loss of scu results in lethality and aberrantly processed mtDNA transcripts. [Date last reviewed: 2018-10-04]
FBgn0021768	nudC	nudC	nudC (nudC) encodes a component of a specialized dynein complex involved in nucleus localization and positive regulation of dendrite morphogenesis. [Date last reviewed: 2019-09-26]
FBgn0021795	Tapdelta	Translocon-associated protein delta	NA
FBgn0021796	Tor	Target of rapamycin	NA
FBgn0021800	Reph	Regulator of eph expression	Regulator of eph expression (Reph) encodes a putative nuclear protein involved in visual system development via the regulation of the product of Eph. [Date last reviewed: 2019-03-14]
FBgn0021814	Vps28	Vacuolar protein sorting 28	Vacuolar protein sorting 28 (Vps28) encodes a member of the ESCRT-I complex, which sorts certain endocytosed receptors for degradation via the multivesicular body. [Date last reviewed: 2019-03-21]
FBgn0021825	DCTN2-p50	Dynactin 2, p50 subunit	Dynactin 2, p50 subunit (DCTN2-p50) encodes a subunit of the dynactin complex. Together with other members of the dynactin complex, the product of DCTN2-p50 is critical for most functions of the minus end-directed microtubule motor cytoplasmic dynein-1, including oocyte polarity, mRNA localization, centrosome localizations, spindle organization, endocytosis and axonal transport. [Date last reviewed: 2018-10-04]
FBgn0021847	Ttc7	Tetratricopeptide repeat domain 7	NA
FBgn0021856	l(2)k14505	lethal (2) k14505	NA
FBgn0021872	Xbp1	X box binding protein-1	X box binding protein-1 (Xbp1) encodes a transcription factor that mediates the unfolded protein response. Xbp1 mRNA undergoes splicing after being cleaved by the product of Ire1, inducing the expression of ER quality control transcripts. Xbp1 mutants fail to develop beyond the 2nd instar larval stage, indicative of a requirement to resolve inherent ER stress during normal development. [Date last reviewed: 2019-03-21]
FBgn0021874	Nle	Notchless	NA
FBgn0021875	Zfrp8	Zinc finger protein RP-8	Zinc finger protein RP-8 (Zfrp8) encodes a highly conserved protein essential for stem cell maintenance and fast proliferating cells such as cancer cells. It functions in the formation of mRNA ribonucleoprotein (mRNP) complexes. It may regulate the binding of specific mRNPs to the small ribosomal subunit, ultimately controlling their cytoplasmic localization and translation. [Date last reviewed: 2019-03-21]
FBgn0021895	ytr	yantar	yantar (ytr) encodes a conserved arginine-rich protein involved in alternative splicing and hemocyte differentiation. [Date last reviewed: 2018-10-04]
FBgn0021906	RFeSP	Rieske iron-sulfur protein	NA
FBgn0021944	Coprox	Coproporphyrinogen oxidase	NA
FBgn0021967	ND-PDSW	NADH dehydrogenase (ubiquinone) PDSW subunit	NA
FBgn0021979	l(2)k09913	lethal (2) k09913	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0021995	Rs1	Rs1	NA
FBgn0022023	eIF3h	eukaryotic translation initiation factor 3 subunit h	NA
FBgn0022027	Vps25	Vacuolar protein sorting 25	Vacuolar protein sorting 25 (Vps25) encodes a member of the ESCRT-II complex, which sorts certain endocytosed receptors for degradation via the multivesicular body. As part of this complex, the product of Vps25 also has a role in bcd RNA localization. [Date last reviewed: 2019-03-21]
FBgn0022029	l(2)k01209	lethal (2) k01209	NA
FBgn0022069	Nnp-1	Nnp-1	NA
FBgn0022097	Vha36-1	Vacuolar H[+] ATPase 36kD subunit 1	NA
FBgn0022153	l(2)k05819	lethal (2) k05819	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0022160	Gpo1	Glycerophosphate oxidase 1	Glycerophosphate oxidase 1 (Gpo1) encodes a mitochondrial inner membrane protein with glycerol-3-phosphate dehydrogenase activity. [Date last reviewed: 2019-03-07]
FBgn0022213	Cse1	Chromosome segregation 1	NA
FBgn0022224	ubl	ubiquitin like	NA
FBgn0022238	lolal	lola like	lola like (lolal) encodes a small BTB-domain protein related to the Trithorax group of chromatin regulators. lolal transcripts are found in oocytes and the protein translocates to embryonic nuclei after the maternal to zygotic transition. lolal homozygous germline clone embryos show reduced dpp expression during dorsal-ventral patterning. [Date last reviewed: 2019-09-26]
FBgn0022288	l(2)09851	lethal (2) 09851	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0022338	dnk	deoxyribonucleoside kinase	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0022343	CG3760	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0022344	CG10340	NA	NA
FBgn0022349	CG1910	NA	NA
FBgn0022359	Sodh-2	Sorbitol dehydrogenase-2	NA
FBgn0022361	Pur-alpha	Purine-rich binding protein-alpha	Purine-rich binding protein-α (Pur-α) encodes a DNA- and RNA-binding protein involved in the regulation of transcription and cell-cycle. In the cytoplasm it is found in motile RNPs, indicating a role in RNA localization. [Date last reviewed: 2018-10-04]
FBgn0022382	Pka-R2	Protein kinase, cAMP-dependent, regulatory subunit type 2	NA
FBgn0022699	D19B	D19B	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0022702	Cht2	Chitinase 2	NA
FBgn0022709	Ak1	Adenylate kinase 1	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0022710	Ac13E	Adenylyl cyclase 13E	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0022724	Taf8	TBP-associated factor 8	NA
FBgn0022764	Sin3A	Sin3A	Sin3A (Sin3A) encodes a chromatin regulator with roles during muscle development, cell migration and Wnt signalling regulation. [Date last reviewed: 2019-09-12]
FBgn0022768	Pp2C1	Protein phosphatase 2C	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0022774	Oat	Ornithine aminotransferase precursor	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0022786	Hira	Hira	Hira (Hira) encodes a histone H3-H4 chaperone that specifically assembles nucleosomes containing the histone H3.3 variant. It is involved in various replication-independent nucleosome assembly processes and is critically required for de novo chromatin assembly in the male pronucleus. [Date last reviewed: 2019-03-14]
FBgn0022787	Hel89B	Helicase 89B	Helicase 89B (Hel89B) encodes a protein that belongs to the SNF2 family of chromatin regulators. Hel89B product binds to large number of sites on polytene chromosomes and positively regulates the expression of antimicrobial peptide genes. [Date last reviewed: 2018-10-04]
FBgn0022800	Cad96Ca	Cadherin 96Ca	Cadherin 96Ca (Cad96Ca) encodes a receptor tyrosine kinase (RTK) that is a direct target of the transcription factor encoded by grh and is required for epidermal wound healing. It cooperates with the product of InR during wing growth. [Date last reviewed: 2019-03-07]
FBgn0022893	Df31	Decondensation factor 31	Decondensation factor 31 (Df31) encodes a histone binding protein involved in nucleosome assembly. [Date last reviewed: 2019-09-12]
FBgn0022935	D19A	D19A	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0022936	CycH	Cyclin H	NA
FBgn0022942	Cbp80	cap binding protein 80	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0022943	Cbp20	cap binding protein 20	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0022959	yps	ypsilon schachtel	NA
FBgn0022960	vimar	visceral mesodermal armadillo-repeats	visceral mesodermal armadillo-repeats (vimar) encodes a protein involved in regulation of muscle homeostasis and rhabdomere development. Its expression in the visceral mesoderm is controlled by the product of bap. [Date last reviewed: 2019-03-21]
FBgn0022984	qkr58E-3	quaking related 58E-3	quaking related 58E-3 (qkr58E-3) encodes an RNA binding protein that contributes to mRNA splicing and apoptosis. [Date last reviewed: 2019-09-12]
FBgn0022985	qkr58E-2	quaking related 58E-2	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0022986	qkr58E-1	quaking related 58E-1	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0022987	qkr54B	quaking related 54B	NA
FBgn0023000	mth	methuselah	methuselah (mth) encodes a member of the Class B secretin family of G-protein-coupled receptors involved in lifespan. mth product also plays a role in the processes of learning and memory formation via the CREB pathway. [Date last reviewed: 2018-09-20]
FBgn0023023	CRMP	Collapsin Response Mediator Protein	Collapsin Response Mediator Protein (CRMP) encodes a protein that contributes to pyrimidine catabolism, beta-alanine biosynthesis, neurogenesis and behavior. [Date last reviewed: 2019-03-07]
FBgn0023081	gek	genghis khan	NA
FBgn0023083	fray	frayed	frayed (fray) encodes a serine/threonine-protein kinase required for axonal ensheathment. It is activated via phosphorylation by the kinase encoded by Wnk. The product of fray contributes to regulating ion transport, canonical Wnt signaling and asymmetric cell division. [Date last reviewed: 2019-06-13]
FBgn0023094	cyc	cycle	cycle (cyc) is a circadian clock gene. It encodes a transcription factor of the BHLH-PAS family and activates transcription of key clock genes as well as downstream clock-regulated genes. [Date last reviewed: 2018-09-20]
FBgn0023095	caps	capricious	capricious (caps) encodes a transmembrane receptor with leucine-rich repeats that mediates cell interaction in a homophilic or heterophilic manner. caps product contributes to cellular interaction critical for synapse formation and axon guidance, as well as mediating morphogenesis of multiple tissues, including wings, legs and the tracheal system. [Date last reviewed: 2018-09-20]
FBgn0023097	bon	bonus	bonus (bon) encodes a nuclear receptor cofactor involved in axon guidance and chromatin organization. [Date last reviewed: 2019-07-11]
FBgn0023129	aay	astray	NA
FBgn0023130	a6	a6	NA
FBgn0023143	Uba1	Ubiquitin activating enzyme 1	Ubiquitin activating enzyme 1 (Uba1) encodes an E1 enzyme involved in protein ubiquitylation. It contributes to multiple processes including regulation of Ras-ERK signaling, autophagy, apoptosis and tissue growth. [Date last reviewed: 2019-07-11]
FBgn0023167	SmD3	Small ribonucleoprotein particle protein SmD3	Small ribonucleoprotein particle protein SmD3 (SmD3) encodes an RNA binding protein that forms a heterodimeric sub-complex with the product of SmB. They function as part of the heteroheptameric ring complex Sm core, which is involved in the formation of spliceosomal small nuclear RNPs (U1, U2, U4 and U5), which together catalyze pre-mRNA splicing. The product of SmD3 also has a function in germline specification, as it is required for localization of the product of osk to the posterior pole of the oocyte. [Date last reviewed: 2019-03-14]
FBgn0023169	AMPKalpha	AMP-activated protein kinase alpha subunit	AMP-activated protein kinase α subunit (AMPKα) encodes the α subunit of the AMP-activated protein kinase (AMPK) complex. In general AMPK helps cells conserve energy through inhibition of energy consuming processes (fatty acid synthesis, protein synthesis). AMPK is usually active when the TOR pathway is inhibited. [Date last reviewed: 2019-03-07]
FBgn0023170	RpL39	Ribosomal protein L39	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0023171	rnh1	ribonuclease H1	ribonuclease H1 (rnh1) encodes a RNA-DNA hybrid ribonuclease. [Date last reviewed: 2019-09-12]
FBgn0023172	RhoGEF2	Rho guanine nucleotide exchange factor 2	Rho guanine nucleotide exchange factor 2 (RhoGEF2) encodes a protein involved in actin organization and contractility. It contributes to multiple actin-based processes including wound healing, cell shape and cell contraction. [Date last reviewed: 2019-08-01]
FBgn0023174	Prosbeta2	Proteasome beta2 subunit	Proteasome β2 subunit (Prosβ2) encodes a component of the 26S proteasome, which degrades polyubiquitinated proteins in the cytoplasm and nucleus. [Date last reviewed: 2019-08-01]
FBgn0023175	Prosalpha7	Proteasome alpha7 subunit	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0023177	Pp4-19C	Protein phosphatase 19C	NA
FBgn0023180	Orc6	Origin recognition complex subunit 6	Origin recognition complex subunit 6 (Orc6) encodes a subunit of the origin recognition complex (ORC), which is essential for the initiation of DNA replication in eukaryotic cells. Orc6 product has an additional independent function in cytokinesis through the interaction with the septin protein encoded by pnut. [Date last reviewed: 2019-03-21]
FBgn0023181	Orc4	Origin recognition complex subunit 4	Origin recognition complex subunit 4 (Orc4) encodes is a subunit of the hetero-hexameric origin recognition complex (ORC). The ORC binds to origins of DNA replication and scaffolds assembly of a pre-replicative complex, which is required for the initiation of DNA replication. At other loci, the ORC is required for heterochromatin formation. [Date last reviewed: 2019-03-14]
FBgn0023212	EloB	Elongin B	Elongin B (EloB) encodes an essential protein for development that participates in the control of wing cell identity. EloB, EloC and EloA encode for subunits of the Elongin complex, which interacts in vivo with the chromatin factor encoded by corto. The proteins encoded by EloB and EloC form an adaptor subcomplex of a Cul2-RING ubiquitin ligase complex. [Date last reviewed: 2019-03-07]
FBgn0023213	eIF4G1	eukaryotic translation initiation factor 4G1	eukaryotic translation initiation factor 4G1 (eIF4G1) encodes a protein that contributes to translation and spermatogenesis. [Date last reviewed: 2019-07-11]
FBgn0023214	edl	ETS-domain lacking	ETS-domain lacking (edl) encodes a protein involved in Egfr signaling pathway regulation. It regulates the transcriptional repressor encoded by aop. [Date last reviewed: 2019-03-07]
FBgn0023215	Mnt	Mnt	Mnt (Mnt) encodes a protein that belongs to the basic-helic-loop-helix-zipper class of transcription factors, which form heterodimers with the protein encoded by Max. Mnt product acts as a repressor of transcription by recruiting a co-repressor complex to its genomic binding sites. It antagonizes cell growth promoting functions of the product encoded by Myc and its depletion produces flies with larger cells, increased weight, and decreased lifespan. [Date last reviewed: 2018-09-20]
FBgn0023216	Parg	Poly(ADP-ribose) glycohydrolase	Poly(ADP-ribose) glycohydrolase (Parg) encodes a nuclear enzyme that degrades poly(ADP-ribose) to mono(ADP-ribose) from the acceptor proteins after their modification by the product of Parp. It performs several vital roles, including regulation of developmental patterning and germ-line stem cell fate. [Date last reviewed: 2019-09-26]
FBgn0023388	Dap160	Dynamin associated protein 160	Dynamin associated protein 160 (Dap160) encodes an adaptor protein that contributes to endocytosis. It regulates the Notch pathway and mediates the asymmetric accumulation of a number or proteins, including the product of aPKC during neuroblast division. [Date last reviewed: 2019-09-12]
FBgn0023395	Chd3	Chd3	Chd3 (Chd3) encodes a nuclear ATP-dependent nucleosome remodeler of the CHD family. It associates with active chromatin and utilizes the energy of ATP hydrolysis to move nucleosomes along DNA. [Date last reviewed: 2019-03-07]
FBgn0023407	B4	B4	B4 (B4) encodes a protein involved in imaginal disc development. [Date last reviewed: 2019-09-19]
FBgn0023416	Ac3	Adenylate cyclase 3	Adenylate cyclase 3 (Ac3) encodes an adenylate cyclase that is coupled to the receptor encoded by Pdfr via Gs signaling in the Morning circadian pacemakers. [Date last reviewed: 2019-03-07]
FBgn0023458	Rbcn-3A	Rabconnectin-3A	Rabconnectin-3A (Rbcn-3A) encodes a protein that is part of a regulatory subunit of the Vacuolar H[+] ATPase required for acidification of intracellular vesicles and the lysosome. It is involved in endocytic trafficking and lysosome function, and mutations block Notch signaling in follicle cells and imaginal disc cells. [Date last reviewed: 2019-03-14]
FBgn0023477	Taldo	Transaldolase	NA
FBgn0023479	teq	Tequila	NA
FBgn0023506	Es2	Es2	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0023507	D2hgdh	D-2-hydroxyglutaric acid dehydrogenase	D-2-hydroxyglutaric acid dehydrogenase (D2hgdh) encodes an enzyme involved in oxidation-reduction metabolism. [Date last reviewed: 2019-09-19]
FBgn0023508	Ocrl	Oculocerebrorenal syndrome of Lowe	Oculocerebrorenal syndrome of Lowe (Ocrl) encodes an inositol polyphosphate 5-phosphatase that regulates PtdIns(4,5)P2 homeostasis by dephosphorylating PtdIns(4,5)P2 on endocytic compartments. In vitro experiments also suggest a role of the product of Ocrl during cytokinesis. [Date last reviewed: 2019-03-14]
FBgn0023509	mip130	Myb-interacting protein 130	Myb-interacting protein 130 (mip130) encodes a subunit of the MuvB core complex. The MuvB core binds to the oncoprotein encoded by Myb and the Rbf-E2f2-Dp tumor suppressor complex, thereby controlling the expression of many genes, including critical regulators of the cell cycle. [Date last reviewed: 2019-03-21]
FBgn0023510	Rbcn-3B	Rabconnectin-3B	Rabconnectin-3B (Rbcn-3B) encodes a protein that is part of a regulatory subunit of the Vacuolar H[+] ATPase required for acidification of intracellular vesicles and the lysosome. It involved in endocytic trafficking and lysosome function, and mutations block Notch signaling in follicle cells and imaginal disc cells. [Date last reviewed: 2019-03-14]
FBgn0023511	Edem1	ER degradation enhancer, mannosidase alpha-like 1	"ER degradation enhancer, mannosidase alpha-like 1 (Edem1) encodes a lectin in the endoplasmic reticulum (ER) lumen that helps to recognize specific misfolded glycoproteins in this cellular compartment for retro-translation to the cytoplasm and ubiquitin-mediated degradation. This process is referred to as ""ER-Associated Degradation"". [Date last reviewed: 2019-03-07]"
FBgn0023512	eIF2Bepsilon	eukaryotic translation initiation factor 2B subunit epsilon	eukaryotic translation initiation factor 2B subunit epsilon (eIF2Bε) encodes a guanyl-nucleotide exchange factor. [Date last reviewed: 2019-08-01]
FBgn0023513	CG14803	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0023514	CG14805	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0023515	Gcna	Germ cell nuclear acidic peptidase	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0023516	Pex5	Peroxin 5	NA
FBgn0023517	Pgam5	Phosphoglycerate mutase 5	NA
FBgn0023518	trr	trithorax-related	trithorax-related (trr) encodes a methyltransferase that trimethylates lysine 4 of the histone encoded by His3. The activity of the product of trr is stimulated by ecdysone and is important for eye development. [Date last reviewed: 2019-03-14]
FBgn0023519	mRpL16	mitochondrial ribosomal protein L16	NA
FBgn0023520	CG3857	NA	NA
FBgn0023521	CG3587	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0023522	CG11596	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0023525	CG3191	NA	NA
FBgn0023526	CG2865	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0023527	CG3071	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0023528	CG2924	NA	NA
FBgn0023529	CG2918	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0023530	CG3740	NA	NA
FBgn0023531	CG32809	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-10-13]
FBgn0023535	arg	arginase	arginase (arg) encodes an enzyme that converts arginine into ornithine. Lack of arg produces a developmental embryonic delay. [Date last reviewed: 2019-03-07]
FBgn0023536	CG3156	NA	NA
FBgn0023537	CG17896	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0023540	CG3630	NA	NA
FBgn0023542	Nmd3	Nonsense-mediated mRNA 3	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0023545	PIG-K	Phosphatidylinositol glycan anchor biosynthesis class K	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0023549	Mct1	Monocarboxylate transporter 1	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0024150	Ac78C	Adenylyl cyclase 78C	Adenylyl cyclase 78C (Ac78C) encodes a member of the adenyly cyclase family of proteins. It converts adenosine triphosphate (ATP) to 3',5'-cyclic AMP (cAMP) and pyrophosphate. In taste receptor neurons, Ac78C product is involved in the sugar taste transduction pathway. [Date last reviewed: 2018-09-20]
FBgn0024177	zpg	zero population growth	NA
FBgn0024183	vig	vasa intronic gene	vasa intronic gene (vig) encodes a protein involved in RNA interference and heterochromatin organization. [Date last reviewed: 2019-09-19]
FBgn0024187	syd	sunday driver	sunday driver (syd) encodes a member of a family of scaffolding proteins that bind to JNK and facilitate its activation. syd is an organ size regulator that functions in Hippo signaling and is essential for Diap1 protein stability and function. [Date last reviewed: 2021-02-04]
FBgn0024188	san	separation anxiety	NA
FBgn0024191	sip1	septin interacting protein 1	NA
FBgn0024194	rasp	rasp	rasp (rasp) encodes an acyltransferase enzyme that adds essential N-terminal palmitate modifications to the secreted signaling domains of the products of hh and spi. The modification of the product of spi appears to increase the local concentration of the ligand by restricting its diffusion. [Date last reviewed: 2019-03-14]
FBgn0024196	robl	roadblock	roadblock (robl) encodes a dynein-associated protein involved in intracellular transport mediated by Dynein. It contributes to dendrite morphogenesis and mushroom body development. [Date last reviewed: 2019-03-14]
FBgn0024222	IKKbeta	I-kappaB kinase beta	I-kappaB kinase β (IKKβ) encodes a a component of the IκB Kinase (IKK) complex together with the product of key. IKK complex participates in the activation of the transcription factor encoded by Rel in the immune deficiency pathway. This pathway regulates the antibacterial response and other less characterized cellular processes. [Date last reviewed: 2019-03-07]
FBgn0024227	aurB	aurora B	aurora B (aurB) encodes a serine-threonine kinase and member of the chromosomal passenger complex. It plays multiple roles in mitosis including the correction of erroneous chromosome-spindle interactions, chromosome condensation, kinetochore assembly, spindle assembly checkpoint and cytokinesis. [Date last reviewed: 2019-03-07]
FBgn0024230	Hs2st	Heparan sulfate 2-O-sulfotransferase	Heparan sulfate 2-O-sulfotransferase (Hs2st) encodes a heparan sulfate modifying enzyme, which transfers a sulfate group to 2-O position of glucuronic or iduronic acid residues of heparan sulfate. Loss of Hs2st function eliminates 2-O sulfation, but increases 6-O sulfation performed by the product of Hs6st. Simultaneous elimination of Hs6st and Hs2st functions disrupts FGF, Wg and Dpp signaling pathways. [Date last reviewed: 2019-03-07]
FBgn0024234	gbb	glass bottom boat	glass bottom boat (gbb) encodes a BMP ligand in the TGF-beta/BMP family of dimeric signaling molecules. It binds to a receptor complex to transduce signal through phosphorylation of the product of Mad. It contributes to maintain stem cell populations, control cell fate specification, proliferation, synapse growth and neuropeptide release. [Date last reviewed: 2018-09-20]
FBgn0024236	foi	fear-of-intimacy	NA
FBgn0024238	Fim	Fimbrin	Fimbrin (Fim) encodes an actin crosslinking protein involved in the remodelling and organisation of the actin cytoskeleton that occurs in processes such as cellularization and cell migration. [Date last reviewed: 2021-01-21]
FBgn0024245	dnt	doughnut on 2	doughnut on 2 (dnt) encodes a Ryk family Wnt receptor-tyrosine kinase-related protein. It can form homo- and heterodimers with the other two Ryks (encoded by Drl-2 and drl) via binding the ligand encoded by Wnt5. dnt and drl products act during embryonic muscle attachment site selection. [Date last reviewed: 2018-09-20]
FBgn0024248	chico	chico	chico (chico) encodes a substrate of the product of InR. As a key component of the Insulin pathway, the chico product plays an essential role in the control of cell size and growth. [Date last reviewed: 2019-06-13]
FBgn0024250	brk	brinker	brinker (brk) encodes a transcriptional repressor that plays important roles in the development of many tissues, including most imaginal discs, where its expression is negatively regulated by Dpp signaling. [Date last reviewed: 2019-03-07]
FBgn0024273	WASp	WASp	WASp (WASp) encodes the homolog of the conserved Wiskott-Aldrich Syndrome family of nucleation promoting factors. It enables the Arp2/3 complex to nucleate polymerization of branched microfilament arrays. It contributes to gastrulation, myoblast fusion, synapse morphology at neuromuscular junctions, sensory organ development, and spermatogenesis. [Date last reviewed: 2019-03-21]
FBgn0024277	trio	trio	trio (trio) encodes a Rho guanine nucleotide exchange factor (GEF) that activates the Rho-family GTPases to regulate actin structure and cell adhesion. The GEF encoded by trio acts in several signaling pathways, including Abl tyrosine kinase and BMP signaling pathways. The product of trio is involved in neural wiring (axon and dendrite patterning and synaptogenesis) and muscle development. [Date last reviewed: 2018-09-20]
FBgn0024285	Srp54	Splicing regulatory protein 54	Srp54 (Srp54) encodes a protein that regulates mRNA alternative splicing, the processing of the mRNA 3'-end and the selection of the transcriptional start site. [Date last reviewed: 2019-09-19]
FBgn0024288	Sox100B	Sox100B	Sox100B (Sox100B) encodes a group E Sox domain transcription factor. It has a role in the development of somatic components of the testis during metamorphosis, where it regulates pigment cell specification. Sox100B shows sexually dimorphic expression in the embryonic gonad. [Date last reviewed: 2018-09-20]
FBgn0024291	Sirt1	Sirtuin 1	Sirtuin 1 (Sirt1) encodes an NAD[+]-dependent deacetylase that functions during euchromatic and heterochromatic gene silencing. Sirt1 product contributes to many biological pathways including neuronal function, apoptosis, metabolism, and development. [Date last reviewed: 2018-09-20]
FBgn0024314	Plap	Phospholipase A2 activator protein	NA
FBgn0024315	Picot	Picot	NA
FBgn0024320	Npc1a	Niemann-Pick type C-1a	Niemann-Pick type C-1a (Npc1a) encodes a cholesterol trafficking protein that contributes to sterol and ecdysone metabolism. It is involved in sperm individualization. [Date last reviewed: 2019-09-26]
FBgn0024321	NK7.1	NK7.1	NA
FBgn0024326	Mkk4	MAP kinase kinase 4	MAP kinase kinase 4 (Mkk4) encodes a mitogen activated protein kinase kinase (MAPKK) involved in the Jun kinase (JNK) pathway. It is directly activated by the MAPKKK encoded by Tak1. Mkk4 product roles include activation of intracellular JNK signalling upon the TNF family ligand encoded by egr and regulation of axon stability. [Date last reviewed: 2018-09-20]
FBgn0024329	Mekk1	Mekk1	Mekk1 (Mekk1) encodes a MAP kinase kinase kinase that regulates the stress response. It is required for resistance to several stresses, notably osmotic shock, and for the regulation of the activity of the product of Duox. [Date last reviewed: 2019-03-14]
FBgn0024330	MED6	Mediator complex subunit 6	NA
FBgn0024352	Stip1	Stress induced phosphoprotein 1	NA
FBgn0024360	MTPAP	mitochondrial poly(A) polymerase	NA
FBgn0024362	Naa30A	N(alpha)-acetyltransferase 30 A	NA
FBgn0024364	CG11417	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0024365	CG12773	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0024366	CG11409	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0024371	E2f2	E2F transcription factor 2	E2F transcription factor 2 (E2f2) encodes a transcription factor that belongs to the E2F gene family. It is a subunit of the DREAM complex, where it forms a heterodimer with the product of Dp to bind to DNA and repress transcription. Among their trancription targets are cell cycle genes and differentiation related genes. [Date last reviewed: 2018-09-20]
FBgn0024432	Dlc90F	Dynein light chain 90F	Dynein light chain 90F (Dlc90F) encodes a light chain subunit of the cytoplasmic dynein complex. The product of Dlc90F forms a dimer that assembles into the cytoplasmic dynein complex and is thought to link dynein to cargos and to adapter proteins that regulate dynein motor function. It contributes to male fertility. [Date last reviewed: 2019-03-07]
FBgn0024491	Bin1	Bicoid interacting protein 1	Bicoid interacting protein 1 (Bin1) interacts with sequence-specific transcription factors (e.g. the product of bcd, Kr, Trl) to help recruit the Sin3A-HDAC1 histone deacetylase co-repressor complex to target genes. The product of Bin1 contributes to axis patterning and embryonic segmentation via transcription regulation. [Date last reviewed: 2019-03-07]
FBgn0024509	Sec13	Secretory 13	NA
FBgn0024510	dlt	discs lost	discs lost (dlt) encodes a protein required for cell survival and cell cycle progression in imaginal discs. [Date last reviewed: 2018-09-20]
FBgn0024542	Neos	Neosin	NA
FBgn0024555	flfl	falafel	falafel (flfl) encodes the regulatory 3 subunit of protein phosphatase 4 (PP4). It targets PP4 to the centromere to regulate kinetochore integrity in mitosis. It is also a key mediator for the localization of the product of mira and associated cell fate determinants during cell cycle. [Date last reviewed: 2019-03-07]
FBgn0024556	mEFTu1	mitochondrial translation elongation factor Tu 1	mitochondrial translation elongation factor Tu 1 (mEFTu1) encodes a protein predicted to function within mitochondria to bring aminoacyl-tRNA to the ribosome during the elongation phase of mRNA translation. [Date last reviewed: 2019-03-14]
FBgn0024558	Dph5	Diphthamide methyltransferase	NA
FBgn0024689	fws	four way stop	four way stop (fws) encodes a protein localised to the Golgi apparatus and involved in several aspects of spermatogenesis. Loss of function of fws causes failure of cleavage furrow ingression in dividing spermatocytes, as well as failure of cell elongation and disruption of the Golgi-based acroblast during spermatid differentiation [Date last reviewed: 2018-09-20]
FBgn0024698	Cpsf160	Cleavage and polyadenylation specificity factor 160	NA
FBgn0024728	Slip1	SLo interacting protein 1	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0024732	Drep1	DNA fragmentation factor-related protein 1	DNA fragmentation factor-related protein 1 (Drep1) encodes a protein that regulates apoptosis. [Date last reviewed: 2018-10-18]
FBgn0024733	RpL10	Ribosomal protein L10	NA
FBgn0024734	PRL-1	PRL-1 phosphatase	PRL-1 phosphatase (PRL-1) encodes a growth inhibitor that counteracts the function of the product of the Src42A oncogene. [Date last reviewed: 2019-03-14]
FBgn0024754	Flo1	Flotillin 1	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0024804	Dbp80	Dead box protein 80	Dead box protein 80 (Dbp80) encodes a putative ATP-dependent RNA helicase (DEAD box helicase), based on sequence similarity to other Dead box proteins, which are involved in mRNA export from the nucleus. [Date last reviewed: 2018-09-20]
FBgn0024806	DIP2	DISCO Interacting Protein 2	DISCO Interacting Protein 2 (DIP2) encodes a member of DIP2 family. It interacts physically with the product of disco in vitro and participates in axonal bifurcation and guidance downstream of the JNK pathway. [Date last reviewed: 2019-03-21]
FBgn0024807	DIP1	DISCO Interacting Protein 1	DISCO Interacting Protein 1 (DIP1) encodes a protein that binds to double-stranded RNA and pre-miRNA. It is involved in the defense response to virus. [Date last reviewed: 2019-09-19]
FBgn0024811	Crk	Crk oncogene	NA
FBgn0024814	Clc	Clathrin light chain	NA
FBgn0024833	AP-1mu	Adaptor Protein complex 1, mu subunit	Adaptor Protein complex 1, μ subunit (AP-1μ) encodes a clathrin adaptor involved in intracellular transport. It controls the trafficking of proteins, including the products of N and spdo. [Date last reviewed: 2019-07-11]
FBgn0024841	Pcd	pterin-4a-carbinolamine dehydratase	NA
FBgn0024846	p38b	p38b MAP kinase	p38b MAP kinase (p38b) encodes the serine/threonine kinase that constitutes MAP kinase signaling cascades. It is phosphorylated by MAPK kinases and phosphorylates various substrates that play roles in stress responses, immune responses and differentiation. [Date last reviewed: 2019-03-14]
FBgn0024887	kin17	kin17	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0024889	Kap-alpha1	karyopherin alpha1	karyopherin α1 (Kap-α1) encodes a protein that is involved in spermatogenesis and the nuclear import of the product of yki. [Date last reviewed: 2019-09-26]
FBgn0024897	b6	b6	NA
FBgn0024909	Taf7	TBP-associated factor 7	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0024912	agt	O-6-alkylguanine-DNA alkyltransferase	O-6-alkylguanine-DNA alkyltransferase (agt) encodes a methylated-DNA-cysteine S-methyltransferase involved in DNA repair. [Date last reviewed: 2019-09-12]
FBgn0024920	Ts	Thymidylate synthase	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0024921	Tnpo	Transportin	Transportin (Tnpo) encodes a protein involved in Hh signalling regulation by mediating the import of the transcription factor encoded by ci into the nucleus. [Date last reviewed: 2019-09-12]
FBgn0024945	NitFhit	Nitrilase and fragile histidine triad fusion protein	Nitrilase and fragile histidine triad fusion protein (NitFhit) encodes a bis(5'-adenosyl)-triphosphatase involved in nucleobase-containing compound metabolism. [Date last reviewed: 2019-09-12]
FBgn0024947	NTPase	NTPase	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0024956	Mat1	Menage a trois 1	Menage a trois 1 (Mat1) encodes a RING finger protein involved in the activation of the kinase encoded by Cdk7 [Date last reviewed: 2019-08-01]
FBgn0024957	Irp-1B	Iron regulatory protein 1B	Iron regulatory protein 1B (Irp-1B) encodes a cytosolic aconitase highly homologous to the product of Irp-1A. [Date last reviewed: 2019-03-07]
FBgn0024958	Irp-1A	Iron regulatory protein 1A	Iron regulatory protein 1A (Irp-1A) encodes a cytosolic aconitase that under iron deficiency (or if cytosolic superoxide is present) loses its iron-sulfur cluster, changes confirmation and binds iron regulatory elements (so far identified on the products of SdhB and Fer1HCH mRNAs). [Date last reviewed: 2019-03-07]
FBgn0024973	CG2701	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0024975	CG2712	NA	NA
FBgn0024980	Syx4	Syntaxin 4	Syntaxin 4 (Syx4) encodes a member of the superfamily of SNARE genes, which mediate membrane fusion. The product of Syx4 is associated with Golgi to plasma membrane transport as well as acting as a plasma membrane t-SNARE to regulate synaptic growth at the neuromuscular junction. [Date last reviewed: 2018-09-20]
FBgn0024983	CG4293	NA	NA
FBgn0024984	CG3457	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0024985	Rilpl	Rab interacting lysosomal protein like	NA
FBgn0024986	CG3719	NA	NA
FBgn0024987	ssx	sister-of-Sex-lethal	NA
FBgn0024991	CG2694	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0024992	Spg7	Paraplegin	NA
FBgn0024993	CG2662	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0024994	Ugalt	UDP-galactose transporter	UDP-galactose transporter (Ugalt) encodes a transporter involved in UDP-N-acetylgalactosamine, UDP-galactose and galactose transmembrane transport. [Date last reviewed: 2019-09-12]
FBgn0024996	eIF2Bbeta	eukaryotic translation initiation factor 2B subunit beta	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0024997	CG2681	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0024998	CG2685	NA	NA
FBgn0025109	Bem46	Bem46	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0025111	Ant2	Adenine nucleotide translocase 2	NA
FBgn0025185	az2	az2	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0025186	ari-2	ariadne 2	NA
FBgn0025335	Cpes	Ceramide phosphoethanolamine synthase	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0025336	CG4882	NA	NA
FBgn0025352	Mtpbeta	Mitochondrial trifunctional protein beta subunit	Mitochondrial trifunctional protein β subunit (Mtpβ) encodes a protein involved in fatty acid beta-oxidation. [Date last reviewed: 2019-09-12]
FBgn0025355	SuUR	Suppressor of Under-Replication	Suppressor of Under-Replication (SuUR) encodes a chromatin binding protein involved in heterochromatin assembly and regulation of the DNA endoreduplication. [Date last reviewed: 2019-09-19]
FBgn0025366	Ip259	Intronic Protein 259	NA
FBgn0025373	Fpps	Farnesyl pyrophosphate synthase	Farnesyl pyrophosphate synthase (Fpps) encodes a protein involved in germ cell migration. [Date last reviewed: 2019-09-12]
FBgn0025381	rush	rush hour	rush hour (rush) encodes an endosome-associated protein that directly binds phosphatidylinositol 3-phosphate (PI3P) and the Rab GDP dissociation inhibitor encoded by Gdi. rush product regulates endosomal trafficking by modulating the activity of Rab proteins. [Date last reviewed: 2018-09-20]
FBgn0025382	Rab27	Rab27	Rab27 (Rab27) encodes a Rab GTPase involved in exosomal secretion. [Date last reviewed: 2019-08-01]
FBgn0025383	CG14780	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0025388	Alms1a	Alstrom syndrome 1a	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0025390	Mur2B	Mucin related 2B	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0025391	Scgdelta	Sarcoglycan delta	Sarcoglycan δ (Scgδ) encodes a transmembrane protein that is required for normal muscle structure and function. It contributes to sarcomere organization and heart contraction. [Date last reviewed: 2018-10-18]
FBgn0025394	inc	insomniac	insomniac (inc) encodes a BTB domain-containing protein that is essential in neurons for normal sleep-wake cycles. [Date last reviewed: 2018-10-18]
FBgn0025455	CycT	Cyclin T	NA
FBgn0025456	CREG	Cellular Repressor of E1A-stimulated Genes	Cellular Repressor of E1A-stimulated Genes (CREG) encodes an essential protein located in lysosomes and related subcellular compartments. [Date last reviewed: 2018-10-18]
FBgn0025457	Bub3	Bub3	Bub3 (Bub3) encodes a protein that functions in the spindle assembly checkpoint (SAC) pathway. This mitotic checkpoint pathway inhibits the APC/C complex and hence the transition from metaphase to anaphase, as long as there are free kinetochores that are not yet attached to the mitotic spindle in the cell. The product of Bub3 is localized at the kinetochore during mitosis with maximal levels observed at free kinetochores. Together with other SAC proteins it forms mitotic checkpoint complexes that bind and inhibit the APC/C. [Date last reviewed: 2019-03-07]
FBgn0025463	Bap60	Brahma associated protein 60kD	Brahma associated protein 60kD (Bap60) encodes a protein required for Brahma complex function. It represses neuroblast proliferation and regulates heterochromatin assembly. [Date last reviewed: 2019-08-01]
FBgn0025469	slv	saliva	NA
FBgn0025519	fidipidine	fidipidine	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0025525	bab2	bric a brac 2	bric a brac 2 (bab2) encodes a transcriptional regulator that functions partially redundantly with the product of bab1. It is part of the conserved proximal-distal gene regulatory network module. It contributes to pattern formation, ovary morphogenesis, abdominal pigmentation and olfactory receptor neuron fate diversity. [Date last reviewed: 2019-03-07]
FBgn0025549	unc-119	unc-119	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0025558	CG4101	NA	NA
FBgn0025571	SF1	Splicing factor 1	NA
FBgn0025574	Pli	Pellino	Pellino (Pli) encodes a RING-domain-containing ubiquitin E3 ligase that coordinates with ubiquitin-activating (E1) and ubiquitin-conjugating (E2) enzymes to degrade target proteins. It functions as a negative regulator of the Toll-mediated innate immunity pathway. [Date last reviewed: 2018-10-18]
FBgn0025582	eIF3e	eukaryotic translation initiation factor 3 subunit e	eukaryotic translation initiation factor 3 subunit e (eIF3e) encodes a component of the translation initiation complex and is a positive regulator of cullin neddylation, which is required for Cullin-ring ubiquitin ligase activity. It also regulates spindle assembly, microtubule dynamics and mitotic progression. [Date last reviewed: 2018-10-18]
FBgn0025592	Gk1	Glycerol kinase 1	NA
FBgn0025608	Faf2	Fas-associated factor 2	Fas-associated factor 2 (Faf2) encodes a putative E3 ligase adaptor protein with a proteosome dependent function. [Date last reviewed: 2019-03-07]
FBgn0025615	Torsin	Torsin	Torsin (Torsin) encodes an AAA-ATPase that is implicated in the export of large ribonuclear protein particles through the nuclear membrane. It regulates dopamine levels. [Date last reviewed: 2018-10-18]
FBgn0025621	CG16989	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0025624	CG4025	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0025625	Sik2	Salt-inducible kinase 2	Salt-inducible kinase 2 (Sik2) encodes a serine/threonine kinase that is activated by the product of Lkb1. It regulates lipid storage and energy homeostasis by controlling the activity of cAMP-response element-binding protein (CREB)-regulated transcription coactivator (CRTC). [Date last reviewed: 2019-03-14]
FBgn0025626	CG4281	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0025628	CG4199	NA	NA
FBgn0025629	CG4045	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0025630	Rtca	RNA 3'-terminal phosphate cyclase	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0025631	moody	moody	NA
FBgn0025632	CG4313	NA	NA
FBgn0025633	CG13366	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0025634	CG13367	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0025635	CG17829	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0025637	SkpA	SKP1-related A	SKP1-related A (SkpA) encodes a subunit of Skp, Cullin, F-box (SCF)-containing ubiquitin ligase complexes. It regulates centrosome duplication, chromatin condensation, cell cycle progression, cell polarity, dendrite pruning and endoreduplication. [Date last reviewed: 2019-03-14]
FBgn0025638	Roc1a	Regulator of cullins 1a	Regulator of cullins 1a (Roc1a) encodes a C2H2 type zinc finger protein and component of several Cullin-Ring E3 ubiquitin ligase complexes. It binds directly to the Cullin subunit within the CRL complex and functions to recruit ubiquitin-charged E2 proteins. [Date last reviewed: 2019-03-14]
FBgn0025639	Hmt4-20	Histone methyltransferase 4-20	Histone methyltransferase 4-20 (Hmt4-20) encodes a di- and trimethyltransferase, acting on the lysine 20 residue of monomethylated Histone H4. [Date last reviewed: 2018-10-18]
FBgn0025640	CG13369	NA	NA
FBgn0025641	DAAM	Dishevelled Associated Activator of Morphogenesis	Dishevelled Associated Activator of Morphogenesis (DAAM) encodes a formin type of actin assembly factor regulated by Rho GTPases. It plays a role in tracheal tube length regulation, tracheal cuticle pattern formation, growth cone filopodia formation, sarcomerogenesis and axonal growth regulation in embryonic and mushroom body neurons. [Date last reviewed: 2019-03-07]
FBgn0025642	CG32812	NA	NA
FBgn0025674	CycK	Cyclin K	Cyclin K (CycK) encodes a Cyclin-homologous subunit that forms a complex with the transcriptional kinase encoded by Cdk12. This complex phosphorylates the carboxy terminal domain of the large subunit of RNA polymerase II (encoded by Polr2A) and contributes to pre-mRNA processing, transcription and chromatin structure. [Date last reviewed: 2018-10-18]
FBgn0025676	CkIIalpha-i3	CKII-alpha subunit interactor-3	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0025678	CaBP1	calcium-binding protein 1	calcium-binding protein 1 (CaBP1) encodes a protein that resides in the lumen of the endoplasmic reticulum. It seems to be relocated outside cells during apoptosis and involved in the phagocytosis of apoptotic cells. [Date last reviewed: 2019-03-07]
FBgn0025681	CG3558	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-10-13]
FBgn0025682	scf	supercoiling factor	supercoiling factor (scf) encodes two polypeptides: DCB45 and its N-teminally truncated form Scf. Scf is a nuclear protein that introduces negative supercoils into DNA in conjunction with topoisomerase II. DCB45 is an endoplasmic reticulum-resident protein. [Date last reviewed: 2019-03-14]
FBgn0025684	MFS18	Major Facilitator Superfamily Transporter 18	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0025693	ZnT41F	Zinc transporter 41F	NA
FBgn0025697	santa-maria	scavenger receptor acting in neural tissue and majority of rhodopsin is absent	scavenger receptor acting in neural tissue and majority of rhodopsin is absent (santa-maria) encodes a class B scavenger receptor that contributes to the conversion of carotenoids to vitamin A. It is involved in phototransduction and thermotaxis. [Date last reviewed: 2019-09-26]
FBgn0025700	CG5885	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0025702	Srpk79D	Serine-arginine protein kinase at 79D	Serine-arginine protein kinase at 79D (Srpk79D) is required to prevent the formation of axonal protein aggregates containing the active zone-protein encoded by brp. [Date last reviewed: 2019-03-14]
FBgn0025716	Bap55	Brahma associated protein 55kD	Brahma associated protein 55kD (Bap55) encodes a member of two chromatin remodeling complexes. As part of the Brahma complex, it is needed for cell growth and survival in the wing imaginal disc; as a member of the TIP60 complex, it is thought to regulate dendrite wiring specificity in olfactory projection neurons. [Date last reviewed: 2018-10-18]
FBgn0025720	Ate1	Arginyltransferase 1	Arginyltransferase 1 (Ate1) encodes a putative arginyltransferase involved in protein arginylation based on orthology. [Date last reviewed: 2019-03-07]
FBgn0025724	beta'COP	Coat Protein (coatomer) beta'	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0025725	alphaCOP	Coat Protein (coatomer) alpha	NA
FBgn0025726	unc-13	unc-13	unc-13 (unc-13) encodes a protein involved in synaptic vesicle exocytosis. [Date last reviewed: 2019-09-19]
FBgn0025739	pon	partner of numb	partner of numb (pon) encodes a protein that functions upstream of the cell fate determinant encoded by numb during asymmetric cell divisions. It contributes to asymmetric localization of the numb product and the subsequent suppression of Notch signaling. [Date last reviewed: 2018-10-18]
FBgn0025740	PlexB	Plexin B	Plexin B (PlexB) encodes a transmembrane receptor for ligands including semaphorins, which signals via RhoGTPases. It can signal both attractive and repulsive axon guidance. [Date last reviewed: 2019-03-14]
FBgn0025741	PlexA	Plexin A	Plexin A (PlexA) encodes a transmembrane receptor for Semaphorin ligands encoded by Sema1a and Sema1b. The intracellular region of this receptor has GTPase activating protein (GAP) activity on Ras/Rap small GTPases. The signaling by the product of PlexA alters actin, microtubules and cell adhesion in developmental processes such as axon guidance. [Date last reviewed: 2019-03-14]
FBgn0025742	mtm	myotubularin	myotubularin (mtm) encodes a phosphatidylinositol-3-phosphatase that, together with the products of Sbf and Rab21, regulates macrophage protrusion formation. It is involved in cortical actin cytoskeleton organization, chromosome segregation and endocytic recycling. [Date last reviewed: 2019-03-14]
FBgn0025743	mbt	mushroom bodies tiny	NA
FBgn0025777	homer	homer	homer (homer) encodes a protein that acts as an adaptor protein binding to group I metabotropic glutamate receptors and other intracellular signaling proteins. It contributes to regulation of sleep, locomotor activity and ethanol tolerance. [Date last reviewed: 2019-03-07]
FBgn0025781	Cdc16	Cell division cycle 16	Cell division cycle 16 (Cdc16) encodes an essential subunit of the anaphase promoting complex/cyclosome (APC/C). Together with other subunits, it forms a functional subcomplex of the APC/C that binds to the product of shtd and is likely to be involved in activator and substrate binding. [Date last reviewed: 2019-03-07]
FBgn0025790	TBPH	TAR DNA-binding protein-43 homolog	TAR DNA-binding protein-43 homolog (TBPH) encodes an RNA-binding protein that belongs to the hnRNP family. It contributes to synaptic growth of motor neurons and glial wrapping. [Date last reviewed: 2019-03-14]
FBgn0025800	Smox	Smad on X	Smad on X (Smox) encodes the primary transcription factor that mediates Activin signalling. Upon phosphorylation by the receptor encoded by babo, it forms a complex with the co-Smad protein encoded by Med. This complex translocates to the nucleus where it regulates expression of target genes. [Date last reviewed: 2018-10-18]
FBgn0025802	Sbf	SET domain binding factor	NA
FBgn0025807	Rad9	Rad9	Rad9 (Rad9) encodes a protein that, together with the Rad1 and Hus1-like products, forms the 9-1-1 checkpoint protein complex. This complex plays a central role in the DNA damage-induced checkpoint response. [Date last reviewed: 2018-10-18]
FBgn0025808	Rad17	Rad17	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0025809	Paf-AHalpha	Platelet-activating factor acetylhydrolase alpha	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0025814	Mgstl	Microsomal glutathione S-transferase-like	NA
FBgn0025815	Mcm6	Minichromosome maintenance 6	Minichromosome maintenance 6 (Mcm6) encodes a subunit of the hetero-hexameric mini-chromosome maintenance (MCM) Complex, which is the eukaryotic replicative DNA helicase. MCM complex requires association with CDC45L and the GINS complex for full helicase activity. [Date last reviewed: 2019-03-14]
FBgn0025820	JTBR	JTBR	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0025825	HDAC3	Histone deacetylase 3	Histone deacetylase 3 (HDAC3) encodes a histone deacetylase involved in chromatin silencing. It controls cell growth through apoptosis suppression by regulating transcription of hid. [Date last reviewed: 2019-03-07]
FBgn0025830	IntS8	Integrator 8	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0025832	Fen1	Flap endonuclease 1	NA
FBgn0025836	RhoGAP1A	Rho GTPase activating protein at 1A	Rho GTPase activating protein at 1A (RhoGAP1A) encodes a protein involved in Golgi organization and cell growth inhibition. [Date last reviewed: 2019-07-11]
FBgn0025839	ND-B14.5A	NADH dehydrogenase (ubiquinone) B14.5 A subunit	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0025864	Crag	Calmodulin-binding protein related to a Rab3 GDP/GTP exchange protein	Calmodulin-binding protein related to a Rab3 GDP/GTP exchange protein (Crag) encodes a guanine exchange factor for the products of Rab10 and Rab11. It is involved in the exclusive secretion of basement membrane proteins on the basal side of cells. [Date last reviewed: 2019-03-07]
FBgn0025865	Cortactin	Cortactin	NA
FBgn0025866	CalpB	Calpain-B	NA
FBgn0025874	Meics	Meiotic central spindle	NA
FBgn0025885	Inos	myo-inositol-1-phosphate synthase	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0025936	Eph	Eph receptor tyrosine kinase	Eph receptor tyrosine kinase (Eph) encodes an axon guidance molecule involved in the development of the nervous system. It also contributes to shaping the antero-posterior compartment boundary of the wing disc. [Date last reviewed: 2019-06-13]
FBgn0026015	Top3beta	Topoisomerase 3beta	Topoisomerase 3β (Top3β) encodes an RNA topoisomerase that participates in both transcription and translation. It promotes transcription by being recruited by the product of Tdrd3, an epigenetic reader recognizing dimethylarginine motifs in core histones. It contributes to translation by complexing with the product of Fmr1, an RNA-binding protein deficient in fragile X mental retardation syndrome. [Date last reviewed: 2019-03-14]
FBgn0026056	Rlip	Ral interacting protein	Ral interacting protein (Rlip) encodes a Rho GTPase activating protein involved in receptor-mediated endocytosis. [Date last reviewed: 2019-08-01]
FBgn0026059	Mhcl	Myosin heavy chain-like	Myosin heavy chain-like (Mhcl) encodes a protein that interacts with the product of rols during myoblast fusion. [Date last reviewed: 2019-03-14]
FBgn0026076	UBL3	Ubiquitin like 3	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0026079	Nsun2	NOP2-Sun domain family, member 2	NA
FBgn0026080	Tip60	Tat interactive protein 60kDa	Tat interactive protein 60kDa (Tip60) encodes a lysine acetyltransferase that acetylates histone proteins to regulate chromatin packaging and epigenetic gene control. It also acetylates non-histone proteins, and plays a role in apoptosis, DNA repair and various neural processes. [Date last reviewed: 2019-03-14]
FBgn0026083	tyf	twenty-four	twenty-four (tyf) encodes a protein that forms a complex together with the products of Atx2 and Lsm12. This complex binds per mRNA and activates its translation to sustain circadian rhythms. The tyf product is also involved in immune defense against Listeria monocytogenes infection. [Date last reviewed: 2018-10-18]
FBgn0026084	cib	ciboulot	ciboulot (cib) encodes an actin binding protein involved in brain development and the remodeling of the larval central nervous system. [Date last reviewed: 2019-09-12]
FBgn0026085	dgt4	dim gamma-tubulin 4	NA
FBgn0026086	Adar	Adenosine deaminase acting on RNA	Adenosine deaminase acting on RNA (Adar) encodes an RNA editing enzyme. It is involved in behaviour, glucose metabolism and response to several stresses such as heat, hypoxia and oxidative stress. [Date last reviewed: 2019-03-07]
FBgn0026088	CG14818	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0026089	CG14817	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0026090	Lamtor5	Late endosomal/lysosomal adaptor, MAPK and MTOR activator 5	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0026143	Cdc45	Cell division cycle 45	CDC45L (CDC45L) encodes a protein that contributes to 3'-5' DNA helicase activity of the Cdc45/Mcm2-7/GINS complex. It is involved in chromosome condensation and the regulation of the mitotic G1/S transition. [Date last reviewed: 2019-09-19]
FBgn0026147	TTLL4A	Tubulin tyrosine ligase-like 4A	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0026148	CG12253	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0026149	BCL7-like	BCL7-like	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0026150	ApepP	Aminopeptidase P	NA
FBgn0026160	tna	tonalli	tonalli (tna) is an essential gene that encodes several isoforms, including Tna-A, which physically associates with subunits of the Brahma chromatin remodeling complex and is involved in transcriptional activation. [Date last reviewed: 2018-10-18]
FBgn0026175	SkpC	SKP1-related C	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0026179	siz	schizo	schizo (siz) encodes an Arf1 guanine nucleotide exchange factor involved in commissural axon guidance and myoblast fusion. [Date last reviewed: 2019-03-14]
FBgn0026181	Rok	Rho kinase	Rho kinase (Rok) encodes a kinase that, when activated by the GTP form of the product of Rho1, phosphorylates and modulates cytoskeletal proteins, particularly myosin II. Dynamic regulation of this kinase in subcellular locales influences cell polarization, movement, and shape during interphase and mitosis. [Date last reviewed: 2019-03-14]
FBgn0026189	promL	prominin-like	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0026192	par-6	par-6	par-6 (par-6) encodes a scaffold protein that forms a complex with the products of baz and aPKC and with other cortical, cytoskeletal and regulatory proteins. It is involved in cell polarization, actin-based protrusion formation and tracheal branching. [Date last reviewed: 2019-06-13]
FBgn0026196	nop5	nop5	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0026197	lncRNA:noe	long non-coding RNA:noe	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0026199	myo	myoglianin	myoglianin (myo) encodes a protein expressed primarily in muscle and glia cells. Mutations in myo affect neuronal remodeling during metamorphosis by failing to activate EcR expression in the remodeling neurons. [Date last reviewed: 2018-10-18]
FBgn0026206	mei-P26	meiotic P26	meiotic P26 (mei-P26) encodes a protein involved in meiosis, germline differentiation and spermatogenesis. [Date last reviewed: 2019-07-11]
FBgn0026207	mbo	members only	members only (mbo) encodes a nucleoporin involved in immune response transduction by mediating the nuclear translocation of the product of Mad. [Date last reviewed: 2019-06-27]
FBgn0026238	gus	gustavus	gustavus (gus) encodes a cullin-RING ubiquitin E3 ligase specificity receptor. It interacts genetically and physically with the product of Cul5, and putatively regulates stability of target proteins including the one encoded by vas. It is involved in oogenesis and germ cell maintenance. [Date last reviewed: 2019-03-07]
FBgn0026239	gukh	GUK-holder	GUK-holder (gukh) encodes a protein that regulates spindle orientation in neuroblasts via direct interaction with microtubules and the tumor suppressors encoded by dlg1 and scrib. It also plays a role in polarizing fate determinants, such as the product of mira. [Date last reviewed: 2018-10-18]
FBgn0026250	eIF1A	eukaryotic translation initiation factor 1A	eukaryotic translation initiation factor 1A (eIF1A) encodes a protein required for mRNA translation. It is involved in 43S pre-initiation complex assembly, ensuring correct AUG start codon selection, and its dissociation from the 40S ribosome subunit is considered crucial for start codon recognition. [Date last reviewed: 2018-10-18]
FBgn0026252	msk	moleskin	moleskin (msk) encodes an importin that contributes to protein import into the nucleus. It is involved in eye development, muscle attachment and wing cell fate specification. [Date last reviewed: 2019-09-26]
FBgn0026257	cav	caravaggio	caravaggio (cav) is a fast evolving gene that encodes HP1/ORC Associated Protein (HOAP). HOAP is a DNA binding protein strongly enriched at chromosome ends and required for telomere capping. [Date last reviewed: 2019-03-07]
FBgn0026259	eIF5B	eukaryotic translation initiation factor 5B	NA
FBgn0026261	bonsai	bonsai	bonsai (bonsai) encodes a mitochondrial small ribosomal protein that belongs to the universal S15 ribosomal protein US15m family. It is involved in growth regulation. [Date last reviewed: 2018-10-18]
FBgn0026262	Taf3	TBP-associated factor 3	TBP-associated factor 3 (Taf3) encodes a protein that interacts with the transcription factor encoded by Trl and is involved in transcriptional activation. [Date last reviewed: 2019-08-01]
FBgn0026263	bip1	bip1	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0026309	aft	adrift	adrift (aft) encodes a protein involved in tracheal development. [Date last reviewed: 2019-09-12]
FBgn0026313	X11L	X11L	X11L (X11L) encodes a scaffolding protein that is important for eye development. It interacts with the products of rst and Appl and is required for targeting several proteins to cell membranes. [Date last reviewed: 2019-03-21]
FBgn0026315	Ugt35A1	UDP-glycosyltransferase family 35 member A1	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0026316	Ubc10	Ubiquitin conjugating enzyme 10	Ubiquitin conjugating enzyme 10 (Ubc10) encodes an E2 ubiquitin conjugating enzyme that interacts with the E3 ubiquitin ligase encoded by ari-1. Both jointly ubiquitylate isoform A of the ecdysone receptor encoded by EcR. [Date last reviewed: 2019-03-14]
FBgn0026317	Tsc1	Tsc1	Tsc1 (Tsc1) encodes a tumour suppressor protein that forms a complex with the product of gig. They control cellular growth via antagonizing insulin and TOR signalling pathways. [Date last reviewed: 2019-03-14]
FBgn0026319	Traf4	TNF-receptor-associated factor 4	TNF-receptor-associated factor 4 (Traf4) encodes an adapter protein thought to bind the TNF receptor and activate downstream signaling. However, it also has TNF independent roles, especially with respect to morphogenesis. The product of Traf4 interacts with and localizes polarity and adherens junction proteins such as the products of baz and arm respectively. It is required for normal embryonic development, cell death, and cell growth. [Date last reviewed: 2019-03-14]
FBgn0026323	Tak1	TGF-beta activated kinase 1	TGF-β activated kinase 1 (Tak1) encodes a MAP kinase kinase kinase that functions downstream of the products of imd, Fadd and Diap2. It also functions upstream of the IKK complex in the Imd pathway, a pathway regulating the antibacterial response and other less characterized cellular processes. Upon activation the product of imd, the product of Tak1 can also activate the JNK pathway at the level of the JNK Kinase encoded by bsk in certain cell types. It is also an intracellular signaling component of the Grindelwald-Eiger pathway. [Date last reviewed: 2019-03-14]
FBgn0026324	Taf10b	TBP-associated factor 10b	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0026326	Mad1	Mitotic arrest-deficient 1	Mitotic arrest-deficient 1 (Mad1) encodes a conserved, essential component of the spindle checkpoint. During mitosis, it is recruited to unattached kinetochores, where it binds the product of mad2 and promotes the assembly of the products of mad2 and fzy into the mitotic checkpoint complex. During interphase, Mad1 is intranuclear, bound to the product of mad2, and associated primarily with the nuclear pore complex. [Date last reviewed: 2019-03-14]
FBgn0026361	Septin5	Septin 5	Septin 5 (Septin5) encodes a member of the septin family of GTP-binding proteins. Septins form hetero-oligomeric filaments and rings that have roles in cytokinesis, cell polarity and membrane rigidity. Septin5 is not essential for development, but mutants display a synthetic lethal pupal phenotype when combined with mutations in its paralog Septin2. [Date last reviewed: 2018-10-18]
FBgn0026369	Sara	Smad anchor for receptor activation	Smad anchor for receptor activation (Sara) encodes an endosomal protein involved in asymmetric stem cell division, intestinal stem cell homeostasis and stem cell fate determination. [Date last reviewed: 2019-09-26]
FBgn0026371	SAK	Sak kinase	Sak kinase (SAK) encodes a serine/threonine protein kinase member of the Polo-like kinase family. It phosphorylates centrosomal proteins and self-regulates by autophosphorylation. It is required for centriole biogenesis and formation of the basal bodies of cilia and flagella. [Date last reviewed: 2019-03-14]
FBgn0026372	RpL23A	Ribosomal protein L23A	Ribosomal protein L23A (RpL23A) encodes an essential ribosomal RNA binding protein of the large ribosomal subunit involved in protein synthesis. [Date last reviewed: 2018-10-18]
FBgn0026373	Polr2C	RNA polymerase II subunit C	NA
FBgn0026374	Rhp	Rhophilin	NA
FBgn0026375	RhoGAPp190	Rho GTPase activating protein p190	Rho GTPase activating protein p190 (RhoGAPp190) encodes a Rho GTPase activating protein that binds the semaphorin receptor and regulates axonogenesis. [Date last reviewed: 2019-08-01]
FBgn0026376	Rgl	Ral guanine nucleotide dissociation stimulator-like	NA
FBgn0026378	Rep	Rab escort protein	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0026379	Pten	Phosphatase and tensin homolog	Phosphatase and tensin homolog (Pten) encodes a dual lipid and protein phosphatase that primarily counters the effects of the insulin-regulated lipid kinase, encoded by Pi3K92E. It inhibits cell growth, cell proliferation and cellular events controlling cytoskeletal and junctional rearrangements. [Date last reviewed: 2018-10-18]
FBgn0026380	Prosbeta3	Proteasome beta3 subunit	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0026393	Or43b	Odorant receptor 43b	Odorant receptor 43b (Or43b) encodes a multi-transmembrane chemoreceptor that mediates response to volatile chemicals. [Date last reviewed: 2019-03-14]
FBgn0026400	Noa36	Noa36	NA
FBgn0026401	Nipped-B	Nipped-B	Nipped-B (Nipped-B) encodes a protein that interacts with the product of Mau2 to form the kollerin complex, which topologically loads the cohesin ring complex onto chromosomes. The product of Nipped-B and cohesin participate in transcriptional regulation and DNA repair. [Date last reviewed: 2019-03-14]
FBgn0026402	NiPp1	Nuclear inhibitor of Protein phosphatase 1	Nuclear inhibitor of Protein phosphatase 1 (NiPp1) encodes a PP1 phosphatase inhibitor involved in axon guidance. [Date last reviewed: 2019-09-26]
FBgn0026404	Dronc	Death regulator Nedd2-like caspase	Death regulator Nedd2-like caspase (Dronc) encodes an initiator caspase that is essential for caspase-dependent cell death. It is also implicated in the DNA damage response, sperm differentiation and cell specification. [Date last reviewed: 2018-10-18]
FBgn0026409	Mpcp2	Mitochondrial phosphate carrier protein 2	NA
FBgn0026415	Idgf4	Imaginal disc growth factor 4	NA
FBgn0026417	Hus1-like	Hus1-like	Hus1-like (Hus1-like) encodes a protein that together with proteins encoded by Rad1 and Rad9 form the 9-1-1 checkpoint protein complex. This complex plays a central role in the DNA damage-induced checkpoint response. [Date last reviewed: 2018-09-27]
FBgn0026418	Hsc70Cb	Hsc70Cb	Hsc70Cb (Hsc70Cb) encodes an HSP110 family protein that interacts physically with the product of DnaJ-1 as a chaperone of misfolded proteins. It functions together with the product of DnaJ-1 to prevent the toxicity of aggregation-prone proteins. [Date last reviewed: 2019-03-07]
FBgn0026427	Su(var)2-HP2	Su(var)2-HP2	Su(var)2-HP2 (Su(var)2-HP2) encodes a chromosomal protein that interacts with the product of Su(var)205 and is found most closely associated with centromeric heterochromatin, telomeres and the fourth chromosome. Lack of Su(var)2-HP2 can cause mitotic abnormalities and suppress position-effect variegation. [Date last reviewed: 2019-09-26]
FBgn0026428	HDAC6	Histone deacetylase 6	Histone deacetylase 6 (HDAC6) encodes a cytosolic deacetylase that functions as a key modulator of proteostasis by mediating ubiquitin-proteasomal and lysosomal degradation of native and/or misfolded proteins. [Date last reviewed: 2018-09-27]
FBgn0026430	Grip84	Gamma-tubulin ring protein 84	NA
FBgn0026431	Grip75	Grip75	NA
FBgn0026432	Grip163	Grip163	Grip163 (Grip163) encodes a gamma-tubulin binding protein involved in the mitotic cell cycle. [Date last reviewed: 2019-09-12]
FBgn0026433	Grip128	Grip128	Grip128 (Grip128) encodes a component of the Gamma-tubulin ring complex, which is a potent microtubule nucleator in eukaryotic cells essential for successful chromosome segregation and cell division. [Date last reviewed: 2019-03-07]
FBgn0026439	Eaat1	Excitatory amino acid transporter 1	Excitatory amino acid transporter 1 (Eaat1) encodes a transmembrane protein with a glutamate:sodium symporter activity. It is regulated by Notch signalling and contributes to larval locomotion and lifespan. [Date last reviewed: 2019-03-07]
FBgn0026441	ear	ENL/AF9-related	ENL/AF9-related (ear) encodes a transcription factor that is a component of the super elongation complex (SEC), which regulates transcription by RNA Polymerase II. It also interacts with the histone methyltransferase encoded by gpp in the Dot1 complex (DotCom), which modifies chromatin structure by methylating histone H3 on lysine 79. [Date last reviewed: 2019-03-07]
FBgn0026479	Drp1	Dynamin related protein 1	Dynamin related protein 1 (Drp1) encodes a dynamin-like GTPase that mediates mitochondrial fission through a process that involves translocation to the mitochondrial outer membrane and oligomerization. It is required for normal neuronal development and maintenance of postmitotic neuronal function and viability. [Date last reviewed: 2018-09-27]
FBgn0026533	Dek	Dek	Dek (Dek) encodes a DNA binding protein involved in DNA repair and heterochromatin integrity. [Date last reviewed: 2018-09-27]
FBgn0026562	SPARC	Secreted protein, acidic, cysteine-rich	"Secreted protein, acidic, cysteine-rich (SPARC) encodes a small calcium and growth factor-binding secreted glycoprotein that is enriched in basement membranes. During cell competition, it is expressed in ""loser"" cells so they can avoid apoptosis mediated by the products of fwe and azot. [Date last reviewed: 2018-09-27]"
FBgn0026566	CG1307	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0026570	CG5704	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0026573	ADD1	ADD domain-containing protein 1	ADD domain-containing protein 1 (ADD1) encodes a strong Heterochromatin Protein 1 interactor that interacts with methylated H3K9 silencing marks in heterochromatin. [Date last reviewed: 2019-03-07]
FBgn0026575	hang	hangover	hangover (hang) encodes a nuclear zinc finger protein that is expressed in adult fly brain neurons. Lack of hang produces a reduction of Fas2 expression. Its roles include life span, bouton growth at the neuromuscular junction and regulation of cellular stress in response to ethanol, heat and paraquat. [Date last reviewed: 2019-03-07]
FBgn0026576	Pisd	Phosphatidylserine decarboxylase	NA
FBgn0026577	CG8677	NA	CG8677 encodes a protein that dimerizes with the product of Iswi to form a chromatin remodeling factor RSF (remodeling and spacing factor). RSF is involved in silent chromatin formation via replacement of the product of His2Av. [Date last reviewed: 2019-03-07]
FBgn0026582	Hmg-2	High mobility group protein 2	High mobility group protein 2 (Hmg-2) encodes a member of the non-histone chromosomal high-mobility group protein family. These proteins associate with with chromatin and are ubiquitously distributed in the nucleus of eukaryotic cells. The product of Hmg-2 binds to DNA in a non-sequence specific fashion to induce structural changes in DNA that include bending and unwinding that in turn, promote DNA flexibility. [Date last reviewed: 2019-09-26]
FBgn0026593	CG5707	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0026597	Axn	Axin	Axin (Axn) encodes the key scaffolding protein for the canonical Wnt signalling pathway. In the absence of signal, it targets the product of arm for proteolysis inhibiting Wnt signalling. In the presence of signal, it forms a part of the membrane activation complex, disrupting the product of arm degradation. This pathway play roles in cell proliferation (imaginal disc), differentiation (embryonic patterning), death and stemness. [Date last reviewed: 2019-03-07]
FBgn0026598	Apc2	Adenomatous polyposis coli 2	Adenomatous polyposis coli 2 (Apc2) encodes one of two Drosophila APC family proteins. It is a key negative regulator of Wingless signaling, as a critical component of the destruction complex that phosphorylates beta-catenin and thus targets it for ubiquitination and proteasomal destruction. It is the primary APC family member during embryonic development, and functions redundantly with the product of Apc in adult development. [Date last reviewed: 2019-03-07]
FBgn0026602	Adk3	Adenosine kinase 3	NA
FBgn0026616	alpha-Man-IIb	alpha-Mannosidase class II b	α-Mannosidase class II b (α-Man-IIb) encodes a mannosidase involved in cellular encapsulation response and glycoprotein metabolism. [Date last reviewed: 2019-09-12]
FBgn0026619	Taz	Tafazzin	Tafazzin (Taz) encodes a mitochondrial phospholipid-lysophospholipid transacylase that exchange acyl groups between cardiolipin molecules and other phospholipids. It plays a critical role in maintaining a normal cardiolipin composition required for optimal mitochondrial function. [Date last reviewed: 2019-03-14]
FBgn0026620	tacc	transforming acidic coiled-coil protein	transforming acidic coiled-coil protein (tacc) encodes a centrosomal protein that helps to stabilize microtubules. It seems to influence microtubules indirectly, primarily through its interaction with the product of msps. It is also phosphorylated by the product of aurA, and this activates its ability to stabilize microtubules. [Date last reviewed: 2019-03-14]
FBgn0026630	nes	nessy	nessy (nes) encodes a lysophospholipid acyltransferase that is required redundantly with the product of oys for germ cell migration and spermatid individualization. [Date last reviewed: 2019-03-14]
FBgn0026634	Cog2	Component of oligomeric golgi complex 2	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0026666	MagR	Magnetic receptor	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0026679	IntS4	Integrator 4	NA
FBgn0026702	Pop1	POP1 ribonuclease P/MRP subunit	NA
FBgn0026713	Prp16	pre-mRNA processing factor 16	pre-mRNA processing factor 16 (Prp16) encodes a protein involved in alternative mRNA splicing regulation. [Date last reviewed: 2019-09-26]
FBgn0026718	Agpat2	1-Acylglycerol-3-phosphate O-acyltransferase 2	NA
FBgn0026721	fat-spondin	fat-spondin	NA
FBgn0026722	drosha	drosha	drosha (drosha) encodes a protein that contributes to miRNA processing. It is involved in salivary gland histolysis and oocyte development. [Date last reviewed: 2019-09-19]
FBgn0026737	CG6171	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0026738	CG7857	NA	NA
FBgn0026741	mRpL18	mitochondrial ribosomal protein L18	NA
FBgn0026749	Yippee	Yippee	NA
FBgn0026751	XRCC1	XRCC1	NA
FBgn0026761	Trap1	Trap1	Trap1 (Trap1) encodes a mitochondrial chaperone protein of the heat shock protein (HSP90) family. It shows an ATPase activity and is involved in neurodegeneration associated with mitochondrial dysfunction. [Date last reviewed: 2019-03-14]
FBgn0026777	Rad23	Rad23	Rad23 (Rad23) encodes an evolutionarily conserved member of the proteasome-associated proteins. It acts as a shuttle -or bridge- protein helping ubiquitinated proteins to interact with the proteasome, which in turn regulates their turnover. [Date last reviewed: 2018-09-27]
FBgn0026787	Nhe1	Na[+]/H[+] hydrogen exchanger 1	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0026869	Tdg	Thymine DNA glycosylase	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0026872	CG14777	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0026873	MED18	Mediator complex subunit 18	NA
FBgn0026874	CG13358	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0026876	CG11403	NA	NA
FBgn0026879	CG13364	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-10-13]
FBgn0027052	STUB1	STIP1 homology and U-box containing protein 1	STIP1 homology and U-box containing protein 1 (STUB1) encodes a ubiquitin protein ligase involved in insulin signaling pathway regulation and protein ubiquitination. [Date last reviewed: 2019-07-11]
FBgn0027053	CSN5	COP9 signalosome subunit 5	COP9 signalosome subunit 5 (CSN5) encodes the subunit 5 of the COP9 signalosome (CSN). The CSN plays a central role in the regulation of E3-cullin RING ubiquitin ligases. The product of CSN5 is an isopeptidase that deNEDDylates the cullin subunit of E3-cullin RING ubiquitin ligases. [Date last reviewed: 2019-03-07]
FBgn0027054	CSN4	COP9 signalosome subunit 4	COP9 signalosome subunit 4 (CSN4) encodes the subunit 4 of the COP9 signalosome (CSN) and is essential for the stability of the complex. The CSN plays a central role in the regulation of E3-cullin RING ubiquitin ligases. [Date last reviewed: 2019-03-07]
FBgn0027055	CSN3	COP9 signalosome subunit 3	COP9 signalosome subunit 3 (CSN3) encodes the subunit 3 of the COP9 signalosome (CSN) and is essential for the stability of the complex. The CSN plays a central role in the regulation of E3-cullin RING ubiquitin ligases. [Date last reviewed: 2019-03-07]
FBgn0027057	CSN1b	COP9 signalosome subunit 1b	COP9 signalosome subunit 1b (CSN1b) encodes the subunit 1 of the COP9 signalosome (CSN) and is essential for the stability of the complex. The CSN plays a central role in the regulation of E3-cullin RING ubiquitin ligases. [Date last reviewed: 2019-03-07]
FBgn0027066	Eb1	Eb1	Eb1 (Eb1) encodes a microtubule end-binding protein that contributes to organization of the microtubule cytoskeleton. It is involved in chromosome segregation, wound healing and flight behavior. [Date last reviewed: 2019-09-26]
FBgn0027079	ValRS	Valyl-tRNA synthetase	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0027080	TyrRS	Tyrosyl-tRNA synthetase	NA
FBgn0027081	ThrRS	Threonyl-tRNA synthetase	NA
FBgn0027082	ProRS-m	Prolyl-tRNA synthetase, mitochondrial	NA
FBgn0027083	MetRS-m	Methionyl-tRNA synthetase, mitochondrial	NA
FBgn0027084	LysRS	Lysyl-tRNA synthetase	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0027085	LeuRS-m	Leucyl-tRNA synthetase, mitochondrial	NA
FBgn0027086	IleRS	Isoleucyl-tRNA synthetase	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0027087	HisRS	Histidyl-tRNA synthetase	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0027088	GlyRS	Glycyl-tRNA synthetase	Glycyl-tRNA synthetase (GlyRS) encodes a protein involved in dendrite morphogenesis and larval lymph gland hemopoiesis. [Date last reviewed: 2019-08-01]
FBgn0027090	GlnRS	Glutaminyl-tRNA synthetase	NA
FBgn0027091	CysRS	Cysteinyl-tRNA synthetase	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0027093	ArgRS	Arginyl-tRNA synthetase	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0027094	AlaRS	Alanyl-tRNA synthetase	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0027095	Manf	Mesencephalic astrocyte-derived neurotrophic factor	Mesencephalic astrocyte-derived neurotrophic factor (Manf) encodes an evolutionarily conserved neurotrophic factor. It contributes to dopamine neuron survival, regulation of unfolded protein response and retinal repair. [Date last reviewed: 2018-09-27]
FBgn0027101	Dyrk3	Dual-specificity tyrosine phosphorylation-regulated kinase 3	NA
FBgn0027108	Inx2	Innexin 2	Innexin 2 (Inx2) encodes a gap junction protein that can form heteromeric gap junction channels via interaction with the products of ogre or Inx3. It can also interact with cell adhesion forming components encoded by shg and arm. It contributes to epithelial organization and polarity of the embryonic epidermis, regulation of morphogen-dependent organ size and stem cell behavior. [Date last reviewed: 2019-03-07]
FBgn0027259	Kmn1	kinetochore Mis12-Ndc80 network component 1	kinetochore Mis12-Ndc80 network component 1 (Kmn1) encodes a protein involved in the movement of chromosomes during mitosis. [Date last reviewed: 2019-09-19]
FBgn0027279	l(1)G0196	lethal (1) G0196	NA
FBgn0027280	l(1)G0193	lethal (1) G0193	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0027287	Gmap	Golgi microtubule-associated protein	Golgi microtubule-associated protein (Gmap) encodes a peripheral Golgi protein that is required for the efficient trafficking within the early secretory pathway, probably by recruiting Rab proteins and effector molecules. [Date last reviewed: 2019-03-07]
FBgn0027291	Idh3a	Isocitrate dehydrogenase 3a	NA
FBgn0027296	temp	tempura	tempura (temp) encodes a protein-prenyltransferase subunit that regulates Notch signaling. [Date last reviewed: 2019-09-19]
FBgn0027329	CCT6	Chaperonin containing TCP1 subunit 6	NA
FBgn0027330	l(1)G0020	lethal (1) G0020	NA
FBgn0027334	l(1)G0004	lethal (1) G0004	NA
FBgn0027335	Rip11	Rab11 interacting protein	Rab11 interacting protein (Rip11) encodes a protein that belongs to Rab11 family interacting proteins (FIP family). It binds only to the GTP bound form of the product of Rab11, thus acting as its effector. It regulates Rhodopsin transport and cytokinesis. [Date last reviewed: 2019-03-21]
FBgn0027338	Kap-alpha3	karyopherin alpha3	karyopherin α3 (Kap-α3) encodes a protein required for the nuclear import of the product of N. [Date last reviewed: 2019-09-12]
FBgn0027339	jim	jim	jim (jim) encodes a zinc finger C2H2 transcription factor involved in dendrite morphogenesis and regulation of chromatin silencing. [Date last reviewed: 2019-07-11]
FBgn0027342	fz4	frizzled 4	NA
FBgn0027348	bgm	bubblegum	NA
FBgn0027356	Amph	Amphiphysin	Amphiphysin (Amph) encodes a BAR and SH3 domain containing protein that regulates muscle transverse tubule formation. It exhibits post-synaptic localization at the neuromuscular junction and its mutants show locomotion defects. [Date last reviewed: 2018-09-27]
FBgn0027359	Tim8	Tim8	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0027363	Stam	Signal transducing adaptor molecule	Signal transducing adaptor molecule (Stam) encodes a component of the ESCRT-0 complex, which mediates multivesicular body formation. It is involved in RTK signaling regulation, tracheal cell migration and endosomal trafficking. [Date last reviewed: 2019-07-11]
FBgn0027375	RecQ5	RecQ5 helicase	RecQ5 helicase (RecQ5) encodes a DNA helicase that maintains genome stability via participation in many nuclear DNA metabolic processes including DNA repair, DNA resolution, and RNA transcription. [Date last reviewed: 2019-03-14]
FBgn0027378	MRG15	MORF-related gene 15	MORF-related gene 15 (MRG15) encodes a protein that contributes to histone acetylation. It is involved in chromatin organization and chromosome separation. [Date last reviewed: 2019-08-01]
FBgn0027453	Dnz1	DNZDHHC/NEW1 zinc finger protein 11	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0027490	D12	D12	D12 (D12) encodes a protein involved in chromatin remodeling and histone acetylation. [Date last reviewed: 2019-06-27]
FBgn0027492	wdb	widerborst	widerborst (wdb) encodes a B' regulatory subunit of the serine/threonine phosphatase complex PP2A. It regulates Hedgehog, protein kinase B and insulin receptor signaling pathways. [Date last reviewed: 2019-09-12]
FBgn0027493	AdSS	Adenylosuccinate Synthetase	Adenylosuccinate Synthetase (AdSS) encodes a protein involved in purine nucleotide biosynthesis and neurogenesis. [Date last reviewed: 2019-03-07]
FBgn0027495	Smyd4-4	SET and MYND domain containing, class 4, member 4	NA
FBgn0027496	epsilonCOP	Coat Protein (coatomer) epsilon	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0027497	Madm	MLF1-adaptor molecule	NA
FBgn0027498	CG2061	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0027499	wde	windei	windei (wde) encodes a chromatin-associated protein that functions as an essential cofactor and binding partner for the methyl transferase encoded by egg. It also binds to the chromosome 4-specific protein encoded by Pof. wde product is required for survival of female germ line cells. [Date last reviewed: 2018-09-27]
FBgn0027500	spd-2	spindle defective 2	"spindle defective 2 (spd-2) encodes a centriole and centrosome protein that is primarily involved in centrosome assembly. Together with the product of cnn, it helps to assemble a ""scaffold"" around the mother centriole that can recruit other centrosomal proteins to the centrosome during mitosis. [Date last reviewed: 2019-03-14]"
FBgn0027503	CG11970	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0027504	CG8878	NA	NA
FBgn0027505	Rab3-GAP	Rab3 GTPase activating protein	NA
FBgn0027506	EDTP	Egg-derived tyrosine phosphatase	NA
FBgn0027507	CG1344	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0027508	Tnks	tankyrase	tankyrase (Tnks) encodes an ADP-ribose polymerase that regulates Wnt signalling by contributing to the degradation of Axn. [Date last reviewed: 2019-09-12]
FBgn0027509	TBCD	tubulin folding cofactor D	tubulin folding cofactor D (TBCD) encodes one of the tubulin folding cofactors, which assist in the formation of tubulin heterodimers. It cooperates with the product of Dscam1 to regulate microtubule organization during neural development. [Date last reviewed: 2019-03-14]
FBgn0027512	CG10254	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0027513	ana2	anastral spindle 2	"anastral spindle 2 (ana2) encodes a centriole protein that is essential for centriole assembly, promoting the assembly of the central ""cartwheel"" structure. It may also have an independent role in promoting asymmetric divisions in larval neuroblasts. [Date last reviewed: 2019-03-07]"
FBgn0027514	CG1024	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0027515	CG7115	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0027518	Wdr24	WD repeat domain 24	WD repeat domain 24 (Wdr24) encodes a component of the GATOR2 complex that promotes activation of the Crtc product and anabolic metabolism. It localizes to lysosomes and autolysosomes and regulates lysosome function independent of the activity of the Crtc product. [Date last reviewed: 2019-03-21]
FBgn0027524	CG3909	NA	NA
FBgn0027525	LTV1	LTV1 ribosome biogenesis factor	LTV1 ribosome biogenesis factor (LTV1) encodes a protein involved in pre-rRNA processing that is required for the proper biogenesis of the 40S ribosome. LTV1 product is a direct transcriptional target of Myc, thus it is critical for cell growth and survival. [Date last reviewed: 2018-09-27]
FBgn0027526	Ublcp1	Ubiquitin-like domain-containing C-terminal domain phosphatase 1	Ubiquitin-like domain-containing C-terminal domain phosphatase 1 (Ublcp1) encodes a nuclear HAD family phospho-Ser/Thr phosphatase that binds and dephosphorylates the nuclear 26S proteasome and inhibits proteasome activity. [Date last reviewed: 2019-03-14]
FBgn0027529	tapas	tapas	NA
FBgn0027532	CG7139	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0027535	botv	brother of tout-velu	NA
FBgn0027537	Nup93-1	Nucleoporin 93kD-1	Nucleoporin 93kD-1 (Nup93-1) encodes a protein that directly interacts with the product of Nup154. However, the product of Nup93-1 is not necessary for the Nup154-dependent organization of the inner nuclear membrane proteins at the nuclear envelope. [Date last reviewed: 2019-03-14]
FBgn0027538	beta4GalNAcTA	beta1,4-N-acetylgalactosaminyltransferase A	β1,4-N-acetylgalactosaminyltransferase A (β4GalNAcTA) encodes a acetylgalactosaminyltransferase involved in glycolipid biosynthesis. It contributes to the development of the neuromuscular junction. [Date last reviewed: 2019-09-12]
FBgn0027539	lili	lilipod	lilipod (lili) encodes a multi-pass transmembrane protein required for Dpp signal transduction in the female germline to promote ovarian stem cell maintenance. [Date last reviewed: 2018-09-27]
FBgn0027547	CG1927	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0027548	nito	spenito	NA
FBgn0027549	Nulp1	Nuclear localized protein 1	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0027550	CG6495	NA	NA
FBgn0027552	CG10863	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0027553	NELF-B	NELF-B	NA
FBgn0027554	CG8042	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0027556	CG4928	NA	NA
FBgn0027558	Pgant3	Polypeptide N-Acetylgalactosaminyltransferase 3	Polypeptide N-Acetylgalactosaminyltransferase 3 (Pgant3) encodes a member of the UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase family. It catalyzes the transfer of a GalNAc sugar onto the hydroxyl groups of serine and threonine in secreted or membrane-bound proteins. Pgant3 product modulates secretion of extracellular matrix proteins and influences integrin-mediated cell adhesion during development. [Date last reviewed: 2018-09-27]
FBgn0027561	CG18659	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0027564	CG3149	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0027565	CG5498	NA	NA
FBgn0027567	Ciz1	Ciz1 zinc finger protein	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0027568	Cand1	Cullin-associated and neddylation-dissociated 1	NA
FBgn0027569	cert	ceramide transfer protein	ceramide transfer protein (cert) encodes a protein involved in determination of lifespan. Mutant flies present accelerated aging due to oxidative stress. [Date last reviewed: 2018-09-27]
FBgn0027572	ACOX1	acyl-CoA oxidase 1	NA
FBgn0027574	CG5815	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0027578	Nepl21	Neprilysin-like 21	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0027579	mino	minotaur	minotaur (mino) encodes a member of the conserved glycerol-3-phosphate O-acyltransferase family, which converts glycerol-3-phosphate into lysophosphatidic acid. It functions in phosphatidic acid biosynthesis. It is also essential for piRNA biogenesis in gonads, with mino mutants showing transposon de-repression and sterility phenotypes. [Date last reviewed: 2019-03-14]
FBgn0027580	PCB	Pyruvate carboxylase	Pyruvate carboxylase (PCB) encodes an enzyme that regulates D-serine levels. [Date last reviewed: 2019-09-12]
FBgn0027581	CG6191	NA	NA
FBgn0027582	CG6230	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0027583	CG7601	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0027585	CG8740	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0027587	Prp4k	Pre-mRNA processing factor 4 kinase	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0027588	GCS2alpha	Glucosidase 2 alpha subunit	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0027590	GstE12	Glutathione S transferase E12	Glutathione S transferase E12 (GstE12) encodes an enzyme involved in glutathione metabolism. [Date last reviewed: 2018-09-27]
FBgn0027592	MED15	Mediator complex subunit 15	Mediator complex subunit 15 (MED15) encodes a subunit of the mediator complex required for regulating RNA polymerase II transcripts. Mediator complex subunits function as Notch signaling modulators. [Date last reviewed: 2019-03-14]
FBgn0027594	drpr	draper	draper (drpr) encodes a single-pass transmembrane receptor that is involved in phagocytosis by glia, macrophages, and epithelia. It signals downstream through the proteins encoded by Src42A and Shark to promote Rac1 function and transcriptional changes through the products of Jra and Stat92E. It is also required for activation of autophagy in salivary glands. [Date last reviewed: 2019-03-21]
FBgn0027596	Kank	Kank	Kank (Kank) encodes a microtubule plus-end binding protein. [Date last reviewed: 2019-09-12]
FBgn0027597	CG17712	NA	NA
FBgn0027598	cindr	CIN85 and CD2AP related	CIN85 and CD2AP related (cindr) encodes an adaptor protein that links cell surface junctions and adhesion proteins with multiple components of the actin cytoskeleton. It regulates cytoskeletal dynamics, eye patterning and endocytosis. It also cooperates with the product of scra to promote intercellular bridge stability during cytokinesis. [Date last reviewed: 2019-03-07]
FBgn0027599	CG2790	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0027601	pdgy	pudgy	pudgy (pdgy) encodes an acyl-CoA synthetase that activates fatty acids by conjugating them to CoA. It is a FOXO transcriptional target that preferentially activates fatty acids destined for beta-oxidation. [Date last reviewed: 2019-03-14]
FBgn0027602	CG8611	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0027603	Ulp1	Ulp1	Ulp1 (Ulp1) encodes a cysteine protease that catalyzes both SUMO maturation and SUMO deconjugation. It localizes to the nucleoplasmic face of the nuclear pore complex. Ulp1 knockdown in S2 cells results in relocalization of SUMO from the nucleus to the cytoplasm. [Date last reviewed: 2019-03-21]
FBgn0027607	CG8230	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0027609	morgue	modifier of rpr and grim, ubiquitously expressed	modifier of rpr and grim, ubiquitously expressed (morgue) encodes an F box/ubiquitin conjugase domain protein. It regulates cell death by controlling the levels of the apoptosis inhibitor encoded by Diap1. [Date last reviewed: 2019-07-11]
FBgn0027610	Dic1	Dicarboxylate carrier 1	Dicarboxylate carrier 1 (Dic1) encodes a protein of the inner mitochondrial membrane that catalyzes an electroneutral exchange across the inner mitochondrial membrane of dicarboxylates (e.g. malonate, malate, succinate) for inorganic phosphate and certain sulfur-containing compounds (e.g. sulfite, sulfate, thiosulfate). The main role of the product of is in gluconeogenesis. The carrier protein has also an anaplerotic role supplying substrates for the Krebs cycle. [Date last reviewed: 2019-03-07]
FBgn0027611	LManII	Lysosomal alpha-mannosidase II	Lysosomal α-mannosidase II (LManII) encodes a mannosyl-oligosaccharide 1,2-alpha-mannosidase involved in the degradation of asparagine-linked carbohydrates of glycoproteins. [Date last reviewed: 2019-09-12]
FBgn0027615	OXA1L	OXA1L mitochondrial inner membrane protein	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0027616	Ythdc1	YTH domain containing 1	YTH domain containing 1 (Ythdc1) encodes a pre-mRNA binding protein involved in the regulation of mRNA alternative splicing and sex determination. [Date last reviewed: 2019-09-19]
FBgn0027617	CG5808	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0027619	eIF3j	eukaryotic translation initiation factor 3 subunit j	NA
FBgn0027620	Acf	ATP-dependent chromatin assembly factor large subunit	ATP-dependent chromatin assembly factor large subunit (Acf) encodes a common subunit of two ATP-dependent nucleosome remodeling complexes: the ATP-dependent chromatin assembly and remodeling factor (ACF) and the chromatin accessibility omplex. In these complexes the product of Acf interacts with the ATPase encoded by Iswi and modulates its nucleosome sliding activity, which affects the regularity of nucleosomal arrays and their precise spacing. The ACF complex has also been found to promote nucleosome assembly. [Date last reviewed: 2019-03-21]
FBgn0027621	Pfrx	6-phosphofructo-2-kinase	NA
FBgn0027655	htt	huntingtin	huntingtin (htt) encodes a scaffold protein involved in mitotic spindle orientation, chromatin regulation and axonal transport. It is the ortholog of human HTT and has been manipulated to study Huntington's disease in flies. [Date last reviewed: 2019-06-13]
FBgn0027657	glob1	globin 1	globin 1 (glob1) encodes a peroxidase involved in the response to oxidative stress and the maintenance of F-actin based cytoskeleton. [Date last reviewed: 2019-09-12]
FBgn0027660	blot	bloated tubules	bloated tubules (blot) encodes a member of the sodium- and chloride-dependent neurotransmitter symporter family. It is required for cortical actin organisation and contributes to embryonic cellularization and renal tubule development in larvae. [Date last reviewed: 2019-03-07]
FBgn0027779	VhaSFD	Vacuolar H[+]-ATPase SFD subunit	NA
FBgn0027780	Aasdh	Aminoadipate-semialdehyde dehydrogenase	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0027783	SMC2	Structural maintenance of chromosomes 2	Structural maintenance of chromosomes 2 (SMC2) encodes a condensin subunit involved in chromosome condensation and cell division. It contributes to neurogenesis and stem cell differentiation. [Date last reviewed: 2019-03-14]
FBgn0027784	Prp18	Prp18	NA
FBgn0027785	NP15.6	NP15.6	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0027786	Mtch	Mitochondrial carrier homolog 1	NA
FBgn0027791	O-fut2	O-fucosyltransferase 2	NA
FBgn0027794	Lrpprc2	Leucine-rich pentatricopeptide repeat containing 2	Leucine-rich pentatricopeptide repeat containing 2 (Lrpprc2) encodes an RNA-binding protein that forms a complex with the product of SLIRP2. It localizes to the mitochondrial matrix where it functions to coordinate mitochondrial translation. [Date last reviewed: 2019-03-14]
FBgn0027795	CG14785	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-10-13]
FBgn0027835	Dp1	Dodeca-satellite-binding protein 1	Dodeca-satellite-binding protein 1 (Dp1) encodes a single-stranded nucleic acid binding protein that belongs to the vigilin protein family. It binds to target mRNAs and enhances their translation. [Date last reviewed: 2018-09-27]
FBgn0027836	Dgp-1	Dgp-1	NA
FBgn0027841	CstF64	Cleavage stimulation factor 64 kD subunit	Cleavage stimulation factor 64 kD subunit (CstF64) encodes an RNA-binding protein that is part of the cleavage stimulation factor (CstF) complex. As part of the CstF complex, it interacts with the polyadenylation protein encoded bysu(f). The product of CstF64 is necessary for the cleavage and polyadenylation of most mRNAs and for 3' end processing of mRNAs that encode the replication-dependent histones. [Date last reviewed: 2018-09-27]
FBgn0027843	CAH2	Carbonic anhydrase 2	Carbonic anhydrase 2 (CAH2) encodes an alpha-class carbonate dehydratase that catalyzes the reversible hydration/dehydration of carbon dioxide to bicarbonate and protons. [Date last reviewed: 2019-09-12]
FBgn0027864	Ogg1	8-oxoguanine DNA glycosylase	8-oxoguanine DNA glycosylase (Ogg1) encodes the DNA glycosylase required for removal of 8-oxo guanines from nuclei. Depletion of Ogg1 resulted in accumulation of the oxidized guanines in nuclei of adult intestines, treated with an oxidative stress inducer. Conversely, its overexpression conferred the resistance to oxidative stress and a significantly longer lifespan. [Date last reviewed: 2018-09-27]
FBgn0027865	Tsp96F	Tetraspanin 96F	NA
FBgn0027866	CG9776	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0027868	Nup107	Nucleoporin 107kD	NA
FBgn0027872	rdgBbeta	rdgBbeta	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0027873	Cpsf100	Cleavage and polyadenylation specificity factor 100	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0027889	ball	ballchen	ballchen (ball) encodes a nuclear serine/threonine kinase that regulates chromatin organization through phosphorylation of the product of baf. It contributes to stem cell maintenance in various tissues, as well as chromosome condensation and segregation in meiosis. [Date last reviewed: 2019-03-07]
FBgn0027903	PolD2	DNA polymerase delta subunit 2	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0027929	NimB1	Nimrod B1	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0027930	MP1	Melanization Protease 1	Melanization Protease 1 (MP1) encodes a serine protease which plays an essential role in the melanization immune response, by acting downstream of Sp7 to activate PPO1. It may function in diverse Hayan-dependent PPO1-activating cascades that are negatively controlled by different serpin proteins: Spn27A in the hemolymph and Spn77Ba in the trachea. [Date last reviewed: 2020-01-16]
FBgn0027932	Akap200	A kinase anchor protein 200	A kinase anchor protein 200 (Akap200) encodes a scaffolding protein that contributes to the spatial and temporal regulation of the Protein Kinase A holoenzyme. It regulates the Notch signaling and the organization of the actin cytoskeleton. [Date last reviewed: 2019-09-12]
FBgn0027945	ppl	pumpless	NA
FBgn0027948	msps	mini spindles	NA
FBgn0027949	msb1l	msb1l	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0027950	MBD-like	Methyl-CpG binding domain protein-like	Methyl-CpG binding domain protein-like (MBD-like) encodes a protein involved in chromosome condensation and transcription repression. [Date last reviewed: 2019-08-01]
FBgn0027951	MTA1-like	Metastasis associated 1-like	NA
FBgn0028292	ric8a	ric8a	ric8a (ric8a) encodes a guanine nucleotide-exchange factor for the product of Gαi. Its function is necessary to ensure cortical localization of the heterotrimeric subunits encoded by Gαi and Gβ13F, thereby regulating spindle orientation during asymmetric cell division in the sensory lineage. [Date last reviewed: 2019-03-14]
FBgn0028325	Pdha	Pyruvate dehydrogenase E1 alpha subunit	NA
FBgn0028327	l(1)G0320	lethal (1) G0320	NA
FBgn0028331	l(1)G0289	lethal (1) G0289	NA
FBgn0028341	Ptpmeg2	Protein tyrosine phosphatase Meg2	Protein tyrosine phosphatase Meg2 (Ptpmeg2) encodes a phosphatase involved in border follicle cell migration. [Date last reviewed: 2019-08-01]
FBgn0028342	ATPsyndelta	ATP synthase, delta subunit	NA
FBgn0028343	Ankle2	Ankle2	Ankle2 (Ankle2) encodes an important protein for proper development of the third instar larval CNS. Ankle2 loss causes a small brain phenotype, defects in proliferation and excessive apoptosis. [Date last reviewed: 2019-03-07]
FBgn0028360	Cdc7	Cdc7 kinase	Cdc7 kinase (Cdc7) encodes a conserved protein kinase that is activated by the regulatory subunit encoded by chif during late G1/S of the cell cycle. The activated product of Cdc7 promotes the initiation of DNA replication through phosphorylation, and thereby activation, of the DNA helicase encoded by Mcm2 . [Date last reviewed: 2019-03-07]
FBgn0028372	isopeptidase-T-3	isopeptidase-T-3	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0028375	heix	heixuedian	heixuedian (heix) encodes a protein belonging to the UbiA prenyltransferase family that participates in the regulation of cholesterol. It is involved in signal transduction pathways such as JAK/STAT, Ras/MAPK, Toll, IMD, and Notch. It contributes to growth regulation, cell differentiation and apoptosis, antioxidation and neurodegeneration. [Date last reviewed: 2019-03-07]
FBgn0028380	fal	falten	falten (fal) encodes a protein with potential GTPase activity. It is expressed in the mesoderm and is elevated in embryos lacking how function. [Date last reviewed: 2019-03-07]
FBgn0028382	cyp33	cyclophilin-33	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0028387	chm	chameau	chameau (chm) encodes a histone acetyl transferase involved in epigenetic mechanisms of transcriptional control and regulation of replication origin activity. Its functions include modulation of JNK activity and gene regulation by Polycomb group genes. [Date last reviewed: 2019-03-07]
FBgn0028394	CG17834	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0028397	Tob	Transducer of ERBB2	Tob (Tob) encodes a protein involved in long-term memory. [Date last reviewed: 2019-09-19]
FBgn0028398	Taf10	TBP-associated factor 10	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0028399	Serinc	Serine incorporator	TMS1 (TMS1) encodes a putative L-serine transmembrane transporter. [Date last reviewed: 2019-03-14]
FBgn0028402	Polr3E	RNA polymerase III subunit E	NA
FBgn0028406	Drep4	DNA fragmentation factor-related protein 4	DNA fragmentation factor-related protein 4 (Drep4) encodes a CIDE domain containing protein that can interact with the proteins encoded by Drep3 and Drep1 via CIDE-CIDE interaction. It is the ortholog of human DFFB, which has a nuclease activity. The Drep4 product might function in apoptotic DNA fragmentation. [Date last reviewed: 2018-10-11]
FBgn0028408	Drep2	DNA fragmentation factor-related protein 2	DNA fragmentation factor-related protein 2 (Drep2) encodes a protein involved in neuron death regulation. [Date last reviewed: 2019-09-12]
FBgn0028411	Nxt1	NTF2-related export protein 1	NA
FBgn0028421	Kap3	Kinesin associated protein 3	Kinesin associated protein 3 (Kap3) encodes the non-motor accessory subunit of the heterotrimeric kinesin-2. It associates to the coiled-coil stalk domain of the products of Klp68D andKlp64D. It plays an essential role in sensory cilia assembly and axonal transport. [Date last reviewed: 2019-03-14]
FBgn0028425	JhI-21	Juvenile hormone Inducible-21	NA
FBgn0028426	RNaseZ	Ribonuclease Z	Ribonuclease Z (RNaseZ) is a highly conserved gene that encodes the endoribonuclease RNase Z, which cleaves pre-tRNA molecules directly 3' to the discriminator. It has at least two biological roles - nuclear pre-tRNA processing and mitochondrial primary transcript processing. [Date last reviewed: 2019-03-14]
FBgn0028427	Ilk	Integrin linked kinase	Integrin linked kinase (Ilk) encodes a pseudokinase that, together with the products of stck and parvin, mediates part of the adhesive functions of integrins. [Date last reviewed: 2019-03-07]
FBgn0028429	I-2	Inhibitor-2	Inhibitor-2 (I-2) encodes a protein phosphatase 1 inhibitor. [Date last reviewed: 2019-09-12]
FBgn0028430	He	Hemese	NA
FBgn0028434	Ercc1	Ercc1	Ercc1 (Ercc1) encodes the non-catalytic partner of the nuclease encoded by mei-9 that cuts structures formed during DNA repair. The mei-9-Ercc1 heterodimer interacts with the product of mus312 to make meiotic crossovers. The functions of the product of Ercc1 include repair of UV-induced DNA damage, repair of base adducts, a backup pathway for mismatch repair and meiotic recombination. [Date last reviewed: 2019-03-07]
FBgn0028436	ECSIT	ECSIT	NA
FBgn0028467	Ube4A	Ubiquitination factor E4A	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0028468	rtet	tetracycline resistance	NA
FBgn0028471	Nab2	Nuclear polyadenosine RNA-binding 2	Nuclear polyadenosine RNA-binding 2 (Nab2) encodes a zinc-finger polyadenosine RNA binding protein that is expressed widely in many cell types but required specifically within the developing nervous system for proper behavior and axonogenesis. The product of Nab2 in supports in neurons short term memory and development of the brain mushroom bodies. [Date last reviewed: 2019-03-14]
FBgn0028473	Non1	Novel nucleolar protein 1	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0028474	CG4119	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0028475	Hrd3	HMG-coA reductase degradation 3	NA
FBgn0028476	Usp1	Ubiquitin specific protease 1	NA
FBgn0028479	Mtpalpha	Mitochondrial trifunctional protein alpha subunit	Mitochondrial trifunctional protein α subunit (Mtpα) encodes a subunit of the mitochondrial trifunctional protein. It possesses 3-enoyl-CoA hydratase and 3-hydroxyacyl-CoA dehydrogenase activities, which catalyze the second and third steps,respectively, of the β-oxidation of long-chain fatty acids. [Date last reviewed: 2019-09-12]
FBgn0028480	CG17841	NA	NA
FBgn0028482	bdl	borderless	borderless (bdl) encodes a cell adhesion molecule that is required for glial extension and axon ensheathment. Its down-regulation by the products of tutl and Lar is required for photoreceptor axonal tiling and layer-specific target selection. [Date last reviewed: 2019-03-07]
FBgn0028484	Ack	Activated Cdc42 kinase	NA
FBgn0028487	f-cup	flyers-cup	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0028490	CG31705	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-10-13]
FBgn0028491	CG2930	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0028494	CG6424	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0028497	Mtmr6	Myotubularin related protein 6	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0028499	CG7985	NA	NA
FBgn0028500	Rich	RIC1 homolog	NA
FBgn0028504	CG12182	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-10-13]
FBgn0028506	CG4455	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0028507	CG3793	NA	NA
FBgn0028509	CenG1A	Centaurin gamma 1A	Centaurin gamma 1A (CenG1A) encodes a GTPase that may have a role in regulating the second to third instar larval transition, which is ecdysone signaling-dependent. [Date last reviewed: 2019-03-07]
FBgn0028513	CG9254	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0028514	CG4793	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0028515	EndoGI	Endonuclease G inhibitor	Endonuclease G inhibitor (EndoGI) encodes an inhibitor of the enzyme encoded by EndoG by tight binding to the enzymatic active site. Since the product of EndoG is mostly or entirely localized in mitochondria, the product of EndoGI has been suggested to protect cells against mis-localization of the enzyme. [Date last reviewed: 2019-03-07]
FBgn0028523	CG5888	NA	NA
FBgn0028530	mTTF	mitochondrial transcription termination factor	mitochondrial transcription termination factor (mTTF) encodes a sequence-specific DNA binding protein that interacts with two regions of the mitochondrial genome, each located at the common 3' end of oppositely transcribed gene clusters. The mTTF product arrests transcription in the 'forward' direction, as well as acting as a replication fork barrier, which is believed to prevent collisions between the replication and transcription machineries. Its dimerization partner, encoded by mTerf5, antagonizes these activities. [Date last reviewed: 2018-10-11]
FBgn0028538	Sec71	Secretory 71	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0028539	Eato	Engulfment ABC Transporter in the ovary	NA
FBgn0028540	CG9008	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0028541	TM9SF4	Transmembrane 9 superfamily protein member 4	Transmembrane 9 superfamily protein member 4 (TM9SF4) encodes a nonaspanin-type protein involved in cellular immunity. [Date last reviewed: 2019-09-12]
FBgn0028542	NimB4	Nimrod B4	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0028543	NimB2	Nimrod B2	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0028546	ics	icarus	icarus (ics) encodes RSU1 (Ras suppressor 1), an adapter protein that participates in integrin-dependent processes by interacting with the integrin effector protein encoded by stck. [Date last reviewed: 2019-03-07]
FBgn0028550	Atf3	Activating transcription factor 3	Activating transcription factor 3 (Atf3) encodes a transcription factor whose levels are tightly controlled during development. It forms homodimers or heterodimerizes with the product of Jra. It contributes to abdominal morphogenesis, and immune system and metabolic homeostasis. [Date last reviewed: 2019-03-07]
FBgn0028552	gammaSnap1	gamma Soluble NSF attachment protein 1	γ Soluble NSF attachment protein 1 (γSnap1) encodes a protein involved in the dorsal/ventral pattern formation of the wing disc. [Date last reviewed: 2019-07-11]
FBgn0028554	x16	x16 splicing factor	x16 splicing factor (x16) encodes a protein involved in RNA splicing and RNA metabolism regulation. [Date last reviewed: 2019-09-19]
FBgn0028563	sut1	sugar transporter 1	NA
FBgn0028572	qtc	quick-to-court	quick-to-court (qtc) encodes an alpha-helical coiled-coiled protein whose mutants exhibit altered male courtship behavior. [Date last reviewed: 2019-03-14]
FBgn0028573	prc	pericardin	pericardin (prc) encodes a type IV collagen-like extracellular matrix protein involved in heart development. [Date last reviewed: 2019-03-14]
FBgn0028577	hfp	half pint	half pint (hfp) encodes a single stranded nucleic acid binding protein with roles in transcription and RNA splicing. It functions in Myc transcriptional repression and cell growth control, via interaction with the transcription factor encoded by hay. [Date last reviewed: 2019-03-07]
FBgn0028579	phtf	phtf	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0028582	lqf	liquid facets	liquid facets (lqf) encodes an epsin, which is an endocytic adaptor that contributes to endocytic network stability/regulation and membrane bending. It contributes to endocytosis and regulates the BMP and Notch signaling pathways. [Date last reviewed: 2019-09-12]
FBgn0028646	aralar1	aralar1	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0028647	CG11902	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0028648	mRpL50	mitochondrial ribosomal protein L50	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0028662	VhaPPA1-1	Vacuolar H[+] ATPase PPA1 subunit 1	Vacuolar H[+] ATPase PPA1 subunit 1 (VhaPPA1-1) encodes a protein involved in tracheal terminal branching. [Date last reviewed: 2019-09-26]
FBgn0028663	VhaM9.7-b	Vacuolar H[+] ATPase M9.7 subunit b	NA
FBgn0028664	VhaM9.7-c	Vacuolar H[+] ATPase M9.7 subunit c	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0028670	Vha100-2	Vacuolar H[+] ATPase 100kD subunit 2	NA
FBgn0028671	Vha100-1	Vacuolar H[+] ATPase 100kD subunit 1	Vacuolar H[+] ATPase 100kD subunit 1 (Vha100-1) encodes a subunit of the V0 domain of V-ATPase, which acidifies autophagosomes and lysosomes in neurons. The product of Vha100-1 is involved in autophagosome maturation, tracheal branching and eye development. [Date last reviewed: 2019-09-26]
FBgn0028675	Sur	Sulfonylurea receptor	Sulfonylurea receptor (Sur) encodes a predicted ATP-sensitive K[+] channel expressed almost exclusively in the embryonic heart. Sur loss in the adult heart causes increased oxidative stress and pacing-induced heart failure. [Date last reviewed: 2019-03-14]
FBgn0028683	spt4	spt4	NA
FBgn0028684	Rpt5	Regulatory particle triple-A ATPase 5	Regulatory particle triple-A ATPase 5 (Rpt5) encodes a component of the 26S proteasome, which degrades polyubiquitinated proteins in the cytoplasm and nucleus. [Date last reviewed: 2019-08-01]
FBgn0028685	Rpt4	Regulatory particle triple-A ATPase 4	Regulatory particle triple-A ATPase 4 (Rpt4) encodes the 19S proteasomal ATPase, which is a component of the 26S proteosome complex. It localizes to the nucleolus and participates in regulating rRNA transcription. It physically interacts with the tumor suppressor encoded by BHD. [Date last reviewed: 2019-03-14]
FBgn0028686	Rpt3	Regulatory particle triple-A ATPase 3	NA
FBgn0028687	Rpt1	Regulatory particle triple-A ATPase 1	Regulatory particle triple-A ATPase 1 (Rpt1) encodes an AAA-type ATPase protein that forms part of the heterohexameric ATPase ring of the regulatory complex of the 26S proteasome. [Date last reviewed: 2019-03-14]
FBgn0028688	Rpn7	Regulatory particle non-ATPase 7	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0028689	Rpn6	Regulatory particle non-ATPase 6	Regulatory particle non-ATPase 6 (Rpn6) encodes a structural subunit of the 26S proteasome, located in the lid section of the 19S regulatory particle. In the 26S proteasome, it forms a bridge between the 19S regulatory and 20S core particles. [Date last reviewed: 2018-10-11]
FBgn0028690	Rpn5	Regulatory particle non-ATPase 5	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0028691	Rpn9	Regulatory particle non-ATPase 9	NA
FBgn0028692	Rpn2	Regulatory particle non-ATPase 2	NA
FBgn0028693	Rpn12	Regulatory particle non-ATPase 12	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0028694	Rpn11	Regulatory particle non-ATPase 11	NA
FBgn0028695	Rpn1	Regulatory particle non-ATPase 1	Regulatory particle non-ATPase 1 (Rpn1) encodes a component of the 26S proteasome, which degrades polyubiquitinated proteins in the cytoplasm and nucleus. [Date last reviewed: 2019-08-01]
FBgn0028697	RpL15	Ribosomal protein L15	NA
FBgn0028700	RfC38	Replication factor C 38kD subunit	NA
FBgn0028703	Nhe3	Na[+]/H[+] hydrogen exchanger 3	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0028704	Nckx30C	Nckx30C	NA
FBgn0028707	Mt2	Methyltransferase 2	Methyltransferase 2 (Mt2) encodes a (cytosine-5) tRNA methyltransferase. The modification protects tRNAs against endonucleolytic cleavage and contributes to stress resistance, protein translation and small RNA-mediated gene regulation. [Date last reviewed: 2019-03-14]
FBgn0028708	Mst85C	Mst85C	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0028717	Lnk	Lnk	Lnk (Lnk) encodes a member of the SH2B family of adaptor proteins. It functions within the insulin signalling pathway as an intracellular adaptor for the insulin receptor. It stabilises the interaction between the activated insulin receptor and the insulin receptor substrate, which are encoded by InR and chico respectively. [Date last reviewed: 2018-10-11]
FBgn0028734	Fmr1	Fmr1	Fmr1 (Fmr1) encodes an RNA and channel binding protein. It acts as a neural growth brake regulating RNA trafficking, RNA translation and neuronal excitability. Fmr1 loss causes Fragile X syndrome. [Date last reviewed: 2019-03-07]
FBgn0028737	eEF1beta	eukaryotic translation elongation factor 1 beta	NA
FBgn0028740	CG6362	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-10-13]
FBgn0028744	CG5033	NA	NA
FBgn0028746	CG18508	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0028833	Cmpk	Cytidine/uridine monophosphate kinase 1	Dak1 (Dak1) encodes a mitochondrial pyrimidine nucleoside monophosphate kinase with cytidylate kinase and uridylate kinase activity. [Date last reviewed: 2019-09-19]
FBgn0028836	CSN7	COP9 signalosome subunit 7	COP9 signalosome subunit 7 (CSN7) encodes the subunit 7 of the COP9 signalosome (CSN) and is essential for the stability of the complex. The CSN plays a central role in the regulation of E3-cullin RING ubiquitin ligases. [Date last reviewed: 2019-03-07]
FBgn0028837	CSN6	COP9 signalosome subunit 6	COP9 signalosome subunit 6 (CSN6) encodes the subunit 6 of the COP9 signalosome (CSN). The CSN plays a central role in the regulation of E3-cullin RING ubiquitin ligases. [Date last reviewed: 2019-03-07]
FBgn0028863	stol	stolid	NA
FBgn0028886	CG15279	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0028894	GMF	Glia maturation factor	Glia maturation factor (GMF) encodes a protein belonging to the ADF-H domain family of proteins, which promote dissambly of actin networks. It specifically binds to and promotes disassembly of Arp2/3-nucleated lamellipodial actin networks. It plays a role in promoting protrusion dynamics during cell migration. [Date last reviewed: 2019-03-07]
FBgn0028895	CG17328	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0028897	CG4935	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0028916	CG33090	NA	NA
FBgn0028919	CG16865	NA	NA
FBgn0028926	NC2beta	Negative Cofactor 2beta	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0028931	CG16863	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0028932	CG16890	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0028936	NimB5	Nimrod B5	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0028940	Cyp28a5	Cytochrome P450 28a5	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0028952	Kebab	Kinetochore and EB1 associated basic protein	NA
FBgn0028953	CG14478	NA	NA
FBgn0028955	CG8788	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0028956	mthl3	methuselah-like 3	NA
FBgn0028962	AlaRS-m	Alanyl-tRNA synthetase, mitochondrial	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0028965	CG9933	NA	NA
FBgn0028968	gammaCOP	Coat Protein (coatomer) gamma	Coat Protein (coatomer) γ (γCOP) encodes a subunit of the coat complex of COPI vesicles, which transport cargo within the Golgi apparatus and from the Golgi apparatus to the endoplasmic reticulum. Its functions include membrane and protein trafficking in the secretory apparatus. [Date last reviewed: 2019-09-26]
FBgn0028969	deltaCOP	Coat Protein (coatomer) delta	Coat Protein (coatomer) δ (δCOP) mutants show narrow tracheal tubes due to defective luminal extracellular matrix secretion. [Date last reviewed: 2019-09-26]
FBgn0028970	RabGGTb	Rab geranylgeranyltransferase subunit beta	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0028978	trbl	tribbles	tribbles (trbl) encodes the founding member of the Trib family of kinase-like proteins. It contributes to cell growth, cell migration and metabolism. [Date last reviewed: 2019-03-14]
FBgn0028979	tio	tiptop	tiptop (tio) encodes a DNA binding protein involved in the formation of embryonic thoracic segments, Malpighian tubules, and eye development. [Date last reviewed: 2019-03-14]
FBgn0028980	tant	tantalus	tantalus (tant) encodes a DNA binding protein. It binds to polytene chromosome sites that overlap with the product of Asx. [Date last reviewed: 2019-03-21]
FBgn0028982	Spt6	Spt6	NA
FBgn0028983	Spn55B	Serpin 55B	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0028984	Spn88Ea	Serpin 88Ea	NA
FBgn0028990	Spn27A	Serpin 27A	Serpin 27A (Spn27A) encodes a hemolymphatic serpin that negatively regulates a serine protease involved in the melanization cascade. It also inhibits the serine protease encoded by ea in dorsoventral patterning of the early embryo. [Date last reviewed: 2019-03-14]
FBgn0028991	seq	sequoia	sequoia (seq) encodes a pan-neuronally expressed zinc-finger transcription factor that governs dendrite and axon outgrowth. It is necessary for the proper development of tracheal branches and dendritic branches of multidendritic neurons, as well as development of the R8 cell in eye development. [Date last reviewed: 2019-03-14]
FBgn0028992	sds22	sds22	NA
FBgn0028996	onecut	onecut	onecut (onecut) encodes a transcription factor that binds two different DNA motifs (Cut and Hox). It is mainly expressed in mature neurons and maintains neuronal identity. [Date last reviewed: 2019-03-14]
FBgn0028997	nmdyn-D7	nmdyn-D7	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0029002	miple2	midkine and pleiotrophin 2	midkine and pleiotrophin 2 (miple2) encodes a small secreted protein that binds Heparin and is closely related at the amino acid sequence to the product of miple1. It is strongly expressed in the developing endoderm. [Date last reviewed: 2019-03-14]
FBgn0029006	Smurf	SMAD specific E3 ubiquitin protein ligase	NA
FBgn0029067	Dd	Dullard	Dullard (Dd) encodes a putative protein phosphatase of the Haloacid Dehalogenase family. It has a negative effect on BMP signaling-dependent wing vein formation. [Date last reviewed: 2019-03-07]
FBgn0029079	icln	icln	icln (icln) encodes a cytosolic protein that functions as an assembly chaperone in the biogenesis of pre-mRNA processing small nuclear ribonucleoproteins (snRNPs) via interaction with Sm proteins. It is required in the motor system for viability and motor behaviour. [Date last reviewed: 2019-03-07]
FBgn0029088	disp	dispatched	dispatched (disp) encodes a multipass transmembrane protein and a member of the RND transporter family. It is required for the release and long-range activity of the lipid-modified product of hh from producing cells. The products of hh and disp control cell growth, survival, fate, and patterning. [Date last reviewed: 2019-03-07]
FBgn0029092	ced-6	ced-6	ced-6 (ced-6) encodes an intracellular adaptor protein involved in signal transduction. It binds the engulfment receptor encoded by drpr and transmits a signal for the induction of the phagocytosis of apoptotic cells. [Date last reviewed: 2019-03-07]
FBgn0029093	cathD	cathepsin D	cathD (cathD) encodes a protein involved in apoptosis and the defense response to Gram-negative bacteria. [Date last reviewed: 2019-09-19]
FBgn0029094	asf1	anti-silencing factor 1	NA
FBgn0029095	aru	arouser	arouser (aru) encodes an SH3 adaptor protein that interacts with Egfr and PI3K pathways. Its roles include regulation of synapse number, memory formation and ethanol sedation sensitivity. [Date last reviewed: 2019-03-07]
FBgn0029113	Uba2	Ubiquitin-like activating enzyme 2	Ubiquitin-like activating enzyme 2 (Uba2) encodes one of two subunits (along with the product of Aos1) of the heterodimeric SUMO activating enzyme. It contains the catalytic cysteine residue that first becomes adenylated using ATP and that then forms a thioester linkage to the C-terminal end of SUMO. [Date last reviewed: 2019-09-26]
FBgn0029114	Tollo	Tollo	Tollo (Tollo) encodes a member of the Toll-like receptor family. It contributes to the innate immune response, regulation of glucose metabolism and protein glycosylation, as well as peripheral nervous system development. Genetic interaction with 18w and Toll-6 suggests a Tollo role in convergent extension during early embryogenesis. [Date last reviewed: 2019-03-14]
FBgn0029117	Surf1	Surfeit 1	Surfeit 1 (Surf1) encodes a nuclear gene encoding a protein that might be involved in the assembly of the mitochondrial respiratory chain Cytochrome Oxidase (COX or Complex IV). Mutations in its human ortholog Surf1 are related to Leigh Syndrome with COX deficiency (LScox). Surf1 RNAi knockdown produces many of the hallmark signs of LScox, albeit with a more complex biochemical profile. [Date last reviewed: 2019-03-14]
FBgn0029118	ScsbetaG	Succinyl-coenzyme A synthetase beta subunit, GDP-forming	Succinyl-coenzyme A synthetase β subunit, GDP-forming (ScsβG) encodes a subunit of the ligase that converts succinate to succinyl-CoA. It is involved in cuticle pigmentation. [Date last reviewed: 2019-09-12]
FBgn0029121	Sras	severas	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0029131	Debcl	Death executioner Bcl-2	Death executioner Bcl-2 (Debcl) encodes a pro-apoptotic member of the Bcl-2 family involved in programmed cell death. [Date last reviewed: 2019-07-11]
FBgn0029133	REG	Proteasome regulator gamma	REG (REG) encodes an endopeptidase regulator involved in the regulation of the mitotic G1/S transition and proteasomal protein catabolism. [Date last reviewed: 2019-09-19]
FBgn0029134	Prosbeta5	Proteasome beta5 subunit	Proteasome β5 subunit (Prosβ5) encodes an endopeptidase subunit of the of the 26S proteasome. [Date last reviewed: 2019-09-26]
FBgn0029147	NtR	NtR	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0029148	NHP2	NHP2	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0029152	Mkrn1	Makorin 1	NA
FBgn0029155	Men-b	Malic enzyme b	NA
FBgn0029157	ssh	slingshot	slingshot (ssh) encodes a protein that plays a pivotal role in actin dynamics by reactivating/dephosphorylating the product of tsr in vivo. [Date last reviewed: 2019-03-14]
FBgn0029158	Las	Lipoic acid synthase	NA
FBgn0029167	Hml	Hemolectin	Hemolectin (Hml) encodes a large multidomain protein produced by hemocytes and involved in the clotting reaction. [Date last reviewed: 2019-03-07]
FBgn0029174	Fkbp59	FK506-binding protein 59kD	FK506-binding protein 59kD (Fkbp59) encodes a peptidylprolyl isomerase involved in the regulation of calcium transport and phototransduction. [Date last reviewed: 2019-09-19]
FBgn0029176	eEF1gamma	eukaryotic translation elongation factor 1 gamma	eukaryotic translation elongation factor 1 gamma (eEF1γ) encodes a protein that associates with other EF1 subunits (α/β/δ). It regulates organelle movement along microtubules. It binds tubulin and the protein kinase encoded by Doa, which in turns phosphorylates the product of eEF1γ. [Date last reviewed: 2019-03-07]
FBgn0029502	Coq7	Coenzyme Q7	NA
FBgn0029503	mora	morgana	morgana (mora) encodes an evolutionarily conserved co-chaperone of the product of Hsp83 that controls neuronal cell growth in the context of dendrite remodeling. Dendritic growth and branching are controlled by at least partly separate mechanisms. The Insulin/IGF signaling (IIS)/TORC1 pathways control both growth and branching to avert underdevelopment, whereas the products of mora and rictor realize proportional scaling of the entire arbor. [Date last reviewed: 2019-03-07]
FBgn0029504	CHES-1-like	Checkpoint suppressor 1-like	Checkpoint suppressor 1-like (CHES-1-like) encodes a transcription factor that regulates the division of cardiac progenitor cells and dpp transcription in testis. [Date last reviewed: 2019-09-12]
FBgn0029506	Tsp42Ee	Tetraspanin 42Ee	NA
FBgn0029507	Tsp42Ed	Tetraspanin 42Ed	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0029512	Aos1	Activator of SUMO 1	Activator of SUMO 1 (Aos1) encodes one of two subunits (along with the product of Uba2) of the heterodimeric SUMO activating enzyme. [Date last reviewed: 2019-03-07]
FBgn0029514	CG9166	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0029521	Or1a	Odorant receptor 1a	Odorant receptor 1a (Or1a) encodes a multi-transmembrane chemoreceptor that mediates response to volatile chemicals. [Date last reviewed: 2019-03-14]
FBgn0029525	CG18273	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0029526	CR18166	NA	NA
FBgn0029529	CG13365	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0029594	Coa8	Cytochrome c oxidase assembly factor 8	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0029596	CG14054	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0029608	CG3091	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0029629	eIF3g1	eukaryotic translation initiation factor 3 subunit g1	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0029648	CG3603	NA	NA
FBgn0029659	CG16782	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0029660	CG10801	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0029661	CG16781	NA	NA
FBgn0029662	CG12206	NA	NA
FBgn0029663	CG10804	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0029664	CG10802	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0029665	CG14270	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0029666	CG10803	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0029672	CG2875	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0029676	HIP-R	Hsc/Hsp70-interacting protein related	Hsc/Hsp70-interacting protein related (HIP-R) encodes an ortholog of the human Hsp70 interacting protein (HIP), which is a co-chaperone that stabilizes the ADP-bound conformation of Hsp70. [Date last reviewed: 2018-10-11]
FBgn0029685	CG2938	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0029686	Glos	Gaulos	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0029687	Vap33	VAMP-associated protein 33kDa	VAMP-associated protein 33kDa (Vap33) encodes a protein that plays a conserved role in synaptic homeostasis. It controls a number of processes which depend on phosphoinositide levels, such as synaptic growth and axonal transport. It binds to the product of Sac1 to maintain normal levels of phosphoinositides and to the product of Dscam1 to affect its localization within axonal projections. [Date last reviewed: 2019-03-21]
FBgn0029688	lva	lava lamp	lava lamp (lva) encodes a microfilament/microtubule-associated protein involved in cellularization, Golgi localization, and dendrite morphogenesis. [Date last reviewed: 2019-07-11]
FBgn0029689	CG6428	NA	NA
FBgn0029693	Cmtr1	Cap methyltransferase 1	NA
FBgn0029706	CG3626	NA	NA
FBgn0029709	CHOp24	CHOp24	CHOp24 (CHOp24) encodes a p24 transporter that contributes to the intracellular trafficking between the ER and Golgi. It is required for secretion of Wnt ligands. [Date last reviewed: 2019-09-12]
FBgn0029711	Usf	Usf	Usf (Usf) encodes a bHLH family transcription factor that recognizes E-boxes in the Ste promoter. [Date last reviewed: 2019-03-21]
FBgn0029713	CG11436	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0029714	CG3527	NA	NA
FBgn0029715	CG11444	NA	NA
FBgn0029718	mRpL30	mitochondrial ribosomal protein L30	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0029736	CG4041	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0029737	CG6903	NA	NA
FBgn0029755	Sas10	Something about silencing 10	Something about silencing 10 (Sas10) encodes a protein belonging to the SAS10 family. It might be a substrate of the RNA deaminase encoded by Adar, which shows an adenosine to inosine (A-to-I) deaminase activity in pre-mRNA transcripts. The noncoding strand of the adjacent gene, Rnp4F, reads through to form a duplex with Sas10 transcripts at their 3'-end to target both transcripts for promiscuous A-to-I editing and degradation. [Date last reviewed: 2018-10-11]
FBgn0029756	CG3309	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0029763	Usp16-45	Ubiquitin specific protease 16/45	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0029766	CG15784	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0029771	CG12730	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0029778	RhoGAP5A	Rho GTPase activating protein at 5A	Rho GTPase activating protein at 5A (RhoGAP5A) encodes a GTPase activating protein involved in adherens junction maintenance and regulation of ERK MAP kinase signaling [Date last reviewed: 2019-08-01]
FBgn0029783	Sirt4	Sirtuin 4	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0029785	RpL35	Ribosomal protein L35	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0029789	PGAP1	Post-GPI attachment to proteins 1	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0029791	AdamTS-B	ADAM metallopeptidase with thrombospondin type 1 motif B	NA
FBgn0029798	CG4078	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0029799	CG15772	NA	NA
FBgn0029800	lin-52	lin-52	lin-52 (lin-52) encodes a subunit of the MuvB core complex. The MuvB core binds to the oncoprotein encoded by Myb and the Rbf-E2f2-Dp tumor suppressor complex, thereby controlling the expression of many genes, including critical regulators of the cell cycle. [Date last reviewed: 2019-03-21]
FBgn0029801	CG15771	NA	NA
FBgn0029813	AgmNAT	Agmatine N-acetyltransferase	NA
FBgn0029818	GAA1	Glycosylphosphatidylinositol anchor attachment 1	Glycosylphosphatidylinositol anchor attachment 1 (GAA1) encodes a subunit of glycosylphosphatidylinositol (GPI) transamidase, which mediates GPI anchoring in the endoplasmic reticulum. GPI anchor attachment serves as a general mechanism for linking proteins to the cell surface membrane. [Date last reviewed: 2019-03-07]
FBgn0029819	Usp30	Ubiquitin specific protease 30	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0029820	CG16721	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0029821	CG4020	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0029822	CG12236	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0029823	Shmt	Serine hydroxymethyl transferase	Serine hydroxymethyl transferase (Shmt) encodes a conserved pyridoxal phosphate-containing enzyme that converts serine into glycine and N5,N10-methylentetrahydrofolate. This reaction represents a major source for activated C1 units and tetrahydrofolate-mediated C1 metabolism. [Date last reviewed: 2018-10-11]
FBgn0029824	CG3726	NA	NA
FBgn0029825	CG12728	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0029833	MCTS1	Malignant T cell amplified sequence 1	Malignant T cell amplified sequence 1 (MCTS1) encodes a protein that, together with its binding partner encoded by DENR, is a non-canonical translation initiation factor. It associates with ribosomes and it promotes translation reinitiation. [Date last reviewed: 2019-03-14]
FBgn0029840	raptor	raptor	raptor (raptor) encodes a crucial component of target of rapamycin (TOR) complex 1, which is a conserved regulator of cell growth and metabolism. [Date last reviewed: 2018-10-11]
FBgn0029849	Efr	ER GDP-fucose transporter	ER GDP-fucose transporter (Efr) encodes ER GDP-fucose transporter is the multifunctional nucleotide sugar transporter that transports GDP-fucose, UDP-GlcNAc and UDP-Xyl from cytosol into the lumen of ER. [Date last reviewed: 2019-03-07]
FBgn0029853	CG3781	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0029854	CG3566	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0029856	CG11700	NA	NA
FBgn0029857	wuho	wuho	NA
FBgn0029858	mldr	mulder	mulder (mldr) encodes a protein involved in mitochondrial tRNA processing. [Date last reviewed: 2019-09-12]
FBgn0029861	CG3815	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0029867	CG3847	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0029868	ND-B16.6	NADH dehydrogenase (ubiquinone) B16.6 subunit	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0029870	Marf	Mitochondrial assembly regulatory factor	Mitochondrial assembly regulatory factor (Marf) encodes a dynamin-family GTPase that mediates outer mitochondrial membrane tethering and fusion. Marf loss causes mitochondrial fragmentation and endoplasmic reticular stress that evoke skeletal muscle, retinal and heart tube dysfunction. [Date last reviewed: 2019-03-14]
FBgn0029873	CG3918	NA	NA
FBgn0029874	CG3342	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0029878	Pat1	Protein interacting with APP tail-1	Protein interacting with APP tail-1 (Pat1) encodes a protein required for the product of Khc to transport cargo and to maximize its motility. In oocytes the products of Pat1 and Klc act in a redundant manner. [Date last reviewed: 2019-03-14]
FBgn0029881	pigs	pickled eggs	NA
FBgn0029882	CG3226	NA	NA
FBgn0029885	CG3224	NA	NA
FBgn0029887	CG3198	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0029888	ND-ASHI	NADH dehydrogenase (ubiquinone) ASHI subunit	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0029890	Fum2	Fumarase 2	NA
FBgn0029891	Pink1	PTEN-induced putative kinase 1	PTEN-induced putative kinase 1 (Pink1) is the ortholog of human PINK1, a gene mutated in autosomal recessive Parkinson's disease. Pink1 encodes a mitochondrially targeted Ser-Thr kinase. It has been linked to a number of cellular functions including altering mitochondrial dynamics, the autophagic degradation of dysfunctional mitochondria, and the proper function of Complex I of the electron transport chain. [Date last reviewed: 2018-10-11]
FBgn0029892	CG3184	NA	NA
FBgn0029893	CG14442	NA	NA
FBgn0029894	CG14440	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0029895	CG14441	NA	NA
FBgn0029896	CG3168	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0029897	RpL17	Ribosomal protein L17	NA
FBgn0029903	pod1	pod1 coronin	pod1 (pod1) encodes a microtubule and actin filament binding protein involved in actin cytoskeleton reorganization and axon guidance. [Date last reviewed: 2019-09-19]
FBgn0029905	Nf-YC	Nuclear factor Y-box C	Nuclear factor Y-box C (Nf-YC) encodes a transcription factor involved in axon guidance. [Date last reviewed: 2019-09-12]
FBgn0029906	xit	xiantuan	xiantuan (xit) encodes a glucosyl transferase enzyme in the N-glycosylation pathway of the endoplasmic reticulum. It adds the three terminal glucose residues to oligosaccharyl-dolichol before the oligosaccharyl is transferred to newly synthesized proteins. It contributes to the control of gastrulation movements. [Date last reviewed: 2019-03-21]
FBgn0029911	CG14435	NA	NA
FBgn0029912	CG4557	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0029913	Cht11	Chitinase 11	NA
FBgn0029914	CG4558	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0029915	CG14434	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0029924	CG4586	NA	NA
FBgn0029925	CG3040	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0029929	CG4593	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0029935	CG4615	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0029936	CG4617	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0029937	CG8300	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0029941	CG1677	NA	NA
FBgn0029942	CG2059	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0029943	Atg5	Autophagy-related 5	NA
FBgn0029944	Dok	Downstream of kinase	Downstream of kinase (Dok) encodes a membrane-associated protein that functions upstream of the product of Shark to activate Jun kinase signaling during embryonic dorsal closure. [Date last reviewed: 2019-03-07]
FBgn0029957	CG12155	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-10-13]
FBgn0029958	Pdp	Pyruvate dehydrogenase phosphatase	Pyruvate dehydrogenase phosphatase (Pdp) encodes an enzyme that regulates the BMP/DPP pathway via dephosporylation of the product encoded by Mad. [Date last reviewed: 2019-08-01]
FBgn0029959	Rab39	Rab39	NA
FBgn0029968	Ir7g	Ionotropic receptor 7g	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0029969	CG10932	NA	NA
FBgn0029970	Nek2	Nek2	Nek2 (Nek2) encodes a Ser/Thr kinase belonging to the NIMA family of kinases. It regulates centrosome disjunction, bipolar spindle formation, and kinetochore microtubule dynamics during mitosis. It also participates in meiosis by regulating chromatin condensation events. [Date last reviewed: 2018-10-11]
FBgn0029971	ND-MNLL	NADH dehydrogenase (ubiquinone) MNLL subunit	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0029974	dpr14	defective proboscis extension response 14	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0029975	spidey	spidey	spidey (spidey) encodes a member of the short chain dehydrogenase/reductase family. It regulates oenocyte growth and maturation, as well as the metabolism of ecdysteroids and cuticular hydrocarbons. [Date last reviewed: 2018-10-11]
FBgn0029976	snz	snazarus	snazarus (snz) encodes a sorting nexin protein involved in lifespan. [Date last reviewed: 2019-03-14]
FBgn0029977	hdm	hold'em	hold'em (hdm) encodes an enzyme involved in photoreceptor synaptic transmission. [Date last reviewed: 2019-09-26]
FBgn0029979	mahe	maheshvara	maheshvara (mahe) encodes an RNA helicase. [Date last reviewed: 2020-03-05]
FBgn0029980	Dhdds	Dehydrodolichyl diphosphate synthase subunit	NA
FBgn0029992	Upf2	Upf2	Upf2 (Upf2) encodes a protein required for nonsense-mediated mRNA decay (NMD). It interacts directly with the product of Upf1 to identify and degrade NMD-substrate mRNAs, including mRNAs containing premature termination codons and a number of normal endogenous mRNAs. [Date last reviewed: 2019-03-21]
FBgn0029996	UbcE2H	Ubiquitin conjugating enzyme E2H	Ubiquitin conjugating enzyme E2H (UbcE2H)encodes an E2 enzyme involved in protein ubiquitylation. It is involved in response to viral infection. [Date last reviewed: 2019-07-11]
FBgn0029997	CG2258	NA	NA
FBgn0029999	CG1575	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030000	CG2260	NA	NA
FBgn0030001	cyr	cypher	NA
FBgn0030003	CG2116	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030004	CG10958	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030006	CG17982	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-10-13]
FBgn0030007	alpha-PheRS	Phenylalanyl-tRNA synthetase, alpha-subunit	Phenylalanyl-tRNA synthetase, α-subunit (α-PheRS) encodes a cytoplasmic aminoacyl-tRNA synthetase that catalyzes the ligation of Phenylalanine to its cognate tRNAPhe. Together with the β-subunit it forms a tetrameric enzyme complex. This subunit provides the catalytic core. [Date last reviewed: 2019-03-21]
FBgn0030008	CG2129	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030010	CG10959	NA	NA
FBgn0030012	CG18262	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030013	GIIIspla2	Phospholipase A2 group III	NA
FBgn0030017	CG2278	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030018	slpr	slipper	NA
FBgn0030025	CG2147	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030026	sni	sniffer	sniffer (sni) encodes a homodimeric carbonyl reductase that belongs to the SDR superfamily of proteins. It catalyzes the reduction of the lipid derived aldehyde 4-oxononenal. It contributes to protection against oxidative stress-induced neurodegeneration and prevention of apoptosis by removal of damaged cardiolipin. [Date last reviewed: 2019-03-14]
FBgn0030028	Corp	Companion of reaper	Companion of reaper (Corp) is a gene that is transcriptionally induced following DNA damage. It may function to inhibit the pro-apoptotic activity of the transcriptional factor encoded by p53. [Date last reviewed: 2018-10-11]
FBgn0030030	CG1636	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030034	CG10555	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030035	PIG-T	Phosphatidylinositol glycan anchor biosynthesis class T	NA
FBgn0030037	Miga	Mitoguardin	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030038	CG1440	NA	NA
FBgn0030039	CG12123	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030040	CG15347	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030041	CG12116	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030048	CG12112	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030049	Trf4-1	Topoisomerase related function 4-1	NA
FBgn0030052	CG12065	NA	NA
FBgn0030053	CG12081	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030054	Caf1-180	Chromatin assembly factor 1, p180 subunit	Chromatin assembly factor 1, p180 subunit (Caf1-180) encodes a component of the chromatin assembly factor-1, which couples DNA replication to histone deposition. The product of Caf1-180 is involved in nucleosome organization, DNA endoduplication and double-strand DNA break repair. [Date last reviewed: 2019-08-01]
FBgn0030055	Rubicon	Rubicon	NA
FBgn0030056	CAH3	Carbonic anhydrase 3	NA
FBgn0030057	Ppt1	Palmitoyl-protein thioesterase 1	Palmitoyl-protein thioesterase 1 (Ppt1) encodes a lysosomal enzyme that removes palmitoyl groups from particular target proteins during protein degradation within the lysosomal compartment. Palmitoylation is critical for the cellular localization and modulation of many signaling proteins. [Date last reviewed: 2019-03-14]
FBgn0030060	CG2004	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030061	CG1785	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030063	CG1789	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030065	CG12075	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030066	Uros1	Uroporphyrinogen III synthase 1	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030067	Rbm13	RNA-binding motif protein 13	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030071	CG12661	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030073	CG10962	NA	NA
FBgn0030077	CG15365	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0030081	CG7246	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030082	HP1b	Heterochromatin Protein 1b	Heterochromatin Protein 1b (HP1b) encodes a chromatin binding protein that negatively regulates transcription and heterochromatin formation. [Date last reviewed: 2019-03-07]
FBgn0030086	CCT2	Chaperonin containing TCP1 subunit 2	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030087	CG7766	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030088	Arfrp1	ADP-ribosylation factor related protein 1	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030089	AP-1gamma	Adaptor Protein complex 1, gamma subunit	Adaptor Protein complex 1, γ subunit (AP-1γ) encodes a clathrin adaptor involved in vesicle trafficking. [Date last reviewed: 2019-07-11]
FBgn0030090	fend	forked end	forked end (fend) encodes a transmembrane protein that contributes to selective target selection in the neuromuscular system. [Date last reviewed: 2019-03-07]
FBgn0030091	CG7065	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030092	fh	frataxin	frataxin (fh) encodes an essential nuclear encoded protein located in the mitochondrial inner membrane. It is involved in the synthesis of iron-sulfur clusters which are required for ATP production by the respiratory chain as well as other biological processes such as steroidogenesis. The levels of the product of fh are also crucial for protection of the product of mAcon1 against oxidative stress and iron homeostasis. [Date last reviewed: 2019-03-07]
FBgn0030093	Bap111	Brahma associated protein 111kD	Brahma associated protein 111kD (Bap111) encodes a protein important for Brahma complex function. It is involved in chromatin remodeling and transcription induction. [Date last reviewed: 2019-08-01]
FBgn0030096	Zpr1	Zpr1	Zpr1 (Zpr1) encodes a protein that functions downstream of the EGFR and other tyrosine kinase receptors. It also contributes to the assembly of spliceosome snRNPs. In the developing tracheal system it is required for terminal cell lumen formation. [Date last reviewed: 2019-03-21]
FBgn0030099	CG12056	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030100	CG12106	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030101	CG12118	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030109	CG12121	NA	NA
FBgn0030114	CG17754	NA	NA
FBgn0030121	Cfp1	CXXC finger protein 1	CXXC finger protein 1 (Cfp1) encodes a protein that is thought to help target the Set1/COMPASS histone methyltransferase complex to CpG rich regions of the genome, including gene promoters. [Date last reviewed: 2019-03-07]
FBgn0030122	Aladin	Aladin	NA
FBgn0030136	RpS28b	Ribosomal protein S28b	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030137	CG15317	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-10-13]
FBgn0030141	Gga	Golgi-localized, gamma-adaptin ear containing, ARF binding protein	Golgi-localized, γ-adaptin ear containing, ARF binding protein (Gga) encodes a clathrin binding protein involved in post-Golgi vesicle-mediated transport. [Date last reviewed: 2019-07-11]
FBgn0030151	CG1354	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030170	CG2990	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030177	CG2972	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030178	Naxe	NAD(P)HX epimerase	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030183	Ypel	Yippee-like	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030189	CG2909	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030196	Psf3	Partner of Sld Five 3	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030206	CG2889	NA	NA
FBgn0030208	PPP4R2r	Protein phosphatase 4 regulatory subunit 2-related protein	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030217	CG2124	NA	NA
FBgn0030218	CG1628	NA	NA
FBgn0030228	BTBD9	BTB (POZ) domain containing 9	BTB (POZ) domain containing 9 (BTBD9) encodes a protein that regulates brain dopamine levels and the circadian sleep/wake cycle. [Date last reviewed: 2019-09-19]
FBgn0030230	Rph	Rabphilin	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030234	CG15211	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030237	CG15209	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030239	CG17333	NA	NA
FBgn0030240	CG2202	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030241	feo	fascetto	fascetto (feo) encodes a protein that binds the central spindle microtubules and is required for proper midbody formation and cytokinesis. It also has roles in centrosome duplication and neurogenesis. [Date last reviewed: 2019-03-07]
FBgn0030242	sofe	sister of feo	NA
FBgn0030243	CG2186	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030245	CG1637	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030246	CG1582	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030263	CG2076	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030266	CG11122	NA	NA
FBgn0030268	Klp10A	Kinesin-like protein at 10A	Kinesin-like protein at 10A (Klp10A) encodes a member of the kinesin superfamily of motor proteins (KIF) and of the kinesin-13 family of microtubule depolymerases. It induces microtubule depolymerization to regulate the length and dynamics of microtubules in a variety of cell processes and structures such as the mitotic and meiotic spindles, the centriole and interphase microtubules. [Date last reviewed: 2018-10-11]
FBgn0030269	CDK2AP1	CDK2-associated protein 1	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030271	CG15202	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030274	Lint-1	l(3)mbt interacting protein 1	l(3)mbt interacting protein 1 (Lint-1) encodes a nuclear protein that associates with the product of l(3)mbt in the LINT complex. It is involved in the repression of malignant brain tumor signature (MBTS) genes. [Date last reviewed: 2019-09-26]
FBgn0030276	Dlic	Dynein light intermediate chain	Dynein light intermediate chain (Dlic) encodes a dynein subunit that contributes to microtubule-based movement. It is involved in axogenesis, dendrite morphogenesis, mRNA transport, oogenesis and mitosis. [Date last reviewed: 2019-09-26]
FBgn0030286	Gapvd1	GTPase activating protein and VPS9 domains 1	NA
FBgn0030289	GCS1	Glucosidase 1	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030291	CG1738	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-10-13]
FBgn0030292	CG11752	NA	NA
FBgn0030293	CG1737	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030300	Sk1	Sphingosine kinase 1	Sphingosine kinase 1 (Sk1) encodes an enzyme that catalyzes the phosphorylation of sphingosine to sphingosine 1-phosphate, a bioactive lipid mediator. It regulates cell proliferation, differentiation, endolysosomal trafficking and muscle cell repair. [Date last reviewed: 2019-03-14]
FBgn0030301	HP5	Heterochromatin protein 5	Heterochromatin protein 5 (HP5) encodes a component of classical heterochromatin that is involved in gene silencing by heterochromatin. [Date last reviewed: 2018-10-04]
FBgn0030305	Uba5	Ubiquitin-like activating enzyme 5	Ubiquitin-like activating enzyme 5 (Uba5) encodes a member of the E1-like ubiquitin-activating enzyme family. It activates the protein encoded by Ufm1, and acts as a key factor in the ufmylation process. It is involved in ATP binding, catalytic activity, cofactor binding, metal ion binding, nucleotide binding and oxidoreductase activity. [Date last reviewed: 2019-09-26]
FBgn0030306	Spase25	Spase 25-subunit	NA
FBgn0030309	CG1572	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030310	PGRP-SA	Peptidoglycan recognition protein SA	Peptidoglycan recognition protein SA (PGRP-SA) encodes a secreted protein that mediates Toll pathway activation during bacterial infection. It binds to peptidoglycans and, together with the product of GNBP1, activates the serine protease encoded by modSP. [Date last reviewed: 2019-03-14]
FBgn0030311	CG11699	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0030314	CG11696	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030316	CG11695	NA	NA
FBgn0030317	pkm	Pinkman	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030318	rho-4	rhomboid-4	rhomboid-4 (rho-4) encodes a member of the rhomboid superfamily of intramembrane serine proteases, which cleave to release proteins from the membrane. It processes the transmembrane EGF ligands encoded by spi, Krn, and grk. Its activity is directly and dramatically stimulated by calcium. [Date last reviewed: 2018-10-04]
FBgn0030320	CG2247	NA	NA
FBgn0030321	CG1703	NA	NA
FBgn0030323	Vlet	Valette	NA
FBgn0030326	CG2444	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030327	FucT6	alpha1,6-fucosyltransferase	NA
FBgn0030328	Amun	Amun	NA
FBgn0030329	prtp	pretaporter	pretaporter (prtp) encodes a ligand for the engulfment receptor encoded by drpr. It resides in the endoplasmic reticulum. During apoptosis it is exposed at the cell surface where it binds the product of drpr to induce phagocytosis. [Date last reviewed: 2019-03-14]
FBgn0030330	Tango10	Transport and Golgi organization 10	NA
FBgn0030331	CG15221	NA	NA
FBgn0030332	CG9360	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030334	Karl	Karl	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030336	CG1578	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030340	CG15740	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030341	p24-1	p24-related-1	p24-related-1 (p24-1) encodes a p24 protein that contributes to the secretion of Wnt ligands. [Date last reviewed: 2019-09-12]
FBgn0030342	CG10347	NA	NA
FBgn0030343	ATP7	ATP7	ATP7 (ATP7) encodes a copper transmembrane transporter involved in cuticle pigmentation, copper homeostasis and larval development. [Date last reviewed: 2019-09-12]
FBgn0030344	Nrd1	Nardilysin	Nardilysin (Nrd1) encodes a protein involved in chaperone-mediated protein folding. [Date last reviewed: 2019-09-12]
FBgn0030345	CG1847	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030346	BORCS5	BLOC-1 related complex subunit 5	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030347	CG15739	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030349	CG10353	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030350	SelG	Selenoprotein G	Selenoprotein G (SelG) encodes a type III Golgi apparatus transmembrane protein. It is implicated in the release of Ca[2+] from the endoplasmic reticulum to the cytosol by regulating the expression of genes participating in the inositol 1,4,5-tris-phosphate pathway. [Date last reviewed: 2019-03-14]
FBgn0030351	CG1840	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-10-13]
FBgn0030352	sicily	severe impairment of CI with lengthened youth	NA
FBgn0030354	Upf1	Upf1 RNA helicase	NA
FBgn0030357	Sclp	Sclp	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030358	CG10362	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030361	CG1492	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030362	regucalcin	regucalcin	NA
FBgn0030364	Lsm12a	LSM12 homolog a	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030365	Tango4	Transport and Golgi organization 4	NA
FBgn0030366	Usp7	Ubiquitin-specific protease 7	NA
FBgn0030367	Cyp311a1	Cytochrome P450 311a1	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030369	Cyp318a1	Cytochrome P450 318a1	NA
FBgn0030373	moon	moonshiner	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030391	Rab40	Rab40	NA
FBgn0030396	CG2556	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0030400	Pits	Protein interacting with Ttk69 and Sin3A	NA
FBgn0030403	CG1824	NA	NA
FBgn0030406	CG1463	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030407	Fpgs	Folylpolyglutamate synthase	NA
FBgn0030410	Aven	Apoptosis and caspase activation inhibitor	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030411	CG2540	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030412	Tomosyn	Tomosyn	Tomosyn (Tomosyn) encodes a protein involved in long-term memory and neuromuscular synaptic transmission. [Date last reviewed: 2019-09-19]
FBgn0030417	CG15725	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030418	CG4004	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030420	CG12717	NA	NA
FBgn0030421	Agpat1	1-Acylglycerol-3-phosphate O-acyltransferase 1	NA
FBgn0030431	CG4407	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030432	CG4404	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030433	mRpL49	mitochondrial ribosomal protein L49	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030434	Brms1	BRMS1 transcriptional repressor	BRMS1 (Brms1) encodes a protein involved in regulation of the ecdysone signaling and the Notch signaling pathway in the wing. [Date last reviewed: 2019-09-19]
FBgn0030435	CG4645	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030447	CG2200	NA	NA
FBgn0030451	CG15717	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030452	MFS10	Major Facilitator Superfamily Transporter 10	NA
FBgn0030456	CG4332	NA	NA
FBgn0030457	CG12096	NA	NA
FBgn0030460	Coq5	Coenzyme Q5	NA
FBgn0030465	CG15743	NA	NA
FBgn0030466	CG15744	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030467	CG1764	NA	NA
FBgn0030468	CG1622	NA	NA
FBgn0030474	CG15747	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030478	CG1640	NA	NA
FBgn0030479	Rbp1-like	Rbp1-like	Rbp1-like (Rbp1-like) encodes a mRNA binding protein involved in RNA splicing and RNA metabolism. [Date last reviewed: 2019-09-12]
FBgn0030480	Tim9a	Tim9a	Tim9a (Tim9a) encodes a subunit of the soluble mitochondrial intermembrane space protein transporter complex that acts as a chaperone for the import and insertion of proteins into the mitochondrial inner membrane. [Date last reviewed: 2021-01-21]
FBgn0030481	CG1662	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030482	CG1673	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030484	GstT4	Glutathione S transferase T4	NA
FBgn0030485	CG1998	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030486	Set2	SET domain containing 2	SET domain containing 2 (Set2) encodes an essential histone methyltransferase that marks active gene bodies with H3K36me3. [Date last reviewed: 2019-03-14]
FBgn0030499	CG11178	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030500	Ndc80	Ndc80	Ndc80 (Ndc80) encodes a protein involved in mitotic metaphase plate congression. [Date last reviewed: 2019-09-26]
FBgn0030501	BthD	BthD selenoprotein	BthD selenoprotein (BthD) encodes a protein involved in salivary gland development and lifespan determination. [Date last reviewed: 2019-09-19]
FBgn0030502	tth	toothrin	NA
FBgn0030503	Tango2	Transport and Golgi organization 2	NA
FBgn0030504	CG2691	NA	NA
FBgn0030505	NFAT	NFAT nuclear factor	NA
FBgn0030506	DNAlig4	DNA ligase 4	DNA ligase 4 (DNAlig4) encodes an ATP-dependent DNA ligase responsible for the sealing of DNA double-strand breaks during the canonical non-homologous end joining pathway of DNA repair. It interacts with the product of XRCC4 for stability and DNA ligase activity. [Date last reviewed: 2018-10-04]
FBgn0030507	CG11164	NA	NA
FBgn0030510	CG12177	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030511	CG11158	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-10-13]
FBgn0030512	Nadsyn	NAD synthetase	NA
FBgn0030514	CG9941	NA	NA
FBgn0030518	CG11134	NA	NA
FBgn0030519	CG11151	NA	NA
FBgn0030520	Pdcd4	Programmed cell death 4	NA
FBgn0030521	CtsB	Cathepsin B	Cathepsin B1 (CtsB1) encodes a papain-like cysteine proteinase involved in lysosomal protein degradation. [Date last reviewed: 2019-03-07]
FBgn0030522	CG11103	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030528	CG11095	NA	NA
FBgn0030529	Clic	Chloride intracellular channel	Chloride intracellular channel (Clic) encodes a protein involved in chloride transport and alcohol-related behavior. [Date last reviewed: 2019-08-01]
FBgn0030530	jub	Ajuba LIM protein	Ajuba LIM protein (jub) encodes a LIM domain-containing protein that binds to and inhibits activation of the Hippo pathway kinase encoded by wts. It localizes to adherens junctions in a tension-dependent manner. [Date last reviewed: 2019-03-07]
FBgn0030545	CG11590	NA	NA
FBgn0030552	mRpL38	mitochondrial ribosomal protein L38	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030554	CG1434	NA	NA
FBgn0030555	Fbxl4	F box and leucine-rich-repeat gene 4	NA
FBgn0030556	mRNA-cap	mRNA-capping-enzyme	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030571	CG14414	NA	NA
FBgn0030572	mRpS25	mitochondrial ribosomal protein S25	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030575	CG5321	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030576	CG15890	NA	NA
FBgn0030581	CG14408	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030582	CG14411	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030583	CG14410	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-10-13]
FBgn0030584	CG14407	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030588	CG9521	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030598	CG9503	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030600	hiw	highwire	NA
FBgn0030603	CG5541	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030605	ND-B18	NADH dehydrogenase (ubiquinone) B18 subunit	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030610	Cox17	Cytochrome c oxidase copper chaperone COX17	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030611	CG15027	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030612	Dbct	Dihydrolipoamide branched chain transacylase E2	NA
FBgn0030615	Cyp4s3	Cytochrome P450 4s3	NA
FBgn0030616	RpL37a	Ribosomal protein L37a	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030625	CG5877	NA	NA
FBgn0030628	CG9114	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030629	CG9123	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030630	CG12608	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030631	Prp5	pre-mRNA processing factor 5	NA
FBgn0030638	CG11655	NA	NA
FBgn0030645	Alg14	ALG14, UDP-N-acetylglucosaminyltransferase subunit	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030648	CG6340	NA	NA
FBgn0030653	CG7860	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030654	CG15643	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030655	CG9213	NA	NA
FBgn0030657	cerv	cervantes	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030658	CG7872	NA	NA
FBgn0030659	CG9215	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030660	CG8097	NA	NA
FBgn0030662	Chsy	Chondroitin sulfate synthase	NA
FBgn0030667	CG15599	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0030668	CG8128	NA	NA
FBgn0030669	CG9240	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030670	Pis	Phosphatidylinositol synthase	Phosphatidylinositol synthase (Pis) encodes an enzyme involved in the synthesis of phosphatidyl inositol, which is further modified to give rise to phosphorylated membrane lipids with multiple functions. It is important for membrane composition and Pis mutants develop various cellular polarity abnormalities, e.g. epithelial cells will misposition basement membrane proteins at their apical side, due to a lack of PIP2. [Date last reviewed: 2018-10-04]
FBgn0030671	CG8134	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0030672	CG9281	NA	NA
FBgn0030673	CG15601	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-10-13]
FBgn0030674	HUWE1	HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030675	CG8191	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-10-13]
FBgn0030678	CG11679	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0030679	CG8206	NA	NA
FBgn0030680	CG8944	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030683	Mvd	Mevalonate diphosphate decarboxylase	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030685	Graf	GTPase regulator associated with FAK	NA
FBgn0030686	mRpL3	mitochondrial ribosomal protein L3	NA
FBgn0030687	Polr3A	RNA polymerase III subunit A	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030692	mRpS30	mitochondrial ribosomal protein S30	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030693	sordd1	suppression of retinal degeneration disease 1 upon overexpression 1	NA
FBgn0030694	CG15602	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030695	PGRP-LE	Peptidoglycan recognition protein LE	Peptidoglycan recognition protein LE (PGRP-LE) encodes an intracellular protein that interacts with DAP-type peptidoglycan to activate the immune deficiency pathway, notably in the midgut. [Date last reviewed: 2019-03-14]
FBgn0030699	CG8578	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030700	CG15914	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0030701	CG16952	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030703	MSBP	membrane steroid binding protein	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030704	CG15916	NA	NA
FBgn0030710	CG8924	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030711	Rrp47	Ribosomal RNA processing 47	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030716	CG9170	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030717	Slc25A46a	Solute carrier family 25 member 46a	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030718	ND-20	NADH dehydrogenase (ubiquinone) 20 kDa subunit	NADH dehydrogenase (ubiquinone) 20 kDa subunit (ND-20) encodes a component of the mitochondrial electron transport chain and is involved in determination of life span. [Date last reviewed: 2019-09-26]
FBgn0030719	eIF5	eukaryotic translation initiation factor 5	NA
FBgn0030720	CG8939	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030721	CG12698	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0030724	Nipsnap	Nipsnap	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030731	Mfe2	peroxisomal Multifunctional enzyme type 2	peroxisomal Multifunctional enzyme type 2 (Mfe2) encodes a multifunctional protein harboring two separate enzyme activities: 2-enoyl-CoA hydratase 2 and 3-hydroxyacyl-CoA dehydrogenase. They function in the peroxisomal fatty acid breakdown spiral of beta-oxidation utilizing the (R)-isomer of the CoA-containing substrate. [Date last reviewed: 2019-03-14]
FBgn0030733	UQCR-14	Ubiquinol-cytochrome c reductase 14 kDa subunit	NA
FBgn0030734	CG9911	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030735	CG3632	NA	NA
FBgn0030738	CG9915	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030739	SWIP	Strumpellin and WASH-interacting protein	Strumpellin and WASH-interacting protein (SWIP) encodes a protein that is part of the multi-subunit WASH regulatory complex (SHRC) to activate Arp2/3-mediated actin nucleation in a context-dependent manner. The product of SWIP, along with the SHRC, has been found to play a role in actin architecture and ooplasmic streaming during oogenesis, in endosome recycling, and in integrin-mediated cell spreading of hemocytes. [Date last reviewed: 2019-03-21]
FBgn0030740	CG9917	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0030743	CG9921	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030744	CG9992	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-10-13]
FBgn0030745	CG4239	NA	NA
FBgn0030746	CG9981	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030747	CG4301	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030748	Traf-like	TNF-receptor-associated factor-like	NA
FBgn0030749	AnxB11	Annexin B11	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030752	CDC50	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030753	rngo	rings lost	rings lost (rngo) encodes a ubiquitin receptor that binds to ubiquitinated proteins via its ubiquitin-associated domain. It is an essential protein that is required for proper development of ring canals in the female germ line. [Date last reviewed: 2018-10-04]
FBgn0030757	CG9902	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030759	CG13014	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0030761	CG9784	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030766	mthl1	methuselah-like 1	methuselah-like 1 (mthl1) encodes a G protein coupled receptor (GPCR) in the Methuselah clade of GPCRs. It interacts with the secreted morphogen encoded by fog to specify patterns of epithelial tissue folding during gastrulation and wing imaginal disc folding. Upon binding to the product of fog, the product of mthl1 activates apical constriction through the Concertina-RhoGEF2-Rho pathway. [Date last reviewed: 2019-03-14]
FBgn0030768	Nemp	Nuclear envelope integral membrane protein	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030786	mRpL22	mitochondrial ribosomal protein L22	NA
FBgn0030787	CG9609	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030788	Sap30	SIN3-associated polypeptide 30	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030789	Rrp45	Rrp45	NA
FBgn0030790	CG4768	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0030791	CG9132	NA	NA
FBgn0030792	CG4789	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030793	Rai1	Rat1 Interacting Protein 1	NA
FBgn0030794	CG13005	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-10-13]
FBgn0030795	ppk28	pickpocket 28	pickpocket 28 (ppk28) encodes a member of the degenerin/epithelial Na[+] channel (pickpocket) gene family. It is an osmosensitive ion channel that mediates water taste detection. [Date last reviewed: 2019-03-14]
FBgn0030796	CG4829	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030797	CG13004	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-10-13]
FBgn0030799	CG4872	NA	NA
FBgn0030800	Nprl2	Nitrogen permease regulator-like 2	Nitrogen permease regulator-like 2 (Nprl2) encodes a component of the highly conserved GAP activity towards rags 1 (GATOR1) complex, which inhibits the product of Tor activity in response to amino acid starvation. The product of Nprl2, as well as the other GATOR1 components encoded by Nprl3 and Iml1, regulates early meiotic progression. [Date last reviewed: 2019-03-14]
FBgn0030801	Polr3I	RNA polymerase III subunit I	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030802	DENR	Density regulated protein	Density regulated protein (DENR) encodes a non-canonical translation initiation factor together with its binding partner encoded by MCTS1. It associates with ribosomes and it promotes translation reinitiation. [Date last reviewed: 2019-03-07]
FBgn0030803	CG4880	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030805	wus	wurst	wurst (wus) encodes a transmembrane protein essential for clathrin-mediated endocytosis. It recruits the product of Hsc70-4 and clathrin to the apical cell membrane of epithelial cells. The endocytosis mediated by the product of wus is required for size determination and lumen clearance of the airways. [Date last reviewed: 2019-03-21]
FBgn0030806	CG13001	NA	NA
FBgn0030808	RhoGAP15B	Rho GTPase activating protein at 15B	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030809	Ubr1	Ubr1 ubiquitin ligase	NA
FBgn0030812	wcy	wacky	wacky (wcy) encodes a protein involved in habituation, autophagy regulation and TORC1 signaling. [Date last reviewed: 2019-09-19]
FBgn0030813	CG4949	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030816	CG16700	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030833	CG8915	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030834	CG8675	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-10-13]
FBgn0030838	CG5445	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0030839	CG5613	NA	NA
FBgn0030850	stas	Stasimon	NA
FBgn0030851	CG8326	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030853	ND-24	NADH dehydrogenase (ubiquinone) 24 kDa subunit	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030854	CG8289	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030855	CG5800	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030858	IntS2	Integrator 2	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030863	CG8188	NA	NA
FBgn0030864	CG8173	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030869	Socs16D	Suppressor of Cytokine Signaling at 16D	Suppressor of Cytokine Signaling at 16D (Socs16D) encodes a member of the SOCS family. It binds to the product of Pvr when catalytically active and is required for downstream activation of Target of Rapamycin Complex 1, but not the product of rl. [Date last reviewed: 2019-03-14]
FBgn0030871	CG8142	NA	NA
FBgn0030872	Ucp4A	Ucp4A	Ucp4A (Ucp4A) encodes a mitochondrial anion carrier that localizes to the mitochondrial inner membrane and can disrupt the proton gradient generated by the electron transport chain. It is expressed ubiquitously in adult flies, and plays a role in protecting mitochondria from oxidative stress. [Date last reviewed: 2018-10-04]
FBgn0030873	CG15814	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030874	Spt7	Spt7	Spt7 (Spt7) encodes a subunit of the SAGA chromatin modifying complex. [Date last reviewed: 2019-08-01]
FBgn0030876	CG6762	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030877	Arp8	Actin-related protein 8	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030878	CG6769	NA	NA
FBgn0030883	CG7772	NA	NA
FBgn0030884	CG6847	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030890	CG7536	NA	NA
FBgn0030891	Ada3	transcriptional Adaptor 3	transcriptional Adaptor 3 (Ada3) encodes subunit of some chromatin modifying complexes. [Date last reviewed: 2019-08-01]
FBgn0030892	CG7206	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030893	RhoGAP16F	Rho GTPase activating protein at 16F	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030894	Mvb12	Multivesicular body subunit 12	NA
FBgn0030915	CG6179	NA	NA
FBgn0030925	Hayan	Hayan	Hayan (Hayan) encodes a hemolymphatic serine protease involved in the activation of the melanization cascade. It is thought to directly cleave the prophenoloxidases encoded by PPO1 and/or PPO2. [Date last reviewed: 2019-03-07]
FBgn0030930	Pgant7	Polypeptide N-Acetylgalactosaminyltransferase 7	NA
FBgn0030941	wgn	wengen	wengen (wgn) encodes a receptor for tumor necrosis factor (TNF) ligands, such as the product of egr. Signalling by this receptor is involved in apoptosis, photoreceptor axon guidance and nutritional control of body size. [Date last reviewed: 2019-03-21]
FBgn0030943	Nup35	Nucleoporin 35kDa	NA
FBgn0030944	Hou	Houki	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030945	Ing3	Inhibitor of growth family, member 3	NA
FBgn0030946	CG6659	NA	NA
FBgn0030955	CG6891	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030956	CG18259	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030958	CR6900	NA	NA
FBgn0030959	CG6961	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030960	Atg101	Autophagy-related 101	Autophagy-related 101 (Atg101) encodes a subunit of the evolutionarily conserved Atg1 kinase complex, which controls the initiation of autophagosome formation. [Date last reviewed: 2019-03-07]
FBgn0030963	CG7101	NA	NA
FBgn0030966	shop	shopper	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030968	CG7322	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030969	Usp39	Ubiquitin specific protease 39	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030970	CG7326	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0030973	CG7332	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030974	Flacc	Fl(2)d-associated complex component	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030990	CG7556	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030991	CG7453	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030992	CG33253	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030993	Mec2	Mec2	NA
FBgn0030994	HP1D3csd	Heterochromatin Protein 1D3 chromoshadow domain	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0030995	CG7914	NA	NA
FBgn0030996	CG14194	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0031002	CG14196	NA	NA
FBgn0031003	CG7889	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0031006	rictor	rapamycin-insensitive companion of Tor	rapamycin-insensitive companion of Tor (rictor) encodes an essential component of TOR complex 2 where it controls phosphorylation of protein kinases, such as those encoded by Akt and trc. The product of rictor contributes to the regulation of tissue growth, dendritic tiling, long term memory, tolerance to heat stress, and mitochondrial quality control. [Date last reviewed: 2019-03-14]
FBgn0031008	CG8010	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0031011	CG8034	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0031012	CG8051	NA	NA
FBgn0031016	kek5	kekkon 5	kekkon 5 (kek5) encodes a transmembrane protein involved in BMP signaling regulation. [Date last reviewed: 2019-09-12]
FBgn0031020	Naa15-16	N(alpha)-acetyltransferase 15/16	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0031021	ND-18	NADH dehydrogenase (ubiquinone) 18 kDa subunit	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0031022	CG12204	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-10-13]
FBgn0031023	CG14200	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0031030	Tao	Tao	Tao (Tao) encodes a Ser/Thr kinase belonging to the Mst/Ste20 family. It is implicated in the Hippo and PAR-1 pathways. It contributes to restriction of tissue growth during development, regulation of microtubule dynamics, neuronal polarity, neural development, ethanol-stimulated behavioral response, and apoptosis. [Date last reviewed: 2019-03-14]
FBgn0031031	CG14218	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0031032	CG14204	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0031034	CG14205	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0031036	CG14220	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0031037	CG14207	NA	NA
FBgn0031040	CG14210	NA	NA
FBgn0031042	CG14221	NA	NA
FBgn0031043	Naa20A	N(alpha)-acetyltransferase 20 A	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0031044	MKP-4	MAPK Phosphatase 4	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0031045	CG14212	NA	NA
FBgn0031047	Rcd-1	Required for cell differentiation 1	NA
FBgn0031048	CG12237	NA	NA
FBgn0031049	Sec61gamma	Sec61 gamma subunit	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0031050	Arp10	Actin-related protein 10	Actin-related protein 10 (Arp10) encodes a component of the dynactin multiprotein complex that is involved in microtubule-based movement. [Date last reviewed: 2019-07-11]
FBgn0031051	Ranbp21	Ranbp21	NA
FBgn0031052	Elys	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0031053	CG14223	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-10-13]
FBgn0031054	Ssu72	Ssu72 CTD phosphatase	Ssu72 CTD phosphatase (Ssu72) encodes an RNA polymerase II C-terminal domain (CTD) phosphatase. Its phosphatase activity is important for RNAPII transcription and termination and for gene looping. It may also be involved in the regulation of sister chromatid cohesion. [Date last reviewed: 2019-03-14]
FBgn0031055	et	eye transformer	eye transformer (et) encodes a type 1 cytokine receptor in the JAK/STAT pathway that behaves as a dominant negative receptor. It plays a key role in the larval hematopoietic organ the lymph gland under wasp parasitism. [Date last reviewed: 2019-03-07]
FBgn0031057	Ubqn	Ubiquilin	Ubiquilin (Ubqn) encodes a protein containing an N-terminal ubiquitin-like domain and a C-terminal ubiquitin-associated domain. It binds and delivers ubiquitinated, misfolded or no longer functionally required proteins to the ubiquitin-proteasome system and/or autophagy. [Date last reviewed: 2018-10-04]
FBgn0031058	CG14227	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0031059	CG14229	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0031060	Tcs4	Threonyl-carbamoyl synthesis 4	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0031061	CG14232	NA	NA
FBgn0031062	CG14230	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0031066	COX6B	Cytochrome c oxidase subunit 6B	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0031068	Alr	Augmenter of liver regeneration	NA
FBgn0031069	Abcd3	ATP binding cassette subfamily D member 3	NA
FBgn0031070	CG12702	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0031077	THADA	THADA	THADA (THADA) encodes a metabolic regulator that controls the balance between fat storage and heat production. It physically interacts with the ER calcium pump encoded by SERCA and regulates its activity to control metabolism. [Date last reviewed: 2018-10-04]
FBgn0031078	Nup205	Nucleoporin 205kD	NA
FBgn0031080	CG12655	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-10-13]
FBgn0031089	aspr	asperous	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0031090	Rab35	Rab35	Rab35 (Rab35) encodes a protein that regulates proximal versus distal growth of seamless tubes in the terminal cells of the tracheal system. [Date last reviewed: 2018-10-04]
FBgn0031091	Phf7	PHD finger protein 7	NA
FBgn0031092	Ech1	Enoyl-CoA hydratase 1	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0031093	CG9581	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0031094	CG9578	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0031097	obst-A	obstructor-A	obstructor-A (obst-A) encodes a protein that forms a core complex with chitin and the chitin modifying proteins encoded by serp and knk. This complex is required for assembly, maturation and preservation of the chitinous cuticles at the end of embryogenesis and probably throughout larval development. [Date last reviewed: 2019-03-14]
FBgn0031098	CG17068	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0031099	CG17065	NA	NA
FBgn0031106	Syx16	Syntaxin 16	Syntaxin 16 (Syx16) encodes a member of the soluble N-ethylmaleimide sensitive factor attachment protein receptor (SNARE) family. It is localized to late Golgi compartments and is part of a trans-SNARE complex responsible for endosome-to-Golgi/trans Golgi network retrograde transport. [Date last reviewed: 2018-10-04]
FBgn0031107	HERC2	HECT and RLD domain containing protein 2	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0031114	cactin	cactin	cactin (cactin) encodes a conserved protein that functions in the Rel-NFkB pathway, possibly by controlling the stability of the product of cact. [Date last reviewed: 2018-10-04]
FBgn0031115	CG11710	NA	NA
FBgn0031117	GstT3	Glutathione S transferase T3	Glutathione S transferase T3 (GstT3) encodes an enzyme involved in glutathione metabolic processes. [Date last reviewed: 2019-06-27]
FBgn0031118	RhoGAP19D	Rho GTPase activating protein at 19D	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0031119	CG1812	NA	NA
FBgn0031126	Cyp6v1	Cytochrome P450 6v1	NA
FBgn0031142	r-cup	ryder cup	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0031143	CG1532	NA	NA
FBgn0031144	CG1529	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0031145	Ntf-2	Nuclear transport factor-2	Nuclear transport factor-2 (Ntf-2) is an essential gene regulating nuclear import. It encodes a protein that binds to the nuclear pore protein encoded by DCTN4-p62 and to the product of Ran and regulates the nuclear import of nuclear localization signal containing proteins. [Date last reviewed: 2019-03-14]
FBgn0031148	Cbs	Cystathionine beta-synthase	Cystathionine β-synthase (Cbs) encodes an enzyme involved in endoplasmic reticulum stress response. [Date last reviewed: 2019-09-12]
FBgn0031149	Stt3A	Catalytic subunit 3A of the oligosaccharyltransferase complex	NA
FBgn0031150	bves	bves	NA
FBgn0031157	CG1503	NA	NA
FBgn0031161	CG15445	NA	NA
FBgn0031169	CG1494	NA	NA
FBgn0031170	Abca3	ATP binding cassette subfamily A member 3	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0031174	CG1486	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0031183	CG14621	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0031184	CG14615	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0031187	Usp2	Ubiquitin specific protease 2	NA
FBgn0031188	CG14613	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0031189	CG14618	NA	NA
FBgn0031190	CG12576	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0031191	Cp110	Centriolar coiled coil protein 110kDa	Centriolar coiled coil protein 110kDa (Cp110) encodes a centriolar protein that localizes to the distal end of both mother and daughter centrioles. It seems to prevent the centriole microtubules from extending beyond the distal end of the centriole. It interacts with the product of Cep97, another protein localized to the distal end of the centrioles. [Date last reviewed: 2019-03-07]
FBgn0031194	CG17598	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0031195	CG17600	NA	NA
FBgn0031201	CG12446	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-10-13]
FBgn0031213	galectin	galectin	galectin (galectin) encodes a galactoside binding protein involved in synaptic target recognition. [Date last reviewed: 2019-09-12]
FBgn0031216	Zir	Zizimin-related	Zizimin-related (Zir) encodes a Rho guanine nucleotide exchange factor involved in the cellular immune response. [Date last reviewed: 2019-07-11]
FBgn0031217	CG11377	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0031219	CG13694	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0031220	CG4822	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0031224	CG11454	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0031227	CG3709	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0031228	ND-15	NADH dehydrogenase (ubiquinone) 15 kDa subunit	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0031229	CG3436	NA	NA
FBgn0031231	mRpL10	mitochondrial ribosomal protein L10	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0031233	Tbc1d15-17	TBC1 domain family member 15/17	NA
FBgn0031238	CG3645	NA	NA
FBgn0031244	CG11601	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0031245	CG3625	NA	NA
FBgn0031247	CG11562	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0031250	Ent1	Equilibrative nucleoside transporter 1	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0031252	CG13690	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0031253	CG11885	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0031254	CG13692	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0031256	shv	shriveled	shriveled (shv) encodes a secreted protein that activates integrin signaling. It is involved in synapse maturation regulation and stem cell maintenance. [Date last reviewed: 2019-09-12]
FBgn0031257	CG4133	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0031258	CG4297	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0031260	Spp	Signal peptide peptidase	NA
FBgn0031261	nAChRbeta3	nicotinic Acetylcholine Receptor beta3	NA
FBgn0031263	Tspo	Translocator protein	Translocator protein (Tspo) encodes a protein localized in the outer mitochondrial membrane that is thought to be involved in various pathways, including steroid and heme biosynthesis, apoptosis, protein import, cell proliferation and differentiation and also has been proposed to participate in the formation of the mitochondrial permeability transition pore. [Date last reviewed: 2019-03-14]
FBgn0031265	CG2794	NA	NA
FBgn0031266	Sf3b1	Splicing factor 3b subunit 1	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0031267	Ipk2	Ipk2	Ipk2 (Ipk2) encodes a kinase involved in imaginal disc development and biosynthesis of inositol phosphate. [Date last reviewed: 2019-09-12]
FBgn0031268	cold	coiled	coiled (cold) encodes a membrane glycoprotein of the Ly6 family that is required for the formation of septate junctions in both epithelial tissues and in sub-perineural glial cells. [Date last reviewed: 2018-10-04]
FBgn0031281	Saf6	SAGA factor-like TAF6	SAGA factor-like TAF6 (Saf6) encodes a component of the Spt-Ada-Gcn5 Acetyltransferase (SAGA) chromatin modifying complex. This complex is responsible for acetylation of histones and deubiquitination of the product of His2B at active promoters. The product of Saf6 replaces the product of mia within SAGA when the product of mia is restricted to the TFIID transcription complex. Notably, the product of Saf6 is essential for SAGA's co-activator function but does not impact either of its enzymatic activities. [Date last reviewed: 2019-03-14]
FBgn0031282	Pex12	Peroxin 12	Peroxin 12 (Pex12) encodes a peroxisome protein important for sperm development. [Date last reviewed: 2019-03-14]
FBgn0031284	PGAP2	Post-GPI attachment to proteins 2	NA
FBgn0031285	CG3662	NA	NA
FBgn0031286	CG3862	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0031287	CG4291	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0031298	Atg4a	Autophagy-related 4a	Autophagy-related 4a (Atg4a) encodes a protein involved in autophagy. [Date last reviewed: 2019-06-27]
FBgn0031299	CG4629	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0031302	CG14340	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0031304	TBC1D23	TBC1 domain family member 23	NA
FBgn0031307	MFS3	Major Facilitator Superfamily Transporter 3	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0031309	Tfb4	Transcription factor B4	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0031310	Vps29	Vacuolar protein sorting 29	Vacuolar protein sorting 29 (Vps29) encodes a subunit of the retromer complex involved in cargo recognition and recycling from endosomes to the trans-Golgi network or plasma membrane. [Date last reviewed: 2019-03-21]
FBgn0031312	Tango14	Transport and Golgi organization 14	NA
FBgn0031313	CG5080	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0031314	IntS14	Integrator 14	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0031315	CG14341	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0031317	Charon	Charon	Charon (Charon) encodes a nuclear chromatin associated protein that controls Rel-dependent innate immune response and functions as a regulator of antibacterial and antifungal immune defense. It mediates Parp-dependent transcriptional responses downstream of the innate immune pathway. [Date last reviewed: 2018-10-04]
FBgn0031318	CG4887	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0031319	CG4896	NA	NA
FBgn0031320	CG5126	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0031321	Tgt	tRNA-guanine transglycosylase	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0031322	CG5001	NA	NA
FBgn0031327	CG5397	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0031344	CG7420	NA	NA
FBgn0031351	CG14352	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-10-13]
FBgn0031356	CG17660	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0031357	mRpL48	mitochondrial ribosomal protein L48	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0031359	Rim2	Replication in mitochondria 2	Replication in mitochondria 2 (Rim2) encodes a mitochondrial carrier involved in the transport of deoxynucleotides and is essential to maintain mtDNA maintenance and replication. [Date last reviewed: 2018-10-04]
FBgn0031360	CG31937	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0031361	CG17652	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0031374	Wdr62	WD repeat domain 62	WD repeat domain 62 (Wdr62) encodes a protein involved in mitosis regulation. [Date last reviewed: 2019-09-19]
FBgn0031377	CG15356	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0031378	CG15362	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0031379	CG7289	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0031381	Npc2a	Niemann-Pick type C-2a	Niemann-Pick type C-2a (Npc2a) encodes a protein involved in regulating sterol homeostasis and hydroxyecdysone biosynthesis. It also plays a role in the immune signaling via interaction with bacterial lipopolysaccharides, lipid A, peptidoglycan and lipoteichoic acid. [Date last reviewed: 2021-01-21]
FBgn0031384	CG4238	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0031389	CG4259	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0031390	tho2	tho2	tho2 (tho2) encodes a component of the THO complex that plays an essential role in nuclear export of mRNAs. [Date last reviewed: 2018-10-04]
FBgn0031391	CG11723	NA	NA
FBgn0031392	AIF	Apoptosis inducing factor	Apoptosis inducing factor (AIF) encodes a phylogenetically conserved redox-active flavoprotein that contributes to cell death and oxidative phosphorylation in mitochondria. [Date last reviewed: 2019-03-07]
FBgn0031395	CG10874	NA	NA
FBgn0031398	daed	daedalus	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0031399	mio	missing oocyte	missing oocyte (mio) encodes a component of the GAP Activity Towards Rags 2 (GATOR2) complex, which promotes the activation of the product of Tor and anabolic metabolism. It localizes to lysosomes and autolysosmes and regulates lysosome function independent of the activity of the product of Tor. It is required for the maintenance of the meiotic cycle. [Date last reviewed: 2019-03-14]
FBgn0031401	papi	papi	NA
FBgn0031403	CG15387	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0031413	CG9967	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0031414	eys	eyes shut	NA
FBgn0031418	CG3609	NA	NA
FBgn0031420	Atxn7	Ataxin 7	Ataxin 7 (Atxn7) encodes a component of the SAGA chromatin modifying complex, which is responsible for acetylation of histones and deubiquitination of the product of His2B at active promoters. The product of Atxn7 anchors the non-stop containing deubiquitinase module to the remainder of SAGA. Atxn7 is an essential gene for larval survival, neural development, and maintenance of neural tissues. [Date last reviewed: 2019-03-07]
FBgn0031422	PIG-Wa	Phosphatidylinositol glycan anchor biosynthesis class W a	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0031428	CG9886	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0031435	Elba2	Early boundary activity 2	Early boundary activity 2 (Elba2) encodes a chromatin boundary factor involved in the regulation of chromatin silencing. [Date last reviewed: 2019-09-12]
FBgn0031436	ND-B17.2	NADH dehydrogenase (ubiquinone) B17.2 subunit	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0031437	Arpc5	Actin-related protein 2/3 complex, subunit 5	Actin-related protein 2/3 complex, subunit 5 (Arpc5) encodes one of seven components of the highly conserved Arp2/3 complex. The Arp2/3 complex is required for many cellular and developmental processes requiring F-actin polymerization, including germline ring canal growth, embryonic cellularization, myoblast fusion, and endocytosis. [Date last reviewed: 2019-03-07]
FBgn0031449	CG31689	NA	NA
FBgn0031450	Hrs	Hepatocyte growth factor regulated tyrosine kinase substrate	Hepatocyte growth factor regulated tyrosine kinase substrate (Hrs) encodes a protein that, together with the product encoded by Stam, forms the ESCRT-0 complex. This complex is responsible for the initial selection of ubiquitinated proteins that are ultimately degraded in lysosomes. [Date last reviewed: 2018-10-04]
FBgn0031452	Cwc25	Cwc25	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0031453	Bacc	Bacchus	Bacchus (Bacc) encodes a tyramine-dependent nuclear regulator involved in ethanol sensitivity. [Date last reviewed: 2019-09-19]
FBgn0031456	Tnpo-SR	Transportin-Serine/Arginine rich	Transportin-Serine/Arginine rich (Tnpo-SR) encodes a importin-beta family protein involved in the regulation of mRNA splicing. It contributes to the import into the nucleus of serine/arginine-rich (SR) proteins, which are involved in mRNA splicing. [Date last reviewed: 2019-09-12]
FBgn0031457	Snx21	Sorting nexin 21	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0031458	aph-1	anterior pharynx defective 1	anterior pharynx defective 1 (aph-1) encodes a scaffolding subunit of the gamma-secretase complex together with the products of Psn, Nct and pen-2. It is involved in several Notch related processes such as differentiation, cellular organization and developmental patterning via gamma-secretase proteolitic function. [Date last reviewed: 2018-10-04]
FBgn0031459	HINT1	histidine triad nucleotide binding protein 1	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0031460	CG15399	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0031461	daw	dawdle	dawdle (daw) encodes an Activin- like ligand of the TGF beta superfamily that is required for proper tricarboxylic acid cycle function in the fat body and also regulates insulin release from IPC neurons. [Date last reviewed: 2019-03-07]
FBgn0031470	CG18557	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0031474	CG2991	NA	NA
FBgn0031478	CG8814	NA	NA
FBgn0031479	Prx6005	Peroxiredoxin 6005	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0031483	CG9641	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-10-13]
FBgn0031484	CG3165	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0031485	CG9643	NA	NA
FBgn0031488	Ccdc85	NA	NA
FBgn0031489	CG17224	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0031490	CG17264	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0031491	alpha4GT1	alpha1,4-galactosyltransferase 1	NA
FBgn0031492	Prp40	pre-mRNA processing factor 40	NA
FBgn0031493	Sf3b2	Splicing factor 3b subunit 2	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0031494	CG17219	NA	NA
FBgn0031495	GABPI	beta4GalNAcTB pilot	β4GalNAcTB pilot (GABPI) encodes a Golgi multitransmembrane protein of the DHHC family. In contrast to other members of the DHHC family, it lacks palmitoylation activity. It is required for Golgi localization and for the activity of the glycosphingolipid specific glycosyltransferase encoded by β4GalNAcTB. [Date last reviewed: 2019-03-07]
FBgn0031497	SerRS	Seryl-tRNA synthetase	Seryl-tRNA synthetase (SerRS) encodes a protein that aminoacylates transfer RNAs (tRNA) for their use by the ribosome during protein synthesis. [Date last reviewed: 2019-08-01]
FBgn0031498	CG17260	NA	NA
FBgn0031500	CG17221	NA	NA
FBgn0031505	ND-B14.5B	NADH dehydrogenase (ubiquinone) B14.5 B subunit	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0031516	CG9663	NA	NA
FBgn0031519	Fign	Fidgetin	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0031529	CG9662	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0031530	Pgant2	Polypeptide N-Acetylgalactosaminyltransferase 2	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0031534	Snx1	Sorting nexin 1	NA
FBgn0031535	CG12795	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0031536	Cog3	Component of oligomeric golgi complex 3	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0031538	CG3246	NA	NA
FBgn0031540	Pif1	Pif1 DNA helicase	NA
FBgn0031544	CG17593	NA	NA
FBgn0031547	Sr-CIV	Scavenger receptor class C, type IV	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0031548	CG8852	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-10-13]
FBgn0031549	Spindly	Spindly	Spindly (Spindly) encodes a key regulator of dynein recruitment to kinetochores and is involved in the spindle assembly checkpoint during the cell cycle. It also contributes to cell morphology and migration. [Date last reviewed: 2018-11-15]
FBgn0031566	CG2818	NA	NA
FBgn0031568	CG10019	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0031571	bark	bark beetle	bark beetle (bark) encodes a putative transmembrane scavenger receptor-like protein that is essential for the maturation of septate junctions (SJ). Loss of bark produces cell adhesion defects and mislocalization of SJ core complexes. [Date last reviewed: 2019-03-07]
FBgn0031573	CG3407	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0031574	TTLL4B	Tubulin tyrosine ligase-like 4B	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0031575	Cep97	Centrosomal protein 97kDa	Centrosomal protein 97kDa (Cep97) encodes a centriolar protein that localizes to the distal end of both mother and daughter centrioles. It interacts with the product of Cp110, which is also localized to the distal end of the centrioles. Together they seem to prevent the centriole microtubules from extending beyond the distal end of the centriole. [Date last reviewed: 2019-03-07]
FBgn0031589	Naprt	Nicotinate phosphoribosyltransferase	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0031590	CG3702	NA	NA
FBgn0031597	CG17612	NA	NA
FBgn0031598	Vps53	Vacuolar protein sorting 53	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0031600	CG3652	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0031601	Dim1	Dim1	NA
FBgn0031603	CG15432	NA	NA
FBgn0031604	Elp3	Elongator complex protein 3	Elongator complex protein 3 (Elp3) encodes a Lysine (K) acetyltransferase (KAT) that resides primarily in the cytoplasm of neurons. It acetylates the product of brp in an opposite reaction to the product of HDAC6 to regulate T-bar morphology and function, and unlike most KATs it does not acetylate histones. [Date last reviewed: 2019-03-07]
FBgn0031606	CG15439	NA	NA
FBgn0031607	Secp43	tRNA Selenocysteine associated protein	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0031608	CG15435	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0031609	CG15443	NA	NA
FBgn0031610	Paris	Parkin Interacting Substrate	NA
FBgn0031611	FIG4	FIG4 phosphoinositide 5-phosphatase	NA
FBgn0031628	CG3294	NA	NA
FBgn0031631	CG3225	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0031633	Fnta	Farnesyl transferase alpha subunit	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0031635	tank	tank	tank (tank) encodes the homolog of tumor suppressor EI24/PIG8. It regulates ethanol sedation sensitivity. [Date last reviewed: 2019-03-14]
FBgn0031637	mxt	mextli	mextli (mxt) encodes a protein that promotes translation. It binds to the products of eIF4E1 and eIF3h. It contributes to maintenance of germline stem cells and it is also involved in early embryogenesis. [Date last reviewed: 2019-03-14]
FBgn0031638	CG11927	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0031639	mRpS2	mitochondrial ribosomal protein S2	NA
FBgn0031640	Mon1	Monensin sensitivity 1	Monensin sensitivity 1 (Mon1) encodes a protein that forms a complex with the product of Ccz1 and acts as an exchange factor of the small G-protein encoded by Rab7. It activates and recruits the product of Rab7 to the maturing endosome, inducing the fusion of the matured endosome with the lysosome. Mon1/Ccz1 complex loss of function results in Rab7 phenotypes. [Date last reviewed: 2019-03-14]
FBgn0031643	CG3008	NA	NA
FBgn0031644	CG15625	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0031645	CG3036	NA	NA
FBgn0031651	mRpL24	mitochondrial ribosomal protein L24	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0031652	jet	jetlag	jetlag (jet) encodes an F-box protein that is a component of an SCF E3 ubiquitin ligase complex. It targets the product of tim for degradation upon light exposure, and is essential for photic entrainment of the circadian clock. [Date last reviewed: 2019-03-07]
FBgn0031655	Marcal1	Marcal1	Marcal1 (Marcal1) encodes an ATP-dependent DNA annealing helicase that recognizes single-stranded to double-stranded DNA transitions. It maintains genomic integrity through its roles in DNA repair, DNA replication, DNA recombination and gene expression. [Date last reviewed: 2019-03-14]
FBgn0031657	Polr1C	RNA polymerase I and III subunit C	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0031659	CG14043	NA	NA
FBgn0031660	mRpL28	mitochondrial ribosomal protein L28	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0031661	Gmd	GDP-mannose 4,6-dehydratase	NA
FBgn0031662	CG3792	NA	NA
FBgn0031663	CG8891	NA	NA
FBgn0031664	CG8892	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0031670	SelT	Selenoprotein T	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0031673	CG31650	NA	NA
FBgn0031675	CG9121	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0031676	senju	senju	NA
FBgn0031677	CG14036	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0031678	Nepl3	Neprilysin-like 3	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0031681	Pgant5	Polypeptide N-Acetylgalactosaminyltransferase 5	Polypeptide N-Acetylgalactosaminyltransferase 5 (Pgant5) encodes a member of the UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase family and catalyzes the transfer of a GalNAc sugar onto the hydroxyl groups of serine and threonine in secreted or membrane-bound proteins. The product of Pgant5 is essential and affects digestive system acidification. [Date last reviewed: 2019-03-14]
FBgn0031682	CG5828	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0031683	CG4230	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0031684	ND-13A	NADH dehydrogenase (ubiquinone) 13 kDa A subunit	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0031689	Cyp28d1	Cytochrome P450 28d1	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0031693	Cyp4ac1	Cytochrome P450 4ac1	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0031696	Bub1	Bub1 kinase	Bub1 kinase (Bub1) encodes a spindle checkpoint protein regulating chromosome congression. It also contributes to clathrin-dependent endocytosis of pathogens. [Date last reviewed: 2019-06-13]
FBgn0031698	Ncoa6	Nuclear receptor coactivator 6	Nuclear receptor coactivator 6 (Ncoa6) encodes a subunit of the Trithorax-related (Trr) complex, a COMPASS-like complex that mediates the methylation of histone H3K4. The product of Ncoa6 is required for transcriptional output of the Hippo pathway by directly interacting with the protein encoded by yki and recruiting the Trr complex to Hippo target genes. [Date last reviewed: 2018-11-15]
FBgn0031703	Acsf2	Acyl-CoA synthetase family member 2	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0031708	CG7382	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0031710	Vps52	Vacuolar protein sorting 52	NA
FBgn0031711	CG6907	NA	NA
FBgn0031713	Coq6	Coenzyme Q6	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0031717	Oscillin	Oscillin	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0031736	CG11030	NA	NA
FBgn0031738	CG9171	NA	NA
FBgn0031739	CG14005	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0031740	CG7239	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0031752	CG9044	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0031759	Kdm5	Lysine demethylase 5	Lysine demethylase 5 (Kdm5) encodes a trimethyl H3K4 histone demethylase that regulates transcription through both demethylase-dependent and demethylase-independent mechanisms. It has roles in regulating cell growth, circadian rhythm, stress resistance, hematopoiesis and fertility. [Date last reviewed: 2019-03-14]
FBgn0031760	Tsp26A	Tetraspanin 26A	Tetraspanin 26A (Tsp26A) encodes a member of the tetraspanin superfamily. With two other tetraspanins, encoded by Tsp3A and Tsp86D, it regulates the trafficking of the product of kuz and consequently Notch signaling and several Notch-dependent developmental processes. [Date last reviewed: 2019-03-14]
FBgn0031762	CG9098	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0031764	CG9107	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0031768	IPIP	Inositol phosphatase interacting protein	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0031769	CG9135	NA	NA
FBgn0031771	ND-51	NADH dehydrogenase (ubiquinone) 51 kDa subunit	NADH dehydrogenase (ubiquinone) 51 kDa subunit (ND-51) encodes a flavoprotein and iron-sulfur-containing oxidoreductase that catalyzes the oxidation of NADH to NAD. It is a component of the mitochondrial electron transport complex I, which is part of the oxidative phosphorylation pathway. It may have a role in regulating aggression behavior. [Date last reviewed: 2019-09-26]
FBgn0031772	CG13994	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0031773	Fbw5	F-box and WD repeat domain containing 5	F-box and WD repeat domain containing 5 (Fbw5) encodes a protein that targets proteins for destruction via its role as a substrate receptor for the CRL4 E3 ubiquitin ligase. A key target of the product of Fbw5 is the subunit of the tuberous sclerosis complex encoded by gig, an important negative regulator of cellular growth via inhibition of the TOR kinase pathway. [Date last reviewed: 2019-03-07]
FBgn0031774	CG9147	NA	NA
FBgn0031776	Pfdn1	Prefoldin 1	NA
FBgn0031777	CG9154	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0031779	CG9175	NA	NA
FBgn0031782	WDR79	WD repeat domain 79	WD repeat domain 79 (WDR79) encodes a protein that binds to the CAB box of the Small Cajal body-specific RNAs (scaRNAs). It is a component of the nuclear Cajal body (CB) and is required for CB formation. [Date last reviewed: 2019-09-26]
FBgn0031799	Pez	Pez	Pez (Pez) encodes an adaptor protein that is degraded via the product of Su(dx). It contributes to stem cell proliferation by regulating Hippo signalling. It interacts with the product of kibra and restricts the product of yki activity. [Date last reviewed: 2019-03-14]
FBgn0031805	Nepl4	Neprilysin-like 4	NA
FBgn0031811	CG13982	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0031813	Acox3	Acyl-CoA oxidase 3	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0031814	retm	real-time	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0031815	frj	farjavit	farjavit (frj) encodes a lysophospholipid acyltransferase that preferentially adds arachidonic acid to lysophosphatidylinositol. [Date last reviewed: 2019-03-07]
FBgn0031816	Rchy1	Ring finger and CHY zinc finger domain containing 1	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0031817	HemK1	HemK methyltransferase 1	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0031818	CG9536	NA	NA
FBgn0031822	Phf5a	PHD finger protein 5a	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0031824	CG9547	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0031830	COX5B	Cytochrome c oxidase subunit 5B	NA
FBgn0031832	CG9596	NA	NA
FBgn0031834	CG13766	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0031836	CG11050	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0031844	CG13771	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0031848	Nse1	Non-SMC element 1	Non-SMC element 1 (Nse1) encodes a RING finger protein with E3 ubiquitin ligase activity that is part of the SMC5/6 protein complex. This complex is critical to genome stability, and is required for homologous DNA recombination-based processes. [Date last reviewed: 2018-11-15]
FBgn0031851	Aatf	Apoptosis antagonizing transcription factor	Apoptosis antagonizing transcription factor (Aatf) encodes a transcription factor that is a target of the kinases encoded by tefu and lok. It is involved in the control of the cell cycle, DNA damage response, and regulation of apoptosis. [Date last reviewed: 2018-11-15]
FBgn0031868	Rat1	Rat1 5'-3' exoribonuclease	Rat1 5'-3' exoribonuclease (Rat1) encodes a member of the 5'-3' exonuclease family. It is required for mRNA processing and mutations cause phenotypes in various cell types, including the nervous system. [Date last reviewed: 2019-03-14]
FBgn0031871	Fgop2	Fibroblast growth factor receptor 1 oncogene partner 2	NA
FBgn0031872	ihog	interference hedgehog	interference hedgehog (ihog) encodes a type 1 membrane protein that acts as a co-receptor for the product of hh upstream or at the level of the receptor encoded by ptc. It interacts with the products of disp, dlp, dally and shf. It is involved in imaginal pattern formation and embryonic cuticle pattern formation. [Date last reviewed: 2018-11-15]
FBgn0031873	Gas41	Gas41	Gas41 (Gas41) encodes a protein that contributes to histone acetylation and is involved in chromatin organization and RNA interference. [Date last reviewed: 2019-08-01]
FBgn0031874	CG13775	NA	NA
FBgn0031875	CG3430	NA	NA
FBgn0031876	Atac1	Ada2a-containing complex component 1	Ada2a-containing complex component 1 (Atac1) encodes a protein involved in chromatin remodeling and histone acetylation. [Date last reviewed: 2019-06-27]
FBgn0031877	Hmgcl	3-Hydroxymethyl-3-methylglutaryl-CoA lyase	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0031878	sip2	septin interacting protein 2	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0031881	MME1	Mitochondrial Magnesium Exporter 1	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0031882	Rab30	Rab30	Rab30 (Rab30) encodes a JNK transcriptional target. It is involved in JNK-mediated processes such as dorsal closure, embryonic head involution and thorax closure. [Date last reviewed: 2019-08-01]
FBgn0031883	Caper	Caper	Caper (Caper) encodes an RNA-binding protein involved in regulation of alternative mRNA splicing. [Date last reviewed: 2019-09-19]
FBgn0031885	Mnn1	Menin 1	Menin 1 (Mnn1) encodes a protein that regulates the response of several stresses including hypoxia, hyperosmolarity, heat shock, and oxidative stress. It is important during the mitotic G1 DNA damage checkpoint in a process mediated by the product of CHES-1-like. [Date last reviewed: 2019-03-14]
FBgn0031886	Nuf2	Nuf2	Nuf2 (Nuf2) encodes a protein involved in mitotic metaphase plate congression. [Date last reviewed: 2019-09-26]
FBgn0031888	Pvf2	PDGF- and VEGF-related factor 2	PDGF- and VEGF-related factor 2 (Pvf2) encodes a ligand for the receptor tyrosine kinase enocded by Pvr. It has roles in embryonic plasmatocyte survival and migration, and in the proliferation of adult midgut intestinal stem cells. [Date last reviewed: 2019-03-14]
FBgn0031893	MICU1	Mitochondrial calcium uptake 1	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0031894	CG4496	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0031895	CG4497	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0031896	CG4502	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0031897	CG13784	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0031904	CG5149	NA	NA
FBgn0031909	CG5181	NA	NA
FBgn0031913	CG5958	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0031914	CG5973	NA	NA
FBgn0031937	CG13795	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0031947	Brd7-9	Bromodomain containing 7/9	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0031948	CG7149	NA	NA
FBgn0031950	Herp	Homocysteine-induced endoplasmic reticulum protein	NA
FBgn0031951	r2d2	r2d2	r2d2 (r2d2) encodes a double-stranded RNA-binding protein. It interacts with the product of Dcr-2 to form the core of RISC loading complex, which recruits duplex siRNA to the RISC. [Date last reviewed: 2019-03-14]
FBgn0031952	cdc14	cell division cycle 14	NA
FBgn0031968	CG7231	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0031969	pes	peste	NA
FBgn0031971	Sirup	Starvation-upregulated protein	Starvation-upregulated protein (Sirup) encodes a critical assembly factor for Complex II in the electron transport chain of mitochondria. Loss of Sirup results in motility defects, neurodegeneration, and oxidative stress. [Date last reviewed: 2019-03-14]
FBgn0031972	Wwox	WW domain containing oxidoreductase	WW domain containing oxidoreductase (Wwox) encodes a protein that contributes to homeostasis by regulating the balance between oxidative phosphorylation and glycolysis. It modulates the cell death mediated by the product of egr, which is accompanied by an increase in levels of reactive oxygen species. [Date last reviewed: 2018-11-15]
FBgn0031973	Spn28Dc	Serpin 28Dc	Serpin 28Dc (Spn28Dc) encodes a hemolymphatic Serpin that negatively regulates an uncharacterized serine protease in the melanization cascade. [Date last reviewed: 2019-03-14]
FBgn0031974	CG12560	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0031977	baf	barrier to autointegration factor	NA
FBgn0031979	CCDC53	Coiled-coil domain containing 53	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0031980	RpL36A	Ribosomal protein L36A	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0031981	Megf8	Multiple EGF like domains 8	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0031985	mon2	monensin sensitivity 2	NA
FBgn0031987	CG12375	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0031988	CG8668	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0031990	PAPLA1	Phosphatidic Acid Phospholipase A1	Phosphatidic Acid Phospholipase A1 (PAPLA1) encodes a protein required for the endoplasmic reticulum to Golgi trafficking of a family of G-protein coupled receptors. [Date last reviewed: 2019-03-14]
FBgn0031992	Acbp1	Acyl-CoA binding protein 1	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0031995	CG8475	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0031996	CG8460	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0031997	PGAP5	Post-GPI attachment to proteins 5	Post-GPI attachment to proteins 5 (PGAP5) encodes a protein that belongs to a dimetal-containing phosphoesterase family and catalyzes the remodeling of the glycan moiety on glycosylphosphatidylinositol (GPI)-anchored proteins. Its catalytic activity is a prerequisite for the efficient exit of GPI-anchor proteins from the ER. [Date last reviewed: 2019-03-14]
FBgn0031998	SLC5A11	Sodium/solute co-transporter-like 5A11	Sodium/solute co-transporter-like 5A11 (SLC5A11) encodes a protein involved in behavioral response to nutrient. [Date last reviewed: 2019-03-14]
FBgn0031999	CG8419	NA	NA
FBgn0032000	CG8372	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0032001	CG8360	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032002	CG8353	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032004	CG8292	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-10-13]
FBgn0032005	Snx6	Sorting nexin 6	NA
FBgn0032006	Pvr	PDGF- and VEGF-receptor related	PDGF- and VEGF-receptor related (Pvr) encodes a receptor tyrosine kinase activated by the binding of PDGF- and VEGF-related factors (encoded by Pvf1, Pvf2 or Pvf3). It is involved in cell migration regulation and it has been shown to activate the canonical Ras/Raf/MAP kinase (ERK) cascade, the PI3K kinase pathway, TORC1, Rho family small GTPases and the JNK cascade, in a context-dependent manner. [Date last reviewed: 2019-09-12]
FBgn0032013	Scgalpha	Sarcoglycan alpha	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032014	CG7840	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032015	Ostgamma	Oligosaccharide transferase gamma subunit	Oligosaccharide transferase γ subunit (Ostγ) encodes a subunit of the oligosaccharyltransferase complex involved in cell migration and cellular encapsulation response. [Date last reviewed: 2019-09-19]
FBgn0032016	Mettl14	Methyltransferase like 14	NA
FBgn0032017	CG7810	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032018	CG7806	NA	NA
FBgn0032020	strat	stratum	stratum (strat) encodes an ortholog of the human guanine nucleotide exchange factor RABIF. Together with the product of Rab8, it regulates proper secretion of basement membrane proteins on the basal side of epithelial cells. [Date last reviewed: 2018-11-15]
FBgn0032024	CG14273	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032025	CG7778	NA	NA
FBgn0032026	CG7627	NA	NA
FBgn0032029	CG17292	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032030	Wdr82	WD repeat domain 82	WD repeat domain 82 (Wdr82) encodes a component of the Compass complex, which performs K4 methylation of the histone encoded by His3. [Date last reviewed: 2019-03-21]
FBgn0032031	CG13390	NA	NA
FBgn0032032	CG17294	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032033	CG13392	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-10-13]
FBgn0032034	Rcd4	Reduction in Cnn dots 4	Reduction in Cnn dots 4 (Rcd4) encodes a protein involved in the regulation of the number of centrosomes per cell. [Date last reviewed: 2019-03-14]
FBgn0032036	CG13384	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032040	CG13386	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032042	CG13398	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032047	CG13088	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032050	CG13096	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032051	CG13097	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032052	PIG-U	Phosphatidylinositol glycan anchor biosynthesis class U	Phosphatidylinositol glycan anchor biosynthesis class U (PIG-U) encodes a subunit of glycosylphosphatidylinositol (GPI) transamidase, which mediates GPI anchoring in the endoplasmic reticulum. GPI anchor attachment serves as a general mechanism for linking proteins to the cell surface membrane. [Date last reviewed: 2019-03-14]
FBgn0032053	mRpL51	mitochondrial ribosomal protein L51	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032054	Uba4	Ubiquitin-like activating enzyme 4	Ubiquitin-like activating enzyme 4 (Uba4) encodes a protein involved in molybdopterin cofactor synthesis and protein urmylation. [Date last reviewed: 2019-09-26]
FBgn0032059	PrBP	Prenyl-binding protein	NA
FBgn0032078	C1GalTA	Core 1 Galactosyltransferase A	Core 1 Galactosyltransferase A (C1GalTA) encodes a protein that exhibits strong core 1β1,3GalT activity, and is involved in the synthesis of T antigen in hemocytes. Its roles include hematopoietic stem cell maintenance, neural network and neuromuscular junction formation. [Date last reviewed: 2019-03-07]
FBgn0032079	CG31886	NA	CG31886 encodes a protein that regulates ethanol sedation sensitivity. [Date last reviewed: 2019-03-07]
FBgn0032082	CG18088	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032101	CG9586	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032105	borr	borealin-related	borealin-related (borr) encodes one of the three targeting subunits for the product of aurB in the chromosomal passenger complex. It helps to target the complex to the centromere region of chromosomes and the cleavage furrow during cytokinesis. At centromeres the complex is involved both in pausing mitotic progression when there are chromosome mis-attachments and in correcting those mis-attachments. At the cleavage furrow, the complex is involved in regulating the process of abscission (cell separation). [Date last reviewed: 2019-03-07]
FBgn0032117	FucTB	alpha1,3-fucosyltransferase B	NA
FBgn0032120	CG33298	NA	NA
FBgn0032123	Oatp30B	Organic anion transporting polypeptide 30B	Organic anion transporting polypeptide 30B (Oatp30B) encodes a transmembrane transporter involved in the transport of the cardiac glycoside ouabain. [Date last reviewed: 2019-08-01]
FBgn0032130	brwl	brickwall	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032135	GlcAT-S	Glucuronyltransferase S	NA
FBgn0032136	Apoltp	Apolipoprotein lipid transfer particle	Apolipoprotein lipid transfer particle (Apoltp) encodes a apolipoprotein of the ApoB family. It is assembled with lipids to form high density, low abundance lipoproteins named lipid transfer particles (LTP). LTP catalyzes the transfer of lipids from the gut to circulating lipophorin and from lipophorin to peripheral tissues, such as imaginal discs and ovaries. [Date last reviewed: 2019-03-07]
FBgn0032138	CG4364	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032139	CG13116	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032140	CG13117	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032147	IP3K1	Inositol 1,4,5-triphosphate kinase 1	Inositol 1,4,5-triphosphate kinase 1 (IP3K1) encodes a protein involved in response to oxidative stress. [Date last reviewed: 2019-09-12]
FBgn0032149	CG4036	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032150	CG13123	NA	NA
FBgn0032154	mtDNA-helicase	mitochondrial DNA helicase	mitochondrial DNA helicase (mtDNA-helicase) encodes the replicative mitochondrial DNA helicase, which is responsible for NTPase-dependent double-stranded DNA unwinding during mitochondrial DNA replication. It has roles in mitochondrial genome maintenance, and mitochondrial function. [Date last reviewed: 2018-11-15]
FBgn0032156	CG13124	NA	NA
FBgn0032157	Etl1	Etl1	Etl1 (Etl1) encodes a protein belonging to the Etl1 subfamily of the Snf2 family of helicase-related proteins. It mediates nucleosomal H2A acetylation in an ATP-dependent fashion via the product of nej, resulting in transcriptional regulation. [Date last reviewed: 2018-11-15]
FBgn0032160	CG4598	NA	NA
FBgn0032161	CG4594	NA	NA
FBgn0032162	CG4592	NA	NA
FBgn0032166	CG4619	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032167	CG5853	NA	NA
FBgn0032168	CG13126	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032169	CG4709	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032170	CG4658	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032171	CG5846	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032172	CG5850	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032178	Spn31A	Serpin 31A	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032189	Ripalpha	RPA-interacting protein alpha	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032191	Snx17	Sorting nexin 17	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032192	CG5731	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032193	CG5727	NA	NA
FBgn0032194	CG4901	NA	CG4901 encodes an ATP-dependent RNA helicase involved in neurogenesis and spliceosomal complex disassembly. [Date last reviewed: 2019-03-07]
FBgn0032195	CG4908	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032196	CG5708	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032197	ova	ovaries absent	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032198	eEF1delta	eukaryotic translation elongation factor 1 delta	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032200	CG5676	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032202	REPTOR-BP	REPTOR-binding partner	REPTOR-binding partner (REPTOR-BP) encodes a transcription factor constitutively localized in the nucleus. Together with its binding partner encoded by REPTOR, it mediates much of the transcriptional response observed upon Tor complex 1 inhibition. [Date last reviewed: 2019-03-14]
FBgn0032204	CG4953	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0032205	CG4957	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0032208	Ufd4	Ubiquitin fusion-degradation 4-like	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032210	CYLD	Cylindromatosis	NA
FBgn0032213	CG5390	NA	NA
FBgn0032214	CG4968	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032216	Usp14	Ubiquitin specific protease 14	Ubiquitin specific protease 14 (Usp14) encodes a deubiquitinase that associates with the 19S component of the proteasome in a reversible manner. Its functions include ubiquitin chain disassemblance for mono-ubiquitin recycling, control of protein degradation by the proteasome and regulation of proteasome subtrate interactions. [Date last reviewed: 2019-03-21]
FBgn0032217	CG4972	NA	NA
FBgn0032218	CG5381	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-10-13]
FBgn0032221	Schip1	Schwannomin interacting protein 1	Schwannomin interacting protein 1 (Schip1) encodes a protein that is involved in negative regulation of organ growth by promoting the Hippo signaling pathway. It binds to the products of ex and Tao, activating the phosphorylation of the kinase encoded by hpo. [Date last reviewed: 2018-11-15]
FBgn0032222	Cox10	Cytochrome c oxidase assembly factor 10	NA
FBgn0032223	GATAd	GATAd	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032224	Sps2	Selenophosphate synthetase 2	Selenophosphate synthetase 2 (Sps2) is essential for selenoprotein biosynthesis. It encodes an enzyme that catalyzes the synthesis of selenophosphate from selenide and/or other selenium metabolites. Selenophosphate is an active selenium donor for the formation of selenocysteine. [Date last reviewed: 2018-11-15]
FBgn0032228	CG5367	NA	NA
FBgn0032229	ClpP	Caseinolytic protease proteolytic subunit	NA
FBgn0032231	CG5056	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032234	gny	garnysstan	garnysstan (gny) encodes a glucosyltransferase involved in cuticle barrier formation and thought to have a role in N-glycan biosynthesis and epidermal differentiation. [Date last reviewed: 2019-03-07]
FBgn0032236	mRpS7	mitochondrial ribosomal protein S7	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032242	CG5355	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032243	Klp31E	Kinesin-like protein at 31E	NA
FBgn0032244	RfC3	Replication factor C subunit 3	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032246	Wdfy2	WD repeat and FYVE domain containing 2	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032247	CG5188	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032248	Bug22	Basal body up regulated gene 22	Basal body up regulated gene 22 (Bug22) encodes a ciliary protein involved in cilium organization and assembly. It contributes to multiple processes during spermatogenesis including tubulin polyglycylation, axoneme assembly, sperm individualization and motility. It also contributes to locomotion, dendrite morphogenesis and neuron and muscle development. [Date last reviewed: 2019-03-07]
FBgn0032249	TBC1D16	TBC1 domain family member 16	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032250	holn1	hole-in-one	hole-in-one (holn1) encodes a protein involved in wound healing. [Date last reviewed: 2019-08-01]
FBgn0032251	Nse4	Non-SMC element 4	Non-SMC element 4 (Nse4) encodes a member of the EID (EP300-interacting inhibitor of differentiation) family of proteins. It is the kleisin component of the SMC5/6 protein complex. This complex is critical to genome stability, and is required for homologous DNA recombination-based processes. [Date last reviewed: 2018-11-15]
FBgn0032252	loh	lonely heart	lonely heart (loh) encodes a protein involved in larval heart development and regulation of the extracellular matrix assembly. [Date last reviewed: 2019-08-01]
FBgn0032253	LManI	Lysosomal alpha-mannosidase I	Lysosomal α-mannosidase I (LManI) encodes an enzyme that is involved in mannose metabolism using p-nitrophenyl-alpha-mannoside as a substrate. [Date last reviewed: 2019-09-26]
FBgn0032256	RluA-2	RluA pseudouridine synthase 2	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032258	Cog4	Component of oligomeric golgi complex 4	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032259	CG6144	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032261	CG6094	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032264	Lip4	Lipase 4	NA
FBgn0032290	CG6443	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032292	EMC3	ER membrane protein complex subunit 3	ER Membrane protein Complex 3 (EMC3) encodes a subunit of the ER membrane protein complex (EMC). In fly retinas, EMC has been shown to be essential for the biosynthesis of multi-pass membrane proteins, but not for single-pass membrane proteins and secretory proteins. [Date last reviewed: 2019-03-07]
FBgn0032293	Dpy-30L1	Dpy-30-like 1	Dpy-30-like 1 (Dpy-30L1) encodes a protein that is part of the COMPASS complex, a histone H3K4 methyltransferase complex thought to be responsible for the bulk of the histone H3K4 di- and trimethylation. The product of Dpy-30L1 binds to, and thereby inhibits, the metal-responsive transcription factor encoded by MTF-1. [Date last reviewed: 2019-03-07]
FBgn0032295	CG12299	NA	NA
FBgn0032296	CG6729	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032297	CG17124	NA	NA
FBgn0032298	CG6724	NA	NA
FBgn0032305	CG6700	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032321	YL-1	YL-1	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032322	CG16743	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032329	Art8	Arginine methyltransferase 8	Arginine methyltransferase 8 (Art8) encodes a histone methyltransferase involved in methylation of both histone H3-R2 and arginine. [Date last reviewed: 2019-08-01]
FBgn0032330	Samuel	SAM-motif ubiquitously expressed punctatedly localized protein	SAM-motif ubiquitously expressed punctatedly localized protein (Samuel) encodes a protein that binds to the nuclear receptor encoded by Hr78 and acts as a corepressor. It regulates chromatin silencing and larval growth. [Date last reviewed: 2018-11-15]
FBgn0032339	Wdr59	WD repeat domain 59	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032341	Reps	RALBP1 associated Eps domain containing	NA
FBgn0032343	CG6201	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032346	Csl4	Csl4	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032348	CG4751	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032354	CG4788	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032358	Ppt2	Palmitoyl-protein Thioesterase 2	Palmitoyl-protein Thioesterase 2 (Ppt2) encodes a lysosomal enzyme that removes palmitoyl groups form particular target proteins during protein degradation within the lysosomal compartment. Palmitoylation is critical for the cellular localization and modulation of many signaling proteins. [Date last reviewed: 2019-03-14]
FBgn0032363	Dlg5	Discs large 5	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032364	CG4970	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032373	Vha100-5	Vacuolar H[+] ATPase 100kD subunit 5	NA
FBgn0032378	CycY	Cyclin Y	NA
FBgn0032382	Mal-B2	Maltase B2	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032387	CG16965	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032388	CG6686	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032390	dgt2	dim gamma-tubulin 2	NA
FBgn0032391	escl	escl	escl (escl) encodes an essential component of the Polycomb Repressive Complex 2, whose function is to methylate histone H3K27. Although the product of escl is functionally equivalent to the product of esc, it is not maternally supplied in equally high levels and some homeotic phenotypes occur in the absence of the product of esc. [Date last reviewed: 2019-03-07]
FBgn0032393	Nfs1	Nfs1 cysteine desulfurase	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032394	Hacd1	3-hydroxyacyl-CoA dehydratase 1	NA
FBgn0032395	Wdr81	WD repeat domain 81	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032397	Tom70	Translocase of outer membrane 70	Translocase of outer membrane 70 (Tom70) encodes a mitochondrial protein that may act as a receptor of the TOM complex based on orthology. TOM complex is involved in protein import into mitochondria. The product of Tom70 modulates cell death induced by the expression of the mouse Bax protein. [Date last reviewed: 2019-03-14]
FBgn0032398	CG6766	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032399	CG6785	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032400	CG6770	NA	NA
FBgn0032401	Plzf	Promyelocytic leukemia zinc finger	NA
FBgn0032402	PLCXD	Phosphatidylinositol-specific phospholipase C X domain containing	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032404	RpL7-like	Ribosomal protein L7-like	NA
FBgn0032405	firl	firelighter	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032407	Pex19	Peroxin 19	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032408	CG6712	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032409	Ced-12	Ced-12	Ced-12 (Ced-12) encodes a protein that functions with Dock family members (encoded by mbc or spg) to regulate GTPase activity. It contributes to myoblast fusion, apoptotic cell engulfment, cell migration, and embryonic cellularization. [Date last reviewed: 2018-11-15]
FBgn0032420	CG6583	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032421	crok	crooked	NA
FBgn0032422	atilla	atilla	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032429	CG5446	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032430	Trm1	tRNA methyltransferase 1	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032444	CCT4	Chaperonin containing TCP1 subunit 4	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032445	CG6153	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032446	IFT43	Intraflagellar transport 43	NA
FBgn0032447	PICK1	Protein interacting with C kinase 1	NA
FBgn0032449	CG17036	NA	NA
FBgn0032450	CG5776	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032451	spict	spichthyin	spichthyin (spict) encodes a BMP signaling pathway regulator involved in synaptic growth regulation at neuromuscular junctions. [Date last reviewed: 2019-09-19]
FBgn0032452	CG15484	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-10-13]
FBgn0032453	CG6180	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032454	CG5787	NA	NA
FBgn0032455	Pih1D1	PIH1 domain containing 1	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032456	MRP	Multidrug-Resistance like Protein 1	NA
FBgn0032465	Yip1d1	Yip1 domain-containing 1	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032467	Ube4B	Ubiquitination factor E4B	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032474	DnaJ-H	DnaJ homolog	NA
FBgn0032475	Sfmbt	Scm-related gene containing four mbt domains	Scm-related gene containing four mbt domains (Sfmbt) encodes a subunit of the Polycomb Group protein complex Pho repressive complex (PhoRC). This chromatin binding protein recognizes with high selectivity mono- and dimethylated lysine residues in various histone peptides. [Date last reviewed: 2018-11-15]
FBgn0032476	CG5439	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032477	Alg7	Alg7 dolichyl-phosphate N-acetylglucosaminephosphotransferase	NA
FBgn0032479	CG16974	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032480	Edem2	ER degradation enhancer, mannosidase alpha-like 2	ER degradation enhancer, mannosidase alpha-like 2 (Edem2) encodes a lectin involved in the degradation of proteins during endoplasmic reticulum (ER) stress, which is generated by the presence of unfolded proteins in the ER. [Date last reviewed: 2019-09-12]
FBgn0032481	CG16972	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0032482	Pect	Phosphoethanolamine cytidylyltransferase	NA
FBgn0032485	CG9426	NA	NA
FBgn0032486	mRF1	mitochondrial translation release factor 1	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032487	Ski6	Ski6	Ski6 (Ski6) encodes a protein involved in gene expression regulation. [Date last reviewed: 2019-07-11]
FBgn0032488	CG16812	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032499	Uvrag	UV-resistance associated gene	UV-resistance associated gene (Uvrag) encodes a protein that regulates autophagy and vesicle trafficking with the product of Atg6 and class C vacuolar protein sorting complexes. With the products of Atg6 and Pi3K59F, It forms a PI3K(III) complex and plays roles in receptor downregulation and the establishment of proper cell polarity. It is also critical for proper organ rotation during development by controlling receptor endocytosis and subsequent degradation. [Date last reviewed: 2019-03-21]
FBgn0032509	CG6523	NA	NA
FBgn0032511	ND-B22	NADH dehydrogenase (ubiquinone) B22 subunit	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032512	Bdp1	B double prime 1	B double prime 1 (Bdp1) encodes a transcription factor involved in snRNA gene transcription. [Date last reviewed: 2019-09-12]
FBgn0032513	CG6565	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032514	CG9302	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032515	loqs	loquacious	loquacious (loqs) encodes a double-stranded RNA binding protein with multiple splicing isoforms. loqs-PB and loqs-PA associate with the product of Dcr-1 to facilitate processing of precursor miRNA into mature miRNA, whereas loqs-PD interacts with the product of Dcr-2 to enhance processing of dsRNA into siRNA. [Date last reviewed: 2019-03-14]
FBgn0032516	Ing5	Inhibitor of growth family member 5	Inhibitor of growth family member 5 (Ing5) encodes a histone acetyltransferase that forms part of the Enok complex, which interacts with the product of elg1 to promote the G1/S transition via proliferating cell nuclear antigen (PCNA) unloading. [Date last reviewed: 2019-03-07]
FBgn0032517	CG7099	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032518	RpL24	Ribosomal protein L24	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032520	CG10859	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032521	CG7110	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032524	Hacd2	3-hydroxyacyl-CoA dehydratase 2	NA
FBgn0032586	Tpr2	Tetratricopeptide repeat protein 2	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032587	CG5953	NA	NA
FBgn0032590	CG4631	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-10-13]
FBgn0032596	Prosbeta4	Proteasome beta4 subunit	Proteasome β4 subunit (Prosβ4) encodes a protein involved in proteasomal degradation. [Date last reviewed: 2019-07-11]
FBgn0032597	CG17904	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032598	ChLD3	ChLD3	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032600	BuGZ	Bub3 interacting GLEBS and Zinc finger domain protein	Bub3 interacting GLEBS and Zinc finger domain protein (BuGZ) encodes a protein involved in dendrite morphogenesis. [Date last reviewed: 2019-07-11]
FBgn0032601	yellow-b	yellow-b	yellow-b (yellow-b) is a member of the multifunctional yellow family of genes that encodes a protein involved in color pattering, eggshell integrity and mating behavior. [Date last reviewed: 2018-10-11]
FBgn0032603	CG17928	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032613	Nepl9	Neprilysin-like 9	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032620	CG12288	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032633	Lrch	Leucine-rich-repeats and calponin homology domain protein	Leucine-rich-repeats and calponin homology domain protein (Lrch) encodes a scaffold protein well conserved across animals that associates with actin-rich structures during cell division. Lack of Lrch results in a reduction of fertility and fitness. [Date last reviewed: 2019-03-14]
FBgn0032634	Polr2J	RNA polymerase II subunit J	NA
FBgn0032635	CG15141	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032637	CG5050	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032638	SPH93	Serine protease homolog 93	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032640	Sgt	small glutamine-rich tetratricopeptide containing protein	small glutamine-rich tetratricopeptide containing protein (Sgt) encodes a protein involved in the regulation of the protein folding mediated by chaperones. [Date last reviewed: 2019-09-19]
FBgn0032642	Lamtor3	Late endosomal/lysosomal adaptor, MAPK and MTOR activator 3	Late endosomal/lysosomal adaptor, MAPK and MTOR activator 3 (Lamtor3) encodes a scaffold protein that associates with the MAP kinase kinase and the MAP kinase encoded by Mekk1 and rl respectively. It regulates the vein promoting function of rl during wing imaginal disc development in third instar larvae. [Date last reviewed: 2019-09-26]
FBgn0032643	GCS2beta	Glucosidase 2 beta subunit	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032644	CG5131	NA	NA
FBgn0032646	mEFTs	mitochondrial translation elongation factor Ts	mitochondrial translation elongation factor Ts (mEFTs) encodes a protein predicted to function within mitochondria to recharge the products of mEFTu1 and mEFTu2 with GTP during the elongation phase of mRNA translation. [Date last reviewed: 2019-03-14]
FBgn0032656	CG5674	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032670	CG5783	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032671	JMJD4	Jumonji domain containing 4	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032681	CG10283	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032683	kon	kon-tiki	kon-tiki (kon) (also known as perdido) encodes a single transmembrane protein required to initiate muscle-tendon attachment in a group of embryonic and adult body muscles. kon mutants are embryonic lethal with rounded ventral longitudinal muscles. It concentrates at muscle attachment sites and genetically interacts with integrins. [Date last reviewed: 2019-03-14]
FBgn0032688	CG15160	NA	NA
FBgn0032689	CG10413	NA	NA
FBgn0032690	CG10333	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032691	Atac2	Ada2a-containing complex component 2	Ada2a-containing complex component 2 (Atac2) encodes a protein involved in chromatin organization, intestinal stem cell homeostasis, and histone acetylation. [Date last reviewed: 2019-06-27]
FBgn0032693	Cyp310a1	Cytochrome P450 310a1	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032694	MESR3	Misexpression suppressor of ras 3	NA
FBgn0032698	CG10336	NA	NA
FBgn0032699	CG10383	NA	CG10383 encodes a hydrolase involved in the regulation of glycosylphosphatidylinositol metabolism, determination of lifespan and sleep. [Date last reviewed: 2019-03-07]
FBgn0032700	CG10338	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032701	CG10341	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032702	CG10376	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032703	CG10343	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032704	Jwa	Jwa	NA
FBgn0032705	Grip71	Grip71	NA
FBgn0032715	CG17597	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032717	CG10600	NA	NA
FBgn0032720	mRpL13	mitochondrial ribosomal protein L13	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032721	CG10602	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032723	ssp3	short spindle 3	NA
FBgn0032724	CG10428	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0032725	Nedd8	Nedd8	Nedd8 (Nedd8) encodes a ubiquitin-like polypeptide involved in protein ubiquitination and degradation, via Cullin neddylation. Nedd8-mediated modification has been implicated in signal transduction, cell proliferation and differentiation. [Date last reviewed: 2018-10-11]
FBgn0032726	CG10621	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032727	CG10623	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032728	Tango6	Transport and Golgi organization 6	NA
FBgn0032729	L2HGDH	L-2-hydroxyglutarate dehydrogenase	NA
FBgn0032730	CG10431	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032731	Swip-1	Swiprosin-1	Swiprosin-1 (Swip-1) encodes a calcium binding protein, expressed in fusion competent myoblasts and macrophages of the embryo. [Date last reviewed: 2019-03-14]
FBgn0032732	EMC5	ER membrane protein complex subunit 5	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032744	Ttc19	Tetratricopeptide repeat domain 19	NA
FBgn0032746	CG10470	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032748	CG10492	NA	NA
FBgn0032750	CG10495	NA	NA
FBgn0032751	CG17343	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032752	CG10702	NA	NA
FBgn0032763	CG17568	NA	NA
FBgn0032772	CG17350	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0032773	fon	fondue	fondue (fon) encodes a protein produced by the fat body that is involved in the clotting reaction. [Date last reviewed: 2019-03-07]
FBgn0032774	CG17549	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032775	CG17544	NA	NA
FBgn0032779	Alp12	Alkaline phosphatase 12	NA
FBgn0032780	CG13085	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032781	RtcB	RtcB RNA ligase	NA
FBgn0032782	Rab9	Rab9	Rab9 (Rab9) encodes a member of the Rab subfamily of small GTPases associated with late endosomes. It promotes membrane budding and retrograde recycling of endocytosed materials to the Golgi apparatus. Its roles include recycling of tracheal luminal proteins and tracheal tube length control. [Date last reviewed: 2019-03-14]
FBgn0032783	CG10237	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032785	CG10026	NA	NA
FBgn0032787	CG10195	NA	NA
FBgn0032790	CG10194	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032791	CG18094	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032793	CG10189	NA	NA
FBgn0032796	cyst	cysts	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032797	Hasp	Hig-anchoring scaffold protein	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032798	CG10132	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032799	Dpm1	Dolichyl-phosphate mannosyltransferase subunit 1	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032800	CG10137	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032801	CG10165	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032805	CG10337	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-10-13]
FBgn0032810	CG13077	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032811	Pmvk	Phosphomevalonate kinase	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032812	Hakai	Hakai	Hakai (Hakai) encodes a ring finger type E3 ubiquitin ligase that associates with the cadherin encoded by shg. It is essential for organismal viability and embryonic morphogenesis, but is dispensable for cell viability and proliferation. [Date last reviewed: 2019-03-07]
FBgn0032814	CG10366	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032815	CG10462	NA	NA
FBgn0032816	Nf-YB	Nuclear factor Y-box B	Nuclear factor Y-box B (Nf-YB) encodes a subunit of the nuclear transcription factor Y, which binds to the CCAAT box regulatory sequence. It regulates gene transcription and is involved in eye and thorax development. [Date last reviewed: 2018-10-11]
FBgn0032817	CG10631	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032818	CG10628	NA	NA
FBgn0032819	CG10463	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032820	fbp	fructose-1,6-bisphosphatase	NA
FBgn0032821	CdGAPr	Cd GTPase activating protein-related	Cd GTPase activating protein-related (CdGAPr) encodes a protein that acts in concert with the product of Fak in the formation of the optic stalk, a tubular structure composed of glial cells. [Date last reviewed: 2019-03-07]
FBgn0032822	CG10466	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032833	COX4	Cytochrome c oxidase subunit 4	Cytochrome c oxidase subunit 4 (COX4) encodes a subunit of the cytochrome-c oxidase. It is involved in cell proliferation and golgi structural organisation. [Date last reviewed: 2019-09-12]
FBgn0032845	CG10747	NA	NA
FBgn0032846	Pyroxd1	Pyridine nucleotide-disulfide oxidoreductase domain 1	NA
FBgn0032847	Taf13	TBP-associated factor 13	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032848	nesd	nessun dorma	NA
FBgn0032849	mRpS18B	mitochondrial ribosomal protein S18B	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032858	CG10949	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032859	Arpc2	Actin-related protein 2/3 complex, subunit 2	NA
FBgn0032863	Cdc23	Cell division cycle 23	Cell division cycle 23 (Cdc23) encodes a subunit of the anaphase promoting complex/cyclosome (APC/C). Together with other subunits, it forms a functional subcomplex of the APC/C that binds to the product of shtd and is likely to be involved in activator and substrate binding. [Date last reviewed: 2019-03-07]
FBgn0032864	CG2493	NA	NA
FBgn0032869	CG17470	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032870	CG2608	NA	NA
FBgn0032871	CG2611	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032873	CG2614	NA	NA
FBgn0032876	Cen	Centrocortin	Centrocortin (Cen) encodes a protein that regulates cleavage furrow assembly in the early embryo. It localizes to centrosomes asymmetrically, and to cortical actin structures. [Date last reviewed: 2019-03-07]
FBgn0032877	CG2617	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032880	TM9SF2	Transmembrane 9 superfamily protein member 2	NA
FBgn0032881	Amacr	Alpha-methylacyl-CoA racemase	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032882	Ns4	Nucleostemin 4	NA
FBgn0032883	Rhau	RHAU helicase	RHAU helicase (Rhau) encodes a protein involved in G-quadruplex DNA unwinding. [Date last reviewed: 2019-09-12]
FBgn0032884	Pomp	Pomp	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032886	CG9328	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032889	CG9331	NA	NA
FBgn0032891	Oseg5	Outer segment 5	NA
FBgn0032897	CG9336	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032899	CG9338	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032901	sky	skywalker	skywalker (sky) encodes a RabGAP that genetically interacts with and activates GTPase activity of the product of Rab35 through an unconventional mechanism. It restricts the ability of synaptic vesicles to fuse into a synaptic endosomal compartment, thereby limiting synaptic vesicle associated protein sorting at synaptic endosomes. In line with this function, sky also genetically interacts with components of the ESCRT and HOPS complexes. [Date last reviewed: 2019-03-14]
FBgn0032906	RPA2	Replication protein A2	NA
FBgn0032907	CG9272	NA	NA
FBgn0032908	CG9270	NA	NA
FBgn0032919	CG9253	NA	NA
FBgn0032921	Mpp6	M-phase phosphoprotein 6	NA
FBgn0032922	Coq3	Coenzyme Q3	NA
FBgn0032923	Pld3	Phospholipase D family member 3	NA
FBgn0032924	Nbr	Nibbler	NA
FBgn0032925	CG9246	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032929	Mcm10	Minichromosome maintenance 10	NA
FBgn0032934	CG8679	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032935	Atg18b	Autophagy-related 18b	NA
FBgn0032938	CG8671	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032940	Mondo	Mondo	Mondo (Mondo) encodes a basic helix-loop-helix-leucine zipper transcription factor involved in lipid and carbohydrate metabolism. Together with its binding partner encoded by bigmax, it controls sugar-dependent gene expression, including activation of genes involved in lipogenesis. Mondo mutants are intolerant to dietary sugars and have impaired muscle function. [Date last reviewed: 2018-10-11]
FBgn0032943	Tsp39D	Tetraspanin 39D	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032946	nrv3	nervana 3	nervana 3 (nrv3) encodes one of three beta subunits of the sodium-potassium pump (ATPalpha). nrv3 is expressed in the nervous system, including subsets of the CNS and Johnston's organ neurons, and is required for hearing. [Date last reviewed: 2019-03-14]
FBgn0032949	Lamp1	Lamp1	NA
FBgn0032955	CG2201	NA	NA
FBgn0032956	Cul2	Cullin 2	Cullin 2 (Cul2) encodes a protein that plays important roles during oogenesis. Reduction of the product of Cul2 in somatic cells produces tumorous germaria with excess germline stem cell-like cells due to the elevation of Dpp signaling in the niche. [Date last reviewed: 2019-03-07]
FBgn0032957	CG2225	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0032961	CG1416	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032965	CG11629	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032967	CG1428	NA	NA
FBgn0032968	CG11634	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032974	CG3651	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032979	Clamp	Chromatin-linked adaptor for MSL proteins	Chromatin-linked adaptor for MSL proteins (Clamp) encodes a zinc finger protein that is required to recruit the dosage compensation complex. It is essential in both males and females. It also functions outside of the dosage compensation pathway. [Date last reviewed: 2019-03-07]
FBgn0032981	CG3635	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032986	CG3262	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032987	RpL21	Ribosomal protein L21	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0032988	Tif-IA	Tif-IA	NA
FBgn0032997	CG17486	NA	NA
FBgn0033000	CG14464	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0033005	CG3107	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0033010	Atf6	Atf6	NA
FBgn0033015	d4	d4	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0033017	CG10465	NA	NA
FBgn0033019	CG10395	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0033021	CG10417	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0033028	hrm	hermes	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0033029	Not3	CCR4-NOT transcription complex subunit 3	CCR4-NOT transcription complex subunit 3 (Not3) encodes a poly(A)-specific ribonuclease involved in translation inhibition. [Date last reviewed: 2019-08-01]
FBgn0033032	kune	kune-kune	NA
FBgn0033033	scaf	scarface	NA
FBgn0033038	CG7791	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0033050	Pngl	PNGase-like	NA
FBgn0033051	Strica	Ser/Thr-rich caspase	Ser/Thr-rich caspase (Strica) encodes a member of initiator caspases. It contributes, redundantly or cooperatively with the product of Dronc, to the apoptosis of selective larval neurons during metamorphosis and nurse cells during oogenesis, and competitive apoptosis of heterozygous mutant cells. [Date last reviewed: 2019-03-14]
FBgn0033052	SCAP	SREBP cleavage activating protein	NA
FBgn0033055	Tbce	Tubulin-specific chaperone E	Tubulin-specific chaperone E (Tbce) encodes one of the five tubulin chaperones. It facilitates the folding of α-tubulin, a subunit of α-β tubulin heterodimers. [Date last reviewed: 2019-03-14]
FBgn0033060	CG7849	NA	NA
FBgn0033062	Ars2	Arsenic resistance protein 2	Arsenic resistance protein 2 (Ars2) encodes a protein that binds the cap binding complex and plays roles in small RNA biogenesis. It facilitates miRNA processing from primary miRNAs to pre-miRNAs. In addition, it interacts with the product of Dcr-2, modulates its activity and is required for siRNA-mediated silencing and antiviral defense. [Date last reviewed: 2019-03-21]
FBgn0033079	Fmo-2	Flavin-containing monooxygenase 2	Flavin-containing monooxygenase 2 (Fmo-2) encodes a monooxygenase involved in oxidation-reduction metabolism. [Date last reviewed: 2019-09-12]
FBgn0033081	geminin	geminin	geminin (geminin) encodes a protein that interacts with the replication factor encoded by dup and regulates the Egfr pathway, DNA replication and chromosome ploidy. [Date last reviewed: 2019-03-07]
FBgn0033085	CG15908	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0033086	CG9410	NA	NA
FBgn0033087	Hsepi	Heparan sulfate C5-epimerase	Heparan sulfate C5-epimerase (Hsepi) encodes a heparan sulfate modifying enzyme, which catalyzes the C5-epimerization of glucuronic acid, converting it to iduronic acid. Hsepi loss results in minor morphological defects and lifespan reduction. [Date last reviewed: 2019-03-07]
FBgn0033088	PGAP3	Post-GPI attachment to proteins 3	Post-GPI attachment to proteins 3 (PGAP3) encodes a protein involved in the lipid remodeling steps of glycosylphosphatidylinositol (GPI)-anchor maturation. Lipid remodeling consist in the generation of 2 saturated fatty chains at the sn-2 position of GPI-anchored proteins. The product of PGAP3 is required for the phospholipase A2 activity that removes an acyl-chain at the sn-2 position of GPI-anchors during the remodeling. [Date last reviewed: 2019-03-14]
FBgn0033089	CG17266	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0033092	Rpp25	Ribonuclease P/MRP subunit p25	NA
FBgn0033093	CG3270	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0033095	chk	chaski	NA
FBgn0033100	CG3420	NA	NA
FBgn0033101	CG9436	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0033104	CG15237	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0033113	Spn42Dc	Serpin 42Dc	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0033115	Spn42De	Serpin 42De	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0033117	CG3358	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0033121	Cyp6u1	Cytochrome P450 6u1	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0033122	CG17002	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0033127	Tsp42Ef	Tetraspanin 42Ef	NA
FBgn0033128	Tsp42Eg	Tetraspanin 42Eg	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0033132	Tsp42Ej	Tetraspanin 42Ej	Tetraspanin 42Ej (Tsp42Ej) encodes a lysosomal member protein required for the degradation of endocytosed rhodopsin. It prevents light-induced retinal degeneration. [Date last reviewed: 2019-03-14]
FBgn0033134	Tsp42El	Tetraspanin 42El	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0033153	Gadd45	Growth arrest and DNA damage-inducible 45	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0033155	Br140	Bromodomain-containing protein, 140kD	Bromodomain-containing protein, 140kD (Br140) encodes a histone acetyltransferase that is a component of the Enok complex, which interacts with the product of elg1 via Br140 to promote the G1/S transition via proliferating cell nuclear antigen (PCNA) unloading. [Date last reviewed: 2019-03-07]
FBgn0033159	Dscam1	Down syndrome cell adhesion molecule 1	NA
FBgn0033160	Dhx15	DEAH-box helicase 15	NA
FBgn0033166	Eaf	ELL-associated factor	ELL-associated factor (Eaf) encodes a protein interactor of the ELL homolog encoded by Su(Tpl). It increases the ability of the product of Su(Tpl) to enhance transcription elongation of RNA Polymerase II. [Date last reviewed: 2019-03-07]
FBgn0033169	CG11123	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0033170	sPLA2	secretory Phospholipase A2	NA
FBgn0033174	CG11125	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0033177	CG11141	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0033178	CG11127	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0033179	p47	p47	p47 (p47) encodes a protein involved in nuclear envelope reassembly and rhabdomere development. [Date last reviewed: 2019-09-19]
FBgn0033183	CG1620	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0033184	mEFTu2	mitochondrial translation elongation factor Tu 2	mitochondrial translation elongation factor Tu 2 (mEFTu2) encodes a protein predicted to function within mitochondria to bring aminoacyl-tRNA to the ribosome during the elongation phase of mRNA translation. Unlike the protein encoded by mEFTu1, mEFTu2 product is enriched in the testis, suggesting a testis-specific role for this factor. [Date last reviewed: 2019-03-14]
FBgn0033185	CG1603	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0033186	CG1602	NA	NA
FBgn0033187	PIG-G	Phosphatidylinositol glycan anchor biosynthesis class G	NA
FBgn0033188	Drat	Death resistor Adh domain containing target	Death resistor Adh domain containing target (Drat) encodes a member of the zinc-dependent ADH-like family that is an effector of ethanol-induced apoptosis. [Date last reviewed: 2019-03-07]
FBgn0033190	Gpo2	Glycerophosphate oxidase 2	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0033191	CG1598	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0033192	Corin	Corin	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0033194	Vps13	Vacuolar protein sorting 13	Vacuolar protein sorting 13 (Vps13) encodes a protein located to endosomal membrane that is involved in protein homeostasis. [Date last reviewed: 2018-10-11]
FBgn0033195	CG1360	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0033196	CG1358	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0033199	CG17985	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0033204	CG2065	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0033205	CG2064	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0033206	DCTN4-p62	Dynactin 4, p62 subunit	NA
FBgn0033208	mRpL52	mitochondrial ribosomal protein L52	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0033209	CG12107	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0033210	U2A	U2A	U2A (U2A) encodes a protein component of the U2 snRNP, which combines with other snRNPs on the pre-mRNA to assemble a spliceosome. [Date last reviewed: 2019-03-14]
FBgn0033212	LRR	Leucine-rich repeat	Leucine-rich repeat (LRR) encodes a protein that contributes to the response to insecticides. It regulates the immune response and NIK/NF-kappaB signaling. [Date last reviewed: 2019-09-12]
FBgn0033224	Nop17l	Nop17 like	NA
FBgn0033225	TTLL12	Tubulin tyrosine ligase-like 12	NA
FBgn0033226	puml	pummelig	NA
FBgn0033232	CG12159	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0033233	Kdm4A	Lysine demethylase 4A	Lysine (K)-specific demethylase 4A (Kdm4A) encodes a histone lysine demethylase that catalyzes removal of methyl groups using alpha-ketoglutarate as a cofactor. It demethylates H3K36me3 and is implicated in the demethylation of H3K9me3 and H3K56me3. Its roles include transcription, DNA repair, and heterochromatin silencing. [Date last reviewed: 2019-09-26]
FBgn0033235	CG8728	NA	NA
FBgn0033236	CG14764	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0033240	CG2906	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0033241	CG2915	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0033244	CG8726	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0033246	ACC	Acetyl-CoA carboxylase	Acetyl-CoA carboxylase (ACC) encodes a ubiquitous metabolic enzyme. It catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting substrate for fatty acid synthesis. It is essential in the embryo and in the oenocytes (specialized abdominal cells) for the watertightness of the respiratory system. It is required in the fat body for triglyceride storage and in the muscles for locomotor activity. [Date last reviewed: 2019-03-07]
FBgn0033247	Nup44A	Nucleoporin at 44A	Nucleoporin at 44A (Nup44A) encodes a nuclear pore protein involved in TORC1 signaling, autophagy and oogenesis. [Date last reviewed: 2019-07-11]
FBgn0033258	uno	univalents only	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0033259	Tmem63	Transmembrane protein 63	NA
FBgn0033260	Cul4	Cullin 4	Cullin 4 (Cul4) encodes the molecular scaffold for the CRL4 E3 ubiquitin ligase complex, which catalyzes the ubiquitylation and subsequent destruction of proteins that function in cell growth and proliferation as well as transcription, replication and repair of the genome. [Date last reviewed: 2019-03-07]
FBgn0033261	udd	under-developed	under-developed (udd) encodes a protein that interacts with the products of TAF1B and TAF1C-like, and helps to regulate RNA Polymerase I dependent rRNA transcription. [Date last reviewed: 2019-03-14]
FBgn0033264	Nup50	Nucleoporin 50kD	Nucleoporin 50kD (Nup50) encodes an important protein for TGF-beta signal transduction by mediating the nuclear translocation of the product of Mad. [Date last reviewed: 2019-06-27]
FBgn0033265	coil	coilin	coilin (coil) encodes a protein required for Cajal body formation. [Date last reviewed: 2018-10-11]
FBgn0033266	Socs44A	Suppressor of Cytokine Signaling at 44A	Suppressor of Cytokine Signaling at 44A (Socs44A) encodes a protein that promotes the degradation of interacting proteins by recruiting Cullin/Elongin ubiquitin ligase complexes. It activity negatively regulates JAK/STAT signaling and positively impacts RTK signaling in a context specific manner, which can impact developmental patterning. [Date last reviewed: 2019-03-14]
FBgn0033268	Obp44a	Odorant-binding protein 44a	NA
FBgn0033272	RagC-D	Ras-related GTP binding C/D	NA
FBgn0033273	Gasz	Gasz	Gasz (Gasz) encodes an essential factor for primary piRNA biogenesis. It is predicted to stimulate cleavage of piRNA precursors by the endonuclease encoded by zuc via the recruitment of piRNA precursors and biogenesis factors to the mitochondrial surface. [Date last reviewed: 2019-03-07]
FBgn0033274	CG14757	NA	NA
FBgn0033292	Cyp4ad1	Cytochrome P450 4ad1	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0033302	Cyp6a14	Cytochrome P450 6a14	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0033304	Cyp6a13	Cytochrome P450 6a13	NA
FBgn0033308	CG8736	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0033309	Lnpk	Lunapark	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0033312	CG8642	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0033313	Cirl	Calcium-independent receptor for alpha-latrotoxin	NA
FBgn0033315	beta3GalTII	beta-1,3-Galactosyltransferase II	β-1,3-Galactosyltransferase II (β3GalTII) encodes a protein involved in the synthesis of a common linkage tetrasaccharide structure of heparan (HS) and chondroitin sulfates (CS). Its roles include regulation of several signaling pathways (Hh, Dpp, Wingless) mediated by HS and CS in development. [Date last reviewed: 2019-03-21]
FBgn0033316	Gle1	Gle1 RNA export mediator	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0033317	CG8635	NA	NA
FBgn0033337	CG8272	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0033339	Sec31	Secretory 31	Secretory 31 (Sec31) encodes a protein involved in the innate immune response. [Date last reviewed: 2019-07-11]
FBgn0033340	CG13751	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0033341	MrgBP	MRG/MORF4L binding protein	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0033348	Spt	Spitting Image	Spitting Image (Spt) encodes an F-actin binding and stabilizing protein. Spt and Sry-α represent a novel clade of the Vinculin/α-Catenin superfamily. The product of Spt is maternally provided in early embryos, and it positively regulates F-actin levels during cellularization. [Date last reviewed: 2019-03-14]
FBgn0033349	CG8243	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0033350	CG8237	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0033351	AIMP1	aaRS-interacting multifunctional protein 1	aaRS-interacting multifunctional protein 1 (AIMP1) is predicted to encode one of 3 non-enzymatic factors that combine with eight aminoacyl-tRNA synthetases to form a 'multi-synthetase complex' (MSC). The functional significance of the MSC is unclear, but the non-enzymatic factors are thought to be responsive to diverse signal transduction pathways. [Date last reviewed: 2019-03-07]
FBgn0033352	PAN2	Poly(A)-binding protein-dependent poly(A) ribonuclease 2	NA
FBgn0033354	FANCI	Fanconi anemia complementation group I	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0033356	CG8229	NA	NA
FBgn0033357	Tom7	Translocase of outer membrane 7	Translocase of outer membrane 7 (Tom7) encodes a putative mitochondrial protein that may act as a channel component of the TOM complex based on orthology with the human gene TOMM7. [Date last reviewed: 2019-03-14]
FBgn0033362	CG8172	NA	NA
FBgn0033363	CG13744	NA	CG13744 encodes a CLIP-domain-containing serine protease. [Date last reviewed: 2019-03-07]
FBgn0033364	CG13747	NA	NA
FBgn0033366	Ance-4	Ance-4	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0033367	PPO2	Prophenoloxidase 2	Prophenoloxidase 2 (PPO2) encodes a protein stored in large crystals in the crystal cells (a type of hemocyte cell) that is involved in the melanization reaction. It contributes to melanization around wounds and wasp encapsulation and is thought to be activated by proteolytic cleavage by the product of Hayan. [Date last reviewed: 2019-03-14]
FBgn0033368	CG13743	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0033373	CG8080	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0033375	CG8078	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0033376	CG8777	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0033377	Pgm2a	Phosphoglucomutase 2a	NA
FBgn0033378	tsu	tsunagi	NA
FBgn0033379	Mys45A	Mystery 45A	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0033380	Phax	Phosphorylated adaptor for RNA export	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0033381	GstE13	Glutathione S transferase E13	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0033382	Hydr1	alpha/beta hydrolase 1	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0033387	CG8008	NA	NA
FBgn0033388	CG8046	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0033391	CG8026	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0033392	CG8027	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0033397	Cyp4p3	Cytochrome P450 4p3	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0033400	CG2063	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0033401	Cog6	Component of oligomeric golgi complex 6	NA
FBgn0033402	Myd88	Myd88	Myd88 (Myd88) encodes an adaptor protein involved in in the Toll pathway functioning downstream of the product of Tl and upstream of the product of tub. Toll pathway is a signaling cascade that plays a key role in various developmental and immune processes, notably embryonic dorsoventral patterning and regulation of antimicrobial peptides. [Date last reviewed: 2019-03-14]
FBgn0033413	prel	preli-like	preli-like (prel) encodes a mitochondrial protein in the PRELI/MSF1 family that contributes to the integrity of mitochondrial structures and the activity of respiratory chain complex IV. [Date last reviewed: 2019-03-14]
FBgn0033421	CG1888	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0033422	Or45b	Odorant receptor 45b	Odorant receptor 45b (Or45b) encodes a multi-transmembrane chemoreceptor that mediates response to volatile chemicals. [Date last reviewed: 2019-03-14]
FBgn0033426	Nt5c	5' nucleotidase C	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0033427	Smyd4-1	SET and MYND domain containing, class 4, member 1	NA
FBgn0033428	Urod	Uroporphyrinogen decarboxylase	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0033429	CG12929	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0033431	CG1827	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0033434	CG1902	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0033437	CG12926	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0033438	Mmp2	Matrix metalloproteinase 2	Matrix metalloproteinase 2 (Mmp2) encodes a proteinase that cleaves proteins in the extracellular matrix. It contributes to remodeling the body plan during metamorphosis; matrix and tissue remodeling during axon fasciculation, dendritic reshaping, wound healing, and ovulation; and down-regulating follicle stem cell proliferation. [Date last reviewed: 2019-03-14]
FBgn0033446	CG1648	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0033448	hebe	hebe	NA
FBgn0033449	CG1663	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0033450	Lsm11	Lsm11	Lsm11 (Lsm11) encodes one of the seven proteins that form a heptameric Sm ring in the U7 snRNP, which is a key factor involved in 3' end processing of histone pre-mRNAs. It interacts with the product of FLASH. The two interacting proteins form a biochemical platform that recruits a number of polyadenylation subunits to the U7 snRNP, including the products of Sym, Cpsf100, Cpsf73 and CstF64. [Date last reviewed: 2018-10-11]
FBgn0033451	Marc	Mitochondrial amidoxime reducing component	Mitochondrial amidoxime reducing component (Marc) encodes a protein predicted to be a molybdenum cofactor enzyme. mARC enzymes are believed to be moonlighting enzymes, with two independent reductase functions: the reduction of a broad range of N-hydroxylated compounds, often associated with cellular detoxification, and the reduction of nitrite to nitric oxide. [Date last reviewed: 2021-01-21]
FBgn0033453	Sting	Sting	NA
FBgn0033454	CG1671	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0033457	Ntmt	N-terminal methyltransferase	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0033459	CG12744	NA	NA
FBgn0033460	Sec24AB	Secretory 24AB	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0033463	CG1513	NA	NA
FBgn0033468	CG1418	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0033469	CG12133	NA	NA
FBgn0033471	CG12134	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0033473	CG12128	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0033474	CG1407	NA	NA
FBgn0033475	CG12129	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0033476	oys	oysgedart	oysgedart (oys) encodes a lysophospholipid acyltransferase that is required redundantly with the product of nes for germ cell migration and spermatid individualization. [Date last reviewed: 2019-03-14]
FBgn0033479	PIG-N	Phosphatidylinositol glycan anchor biosynthesis class N	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0033480	mRpL42	mitochondrial ribosomal protein L42	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0033482	CG1371	NA	NA
FBgn0033483	egr	eiger	eiger (egr) encodes the TNF superfamily ligand that activates the intracellular JNK pathway through its receptor encoded by grnd or wgn. Its roles include cell death, tumor suppression, tumor promotion, growth regulation, host defense, pain sensitization, and nutrient response. [Date last reviewed: 2018-10-11]
FBgn0033485	RpLP0-like	Ribosomal protein LP0-like	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0033486	dmpd	dampened	dampened (dmpd) encodes a nuclear F-box protein that acts as a co-activator of the product of bcd in modulating the expression level of its target gene hb. [Date last reviewed: 2019-03-07]
FBgn0033491	CG18011	NA	NA
FBgn0033494	KCNQ	KCNQ potassium channel	KCNQ potassium channel (KCNQ) encodes a voltage-gated channel involved in cardiac muscle contraction. [Date last reviewed: 2019-03-14]
FBgn0033502	CG12910	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0033504	CAP	CAP	CAP (CAP) encodes a protein that localizes to focal adhesions and associates with proteins that regulate cytoskeletal organization, including the product of Vinc. It regulates the assembly and function of two actin-rich structures: the larval muscle attachment site, and the fly chordotonal organs in the larval body wall and in the adult Johnston's organ. [Date last reviewed: 2018-10-11]
FBgn0033507	CG12909	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0033523	CG12895	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0033526	Caf1-105	Chromatin assembly factor 1, p105 subunit	Chromatin assembly factor 1, p105 subunit (Caf1-105) encodes one of the three subunits of Drosophila chromatin assembly factor 1 (CAF-1). It binds to histones and contributes to heterochromatin formation and maintenance, chromatin assembly, and developmental signal transduction such the Notch signaling pathway. [Date last reviewed: 2019-03-07]
FBgn0033527	CG11777	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0033528	trsn	translin	translin (trsn) encodes a protein that, together with the product of Trax, forms the Trsn/Trax complex, a ribonuclease that facilitates RNA-induced silencing complex (RISC) activation and has been implicated in many different processes, including starvation-induced sleep suppression. [Date last reviewed: 2019-03-14]
FBgn0033529	CG17765	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0033538	CG11883	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0033539	Git	G protein-coupled receptor kinase interacting ArfGAP	G protein-coupled receptor kinase interacting ArfGAP (Git) encodes an Arf-GAP that forms a scaffold with the Rho-type guanine nucleotide exchange factor encoded by RtGEF aiding in activation of the kinase encoded by Pak. The product of Git has roles in muscle morphogenesis, synaptic vesicle recycling, and regulation of tissue growth. [Date last reviewed: 2019-10-03]
FBgn0033540	Elp2	Elongator complex protein 2	NA
FBgn0033543	Daao1	D-amino acid oxidase 1	NA
FBgn0033544	CG7220	NA	NA
FBgn0033547	CG12935	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0033548	CG7637	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0033549	mms4	Methyl methanesulfonate sensitivity 4	Methyl methanesulfonate sensitivity 4 (mms4) encodes the non-catalytic subunit of the mus81-mms4 structure-selective endonuclease that functions in DNA repair. [Date last reviewed: 2019-03-14]
FBgn0033550	CG12341	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0033551	CG7222	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0033555	RpS15Ab	Ribosomal protein S15Ab	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0033556	CG12343	NA	NA
FBgn0033557	CG12325	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0033566	CG18004	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0033569	CG12942	NA	NA
FBgn0033570	ND-B14	NADH dehydrogenase (ubiquinone) B14 subunit	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0033571	Polr2E	RNA polymerase II, I and III subunit E	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0033581	CG12391	NA	NA
FBgn0033584	CG7737	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0033605	CG9067	NA	NA
FBgn0033607	CG9062	NA	NA
FBgn0033608	CG13220	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0033609	Fbl6	F-box and leucine-rich repeat protein 6	NA
FBgn0033615	CG7741	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0033616	CG7745	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0033624	CG12384	NA	NA
FBgn0033627	CG13204	NA	CG13204 encodes a protein predicted to be a transcriptional regulator. CG13204 overexpression can partially rescue hng1 loss of function, suggesting either epistasis or an overlaping function between hng1 and CG13204. [Date last reviewed: 2019-03-07]
FBgn0033635	Prip	Prip	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0033636	tou	toutatis	toutatis (tou) encodes a transcription factor that activates proneural expression via positive regulation of the product of pnr. It is involved in chromatin remodeling and nervous system development. [Date last reviewed: 2019-08-01]
FBgn0033638	CG9005	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0033639	CG9003	NA	NA
FBgn0033645	CG13196	NA	NA
FBgn0033649	pyr	pyramus	pyramus (pyr) encodes a Fibroblast growth factor (FGF) and ligand for the FGF receptor encoded by htl. It regulates the development of somatic and visceral muscle in the mesoderm, cardioblasts and glial cells. Its roles include acting as a chemoattractant in directional cell migration, and regulating adhesion, differentiation, and cell survival. [Date last reviewed: 2019-03-14]
FBgn0033653	CG13192	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0033656	S2P	site-2 protease	NA
FBgn0033661	CG13185	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0033663	ERp60	Endoplasmic reticulum p60	NA
FBgn0033665	Zip48C	Zinc/iron regulated transporter-related protein 48C	NA
FBgn0033669	PI31	Proteasome inhibitor 31 kDa	NA
FBgn0033672	rho-7	rhomboid-7	rhomboid-7 (rho-7) encodes an intramembrane serine protease of the rhomboid family present in the inner membrane of mitochondria. It regulates mitochondrial fusion during spermatogenesis and muscle development. rho-7 genetically interacts with fog, Opa1 and Pink1. [Date last reviewed: 2019-03-14]
FBgn0033673	CG8298	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0033677	CG8321	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0033683	CG18343	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0033686	Hen1	Hen1 methyltransferase	Hen1 methyltransferase (Hen1) encodes a methyltransferase that methylates the terminal 2' hydroxyl group of small interfering RNAs and Piwi-interacting RNAs. It probably protects the 3' ends of small RNAs from degradation. [Date last reviewed: 2019-03-07]
FBgn0033688	Prp8	pre-mRNA processing factor 8	pre-mRNA processing factor 8 (Prp8) is an essential gene that encodes the largest and most highly conserved splicing factor. It is a core component of the U5 snRNP, with a key function in pre-mRNA processing catalyzed by the spliceosome. [Date last reviewed: 2019-03-14]
FBgn0033690	EndoG	Endonuclease G	Endonuclease G (EndoG) encodes an enzyme with endodeoxyribonuclease and endoribonuclease activity. It is involved in germ cell programmed cell death, mitochondrion inheritance and spermatid development. [Date last reviewed: 2019-09-19]
FBgn0033691	CG8860	NA	NA
FBgn0033692	wash	washout	washout (wash) encodes a Wiskott-Aldrich syndrome protein that polymerizes branched actin through activation of the Arp2/3 complex, as well as bundles and/or crosslinks actin and microtubules. It functions as a downstream effector of the product of Rho1 in a context dependent manner. It is involved in nuclear and cytoplasmic cytoskeleton related cellular processes, including ooplasmic streaming, endosome recycing, hemocyte migration, and global nuclear organization. [Date last reviewed: 2019-03-21]
FBgn0033698	CG8858	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0033699	RpS11	Ribosomal protein S11	NA
FBgn0033712	mIF3	mitochondrial translation initiation factor 3	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0033713	CG8841	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0033715	CG8490	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0033716	Den1	Deneddylase 1	NA
FBgn0033717	CG8839	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0033724	CG8501	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0033734	CG8520	NA	NA
FBgn0033735	Dera	Deoxyribose-phosphate aldolase	NA
FBgn0033737	Nup54	Nucleoporin 54kD	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0033738	DUBAI	Deubiquitinating apoptotic inhibitor	NA
FBgn0033739	Dyb	Dystrobrevin	NA
FBgn0033740	dgt5	dim gamma-tubulin 5	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0033741	CG8545	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0033744	Dh44-R2	Diuretic hormone 44 receptor 2	Diuretic hormone 44 receptor 2 (Dh44-R2) encodes a protein that exhibits diuretic hormone receptor activity. It is involved in G protein-coupled receptor signaling pathways, hormone-mediated signaling pathways, and response to salt stress. [Date last reviewed: 2019-07-11]
FBgn0033749	achi	achintya	achintya (achi) encodes a homeodomain transcription factor (TGIF subclass) that is required along with homeodomain protein encoded by vis for meiotic division in spermatogenesis. [Date last reviewed: 2019-03-07]
FBgn0033750	CG13151	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0033751	CG8818	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-10-13]
FBgn0033752	CG8569	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0033755	ClC-b	Chloride channel-b	Chloride channel-b (ClC-b) encodes a chloride transmembrane transporter involved in phagocytosis. [Date last reviewed: 2019-09-12]
FBgn0033756	CG17760	NA	NA
FBgn0033757	muskelin	muskelin	NA
FBgn0033761	CG8778	NA	NA
FBgn0033762	ZnT49B	Zinc transporter 49B	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0033763	CG8646	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0033766	Nup188	Nucleoporin 188kDa	NA
FBgn0033769	CG8768	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0033775	Cyp9h1	Cytochrome P450 9h1	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0033777	CG17574	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0033781	CG13319	NA	NA
FBgn0033782	sug	sugarbabe	sugarbabe (sug) encodes a transcription factor that regulates the expression of insulin-like peptides and genes involved in lipid and carbohydrate metabolism. It is a direct target of the sugar sensor encoded by Mondo and its expression is also promoted by the product of daw. [Date last reviewed: 2018-10-11]
FBgn0033783	CG17019	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0033784	SCCRO3	Squamous cell carcinoma-related oncogene 3	Squamous cell carcinoma-related oncogene 3 (SCCRO3) encodes a protein involved in the regulation of protein neddylation. [Date last reviewed: 2019-09-19]
FBgn0033785	Sans	Scaffold protein containing ankyrin repeats and SAM domain	Scaffold protein containing ankyrin repeats and SAM domain (Sans) encodes a putative scaffolding protein containing three ankyrin repeats and a sterile alpha motif domain. [Date last reviewed: 2019-03-14]
FBgn0033787	CG13321	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0033799	GLaz	Glial Lazarillo	Glial Lazarillo (GLaz) encodes a lipid binding protein of the Lipocalin family, which are small extracellular proteins with a single-domain beta-barrel structure. It is expressed in subsets of central and peripheral glial cells and in hemocytes. It regulates longevity, stress resistance, and behavior. [Date last reviewed: 2018-10-11]
FBgn0033806	FLASH	FLICE-associated huge protein	FLICE-associated huge protein (FLASH) encodes a metazoan-specific protein that plays an essential role in 3' end processing of replication-dependent histone pre-mRNAs. It localizes to histone locus bodies, which are microscopically detectable nuclear foci that form in the vicinity of histone gene clusters. [Date last reviewed: 2019-03-07]
FBgn0033808	CG4627	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0033809	CG4630	NA	NA
FBgn0033810	CG4646	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0033812	Pex13	Peroxin 13	Peroxin 13 (Pex13) encodes a peroxisome protein important for sperm development. [Date last reviewed: 2019-03-14]
FBgn0033813	fsd	fates-shifted	fates-shifted (fsd) encodes an F-box protein with a role in the gradient formation of the product of bcd and fatemap specification through targeting bcd protein for ubiquitination and degradation. [Date last reviewed: 2019-03-07]
FBgn0033814	Qsox1	Quiescin sulfhydryl oxidase 1	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0033816	CG4679	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0033836	CG18278	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0033842	cbc	crowded by cid	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0033844	bbc	bb in a boxcar	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0033845	mars	mars	mars (mars) encodes a microtubule-associated protein that shuttles between the mitotic spindle and the nucleus. It is required for mitotic spindle attachment to the centrosome. [Date last reviewed: 2018-10-11]
FBgn0033846	mip120	Myb-interacting protein 120	Myb-interacting protein 120 (mip120) encodes the sequence-specific DNA-binding protein of the MuvB core complex. The MuvB core binds to the oncoprotein encoded by Myb and the Rbf-E2f2-Dp tumor suppressor complex, thereby controlling the expression of many genes, including critical regulators of the cell cycle. [Date last reviewed: 2019-03-21]
FBgn0033853	CG6145	NA	NA
FBgn0033859	fand	fandango	fandango (fand) encodes a subunit of the NTC/Prp19 complex, which is essential for efficient spliceosome activation. It regulates the efficiency of splicing of zygotic transcripts and their abundance. It is required for normal cellularization, tracheal cell migration, and epidermal morphogenesis in the embryo. [Date last reviewed: 2018-10-18]
FBgn0033871	CG13339	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-10-13]
FBgn0033875	CG6357	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0033876	Syngr	Synaptogyrin	Synaptogyrin (Syngr) encodes a synaptic vesicle protein implicated in vesicle endocytosis during the bulk endocytosis process. It is the sole Drosopohila homolog of the synaptophysin/synaptogryin synaptic vesicle family of proteins. [Date last reviewed: 2019-03-14]
FBgn0033879	Echs1	Enoyl-CoA hydratase, short chain 1	NA
FBgn0033880	CG6553	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0033883	CG16935	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0033884	CG13344	NA	NA
FBgn0033886	Rpn13	Regulatory particle non-ATPase 13	NA
FBgn0033889	CG6701	NA	NA
FBgn0033890	Ctf4	Chromosome transmission fidelity 4	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0033891	CG8067	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0033897	Rcd1	Reduction in Cnn dots 1	Reduction in Cnn dots 1 (Rcd1) encodes a protein involved in centriole replication and transcription regulation. [Date last reviewed: 2019-09-19]
FBgn0033899	CG13016	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0033900	CysRS-m	Cysteinyl-tRNA synthetase, mitochondrial	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0033901	O-fut1	O-fucosyltransferase 1	NA
FBgn0033902	eIF3m	eukaryotic translation initiation factor 3 subunit m	eukaryotic translation initiation factor 3 subunit m (eIF3m) encodes a non core component of the EIF3 translation initiation factor. The product of eIF3m functions during caspase mediated remodeling of the syncytial testis, where it interacts with the apoptosome. [Date last reviewed: 2019-03-07]
FBgn0033903	CG8323	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0033905	CG18324	NA	NA
FBgn0033906	ReepB	Receptor expression enhancing protein B	NA
FBgn0033907	mRpS16	mitochondrial ribosomal protein S16	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0033912	RpS23	Ribosomal protein S23	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0033913	CG8468	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0033915	CG8485	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0033916	Usp20-33	Ubiquitin specific protease 20/33	Ubiquitin specific protease 20/33 (Usp20-33) encodes a deubiquitinase involved in nervous system development. [Date last reviewed: 2018-10-18]
FBgn0033918	CG8531	NA	NA
FBgn0033919	CG8547	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0033924	CG8613	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0033925	CG8617	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0033926	Arc1	Activity-regulated cytoskeleton associated protein 1	NA
FBgn0033928	Arc2	Arc2	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0033929	Tfb1	Transcription factor B1	Transcription factor B1 (Tfb1) encodes a subunit of the Transcription factor II H complex (TFIIH). TFIIH operates in RNA polymerase I and II-mediated transcription, DNA repair and cell cycle regulation. [Date last reviewed: 2019-03-14]
FBgn0033934	CG17385	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0033935	Sin1	SAPK-interacting protein 1	NA
FBgn0033945	CG12868	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0033948	CG12863	NA	NA
FBgn0033951	CG10139	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0033961	ND-B15	NADH dehydrogenase (ubiquinone) B15 subunit	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0033971	CG10209	NA	CG10209 encodes a DNA binding nuclear apoptosis-inducing factor involved in the apoptotic process. [Date last reviewed: 2019-03-07]
FBgn0033972	Ciao1	Ciao1	NA
FBgn0033973	HPS1	Hermansky-Pudlak Syndrome 1	NA
FBgn0033978	Cyp6a23	Cytochrome P450 6a23	NA
FBgn0033980	Cyp6a20	Cytochrome P450 6a20	Cyp6a20 (Cyp6a20) encodes a protein that may function to degrade aggression-promoting pheromones based on indirect observations such as its expression pattern and the increased aggressive behavior shown in Cyp6a20 mutants. [Date last reviewed: 2019-03-07]
FBgn0033984	Lap1	Lap1	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0033987	ckn	caskin	caskin (ckn) encodes a cytoplasmic adaptor protein that intreacts with the products of Lar and dock. It is required for axon growth and guidance. [Date last reviewed: 2019-03-07]
FBgn0033988	pcs	parcas	NA
FBgn0033989	CG7639	NA	NA
FBgn0033990	CG10265	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0033993	CG8089	NA	NA
FBgn0033994	CG7544	NA	NA
FBgn0033995	GPHR	Golgi pH Regulator	Golgi pH Regulator (GPHR) encodes an anion channel that regulates Golgi luminal pH. It is expressed in both ER and Golgi apparatus and is necessary for proper function of the secretory pathway. [Date last reviewed: 2019-03-07]
FBgn0033996	CG11807	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0033998	row	relative of woc	relative of woc (row) encodes a zinc-finger protein involved in transcription regulation that is required for the factor encoded by HP1c to bind chromatin. [Date last reviewed: 2019-03-14]
FBgn0034000	CG11808	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0034001	mRpL41	mitochondrial ribosomal protein L41	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0034002	CG8079	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0034005	ItgaPS4	Integrin alphaPS4 subunit	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0034008	CG8152	NA	NA
FBgn0034009	CG8155	NA	CG8155 encodes a Rab GTPase activator of the Rab signaling pathway. It's involved in border follicle cell migration, regulation of GTPase activity, intracellular trafficking of vesicles and determination of lifespan. [Date last reviewed: 2019-03-07]
FBgn0034010	CG8157	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0034011	CG8160	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0034013	unc-5	unc-5	unc-5 (unc-5) encodes a netrin receptor involved in motor axon guidance and glial migration as well as netrin-mediated repulsion during salivary gland migration. [Date last reviewed: 2019-03-21]
FBgn0034025	Pgant1	Polypeptide N-Acetylgalactosaminyltransferase 1	NA
FBgn0034027	CG8187	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0034029	eIF2Bgamma	eukaryotic translation initiation factor 2B subunit gamma	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0034032	CG8195	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0034033	CG8204	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0034035	CG8207	NA	NA
FBgn0034046	tun	tungus	NA
FBgn0034049	bdg	bedraggled	bedraggled (bdg) encodes a putative transporter involved in the fate commitment of the R3/R4 pair of photoreceptor cells. [Date last reviewed: 2019-09-12]
FBgn0034050	bug	bunker gear	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0034051	Mlf	Myelodysplasia/myeloid leukemia factor	NA
FBgn0034054	CG8366	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0034057	CG8314	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0034058	Pex11ab	Peroxin 11a/b	NA
FBgn0034060	Tmem131	Transmembrane protein 131	NA
FBgn0034061	Ufc1	Ubiquitin-fold modifier conjugating enzyme 1	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0034062	CG8388	NA	NA
FBgn0034063	CG8389	NA	NA
FBgn0034065	Rrp42	Rrp42	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0034066	EMC7	ER membrane protein complex subunit 7	NA
FBgn0034067	CG8399	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0034068	casp	caspar	caspar (casp) encodes a protein that inhibits the immune deficiency pathway, but not the Toll pathway, by blocking cleavage and nuclear translocation of the product of Rel. [Date last reviewed: 2019-03-07]
FBgn0034071	CG8405	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0034072	Dg	Dystroglycan	Dystroglycan (Dg) encodes a major non-integrin extracellular matrix (ECM) receptor that connects the ECM to the actin cytoskeleton. It regulates animal survival and temperature preference, muscle integrity, myotendinous and neuromuscular junction formation and function, nervous system development, axon pathfinding, rhabdomere differentiation, neuronal stem cell division and epithelial polarity. [Date last reviewed: 2019-03-07]
FBgn0034073	CG8414	NA	NA
FBgn0034075	Asph	Aspartyl beta-hydroxylase	Aspartyl β-hydroxylase (Asph) may be involved in peptidyl-amino acid modification based on orthology. It might be involved in neurogenesis since lack of Asph function enhances the expanded htt-fragment-induced eye phenotype. [Date last reviewed: 2019-03-07]
FBgn0034083	lbk	lambik	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0034084	CG8435	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0034086	CG8441	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0034087	clu	clueless	clueless (clu) encodes a cytoplasmic ribonucleoprotein that is required for mitochondrial function. It functions in part with protein complexes at the outer mitochondrial membrane, such as the ribosome, the translocase complex TOM and the mitophagy proteins encoded by park and Pink1. Loss of clu causes mitochondrial oxidative damage, decreased ATP and lethality. [Date last reviewed: 2019-03-07]
FBgn0034091	mrj	mrj	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0034093	CG15706	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0034094	Tsf3	Transferrin 3	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0034098	krimp	krimper	NA
FBgn0034109	CG7747	NA	NA
FBgn0034110	Atg9	Autophagy-related 9	Autophagy-related 9 (Atg9) encodes an integral membrane protein acting as a membrane carrier for forming autophagosomes. It regulates TOR and JNK signaling pathways via autophagy. [Date last reviewed: 2019-07-11]
FBgn0034113	CG8060	NA	NA
FBgn0034114	CG4282	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0034117	CG7997	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0034118	Nup62	Nucleoporin 62kD	NA
FBgn0034126	jtb	jetboil	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0034138	RpS15	Ribosomal protein S15	Ribosomal protein S15 (RpS15) encodes a protein that plays a role in assembly, structure and function of the ribosome and functions in protein synthesis. It is phosphorylated by the kinase encoded by Lrrk, causing protein synthesis upregulation. [Date last reviewed: 2018-10-18]
FBgn0034141	CG8311	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0034142	CG8306	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0034158	CG5522	NA	NA
FBgn0034166	CG6472	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0034172	CG6665	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0034175	ste24b	ste24b prenyl protease type I	ste24b prenyl protease type I (ste24b) encodes a protein that, along with the products of ste24a and ste24c, are paralogous (tandemly duplicated) type I prenyl proteases. The product of ste24b plays an essential role in the male germline. [Date last reviewed: 2019-03-14]
FBgn0034176	ste24a	prenyl protease type I	prenyl protease type I (ste24a) encodes a protein that, along with the products of ste24b and ste24c, are paralogous (tandemly duplicated) type I prenyl proteases. [Date last reviewed: 2019-03-14]
FBgn0034177	AsnRS-m	Asparaginyl-tRNA synthetase, mitochondrial	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0034179	CG6805	NA	NA
FBgn0034180	Ehbp1	Eps15 homology domain containing protein-binding protein 1	Eps15 homology domain containing protein-binding protein 1 (Ehbp1) encodes a protein that mediates asymmetric protein secretion. It regulates the trafficking and secretion of distinct Notch signaling components and extracellular membrane proteins. [Date last reviewed: 2019-09-12]
FBgn0034181	CG8963	NA	NA
FBgn0034182	SmydA-7	SET and MYND domain containing, arthropod-specific, member 7	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0034184	CG9646	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0034186	CG8950	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0034187	CG6967	NA	NA
FBgn0034191	CG6984	NA	NA
FBgn0034194	CG15611	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0034198	CG11400	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0034199	Gbp1	Growth-blocking peptide 1	Growth-blocking peptide 1 (Gbp1) encodes a cytokine that regulates the humoral immune response. [Date last reviewed: 2019-09-12]
FBgn0034200	Gbp2	Growth-blocking peptide 2	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0034210	Camp	Cathelicidin-like antimicrobial protein	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0034214	CG6550	NA	NA
FBgn0034215	Mtap	Methylthioadenosine phosphorylase	Methylthioadenosine phosphorylase (Mtap) encodes an enzyme that plays a key role in the methionine salvage pathway and in the production of endogenous cellular adenine. [Date last reviewed: 2018-10-18]
FBgn0034217	Lhr	Lethal hybrid rescue	Lethal hybrid rescue (Lhr) encodes a protein required to repress transposable element and satellite DNA expression. It also has a gain-of-function phenotype of causing lethality in F1 male hybrids between D. melanogaster and D. simulans. [Date last reviewed: 2019-03-14]
FBgn0034219	mthl4	methuselah-like 4	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0034221	CG10764	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0034223	Tes	Testin	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0034225	veil	veil	veil (veil) encodes a GPI-linked protein that functions as a 5'-nucleotidase. [Date last reviewed: 2019-09-19]
FBgn0034230	CG4853	NA	NA
FBgn0034231	APC10	Anaphase Promoting Complex subunit 10	NA
FBgn0034232	CG4866	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0034237	eIF3b	eukaryotic translation initiation factor 3 subunit b	NA
FBgn0034240	MESR4	Misexpression suppressor of ras 4	Misexpression suppressor of ras 4 (MESR4) encodes a plant homeodomain finger protein required for proper activation of the EGFR signaling pathway. It contributes to innate immunity, cellular response to hypoxia, regulation of fat storage, and embryonic development. [Date last reviewed: 2019-03-14]
FBgn0034242	CG14480	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0034243	Ns2	Nucleostemin 2	NA
FBgn0034245	UQCR-6.4	Ubiquinol-cytochrome c reductase 6.4 kDa subunit	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0034246	Dcr-2	Dicer-2	Dicer-2 (Dcr-2) encodes a member of the RNase III family of double-stranded RNA-specific endonucleases. It acts in the RNAi pathway by cutting long dsRNA into siRNAs. It helps defend flies against viral infection, particularly RNA viruses. It also processes long, partially double-stranded endogenous transcripts (hairpin RNAs) into endo-siRNAs. [Date last reviewed: 2019-03-07]
FBgn0034248	CG14483	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0034249	RhoGAP54D	Rho GTPase activating protein at 54D	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0034253	CG10936	NA	NA
FBgn0034255	Oxp	Oxpecker	Oxpecker (Oxp) is an evolutionarily young, tandem duplicate gene of the piRNA pathway member encoded by rhi. It supports female fertility and transposon silencing in the female germline. [Date last reviewed: 2018-10-18]
FBgn0034258	eIF3c	eukaryotic translation initiation factor 3 subunit c	NA
FBgn0034259	P32	P32	P32 (P32) encodes an evolutionarily conserved mitochondrial protein that functions in presynaptic calcium signaling and neurotransmitter release as well as chromatin metabolism. [Date last reviewed: 2019-03-14]
FBgn0034261	HPS4	Hermansky-Pudlak Syndrome 4	Hermansky-Pudlak Syndrome 4 (HPS4) encodes a tethering factor that regulates gene silencing by small RNAs via endosomal trafficking. [Date last reviewed: 2019-03-07]
FBgn0034265	Snx16	Sorting nexin 16	Sorting nexin 16 (Snx16) encodes a protein that regulates synaptic growth at the neuromuscular junction. [Date last reviewed: 2019-09-19]
FBgn0034269	Hyccin	Hyccin	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0034270	PIG-A	Phosphatidylinositol glycan anchor biosynthesis class A	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0034271	Vps50	Vacuolar protein sorting 50	NA
FBgn0034277	OstDelta	Oligosaccharide transferase Delta subunit	Oligosaccharide transferase Δ subunit (OstΔ) encodes a protein involved in the cellular encapsulation response. [Date last reviewed: 2019-09-26]
FBgn0034282	Mapmodulin	Mapmodulin	NA
FBgn0034299	CG5757	NA	NA
FBgn0034300	CG5098	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0034304	CG5742	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0034307	CG10914	NA	NA
FBgn0034308	Naus	Nausicaa	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0034310	Nup75	Nucleoporin 75kD	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0034312	CG10916	NA	CG10916 encodes a zinc ion binding protein with ubiquitin-protein transferase activity. It is involved in intracellular signal transduction, determination of lifespan, protein ubiquitination and hypoxia. [Date last reviewed: 2019-03-07]
FBgn0034313	CG5726	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0034314	nopo	no poles	no poles (nopo) encodes a RING domain-containing E3 ubiquitin ligase that is essential for early embryogenesis. It positively regulates caspase-dependent cell death. [Date last reviewed: 2019-03-14]
FBgn0034315	CG5721	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0034345	CG5174	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0034346	PIG-O	Phosphatidylinositol glycan anchor biosynthesis class O	NA
FBgn0034351	rswl	roswell	NA
FBgn0034354	GstE11	Glutathione S transferase E11	NA
FBgn0034360	CG10927	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0034361	mRpS28	mitochondrial ribosomal protein S28	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0034362	CG5323	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0034365	CG5335	NA	NA
FBgn0034366	Atg7	Autophagy-related 7	Autophagy-related 7 (Atg7) encodes an E1-type ligase for the autophagic ubiquitin-like proteins encoded by Atg8a and Atg12. Its roles include autophagosome formation, maintaining neuromuscular function and normal lifespan. [Date last reviewed: 2019-03-07]
FBgn0034368	zda	zonda	zonda (zda) encodes an immunophillin of the FKBP family that localizes at the endosomal reticulum. It physically interacts with the products of Atg1 and Pi3K59F and is required for omegasome biogenesis and for starvation-induced autophagy. [Date last reviewed: 2018-10-18]
FBgn0034371	Ntan1	N-terminal amidohydrolase 1	NA
FBgn0034379	CG15073	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0034380	Vps51	Vacuolar protein sorting 51	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0034389	Mctp	Multiple C2 domain and transmembrane region protein	Multiple C2 domain and transmembrane region protein (Mctp) encodes a regulator of both neuronal synaptic plasticity and neurotransmitter secretion. [Date last reviewed: 2019-09-12]
FBgn0034391	CG15080	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0034392	MFS15	Major Facilitator Superfamily Transporter 15	NA
FBgn0034396	CG15097	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0034397	CG15082	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-10-13]
FBgn0034398	CG15098	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0034399	CG15083	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0034400	CG15099	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0034401	MetRS	Methionyl-tRNA synthetase	Methionyl-tRNA synthetase (MetRS) encodes an enzyme that catalyzes the covalent attachment of methionine to methionyl-tRNA, an essential first step of protein translation. [Date last reviewed: 2019-03-14]
FBgn0034402	CG15084	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0034403	CG18190	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0034405	Jheh2	Juvenile hormone epoxide hydrolase 2	Juvenile hormone epoxide hydrolase 2 (Jheh2) encodes an enzyme that hydrolyzes cis-stilbene oxide. Jheh2 expression changes are associated with increased tolerance to oxidative stress. [Date last reviewed: 2019-03-07]
FBgn0034408	sano	serrano	serrano (sano) encodes an apically-enriched cytosolic protein that contributes to trachea development and to the planar cell polarity pathway through binding to the product of dsh. [Date last reviewed: 2019-03-14]
FBgn0034411	CG18605	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0034417	CG15117	NA	NA
FBgn0034418	CG15118	NA	NA
FBgn0034419	CG15111	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0034420	CG10737	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0034422	CG7137	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0034425	CG11906	NA	NA
FBgn0034430	mip40	Myb-interacting protein 40	Myb-interacting protein 40 (mip40) encodes a subunit of the MuvB core complex. The MuvB core binds to the oncoprotein encoded by Myb and the Rbf-E2f2-Dp tumor suppressor complex, thereby controlling the expression of many genes, including critical regulators of the cell cycle. [Date last reviewed: 2019-03-21]
FBgn0034432	CG7461	NA	NA
FBgn0034433	EndoB	Endophilin B	Endophilin B (EndoB) encodes a protein belonging to the endophilin protein family that functions in the process of membrane binding and deformation. It contributes to oogenesis and fecundity. [Date last reviewed: 2019-03-07]
FBgn0034436	CG11961	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0034438	CG9416	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0034442	CG11257	NA	NA
FBgn0034443	cer	crammer	NA
FBgn0034447	CG7744	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0034451	TBCB	tubulin-binding cofactor B	tubulin-binding cofactor B (TBCB) encodes one of the cofactors required for the assembly of functional α/β-Tubulin dimers needed for microtubule assembly. It is essential for microtubule-associated transport and cell polarity, but not for cell division. [Date last reviewed: 2019-03-14]
FBgn0034452	Oseg6	Outer segment 6	NA
FBgn0034455	CG11007	NA	NA
FBgn0034476	Toll-7	Toll-7	Toll-7 (Toll-7) encodes a plasma membrane Toll receptor that binds to viral glycoproteins, leading to the activation of antiviral defenses including autophagy. [Date last reviewed: 2018-10-18]
FBgn0034488	Hacl	2-hydroxyacyl-CoA lyase	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0034491	Hsl	Hormone-sensitive lipase	Hormone-sensitive lipase (Hsl) encodes a protein involved in lipid storage. [Date last reviewed: 2019-03-07]
FBgn0034493	CG8908	NA	NA
FBgn0034494	CG10444	NA	NA
FBgn0034495	CG11788	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0034498	CG16868	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0034500	CG11200	Carbonyl reductase	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0034501	CG13868	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0034503	MED8	Mediator complex subunit 8	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0034504	CG8929	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0034521	Mgat1	Mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase	Mannosyl (α-1,3-)-glycoprotein β-1,2-N-acetylglucosaminyltransferase (Mgat1) encodes an enzyme involved in the synthesis of paucimannose N-glycans. It is required in the CNS, with involvement in locomotion, brain development and lifespan. [Date last reviewed: 2019-09-26]
FBgn0034523	Nnf1a	Nnf1a	Nnf1a (Nnf1a) encodes a component of the Mis12 complex, which is an essential constituent of the kinetochore. [Date last reviewed: 2019-03-14]
FBgn0034527	CG9945	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0034528	CG11180	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0034529	FAM21	Family with sequence similarity 21	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0034530	Rcd6	Reduction in Cnn dots 6	NA
FBgn0034534	maf-S	maf-S	NA
FBgn0034535	CG11110	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0034537	DMAP1	DNA methyltransferase 1 associated protein 1	DNA methyltransferase 1 associated protein 1 (DMAP1) encodes an evolutionarily conserved nuclear innate immune factor. It interacts with the NF-κB transcription factor encoded by Rel and modulates the activation of the immune deficiency pathway in complex with chromatin remodeling factors. Its roles also include larval-pupal development and cell survival. [Date last reviewed: 2019-03-07]
FBgn0034542	Fem-1	Fem-1	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0034543	galla-1	galla-1	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0034564	CG9344	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0034569	dgt3	dim gamma-tubulin 3	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0034570	CG10543	NA	NA
FBgn0034572	CG9346	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0034573	Sou	Souji	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0034576	ND-B14.7	NADH dehydrogenase (ubiquinone) B14.7 subunit	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0034577	cpa	capping protein alpha	capping protein alpha (cpa) encodes an actin-binding protein that, along with the product of cpb, binds to the fast growing ends of actin filaments to restrict the addition or loss of actin monomers. It limits the nuclear translocation of the Hippo pathway mediator encoded by yki and restricts JNK signaling. It maintains epithelial integrity and controls the balance between proliferation and apoptosis in the wing imaginal disc. It plays important roles during oogenesis, as well as maintaining neuronal homeostasis. [Date last reviewed: 2018-10-18]
FBgn0034578	CG15653	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-10-13]
FBgn0034579	mRpL54	mitochondrial ribosomal protein L54	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0034583	CG10527	NA	NA
FBgn0034585	Rbpn-5	Rabaptin-5	Rabaptin-5 (Rbpn-5) encodes a Rab GTPase binding protein involved in regulation of endosome size. [Date last reviewed: 2019-06-27]
FBgn0034590	Magi	Magi	Magi (Magi) encodes a molecular scaffolding protein that is involved in adherens junction (AJ) organization. Magi is ubiquitously expressed and its product localizes at AJ with the Par polarity complex. [Date last reviewed: 2018-10-18]
FBgn0034598	CG4266	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0034599	hng1	hinge1	NA
FBgn0034611	MFS16	Major Facilitator Superfamily Transporter 16	NA
FBgn0034614	CG9752	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0034617	Panx	Panoramix	Panoramix (Panx) encodes a nuclear protein with an essential role in piRNA-guided transcriptional silencing, interacting directly or indirectly with the product of piwi. It is required for fertility. [Date last reviewed: 2019-03-14]
FBgn0034618	CG9485	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0034626	CG10795	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0034627	eEFSec	eukaryotic translation elongation factor, selenocysteine-specific	eukaryotic translation elongation factor, selenocysteine-specific (eEFSec) encodes a protein involved in the incorporation of selenocysteine during protein translation. [Date last reviewed: 2019-03-07]
FBgn0034628	Acox57D-p	acyl-Coenzyme A oxidase at 57D proximal	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0034629	Acox57D-d	acyl-Coenzyme A oxidase at 57D distal	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0034631	TAF1C-like	TATA box-binding protein-associated factor RNA polymerase I subunit C-like	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0034634	CG10494	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-10-13]
FBgn0034638	CG10433	NA	NA
FBgn0034641	mahj	mahjong	mahjong (mahj) encodes a protein involved in regulation of cell cycle, proliferation and cellular fitness. Epithelial cells lacking mahj function are out competed by their wild type neighbors. [Date last reviewed: 2019-03-14]
FBgn0034643	CG10321	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0034644	CG10082	NA	NA
FBgn0034645	ND-B12	NADH dehydrogenase (ubiquinone) B12 subunit	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0034646	Rae1	Rae1	Rae1 (Rae1) encodes a nucleoporin member of the WD40-repeat β propeller protein super family. Biological roles of the pleiotropic Rae1 gene product include poly(A)+ mRNA export, cell cycle regulation, male meiosis control and male germ cell post-meiotic differentiation. [Date last reviewed: 2019-03-14]
FBgn0034650	NC2alpha	Negative Cofactor 2alpha	Negative Cofactor 2α (NC2α) encodes a protein that, together with the product of NC2β forms the negative cofactor 2 complex (NC2), which represses transcription from TATA box-dependent core promoters and activates transcription from DPE-dependent core promoters. [Date last reviewed: 2019-03-14]
FBgn0034654	eIF3k	eukaryotic translation initiation factor 3 subunit k	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0034657	LBR	Lamin B receptor	NA
FBgn0034674	CG9304	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0034684	CG13501	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0034688	CG11474	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0034689	CG2921	NA	NA
FBgn0034691	Synj	Synaptojanin	Synaptojanin (Synj) encodes a synaptic Phosphoinositide phosphate (PtdInsP) phosphatase that catalyzes the hydrolysis of phosphate groups from phosphorylated inositols. It is recruited or stabilized by the product of EndoA to endocytic membranes, and it catalyzes dephosphorylation reactions implicated in the uncoating of nascent endocytic vesicles. When the product of Synj dephosphorylates phosphoinositides on nascent vesicles, endocytic adaptors with affinity for these lipids will leave the membrane to uncoat the vesicle. [Date last reviewed: 2019-03-14]
FBgn0034694	Plekhm1	Pleckstrin homology and RUN domain containing M1	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0034697	GM130	Golgi matrix protein 130 kD	Golgi matrix protein 130 kD (GM130) encodes a protein involved in Golgi compartmental organization and regulation of dendrite morphogenesis. [Date last reviewed: 2019-07-11]
FBgn0034703	CG3045	NA	NA
FBgn0034704	Fbxo42	F-box protein 42	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0034705	CG11170	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0034707	MED16	Mediator complex subunit 16	NA
FBgn0034708	Vps35	Vacuolar protein sorting 35	Vacuolar protein sorting 35 (Vps35) encodes a component of the retromer complex that acts to recycle membrane proteins to the Golgi or plasma membrane from endocytosed vesicles. [Date last reviewed: 2018-10-18]
FBgn0034709	Swim	Secreted Wg-interacting molecule	Secreted Wg-interacting molecule (Swim) encodes a secreted protein that binds to the product of wg and may function in its spreading. [Date last reviewed: 2019-03-14]
FBgn0034718	wdp	windpipe	windpipe (wdp) encodes a regulator of the JAK/STAT pathway. It is involved in intestinal homeostasis, trachea development and synaptic target recognition. [Date last reviewed: 2019-09-26]
FBgn0034722	Rtf1	Rtf1	Rtf1 (Rtf1) encodes a transcription elongation factor that acts downstream of the products of Ubc6 and Bre1 in regulating the histone modification activity of the Set1/COMPASS complex. It regulates Notch signaling. [Date last reviewed: 2019-03-14]
FBgn0034726	PolE4	DNA polymerase epsilon subunit 4	DNA polymerase epsilon subunit 4 (PolE4) encodes an accessory, non-catalytic subunit of the major replicative polymerase epsilon. It is one of the maternal target genes of the transcription factor encoded by dl and is regulated by the DRE/DREF pathway. [Date last reviewed: 2020-07-30]
FBgn0034727	mRpS29	mitochondrial ribosomal protein S29	NA
FBgn0034728	rad50	rad50	rad50 (rad50) encodes a protein belonging to the SMC family and RAD50 subfamily that is involved in DNA repair. It is required for double-strand break repair and telomere maintenance. [Date last reviewed: 2019-03-14]
FBgn0034729	CG10344	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0034733	CG4752	NA	NA
FBgn0034734	CG4554	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0034735	CG4610	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0034736	gas	gasoline	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0034741	CG4269	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0034742	CG4294	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0034743	RpS16	Ribosomal protein S16	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0034744	Vps20	Vacuolar protein sorting 20	Vacuolar protein sorting 20 (Vps20) encodes a member of the ESCRT-III complex, which sorts certain endocytosed receptors for degradation via the multivesicular body. As part of this complex, the product of Vps20 is also involved in abscission following cytokinesis. [Date last reviewed: 2019-03-21]
FBgn0034745	CG4329	NA	NA
FBgn0034748	CG17807	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0034750	CG3732	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0034753	CG2852	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0034756	Cyp6d2	Cytochrome P450 6d2	Cyp6d2 (Cyp6d2) encodes a member of the cytochrome P450 oxidase protein family and is involved in the detoxification of toxic compounds. Two common Cyp6d2 alleles found in many Dmel stocks result in extreme sensitivity to camptothecin. [Date last reviewed: 2019-03-07]
FBgn0034758	CG13510	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0034761	CG4250	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0034763	RYBP	Ring and YY1 Binding Protein	Ring and YY1 Binding Protein (RYBP) encodes a ubiquitin interacting protein. It interacts with epigenetic regulators of the Polycomb and trithorax groups to control post-translational histone modifications. The product of RYBP is involved in regulation of the innate immune response and cell death/cell survival, and the control of morphogenesis. [Date last reviewed: 2019-03-14]
FBgn0034786	CG13531	NA	NA
FBgn0034791	EMC8-9	ER membrane protein complex subunit 8/9	ER Membrane protein Complex 8-9 (EMC8-9) encodes a subunit of the ER membrane protein complex (EMC). In fly retinas, EMC has been shown to be essential for the biosynthesis of multi-pass membrane proteins, but not for single-pass membrane proteins and secretory proteins. [Date last reviewed: 2019-03-07]
FBgn0034792	YME1L	YME1 like ATPase	YME1 like ATPase (YME1L) encodes an AAA protease localized at the mitochondrial inner membrane. It is involved in mitochondrial quality control and its loss causes male sterility, premature aging, and neuromuscular degenerative phenotypes. [Date last reviewed: 2018-10-18]
FBgn0034793	asrij	asrij	asrij (asrij) encodes a conserved ovarian carcinoma immunoreactive antigen domain-containing endosomal protein that maintains stemness. It positively regulates JAK/STAT signalling and negatively regulates the Notch pathway. It interacts with the GTP-bound form of the product of Arf79F to regulate hematopoiesis and immunity. [Date last reviewed: 2018-10-18]
FBgn0034797	nahoda	nahoda	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0034800	CG3788	NA	NA
FBgn0034802	CNBP	CCHC-type zinc finger nucleic acid binding protein	NA
FBgn0034803	CG9849	NA	NA
FBgn0034804	CG3831	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0034814	CG9890	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0034816	CG3085	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0034817	Art7	Arginine methyltransferase 7	NA
FBgn0034849	CG3500	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0034853	Ice1	Interacts with the C terminus of ELL 1	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0034854	Golgin245	Golgin-245	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0034856	yellow-d2	yellow-d2	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0034858	eIF2Bdelta	eukaryotic translation initiation factor 2B subunit delta	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0034859	CG3520	NA	NA
FBgn0034876	wmd	wing morphogenesis defect	wing morphogenesis defect (wmd) encodes an essential WD-repeat protein that is required for wing development and motor behavior. [Date last reviewed: 2019-03-21]
FBgn0034877	levy	levy	NA
FBgn0034878	pita	pita	pita (pita) encodes an architectural chromatin protein essential for embryonic development that organizes open chromatin in the regulatory regions (predominantly promoters). pita product functions include enhancer blocking, support of distant interactions, protection from spreading of repressed chromatin and recruitment of transcription factors. [Date last reviewed: 2018-09-13]
FBgn0034879	Rrp4	Rrp4	Rrp4 (Rrp4) encodes a protein involved in gene expression regulation. [Date last reviewed: 2019-07-11]
FBgn0034885	Eglp4	Entomoglyceroporin 4	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0034887	St1	Sulfotransferase 1	Sulfotransferase 1 (St1) encodes one out of 4 sulfotransferases that catalyze the sulfonation of many proteins, lipids and glycosaminoglycans. [Date last reviewed: 2019-03-14]
FBgn0034893	mRpL43	mitochondrial ribosomal protein L43	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0034894	sigmar	salivary glands marred	salivary glands marred (sigmar) encodes a TNFAIP8-like (TIPE) protein family member. Its expression levels are responsive to the TNF ligand encoded by egr. The product of sigmar contribute to JNK signaling modulation, cytoskeletal remodeling and autophagy. [Date last reviewed: 2019-03-14]
FBgn0034897	Sesn	Sestrin	Sestrin (Sesn) encodes a stress-inducible protein that suppresses accumulation of reactive oxygen species and inhibits the TORC1 signaling pathway, which allows it to regulate oxidative damage. [Date last reviewed: 2019-03-14]
FBgn0034902	CG5532	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0034908	CG5543	NA	NA
FBgn0034909	pippin	pippin	NA
FBgn0034913	Snap29	Synaptosomal-associated protein 29kDa	Synaptosomal-associated protein 29kDa (Snap29) encodes a member of the SNARE (soluble N-ethylmaleimide-sensitive factor-attachment protein (SNAP) receptor) family. It is involved in regulation of autophagy, endocytic recycling and cell division. [Date last reviewed: 2018-10-18]
FBgn0034914	CG5554	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0034915	eIF6	eukaryotic translation initiation factor 6	NA
FBgn0034918	Pym	Partner of Y14 and Mago	NA
FBgn0034919	CG5569	NA	NA
FBgn0034921	DCP1	Decapping protein 1	Decapping protein 1 (DCP1) encodes a subunit of the mRNA decapping holoenzyme. It is involved in osk mRNA localization and miRNA-mediated gene silencing. [Date last reviewed: 2019-09-19]
FBgn0034923	Upf3	Upf3	Upf3 (Upf3) encodes a protein that regulates targets of the nonsense-mediated mRNA decay pathway. This pathway participates in homeostatic gene expression regulation and plays a quality control role in the elimination of mRNAs with premature termination codons. The product of Upf3 is involved in cell cycle progression and general developmental rate. [Date last reviewed: 2019-03-21]
FBgn0034925	CG5339	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0034933	CG3735	NA	NA
FBgn0034936	Stoml2	Stomatin like 2	NA
FBgn0034938	CG3803	NA	NA
FBgn0034939	thoc5	thoc5	NA
FBgn0034940	CG16787	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-10-13]
FBgn0034945	CG10904	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0034946	CG3065	NA	NA
FBgn0034948	PPP1R15	Protein phosphatase 1 regulatory subunit 15	Protein phosphatase 1 regulatory subunit 15 (PPP1R15) encodes a regulatory subunit of protein phosphatase 1. It mediates the dephosphorylation of the translation initiation factor encoded by eIF2α. This antagonises the effects of the stress sensing kinases encoded by PEK and Gcn2 promoting cap-dependent translation. [Date last reviewed: 2019-03-14]
FBgn0034950	Pask	PAS kinase	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0034951	CG3860	NA	NA
FBgn0034956	CG4324	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0034958	CG3907	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0034959	Xxylt	Xyloside xylosyltransferase	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0034961	CG3163	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0034962	MAN1	MAN1	MAN1 (MAN1) encodes a protein that functions as a tissue-specific antagonist of BMP signaling. [Date last reviewed: 2019-09-26]
FBgn0034963	Not11	CCR4-NOT transcription complex subunit 11	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0034964	IntS1	Integrator 1	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0034965	ppk29	pickpocket 29	pickpocket 29 (ppk29) encodes a putative non-voltage gated cation channel that belongs to the Degenerin/Epithelial sodium channel (DEG/ENaC) family. It contributes to pheromone signaling and neuronal excitability. [Date last reviewed: 2019-03-14]
FBgn0034966	CG13563	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0034968	RpL12	Ribosomal protein L12	Ribosomal protein L12 (RpL12) encodes a protein of the large subunit of the ribosome. It regulates transcription of ribosomal proteins and ribosome biogenesis genes as well as interacting with the Enhancer of Trithorax and Polycomb protein encoded by corto. [Date last reviewed: 2018-10-18]
FBgn0034970	yki	yorkie	yorkie (yki) encodes a transcriptional co-activator protein that is negatively regulated by Hippo signaling, which promotes its cytoplasmic localization. It functions together with DNA binding proteins, such as the product of sd, to activate transcription of a wide range of downstream targets, including genes that promote growth. [Date last reviewed: 2019-03-21]
FBgn0034971	Gpat4	Glycerol-3-phosphate acyltransferase 4	Glycerol-3-phosphate acyltransferase 4 (Gpat4) encodes a de novo synthase of lysophosphatidic acid. [Date last reviewed: 2019-09-26]
FBgn0034975	enok	enoki mushroom	enoki mushroom (enok) encodes a MYST family histone acetyltransferase that acetylates lysine residues on histones, including H3K23, to regulate gene transcription. It contributes to stem cell self-renewal, oogenesis and neural development. [Date last reviewed: 2019-03-07]
FBgn0034976	CG4049	NA	NA
FBgn0034982	Naa35	N(alpha)-acetyltransferase 35	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0034985	CG3328	NA	NA
FBgn0034986	mRpS17	mitochondrial ribosomal protein S17	NA
FBgn0034988	cN-IIIB	cytosolic 5'-nucleotidase IIIB	NA
FBgn0034989	CG3356	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0034997	CG3376	NA	NA
FBgn0035001	Slik	Sterile20-like kinase	Sterile20-like kinase (Slik) encodes a member of the Sterile-20 kinase family. It acts via Raf to promote cell proliferation in imaginal disc epithelia. Independently, Slik acts via the product of Moe to support epithelial integrity. [Date last reviewed: 2019-03-14]
FBgn0035016	CG4612	NA	NA
FBgn0035020	CG13585	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0035021	CG4622	NA	NA
FBgn0035023	ITP	Ion transport peptide	Ion transport peptide (ITP) encodes three identified alternative splice-forms of neuropeptides, one short and two longer forms. The short isoform is produced in several neurosecretory neurons and interneurons in the CNS controling the evening peak of locomotor activity of the fly. [Date last reviewed: 2019-03-07]
FBgn0035024	CG11414	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0035025	uri	unconventional prefoldin RPB5 interactor	NA
FBgn0035026	Fcp1	TFIIF-interacting CTD phosphatase	NA
FBgn0035027	CG3511	NA	NA
FBgn0035028	Start1	Start1	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0035032	ATPsynF	ATP synthase, subunit F	NA
FBgn0035033	CG3548	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0035035	Samtor	S-adenosylmethionine sensor upstream of TORC1	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0035036	CG4707	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0035039	Adck1	aarF domain containing kinase 1	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0035044	CG3663	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0035046	ND-19	NADH dehydrogenase (ubiquinone) 19 kDa subunit	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0035047	Pof	Painting of fourth	Painting of fourth (Pof) encodes a protein that binds to nascent RNA from actively transcribed genes and increases their expression levels. It specifically targets the 4th chromosome and two loci on the X-chromosome. [Date last reviewed: 2019-03-14]
FBgn0035049	Mmp1	Matrix metalloproteinase 1	Matrix metalloproteinase 1 (Mmp1) encodes a proteinase that cleaves proteins in the extracellular matrix. It is involved in tissue histolysis and remodeling during metamorphosis, tracheal remodeling, wound healing, wing regeneration, neoplastic growth, and circadian behavior. It has been used as a reporter for JNK signaling since it is upregulated by the pathway. [Date last reviewed: 2019-03-14]
FBgn0035059	CG3894	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0035060	Eps-15	Epidermal growth factor receptor pathway substrate clone 15	Epidermal growth factor receptor pathway substrate clone 15 (Eps-15) encodes a multi-domain adaptor protein involved in endocytosis. It interacts with several other endocytic factors such as those encoded by shi, stnB, Dap160 and AP-2α. It is enriched at sites of endocytosis and is required for normal synaptic bouton development and vesicle endocytosis during high frequency stimulation. [Date last reviewed: 2018-10-18]
FBgn0035063	CG3594	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0035064	TyrRS-m	Tyrosyl-tRNA synthetase, mitochondrial	Tyrosyl-tRNA synthetase, mitochondrial (TyrRS-m) encodes an enzyme that catalyzes the ligation of tyrosine to the mitochondrial-encoded tRNA-Tyr. The TyrRS-m protein is encoded by a nuclear gene and imported to the mitochondria where it functions in mitochondrial protein synthesis. [Date last reviewed: 2018-10-18]
FBgn0035065	CG3589	NA	NA
FBgn0035073	CG16896	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0035082	CG2811	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0035083	Tina-1	Troponin C-akin-1	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0035084	CG15861	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0035085	CG3770	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0035087	CG2765	NA	NA
FBgn0035088	CG3776	NA	NA
FBgn0035091	CG3829	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0035099	CG6845	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0035101	p130CAS	p130CAS	p130CAS (p130CAS) encodes an SH3 domain-containing protein phosphorylated by Src kinases. It contributes to integrin-mediated adhesion and in vertebrate cells is phosphorylated in response to mechanical stretch. [Date last reviewed: 2019-03-14]
FBgn0035102	CG7049	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0035106	rno	rhinoceros	rhinoceros (rno) encodes a nuclear protein that functions in the Egfr signaling pathway, downstream of MAP kinase activation, and regulates transcription of Egfr targets. It is involved in cell differentiation and developmental patterning. [Date last reviewed: 2019-03-14]
FBgn0035107	mri	mrityu	mrityu (mri) encodes a BTB/POZ domain containing protein. Its expression is regulated by the product of klu during retinal apoptosis. mri protein is phosphorylated upon egg activation, and is required for early embryo development and for the normal sensory perception of touch. [Date last reviewed: 2018-10-18]
FBgn0035109	CG13876	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0035110	thoc7	thoc7	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0035111	Dis3l2	Dis3 like 3'-5' exoribonuclease 2	Dis3 like 3'-5' exoribonuclease 2 (Dis3l2) encodes a 3'-5'-exoribonuclease involved in catabolism of miRNA and tRNA. [Date last reviewed: 2019-09-12]
FBgn0035113	pyx	pyrexia	NA
FBgn0035120	wac	wee Augmin	wee Augmin (wac) encodes a subunit of the hetero-octomeric Augmin complex, which functions to recruit the gamma-tubulin ring complex to pre-existing microtubules, facilitating microtubule-dependent microtubule nucleation. [Date last reviewed: 2018-10-18]
FBgn0035121	Tudor-SN	Tudor staphylococcal nuclease	NA
FBgn0035122	mRpL17	mitochondrial ribosomal protein L17	NA
FBgn0035132	mthl10	methuselah-like 10	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0035137	CG1233	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0035140	BORCS6	BLOC-1 related complex subunit 6	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0035141	Cypl	Cyclophilin-like	NA
FBgn0035142	Hipk	Homeodomain interacting protein kinase	Homeodomain interacting protein kinase (Hipk) encodes a protein that belongs to the DYRK family kinases. It can modulate signaling pathways including Wingless, Notch, Hippo, Hedgehog, JNK, and cell death. It plays roles in development, proliferation and patterning of many tissues, including the eye, wing, and the embryo. [Date last reviewed: 2019-03-07]
FBgn0035144	Kah	Kahuli	Kahuli (Kah) encodes a member of the Snail/Scratch family of transcription factors, which regulate transcription by binding the E-box motif ACAGGTG. [Date last reviewed: 2019-03-14]
FBgn0035145	MED14	Mediator complex subunit 14	NA
FBgn0035146	CG13893	NA	NA
FBgn0035147	Gale	UDP-galactose 4'-epimerase	UDP-galactose 4'-epimerase (Gale) encodes an enzyme that contributes to galactose catabolism and larval lymph gland hemopoiesis. It epimerizes UDP-glucose to UDP-galactose and UDP-N-acetylglucosamine to UDP-N-acetylgalactosamine. [Date last reviewed: 2019-03-07]
FBgn0035148	CG3402	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0035149	MED30	Mediator complex subunit 30	NA
FBgn0035150	Rev1	DNA polymerase Rev1	Rev1 DNA directed polymerase (Rev1) encodes a translesion DNA polymerase with deoxycytidyl transferase activity. It interacts with multiple other translesion polymerases and plays roles in tolerance and repair of DNA damage. [Date last reviewed: 2019-09-26]
FBgn0035151	CG17129	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0035152	CG3386	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0035153	ebd1	earthbound 1	earthbound 1 (ebd1) encodes a transcription cofactor that functions in the Wingless/Wnt signal transduction pathway. It promotes the interaction between the products of arm and pan and helps recruit the product of arm to chromatin. The product of ebd1 functions in a context-specific manner and is important for the development of indirect flight muscles. [Date last reviewed: 2019-03-07]
FBgn0035154	hiro	highroad	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0035155	RabX6	RabX6	NA
FBgn0035158	CG13895	NA	NA
FBgn0035159	CG13896	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-10-13]
FBgn0035160	hng3	hinge3	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0035161	CG13898	NA	NA
FBgn0035162	Sf3b3	Splicing factor 3b subunit 3	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0035164	CG13901	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0035165	CG13887	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0035166	JMJD5	Jumonji domain containing 5	NA
FBgn0035167	Gr61a	Gustatory receptor 61a	NA
FBgn0035169	Dci	Dodecenoyl-CoA delta-isomerase	Dodecenoyl-CoA delta-isomerase (Dci) encodes a protein that, when overexpressed, extends lifespan, enhances stress tolerance to oxidative and starvation stress and activates the product of foxo. [Date last reviewed: 2019-03-07]
FBgn0035173	CG13907	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0035181	CG9205	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0035189	CG9119	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0035194	Psf1	Partner of Sld Five 1	Psf1 (Psf1) encodes a subunit of the Cdc45/Mcm2-7/GINS (CMG) complex, which is associated with an ATP-dependent DNA helicase function and is involved in the regulation of the mitotic G1/S transition. [Date last reviewed: 2019-09-19]
FBgn0035203	Acat2	Acetyl-CoA acetyltransferase 2	NA
FBgn0035204	Nt5a	5' nucleotidase A	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0035205	Ctr9	Ctr9	Ctr9 (Ctr9) encodes a highly conserved member of the polymerase-associated factor 1 complex, which controls a number of transcriptional and epigenetic processes. It is involved in the proliferation and terminal differentiation of the central nervous system. [Date last reviewed: 2019-03-21]
FBgn0035206	sturkopf	sturkopf	sturkopf (sturkopf) encodes an evolutionary conserved lipid droplet-associated protein. In the absence of lipid droplets, the protein localizes to the endoplasmic reticulum. [Date last reviewed: 2019-09-26]
FBgn0035207	Herc4	HECT and RLD domain containing E3 ubiquitin ligase 4	HECT and RLD domain containing E3 ubiquitin ligase 4 (Herc4) encodes a HECT-type E3 ubiquity ligase that is involved in the host defense against Gram-positive bacteria mediated by Toll pathway. [Date last reviewed: 2018-10-18]
FBgn0035209	msd1	mitotic spindle density 1	mitotic spindle density 1 (msd1) encodes a subunit of the hetero-octameric Augmin complex. The complex binds and localises to microtubules, where it recruits gamma tubulin, facilitating new microtubule nucleation. It has a crucial role in ensuring enough microtubules are generated within the mitotic spindle to facilitate chromosome segregation. [Date last reviewed: 2019-03-14]
FBgn0035210	msd5	mitotic spindle density 5	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0035211	CG2211	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0035213	CG2199	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0035227	Iml1	Increased minichromosome loss 1	Increased minichromosome loss 1 (Iml1) encodes a component of the highly conserved GAP Activity Towards Rags 1 (GATOR1) complex, which inhibits the activity of the product of Tor in response to amino acid starvation. The product of Iml1, as well as the other GATOR1 components encoded by Nprl2 and Nprl3, regulates early meiotic progression. [Date last reviewed: 2019-03-07]
FBgn0035228	CG12091	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0035229	pns	pinstripe	NA
FBgn0035231	Pcyt2	Phosphocholine cytidylyltransferase 2	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0035232	CG12099	NA	NA
FBgn0035233	Pex10	Peroxin 10	Peroxin 10 (Pex10) encodes a peroxisome protein important for sperm development. [Date last reviewed: 2019-03-14]
FBgn0035235	CG7879	NA	NA
FBgn0035236	CG12004	NA	NA
FBgn0035237	CG13917	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0035238	CG12104	NA	CG12104 encodes a HMG-box containing protein expressed in the spermatogonia and spermatocytes. [Date last reviewed: 2019-03-07]
FBgn0035241	CG12105	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0035243	CG13926	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0035244	ABCB7	ATP binding cassette subfamily B member 7	ATP binding cassette subfamily B member 7 (ABCB7) encodes a transporter that likely dimerizes to form a functional transporter. It may act in the mitochondria to transport substrates necessary for the maturation of ICS proteins, which are involved in iron homeostasis. [Date last reviewed: 2019-03-07]
FBgn0035246	CG13928	NA	NA
FBgn0035247	Mettl2	Methyltransferase like 2	NA
FBgn0035248	CG13919	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-10-13]
FBgn0035249	CG17249	NA	NA
FBgn0035251	Vta1	Vesicle trafficking 1	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0035252	CG7970	NA	NA
FBgn0035253	Srrm234	Serine-arginine repetitive matrix 2/3/4	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0035254	CG7974	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0035262	CG18171	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0035263	CG12035	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0035266	Gk2	Glycerol kinase 2	NA
FBgn0035268	CG8001	NA	NA
FBgn0035270	CG13933	NA	NA
FBgn0035271	CG2021	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0035272	mRpL46	mitochondrial ribosomal protein L46	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0035283	CG12024	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0035285	CG12025	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0035286	CG13924	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0035287	CG13937	NA	NA
FBgn0035294	Mfap1	Microfibril-associated protein 1	NA
FBgn0035295	Cnb	Centrobin	Centrobin (Cnb) encodes a protein that localizes to the daughter centriole. In neuroblasts, its centriolar localization results in peri-centriolar material retention during interphase. This function requires the phosphorilation of the product of Cnb by the kinase encoded by polo. In the neurons of type I sensory organs, the product of Cnb is necessary and sufficient to inhibit basal body function. [Date last reviewed: 2019-03-07]
FBgn0035298	SCOT	Succinyl-CoA:3-ketoacid CoA transferase	NA
FBgn0035309	CG15879	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0035312	CG15820	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0035318	CG9018	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0035321	CG1275	NA	NA
FBgn0035323	CG13807	NA	NA
FBgn0035333	CG1317	NA	NA
FBgn0035334	CG8993	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0035335	mRpL23	mitochondrial ribosomal protein L23	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0035336	CG9004	NA	NA
FBgn0035337	CG15877	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0035344	Cyp4d20	Cytochrome P450 4d20	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0035346	CG1146	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0035348	CG16758	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0035355	CG16985	NA	NA
FBgn0035356	CG16986	NA	NA
FBgn0035357	MEP-1	MEP-1	MEP-1 (MEP-1) encodes a zinc finger protein that associates with the ATP-dependent nucleosome remodeler encoded by Mi-2. It cooperates with the product of Mi-2 in the repression of cell type-specific genes. [Date last reviewed: 2019-03-14]
FBgn0035358	CG14949	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0035359	CG1143	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-10-13]
FBgn0035370	Non2	Novel nucleolar protein 2	NA
FBgn0035371	AhcyL1	Adenosylhomocysteinase like 1	Adenosylhomocysteinase like 1 (AhcyL1) encodes a protein that, together with the product of AhcyL2, belongs to AHCY-like proteins. AhcyL1 and AhcyL2 products have lost their canonical enzymatic functions due to critical mutations in their AHCY-domains. However, via hetero-multimerization, the products of AhcyL1 and AhcyL2 can suppress the activity of the enzyme encoded by Ahcy, which catalyzes the hydrolysis of S-Adenosylhomocysteine. The presence of a N-terminal IRBIT domain confers AhcyL1 and AhcyL2 proteins new functions in Ca[2+] signaling, intracellular pH regulation and production of deoxyribonucleotides. [Date last reviewed: 2019-03-21]
FBgn0035372	CG12093	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0035374	mRpS35	mitochondrial ribosomal protein S35	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0035375	Pgant6	Polypeptide N-Acetylgalactosaminyltransferase 6	NA
FBgn0035383	CPT2	Carnitine palmitoyltransferase 2	Carnitine palmitoyltransferase 2 (CPT2) encodes an enzyme required for the beta-oxidation of long-chain fatty acids. [Date last reviewed: 2019-09-12]
FBgn0035388	CG2162	NA	NA
FBgn0035390	scramb2	scramblase 2	scramblase 2 (scramb2) encodes a protein that, together with the product of scramb1, has a modulatory function in the process of neurotransmission. They have a significant role in scrambling of phospholipids across the plasma membrane during apoptosis. [Date last reviewed: 2019-03-14]
FBgn0035392	CG1271	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0035393	CG16753	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0035397	PAN3	Poly(A) specific ribonuclease subunit PAN3	NA
FBgn0035400	CG11537	NA	NA
FBgn0035401	Alg2	ALG2, alpha-1,3/1,6-mannosyltransferase	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0035402	Usp5	Ubiquitin specific protease 5	Ubiquitin specific protease 5 (Usp5) encodes an essential enzyme that cleaves unanchored lysine48-linked polyubiquitin chains. It is involved in photoreceptor differentiation, neuron pathfinding and apoptosis. [Date last reviewed: 2019-03-21]
FBgn0035405	CG15812	NA	NA
FBgn0035407	Asciz	ASCIZ zinc finger protein	ASCIZ zinc finger protein (Asciz) encodes a transcription factor that regulates the expression of ctp, which encodes a LC8 dynein light chain. The product of Asciz is involved in dynein motor functions, including mitotic chromosome segregation, and dynein-independent functions, such as patterning of cell cycles and apoptosis during development. [Date last reviewed: 2019-03-07]
FBgn0035410	MnM	myomesin and myosin binding protein	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0035414	CG14965	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0035415	CG14966	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0035420	hob	hobbit	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0035421	nSMase	neutral sphingomyelinase	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0035422	RpL28	Ribosomal protein L28	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0035423	eIF1	eukaryotic translation initiation factor 1	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0035424	Larp4B	La-related protein 4B	La-related protein 4B (Larp4B) encodes a member of the LARP family of RNA-binding proteins. It has been shown to post-transcriptionally inhibit the expression of the protein encoded by Myc and negatively regulate cell growth. [Date last reviewed: 2021-01-21]
FBgn0035425	CG17746	NA	NA
FBgn0035432	ZnT63C	Zinc transporter 63C	Zinc transporter 63C (ZnT63C) encodes a plasma membrane resident zinc transporter belonging to the zinc transporter family that is mainly responsible for zinc export from the cell or into organelles. It plays a key role in effluxing zinc from enterocytes into circulation during dietary zinc absorption. [Date last reviewed: 2019-03-21]
FBgn0035435	PIG-C	Phosphatidylinositol glycan anchor biosynthesis class C	Phosphatidylinositol glycan anchor biosynthesis class C (PIG-C) encodes a subunit of GPI-GlcNAc transferase, which catalyzes the first reaction in the biosynthesis of the glycosylphosphatidylinositol (GPI)-anchor. [Date last reviewed: 2019-03-14]
FBgn0035437	Strip	Striatin interacting protein	Striatin interacting protein (Strip) encodes an intracellular protein and component of the STRIPAK PP2A protein complex. It is involved in Hippo signaling, endosome maturation, and microtubule regulation. [Date last reviewed: 2019-03-14]
FBgn0035438	PHGPx	PHGPx	PHGPx (PHGPx) encodes a peroxidase involved in intestinal stem cell homeostasis and the response to endoplasmic reticulum stress. [Date last reviewed: 2019-09-12]
FBgn0035439	CG14961	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-10-13]
FBgn0035440	CG14969	NA	NA
FBgn0035443	CG12010	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0035444	CG12012	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0035445	Ids	Iduronate 2-sulfatase	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0035449	CG14971	NA	NA
FBgn0035452	CG10359	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0035461	ntc	nutcracker	NA
FBgn0035462	IntS10	Integrator 10	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0035464	PIG-B	Phosphatidylinositol glycan anchor biosynthesis class B	NA
FBgn0035469	Lamtor4	Late endosomal/lysosomal adaptor, MAPK and MTOR activator 4	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0035470	Ccz1	Caffeine, calcium, zinc sensitivity 1	Caffeine, calcium, zinc sensitivity 1 (Ccz1) encodes a protein that forms a complex with the product of Mon1 and acts as an exchange factor of the small G-protein encoded by Rab7. The Ccz1/Mon1 complex activates and recruits the product of Rab7 to the maturing endosome, where it organizes the fusion of the matured endosome with the lysosome. Ccz1/Mon1 complex loss of function results in Rab7 phenotypes. [Date last reviewed: 2019-03-07]
FBgn0035471	Sc2	Sc2	NA
FBgn0035473	mge	maggie	maggie (mge) encodes a protein predicted to act as a receptor of the TOM (translocase of outer membrane) complex, which is involved in protein import into mitochondria. The product of mge modulates cell death induced by the expression of the mouse Bax protein. [Date last reviewed: 2019-03-14]
FBgn0035475	CG10866	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0035477	CG14982	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-10-13]
FBgn0035480	CG14984	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-10-13]
FBgn0035482	CG14985	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0035483	Mul1	Mitochondrial E3 ubiquitin protein ligase 1	NA
FBgn0035488	CG11593	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-10-13]
FBgn0035496	CG14990	NA	NA
FBgn0035497	CG14995	NA	NA
FBgn0035498	Fit1	Fermitin 1	NA
FBgn0035499	Chd64	Chd64	Chd64 (Chd64) encodes a protein involved in the juvenile hormone mediated signaling pathway. [Date last reviewed: 2019-09-12]
FBgn0035515	CG14997	NA	NA
FBgn0035517	CG1265	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0035518	CG15011	NA	NA
FBgn0035519	CG1309	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0035520	CG11586	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0035523	Ctl1	Choline transporter-like 1	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0035524	CG11583	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0035526	CG1316	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0035528	CG15012	NA	NA
FBgn0035529	Fdx2	Ferredoxin 2	Ferredoxin 2 (Fdx2) encodes a protein involved in ecdysteroid biosynthesis regulation. [Date last reviewed: 2019-09-19]
FBgn0035532	CG15014	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0035533	Cip4	Cdc42-interacting protein 4	Cdc42-interacting protein 4 (Cip4) encodes an F-BAR protein that functions as an adaptor protein regulating membrane curvature and dynamics. [Date last reviewed: 2019-09-12]
FBgn0035534	mRpS6	mitochondrial ribosomal protein S6	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0035540	Syx17	Syntaxin 17	Syntaxin 17 (Syx17) encodes a Qa type SNARE protein localizing to ER, mitochondria and autophagosomes. It mediates the fusion of autophagosomes with endosomes and lysosomes by forming a SNARE complex with the products of Snap29 and Vamp7. The product of Syx17 roles include autophagosome clearance and neuromuscular function. [Date last reviewed: 2019-03-14]
FBgn0035541	CG15019	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0035542	DOR	Diabetes and obesity regulated	Diabetes and obesity regulated (DOR) encodes a transcriptional coactivator of ecdysone receptor signaling required during metamorphosis. It is antagonized by insulin signaling via the product of foxo in the fat body and forms part of a feed-forward mechanism whereby ecdysone potentiates its own signaling. The product of DOR also regulates autophagosome formation and protein degradation via ecdysone signaling. [Date last reviewed: 2019-03-07]
FBgn0035558	CG11357	NA	NA
FBgn0035586	Fitm	Fat storage inducing transmembrane protein	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0035588	Dhrs4	Dehydrogenase/reductase 4	NA
FBgn0035589	CHMP2B	Charged multivesicular body protein 2b	Charged multivesicular body protein 2b (CHMP2B) encodes an ESCRT-III component. It plays an important role in the generation of multivesicular bodies in the endosomal lysosomal pathway. It is also considered to play an important role in autophagosome maturation. [Date last reviewed: 2019-03-07]
FBgn0035590	Tcs5	Threonyl-carbamoyl synthesis 5	Threonyl-carbamoyl synthesis 5 (Tcs5) encodes an atypical Ser/Thr kinase part of the KEOPS/EKC complex. It phosphorylates the product of p53 and is regulated by the products of Akt and Rab35. It is involved in tRNAs modification, telomere and chromatin dynamics. [Date last reviewed: 2019-03-14]
FBgn0035591	CG4611	NA	NA
FBgn0035592	CG10674	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0035593	CG4603	NA	NA
FBgn0035600	Cyt-c1	Cytochrome c1	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0035601	Uev1A	Ubiquitin-conjugating enzyme variant 1A	Ubiquitin-conjugating enzyme variant 1A (Uev1A) encodes a conserved protein that contributes to ubiquitin conjugating enzyme activity, but not catalytically, since it lacks the conserved cysteine residue essential for ubiquitin conjugation. It regulates genomic integrity, IMD pathway-mediated innate immunity, JNK-pathway mediated cell death and tumor invasion. [Date last reviewed: 2019-12-19]
FBgn0035603	Pfdn4	Prefoldin 4	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0035608	blanks	blanks	blanks (blanks) encodes a nuclear siRNA binding protein expressed in spermatocytes. It contributes to sperm individualization and chromatin silencing regulation. [Date last reviewed: 2018-10-18]
FBgn0035617	l(3)psg2	lethal (3) persistent salivary gland 2	NA
FBgn0035622	TM9SF3	Transmembrane 9 superfamily protein member 3	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0035623	mthl2	methuselah-like 2	NA
FBgn0035624	Eaf6	Esa1-associated factor 6	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0035626	lin-28	lin-28	NA
FBgn0035627	Sse	Separase	Separase (Sse) encodes an endoprotease. Together with the product of thr, it forms a complex which cleaves a subunit of the cohesin complex during meiosis, thereby allowing separation of the sister chromatids. [Date last reviewed: 2019-03-14]
FBgn0035630	CG10576	NA	NA
FBgn0035631	Txl	Thioredoxin-like	Thioredoxin-like (Txl) encodes a protein predicted to be involved in the cell redox homeostasis. [Date last reviewed: 2019-09-26]
FBgn0035632	Ppat-Dpck	Bifunctional Phosphopantetheine adenylyltransferase - Dephospho-CoA kinase	Bifunctional Phosphopantetheine adenylyltransferase - Dephospho-CoA kinase (Ppat-Dpck) encodes a bifunctional enzyme that carries out the last two steps of the canonical Coenzyme A (CoA) biosynthesis pathway. The Ppat part converts 4'-phosphopantetheine into dephospho-CoA and subsequently the Dpck part phosphorylates dephospho-CoA to form CoA. [Date last reviewed: 2019-03-14]
FBgn0035639	kri	krishah	krishah (kri) encodes a uracil phosphoribosyltransferase. [Date last reviewed: 2019-09-12]
FBgn0035640	mad2	mad2	mad2 (mad2) encodes a conserved component of the spindle checkpoint. During mitosis, it is recruited to unattached kinetochores, where it binds the products of Mad1 and fzy, promoting the assembly of the mitotic checkpoint complex. During interphase, the product of mad2 is intranuclear, bound to the product of Mad1, and associated primarily with the nuclear pore complex. [Date last reviewed: 2019-03-14]
FBgn0035641	CG5568	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0035642	CG18586	NA	NA
FBgn0035644	PolE2	DNA polymerase epsilon subunit 2	DNA polymerase epsilon subunit 2 (PolE2) encodes a non-catalytic subunit of the major replicative polymerase epsilon. It is involved in the regulation of DNA endoreduplication. [Date last reviewed: 2019-09-19]
FBgn0035670	CG10472	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0035674	CG13295	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0035675	CG6610	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0035678	CG10469	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0035679	CG10467	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0035688	fmt	fiery mountain	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0035689	CG7376	NA	NA
FBgn0035690	CG10274	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0035691	CG7386	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0035692	Sf3b6	Splicing factor 3b subunit 6	NA
FBgn0035702	CG10147	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0035703	Bulli	Bulli	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0035704	Vps8	Vacuolar protein sorting 8	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0035708	axed	axundead	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0035713	velo	veloren	veloren (velo) encodes a SUMO protease that is required for dendrite and axon targeting of olfactory projection neurons. [Date last reviewed: 2018-10-18]
FBgn0035714	Sbds	SBDS ribosome maturation factor	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0035715	Ist1	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0035719	tow	target of wingless	target of wingless (tow) overexpression and genetic interaction studies suggest that it acts downstream of the products of fz/dsh (Planar Cell Polarity pathway) and upstream of the product of smo (Hedgehog pathway) during development. [Date last reviewed: 2019-03-14]
FBgn0035720	CG10077	NA	NA
FBgn0035721	CG9948	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0035722	CG10075	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0035725	Mis12	Mis12	Mis12 (Mis12) encodes a protein involved in chromosome movement and metaphase plate congression during mitosis. [Date last reviewed: 2019-09-26]
FBgn0035726	CG9953	NA	NA
FBgn0035727	CG10063	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0035751	CG14829	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-10-13]
FBgn0035753	RpL18	Ribosomal protein L18	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0035754	MED4	Mediator complex subunit 4	NA
FBgn0035760	CG8607	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0035761	RhoGEF4	Rho guanine nucleotide exchange factor 4	NA
FBgn0035762	Rint1	RAD50 interactor 1	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0035763	mrva	minerva	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0035766	eco	Establishment of cohesion	NA
FBgn0035767	Cln7	Cln7	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0035769	CTCF	CTCF	CTCF (CTCF) encodes a ubiquitous transcription factor that binds to insulators and domain boundaries. It mediates insulator function and blocks enhancers by binding to the product of Cp190. It contributes to long-range chromatin interaction, organizes chromatin domain boundaries and coordinates nuclear architecture. [Date last reviewed: 2019-03-07]
FBgn0035770	pst	pastrel	pastrel (pst) encodes a protein involved in long-term memory and protein secretion. [Date last reviewed: 2019-09-19]
FBgn0035771	Sec63	Secretory 63	NA
FBgn0035772	Sh3beta	Sh3beta	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0035793	CG7546	NA	NA
FBgn0035802	Pura	Puratrophin-1-like	Puratrophin-1-like (Pura) encodes a RhoGEF involved in leg morphogenesis, neuron morphogenesis, and locomotor rhythm regulation. [Date last reviewed: 2019-07-11]
FBgn0035805	CG7506	NA	NA
FBgn0035807	CG7492	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0035811	Mcad	Medium-chain acyl-CoA dehydrogenase	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0035812	CG7457	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0035824	CG8281	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0035825	CG8111	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0035827	Srp9	Signal recognition particle 9	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0035829	HP4	Heterochromatin protein 4	Heterochromatin protein 4 (HP4) encodes a component of classical heterochromatin that is involved in gene silencing by heterochromatin. [Date last reviewed: 2018-10-04]
FBgn0035830	CG8209	NA	NA
FBgn0035831	Pop4	POP4 ribonuclease P/MRP subunit	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0035833	CG7565	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0035838	ldbr	lariat debranching enzyme	NA
FBgn0035839	CG7550	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0035842	Setx	Senataxin	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0035844	CG13676	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0035848	Uxs	UDP-xylose synthase	NA
FBgn0035849	ERR	estrogen-related receptor	estrogen-related receptor (ERR) encodes a protein that directly induces a transcriptional switch in mid-embryogenesis, up-regulating the genes that act in biosynthetic pathways associated with aerobic glycolysis. This nuclear receptor establishes the metabolic state that supports growth during larval stages. [Date last reviewed: 2019-03-07]
FBgn0035850	Atg18a	Autophagy-related 18a	Autophagy-related 18a (Atg18a) encodes a protein that regulates autophagy by participating in isolation membrane elongation around cytoplasmic cargoes. [Date last reviewed: 2019-03-07]
FBgn0035851	MED24	Mediator complex subunit 24	NA
FBgn0035853	UbcE2M	NEDD8-conjugating enzyme UbcE2M	NA
FBgn0035854	CG8005	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0035866	Arl5	ADP-ribosylation factor-like 5	ADP-ribosylation factor-like 5 (Arl5) encodes a protein involved in endosome-to-Golgi trafficking. [Date last reviewed: 2019-08-01]
FBgn0035867	CG13671	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0035868	CG7194	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0035871	BI-1	Bax Inhibitor-1	NA
FBgn0035872	Cpsf6	Cleavage and polyadenylation specific factor 6	NA
FBgn0035876	Pex2	Peroxin 2	Peroxin 2 (Pex2) encodes a peroxisome protein important for sperm development. [Date last reviewed: 2019-03-14]
FBgn0035877	CG7083	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0035878	CG7182	NA	NA
FBgn0035879	GAPcenA	GTPase activating protein and centrosome-associated	NA
FBgn0035880	Culd	CUB and LDLa domain	CUB and LDLa domain (Culd) encodes a photoreceptor-cell enriched transmembrane protein. It localizes to endocytic vesicles and is required for endocytic trafficking of the products of ninaE and trpl. [Date last reviewed: 2018-10-18]
FBgn0035888	CG7120	NA	NA
FBgn0035890	CG13667	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0035896	CG6983	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0035900	ZC3H3	ZC3H3	NA
FBgn0035901	Pus7	Pseudouridine synthase 7	NA
FBgn0035902	CG6683	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-10-13]
FBgn0035903	CG6765	NA	NA
FBgn0035904	GstO3	Glutathione S transferase O3	Glutathione S transferase O3 (GstO3) encodes a transferase involved in glutathione metabolism. [Date last reviewed: 2019-09-19]
FBgn0035906	GstO2	Glutathione S transferase O2	Glutathione S transferase O2 (GstO2) encodes a protein involved in glutathione metabolism. [Date last reviewed: 2019-09-19]
FBgn0035907	GstO1	Glutathione S transferase O1	Glutathione S transferase O1 (GstO1) encodes a transferase involved in glutathione metabolism. [Date last reviewed: 2019-09-19]
FBgn0035909	ergic53	ergic53	NA
FBgn0035911	CG6638	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0035916	GAPsec	GTPase activating protein, SECIS-dependent read-through	GTPase activating protein, SECIS-dependent read-through (GAPsec) encodes GTPase-activating protein involved in translational readthrough. [Date last reviewed: 2019-03-07]
FBgn0035918	Cdc6	Cdc6	Cdc6 (Cdc6) encodes an essential component of the pre-Replication complex (preRC) together with the origin recognition complex, the product of dup and MCM2-7 proteins. The preRC is present at all chromosomal origins of replication and is required for the initiation of DNA replication. The product of Cdc6 also functions in the co-ordination of DNA replication with mitosis, and may contribute to apoptosis and transcription. [Date last reviewed: 2019-03-07]
FBgn0035923	CG6511	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0035942	ValRS-m	Valyl-tRNA synthetase, mitochondrial	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0035944	CG5021	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0035945	CG5026	NA	NA
FBgn0035947	Srp68	Signal recognition particle 68	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0035951	CG5068	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0035953	CG5087	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0035959	CG4911	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0035960	CG4942	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0035964	Dhpr	Dihydropteridine reductase	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0035965	Use1	Unconventional SNARE in the ER 1	NA
FBgn0035968	Slc45-1	Solute carrier family 45 member 1	Solute carrier family 45 member 1 (Slc45-1) encodes a proton/sucrose symporter occuring in apical membranes of the late embryonic hindgut as well as in vesicular membranes of ovarian follicle cells. It may either serve as an osmolyte transporter or be responsible for the resorption of sucrose. [Date last reviewed: 2018-10-18]
FBgn0035975	PGRP-LA	Peptidoglycan recognition protein LA	Peptidoglycan recognition protein LA (PGRP-LA) encodes a protein implicated in the regulation of the immune deficiency pathway in some epithelia. [Date last reviewed: 2019-03-14]
FBgn0035976	PGRP-LC	Peptidoglycan recognition protein LC	Peptidoglycan recognition protein LC (PGRP-LC) encodes a transmembrane receptor involved in the recognition of DAP-type peptidoglycan, a cell wall component found on Gram-negative bacteria and certain Gram positive bacteria. It functions upstream of the immune deficiency pathway. [Date last reviewed: 2019-03-14]
FBgn0035977	PGRP-LF	Peptidoglycan recognition protein LF	Peptidoglycan recognition protein LF (PGRP-LF) encodes a transmembrane receptor that prevents the spontaneous activation of the immune deficiency pathway receptor encoded by PGRP-LC. [Date last reviewed: 2019-03-14]
FBgn0035978	UGP	UDP-glucose pyrophosphorylase	UGP (UGP) encodes an enzyme involved in hyperoxia response. [Date last reviewed: 2019-09-19]
FBgn0035980	mRRF1	mitochondrial ribosome recycling factor 1	NA
FBgn0035981	CG4452	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0035983	CG4080	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0035986	CG4022	NA	NA
FBgn0035987	Cpsf5	Cleavage and polyadenylation specific factor 5	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0035989	Atat	alpha-tubulin acetylase	NA
FBgn0035993	Nf-YA	Nuclear factor Y-box A	Nuclear factor Y-box A (Nf-YA) encodes a subunit of the nuclear transcription factor Y (NF-Y), also known as the CCAAT motif-binding factor (CBF). It is involved in eye and thorax development via gene expression regulation. [Date last reviewed: 2018-10-18]
FBgn0035995	CG3529	NA	NA
FBgn0035996	CG3448	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0035997	phol	pleiohomeotic like	pleiohomeotic like (phol) encodes a zinc-finger protein that is 80% identical in the zinc-finger region to the product of pho. The product of phol plays a role in Polycomb group protein recruitment to Polycomb response elements, but it has additional roles, most likely as a transcriptional activator. [Date last reviewed: 2019-03-14]
FBgn0035998	CG3437	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0035999	CG3552	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0036000	CG3434	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0036004	Jarid2	Jumonji, AT rich interactive domain 2	Jumonji, AT rich interactive domain 2 (Jarid2) encodes a nuclear protein that functions as a DNA-binding transcriptional repressor. It functions as a scaffold for the recruitment of various complexes, including Polycomb repressive complex 2. It is involved in intestinal stem proliferation and differentiation. [Date last reviewed: 2018-10-18]
FBgn0036005	pall	pallbearer	pallbearer (pall) encodes an F-Box protein. In response to apoptosis, it translocates from the nucleus to the cytoplasm of macrophages to promote apoptotic cell clearance by degrading the product of RpS6, and promote actin remodeling through activation of the product of Rac2. [Date last reviewed: 2019-03-14]
FBgn0036007	path	pathetic	NA
FBgn0036008	CG3408	NA	NA
FBgn0036018	CG3335	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0036020	Cyp40	Cyclophilin 40	Cyclophilin 40 (Cyp40) encodes a protein with essential functions in germ cells during sperm maturation. As a co-chaperone of Hsp83, Cyp40 forms complexes with Argonaute (Ago) proteins and small RNA intermediate duplexes, and controls the silencing effector formation by AGO2 in the testis. [Date last reviewed: 2021-01-21]
FBgn0036028	CG16717	NA	NA
FBgn0036030	Prps	Phosphoribosyl pyrophosphate synthetase	NA
FBgn0036032	CG16711	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-10-13]
FBgn0036035	CG18178	NA	NA
FBgn0036036	CG14174	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0036038	defl	deflated	deflated (defl) encodes a component of 'Integrator', a multi-subunit protein complex that binds to the C-terminal domain of RNA polymerase II and is involved in RNA transcript processing and maturation. [Date last reviewed: 2019-03-07]
FBgn0036039	Naa60	N(alpha)-acetyltransferase 60	N(alpha)-acetyltransferase 60 (Naa60) encodes an enzyme that acetylates the cytosolic N terminal methionine of transmembrane proteins. It is associated with intracellular membranes, in particular Golgi membranes, and is essential for normal Golgi organization and chromosome segregation. [Date last reviewed: 2019-09-26]
FBgn0036043	Ae2	Anion exchanger 2	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0036052	CG10809	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0036053	iPLA2-VIA	calcium-independent phospholipase A2 VIA	calcium-independent phospholipase A2 VIA (iPLA2-VIA) encodes a protein that localizes to cytosol and mitochondria involved in repairing oxidized mitochondrial lipids, such as cardiolipin, and thus preventing cytochrome c release. It is partially responsible for cardiolipin depletion and monolysocardiolipin accumulation in Taz-deficient flies, which is a model of Barth syndrome. [Date last reviewed: 2019-03-07]
FBgn0036058	CG6707	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0036059	nudE	nudE	nudE (nudE) encodes a conserved protein that localizes to kinetochores and spindle microtubules. It contributes to the spindle checkpoint, spindle orientation, centrosome behavior and dendrite morphogenesis. [Date last reviewed: 2019-03-14]
FBgn0036063	CG6674	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0036090	CG8009	NA	NA
FBgn0036096	CG8003	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0036099	CG11811	NA	NA
FBgn0036101	NijA	Ninjurin A	Ninjurin A (NijA) encodes a transmembrane protein of the conserved Ninjurin family. It is upregulated in response to injury and infection, suggesting a role in immune or stress responses. When overexpressed the product of NijA causes cell death. [Date last reviewed: 2019-03-14]
FBgn0036104	CG6418	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0036105	Blos4	Biogenesis of lysosome-related organelles complex 1, subunit 4	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0036107	galla-2	galla-2	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0036110	Cpr67Fb	Cuticular protein 67Fb	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0036111	Aps	Aps	Aps (Aps) encodes a diphosphoinositol-polyphosphate diphosphatase that hydrolyses a range of (di)nucleoside polyphosphates. It is involved in glucose and lipid homeostasis. [Date last reviewed: 2019-09-12]
FBgn0036117	CG6321	NA	NA
FBgn0036118	Blos2	Biogenesis of lysosome-related organelles complex 1, subunit 2	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0036121	CG6310	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-10-13]
FBgn0036124	CG7839	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0036126	Irbp18	Inverted repeat binding protein 18 kDa	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0036133	emei	emei	emei (emei) encodes a regulator of calcium levels localized to the endoplasmatic reticulum. Loss of emei synergizes with oncogenic Ras85D to promote tumor growth via JNK-mediated Hippo signaling. [Date last reviewed: 2020-09-24]
FBgn0036134	FoxK	Forkhead box K	Forkhead box K (FoxK) encodes a transcription factor in the Fork Head family. It is a direct target of Dpp/BMP signaling during midgut development, and in turn regulates the homeobox gene lab to determine endoderm differentiation. It also regulates antiviral gene expression. [Date last reviewed: 2019-03-07]
FBgn0036135	mRpL2	mitochondrial ribosomal protein L2	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0036136	Ufd1	Ubiquitin fusion-degradation 1-like	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0036141	wls	wntless	wntless (wls) encodes a multiple-pass transmembrane protein specifically required for the secretion of Wnt proteins. Its roles include growth regulation, cell survival and developmental patterning. [Date last reviewed: 2019-03-21]
FBgn0036142	Adck5	aarF domain containing kinase 5	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0036144	GlcAT-P	Glucuronyltransferase P	NA
FBgn0036147	Plod	procollagen lysyl hydroxylase	procollagen lysyl hydroxylase (Plod) encodes a lysyl dehydrogenase with roles in Collagen IV biosynthesis. It localizes to the endoplasmic reticulum and is required for the secretion Collagen IV from haemocytes and fat body. [Date last reviewed: 2019-03-14]
FBgn0036152	Dyro	Dpt-YFP repressor by overexpression	NA
FBgn0036155	CG6163	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0036159	CG7557	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0036165	chrb	charybde	NA
FBgn0036173	CG7394	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0036180	Duba	Deubiquitinating enzyme A	Deubiquitinating enzyme A (Duba) encodes a de-ubiquitylating enzyme of the OTU-family that cleaves preferentially K11- and K63-linked poly-ubiquitin chains. Its catalytic activity is required for spermatogenesis. [Date last reviewed: 2018-10-18]
FBgn0036181	Muc68Ca	Mucin 68Ca	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0036184	PCID2	PCI domain-containing protein 2	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0036186	CG6071	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0036187	RIOK1	RIO kinase 1	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0036188	Polr3H	RNA polymerase III subunit H	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0036191	Sugb	Sugar baby	Sugar baby (Sugb) encodes a protein that determines lifespan. [Date last reviewed: 2018-10-18]
FBgn0036194	Dph1	Diphthamide biosynthesis 1	NA
FBgn0036196	CG11658	NA	NA
FBgn0036198	crim	crimpled	crimpled (crim) encodes a protein involved in tracheal system development and the localization of septate junction components. [Date last reviewed: 2019-09-19]
FBgn0036199	Bmcp	Bmcp	NA
FBgn0036207	CG10907	NA	NA
FBgn0036210	CG14130	NA	NA
FBgn0036211	CG5946	NA	NA
FBgn0036213	RpL10Ab	Ribosomal protein L10Ab	Ribosomal protein L10Ab (RpL10Ab) is an essential gene during oogenesis that encodes a ribosomal protein of the large ribosome subunit. [Date last reviewed: 2018-10-25]
FBgn0036237	viaf	viral IAP-associated factor	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0036239	Pop2	Pop2	Pop2 (Pop2) encodes a poly(A)-specific ribonuclease involved in translation inhibition. [Date last reviewed: 2019-08-01]
FBgn0036240	CG6928	NA	NA
FBgn0036248	ssp	sunspot	sunspot (ssp) encodes a protein that contributes to Wingless signaling and endoreplication. [Date last reviewed: 2019-07-11]
FBgn0036249	CG11560	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0036254	CG5645	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0036255	Atg12	Autophagy-related 12	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0036257	RhoGAP68F	Rho GTPase activating protein at 68F	Rho GTPase activating protein at 68F (RhoGAP68F) encodes a GTPase activating protein acting upon small Rho-family GTPases involved in epithelial morphogenesis. It localizes to Rab4 recycling endosomes, forms a complex with the product of Rab4 and modulates the transport of Rab4 recycling endosomes back to the cell surface. [Date last reviewed: 2019-03-14]
FBgn0036258	eIF3l	eukaryotic translation initiation factor 3 subunit l	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0036263	thoc6	thoc6	NA
FBgn0036266	Tsen54	tRNA splicing endonuclease subunit 54	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0036271	Pbgs	Porphobilinogen synthase	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0036272	Sms	Spermine synthase	NA
FBgn0036273	INPP5E	Inositol polyphosphate 5-phosphatase E	NA
FBgn0036277	CG10418	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0036279	Ncc69	sodium chloride cotransporter 69	sodium chloride cotransporter 69 (Ncc69) encodes a member of the SLC12 family of Na[+]/K[+]/2Cl[-] cotransporters (NKCC). [Date last reviewed: 2019-03-14]
FBgn0036286	CG10616	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0036288	CG10660	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0036289	CG10657	NA	NA
FBgn0036290	CG10638	NA	NA
FBgn0036291	CG10681	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0036292	CG10646	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0036298	nst	nesthocker	nesthocker (nst) encodes a phospho-acetylglucosamine mutase, an essential enzyme in the biosynthetic pathway of N-Acetylglucosamine (GlcNAc). In the embryo, it is required for normal GlcNAc levels and affects Fibroblast-Growth-Factor signaling. [Date last reviewed: 2019-03-14]
FBgn0036299	Tsf2	Transferrin 2	Transferrin 2 (Tsf2) encodes a protein that requires binding with iron for protein function. It is localised at the paracellular septate junctions in epithelial tissues and is required for junction assembly. Tsf2 mutants show overelongated tracheal tubes. [Date last reviewed: 2019-03-14]
FBgn0036300	Pmm2	Phosphomannomutase type 2	NA
FBgn0036301	CG4069	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0036302	sowah	sosondowah	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0036305	CG10984	NA	NA
FBgn0036306	CG10973	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0036309	Hip1	Huntingtin interacting protein 1	NA
FBgn0036314	Sf3a2	Splicing factor 3a subunit 2	NA
FBgn0036316	nebu	nebulosa	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0036317	CG10948	NA	NA
FBgn0036318	Wbp2	WW domain binding protein 2	WW domain binding protein 2 (Wbp2) encodes a protein that binds to the Hippo pathway component encoded by yki. It has been linked to promotion of tissue growth via the product of yki. [Date last reviewed: 2019-03-21]
FBgn0036331	CR14117	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0036332	Cul6	Cullin 6	NA
FBgn0036333	MICAL-like	MICAL-like	NA
FBgn0036334	CG11267	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0036335	mRpL20	mitochondrial ribosomal protein L20	NA
FBgn0036336	ste14	isoprenylcysteine carboxylmethyltransferase	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0036337	Adk2	Adenosine kinase 2	NA
FBgn0036340	Srrm1	Serine-arginine repetitive matrix 1	SRm160 (SRm160) encodes a conserved RNA-binding protein that participates in the exon junction complex and is involved in pre-mRNA splicing and 3' end formation. It participates in somatic sex determination, cell death, retinal development and the control of circadian rhythm. Direct targets include rl. [Date last reviewed: 2019-03-21]
FBgn0036341	Syx13	Syntaxin 13	Syntaxin 13 (Syx13) encodes a member of the syntaxin family of t-SNAREs that mediate vesicle fusion within cells. It localizes to endosomes and is involved in autophagosome maturation. [Date last reviewed: 2018-10-25]
FBgn0036342	CG11279	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0036353	CG10171	NA	NA
FBgn0036354	Poc1	Proteome of centrioles 1	Proteome of centrioles 1 (Poc1) encodes a cytoplasmic protein located in the sperm giant centriole and proximal centriole-like structure (PCL), which assists in the elongation of the giant centrioles and recruitment of centriolar proteins to the PCL. It contributes to sperm motility and fertility. [Date last reviewed: 2019-03-14]
FBgn0036356	CG10222	NA	NA
FBgn0036365	cmb	combover	combover (cmb) encodes an in vitro substrate of the product of Rho1 that physically interacts with the planar cell polarity (PCP) effector encoded by mwh. It contributes to PCP during wing hair formation. [Date last reviewed: 2019-03-07]
FBgn0036366	JMJD7	Jumonji domain containing 7	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0036368	CG10738	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0036369	CG10089	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0036372	Abp1	Actin binding protein 1	Actin binding protein 1 (Abp1) encodes an F-actin-binding protein. It plays important roles in cytoskeletal functions of both Scar/WAVE- and wasp-mediated Arp2/3 complex activation during synapse formation, bristle formation and eye development. [Date last reviewed: 2018-10-25]
FBgn0036373	Tgi	Tondu-domain-containing Growth Inhibitor	Tondu-domain-containing Growth Inhibitor (Tgi) encodes a protein that interacts with both components of the sd-yki transcriptional complex to inhibit its activity and thus restrict tissue growth. [Date last reviewed: 2019-03-14]
FBgn0036374	Spt20	Spt20	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0036376	Liprin-beta	Liprin-beta	Liprin-β (Liprin-β) encodes an adaptor protein that can interact with the product of Liprin-α. It is required for normal photoreceptor axon targeting and neuromuscular junction development. [Date last reviewed: 2019-03-14]
FBgn0036381	CG8745	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0036386	CG8833	NA	NA
FBgn0036395	CG17361	NA	NA
FBgn0036396	CG17359	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0036397	Nprl3	Nitrogen permease regulator-like 3	Nitrogen permease regulator-like 3 (Nprl3) encodes a component of the highly conserved GAP activity towards rags 1 (GATOR1) complex, which inhibits the product of Tor activity in response to amino acid starvation. The product of Nprl3, as well as the other GATOR1 components encoded by Nprl2 and Iml1, regulates early meiotic progression. [Date last reviewed: 2019-03-14]
FBgn0036398	upSET	upSET	upSET (upSET) encodes a Polycomb/Trithorax-type global transcriptional regulator. It is recruited to active and inducible genes where it restricts chromatin accessibility and histone acetylation to promoter regions. upSET loss produces female sterility. [Date last reviewed: 2019-03-21]
FBgn0036402	CG6650	NA	NA
FBgn0036405	CG6833	NA	NA
FBgn0036406	CG13484	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-10-13]
FBgn0036423	CG3919	NA	NA
FBgn0036428	Gbs-70E	Glycogen binding subunit 70E	Glycogen binding subunit 70E (Gbs-70E) is one of the glycogen binding subunits of protein phosphatase 1 (Pp1) that interacts with all of the known Pp1 catalytic subunits (encoded by Pp1-87B, flw, Pp1α-96A, and Pp1-13C). The product of Gbs-70E is involved in the regulation of glycogen metabolism, and plays a role in the egg development. [Date last reviewed: 2019-03-21]
FBgn0036433	CG9628	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0036446	Mgat4a	alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase a	NA
FBgn0036448	mop	myopic	myopic (mop) encodes an endocytic protein that is required for normal Egfr signaling and for the progression of the product of Egfr through the endocytic pathway. It also controls the endosomal localization and signaling activity of the product of yki. [Date last reviewed: 2019-03-14]
FBgn0036449	bmm	brummer	brummer (bmm) encodes a triglyceride lipase involved in glycerolipid metabolism, regulation of lipid storage and triglyceride homeostasis. [Date last reviewed: 2019-09-12]
FBgn0036450	Tdrd3	Tudor domain containing 3	NA
FBgn0036451	Helz	Helicase with zinc finger	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0036454	CG17839	NA	NA
FBgn0036460	CG5114	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0036462	mRpL39	mitochondrial ribosomal protein L39	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0036463	Reck	Reversion-inducing-cysteine-rich protein with kazal motifs	NA
FBgn0036476	sstn	stepping stone	stepping stone (sstn) encodes an adaptor protein that forms a complex with the plasma membrane encoded by step through direct coil-coil domain interactions. It functions with the product of step to antagonize actomyosin networks during cleavage of the Drosophila embryo. [Date last reviewed: 2019-03-14]
FBgn0036480	Cep135	Centrosomal protein 135kDa	Centrosomal protein 135kDa (Cep135) encodes a microtubule binding protein important for centriole elongation and stability. It promotes centrosome asymmetry and spindle orientation in neuroblasts and it is required for male fertility. [Date last reviewed: 2019-03-07]
FBgn0036483	CG12316	NA	NA
FBgn0036484	Pex3	Peroxin 3	Peroxin 3 (Pex3) encodes a peroxisomal membrane protein (PMP) involved in de novo peroxisome biogenesis from the endoplasmic reticulum and PMP import from the cytosol. It also facilitates the insertion of proteins into the membrane of mature peroxisomes via its interaction with the PMP chaperone encoded by Pex19. [Date last reviewed: 2019-03-14]
FBgn0036486	Msh6	Msh6	Msh6 (Msh6) encodes a heterodimer with the product of spel1 to detect base-base mismatches and small insertion/deletion loops. It then recruits the rest of the mismatch repair machinery. [Date last reviewed: 2019-03-14]
FBgn0036487	Prp31	Pre-mRNA processing factor 31	Pre-mRNA processing factor 31 (Prp31) encodes a splicing factor associated with U4/U6.U5 tri-snRNP. It plays important roles in pre-mRNA splicing and other steps of RNA processing. Prp31 is essential for photoreceptor development. [Date last reviewed: 2019-03-14]
FBgn0036488	CG6878	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0036489	CG7011	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0036493	CG7255	NA	NA
FBgn0036500	CG7275	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0036501	CG7272	NA	NA
FBgn0036502	CG7841	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0036505	CG7945	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0036509	CG7739	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0036510	SCCRO	Squamous cell carcinoma-related oncogene	NA
FBgn0036512	CG16979	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0036514	CG12301	NA	NA
FBgn0036515	AIMP2	aaRS-interacting multifunctional protein 2	aaRS-interacting multifunctional protein 2 (AIMP2) is predicted to encode one of 3 non-enzymatic factors that combine with eight aminoacyl-tRNA synthetases to form a 'multi-synthetase complex' (MSC). The functional significance of the MSC is unclear, but the non-enzymatic factors are thought to be responsive to diverse signal transduction pathways. [Date last reviewed: 2019-03-07]
FBgn0036516	CG7656	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0036518	RhoGAP71E	Rho GTPase activating protein at 71E	Rho GTPase activating protein at 71E (RhoGAP71E) encodes a Rho GTPase activating protein that is involved in the regulation of actin dynamics during epithelial morphogenesis. [Date last reviewed: 2019-08-01]
FBgn0036519	CG7650	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0036522	Phs	Phaser	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0036534	DCP2	Decapping protein 2	Decapping protein 2 (DCP2) encodes a m7G(5')pppN diphosphatase involved in gene silencing by miRNA and the regulation of cytoplasmic mRNA processing body assembly. [Date last reviewed: 2019-09-12]
FBgn0036536	CG12713	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0036537	CG18081	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0036538	CG15715	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0036545	GXIVsPLA2	GXIVsPLA2	NA
FBgn0036549	CG10516	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0036551	CG17029	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0036556	hzg	herzog	NA
FBgn0036557	mRpS31	mitochondrial ribosomal protein S31	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0036565	CG5235	NA	NA
FBgn0036566	ClC-c	Chloride channel-c	Chloride channel-c (ClC-c) encodes an intracellular chloride transporter that is involved in endosomal lumen acidification. [Date last reviewed: 2018-10-25]
FBgn0036567	CG13074	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0036568	ATPsynbetaL	ATP synthase, beta subunit-like	NA
FBgn0036569	IleRS-m	Isoleucyl-tRNA synthetase, mitochondrial	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0036570	IntS9	Integrator 9	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0036571	Strump	Strumpellin	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0036574	elg1	enhanced level of genomic instability 1	NA
FBgn0036576	CG5151	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0036579	CG5027	NA	NA
FBgn0036580	PDCD-5	Programmed Cell Death 5	NA
FBgn0036581	MED10	Mediator complex subunit 10	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0036614	Golgin104	Golgin 104	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0036620	CG4842	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0036621	roq	roquin	NA
FBgn0036622	Agpat4	1-Acylglycerol-3-phosphate O-acyltransferase 4	NA
FBgn0036623	Agpat3	1-Acylglycerol-3-phosphate O-acyltransferase 3	NA
FBgn0036624	RAF2	RING-associated factor 2	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0036629	GluRS-m	Glutamyl-tRNA synthetase, mitochondrial	NA
FBgn0036640	nxf2	nuclear RNA export factor 2	NA
FBgn0036641	Smn	survival motor neuron	survival motor neuron (Smn) encodes the eponymous member of the SMN complex, which functions as an assembly chaperone for Sm-class small nuclear ribonucleoproteins. The SMN complex contains three other 'Gemin' proteins encoded by Gem2, Gem3 and rig. Smn is essential for viability but higher levels of the protein are required for proper neuromuscular development and function. [Date last reviewed: 2019-03-14]
FBgn0036643	Syx8	Syntaxin 8	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0036646	CR18217	NA	NA
FBgn0036648	CG4098	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0036661	CG9705	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0036662	CG9706	NA	NA
FBgn0036663	CG9674	NA	NA
FBgn0036666	TSG101	Tumor susceptibility gene 101	Tumor susceptibility gene 101 (TSG101) encodes an ESCRT-I complex component that acts as an adapter for membrane rearrangements operated by ESCRT-III. Its roles include endosomal sorting of ubiquitinated cargoes, which is important for signaling regulation, cytokinesis, and budding of viruses and exovesicles. [Date last reviewed: 2019-03-14]
FBgn0036667	kud	kuduk	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0036668	Zcchc7	Zinc finger CCHC-type containing 7	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0036671	CG9951	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0036684	CG3764	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0036685	CG6664	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0036686	CG7728	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0036688	Fit2	Fermitin 2	NA
FBgn0036689	CG7730	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0036691	beg	bad egg	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0036695	Papst2	PAPS transporter 2	PAPS transporter 2 (Papst2) encodes the second transporter of 3'-phosphoadenosine 5'-phosphosulfate (PAPS) and localizes in the cis-cisterna of the Golgi and the ER. It transfers PAPS from cytosol into the lumen of Golgi and ER. The product of Papst2 contributes to the sulfation of glycans and proteins, and is suggested to regulate several signaling pathways (Hh, Dpp, Wingless) mediated by glycosaminoglycans in development. [Date last reviewed: 2019-03-14]
FBgn0036696	Pop5	POP5 ribonuclease P/MRP subunit	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0036697	rogdi	rogdi	rogdi (rogdi) encodes a protein that plays a role in promoting sleep by controlling GABA transmission in GABA neurons. [Date last reviewed: 2018-10-25]
FBgn0036702	Afg3l2	AFG3 like matrix AAA peptidase subunit 2	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0036710	CG6479	NA	NA
FBgn0036714	CG7692	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0036726	QIL1	QIL1	QIL1 (QIL1) encodes a subunit of the mitochondrial contact site and cristae organizing system (MICOS) complex. It is required for MICOS stability regulating mitochondrial cristae architecture. [Date last reviewed: 2019-03-14]
FBgn0036728	UQCR-Q	Ubiquinol-cytochrome c reductase ubiquinone-binding protein	NA
FBgn0036732	Oatp74D	Organic anion transporting polypeptide 74D	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0036733	U4-U6-60K	U4-U6 small nuclear riboprotein factor 60K	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0036734	CG7564	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0036735	Edc3	Enhancer of decapping 3	NA
FBgn0036740	Vps60	Vacuolar protein sorting 60	Vacuolar protein sorting 60 (Vps60) encodes a member of the Vps4 complex. It contributes to the formation of intraluminal vesicles and multi-vesicular bodies by supporting the dissociation of the ESCRT complex from the invaginating membranes on endosomes. [Date last reviewed: 2019-03-21]
FBgn0036741	anchor	anchor	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0036745	CG7484	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0036746	Crtc	CREB-regulated transcription coactivator	CREB-regulated transcription coactivator (Crtc) encodes a highly conserved transcriptional coactivator of cAMP-response element-binding protein (CREB). Its nuclear localization is regulated by several factors including intracellular cAMP or calcium levels, or calcineurin. Sik family kinases also phosphorylate to inhibit the product of Crtc and, consequently, control energy homeostais and lipid metabolism. [Date last reviewed: 2019-03-07]
FBgn0036749	CG7460	NA	NA
FBgn0036752	Adgf-A	Adenosine deaminase-related growth factor A	Adenosine deaminase-related growth factor A (Adgf-A) encodes an extracellular deaminase that regulates the level of extracellular adenosine by converting adenosine to inosine. This activity is important for regulation of systemic metabolism, especially during stress and infection. [Date last reviewed: 2019-03-07]
FBgn0036754	CG5589	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0036759	CG5577	NA	NA
FBgn0036760	CG5567	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0036761	MED19	Mediator complex subunit 19	Mediator complex subunit 19 (MED19) encodes a conserved nuclear protein that acts as a hinge in the flexible mediator transcription complex associated with RNA polymerase II. [Date last reviewed: 2019-03-14]
FBgn0036762	CG7430	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0036763	TrpRS-m	Tryptophanyl-tRNA synthetase, mitochondrial	Tryptophanyl-tRNA synthetase, mitochondrial (TrpRS-m) encodes a protein predicted to function within mitochondria to catalyze the ligation of tryptophan to its cognate tRNA to form tryptophanyl-tRNA. [Date last reviewed: 2019-03-14]
FBgn0036764	CG5535	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0036765	CG7408	NA	NA
FBgn0036770	Prestin	Prestin	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0036771	Wdr92	WD repeat domain 92	NA
FBgn0036772	CG5290	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0036774	mRpS26	mitochondrial ribosomal protein S26	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0036775	Polr3D	RNA polymerase III subunit D	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0036777	CG7341	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0036801	MYPT-75D	Myosin phosphatase targeting subunit 75D	Myosin phosphatase targeting subunit 75D (MYPT-75D) encodes a protein phosphatase 1 binding protein involved in myosin phosphatase regulation. [Date last reviewed: 2019-09-26]
FBgn0036804	Sgf11	SAGA associated factor 11kDa	SAGA associated factor 11kDa (Sgf11) encodes a component of the highly conserved Spt-Ada-Gcn5 Acetyltransferase (SAGA) chromatin modifying complex. This complex is responsible for acetylation of histones and deubiquitination of the product of His2B at active promoters. The product of Sgf11 is a component of the deubiquitinase module, interacts with the non-stop deubiquitinase, and is essential for non-stop enzymatic activity in vitro. [Date last reviewed: 2019-03-14]
FBgn0036805	Chmp1	Charged multivesicular body protein 1	Charged multivesicular body protein 1 (Chmp1) encodes a component of ESCRT-III, a conserved protein complex that mediates downregulation of activated transmembrane receptors through formation of the multivesicular body from the endosome. It binds to the product of Vps4, promoting the dissociation and recycling of ESCRT-III components to the cytoplasm. [Date last reviewed: 2018-10-25]
FBgn0036806	Cyp12c1	Cytochrome P450 12c1	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0036811	MED11	Mediator complex subunit 11	NA
FBgn0036812	Nufip	Nufip	Nufip (Nufip) encodes an adaptor protein for the assembly of RiboNucleo-Particles (RNPs) such as the small nuclear RNP U4 (snRNP U4; part of the spliceosome) and the mRNPs encoding seleno-proteins. It is necessary for the biogenesis of the small nucleolar RNPs (snoRNPs). [Date last reviewed: 2019-03-14]
FBgn0036813	Atg3	Autophagy-related 3	Autophagy-related 3 (Atg3) encodes a protein involved in multiple autophagy processes such as autophagosome assembly, cellular response to starvation, and glycophagy. [Date last reviewed: 2019-06-27]
FBgn0036814	CG14073	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0036815	HipHop	HP1-HOAP-interacting protein	HP1-HOAP-interacting protein (HipHop) encodes a protein that interacts with the products of cav and Su(var)205. It is involved in telomere capping. [Date last reviewed: 2019-09-19]
FBgn0036816	Indy	I'm not dead yet	I'm not dead yet (Indy) encodes a plasma membrane transporter of Krebs cycle intermediates (citrate, succinate, fumarate, alpha-ketoglutarate) of the SLC13A family that is important in organismal intermediary metabolism. Mutations in Indy create a favorable metabolic state, similar to calorie restriction, and extend life span. [Date last reviewed: 2019-03-07]
FBgn0036817	CG6865	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0036818	CG14074	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0036819	Dysb	Dysbindin	NA
FBgn0036820	Grx1	Glutaredoxin 1	Glutaredoxin 1 (Grx1) encodes a protein involved in copper ion homeostasis. [Date last reviewed: 2019-09-19]
FBgn0036821	CG3961	NA	NA
FBgn0036824	CG3902	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0036825	RpL26	Ribosomal protein L26	Ribosomal protein L26 (RpL26) encodes a protein component of large ribosomal subunits. [Date last reviewed: 2018-10-25]
FBgn0036826	arx	asterix	asterix (arx) encodes a nuclear protein required for fertility. It plays an essential role in piRNA-guided transcriptional silencing, interacting probably directly with the product of piwi. [Date last reviewed: 2019-03-07]
FBgn0036827	CG6843	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0036828	Prp6	pre-mRNA processing factor 6	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0036837	CG18135	NA	NA
FBgn0036838	CG3808	NA	NA
FBgn0036842	Ugt316A1	UDP-glycosyltransferase family 316 member A1	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0036843	Sfxn2	Sideroflexin 2	NA
FBgn0036844	Mkp3	Mitogen-activated protein kinase phosphatase 3	Mitogen-activated protein kinase phosphatase 3 (Mkp3) encodes a member of the mitogen-activated protein kinase phosphatases that inactivate MAPKs. It dephosphorylates the phosphorylated active forms of the products of p38a and rl. [Date last reviewed: 2019-03-14]
FBgn0036846	MESR6	Misexpression suppressor of ras 6	NA
FBgn0036847	CNPYb	Canopy b	NA
FBgn0036848	Naxd	NAD(P)HX dehydratase	NA
FBgn0036849	CG14079	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0036850	Gem2	Gemin 2	Gemin 2 (Gem2) encodes a member of the SMN-Gemins complex and a component of the cytoplasmic U snRNP body. It is required in the motor system for viability and motor behaviour. [Date last reviewed: 2019-09-26]
FBgn0036853	mRpL21	mitochondrial ribosomal protein L21	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0036857	Aldh7A1	Aldehyde dehydrogenase 7 family member A1	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0036862	Gbs-76A	Glycogen binding subunit 76A	NA
FBgn0036886	CG9300	NA	NA
FBgn0036887	CG9231	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0036888	CG9330	NA	NA
FBgn0036889	CG14100	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0036891	CG9372	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0036892	Lon	Lon protease	Lon protease (Lon) encodes a conserved ATP-stimulated serine protease. It is encoded in the nucleus and targeted to the mitochondrial matrix, where it contributes to mitochondrial protein turnover. [Date last reviewed: 2018-10-25]
FBgn0036893	PIG-F	Phosphatidylinositol glycan anchor biosynthesis class F	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0036896	wnd	wallenda	wallenda (wnd) encodes a kinase in the mixed lineage family of MAP Kinase Kinase Kinases. Its roles include axonal injury signaling (it becomes activated in neurons after axotomy), and in regulation of the structure of presynaptic boutons. [Date last reviewed: 2019-03-21]
FBgn0036897	Rnf146	Ring finger protein 146	NA
FBgn0036900	CG8765	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0036906	CG14102	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0036908	TORIP	Torsin interacting protein	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0036909	Ccdc58	Coiled-coil domain-containing 58	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0036911	Fibp	Fibp	NA
FBgn0036913	Usp32	Ubiquitin specific protease 32	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0036915	Prp3	Precursor RNA processing 3	Precursor RNA processing 3 (Prp3) encodes a protein that regulates chromatin silencing. [Date last reviewed: 2019-08-01]
FBgn0036916	Mtr3	Mtr3	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0036918	Pfdn6	Prefoldin 6	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0036919	Grasp65	Grasp65	Grasp65 (Grasp65) encodes a myristoylated Golgi protein that binds the product of GM130 and has been shown to mediate the Golgi bypass of transmembrane proteins. [Date last reviewed: 2019-03-07]
FBgn0036920	CG8004	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0036921	RhoGDI	RhoGDI	NA
FBgn0036922	CG14182	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0036926	CG7646	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0036927	Gabat	gamma-aminobutyric acid transaminase	γ-aminobutyric acid transaminase (Gabat) encodes an enzyme involved in the breakdown of the sleep-promoting neurotransmitter γ-aminobutyric (GABA). It functions in mitochondria, in a shunt of the TCA cycle, and is implicated in the regulation of sleep as well as in metabolism. [Date last reviewed: 2018-10-25]
FBgn0036928	Tom20	Translocase of outer membrane 20	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0036929	CG7668	NA	NA
FBgn0036931	CG14183	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0036932	Lamtor1	Late endosomal/lysosomal adaptor, MAPK and MTOR activator 1	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0036945	Ssk	Snakeskin	NA
FBgn0036958	CG17233	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0036964	FRG1	FSHD region gene 1	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0036967	SCCRO4	Squamous cell carcinoma-related oncogene 4	Squamous cell carcinoma-related oncogene 4 (SCCRO4) encodes a protein involved in the regulation of protein neddylation. [Date last reviewed: 2019-09-19]
FBgn0036973	Rbbp5	Retinoblastoma binding protein 5	NA
FBgn0036974	eRF1	eukaryotic translation release factor 1	NA
FBgn0036975	CG5618	NA	NA
FBgn0036980	RhoBTB	Rho-related BTB domain containing	Rho-related BTB domain containing (RhoBTB) encodes a protein involved in anti-parasitoid immune response. [Date last reviewed: 2019-08-01]
FBgn0036984	CG13248	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0036985	zye	zye	NA
FBgn0036987	CG5274	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0036988	CG5262	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0036990	mRpL15	mitochondrial ribosomal protein L15	NA
FBgn0036991	CtIP	CTBP-interacting protein	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0036994	CG5199	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0036997	CG5955	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0036998	CG5969	NA	NA
FBgn0036999	isoQC	iso Glutaminyl cyclase	iso Glutaminyl cyclase (isoQC) encodes a glutaminyl-peptide cyclotransferase involved in peptidyl-pyroglutamic acid biosynthesis. [Date last reviewed: 2019-09-12]
FBgn0037000	ZnT77C	Zinc transporter 77C	Zinc transporter 77C (ZnT77C) encodes a protein involved in zinc detoxification and zinc transmembrane import. [Date last reviewed: 2019-09-12]
FBgn0037001	ND-39	NADH dehydrogenase (ubiquinone) 39 kDa subunit	NADH dehydrogenase (ubiquinone) 39 kDa subunit (ND-39) encodes a subunit of mitochondrial respiratory complex I (cI, NADH:ubiquinone oxidoreductase). [Date last reviewed: 2019-09-26]
FBgn0037007	BNIP3	NA	NA
FBgn0037008	mTerf3	mitochondrial transcription termination factor 3	NA
FBgn0037009	CG5104	NA	NA
FBgn0037011	CG4858	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0037012	Rcd2	Reduction in Cnn dots 2	NA
FBgn0037016	CG13252	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-10-13]
FBgn0037018	CG4042	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0037019	Pex16	Peroxin 16	Peroxin 16 (Pex16) encodes a protein involved in peroxisome organization, spermatocyte division, and fatty acid catabolism. [Date last reviewed: 2019-08-01]
FBgn0037020	Pex14	Peroxin 14	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0037021	Pcif1	Phosphorylated CTD-interacting factor 1	NA
FBgn0037022	CG11396	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0037024	tzn	tenzing norgay	NA
FBgn0037025	Spc105R	Spc105-related	Spc105-related (Spc105R) encodes an essential component of the kinetochore, to which it is recruited by binding to the Mis12 kinetochore complex. The products of Spc105R and Mis12 recruit the Ndc80 complex, which provides the major microtubule binding activity of the kinetochore. [Date last reviewed: 2019-03-14]
FBgn0037026	CG3634	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0037027	HIPP1	HP1 and insulator partner protein 1	HP1 and insulator partner protein 1 (HIPP1) encodes a chromatin-associated protein, displaying strong protein-protein interaction with the product of Su(var)205. It is localized to pericentric heterochromatin, and potentially has a separate role bound to insulators along with the products of su(Hw), mod(mdg4) and Cp190. [Date last reviewed: 2018-10-25]
FBgn0037028	CG3618	NA	NA
FBgn0037031	CG11456	NA	NA
FBgn0037044	Pdss2	Decaprenyl diphosphate synthase subunit 2	NA
FBgn0037045	CG10584	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0037050	ICA69	Islet cell autoantigen 69 kDa	Islet cell autoantigen 69 kDa (ICA69) encodes a protein that belongs to the BAR (Bin-Amphiphysin-Rvs) family of proteins. It regulates ionotropic glutamate receptor clustering at the neuromuscular junctions and controls synapse morphogenesis through a pathway that involves Spectrin and the product of Rab2. [Date last reviewed: 2018-10-25]
FBgn0037051	CG10565	NA	NA
FBgn0037057	CG10512	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0037061	Trmt112	tRNA methyltransferase subunit 11-2	NA
FBgn0037063	CG9391	NA	NA
FBgn0037070	CG11309	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0037071	CG7632	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0037073	Tsr1	Tsr1 ribosome assembly factor	NA
FBgn0037074	Tbc1d8-9	TBC1 domain family member 8/9	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0037076	ebd2	earthbound 2	earthbound 2 (ebd2) encodes a transcription cofactor with similar roles to the product of ebd1. It functions in the Wingless/Wnt pathway where it promotes the interaction of the products of arm and pan, and the recruitment of the product of arm to chromatin. The product of ebd2 functions in a context-specific manner and is important for the development of indirect flight muscles. [Date last reviewed: 2019-03-07]
FBgn0037081	barc	barricade	NA
FBgn0037082	CG5664	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0037084	Syx6	Syntaxin 6	NA
FBgn0037087	CG7519	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0037092	M6	M6	M6 (M6) encodes a four-transmembrane glycoprotein involved in eye morphogenesis and oogenesis. [Date last reviewed: 2019-09-26]
FBgn0037093	Cdk12	Cyclin-dependent kinase 12	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0037094	CG7611	NA	NA
FBgn0037098	Wnk	Wnk kinase	Wnk kinase (Wnk) encodes a chloride-sensitive Ser/Thr kinase that signals through a downstream target Ser/Thr kinase, encoded by fray, which is activated by phosphorylation the product of Wnk. Its roles include regulation of ion transport and cell growth, and differentiation and developmental patterning, including roles in canonical Wnt signaling and induction of the product of Awh. [Date last reviewed: 2019-03-21]
FBgn0037102	CRIF	CR6-interacting factor	CR6-interacting factor (CRIF) encodes a protein that may play a role in regulating the RNAi pathway by stabilizing the RNAase III enzyme encoded by Dcr-2. [Date last reviewed: 2019-03-07]
FBgn0037105	S1P	Site-1 protease	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0037106	CG11307	NA	NA
FBgn0037108	Alg11	ALG11, alpha-1,2-mannosyltransferase	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0037109	MED1	Mediator complex subunit 1	NA
FBgn0037110	ORMDL	Orosomucoid 1-like	NA
FBgn0037116	Als2	Amyotrophic lateral sclerosis 2	Amyotrophic lateral sclerosis 2 (Als2) encodes a protein which when mutated results in age-dependent locomotion defects. [Date last reviewed: 2019-03-07]
FBgn0037117	CG11248	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0037120	CG11247	NA	NA
FBgn0037121	Polr2H	RNA polymerase II, I and III subunit H	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0037126	CG14567	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0037130	Syn1	Syntrophin-like 1	Syntrophin-like 1 (Syn1) encodes an adaptor protein associated with the Dystrophin glycoprotein complex that recruits different signaling components, including the product of Nos in neurons. Dystrophin-Syn1-neuronal Nos signaling via histone modifications regulates gene expression, including expression of miRNAs, and adapts cellular homeostasis, which is compromised under stress and dystrophic conditions. [Date last reviewed: 2019-03-21]
FBgn0037134	CG7407	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-10-13]
FBgn0037135	CG7414	NA	NA
FBgn0037137	Nopp140	Nopp140	Nopp140 (Nopp140) encodes a nucleolar and Cajal body protein. It is predicted to function as a chaperone in the assembly of small nucleolar ribonucleoprotein particles within Cajal bodies, their transit to nucleoli, and their association with pre-ribosomal RNA within nucleolar dense fibrillar regions. [Date last reviewed: 2019-03-14]
FBgn0037138	P5CDh1	delta-1-Pyrroline-5-carboxylate dehydrogenase 1	delta-1-Pyrroline-5-carboxylate dehydrogenase 1 (P5CDh1) encodes a conserved, nuclear-encoded mitochondrial matrix enzyme. It is a member of the aldehyde dehydrogenase superfamily involved in proline degradation. [Date last reviewed: 2019-03-14]
FBgn0037141	PolH	DNA polymerase eta	DNA polymerase eta (PolH) encodes a member of the Y-family of DNA translesion polymerases. It operates during the bypass of UV-induced lesions and possibly during homologous recombination repair of DNA double-strand breaks. [Date last reviewed: 2019-09-26]
FBgn0037142	CG14562	NA	NA
FBgn0037144	CG7458	NA	NA
FBgn0037149	CG14561	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0037150	CG7133	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0037151	CG7130	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0037153	olf413	olf413	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0037156	CG11523	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0037182	ArfGAP3	ADP-ribosylation factor GTPase activating protein 3	ADP-ribosylation factor GTPase activating protein 3 (ArfGAP3) a GTPase activating proteins for Arf family GTPases. Arf proteins regulate actin dynamics, cell shape, and cell positioning within epithelia such as the eye. [Date last reviewed: 2019-03-07]
FBgn0037183	CG14451	NA	NA
FBgn0037184	CG14450	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0037185	CG11367	NA	NA
FBgn0037188	CG7369	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0037199	EMC4	ER membrane protein complex subunit 4	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0037200	CG11109	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0037202	Ssl1	Suppressor of stem-loop mutation	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0037203	slif	slimfast	NA
FBgn0037205	BoYb	Brother of Yb	Brother of Yb (BoYb) encodes a putative RNA helicase in the TDRD12 family and is predicted to have a role in piRNA biogenesis, specifically in ovarian germline cells. [Date last reviewed: 2019-03-07]
FBgn0037206	CG12768	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0037207	Mes2	Mesoderm-expressed 2	Mesoderm-expressed 2 (Mes2) encodes a transcription regulator involved in ecdysis. [Date last reviewed: 2019-09-12]
FBgn0037213	CG12581	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0037215	beta-Man	beta-Mannosidase	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0037217	CG14636	NA	NA
FBgn0037218	aux	auxilin	auxilin (aux) encodes a co-factor for the ATPase Hsc70 that regulates Clathrin dynamics. It regulates Notch signaling, eye morphogenesis, sperm individualization and neuron death. [Date last reviewed: 2019-03-07]
FBgn0037220	CG14641	NA	NA
FBgn0037222	CG14642	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0037223	TwdlU	TweedleU	NA
FBgn0037225	TwdlG	TweedleG	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0037228	CG1092	NA	NA
FBgn0037229	CG9766	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0037231	Vps24	Vacuolar protein sorting 24	Vacuolar protein sorting 24 (Vps24) encodes an essential subunit of ESCRT-III, one of the endosomal sorting complexes required for transport (ESCRT). It is involved in membrane remodeling in diverse cellular processes, such as multi-vesicular body biogenesis, cytokinesis and virus budding. [Date last reviewed: 2019-03-21]
FBgn0037232	Suv3	Suv3 helicase	NA
FBgn0037234	CG9795	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0037235	CG1103	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0037236	Skp2	S-phase kinase-associated protein 2	S-phase kinase-associated protein 2 (Skp2) encodes the substrate recognizing component of the SCF-Skp2 ubiquitin ligase. It functions with the product of Cks85A to target the product of dap for destruction. It is required for larval growth and to maintain diploidy in imaginal tissues. [Date last reviewed: 2019-03-14]
FBgn0037239	Sfxn1-3	Sideroflexin 1/3	NA
FBgn0037240	Cont	Contactin	Contactin (Cont) encodes a GPI-anchored cell adhesion molecule. It interacts with the product of Nrx-IV in cis to organize septate junctions in epithelial cells and also between ensheathing glial cells and neurons. [Date last reviewed: 2019-03-07]
FBgn0037241	CG14646	NA	NA
FBgn0037242	CG9855	NA	NA
FBgn0037244	CG14647	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0037248	srl	spargel	NA
FBgn0037249	eIF3a	eukaryotic translation initiation factor 3 subunit a	NA
FBgn0037250	CG1074	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0037251	CG9804	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0037252	CG14650	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0037255	Fip1	Factor interacting with poly(A) polymerase 1	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0037261	CG9775	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0037262	MED31	Mediator complex subunit 31	NA
FBgn0037265	spartin	spartin	spartin (spartin) encodes a multi-functional protein associated with organelle membranes, including endosomes, lipid droplets, and mitochondria. It participates in cytokinesis, BMP receptor trafficking, lipid droplet turnover, and mitochondrial Ca[2+] homeostasis. [Date last reviewed: 2019-03-14]
FBgn0037270	eIF3f1	eukaryotic translation initiation factor 3 subunit f1	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0037279	CG1129	NA	NA
FBgn0037282	CG14657	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0037290	CG1124	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0037293	RabGGTa	Rab geranylgeranyltransferase subunit alpha	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0037297	CG1116	NA	NA
FBgn0037298	Sccpdh1	Saccheropin dehydrogenase 1	NA
FBgn0037299	Vps37B	Vacuolar protein sorting 37B	NA
FBgn0037301	Mms19	Mms19	NA
FBgn0037305	CG12173	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0037312	CG11999	NA	NA
FBgn0037313	CG1161	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0037315	Cerk	Ceramide kinase	Ceramide kinase (Cerk) encodes a protein that catalyzes phosphorylation of ceramide, helping to maintain ceramide levels, which in turn regulates photoreceptor structure and function. It is also a component of WntD signaling and mediates primordial germ cell migration. [Date last reviewed: 2019-03-07]
FBgn0037317	CG14667	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0037327	PEK	pancreatic eIF-2alpha kinase	pancreatic eIF-2α kinase (PEK) encodes an endoplasmic reticulum (ER) transmembrane kinase and a component of the integrated stress response. During ER stress the product of PEK phosphorylates the translation initiation factor encoded by eIF2α resulting in the inhibition of most cap-dependent translation. This is especially important during the development of secretory tissues and the response to cellular stress. [Date last reviewed: 2019-03-14]
FBgn0037328	RpL35A	Ribosomal protein L35A	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0037329	POLDIP2	Polymerase (DNA-directed), delta interacting protein 2	NA
FBgn0037330	mRpL44	mitochondrial ribosomal protein L44	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0037332	Hcs	Holocarboxylase synthetase	Holocarboxylase synthetase (Hcs) encodes a biotin protein ligase that contributes to gluconeogenesis, fatty acid synthesis and amino acid catabolism. [Date last reviewed: 2019-03-07]
FBgn0037336	CG2519	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-10-13]
FBgn0037338	Snm1	Snm1	NA
FBgn0037339	Pi4KIIalpha	Phosphatidylinositol 4-kinase II alpha	Pi4KIIα (Pi4KIIα) encodes a lipid kinase that synthesizes phosphatidylinositol 4-phosphate from phosphatidylinositol. It contributes to membrane trafficking in the larval salivary gland. [Date last reviewed: 2019-03-14]
FBgn0037340	CG14671	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-10-13]
FBgn0037341	CG12746	NA	NA
FBgn0037342	CG2931	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0037344	CG2926	NA	NA
FBgn0037345	PolZ2	DNA polymerase zeta subunit 2	NA
FBgn0037347	SecS	Sec synthetase	NA
FBgn0037350	Dph4	Diphthamide biosynthesis 4	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-10-13]
FBgn0037351	RpL13A	Ribosomal protein L13A	Ribosomal protein L13A (RpL13A) encodes a component of the large ribosomal subunit, and thus involved in mRNA translation. Mutations in genes encoding ribosomal proteins affect fertility, viability and other Drosophila phenotypes, described as Minute. [Date last reviewed: 2019-03-14]
FBgn0037354	CG12171	NA	NA
FBgn0037356	CG12170	NA	NA
FBgn0037358	elm	ethanol sensitive with low memory	NA
FBgn0037359	MED27	Mediator complex subunit 27	NA
FBgn0037360	CG2182	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0037363	Atg17	Autophagy-related 17	Autophagy-related 17 (Atg17) encodes a subunit of the evolutionarily conserved Atg1 kinase complex, which controls the initiation of autophagosome formation. The product of Atg17 also has a role in maintaining neuromuscular function and normal lifespan. [Date last reviewed: 2019-03-07]
FBgn0037364	Rab23	Rab23	Rab23 (Rab23) encodes a member of the Rab family of small GTPases known to be involved in vesicle transport processes. It cooperates with the product of in and the core group of planar cell polarity genes. It contributes to restricting actin accumulation and thus, prehair initiation to a single site within each wing cell, and to regulate the number and orientation of hairs on the leg and the abdominal cuticle. In addition, it regulates the trafficking of the ligand encoded by hh in the germline stem cell niche. [Date last reviewed: 2019-03-21]
FBgn0037368	CG1239	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0037369	CG2100	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0037370	CG1236	NA	NA
FBgn0037371	Sym	Symplekin	Symplekin (Sym) encodes a large protein that contains many protein interaction sites, and acts as a scaffold for protein complexes in the nucleus. It functions in RNA 3' end formation for both polyadenyated mRNAs and non-polyadenylated histone mRNAs. In some cells it also localizes to the cell cortex, especially the tricellular junctions of some epithelia. [Date last reviewed: 2018-10-25]
FBgn0037372	CG2091	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0037374	jagn	jagunal	jagunal (jagn) encodes a conserved protein that is located in the endoplasmic reticulum membrane. It contributes to oocyte growth by organizing the endoplasmic reticulum. It is also involved in bristle growth. [Date last reviewed: 2019-03-07]
FBgn0037375	kat-60L1	katanin p60-like 1	katanin p60-like 1 (kat-60L1) encodes a microtubule-severing protein that regulates dendrite morphogenesis. [Date last reviewed: 2019-03-14]
FBgn0037376	Hat1	Histone acetyltransferase 1	Histone acetyltransferase 1 (Hat1) encodes a B-type histone acetyltransferase that localizes to both the cytoplasm and the nucleus. It is involved in the escort machinery of newly synthesized histones encoded by His3 and His4 to chromatin and acetylates the product of His4 at lysines 5 and 12. It also forms a complex with centromeric histone encoded by cid and is involved in cid chromatin assembly. [Date last reviewed: 2019-03-21]
FBgn0037377	CG1218	NA	NA
FBgn0037378	PSMG1	Proteasome assembly chaperone 1	NA
FBgn0037379	CG10979	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0037382	Hpr1	Hpr1	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0037383	Sec20	Secretory 20	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0037384	dgrn	degringolade	degringolade (dgrn) encodes a SUMO-Targeted ubiquitin ligase. During development it is required for Notch signaling and patterning. It contributes to transcriptional regulation, DNA repair, and cytoskeleton dynamics. [Date last reviewed: 2019-03-07]
FBgn0037391	CG2017	NA	NA
FBgn0037405	CG1077	NA	NA
FBgn0037429	Osi19	Osiris 19	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0037435	CG18048	NA	NA
FBgn0037439	CG10286	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0037440	CRAT	Carnitine O-Acetyl-Transferase	NA
FBgn0037442	gzl	godzilla E3 ubiquitin protein ligase	godzilla E3 ubiquitin protein ligase (gzl) encodes a protein that ubiquitylates the SNARE protein encoded by Syb. It also promotes apico-basal transcytosis of the product of wg in the wing imaginal disc. [Date last reviewed: 2019-03-21]
FBgn0037443	Dmtn	Dementin	Dementin (Dmtn) encodes a protein that possesses an evolutionarily conserved interaction with members of the Amyloid β A4 protein family. Co-expression of Dmtn rescues the effect of over-expressing human Amyloid β A4 protein on development and behavior, and mutation of Dmtn causes aberrant processing of the product of Appl. [Date last reviewed: 2019-03-07]
FBgn0037445	CG9727	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0037446	Zif	Zinc-finger protein	Zinc-finger protein (Zif) encodes a C2H2-type zinc-finger transcription factor that is required for cell polarity and neuroblast self-renewal by regulating the expression and asymmetric localization of the product of aPKC. The phosphorylated product of Zif by aPKC is excluded from the nucleus, thus being the inactive form. [Date last reviewed: 2019-03-21]
FBgn0037465	CG1105	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0037466	CG1965	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0037467	Ufl1	UFM1 specific ligase 1	NA
FBgn0037468	CG1943	NA	NA
FBgn0037469	Dpck	Dephospho-CoA kinase	NA
FBgn0037470	Tailor	Tailor	Tailor (Tailor) encodes a cytoplasmic RNA-specific terminal uridylyltransferase. It acts as part of the terminal RNA uridylation-mediated processing (TRUMP) complex, marking RNA species for 3'-to-5' exoribonucleolytic decay by the product of Dis3l2. The product of Tailor regulates microRNA biogenesis by targeting precursor-microRNAs (predominantly mirtron hairpins) and targets unprocessed RNA polymerase III transcripts for degradation in a cytoplasmic RNA surveillance pathway. [Date last reviewed: 2019-03-14]
FBgn0037472	CG10098	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0037473	CG10068	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0037478	CG2656	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0037481	MAGE	MAGE	MAGE (MAGE) encodes a component of the SMC5/6 protein complex. This complex is critical to genome stability, and is required for homologous DNA recombination-based processes. [Date last reviewed: 2018-11-15]
FBgn0037482	CG10055	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0037489	CG1234	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0037490	CG10053	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0037491	CG1227	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0037492	Dtwd2	DTW domain containing 2	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0037504	CG1142	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0037513	pyd3	pyd3	pyd3 (pyd3) encodes a beta-alanine synthase involved in pyrimidine catabolism, beta-alanine biosynthesis and cuticle pigmentation. [Date last reviewed: 2019-03-14]
FBgn0037515	Sp7	Serine protease 7	Serine protease 7 (Sp7) encodes a hemolymphatic serine protease involved in the activation of the melanization cascade. [Date last reviewed: 2019-03-14]
FBgn0037518	CG2641	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-10-13]
FBgn0037526	ArgRS-m	Arginyl-tRNA synthetase, mitochondrial	NA
FBgn0037529	mRpS9	mitochondrial ribosomal protein S9	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0037530	EMC1	ER membrane protein complex subunit 1	ER Membrane protein Complex 1 (EMC1) encodes a subunit of the ER membrane protein complex (EMC). In fly retinas, EMC has been shown to be essential for the biosynthesis of multi-pass membrane proteins, but not for single-pass membrane proteins and secretory proteins. [Date last reviewed: 2019-03-07]
FBgn0037531	CG10445	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0037533	CD98hc	CD98 heavy chain	CD98 heavy chain (CD98hc) encodes a transporter involved in the transmembrane import of L-leucine. [Date last reviewed: 2019-09-12]
FBgn0037535	PIG-H	Phosphatidylinositol glycan anchor biosynthesis class H	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0037536	CG2698	NA	NA
FBgn0037537	CG2767	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0037538	CG3223	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0037539	CG10435	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0037540	Pbp95	PSEA-binding protein 95kD	PSEA-binding protein 95kD (Pbp95) encodes a protein that functions as one of three subunits of the small nuclear RNA (snRNA) activating protein complex, which binds as a complex to a proximal sequence element A (PSEA) to activate transcription of snRNA genes. [Date last reviewed: 2019-03-14]
FBgn0037541	CG2747	NA	NA
FBgn0037543	CG10903	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0037544	CG11035	NA	NA
FBgn0037548	CG7900	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0037549	CG7878	NA	NA
FBgn0037550	CG9667	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0037551	Arl8	ADP ribosylation factor-like 8	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0037552	CG7800	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0037553	CG18249	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0037554	PolI	DNA polymerase iota	DNA polymerase iota (PolI) encodes a protein involved in translesion synthesis. [Date last reviewed: 2019-09-26]
FBgn0037555	Ada2b	transcriptional Adaptor 2b	NA
FBgn0037556	CG9636	NA	NA
FBgn0037560	CR18228	NA	NA
FBgn0037561	CG9630	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0037566	mRpL1	mitochondrial ribosomal protein L1	NA
FBgn0037569	tex	tex	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0037573	CG7483	NA	NA
FBgn0037574	Coq2	Coenzyme Q biosynthesis protein 2	Coenzyme Q biosynthesis protein 2 (Coq2) encodes a prenyltransferase that catalyzes the prenylation of p-hydroxybenzoate with the isoprenoid chain in the process of CoQ production. It plays roles in development, CoQ and ATP biosynthesis, and lifespan regulation. [Date last reviewed: 2018-11-15]
FBgn0037578	PNKP	Polynucleotide kinase 3'-phosphatase	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0037580	DppIII	Dipeptidyl aminopeptidase III	NA
FBgn0037581	CG7352	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0037583	CG9684	NA	CG9684 encodes a protein belonging to the TDRD1 family that is predicted to have a role in the piRNA pathway. [Date last reviewed: 2019-03-07]
FBgn0037592	CG11737	NA	NA
FBgn0037602	SLIRP2	SRA stem-loop interacting RNA binding protein 2	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0037603	Sys1	Sys1 golgi trafficking protein	NA
FBgn0037606	CG8032	NA	NA
FBgn0037607	CG8036	NA	NA
FBgn0037608	mRpL19	mitochondrial ribosomal protein L19	NA
FBgn0037609	CG9773	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0037610	CG8043	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0037611	CG11755	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0037612	CG8112	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0037613	Cks85A	Cyclin-dependent kinase subunit 85A	Cyclin-dependent kinase subunit 85A (Cks85A) encodes a small protein that interacts with the products of Cdk1 and Cdk2. It also functions with the product of Skp2 to target specific substrates for destruction, including the product of dap. It is required for larval growth and to maintain diploidy in imaginal tissues. [Date last reviewed: 2019-03-07]
FBgn0037614	TMEM216	Transmembrane protein 216	NA
FBgn0037617	nom	numerous disordered muscles	NA
FBgn0037619	CG8159	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0037621	M1BP	Motif 1 Binding Protein	Motif 1 Binding Protein (M1BP) encodes a transcription pausing factor. It regulates gene transcription via interaction with the Hox proteins encoded by abd-A and Ubx. It contributes to the development of ovarian follicle cells. [Date last reviewed: 2019-06-13]
FBgn0037622	CG8202	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0037624	CG8223	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0037632	CCT7	Chaperonin containing TCP1 subunit 7	NA
FBgn0037633	CG9839	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0037634	hng2	hinge2	NA
FBgn0037635	CG9837	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0037637	IscU	Iron-sulfur cluster assembly enzyme	Iron-sulfur cluster assembly enzyme (IscU) encodes a ferrous iron binding protein involved in iron-sulfur cluster assembly. [Date last reviewed: 2019-09-12]
FBgn0037638	CG8379	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0037643	ScsbetaA	Succinyl-coenzyme A synthetase beta subunit, ADP-forming	Succinyl-coenzyme A synthetase β subunit, ADP-forming (ScsβA) encodes a subunit of the ligase that converts succinate to succinyl-CoA in the TCA/Krebs cycle. It contributes to apoptosis and sperm individualization. [Date last reviewed: 2019-09-12]
FBgn0037644	CG11964	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0037646	CAHbeta	Carbonic anhydrase beta	Carbonic anhydrase β (CAHβ) encodes a beta-class carbonate dehydratase that catalyzes the reversible hydration/dehydration of carbon dioxide to bicarbonate and protons. [Date last reviewed: 2019-09-12]
FBgn0037647	RagA-B	Ras-related GTP binding A/B	Ras-related GTP binding A/B (RagA-B) encodes a Ras family GTPase that forms a heterodimer with the product of RagC-D. The heterodimer localizes on the lysosome surface and functions to relay amino acid signals to activate the product of Tor by recruiting it to the lysosome. [Date last reviewed: 2019-03-14]
FBgn0037648	CG11975	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0037652	CG11980	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0037653	Iru	Iruka	NA
FBgn0037655	Kcmf1	Potassium channel modulatory factor 1	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0037656	CG11986	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0037657	hyx	hyrax	hyrax (hyx) encodes a protein recruited by signaling pathway specific transcriptional regulators such as the products of arm and ci and is important for the output of Wingless and Hedgehog pathways. [Date last reviewed: 2019-03-07]
FBgn0037659	Kdm2	Lysine demethylase 2	NA
FBgn0037660	beag	beag	beag (beag) encodes a spliceosomal protein required for normal neuromuscular junction development and function. It functions together with the product of Smu1 and can regulate the alternative mRNA splicing of Fas2. [Date last reviewed: 2018-11-15]
FBgn0037661	Ada	Adenosine deaminase	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0037667	CG16734	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-10-13]
FBgn0037669	Ibf2	Insulator binding factor 2	NA
FBgn0037670	Ibf1	Insulator binding factor 1	NA
FBgn0037671	ATP6AP2	ATPase H+ transporting accessory protein 2	NA
FBgn0037672	sage	salivary gland-expressed bHLH	salivary gland-expressed bHLH (sage) is only expressed in embryonic salivary glands. The product of sage works with the product of fkh to activate expression of salivary gland specific gene products (secreted proteins and enzymes that modify the secreted proteins). [Date last reviewed: 2019-03-14]
FBgn0037679	Aduk	Another Drosophila Unc-51-like kinase	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0037680	pasi2	pasiflora 2	pasiflora 2 (pasi2) encodes a septate junction protein involved in endothelial barrier function. [Date last reviewed: 2019-08-01]
FBgn0037683	CG18473	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0037686	RpL34b	Ribosomal protein L34b	Ribosomal protein L34b (RpL34b) encodes a ribosomal structural constituent. [Date last reviewed: 2019-07-11]
FBgn0037687	CG8132	NA	NA
FBgn0037688	CG9356	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0037696	GstZ1	Glutathione S transferase Z1	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0037700	CG8149	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0037702	CG8176	NA	NA
FBgn0037703	Kdm3	Lysine demethylase 3	Lysine demethylase 3 (Kdm3) encodes an enzyme that catalyzes the removal of methyl groups from the lysine 9 of the product of His3, and thereby promotes an open chromatin structure. [Date last reviewed: 2019-03-07]
FBgn0037705	mura	murashka	NA
FBgn0037707	RnpS1	RNA-binding protein S1	RNA-binding protein S1 (RnpS1) encodes a protein involved in RNA splicing and regulation of DNA transposition. [Date last reviewed: 2019-09-19]
FBgn0037708	CG9386	NA	NA
FBgn0037709	CG8199	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0037710	CG9393	NA	NA
FBgn0037712	CG16789	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0037713	CG16790	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0037714	CG9396	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0037715	CG9399	NA	NA
FBgn0037716	Son	Son RNA binding protein	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0037717	CG8301	NA	NA
FBgn0037718	P58IPK	P58IPK	NA
FBgn0037719	bocks	bocksbeutel	NA
FBgn0037720	CG8312	NA	NA
FBgn0037722	CG8319	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0037723	SpdS	Spermidine Synthase	NA
FBgn0037728	p23	p23	NA
FBgn0037734	trbd	trabid	trabid (trbd) encodes a OTU family member that interacts with the product of Apc when ubiquitinated. It affects the activity of the product of Apc in transcription. [Date last reviewed: 2019-03-14]
FBgn0037737	Pnn	Pinin	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0037739	CG12948	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0037741	Tti1	Telo2 interacting protein 1	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0037742	Rpt3R	Regulatory particle triple-A ATPase 3-related	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0037743	Alg12	Alg12 alpha-1,6-mannosyltransferase	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0037746	CG8478	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0037747	Naa80	N(alpha)-acetyltransferase 80	NA
FBgn0037749	CG9471	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0037750	Whamy	WHAMM and JMY related	WHAMM and JMY related (Whamy) encodes a Rac GTPase binding protein that promotes fast actin filament elongation. It is involved in cell migration, microtubule bundle formation and myoblast fusion. [Date last reviewed: 2019-09-26]
FBgn0037751	topi	matotopetli	NA
FBgn0037754	CG8500	NA	NA
FBgn0037755	CG12945	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0037756	CG8507	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0037757	CG8516	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0037758	CG9467	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0037759	CG8526	NA	NA
FBgn0037760	FBXO11	F-box protein 11	F-box protein 11 (FBXO11) encodes a subunit of a SCF-like E3 ubiquitin ligase involved in gene silencing mediated by both siRNAs and miRNAs.s [Date last reviewed: 2019-03-07]
FBgn0037770	Art4	Arginine methyltransferase 4	NA
FBgn0037773	CG5359	NA	NA
FBgn0037777	CG11722	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0037778	mtTFB2	mitochondrial transcription factor B2	NA
FBgn0037779	CG12811	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0037780	ohgt	ohgata	ohgata (ohgt) encodes a protein that controls growth by negatively regulating insulin signaling. It also has a role in maintaining presynaptic function in third-instar neuromuscular junction synapses. [Date last reviewed: 2018-11-15]
FBgn0037781	Fancl	Fancl	Fancl (Fancl) encodes a member of the Fanconi anemia pathway, which is a key mediator of DNA damage repair through homologous recombination. When mono-ubiquinated by the Fanconi core complex, it associates with the product of Fancd2 and localizes to sites of DNA damage. [Date last reviewed: 2018-11-15]
FBgn0037788	CAH7	Carbonic anhydrase 7	NA
FBgn0037792	TAF1B	TATA box-binding protein-associated factor RNA polymerase I subunit B	TATA box-binding protein-associated factor RNA polymerase I subunit B (TAF1B) encodes a protein that associates with the products of TAF1C-like and udd. It helps to regulate pre-rRNA transcription. [Date last reviewed: 2019-03-14]
FBgn0037794	CG6254	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0037802	Sirt6	Sirtuin 6	Sirtuin 6 (Sirt6) encodes an NAD-dependent histone deacetylase in the class IV of the Sirtuin family. It is involved in chromatin silencing and determination of adult lifespan. [Date last reviewed: 2019-03-14]
FBgn0037807	CG6293	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0037809	CG12818	NA	NA
FBgn0037810	sle	slender lobes	slender lobes (sle) encodes a component of the nucleolus. sle depletion alters the aggregation of nucleolar components and results in retardation of proliferation of Kenyon cells. [Date last reviewed: 2019-03-14]
FBgn0037814	CG6325	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0037815	Rrp46	Rrp46	Rrp46 (Rrp46) encodes a protein involved in gene expression regulation. [Date last reviewed: 2019-07-11]
FBgn0037822	CG14683	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0037831	Cap-H2	Chromosome associated protein H2	Chromosome associated protein H2 (Cap-H2) encodes a condensin protein involved in chromatin organization and chromosome segregation. [Date last reviewed: 2019-07-11]
FBgn0037834	Art1	Arginine methyltransferase 1	NA
FBgn0037837	CG14693	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0037838	TTLL15	Tubulin tyrosine ligase-like 15	NA
FBgn0037842	CG6567	NA	NA
FBgn0037843	CG4511	NA	NA
FBgn0037844	CG4570	NA	NA
FBgn0037846	CG6574	NA	NA
FBgn0037848	Tsp86D	Tetraspanin 86D	Tetraspanin 86D (Tsp86D) encodes a member of the tetraspanin superfamily. With two other tetraspanins, encoded by Tsp3A and Tsp26A, it regulates the trafficking of the product of kuz and consequently Notch signaling and several Notch-dependent developmental processes. [Date last reviewed: 2019-03-14]
FBgn0037850	CG14695	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0037852	Tpc1	Thiamine pyrophosphate carrier protein 1	Thiamine pyrophosphate carrier protein 1 (Tpc1) encodes an important protein for mitochondrial metabolism located at the inner mitochondrial membrane. Its main role is to import thiamine pyrophosphate (ThPP) into mitochondria. ThPP is an essential coenzyme for the E1 components of pyruvate dehydrogenase and oxoglutarate dehydrogenase, which are located in the mitochondrial matrix. [Date last reviewed: 2019-03-14]
FBgn0037853	CG14696	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0037855	CG6621	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0037856	Leash	Leash	Leash (Leash) encodes a member of the arrestin domain-containing protein family, which functions as an adaptor molecule for protein degradation. It inhibits growth by inducing degradation of the product of yki via the lysosomal pathway. [Date last reviewed: 2019-03-14]
FBgn0037873	SdhC	Succinate dehydrogenase, subunit C	Succinate dehydrogenase, subunit C (SdhC) encodes a protein involved in mitochondrial electron transport and oxidative stress response. [Date last reviewed: 2019-09-19]
FBgn0037874	Tctp	Translationally controlled tumor protein	Translationally controlled tumor protein (Tctp) encodes a protein that belongs to the TCTP family. It interacts with the GTPase encoded by Rheb to regulate organ growth. It is required for DNA damage response and genome stability. [Date last reviewed: 2019-03-14]
FBgn0037875	ZnT86D	Zinc transporter 86D	Zinc transporter 86D (ZnT86D) encodes a transporter involved in zinc detoxification. [Date last reviewed: 2019-09-12]
FBgn0037876	CG4820	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0037877	CG6689	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0037878	CG6693	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0037880	CG17726	NA	NA
FBgn0037881	GCC88	GRIP and coiled-coil domain containing 88 kDa	GRIP and coiled-coil domain containing 88 kDa (GCC88) encodes a member of the Golgin family. It associates with Arl1, an Arf-like GTPase and Rab GTPases. It localizes to the trans-Golgi where it may be involved in vesicle-mediated transport or maintaining Golgi architecture. [Date last reviewed: 2021-01-28]
FBgn0037882	CG17187	NA	NA
FBgn0037883	Dph3	Diphthamide biosynthesis 3	NA
FBgn0037884	Arfip	Arfaptin	Arfaptin (Arfip) a protein that functions to tether the dynactin complex to the Golgi membrane in motor neurons. This function is required for normal synaptic growth during larval development. [Date last reviewed: 2019-03-07]
FBgn0037885	CG17721	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0037890	CG17734	NA	NA
FBgn0037891	CG5214	NA	NA
FBgn0037892	mRpL40	mitochondrial ribosomal protein L40	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0037894	Ranbp9	Ranbp9	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0037896	ninaG	ninaG	ninaG (ninaG) encodes a glucose-methanol-choline oxidoreductase required for the biogenesis of the rhodopsin chromophore (3S)-3-hydroxyretinal, likely by stimulating conversion between the two enantiomers of 3-hydroxyretinal. [Date last reviewed: 2019-03-14]
FBgn0037897	CG5270	NA	NA
FBgn0037899	RpL24-like	Ribosomal protein L24-like	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0037900	CG5276	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0037901	Exd2	Exonuclease 3'-5' domain-containing 2	NA
FBgn0037902	CG5281	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0037906	PGRP-LB	Peptidoglycan recognition protein LB	Peptidoglycan recognition protein LB (PGRP-LB) encodes a secreted protein with an amidase activity that scavenges DAP-type peptidoglycan, a cell wall component found on Gram-negative bacteria and certain Gram positive bacteria. It negatively regulates the immune deficiency pathway. [Date last reviewed: 2019-03-14]
FBgn0037911	CG10898	NA	NA
FBgn0037913	fabp	fatty acid binding protein	fatty acid binding protein (fabp) encodes a protein involved in long term memory. [Date last reviewed: 2019-03-07]
FBgn0037915	CG6790	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0037916	CG5342	NA	NA
FBgn0037917	wkd	whacked	whacked (wkd) encodes a RabGAP that catalyzes the GTPase activity of its Rab-GTP partners. Its essential substrate appears to be the product of Rab35. wkd mutations are associated with seamless tube defects in the tracheal system. [Date last reviewed: 2019-03-21]
FBgn0037918	CG6791	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0037920	CG14710	NA	NA
FBgn0037923	CG6813	NA	NA
FBgn0037924	CG14712	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0037926	Elp1	Elongator complex protein 1	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0037930	CG14715	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0037931	CG18476	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0037933	Ho	Heme oxygenase	Heme oxygenase (Ho) encodes a heme oxygenase involved in heme metabolism. [Date last reviewed: 2019-09-12]
FBgn0037934	CG6830	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0037942	CG14721	NA	NA
FBgn0037943	CG14722	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0037944	CG6923	NA	NA
FBgn0037949	prd1	pruning defect 1	NA
FBgn0037955	Kyat	Kynurenine aminotransferase	NA
FBgn0037958	CG6962	NA	NA
FBgn0037960	mthl5	methuselah-like 5	methuselah-like 5 (mthl5) encodes a G protein-coupled receptor involved in heart morphogenesis. [Date last reviewed: 2019-07-11]
FBgn0037963	Cad87A	Cadherin 87A	NA
FBgn0037973	CG18547	NA	NA
FBgn0037974	CG12224	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0037975	CG3397	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0037978	KLHL18	Kelch like family member 18	NA
FBgn0037979	GCC185	GRIP and coiled-coil domain containing 185 kDa	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0037980	DCAF12	DDB1 and CUL4 associated factor 12	NA
FBgn0037981	Spt3	Spt3	Spt3 (Spt3) encodes a encodes a subunit of the SAGA chromatin modifying complex. [Date last reviewed: 2019-08-01]
FBgn0037989	ATP8B	ATPase 8B	ATPase 8B (ATP8B) encodes a phospholipid flippase involved in olfaction. [Date last reviewed: 2019-09-12]
FBgn0037998	Cog1	Component of oligomeric golgi complex 1	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0037999	CG4860	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0038013	CG10038	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0038016	MBD-R2	MBD-R2	MBD-R2 (MBD-R2) encodes a Zinc finger C2H2 transcription factor. It is a component of nonspecific lethal (NSL) complex involved in transcriptional activation. [Date last reviewed: 2019-09-12]
FBgn0038020	GstD9	Glutathione S transferase D9	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0038034	Cyp9f3	Cytochrome P450 9f3	NA
FBgn0038037	Cyp9f2	Cytochrome P450 9f2	NA
FBgn0038038	Sccpdh2	Saccheropin dehydrogenase 2	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0038039	CG5196	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0038043	CG17202	NA	NA
FBgn0038046	CG5641	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0038047	CG5245	NA	NA
FBgn0038049	Srlp	Spliceosome-ribosome linker protein	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0038053	CG18549	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0038055	trus	toys are us	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0038056	CG5961	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0038057	Polr3C	RNA polymerase III subunit C	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0038058	CG5608	NA	NA
FBgn0038065	Snx3	Sorting nexin 3	Sorting nexin 3 (Snx3) encodes a protein involved in the secretion of the morphogen encoded by wg. It regulates the retromer-dependent recycling of the transmembrane cargo encoded by wls. [Date last reviewed: 2019-08-01]
FBgn0038080	CG12279	NA	NA
FBgn0038088	CG10126	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0038098	CG7381	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-10-13]
FBgn0038099	CG7091	NA	NA
FBgn0038100	Paip2	polyA-binding protein interacting protein 2	NA
FBgn0038102	CG14383	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-10-13]
FBgn0038105	yellow-f2	yellow-f2	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0038106	CG7488	NA	NA
FBgn0038107	CG17327	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0038108	CG7518	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0038109	CG11656	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-10-13]
FBgn0038110	CG8031	NA	NA
FBgn0038118	timeout	timeout	timeout (timeout) encodes a role in the maintenance of chromosome integrity and in the light synchronization of the adult circadian clock [Date last reviewed: 2019-03-14]
FBgn0038128	Ravus	Ravus	NA
FBgn0038129	TBC1D5	TBC1 domain family member 5	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0038145	Droj2	DnaJ-like-2	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0038146	CG9799	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0038149	GILT1	Gamma-interferon-inducible lysosomal thiol reductase 1	NA
FBgn0038156	side-IV	sidestep IV	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0038166	CG9588	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0038167	Lkb1	Lkb1 kinase	Lkb1 kinase (Lkb1) encodes a serine/threonine kinase that plays a master role for activating the AMP-dependent protein kinase (AMPK) family kinases. It is a well-characterized tumor suppressor and regulates processes like cell polarity, metabolism, apoptosis, and cell growth. [Date last reviewed: 2019-03-14]
FBgn0038168	omd	oocyte maintenance defects	NA
FBgn0038183	CG9286	NA	NA
FBgn0038194	Cyp6d5	Cytochrome P450 6d5	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0038195	CG3061	NA	NA
FBgn0038196	CG9922	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0038197	foxo	forkhead box, sub-group O	NA
FBgn0038198	Npc2b	Niemann-Pick type C-2b	NA
FBgn0038206	twf	twinfilin	twinfilin (twf) encodes a ubiquitously expressed actin monomer binding protein that is structurally related to the product of tsr and inhibits actin filament assembly. It is highly conserved and is present in all eukaryotes except plants. Its roles include bristle and neuronal development. [Date last reviewed: 2019-03-14]
FBgn0038223	Afti	Aftiphilin	Aftiphilin (Afti) encodes an AP-1 adaptor complex binding protein involved in eye photoreceptor development and intracellular transport. [Date last reviewed: 2019-09-12]
FBgn0038224	ATPsynE	ATP synthase, subunit E	NA
FBgn0038233	HtrA2	HTRA2-related serine protease	NA
FBgn0038234	mRpL11	mitochondrial ribosomal protein L11	NA
FBgn0038235	CG8461	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0038237	Pde6	Phosphodiesterase 6	NA
FBgn0038243	CG8066	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0038244	CG7987	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0038250	CG3505	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0038251	Hexim	Hexamethylene bisacetamide inducible	Hexamethylene bisacetamide inducible (Hexim) encodes an RNA binding protein. When associated with snRNA:7SK, it recruits and inhibits the positive transcription elongation factor encoded by Cdk9. Regulated release and re-sequestration of the product of Cdk9 by the snRNA:7SK snRNP plays an essential role in RNA polymerase II elongation control. [Date last reviewed: 2019-03-07]
FBgn0038256	CG7530	NA	NA
FBgn0038260	CG14855	NA	NA
FBgn0038268	CG3631	NA	NA
FBgn0038269	Rrp6	Rrp6	Rrp6 (Rrp6) encodes an exoribonuclease that forms part of the RNA processing exosome complex. It is involved in the regulation of cell cycle progresion and mRNA surveillance. [Date last reviewed: 2019-09-12]
FBgn0038271	UQCR-C1	Ubiquinol-cytochrome c reductase core protein 1	NA
FBgn0038272	Dph2	Diphthamide biosynthesis 2	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0038274	Nup93-2	Nucleoporin 93kD-2	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0038275	CG3817	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0038286	CG6966	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0038290	CG6912	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0038291	CG3984	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0038296	CG6752	NA	NA
FBgn0038300	Mau2	Mau2 sister chromatid cohesion factor	Mau2 sister chromatid cohesion factor (Mau2) encodes a protein that interacts with the product of Nipped-B to form the kollerin complex, which loads the cohesin complex onto chromosomes. The product of Mau2 and cohesin participate in transcriptional regulation and DNA repair. [Date last reviewed: 2019-03-14]
FBgn0038301	CG6654	NA	NA
FBgn0038302	CG4210	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0038303	SIDL	Shal Interactor of Di-Leucine Motif	NA
FBgn0038304	CG12241	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0038306	Art3	Arginine methyltransferase 3	NA
FBgn0038307	mRpS10	mitochondrial ribosomal protein S10	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0038309	Amt	Ammonium transporter	Ammonium transporter (Amt) encodes a protein required for ammonia detection. [Date last reviewed: 2019-03-07]
FBgn0038311	CG14864	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0038312	Zip88E	Zinc/iron regulated transporter-related protein 88E	NA
FBgn0038313	CG4338	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0038316	CG6276	NA	NA
FBgn0038318	CG6236	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0038319	mRpL9	mitochondrial ribosomal protein L9	NA
FBgn0038320	Cyfip	Cytoplasmic FMR1 interacting protein	Cytoplasmic FMR1 interacting protein (Cyfip) encodes an essential protein that is a component of the WAVE actin nucleator complex. It controls actin cytoskeleton remodeling and interacts with the products of Fmr1 and Rac1. It controls morphogenesis and synapse organization. [Date last reviewed: 2020-07-09]
FBgn0038321	CG6218	NA	NA
FBgn0038324	CG5038	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0038325	Atg4b	Autophagy-related 4b	Autophagy-related 4b (Atg4b) encodes a cysteine protease that cleaves the precursor product of Atg8a at the C-terminal region, thereby initiating autophagosome formation. [Date last reviewed: 2018-11-15]
FBgn0038326	CG5044	NA	NA
FBgn0038327	Trax	Translin associated factor X	Translin associated factor X (Trax) encodes a protein that, together with the product of trsn, forms the trsn/Trax complex, a ribonuclease that facilitates RNA-induced silencing complex (RISC) activation and has been implicated in many different processes, including starvation-induced sleep suppression. [Date last reviewed: 2019-03-14]
FBgn0038330	CG14868	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0038331	Ccm3	Cerebral cavernous malformation 3	Cerebral cavernous malformation 3 (Ccm3) encodes a small scaffolding protein that forms dimers with the product of GckIII. In the tracheal system, it is required specifically in terminal cells, and its loss is associated with tube dilation. [Date last reviewed: 2019-03-07]
FBgn0038332	CG6136	NA	NA
FBgn0038344	obe	obelus	obelus (obe) encodes a Ski2-family helicase that regulates alternative mRNA splicing of crb. It is required for cell polarity and adherens junction organization. [Date last reviewed: 2019-09-26]
FBgn0038348	AOX2	Aldehyde oxidase 2	Aldehyde oxidase 2 (AOX2) encodes a pyridoxal oxidase involved in pyridoxal metabolism. [Date last reviewed: 2019-09-19]
FBgn0038349	AOX3	Aldehyde oxidase 3	Aldehyde oxidase 3 (AOX3) encodes a pyridoxal oxidase involved in pyridoxal metabolism. [Date last reviewed: 2019-09-19]
FBgn0038353	CG5399	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0038360	CG9590	NA	NA
FBgn0038363	Acyp2	Acylphosphatase 2	Acylphosphatase 2 (Acyp2) encodes a small cytosolic enzyme that catalyses the hydrolysis of carboxyl phosphate bonds. Its exact role and function are unknown. [Date last reviewed: 2019-03-07]
FBgn0038365	CG9593	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0038369	Arpc3A	Actin-related protein 2/3 complex, subunit 3A	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0038371	Pbp45	PSEA-binding protein 45kD	PSEA-binding protein 45kD (Pbp45) encodes a protein that functions as one of three subunits of the small nuclear RNA (snRNA) activating protein complex, which binds as a complex to a proximal sequence element A (PSEA) to activate transcription of snRNA genes. [Date last reviewed: 2019-03-14]
FBgn0038373	CG4546	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0038376	Hmt-1	Heavy metal tolerance factor 1	NA
FBgn0038381	EndoU	Endoribonuclease U-specific	Endoribonuclease U-specific (EndoU) encodes a endoribonuclease belonging to the eukaryotic endoU ribonuclease family. It is essential for viability and plays a crucial role in the nervous system, contributing to complex neuronal networks largely dependent on cholinergic neurons. [Date last reviewed: 2018-11-15]
FBgn0038387	blp	black pearl	"black pearl (blp) encodes a conserved mitochondrial inner membrane protein. Its loss decreases cytochrome c oxidase activity and causes ROS production, leading to melanotic lesions (""black pearls"") in blp-deficient flies. [Date last reviewed: 2019-03-07]"
FBgn0038388	CG4287	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0038389	CG5516	NA	NA
FBgn0038390	Rbf2	Retinoblastoma-family protein 2	NA
FBgn0038391	GATAe	GATAe	GATAe (GATAe) encodes a endoderm-specific GATA factor. It regulates endoderm differentiation and intestinal stem cell maintenance. [Date last reviewed: 2019-09-12]
FBgn0038395	CG10407	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0038396	CG5013	NA	NA
FBgn0038397	CG10185	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0038400	Mic26-27	MICOS subunit 26/27	NA
FBgn0038401	CG5916	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0038407	CG6126	NA	NA
FBgn0038414	CG6901	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0038415	CG17929	NA	NA
FBgn0038416	CG17930	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0038418	pad	poils au dos	NA
FBgn0038421	CG17931	NA	NA
FBgn0038424	Fntb	Farnesyl transferase beta subunit	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0038425	CG14881	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0038426	mRpS33	mitochondrial ribosomal protein S33	NA
FBgn0038427	ema	endosomal maturation defective	endosomal maturation defective (ema) encodes a protein involved in membrane trafficking that is required for endosomal maturation and autophagy. [Date last reviewed: 2018-11-15]
FBgn0038428	CG14894	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0038429	CG14882	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0038431	CG10405	NA	NA
FBgn0038432	CG14883	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0038435	Gyc89Da	Guanylyl cyclase at 89Da	Guanylyl cyclase at 89Da (Gyc89Da) encodes an atypical soluble guanylyl cyclase. It heterodimerizes with the product of Gyc88E to form an oxygen-sensitive soluble guanylyl cyclase, which likely functions as a neuronal oxygen detector, activated at reduced oxygen levels. [Date last reviewed: 2019-03-07]
FBgn0038436	Gyc89Db	Guanylyl cyclase at 89Db	Guanylyl cyclase at 89Db (Gyc89Db) encodes an atypical soluble guanylyl cyclase. It heterodimerizes with the product of Gyc88E to form an oxygen-sensitive soluble guanylyl cyclase, which likely functions as a neuronal oxygen detector, activated at reduced oxygen levels. [Date last reviewed: 2019-03-07]
FBgn0038437	Sdhaf3	Succinate dehydrogenase assembly factor 3	Succinate dehydrogenase assembly factor 3 (Sdhaf3) encodes a protein chaperone that functions within the mitochondrial matrix and mediates the biogenesis of the product of SdhB. [Date last reviewed: 2019-03-14]
FBgn0038438	Der-2	Derlin-2	NA
FBgn0038446	CG14903	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0038453	Arl6IP1	ADP-ribosylation factor-like 6 interacting protein 1	NA
FBgn0038454	CG10324	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0038461	EMC2B	ER membrane protein complex subunit 2B	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0038462	EMC2A	ER membrane protein complex subunit 2A	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0038463	CG3534	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0038465	Irc	Immune-regulated catalase	Immune-regulated catalase (Irc) encodes a catalase involved in oxidant detoxification. [Date last reviewed: 2019-09-12]
FBgn0038467	AdSL	Adenylosuccinate Lyase	Adenylosuccinate Lyase (AdSL) encodes a protein that might be a lyase involved in purine nucleotide metabolic process based on orthology. [Date last reviewed: 2019-03-07]
FBgn0038470	CG18213	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0038471	Trm7-32	tRNA methyltransferase 7-32	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0038472	CG3995	NA	NA
FBgn0038473	Ns1	Nucleostemin 1	Nucleostemin 1 (Ns1) encodes a GTPase that is enriched in the peripheral granular components of nucleoli of most larval and adult cells. It is required for nucleolar release of the large ribosomal subunit. Depletion of the Ns1 product reduces viability of midgut imaginal island cells and ribosome abundance in polyploid cells. [Date last reviewed: 2018-11-15]
FBgn0038474	mRpS11	mitochondrial ribosomal protein S11	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0038475	Keap1	Keap1	Keap1 (Keap1) encodes a protein that interacts with the product of cnc to regulate the activation of genes by oxidative stress. [Date last reviewed: 2019-03-14]
FBgn0038476	kuk	kugelkern	kugelkern (kuk) encodes a nuclear envelope protein required for nuclear elongation during cellularization. It shares structural and functional similarities to lamins. [Date last reviewed: 2018-11-15]
FBgn0038478	cal1	chromosome alignment defect 1	chromosome alignment defect 1 (cal1) encodes a protein that is required for maintenance of the epigenetic marks specifying centromeres. It binds to newly synthesized centromere-specific histone H3 variant encoded by cid and recruits it to the centromere by binding to the centromere protein encoded by Cenp-C. [Date last reviewed: 2019-03-07]
FBgn0038488	m-cup	mann-cup	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0038490	Smug	Single-strand-selective monofunctional uracil-DNA glycosylase	NA
FBgn0038491	CG5292	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0038499	Brf	Brf RNA polymerase III subunit	Brf (Brf) encodes a transcription factor binding protein involved in transcription mediated by RNA polymerase III. [Date last reviewed: 2019-09-19]
FBgn0038504	Sur-8	Sur-8	NA
FBgn0038515	CG5823	NA	NA
FBgn0038516	P5cr-2	Pyrroline-5-carboxylate reductase-like 2	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0038519	Prx3	Peroxiredoxin 3	Peroxiredoxin 3 (Prx3) encodes an antioxidant protein involved in hydrogen peroxide catabolism and regulation of apoptosis. [Date last reviewed: 2019-08-01]
FBgn0038524	sll	slalom	slalom (sll) encodes the first transporter of 3'-phosphoadenosine 5'-phosphosulfate (PAPS), that transfers PAPS from cytosol into the lumen of Golgi. It contributes to the sulfation of glycans and proteins, the regulation of several signaling pathways (Hh, Wingless) mediated by glycosaminoglycans during patterning and morphogenesis, and the determination of the embryonic dorsal/ventral axis. [Date last reviewed: 2019-03-14]
FBgn0038528	CG14326	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-10-13]
FBgn0038532	CG14322	NA	NA
FBgn0038533	CG7523	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0038535	alt	aluminum tubes	NA
FBgn0038536	CG7655	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0038545	pasi1	pasiflora 1	pasiflora 1 (pasi1) encodes a septate junction protein involved in endothelial barrier function. [Date last reviewed: 2019-08-01]
FBgn0038546	CG7379	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0038547	CG17803	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0038548	CG17806	NA	NA
FBgn0038549	Nnk	Nicknack	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0038551	Odj	Oddjob	NA
FBgn0038552	Alg1	ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase	NA
FBgn0038564	CG7785	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0038569	CG7218	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0038576	Arp5	Actin-related protein 5	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0038577	CG12321	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0038578	MED17	Mediator complex subunit 17	NA
FBgn0038582	CG7988	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0038583	CG7183	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0038584	mTerf5	mitochondrial transcription termination factor 5	mitochondrial transcription termination factor 5 (mTerf5) encodes a protein that regulates mitochondrial DNA transcription and replication by relieving the block exerted by the DNA binding factor encoded by mTTF. Both proteins cooperate in coordinating the passage of transcription and replication complexes that move on opposite DNA strands. [Date last reviewed: 2018-11-15]
FBgn0038585	Non3	Novel nucleolar protein 3	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0038586	CG7168	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0038588	CG7156	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0038590	CG12320	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0038593	Vps39	Vacuolar protein sorting 39	Vacuolar protein sorting 39 (Vps39) encodes a subunit of the homotypic fusion and vacuole protein sorting (HOPS) complex required for autophagosome maturation. [Date last reviewed: 2019-07-11]
FBgn0038595	CG7142	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0038597	CG8064	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0038601	Polr1E	RNA polymerase I subunit E	NA
FBgn0038608	WRNexo	WRN exonuclease	WRN exonuclease (WRNexo) encodes a 3'-5' exonuclease that cleaves 3' ends of both single-stranded and duplex DNA substrates that resemble DNA structures present during DNA replication. It may act in concert with RecQ family helicases to resolve Holliday junctions or other unusual DNA structures. It is likely to be involved in DNA replication, recombination and repair, and is essential for early embryonic development. [Date last reviewed: 2019-03-21]
FBgn0038609	Nup43	Nucleoporin 43kD	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0038612	cona	corona	corona (cona) encodes a component of the synaptonemal complex that is required for many meiotic processes, including homolog pairing, recombination, and chromosome segregation at meiosis I. [Date last reviewed: 2018-11-15]
FBgn0038617	Wdr37	WD repeat domain 37	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0038619	CG7685	NA	NA
FBgn0038638	CG7702	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0038640	CG7706	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0038649	PGS1	Phosphatidylglycerophosphate synthase 1	NA
FBgn0038651	Epg5	ectopic P-granules autophagy protein 5	NA
FBgn0038652	CG7720	NA	NA
FBgn0038659	EndoA	Endophilin A	Endophilin A (EndoA) encodes an essential protein for synaptic vesicle endocytosis. It recruits or stabilizes the product of Synj (required for vesicle uncoating) to endocytic membranes. [Date last reviewed: 2019-03-07]
FBgn0038660	Sgsh	N-sulfoglucosamine sulfohydrolase	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0038662	Mpc1	Mitochondrial pyruvate carrier	Mitochondrial pyruvate carrier (Mpc1) encodes an obligate subunit of the mitochondrial pyruvate carrier, which transports pyruvate across the mitochondrial inner membrane. [Date last reviewed: 2019-03-14]
FBgn0038666	Smu1	Smu1 spliceosomal factor	Smu1 spliceosomal factor (Smu1) encodes a spliceosomal protein required for normal neuromuscular junction development and function. It functions together with the product of beag. Both proteins can regulate synaptic levels of the product of Fas2. [Date last reviewed: 2018-11-15]
FBgn0038672	CG6005	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0038673	CG14286	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0038675	CG6013	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0038678	mRpL55	mitochondrial ribosomal protein L55	mitochondrial ribosomal protein L55 (mRpL55) encodes a protein involved in mitochondrial biogenesis and cell division. [Date last reviewed: 2019-03-14]
FBgn0038679	CG6040	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0038680	Cyp12a5	Cytochrome P450 12a5	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0038681	Cyp12a4	Cytochrome P450 12a4	NA
FBgn0038682	CG5835	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0038683	CG11779	NA	NA
FBgn0038686	CG5555	NA	NA
FBgn0038692	Polr2M	RNA polymerase II subunit M	NA
FBgn0038693	unc79	uncoordinated 79	uncoordinated 79 (unc79) encodes a protein involved in circadian locomotor rhythms. [Date last reviewed: 2019-09-19]
FBgn0038704	CG5316	NA	NA
FBgn0038705	CG11626	NA	NA
FBgn0038720	CG6231	NA	NA
FBgn0038721	subdued	subdued	subdued (subdued) encodes a chloride ion channel activated by calcium and heat belonging to the TMEM16 family. Its roles include host defense against ingested pathogenic bacteria and modulation of sensory neuronal signaling. [Date last reviewed: 2018-11-15]
FBgn0038722	Nup58	Nucleoporin 58kD	NA
FBgn0038723	CG6195	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0038735	MICU3	Mitochondrial calcium uptake 3	NA
FBgn0038737	CG11447	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0038738	CG4572	NA	NA
FBgn0038739	CG4686	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0038741	CG17186	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0038742	Arc42	Arc42	NA
FBgn0038744	CG4733	NA	"CG4733 encodes a protein that is predicted to be the B""/PR72 subunit of Protein Phosphatase 2A (PP2A) regulatory B unit. The B subunits determine the substrate specificity of the enzyme. [Date last reviewed: 2019-03-07]"
FBgn0038745	ClpX	Caseinolytic protease chaperone subunit	NA
FBgn0038746	Surf6	Surfeit 6	NA
FBgn0038747	RhoGAP92B	Rho GTPase activating protein at 92B	NA
FBgn0038755	Hs6st	Heparan sulfate 6-O-sulfotransferase	Heparan sulfate 6-O-sulfotransferase (Hs6st) encodes a heparan sulfate modifying enzyme, which transfers a sulfate group to the 6-O position of glucosamine residues of heparan sulfate. Loss of Hs6st eliminates 6-O sulfation, but increases 2-O sulfation performed by the product of Hs2st. Simultaneous elimination of Hs6st and Hs2st disrupts FGF, Wg and Dpp signaling pathways. [Date last reviewed: 2019-03-07]
FBgn0038760	MED25	Mediator complex subunit 25	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0038763	PIG-L	Phosphatidylinositol glycan anchor biosynthesis class L	NA
FBgn0038765	CG4424	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0038766	CG4854	NA	NA
FBgn0038767	trem	trade embargo	trade embargo (trem) encodes a chromatin-associated zinc-finger protein required to initiate programmed meiotic double-strand break formation. [Date last reviewed: 2018-11-08]
FBgn0038768	CG4936	NA	NA
FBgn0038769	Regnase-1	Regnase 1	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0038771	CG4390	NA	NA
FBgn0038772	mdlc	midlife crisis	midlife crisis (mdlc) encodes a nuclear protein that is required for maintaining neuronal differentiation. [Date last reviewed: 2019-03-14]
FBgn0038787	CG4360	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0038788	Sirt2	Sirtuin 2	Sirtuin 2 (Sirt2) encodes an NAD-dependent histone deacetylase in the class I of the Sirtuin family. It is involved in protein deacetylation, determination of adult lifespan, and neurodegeneration. [Date last reviewed: 2019-03-14]
FBgn0038803	CG5191	NA	NA
FBgn0038804	CG10877	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0038805	TFAM	mitochondrial transcription factor A	mitochondrial transcription factor A (TFAM) encodes a protein essential for mtDNA transcription and replication. It also binds to mtDNA nonspecifically, and plays a role in mtDNA maintenance by packaging mtDNA. [Date last reviewed: 2019-03-14]
FBgn0038806	CG5412	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0038808	Srp14	Signal recognition particle 14	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0038809	CG16953	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0038810	Srp72	Signal recognition particle 72	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0038811	Pus1	Pseudouridine synthase 1	NA
FBgn0038815	CG5466	NA	NA
FBgn0038816	Lrrk	Leucine-rich repeat kinase	Leucine-rich repeat kinase (Lrrk) encodes a large Ser/Thr kinase involved in mRNA translational control, cytoskeleton regulation, vesicle trafficking, autophagy, and immune response. [Date last reviewed: 2019-03-14]
FBgn0038826	Syp	Syncrip	Syncrip (Syp) encodes an RNA-binding protein that regulates the localization and translation of mRNAs involved in multiple processes. It is required for synapse morphology and synaptic transmission at the neuromuscular junction as well as being involved in oocyte axis specification and control of neuronal cell fates in the mushroom body. [Date last reviewed: 2018-11-08]
FBgn0038827	Fancd2	Fancd2	NA
FBgn0038829	CG17271	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0038830	CG17272	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0038832	CG15695	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0038834	RpS30	Ribosomal protein S30	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0038842	hdly	hadley	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0038853	RhoGAP93B	Rho GTPase activating protein at 93B	NA
FBgn0038854	CG7044	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0038855	CG5745	NA	NA
FBgn0038857	Bdbt	Bride of doubletime	Bride of doubletime (Bdbt) encodes a protein that binds to a nuclear localization signal in the product of dco and is necessary for normal circadian dco activity on the product of per. The product of Bdbt also accumulates in cytosolic foci in photoreceptors during the middle of the night. [Date last reviewed: 2019-03-07]
FBgn0038858	CG5793	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0038860	Ice2	Interacts with the C terminus of ELL 2	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0038861	Trm7-34	tRNA methyltransferase 7-34	NA
FBgn0038862	Usp8	Ubiquitin specific protease 8	Ubiquitin specific protease 8 (Usp8) encodes a protease involved in protein deubiquitination. It contributes to the integrity of ESCRT sorting machinery and the regulation of Hedgehog and Wingless signaling pathways. [Date last reviewed: 2019-03-21]
FBgn0038865	cDIP	Common Dpr-interacting protein	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0038868	CG5862	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0038869	Smyd5	SET and MYND domain containing, class 5	NA
FBgn0038870	Oga	O-GlcNAcase	O-GlcNAcase (Oga) encodes a protein that, together with the product of sxc, is responsible for O-GlcNAcylation. O-GlcNAcylation is a dynamic post-translational modification that modifies serine and threonine residues of proteins, and plays important roles in biological functions such as metabolism and neurodegeneration. [Date last reviewed: 2019-03-14]
FBgn0038871	CG3337	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0038872	Nelf-A	Negative elongation factor A	NA
FBgn0038874	ETHR	ETHR	ETHR (ETHR) encodes two distinct G protein-coupled receptors through alternative splicing. During development, the receptors are essential in initiating the molt-related behaviors of ecdysis, and in adults they function to promote juvenile hormone signaling and reproduction. [Date last reviewed: 2018-11-08]
FBgn0038876	Idi	Isopentenyl-diphosphate delta isomerase	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0038877	CG3308	NA	NA
FBgn0038881	CG16791	NA	NA
FBgn0038889	Fancm	Fanconi anemia group M helicase	Fanconi anemia group M helicase (Fancm) encodes a protein that promotes repair of DNA interstrand crosslinks through the Fanconi anemia pathway and non-crossover repair of DNA double-strand breaks. [Date last reviewed: 2019-03-07]
FBgn0038890	sp3	spermathreecae	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0038893	Archease	Archease	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0038903	Polr1H	RNA polymerase I subunit H	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0038909	CG6569	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-10-13]
FBgn0038912	CG6656	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0038917	CG6678	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0038922	Idh3b	Isocitrate dehydrogenase 3b	Isocitrate dehydrogenase 3b (Idh3b) encodes a mitochondrial enzyme of the tricarboxylic acid cycle involved in salivary gland cell autophagy. [Date last reviewed: 2019-09-12]
FBgn0038923	mRpL35	mitochondrial ribosomal protein L35	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0038924	CG6028	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0038925	Cchl	Cytochrome c heme lyase	NA
FBgn0038927	CG6015	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0038928	Fadd	Fas-associated death domain	Fas-associated death domain (Fadd) encodes an adaptor protein that functions downstream of the product of imd and upstream of the caspase encoded by Dredd in the immune deficiency pathway. [Date last reviewed: 2019-03-07]
FBgn0038947	Sar1	Secretion-associated Ras-related 1	Secretion-associated Ras-related 1 (Sar1) encodes a small GTPase that is recruited to the endoplasmic reticulum and initiates the recruitment of the COPII subunit complex Sec23/Sec24. [Date last reviewed: 2018-11-08]
FBgn0038948	JMJD6	Jumonji domain containing 6	NA
FBgn0038950	CG5382	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0038951	Polr3F	RNA polymerase III subunit F	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0038952	CG7069	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0038953	CG18596	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0038957	CG7059	NA	NA
FBgn0038961	CG13850	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0038964	Nop56	Nop56	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0038965	mats	mob as tumor suppressor	NA
FBgn0038966	pinta	prolonged depolarization afterpotential (PDA) is not apparent	NA
FBgn0038968	CG12499	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0038972	CG7054	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0038974	CG5377	NA	NA
FBgn0038976	Pfdn5	Prefoldin 5	Prefoldin 5 (Pfdn5) encodes a member of the alpha subunit of the heterohexameric prefoldin complex, which acts as chaperone protein. It is involved in the inhibition of the formation of ectopic neuroblasts. [Date last reviewed: 2021-01-21]
FBgn0038981	CG5346	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0038984	AdipoR	Adiponectin receptor	Adiponectin receptor (AdipoR) encodes a membrane protein that regulates glucose and lipid metabolism by controlling insulin signaling. It also maintains germ line stem cells via an insulin-independent mechanism. [Date last reviewed: 2018-11-08]
FBgn0038989	CG6937	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039003	wfs1	wolfram syndrome 1	wolfram syndrome 1 (wfs1) encodes an endoplasmic reticulum-resident transmembrane protein. Neuronal knockdown of wfs1 increases susceptibility to age- and stress-induced neuronal dysfunction and degeneration. [Date last reviewed: 2021-01-21]
FBgn0039004	Nup133	Nucleoporin 133kD	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039006	Cyp6d4	Cytochrome P450 6d4	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039013	CG4813	NA	NA
FBgn0039016	Dcr-1	Dicer-1	NA
FBgn0039017	CG6985	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0039019	HP1c	Heterochromatin Protein 1c	Heterochromatin Protein 1c (HP1c) encodes a chromatin binding protein that is involved in telomere capping and transcription regulation and interacts with the zinc-finger proteins encoded by woc and row. [Date last reviewed: 2019-03-07]
FBgn0039020	CG17141	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039022	Nepl13	Neprilysin-like 13	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039023	Nepl14	Neprilysin-like 14	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039024	Nepl15	Neprilysin-like 15	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039025	Usp12-46	Ubiquitin-specific protease 12/46	Ubiquitin-specific protease 12/46 (Usp12-46) encodes a deubiquitinating enzyme that negatively regulates the Notch signaling pathway. [Date last reviewed: 2018-11-08]
FBgn0039026	CG7029	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039044	p53	p53	p53 (p53) encodes a transcriptional factor required for adaptive responses to genotoxic stress, including cell death, compensatory proliferation and DNA repair. [Date last reviewed: 2019-03-14]
FBgn0039045	CG17119	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039049	CG6726	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039055	Rassf	Ras association family member	Ras association family member (Rassf) encodes a RASSF (ras-association domain family) protein that binds to the kinase encoded by hpo and promotes its dephosphorylation by the STRIPAK PP2A complex. [Date last reviewed: 2018-11-08]
FBgn0039056	CenB1A	Centaurin beta 1A	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039065	Rad60	Rad60	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039066	EloA	Elongin A	Elongin A (EloA) encodes a transcription elongation factor that enhances the catalytic rate of RNA Polymerase II by suppressing its transient pausing. It associates with the products of EloB and EloC. [Date last reviewed: 2019-03-07]
FBgn0039067	wda	will decrease acetylation	will decrease acetylation (wda) encodes a component of the highly conserved Spt-Ada-Gcn5 Acetyltransferase (SAGA) chromatin modifying complex. This complex is responsible for acetylation of histones and deubiquitination of the product of His2B at active promoters. The product of wda is a component of the histone-acetyltransferase (HAT) module, and is essential for full HAT activity of the the product of Gcn5. [Date last reviewed: 2019-03-21]
FBgn0039068	Pex11c	Peroxin 11c	NA
FBgn0039069	CG6763	NA	NA
FBgn0039073	CG4408	NA	NA
FBgn0039098	GILT3	Gamma-interferon-inducible lysosomal thiol reductase 3	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039099	GILT2	Gamma-interferon-inducible lysosomal thiol reductase 2	Gamma-interferon-inducible lysosomal thiol reductase 2 (GILT2) encodes a unique thiol reductase that catalyzes the disulfide bond reduction. It is involved in immune response against bacterial and viral challenge via JAK-STAT signaling pathway. [Date last reviewed: 2019-03-07]
FBgn0039101	CG16710	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039108	CG10232	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039109	CG10365	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039110	RanBP3	Ran binding protein 3	Ran binding protein 3 (RanBP3) encodes a chromosome region maintenance 1 (CRM1) cofactor involved in the export of proteins from the nucleus. It negatively regulates Wnt signalling. [Date last reviewed: 2019-09-12]
FBgn0039111	PTPMT1	Protein tyrosine phosphatase, mitochondrial 1	Protein tyrosine phosphatase, mitochondrial 1 (PTPMT1) encodes a key player in the biosynthesis of cardiolipin in the mitochondria. [Date last reviewed: 2019-03-14]
FBgn0039112	SdhD	Succinate dehydrogenase, subunit D	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039113	udt	undicht	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039114	Lsd-1	Lipid storage droplet-1	Lipid storage droplet-1 (Lsd-1) encodes a protein associated with lipid droplets. It protects lipid droplets from lipase mediated remobilization and facilitates lipolysis by serving as an anchoring point for lipases such as the one encoded by Hsl. It is involved in lipid storage amount regulation and energy homeostasis in concert with the product of Lsd-2. [Date last reviewed: 2019-03-14]
FBgn0039115	CG10214	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039116	CG10375	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0039117	tst	twister	twister (tst) encodes a protein that regulates mRNA alternative splicing [Date last reviewed: 2019-09-19]
FBgn0039118	CG10208	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039120	Nup98-96	Nucleoporin 98-96kD	Nucleoporin 98-96kD (Nup98-96) encodes a precursor protein that is cleaved into Nup98 and Nup96 proteins, two integral parts of the nuclear pore. In the male gonad, loss of Nup98-96 function results in premature differentiation of germ line cells at the expense of proliferation. [Date last reviewed: 2019-03-14]
FBgn0039125	Ndc1	Nuclear division cycle 1	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039126	CG13601	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039128	CG13599	NA	NA
FBgn0039130	CG5854	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039132	AP-1sigma	Adaptor Protein complex 1, sigma subunit	NA
FBgn0039135	CG13603	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039136	CG5902	NA	NA
FBgn0039137	Epp	Ecdysteroid phosphate phosphatase	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039139	Mettl3	Methyltransferase like 3	Methyltransferase like 3 (Mettl3) encodes an RNA N6-methyladenosine transferase that contributes to oogenesis, lifespan and behaviour, including flight, locomotion and grooming. [Date last reviewed: 2019-03-14]
FBgn0039140	Miro	Mitochondrial Rho	Mitochondrial Rho (Miro) encodes an atypical GTPase and Ca[2+] sensor on the outer mitochondrial membrane that is vital for mitochondrial homeostasis and microtubule-based mitochondrial transport. It mediates linkage to kinesin and dynein motors through interactions with Milton/TRAK adaptor proteins. [Date last reviewed: 2019-03-14]
FBgn0039141	spas	spastin	spastin (spas) encodes a member of the AAA ATPase family that assembles into hexamers and severs microtubules along their lengths. The microtubule binding and severing activities of the product of spas are dependent upon tubulin glutamylation levels. Its proposed roles include mitosis, axon transport, synapse formation, dendrite arborization, organelle tubulation, and lipid droplet metabolism. [Date last reviewed: 2018-11-08]
FBgn0039145	CG6000	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039149	CG18428	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-10-13]
FBgn0039150	CG13605	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039153	GatB	Glutamyl-tRNA amidotransferase, subunit B	NA
FBgn0039155	Kal1	Kallmann syndrome 1	NA
FBgn0039156	CG6178	NA	NA
FBgn0039157	Myo95E	Myosin 95E	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039158	TBC1d7	TBC1 domain family member 7	NA
FBgn0039159	mRpS24	mitochondrial ribosomal protein S24	NA
FBgn0039160	CG5510	NA	NA
FBgn0039163	CG5515	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039165	CG6204	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039167	CG17786	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-10-13]
FBgn0039169	Spps	Sp1-like factor for pairing sensitive-silencing	Sp1-like factor for pairing sensitive-silencing (Spps) encodes a zinc-finger protein in the Sp1/KLF family. It binds to Polycomb response elements, and is required for the recruitment of Polycomb group proteins to some of them. [Date last reviewed: 2019-03-14]
FBgn0039172	Spase22-23	Spase 22/23-subunit	NA
FBgn0039175	beta-PheRS	Phenylalanyl-tRNA synthetase, beta-subunit	Phenylalanyl-tRNA synthetase, β-subunit (β-PheRS) encodes a cytoplasmic aminoacyl-tRNA synthetase that catalyzes the ligation of Phenylalanine to its cognate tRNAPhe. Together with the α-subunit it forms a tetrameric enzyme complex. This subunit plays a role in recognition and binding of tRNAPhe and it provides the editing site that hydrolyzes wrongfully activated or ligated compounds. [Date last reviewed: 2019-03-21]
FBgn0039182	CG5728	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039183	Dis3	Dis3	Dis3 (Dis3) encodes an exoribonuclease that forms part of the RNA processing exosome complex. It is involved in the regulation of cell cycle progresion, microRNA expression and mRNA surveillance. [Date last reviewed: 2019-09-12]
FBgn0039186	CG5746	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039187	CG6454	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039188	Golgin84	Golgin-84	NA
FBgn0039189	CG18528	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039204	CG6607	NA	NA
FBgn0039205	CG13623	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039207	Cftr	CF transmembrane conductance regulator	NA
FBgn0039209	REPTOR	Repressed by TOR	Repressed by TOR (REPTOR) encodes a transcription factor that shuttles between cytoplasm and nucleus depending on the state of the activity of the product of Tor. Together with its binding partner encoded by REPTOR-BP, it mediates much of the transcriptional response observed upon Tor complex 1 inhibition. [Date last reviewed: 2019-03-14]
FBgn0039210	CG13625	NA	NA
FBgn0039212	Syx18	Syntaxin 18	Syntaxin 18 (Syx18) encodes a SNAP receptor involved in neuromuscular synaptic transmission. [Date last reviewed: 2019-07-11]
FBgn0039213	atl	atlastin	atlastin (atl) encodes a dynamin-like membrane-bound GTPase that mediates endoplasmic reticulum membrane fusion in a GTP-dependent fashion. It is required for normal growth of muscles and synapses at the neuromuscular junction. [Date last reviewed: 2018-11-08]
FBgn0039214	puf	puffyeye	puffyeye (puf) encodes an essential deubiquitinating enzyme that acts as a ubiquitin-specific protease. It removes ubiquitin polypeptide chains from the products of Myc and CycE, thereby stabilizing these proteins and increasing their abundance to influence cell growth and proliferation. The product of puf binds to the product of ago as well as its substrates. It antagonizes ago function. [Date last reviewed: 2019-03-14]
FBgn0039215	CG6695	NA	NA
FBgn0039218	Polr2L	RNA polymerase II, I and III subunit L	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039219	CG13630	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039223	CG5805	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039226	Ude	Uracil-DNA degrading factor	Uracil-DNA degrading factor (Ude) encodes a DNA-processing enzyme with uracil-DNA-degrading activity. [Date last reviewed: 2019-03-14]
FBgn0039227	polybromo	polybromo	polybromo (polybromo) encodes a subunit of Polybromo-associated Brahma complex (PBAP). Its main biological role is involved in chromatin remodeling together with Brahma complex. It can also regulate gene transcription through DNA binding, which is dependent or independent ofthe PBAP complex. [Date last reviewed: 2019-03-21]
FBgn0039229	Saf-B	Scaffold attachment factor B	NA
FBgn0039233	CG7006	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039234	Nct	Nicastrin	Nicastrin (Nct) encodes a transmembrane protein that is a key component of the γ-secretase, the protease complex for proteolytic cleavage of the Notch signaling receptor. [Date last reviewed: 2018-11-08]
FBgn0039240	CG3744	NA	NA
FBgn0039249	CG11168	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039250	Mink	Mitotic spindle and nuclear protein	NA
FBgn0039252	CG11771	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039254	Nmnat	Nicotinamide mononucleotide adenylyltransferase	Nicotinamide mononucleotide adenylyltransferase (Nmnat) encodes an essential enzyme in the NAD salvage pathway, catalyzing the last step of NAD synthesis. It is also a neuronal maintenance factor that protects neurons from excitotoxicity, environmental stress and protein misfolding induced degeneration. [Date last reviewed: 2019-03-14]
FBgn0039257	tnc	tenectin	NA
FBgn0039258	beta4GalT7	beta-4-galactosyltransferase 7	β-4-galactosyltransferase 7 (β4GalT7) encodes an enzyme that transfers a Gal to the Xyl-O-Ser in the tetrasaccharide structure of the protein-linkage region of glycosaminoglycans (GAGs). It is involved in Hh and Dpp signaling pathways mediated by GAGs in development. [Date last reviewed: 2019-03-21]
FBgn0039259	EMC6	ER membrane protein complex subunit 6	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039260	Smg6	Smg6	Smg6 (Smg6) encodes an RNA endonuclease that is required for nonsense mediated mRNA decay (NMD). Upon recognition of an NMD-targeted transcript, it cleaves the mRNA in the vicinity of the termination codon, exposing free 5' and 3' ends leading to the complete exonucleolytic degradation of the target. [Date last reviewed: 2018-11-08]
FBgn0039261	Ythdf	YTH N6-methyladenosine RNA binding protein	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039265	CG11790	NA	NA
FBgn0039266	CG11791	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-10-13]
FBgn0039269	veli	veli	veli (veli) encodes a protein involved in border follicle cell migration and regulation of synaptic growth at the neuromuscular junction. [Date last reviewed: 2019-09-19]
FBgn0039270	PQBP1	Poly-glutamine tract binding protein 1	Poly-glutamine tract binding protein 1 (PQBP1) encodes a component of nuclear speckles and cytoplasmic stress granules. It is involved in RNA transcription, RNA splicing, and possibly in protein translation. [Date last reviewed: 2019-03-14]
FBgn0039271	CG11839	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039273	shams	shams	shams (shams) encodes a xylosyltransferase involved in protein O-linked glycosylation and Notch signalling regulation. [Date last reviewed: 2019-09-12]
FBgn0039274	CG11920	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039290	CG13654	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039291	CG13663	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0039293	Alg9	ALG9, alpha-1,2-mannosyltransferase	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039294	Cad96Cb	Cadherin 96Cb	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039296	Sil1	Sil1 nucleotide exchange factor	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039300	RpS27	Ribosomal protein S27	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039301	Nup37	Nucleoporin 37kD	NA
FBgn0039302	Nup358	Nucleoporin 358kD	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039303	CG11857	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039304	CG10425	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039305	CG11858	NA	NA
FBgn0039306	RIOK2	RIO kinase 2	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039321	CG10550	NA	NA
FBgn0039323	CG10559	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039328	CHKov2	CHK domain ov2	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039329	CG10669	NA	NA
FBgn0039335	Vps33B	Vacuolar protein sorting 33B	Vacuolar protein sorting 33B (Vps33B) encodes a member of the family of SM proteins, which in conjunction with SNARE proteins catalyze membrane fusion events. The product of Vps33B, together with its binding partner encoded by Vps16B, forms a complex that is necessary for fusions between phagosomes and lysosomes. [Date last reviewed: 2018-11-08]
FBgn0039336	CG4553	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0039337	MED28	Mediator complex subunit 28	NA
FBgn0039338	XNP	XNP	XNP (XNP) encodes two protein isoforms that participate in the maintenance of heterochromatin and chromosomal stability. They interact with heterochromatin proteins such as those encoded by Su(var)205 and ADD1. [Date last reviewed: 2018-11-08]
FBgn0039339	CG5116	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039341	CG5112	NA	NA
FBgn0039348	Npl4	Nuclear protein localization 4	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039349	Ssadh	Succinic semialdehyde dehydrogenase	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039350	jigr1	jing interacting gene regulatory 1	jing interacting gene regulatory 1 (jigr1) encodes a nuclear protein that is differentially expressed in the embryonic central nervous system and highly expressed in neurons and glial cells in the larval nervous system. Its expression is downregulated in larval neuroblasts by the miR-92 family to maintain the neuroblast pool. [Date last reviewed: 2018-11-08]
FBgn0039354	Lgr3	Leucine-rich repeat-containing G protein-coupled receptor 3	Leucine-rich repeat-containing G protein-coupled receptor 3 (Lgr3) encodes a protein activated by the relaxin-like hormone encoded by Ilp8, which coordinates organ growth. [Date last reviewed: 2019-03-14]
FBgn0039355	CG4730	NA	NA
FBgn0039357	CG4743	NA	NA
FBgn0039358	CG5028	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039359	RpL27	Ribosomal protein L27	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039360	CLS	Cardiolipin synthase	Cardiolipin synthase (CLS) encodes a protein that catalyzes the condensation of CDP-diacylglycerol and phosphatidylglycerol to cardiolipin, a specific phospholipid of mitochondria. [Date last reviewed: 2019-03-07]
FBgn0039379	CG5886	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039381	SppL	Signal peptide peptidase-like	NA
FBgn0039385	CG5913	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039402	Vps2	Vacuolar protein sorting 2	Vacuolar protein sorting 2 (Vps2) encodes a component of the ESCRT-III complex which is required for endosome-mediated trafficking via multivesicular body formation and sorting. [Date last reviewed: 2021-01-21]
FBgn0039403	Sld5	Sld5	Sld5 (Sld5) encodes a subunit of the Cdc45/Mcm2-7/GINS (CMG) complex, which is associated with an ATP-dependent DNA helicase function and is involved in the regulation of the mitotic G1/S transition. [Date last reviewed: 2019-09-19]
FBgn0039404	CG14543	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039406	RpL34a	Ribosomal protein L34a	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039407	CG14544	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039417	CG6073	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039419	CG12290	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039427	CG5447	NA	NA
FBgn0039430	CG5455	NA	NA
FBgn0039431	plum	plum	plum (plum) encodes an Ig-superfamily transmembrane protein. It is required for developmental pruning of both mushroom body neurons and motor neurons via TGF-β signaling. plum genetically interacts with myo and babo. [Date last reviewed: 2019-03-14]
FBgn0039449	CG6425	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039450	Yif1	Yip1d-interacting factor 1	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039451	CG6420	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0039459	IntS12	Integrator 12	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039461	CG5500	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0039462	CG14252	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039464	CG6330	NA	NA
FBgn0039465	Tsp97E	Tetraspanin 97E	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039466	CG5521	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039467	CG14253	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039479	CG14257	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-10-13]
FBgn0039485	CG17189	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039487	gb	genderblind	genderblind (gb) encodes an amino acid transporter involved in glutamate secretion into the extracellular space. It regulates synaptic transmission and male courtship behavior by altering glutamate receptor abundance in the nervous system. [Date last reviewed: 2019-03-07]
FBgn0039488	CG6066	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039489	CG5880	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039492	CG6051	NA	NA
FBgn0039494	grass	Gram-positive Specific Serine protease	Gram-positive Specific Serine protease (grass) encodes a secreted serine protease that is involved downstream of the microbial sensing receptors encoded by GNBP3 and PGRP-SA in the activation of the Toll pathway during the immune response. It functions downstream of the serine protease encoded by modSP and upstream of the enzyme encoded by SPE, which cleaves the product of spz. [Date last reviewed: 2019-03-07]
FBgn0039501	TTLL6B	Tubulin tyrosine ligase-like 6B	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039505	CG5934	NA	NA
FBgn0039507	mrt	martik	NA
FBgn0039508	CG3368	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0039509	bigmax	bigmax	bigmax (bigmax) encodes a basic helix-loop-helix-leucine zipper transcription factor. Together with its binding partner encoded by Mondo, the product of bigmax is involved in sugar-dependent gene regulation. It is involved in transcriptional control of many metabolic pathways, including glycolysis, de novo lipogenesis and the pentose phosphate pathway. Loss of bigmax function produces dietary sugar intolerance. [Date last reviewed: 2019-03-07]
FBgn0039525	CG5646	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039528	dsd	distracted	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039530	Tusp	Tusp	Tusp (Tusp) encodes a protein involved in SNARE complex assembly. [Date last reviewed: 2019-09-19]
FBgn0039531	CG5611	NA	NA
FBgn0039532	Mtl	Mig-2-like	Mig-2-like (Mtl) encodes a Rho GTPase involved in actin organization regulation. It contributes to multiple actin-mediated processes including dorsal closure, wound healing, cell migration, germ band shortening and salivary gland morphogenesis. [Date last reviewed: 2019-08-01]
FBgn0039537	Hsdl2	Hydroxysteroid dehydrogenase like 2	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039538	CG12883	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-10-13]
FBgn0039543	CROT	Carnitine O-octanoyltransferase	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039544	CG12877	NA	NA
FBgn0039554	CG5003	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039555	mRpS22	mitochondrial ribosomal protein S22	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039557	CG12259	NA	NA
FBgn0039558	BCAS2	BCAS2	BCAS2 (BCAS2) encodes an essential protein that regulates wing development via Delta-Notch signaling. [Date last reviewed: 2018-11-08]
FBgn0039559	NSD	Nuclear receptor binding SET domain protein	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039560	BOD1	Biorientation Defective 1	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039561	mfrn	mitoferrin	NA
FBgn0039562	Gp93	Glycoprotein 93	Glycoprotein 93 (Gp93) encodes a heat shock protein Hsp90 family member that is involved in midgut development. [Date last reviewed: 2019-03-07]
FBgn0039563	CG4951	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039564	Nep7	Neprilysin 7	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039565	CG4884	NA	NA
FBgn0039566	CG4849	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039580	Gfat2	Glutamine:fructose-6-phosphate aminotransferase 2	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039581	Moca-cyp	Moca-cyp	Moca-cyp (Moca-cyp) encodes a peptidyl-prolyl cis-trans isomerase. [Date last reviewed: 2019-09-19]
FBgn0039588	mIF2	mitochondrial translation initiation factor 2	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039589	CG9986	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0039590	CG10011	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039593	Sid	Stress induced DNase	Stress induced DNase (Sid) encodes a protein belonging to an evolutionarily conserved enzyme family that degrades both single and double stranded nucleic acids. Sid expression is highly induced by bacterial infection and oxidative stress. Its apparent role is to protect from the toxic effects of excess DNA/RNA released by a vigorous immune response. [Date last reviewed: 2019-03-14]
FBgn0039600	Prp39	pre-mRNA processing factor 39	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039601	CG1523	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0039602	CG1647	NA	NA
FBgn0039612	Nepl19	Neprilysin-like 19	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039613	Nepl20	Neprilysin-like 20	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039622	eIF4E6	eukaryotic translation initiation factor 4E6	eukaryotic translation initiation factor 4E6 (eIF4E6) encodes a RNA 7-methylguanosine cap binding protein. [Date last reviewed: 2019-08-01]
FBgn0039623	CG1951	NA	NA
FBgn0039625	beta4GalNAcTB	beta1,4-N-acetylgalactosaminyltransferase B	β1,4-N-acetylgalactosaminyltransferase B (β4GalNAcTB) encodes a Golgi glycosyltransferase that transfers N-acetylgalactosamine to N-acetylglucosamine residues of glycosphingolipids. [Date last reviewed: 2019-03-21]
FBgn0039626	Slu7	Slu7	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039627	CG11837	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039631	Sirt7	Sirtuin 7	NA
FBgn0039632	Cul5	Cullin 5	Cullin 5 (Cul5) is expressed in both neuronal and non-neuronal cells (such as in fusion sites of embryonic trachea). Reduction of the product of Cul5 in neuronal cells results in an increase in number of synaptic boutons in the larval neuromuscular junction. [Date last reviewed: 2019-03-07]
FBgn0039633	Bicra	BRD4 interacting chromatin remodeling complex associated protein	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039634	alpha-Man-Ib	alpha-Mannosidase class I b	NA
FBgn0039635	Pdhb	Pyruvate dehydrogenase E1 beta subunit	NA
FBgn0039636	Atg14	Autophagy-related 14	Autophagy-related 14 (Atg14) encodes a protein involved in autophagy. [Date last reviewed: 2019-06-27]
FBgn0039637	Ctl2	Choline transporter-like 2	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039638	dgt6	dim gamma-tubulin 6	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039640	superdeath	Suppressor of ER stress-induced death	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039641	CG14511	NA	NA
FBgn0039642	CG11882	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-10-13]
FBgn0039644	rdog	red dog mine	NA
FBgn0039650	Mesh1	Metazoan SpoT homolog-1	Metazoan SpoT homolog-1 (Mesh1) encodes a structural and functional ortholog of bacterial protein SpoT. It hydrolyzes ppGpp to GDP. Its mutants show retarded growth in amino acid-starved media, suggesting the conserved role in stringent responses. [Date last reviewed: 2019-03-14]
FBgn0039651	Cyt-c1L	Cytochrome c1-like	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039654	Brd8	Bromodomain containing 8	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039663	CG2321	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039664	CG2006	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039665	CG2310	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039668	Trc8	TRC8 ring finger protein	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039674	CG1907	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039680	Cap-D2	CAP-D2 condensin subunit	CAP-D2 condensin subunit (Cap-D2) encodes a component of the conserved condensin I complex, together with the products of Cap-G, barr, SMC2 and glu. Condensin I associates with mitotic chromatin and plays a crucial role in shaping mitotic chromosomes and in their faithful segregation during anaphase. [Date last reviewed: 2019-03-07]
FBgn0039682	Obp99c	Odorant-binding protein 99c	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039687	Naa40	N(alpha)-acetyltransferase 40	NA
FBgn0039689	CIA30	Complex I intermediate-associated protein, 30 kDa	NA
FBgn0039690	Gnpnat	Glucosamine-phosphate N-acetyltransferase	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039691	IntS11	Integrator 11	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039694	fig	fos intronic gene	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039696	Rnb	R and B	NA
FBgn0039697	CG7834	NA	NA
FBgn0039698	CG7789	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039702	Vps16B	Vacuolar protein sorting 16B	Vacuolar protein sorting 16B (Vps16B) encodes a protein that, together with its binding partner encoded by Vps33B, forms a distinct complex necessary for fusions between phagosomes and lysosomes. [Date last reviewed: 2019-03-21]
FBgn0039705	Atg16	Autophagy-related 16	Autophagy-related 16 (Atg16) encodes a protein that forms an E3-like protein complex. This complex contributes to the the covalent binding of the lipid phosphatidylethanolamine to the product of Atg8a, a key autophagy protein involved in autophagosome biogenesis. The product of Atg16 is involved in autophagosome biogenesis, maintenance of proper neuromuscular function, lifespan, ethanol sedation, and enteroendocrine cell function in the intestine. [Date last reviewed: 2019-03-21]
FBgn0039710	dgt1	dim gamma-tubulin 1	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039711	CG7824	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039712	CG15514	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039713	RpS8	Ribosomal protein S8	Ribosomal protein S8 (RpS8) encodes a structural constituent of ribosomes that is involved in larval lymph gland hemopoiesis. [Date last reviewed: 2019-07-11]
FBgn0039714	Zip99C	Zinc/iron regulated transporter-related protein 99C	Zinc/iron regulated transporter-related protein 99C (Zip99C) encodes an iron transporter located on the Golgi and endoplasmic reticulum that moves iron from the cytoplasm into the secretory compartments. [Date last reviewed: 2019-03-21]
FBgn0039726	eIF2Balpha	eukaryotic translation initiation factor 2B subunit alpha	eukaryotic translation initiation factor 2B subunit alpha (eIF2Bα) encodes a regulatory subunit of the eIF2B heteropentamer. [Date last reviewed: 2019-08-01]
FBgn0039727	Vps13B	Vacuolar protein sorting 13B	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039730	CG7903	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039731	Sas-6	Spindle assembly abnormal 6	"Spindle assembly abnormal 6 (Sas-6) encodes a centriole protein that is essential for centriole assembly. It can homo-oligomerise to form a 9-fold symmetric ""cartwheel"" structure that plays an important part in setting the 9-fold symmetry of the assembling centriole. [Date last reviewed: 2019-03-14]"
FBgn0039732	CG15525	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0039733	CG11504	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039735	Nph	Nucleophosmin	Nucleophosmin (Nph) encodes a histone binding protein involved in chromatin remodeling and sperm chromatin decondensation. [Date last reviewed: 2019-09-12]
FBgn0039737	CG7920	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039738	Mgat2	Mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase	Mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase (Mgat2) encodes an enzyme involved in protein N-linked glycosylation. [Date last reviewed: 2019-09-26]
FBgn0039740	ZIPIC	Zinc-finger protein interacting with CP190	Zinc-finger protein interacting with CP190 (ZIPIC) encodes a promoter-binding transcription factor that displays architectural and insulator functions. [Date last reviewed: 2019-03-21]
FBgn0039741	CG7943	NA	NA
FBgn0039743	Jasper	JIL-1 anchoring and stabilizing protein	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039751	CG1983	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039756	CG9743	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039757	RpS7	Ribosomal protein S7	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039764	CG15535	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-10-13]
FBgn0039765	mRpS18C	mitochondrial ribosomal protein S18C	mitochondrial ribosomal protein S18C (mRpS18C) encodes a component of the small subunit of mitochondrial ribosomes, which translate mRNAs encoded by the mitochondrial genome. [Date last reviewed: 2019-03-21]
FBgn0039766	CG15536	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-10-13]
FBgn0039767	CG2218	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039773	CG2224	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039774	CDase	Ceramidase	Ceramidase (CDase) encodes a protein that has a cell non-autonomous function in maintaining membrane homeostasis. CDase targeted over-expression suppresses retinal degeneration in certain photoreceptor degeneration mutants. [Date last reviewed: 2019-03-07]
FBgn0039776	PH4alphaEFB	prolyl-4-hydroxylase-alpha EFB	NA
FBgn0039789	CG9717	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039790	CG2246	NA	NA
FBgn0039797	eIF4H2	eukaryotic translation initiation factor 4H2	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039798	CG11313	NA	NA
FBgn0039800	Npc2g	Niemann-Pick type C-2g	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039801	Npc2h	Niemann-Pick type C-2h	Niemann-Pick type C-2h (Npc2h) encodes a protein involved in immune signaling via interaction with lipopolysaccharides, lipid A, peptidoglycan and lipoteichoic acid. [Date last reviewed: 2019-09-26]
FBgn0039802	dj-1beta	dj-1beta	NA
FBgn0039804	CG15544	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039808	CG12071	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039809	CG15547	NA	NA
FBgn0039827	CG1544	NA	NA
FBgn0039828	CG1542	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039829	CG15561	NA	NA
FBgn0039830	ATPsynC	ATP synthase, subunit C	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039831	CG12054	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039835	mRpL32	mitochondrial ribosomal protein L32	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039836	CG1750	NA	NA
FBgn0039844	CG1607	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039846	PNPase	Polynucleotide phosphorylase	Polynucleotide phosphorylase (PNPase) encodes an enzyme involved in the regulation of mitochondrial mRNA stability. [Date last reviewed: 2019-09-19]
FBgn0039849	CG11334	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039854	CG1635	NA	NA
FBgn0039857	RpL6	Ribosomal protein L6	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039858	CycG	Cyclin G	Cyclin G (CycG) encodes a protein that belongs to the atypical cyclins. It interacts with diverse proteins such as the product of H, β-subunits of PP2a, the 9-1-1 complex, cyclin-dependent kinases and Enhancer of Trithorax and Polycomb proteins. The product of CycG contributes to DNA repair, cell cycle regulation, growth and metabolism, epigenetic gene regulation and developmental stability. [Date last reviewed: 2019-03-07]
FBgn0039859	Mnat9	microtubule-associated Nat9	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039860	CG1792	NA	NA
FBgn0039861	pasha	partner of drosha	partner of drosha (pasha) encodes a protein involved in oogenesis and miRNA processing. [Date last reviewed: 2019-09-19]
FBgn0039862	kek6	kekkon 6	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039863	CG1815	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039867	CstF50	Cleavage stimulation factor 50 kD subunit	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039868	CG11563	NA	NA
FBgn0039869	CG1890	NA	NA
FBgn0039870	CG1896	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039875	sip3	septin interacting protein 3	septin interacting protein 3 (sip3) encodes a transmembrane protein in the endoplasmic reticulum (ER) membrane with ubiquitin ligase activity. It promotes the degradation of misfolded peptides by retro-translocating them from the ER lumen to the cytoplasm and sending them for proteasomal degradation via ubiquitylation. [Date last reviewed: 2019-03-14]
FBgn0039876	CG2126	NA	NA
FBgn0039877	Mccc1	Methylcrotonoyl-CoA carboxylase 1	Methylcrotonoyl-CoA carboxylase 1 (Mccc1) encodes the biotin-attachment subunit of the 3-methylcrotonyl-CoA carboxylase. It catalyzes the conversion of 3-methylcrotonyl-CoA to 3-methylglutaconyl-CoA, a critical step for leucine and isovaleric acid catabolism. [Date last reviewed: 2019-03-14]
FBgn0039881	CG1971	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-10-13]
FBgn0039882	Rift	Riboflavin transporter	NA
FBgn0039883	RhoGAP100F	Rho GTPase activating protein at 100F	NA
FBgn0039886	CG2003	NA	NA
FBgn0039889	Arl4	ADP ribosylation factor-like 4	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039890	Abcd1	ATP binding cassette subfamily D member 1	NA
FBgn0039896	yellow-h	yellow-h	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039897	CG1674	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039902	Zip102B	Zinc/iron regulated transporter-related protein 102B	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039904	Hcf	Host cell factor	NA
FBgn0039907	lgs	legless	legless (lgs) encodes a conserved transcriptional cofactor of the product of arm that is essential for the transcription of Wingless target genes. It contributes to growth regulation, cell survival and developmental patterning. [Date last reviewed: 2019-03-14]
FBgn0039908	Asator	Asator	Asator (Asator) encodes a tau-tubulin kinase homolog that is localized to the cytoplasm at interphase. It directly interacts with the spindle matrix protein encoded by Mtor and localizes to the spindle region during mitosis. [Date last reviewed: 2019-05-16]
FBgn0039909	ND-49	NADH dehydrogenase (ubiquinone) 49 kDa subunit	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039911	CG1909	NA	NA
FBgn0039914	mav	maverick	maverick (mav) encodes a protein involved in the BMP signaling pathway. [Date last reviewed: 2019-09-26]
FBgn0039920	CG11360	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039923	MED26	Mediator complex subunit 26	NA
FBgn0039924	PIP4K	Phosphatidylinositol 5-phosphate 4-kinase	Phosphatidylinositol 5-phosphate 4-kinase (PIP4K) encodes an enzyme that mediates the conversion of phosphatidylinositol 4 phosphate to phosphatidylinositol 4,5 bisphosphate. It has been implicated in the regulation of mTOR signalling and control of cell size. [Date last reviewed: 2019-03-14]
FBgn0039925	Kif3C	Kinesin family member 3C	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039927	CG11155	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039928	Cals	Calsyntenin-1	NA
FBgn0039929	CG11076	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039930	CG11077	NA	NA
FBgn0039932	fuss	fussel	fussel (fuss) encodes a protein that belongs to the highly conserved Sno/Ski family of Smad binding proteins. fuss mutant phenotypes in the larval brain phenocopy babo and Smox mutants, suggesting a role in Activin signaling. fuss overexpression antagonizes both Dpp and Activin signaling. [Date last reviewed: 2019-03-07]
FBgn0039936	Gyf	Gigyf	Gigyf (Gyf) encodes a protein that is necessary for maintenance of neuromuscular homeostasis. It regulates protein translation, insulin/IGF signaling pathway and autophagy. [Date last reviewed: 2019-03-21]
FBgn0039938	Sox102F	Sox102F	Sox102F (Sox102F) encodes a transcription factor in the Sox gene family that regulates the Wnt signaling pathway. Its roles include heart development and cardiac function, and wing vein development and patterning. [Date last reviewed: 2019-03-14]
FBgn0039941	CG17167	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039942	CG17163	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-10-13]
FBgn0039943	CG17168	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039946	ATbp	(A+T)-stretch binding protein	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039955	CG41099	NA	NA
FBgn0039958	CG12567	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039965	Coa7	Cytochrome c oxidase assembly factor 7	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039966	Rab21	Rab21	NA
FBgn0039969	Fis1	Fission, mitochondrial 1	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039970	CG17508	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039972	Marf1	Meiosis regulator and mRNA stability factor 1	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039977	Spf30	Splicing factor 30	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039979	CR40282	NA	NA
FBgn0039993	CG17691	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0039994	conu	conundrum	conundrum (conu) encodes a Rho GTPase activating protein (RhoGAP) that negatively regulates Rho1 activity at the cell cortex via interaction with the product of Moe. [Date last reviewed: 2019-03-21]
FBgn0040005	CG17883	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0040007	RpL38	Ribosomal protein L38	Ribosomal protein L38 (RpL38) encodes a component of the large subunit of cytoplasmic ribosomes, which translate mRNAs encoded by the nuclear genome. RpL38 is haploinsufficient - heterozygous mutants display the 'Minute' phenotype, characterized by a slower developmental rate and small adult bristles. [Date last reviewed: 2019-03-14]
FBgn0040009	CG17490	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0040010	CG17493	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0040011	Slmap	Sarcolemma associated protein	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0040020	MED21	Mediator complex subunit 21	NA
FBgn0040022	Set1	SET domain containing 1	SET domain containing 1 (Set1) encodes an enzyme that methylates histone H3 on lysine 4 at promoter-proximal regions of most RNA Polymerase II transcribed genes. It is the catalytic subunit of the COMPASS complex. [Date last reviewed: 2019-03-14]
FBgn0040056	CG17698	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0040064	yip2	yippee interacting protein 2	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0040066	wds	will die slowly	NA
FBgn0040068	Vav	Vav guanine nucleotide exchange factor	Vav guanine nucleotide exchange factor (Vav) encodes a protein that belongs to the Dbl GEF superfamily. It functions as a GDP/GTP exchange factor for the product of Rac1 and an adaptor protein. Both activities are activated by direct tyrosine phosphorylation. [Date last reviewed: 2019-03-21]
FBgn0040070	Trx-2	thioredoxin-2	NA
FBgn0040071	tara	taranis	taranis (tara) encodes a transcriptional co-regulator that interacts with chromatin remodeling complexes, cell cycle proteins, and the JNK signaling pathway. It contributes to sleep, neural progenitor proliferation, and cell fate maintenance. [Date last reviewed: 2019-03-14]
FBgn0040075	rept	reptin	NA
FBgn0040078	pont	pontin	pontin (pont) encodes a member of the AAA+ (ATPases Associated with various cellular Activities) family. It is found in different complexes involved in transcriptional regulation, chromatin remodelling, DNA repair or ribonucleoprotein assembly, and participates in the control of cell proliferation and survival. [Date last reviewed: 2019-03-21]
FBgn0040079	pkaap	pkaap	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0040080	pins	partner of inscuteable	partner of inscuteable (pins) encodes a GDP-dissociation inhibitor involved in asymmetric cell division and mitotic spindle orientation. [Date last reviewed: 2019-06-13]
FBgn0040087	p115	p115	p115 (p115) encodes a key protein of the early secretory pathway where it interacts with the product of GM130 and Rab proteins. p115 depletion from S2 cells leads to a fragmentation of the Golgi but without impairing transport efficiency. [Date last reviewed: 2019-03-14]
FBgn0040089	meso18E	meso18E	NA
FBgn0040091	Ugt317A1	UDP-glycosyltransferase family 317 member A1	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0040099	lectin-28C	lectin-28C	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0040153	l(1)G0469	lethal (1) G0469	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0040206	krz	kurtz	kurtz (krz) encodes a β-arrestin (non-visual arrestin) involved in the desensitization and endocytic internalization of G protein coupled receptors, thus downregulating their activity. It also controls other signaling pathways, including Notch, receptor tyrosine kinase, Hedgehog, and Toll. It is required maternally for normal embryonic patterning and zygotically for larval viability. [Date last reviewed: 2019-03-14]
FBgn0040207	kat80	katanin 80	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0040208	Kat60	Katanin 60	Katanin 60 (Kat60) encodes a microtubule depolymerase involved in multiple microtubule-related processes including chromatid segregation, cell migration and dendrite development. [Date last reviewed: 2019-03-14]
FBgn0040212	Gnpat	Glyceronephosphate O-acyltransferase	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0040227	eIF3d1	eukaryotic translation initiation factor 3 subunit d1	NA
FBgn0040228	DCTN5-p25	Dynactin 5, p25 subunit	Dynactin 5, p25 subunit (DCTN5-p25) encodes a motor protein involved in spermatogenesis. It also contributes to the dendritic restriction of the product of Dscam1. [Date last reviewed: 2019-08-01]
FBgn0040230	dbo	diablo	NA
FBgn0040232	cmet	CENP-meta	CENP-meta (cmet) encodes a kinetochore kinesin that contributes to metaphase chromosome alignment. [Date last reviewed: 2019-06-27]
FBgn0040234	c12.2	c12.2	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0040235	c12.1	c12.1	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0040236	c11.1	c11.1	NA
FBgn0040238	Best1	Bestrophin 1	Bestrophin 1 (Best1) encodes a Ca-activated Cl channel. In Drosophila S2 cells, the current of the product of Best1 is activated by calcium and by cell swelling and plays a role in cell volume regulation. [Date last reviewed: 2019-03-07]
FBgn0040239	bc10	bc10	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0040250	Ugt304A1	UDP-glycosyltransferase family 304 member A1	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0040251	Ugt302K1	UDP-glycosyltransferase family 302 member K1	UDP-glycosyltransferase family 302 member K1 (Ugt302K1) encodes a UDP-glucosyltransferase. [Date last reviewed: 2019-03-14]
FBgn0040256	Ugt35C1	UDP-glycosyltransferase family 35 member C1	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0040259	Ugt302C1	UDP-glycosyltransferase family 302 member C1	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0040260	Ugt37D1	UDP-glycosyltransferase family 37 member D1	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0040262	Ugt37C2	UDP-glycosyltransferase family 37 member C2	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0040268	Top3alpha	Topoisomerase 3alpha	Topoisomerase 3α (Top3α) encodes a type IA topoisomerase that works with the helicase encoded by Blm to perform double Holliday junction dissolution during homologous recombination. It is also involved in DNA disentangling during chromosome segregation and mitochondrial DNA replication. [Date last reviewed: 2019-03-14]
FBgn0040271	Sulf1	Sulfated	Sulfated (Sulf1) encodes a heparan sulfate modifying enzyme, which extracellularly removes specific 6-O-sulfate groups from heparan sulfate in a post-synthetic manner. It regulates Wg signaling by reducing extracellular wg protein levels. It also regulates Hh signaling by acting as a positive regulator in cells producing the product of hh and a negative regulator in cells receiving the product of hh. [Date last reviewed: 2019-03-14]
FBgn0040273	Spt5	Spt5	NA
FBgn0040283	SMC1	Structural maintenance of chromosomes 1	Structural maintenance of chromosomes 1 (SMC1) encodes an ATPase that heterodimerizes with the product of SMC3 to interact with the products of vtd and SA to form the cohesin ring complex. Cohesin encircles sister chromatids after DNA replication and has multiple roles in the regulation of gene expression and DNA repair. [Date last reviewed: 2019-03-14]
FBgn0040285	Scamp	Scamp	NA
FBgn0040290	RecQ4	RecQ4 helicase	RecQ4 helicase (RecQ4) encodes an important protein for genome stability and DNA metabolism. It can utilize energy from ATP hydrolysis to help the DNA strand separation and exchange, playing a critical role in replication and repair. [Date last reviewed: 2019-03-14]
FBgn0040294	POSH	Plenty of SH3s	Plenty of SH3s (POSH) encodes a scaffold protein that regulates TNF-JNK signaling pathway. [Date last reviewed: 2019-07-11]
FBgn0040297	Nhe2	Na[+]/H[+] hydrogen exchanger 2	Na[+]/H[+] hydrogen exchanger 2 (Nhe2) encodes a Na-H exchanger of the SLC family 9A that increases intracellular pH. The product of Nhe2 activity promotes proliferation, morphogenesis and planar cell polarity, and contributes to oncogene-induced metastatic cell behaviors. [Date last reviewed: 2019-09-26]
FBgn0040298	Myt1	Myt1	NA
FBgn0040299	Myo28B1	Myosin 28B1	Myosin 28B1 (Myo28B1) encodes a high duty ratio motor protein belonging to the MyTH4-FERM subgroup of actin-based molecular motors. [Date last reviewed: 2019-03-21]
FBgn0040305	MTF-1	Metal response element-binding Transcription Factor-1	Metal response element-binding Transcription Factor-1 (MTF-1) encodes a zinc finger protein that primarily controls the homeostasis of physiological trace metals, such as zinc and copper, and the detoxification of non-essential, toxic heavy metals, such as cadmium, mercury, and silver. It activates a number of genes in response to heavy metal load but also induces transcription of the copper importer encoded by Ctr1B upon copper depletion. Variations in the DNA binding site can affect its response to a specific metal. [Date last reviewed: 2019-03-14]
FBgn0040308	Jafrac2	Thioredoxin peroxidase 2	Thioredoxin peroxidase 2 (Jafrac2) encodes an atypical 2-Cys peroxiredoxin that regulates hydrogen peroxide levels and participates in the formation of disulfide bonds during oxidative protein folding. [Date last reviewed: 2019-03-21]
FBgn0040309	Jafrac1	thioredoxin peroxidase 1	NA
FBgn0040319	Gclc	Glutamate-cysteine ligase catalytic subunit	Glutamate-cysteine ligase catalytic subunit (Gclc) encodes a heterodimeric enzyme involved in the first rate-limiting step of glutathione synthesis. It binds L-cysteine and L-glutamate to form gamma-glutamylcysteine. [Date last reviewed: 2019-03-21]
FBgn0040321	GNBP3	Gram-negative bacteria binding protein 3	Gram-negative bacteria binding protein 3 (GNBP3) encodes a hemolymphatic protein involved in the sensing of glucan (a fungal cell wall component) upstream of the Toll pathway. [Date last reviewed: 2019-03-07]
FBgn0040322	GNBP2	Gram-negative bacteria binding protein 2	NA
FBgn0040323	GNBP1	Gram-negative bacteria binding protein 1	Gram-negative bacteria binding protein 1 (GNBP1) encodes a hemolymphatic protein that participates together with the product of PGRP-SA in the activation of the Toll pathway by peptidoglycans, a cell-wall component of bacteria. [Date last reviewed: 2019-03-07]
FBgn0040324	Ephrin	Ephrin	Ephrin (Ephrin) encodes the ligand of the product of Eph. It is involved in nervous system development. [Date last reviewed: 2019-06-13]
FBgn0040333	brv3	brivido-3	NA
FBgn0040334	Tsp3A	Tetraspanin 3A	Tetraspanin 3A (Tsp3A) encodes a member of the tetraspanin superfamily. With two other tetraspanins, encoded by Tsp26A and Tsp86D, it regulates the trafficking of the product of kuz and consequently Notch signaling and several Notch-dependent developmental processes. [Date last reviewed: 2019-03-14]
FBgn0040336	Seipin	Seipin	Seipin (Seipin) encodes a transmembrane protein with roles in ER calcium homeostasis and lipid storage. [Date last reviewed: 2019-03-14]
FBgn0040337	CG3021	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0040339	MED22	Mediator complex subunit 22	NA
FBgn0040340	TRAM	TRAM	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0040344	Lztr1	Leucine zipper like transcription regulator 1	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0040346	CG3704	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0040347	mus81	mus81	mus81 (mus81) encodes the catalytic subunit of the Mus81-mms4 structure-selective endonuclease that functions in DNA repair. [Date last reviewed: 2019-03-14]
FBgn0040348	CG3703	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0040364	CG11378	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0040366	CG11398	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0040372	G9a	G9a	G9a (G9a) encodes a histone-lysine methyltransferase involved in epigenetic regulation. It contributes to multiple processes including gene expression, dendrite morphogenesis, larval locomotory behavior as well as short and long-term memory. [Date last reviewed: 2019-03-07]
FBgn0040373	CG3038	NA	NA
FBgn0040375	CG13760	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0040382	CG5273	NA	NA
FBgn0040383	CG5254	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0040384	CG32795	NA	NA
FBgn0040388	boi	brother of ihog	brother of ihog (boi) encodes a transmembrane protein that binds to the product of hh. The products of boi and ihog promote Hh signaling in receiving cells by acting as a co-receptor for the effector protein encoded by ptc. The product of boi also can suppress Hh signaling through a sequestration and release mechanism in cells producing the product of hh. It regulates many hh-dependent processes including proliferation, cell fate specification, and patterning. [Date last reviewed: 2019-03-07]
FBgn0040389	mRpL14	mitochondrial ribosomal protein L14	NA
FBgn0040394	CG16903	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0040395	Unc-76	Uncoordinated 76	Unc-76 (Unc-76) encodes a kinesin binding protein involved in axo-dendritic transport. [Date last reviewed: 2019-09-19]
FBgn0040396	CG3939	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0040397	CG3655	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0040398	CG14629	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0040465	Dlip3	Dorsal interacting protein 3	Dorsal interacting protein 3 (Dlip3) encodes a transcription factor whose loss of function in the eye disc results in the appearance of extra photoreceptors. Dlip3 overexpression in the early eye disc results in antennal duplication and eye-to-antennal transformation. [Date last reviewed: 2019-03-07]
FBgn0040466	Dlip2	Dorsal interacting protein 2	NA
FBgn0040467	Dlip1	Dorsal interacting protein 1	NA
FBgn0040475	SH3PX1	SH3 and PX domain containing 1	NA
FBgn0040477	cid	centromere identifier	centromere identifier (cid) encodes a centromere-specific histone H3 variant. The nucleosomes containing the product of cid function as an epigenetic mark for centromere identity, and initiate an assembly process that recruits additional centromere proteins (like the product of Cenp-C) as well as kinetochore proteins at the start of mitotic and meiotic divisions. [Date last reviewed: 2019-03-07]
FBgn0040493	grsm	granny smith	granny smith (grsm) encodes a member of the M17 family of leucine aminopeptidases, a family of proteases broadly involved in a number of cellular processes. High throughput transcriptomic and proteomic analyses have implicated the product of grsm in the regulation of immune-, nervous- and immune-related processes. [Date last reviewed: 2019-03-21]
FBgn0040505	Alk	Anaplastic lymphoma kinase	Anaplastic lymphoma kinase (Alk) encodes a protein that employs Ras/ERK and PI3K signalling pathways to function in multiple contexts including embryonic visceral muscle development, growth and organ size regulation, retinal axon targeting, modulation of neuromuscular transmission as well as sleep regulation and olfactory learning. Its ligand is the secreted protein encoded by jeb. [Date last reviewed: 2019-03-07]
FBgn0040512	zetaCOP	Coat Protein (coatomer) zeta	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0040529	COX7A	Cytochrome c oxidase subunit 7A	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0040534	Sf3b5	Splicing factor 3b subunit 5	Splicing factor 3b subunit 5 (Sf3b5) encodes a subunit of the histone modifying complex SAGA and the SF3B complex. The latter forms part of the larger U2 snRNP and is required for mRNA splicing. [Date last reviewed: 2019-03-21]
FBgn0040600	CG13631	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0040602	CG14545	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0040609	CG3348	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0040636	CG13255	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0040650	CG15456	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0040660	CG13551	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0040666	CG12848	NA	NA
FBgn0040670	e(y)2b	enhancer of yellow 2b	NA
FBgn0040751	CG13018	NA	NA
FBgn0040752	Prosap	Prosap	Prosap (Prosap) encodes a member of SH3 and multiple ankyrin repeat domain (SHANK) family of genes that encode synaptic scaffolding proteins. It regulates synaptic growth and development, including the structure of the neuromuscular junction and synapses of the calyx, and olfactory acuity. [Date last reviewed: 2019-03-21]
FBgn0040754	CG17059	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0040765	luna	luna	NA
FBgn0040773	COX7C	Cytochrome c oxidase subunit 7C	Cytochrome c oxidase subunit 7C (COX7C) encodes a negative regulator of neuroblast proliferation. [Date last reviewed: 2019-09-19]
FBgn0040777	CG14767	NA	NA
FBgn0040793	CG7630	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0040827	CG13315	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0040837	CG8620	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0040890	ksh	kish	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0040899	CG17776	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0040907	mRpL33	mitochondrial ribosomal protein L33	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0040918	schlank	schlank	schlank (schlank) encodes a member of the Ceramide Synthases family involved in sphingolipid metabolism. It is essential for ceramide synthesis and modulates triacylglycerol levels and transcriptional expression of body fat metabolism regulators. [Date last reviewed: 2019-03-14]
FBgn0040929	CG12659	NA	NA
FBgn0040931	CG9034	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0040942	CG12643	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0040964	CG18661	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0040985	CG6115	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0041004	CG17715	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0041087	wun2	wunen-2	wunen-2 (wun2) encodes a lipid phosphate phosphatase, an enzyme with an active site predicted to face extracellularly. It is required for germ cell migration and survival, acting partially redundantly with its paralog wun. [Date last reviewed: 2019-03-21]
FBgn0041092	tai	taiman	taiman (tai) encodes an ecdysone receptor co-activator related to mammalian steroid receptor coactivator (SRC) proteins. It contributes to border cell migration. [Date last reviewed: 2019-03-14]
FBgn0041094	scyl	scylla	NA
FBgn0041096	rols	rolling pebbles	rolling pebbles (rols) encodes a protein required for myoblast fusion in founder cells. it interacts with the membrane spanning Immunoglobulin superfamily protein encoded by kirre and with the product of Mhcl. [Date last reviewed: 2019-03-14]
FBgn0041100	park	parkin	parkin (park) encodes an E3 ubiquitin ligase with a key role in protein ubiquitination. It is involved in mitochondrion organization, oxidative stress and locomotion. [Date last reviewed: 2019-06-13]
FBgn0041111	lilli	lilliputian	NA
FBgn0041147	ida	imaginal discs arrested	imaginal discs arrested (ida) encodes a ubiquitin ligase that regulates the mitotic metaphase/anaphase transition. [Date last reviewed: 2019-07-11]
FBgn0041164	armi	armitage	armitage (armi) encodes a highly conserved cytosolic 5'-3' RNA helicase that is involved in biogenesis of PIWI-interacting RNAs (piRNAs), which suppress transposable elements in the fly germline. [Date last reviewed: 2019-03-21]
FBgn0041171	ago	archipelago	archipelago (ago) encodes a protein that is the founding member of the Ago/Fbxw7 family of tumor suppressor genes and the substrate adaptor component of the SCF-Ago ubiquitin ligase. The product of ago has various substrates including the bHLH transcription factors encoded by Myc, trh, and sima, and the G1 cell cycle kinase component encoded by CycE. The product of ago presents tissue specific roles in cell proliferation, survival, and hypoxia-induced gene expression. [Date last reviewed: 2019-03-07]
FBgn0041174	Vhl	von Hippel-Lindau	von Hippel-Lindau (Vhl) encodes a protein that regulates morphogenesis of trachea and follicular epithelium via its scaffolding functions. It promotes proteosomal degradation of the hypoxia inducible factor encoded by sima during normoxia. It also promotes vesicle transport via stabilization of microtubules and the endocytic factor encoded by awd. [Date last reviewed: 2019-03-21]
FBgn0041180	Tep4	Thioester-containing protein 4	Thioester-containing protein 4 (Tep4) is a member of the Thioester-containing proteins (TEP) family of genes. The product of Tep4 has endopeptidase inhibitor activity and participates in the cellular immune response to certain Gram-negative bacteria. [Date last reviewed: 2019-03-21]
FBgn0041182	Tep2	Thioester-containing protein 2	Thioester-containing protein 2 (Tep2) is a member of the Thioester-containing proteins (TEP) family of genes. The product of Tep2 has endopeptidase inhibitor activity and participates in the cellular immune response to certain Gram-negative bacteria. [Date last reviewed: 2019-03-21]
FBgn0041183	Tep1	Thioester-containing protein 1	NA
FBgn0041184	Socs36E	Suppressor of cytokine signaling at 36E	Suppressor of cytokine signaling at 36E (Socs36E) encodes a negative regulator of the JAK/STAT and EGFR pathways. It is a transcriptional target of the product of Stat92E that mediates lysosomal degradation following pathway stimulation and inhibits basal pathway activity. [Date last reviewed: 2019-03-21]
FBgn0041186	Slbp	Stem-loop binding protein	Stem-loop binding protein (Slbp) encodes a protein that plays an essential role in 3' end processing of histone pre-mRNAs into mature histone mRNAs by recruiting the product of snRNA:U7 to the pre-mRNA. [Date last reviewed: 2018-11-08]
FBgn0041188	Atx2	Ataxin-2	Ataxin-2 (Atx2) encodes the ortholog of human gene ATXN2, which is implicated in spinocerebellar ataxia 2. It contributes to eye development, circadian behaviour, and microRNA function. [Date last reviewed: 2019-03-07]
FBgn0041191	Rheb	Ras homolog enriched in brain	Ras homolog enriched in brain (Rheb) encodes a Ras homolog that is the target of the product of gig. It activates the protein kinase encoded by Tor, leading to enlarged cell size. [Date last reviewed: 2018-11-08]
FBgn0041205	key	kenny	kenny (key) encodes a scaffold protein that is a component of the IKK (IκB Kinase) complex, which participates in the activation of the transcription factor Rel in the Imd pathway. This pathway regulates the antibacterial response and other less characterized cellular processes. [Date last reviewed: 2019-03-14]
FBgn0041210	HDAC4	Histone deacetylase 4	Histone deacetylase 4 (HDAC4) encodes a Class IIa histone deacetylase that modulates gene expression by associating with transcriptional factors. It is regulated by nucleocytoplasmic shuttling and contributes to embryogenesis, muscle development, circadian function, energy balance and memory. [Date last reviewed: 2019-03-07]
FBgn0041225	Gr94a	Gustatory receptor 94a	NA
FBgn0041342	Pcyt1	Phosphocholine cytidylyltransferase 1	Phosphocholine cytidylyltransferase 1 (Pcyt1) encodes a choline-phosphate cytidylyltransferase involved in the endosomal traffic of several protein including the products of Egfr and N. [Date last reviewed: 2019-09-26]
FBgn0041582	tamo	tamo	tamo (tamo) encodes a protein with an essential function during oogenesis where it interacts with the product of dl and proteins that are part of the nuclear import machinery. [Date last reviewed: 2019-03-14]
FBgn0041585	Orai	Orai	olf186-F (olf186-F) encodes a plasma membrane localised protein that functions as a pore subunit of the store-operated calcium entry (SOCE) channel. [Date last reviewed: 2019-03-14]
FBgn0041588	eIF2D	eukaryotic translation initiation factor 2D	NA
FBgn0041604	dlp	dally-like	dally-like (dlp) encodes a glypican that regulates the signaling strength and range of the morphogens encoded by hh and wg. [Date last reviewed: 2019-09-12]
FBgn0041605	cpx	complexin	complexin (cpx) encodes a presynaptic cytosolic protein that regulates SNARE complex assembly and fuction. It has both positive and negative roles in synaptic transmission, serving as the synaptic vesicle fusion clamp and as an activator of evoked release. [Date last reviewed: 2019-03-07]
FBgn0041627	Ku80	Ku80	Ku80 (Ku80) encodes a protein that forms a Ku heterodimer with the product of Irbp, which binds to DNA double-strand break ends and is required for the non-homologous end joining pathway of DNA repair. [Date last reviewed: 2018-11-08]
FBgn0041629	Hexo2	Hexosaminidase 2	Hexosaminidase 2 (Hexo2) encodes a beta-N-acetylglucosaminidase involved in carbohydrate metabolism. [Date last reviewed: 2019-09-12]
FBgn0041630	Hexo1	Hexosaminidase 1	Hexosaminidase 1 (Hexo1) encodes a beta-N-acetylglucosaminidase involved in protein deglycosylation and rhodopsin biosynthesis. [Date last reviewed: 2019-09-12]
FBgn0041702	CG15107	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0041710	yellow-f	yellow-f	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0041712	yellow-d	yellow-d	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-10-13]
FBgn0041723	rho-5	rhomboid-5	NA
FBgn0041775	tral	trailer hitch	trailer hitch (tral) encodes a protein required for oocyte dorsoventral patterning via actin and microtubule cytoskeleton organization. [Date last reviewed: 2018-11-08]
FBgn0041781	SCAR	SCAR	SCAR (SCAR) encodes a primary regulator of the Arp2/3 complex, which promotes actin polymerization and influences cell shape and motility. It is involved in myoblast fusion, eye morphogenesis and axogenesis. [Date last reviewed: 2019-09-26]
FBgn0041789	Pax	Paxillin	Paxillin (Pax) encodes an adaptor protein that is generally associated with integrins. It is not required for most integrin-mediated adhesion or migration events, but is required for viability beyond pupal stages. It controls the size of some muscles by regulating the rate of cell fusion. [Date last reviewed: 2019-03-14]
FBgn0042083	Mccc2	Methylcrotonoyl-CoA carboxylase 2	NA
FBgn0042085	Bap170	Brahma associated protein 170kD	Brahma associated protein 170kD (Bap170) encodes a multidomain protein that forms a trimeric complex together with the products of e(y)3 and polybromo, characterizing the Brahma chromatin remodeling complex PBAP. [Date last reviewed: 2018-11-08]
FBgn0042092	Polr1F	RNA polymerase I subunit F	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0042094	Ak3	Adenylate kinase 3	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0042104	CG18747	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0042111	CG18766	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0042112	mRpL36	mitochondrial ribosomal protein L36	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0042132	CG18809	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0042133	CG18810	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0042134	Capr	Caprin	Caprin (Capr) encodes an RNA-binding translational regulator that is present in cytoplasmic RNA granules (neuronal granules and stress granules). It modulates diverse cellular processes including neuronal function, cell proliferation and differentiation through post-transcriptional regulation of target RNAs. [Date last reviewed: 2019-03-07]
FBgn0042135	Gdap2	Gdap2	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0042138	Apt1	Acyl-protein thioesterase 1	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0042175	CG18858	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0042177	Arts	Artemis	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0042178	Apl	Apollo	NA
FBgn0042180	CG18870	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0042185	MCU	Mitochondrial calcium uniporter	Mitochondrial calcium uniporter (MCU) encodes an inner mitochondrial membrane channel that transports calcium from the mitochondrial intermembrane space to the matrix. It is the main component of the mitochondrial calcium signaling pathway and functions in metabolism, cell death, and olfactory memory. [Date last reviewed: 2018-11-08]
FBgn0042205	CG18764	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0042206	GstD10	Glutathione S transferase D10	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0042213	CG18731	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-10-13]
FBgn0042627	FASN2	Fatty acid synthase 2	Fatty acid synthase 2 (FASN2) encodes an enzyme required for the synthesis of branched/methylated long chain fatty acids that are the precursors of methylated cuticular hydrocarbons. [Date last reviewed: 2019-03-07]
FBgn0042693	wrd	well-rounded	well-rounded (wrd) encodes one of the two regulatory B' subunits of the protein phosphatase PP2A. It influences metabolism and growth via negative regulation of the InR/TOR signalling network. [Date last reviewed: 2018-11-08]
FBgn0042712	HBS1	HBS1	HBS1 (HBS1) encodes an elongation factor class G protein that is implicated in messenger RNA quality control, by forming a protein complex with the product of pelo to promote decay of mRNAs with ribosomal stalls. [Date last reviewed: 2018-11-08]
FBgn0043001	Chrac-16	Chromatin accessibility complex 16kD protein	Chromatin accessibility complex 16kD protein (Chrac-16) encodes a subunit of the chromatin accessibility complex, which is an evolutionary conserved nucleosome sliding enzyme. [Date last reviewed: 2019-03-21]
FBgn0043010	Fsn	F-box synaptic protein	F-box synaptic protein (Fsn) encodes an F-box protein that forms a ubiquitin ligase complex with the E3 ligase and the Skp protein encoded by hiw and SkpA, respectively. Its key substrates are the products of wnd and Nmnat. [Date last reviewed: 2018-11-08]
FBgn0043012	AP-2sigma	Adaptor Protein complex 2, sigma subunit	Adaptor Protein complex 2, σ subunit (AP-2σ) encodes a component of the AP-2 adaptor complex, which recruits certain transmembrane proteins into clathrin-coated pits for endocytic internalization. [Date last reviewed: 2019-03-07]
FBgn0043025	Adgf-A2	Adenosine deaminase-related growth factor A2	Adenosine deaminase-related growth factor A2 (Adgf-A2) encodes a growth factor involved in spermatid development. [Date last reviewed: 2019-09-12]
FBgn0043070	MESK2	Misexpression suppressor of KSR 2	NA
FBgn0043362	bchs	blue cheese	blue cheese (bchs) is a neuronally expressed gene that encodes a member of the BEACH (Beige and Chediak-Higashi)-domain superfamily, whose members are involved in vesicle trafficking. It antagonizes the activity of the product of Rab11. It serves as a scaffold for autophagy proteins, and contributes to ref(2)P-mediated aggrephagy. It contributes to nervous system development, lysosome transport and sphingolipid metabolism. [Date last reviewed: 2018-11-08]
FBgn0043364	cbt	cabut	cabut (cbt) encodes a transcription factor that controls Dpp signaling and is involved in dorsal closure and wing disc morphogenesis. [Date last reviewed: 2019-03-07]
FBgn0043455	CG5986	NA	NA
FBgn0043456	Ndf	Nucleosome-destabilizing factor	Nucleosome-destabilizing factor (Ndf) encodes a putative H3K36me3 binding protein, which binds active gene bodies. [Date last reviewed: 2019-03-14]
FBgn0043457	CG5180	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0043458	CG12084	NA	NA
FBgn0043796	CG12219	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0043806	CG32032	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-10-13]
FBgn0043841	vir-1	virus-induced RNA 1	virus-induced RNA 1 (vir-1) is produced from a promoter that is induced by viral infection. It can be used as a marker of the induction of an antiviral response. Its expression is regulated by the Jak/STAT pathway. [Date last reviewed: 2019-03-21]
FBgn0043854	slam	slow as molasses	slow as molasses (slam) encodes a protein involved in cortical polarization and furrow invagination during cellularization, as well in germ cell migration during later embryogenesis. slam RNA co-localizes and forms a complex with its encoded protein, which is needed for full expression and subcellular localization. [Date last reviewed: 2018-11-08]
FBgn0043884	mask	multiple ankyrin repeats single KH domain	NA
FBgn0043900	pygo	pygopus	pygopus (pygo) encodes a key nuclear component of the Wnt signaling pathway. It facilitates the recruitment of the product of arm to Wnt-responsive genes by interacting with the transcription cofactor encoded by Chi. It also binds the product of lgs and the methylated tail of the product of His3. Together, they associate with the product of arm in a process that may function as a transition from gene silence to Wnt-induced transcription. [Date last reviewed: 2019-03-14]
FBgn0043903	dome	domeless	Domeless (dome) encodes the transmembrane receptor for signalling ligands (encoded by upd1, upd2 and upd3) in the cytokine family, which utilises the intracellular JAK/STAT pathway. The product of dome is involved in growth, stem cells, immune responses and development. [Date last reviewed: 2019-06-06]
FBgn0044020	Roc2	Regulator of cullins 2	Regulator of cullins 2 (Roc2) encodes a C2H2 type zinc finger protein that binds specifically to the product of Cul5 and recruits ubiquitin-charged E2 to the CRL5 E3 ubiquitin ligase complex, which functions during oogenesis. [Date last reviewed: 2019-03-14]
FBgn0044028	Notum	Notum	Notum (Notum) encodes an enzyme that cleaves glycophosphatidylinositol anchors. It acts via the product of dlp to influence the range and activity of secreted signaling proteins that interact with proteoglycans in the imaginal discs. [Date last reviewed: 2019-03-14]
FBgn0044030	mRpS14	mitochondrial ribosomal protein S14	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0044047	Ilp6	Insulin-like peptide 6	Insulin-like peptide 6 (Ilp6) encodes a protein that promotes growth during starvation. [Date last reviewed: 2019-06-27]
FBgn0044323	Cka	Connector of kinase to AP-1	NA
FBgn0044324	Chro	Chromator	Chromator (Chro) encodes a chromodomain protein that is required for proper microtubule spindle formation. It is important for normal cell cycle progression, functioning as a spatial regulator of cell cycle factors. [Date last reviewed: 2018-11-08]
FBgn0044452	Atg2	Autophagy-related 2	Autophagy-related 2 (Atg2) encodes a protein known to be required for autophagy. [Date last reviewed: 2019-03-07]
FBgn0044511	mRpS21	mitochondrial ribosomal protein S21	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0044823	Spec2	Spec2	NA
FBgn0044826	Pak3	Pak3	Pak3 (Pak3) encodes a Ser/Thr kinase implicated in myoblast fusion, synapse development, wound healing and border cell migration. It functions downstream of the small Rac GTPases to regulate actin cytoskeletal organization. [Date last reviewed: 2019-03-14]
FBgn0044871	Gos28	Golgi SNARE, 28 kDa	Golgi SNARE, 28 kDa (Gos28) encodes a protein involved in vesicular protein trafficking. It functions as a t-SNARE in medial- to trans-Golgi transport of rhodopsin during its biosynthesis. [Date last reviewed: 2018-11-08]
FBgn0045035	tefu	telomere fusion	NA
FBgn0045063	fdl	fused lobes	NA
FBgn0045064	bwa	brain washing	NA
FBgn0045073	Stim	Stromal interaction molecule	Stromal interaction molecule (Stim) encodes an endomasplic reticulum-membrane protein that is an essential component of the store-operated calcium entry mechanism, which in neurons regulates flight. [Date last reviewed: 2018-11-08]
FBgn0045469	Gr93c	Gustatory receptor 93c	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0045761	CHKov1	CHK domain ov1	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0045800	Uhg1	U snoRNA host gene 1	NA
FBgn0045823	vsg	visgun	visgun (vsg) encodes a protein involved in cell proliferation regulation, response to ethanol and long-term memory. [Date last reviewed: 2019-09-19]
FBgn0045842	yuri	yuri gagarin	yuri gagarin (yuri) encodes a protein involved in gravitaxis, ciliary basal body organization and sperm individualization. [Date last reviewed: 2019-09-19]
FBgn0045852	ham	hamlet	hamlet (ham) encodes a PRDM family transcription factor that regulates neuron fate selection in the peripheral nervous system and olfactory receptor neurons. It also controls intermediate precursor cell maturation in the type II neuroblast lineages of the larval brain. [Date last reviewed: 2019-03-07]
FBgn0045862	btz	barentsz	barentsz (btz) encodes a component of the exon junction complex that is recruited to spliced mRNAs to mark where introns have been removed. It is required for the posterior localization of osk mRNA. [Date last reviewed: 2019-03-07]
FBgn0045866	bai	baiser	NA
FBgn0046114	Gclm	Glutamate-cysteine ligase modifier subunit	Glutamate-cysteine ligase modifier subunit (Gclm) encodes a protein that regulates the ligase activity of the product of Gclc. It is involved in glutathione biosynthesis, arsenic detoxification and response to ethanol. [Date last reviewed: 2019-09-12]
FBgn0046214	vig2	vig2	vig2 (vig2) encodes a protein involved in heterochromatin organization, histone H3-K9 methylation and chromatin silencing regulation. [Date last reviewed: 2019-09-19]
FBgn0046222	Wdr33	WD repeat domain 33	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0046225	CG17230	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0046247	CG5938	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0046296	DEF8	differentially expressed in FDCP 8 homolog	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0046301	CG7148	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0046685	Wsck	Wsck	NA
FBgn0046687	Tre1	Trapped in endoderm 1	Trapped in endoderm 1 (Tre1) encodes a G protein-coupled receptor of the rhodopsin class. Its functions include primordial germ cell/pole cell migration and programmed cell death, central nervous system stem cell division orientation, and mating/courtship behavior. [Date last reviewed: 2018-11-08]
FBgn0046692	Stlk	Ste20-like kinase	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0046696	RNaseP:RNA	Ribonuclease P RNA	NA
FBgn0046704	Liprin-alpha	Liprin-alpha	Liprin-α (Liprin-α) encodes a scaffolding protein that interacts with the receptor phosphatase Lar. It is involved in synapse morphogenesis and axon guidance. [Date last reviewed: 2019-09-19]
FBgn0046706	Haspin	Haspin	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0046763	CG17278	NA	CG17278 encodes a secreted Kazal-type serine protease whose expression is induced by bacterial infection. RNAi results in lethality and wing adhesion defects. [Date last reviewed: 2019-03-07]
FBgn0046776	CR14033	NA	NA
FBgn0047038	ND-13B	NADH dehydrogenase (ubiquinone) 13 kDa B subunit	NA
FBgn0047114	CG31142	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0047135	CG32276	NA	NA
FBgn0047178	CG32147	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0047205	lncRNA:CR32385	long non-coding RNA:CR32385	NA
FBgn0050000	GstT1	Glutathione S transferase T1	Glutathione S transferase T1 (GstT1) encodes an enzyme involved in glutathione metabolic processes. [Date last reviewed: 2019-06-27]
FBgn0050001	CG30001	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0050005	GstT2	Glutathione S transferase T2	Glutathione S transferase T2 (GstT2) encodes an enzyme involved in glutathione metabolic processes. [Date last reviewed: 2019-06-27]
FBgn0050011	gem	gemini	NA
FBgn0050015	CG30015	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0050020	CG30020	NA	NA
FBgn0050022	CG30022	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0050035	Tret1-1	Trehalose transporter 1-1	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0050044	s-cup	stanley-cup	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0050046	CG30046	NA	NA
FBgn0050051	Tmem18	Transmembrane protein 18	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0050055	lncRNA:CR30055	long non-coding RNA:CR30055	NA
FBgn0050069	CG30069	NA	CG30069 encodes a large protein conserved in other insects with up to 80 copies of a tandem array of a 29 amino acid repeat. Ubiquitous CG30069 RNAi causes lethality and wing-specific RNAi causes wing adhesion defects. [Date last reviewed: 2019-03-07]
FBgn0050077	Blos1	Biogenesis of lysosome-related organelles complex 1, subunit 1	Biogenesis of lysosome-related organelles complex 1, subunit 1 (Blos1) encodes a subunit of the octameric complex BLOC-1. BLOC-1 is a cytosolic factor involved in membrane traffic that controls eye color, synaptic morphology, homeostatic synaptic plasticity, and synaptic vesicle recycling. [Date last reviewed: 2019-03-07]
FBgn0050085	Rif1	Rap1 interacting factor 1	Rap1 interacting factor 1 (Rif1) encodes a protein that binds protein phosphatase PP1 and is required for temporal regulation of replication initiation. [Date last reviewed: 2019-03-14]
FBgn0050089	CG30089	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0050090	CG30090	NA	NA
FBgn0050094	CG30094	NA	NA
FBgn0050105	CG30105	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0050109	CG30109	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0050115	GEFmeso	Guanine nucleotide exchange factor in mesoderm	Guanine nucleotide exchange factor in mesoderm (GEFmeso) encodes a protein that regulates the products of Rala and Cdc42. It is involved in leg morphogenesis and wing vein specification. [Date last reviewed: 2019-07-11]
FBgn0050122	CG30122	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0050147	Hil	Hillarin	Hillarin (Hil) encodes a W180-domain protein that affects cytokinesis through interactions with the Septin family member encoded by pnut in the developing nervous system. [Date last reviewed: 2019-03-07]
FBgn0050148	CG30148	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0050156	CG30156	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0050157	CG30157	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0050159	CG30159	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0050169	Brca2	BRCA2, DNA repair associated	BRCA2, DNA repair associated (Brca2) encodes the ortholog of the human BRCA2 gene, which acts as a tumor suppressor. It is involved in double-strand break repair via homologous recombination. During meiosis in females it is involved in DNA repair and in the activation of a meiotic checkpoint. It co-immunoprecipitates with the checkpoint protein encoded by Rad9. [Date last reviewed: 2018-11-08]
FBgn0050183	CG30183	NA	NA
FBgn0050184	CG30184	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0050185	AIMP3	aaRS-interacting multifunctional protein 3	aaRS-interacting multifunctional protein 3 (AIMP3) is predicted to encode one of 3 non-enzymatic factors that combine with eight aminoacyl-tRNA synthetases to form a 'multi-synthetase complex' (MSC). The functional significance of the MSC is unclear, but the non-enzymatic factors are thought to be responsive to diverse signal transduction pathways. [Date last reviewed: 2019-03-07]
FBgn0050187	CG30187	NA	NA
FBgn0050269	CG30269	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0050273	CG30273	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0050291	CG30291	NA	NA
FBgn0050295	Ipk1	Ipk1	NA
FBgn0050323	CG30323	NA	NA
FBgn0050338	CG30338	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0050339	CG30339	NA	NA
FBgn0050340	CG30340	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0050342	Prp38	pre-mRNA processing factor 38	NA
FBgn0050344	CG30344	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0050345	CG30345	NA	NA
FBgn0050349	CG30349	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0050357	CG30357	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-10-13]
FBgn0050359	Mal-A5	Maltase A5	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0050372	Asap	ArfGAP with SH3 domain, ankyrin repeat and PH domain	ArfGAP with SH3 domain, ankyrin repeat and PH domain (Asap) encodes a GTPase activating proteins for Arf family GTPases. Arf proteins regulate actin dynamics, cell shape, and cell positioning within epithelia such as the eye. [Date last reviewed: 2019-03-07]
FBgn0050373	CG30373	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-10-13]
FBgn0050381	PIG-X	Phosphatidylinositol glycan anchor biosynthesis class X	NA
FBgn0050383	CG30383	NA	NA
FBgn0050389	CG30389	NA	NA
FBgn0050390	Sgf29	SAGA-associated factor 29kDa	SAGA-associated factor 29kDa (Sgf29) encodes a encodes subunit of some chromatin modifying complexes. [Date last reviewed: 2019-08-01]
FBgn0050392	CG30392	NA	NA
FBgn0050394	CG30394	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0050403	CG30403	NA	NA
FBgn0050404	Tango11	Transport and Golgi organization 11	NA
FBgn0050410	Rpi	Ribose-5-phosphate isomerase	NA
FBgn0050414	CG30414	NA	NA
FBgn0050421	Usp15-31	Ubiquitin specific protease 15/31	Ubiquitin specific protease 15/31 (Usp15-31) encodes a ubiquitin C-terminal hydrolase that is involved in the positive regulation of the apoptosome components encoded by Dark and Dronc. [Date last reviewed: 2018-11-15]
FBgn0050423	CG30423	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0050428	CG30428	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0050438	Ugt50B3	UDP-glycosyltransferase family 50 member B3	NA
FBgn0050440	CG30440	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0050443	Opbp	Optix-binding protein	Optix-binding protein (Opbp) encodes a Zn finger protein that can bind to the Six-family transcription factor encoded by Optix. [Date last reviewed: 2019-03-14]
FBgn0050460	CG30460	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0050463	Pgant9	Polypeptide N-Acetylgalactosaminyltransferase 9	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0050466	CG30466	NA	NA
FBgn0050467	CG30467	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0050476	ave	aveugle	aveugle (ave) encodes an adaptor protein that binds to the scaffolding protein encoded by cnk and promotes the activation of the product of Raf by recruiting the product of ksr. [Date last reviewed: 2019-03-07]
FBgn0050491	CG30491	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0050493	Coq9	Coenzyme Q9	NA
FBgn0050496	CG30496	NA	NA
FBgn0050499	Rpe	Ribulose-5-phosphate-3-epimerase	NA
FBgn0050502	fa2h	fatty acid 2-hydroylase	NA
FBgn0051005	qless	qless	qless (qless) encodes a protein involved in the synthesis of the isoprenoid side chain of Coenzyme Q, a lipid component of the mitochondrial electron transport chain. [Date last reviewed: 2018-11-15]
FBgn0051029	CG31029	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0051032	CR31032	NA	NA
FBgn0051038	CG31038	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0051040	Cog7	Component of oligomeric golgi complex 7	NA
FBgn0051044	lncRNA:CR31044	long non-coding RNA::CR31044	NA
FBgn0051064	CG31064	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0051068	CG31068	NA	NA
FBgn0051072	Lerp	lysosomal enzyme receptor protein	lysosomal enzyme receptor protein (Lerp) encodes a protein involved in lysosome function and autophagy. [Date last reviewed: 2018-11-15]
FBgn0051075	CG31075	NA	NA
FBgn0051092	LpR2	Lipophorin receptor 2	Lipophorin receptor 2 (LpR2) encodes a transmembrane receptor. A subset of LpR2-encoded isoforms are involved in the cellular uptake of neutral lipids from the circulating protein encoded by apolpp. [Date last reviewed: 2019-03-14]
FBgn0051098	CG31098	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-10-13]
FBgn0051108	TTLL5	Tubulin tyrosine ligase-like 5	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0051109	CG31109	NA	NA
FBgn0051111	CG31111	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0051116	ClC-a	Chloride channel-a	Chloride channel-a (ClC-a) encodes a plasma membrane chloride channel expressed in the stellate cells of Malpighian tubules. It is involved in transepithelial transport of ions and water. [Date last reviewed: 2018-11-15]
FBgn0051118	RabX4	RabX4	NA
FBgn0051122	CG31122	NA	NA
FBgn0051126	CG31126	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0051133	Slimp	Seryl-tRNA synthetase-like insect mitochondrial protein	Seryl-tRNA synthetase-like insect mitochondrial protein (Slimp) encodes an essential mitochondrial protein with a sharp expression profile during the G2 phase of the cell cycle. [Date last reviewed: 2019-03-14]
FBgn0051140	CG31140	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0051151	wge	winged eye	winged eye (wge) encodes a protein that localizes to the histone locus body and regulates histone expression to ensure genomic stability. wge overexpression produces eye to wing transformation. [Date last reviewed: 2019-03-21]
FBgn0051155	Polr2G	RNA polymerase II subunit G	NA
FBgn0051156	CG31156	NA	NA
FBgn0051158	Efa6	Exchange factor for Arf 6	Exchange factor for Arf 6 (Efa6) encodes a Guanine Nucleotide Exchange Factor (GEF) that sustains activation of Arf family GTPases. They are active in dynamic actin rearrangement during cell shapes changes as well as cell patterning within epithelia. [Date last reviewed: 2019-03-07]
FBgn0051159	mRRF2	mitochondrial ribosome recycling factor 2	mitochondrial ribosome recycling factor 2 (mRRF2) encodes a mitochondrial elongation factor that catalyzes the translocation of the mRNAs and tRNAs along the ribosomes via GTP hydrolysis. [Date last reviewed: 2019-03-14]
FBgn0051184	LSm3	Like Sm 3	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0051195	CG31195	NA	NA
FBgn0051211	CG31211	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0051216	Naam	Nicotinamide amidase	Nicotinamide amidase (Naam) encodes a nicotinamidase involved in lifespan determination, neuron apoptosis regulation and response to oxidative stress. [Date last reviewed: 2019-09-26]
FBgn0051217	modSP	modular serine protease	modular serine protease (modSP) encodes a protein that functions downstream of microbial sensing receptors encoded by PGRP-SA and GNBP3 in the extracellular proteolytic cascade leading to Toll pathway activation during the immune response. It initiates the proteolytic cascade leading to the cleavage of the Toll ligand encoded by spz. [Date last reviewed: 2019-03-14]
FBgn0051219	CG31219	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0051223	CG31223	NA	NA
FBgn0051224	CG31224	NA	NA
FBgn0051229	CG31229	NA	NA
FBgn0051249	CG31249	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0051251	CG31251	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0051278	CG31278	NA	NA
FBgn0051301	CG31301	NA	NA
FBgn0051320	HEATR2	HEAT repeat containing 2	NA
FBgn0051324	CG31324	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0051337	CG31337	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0051342	CG31342	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0051344	CG31344	NA	NA
FBgn0051352	Unc-115a	Uncoordinated 115a	Uncoordinated 115a (Unc-115a) encodes a protein involved in axon pathfinding in the visual system and the CNS. [Date last reviewed: 2019-03-21]
FBgn0051357	Kaz	Katazuke	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0051360	CG31360	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0051361	dpr17	defective proboscis extension response 17	NA
FBgn0051363	Jupiter	Jupiter	NA
FBgn0051365	CG31365	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0051368	CG31368	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0051370	CG31370	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0051388	CG31388	NA	NA
FBgn0051390	MED7	Mediator complex subunit 7	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0051431	CG31431	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0051436	CG31436	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0051441	CG31441	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0051445	CG31445	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0051450	mRpS18A	mitochondrial ribosomal protein S18A	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0051451	lncRNA:CR31451	long non-coding RNA::CR31451	NA
FBgn0051453	pch2	pachytene checkpoint 2	pachytene checkpoint 2 (pch2) encodes a protein involved in a checkpoint pathway that monitors the synaptonemal complex assembly and recombination during female meiosis. [Date last reviewed: 2019-03-14]
FBgn0051457	CG31457	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0051460	CG31460	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0051472	sgll	sugarlethal	sugarlethal (sgll) encodes pyridoxine 5'-phosphate oxidase (PNPO). PNPO converts pyridoxine to its active form pyridoxal 5'-phosphate (PLP). PLP is a co-factor required for more than 100 enzymes that function in amino acid metabolism, gluconeogenesis and neurotransmitter synthesis. [Date last reviewed: 2019-03-14]
FBgn0051477	ATPsynepsilonL	ATP synthase, epsilon subunit-like	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0051495	CG31495	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0051510	CG31510	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-10-13]
FBgn0051514	asRNA:CR31514	antisense RNA:CR31514	NA
FBgn0051522	CG31522	NA	NA
FBgn0051523	CG31523	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0051546	CG31546	NA	NA
FBgn0051548	CG31548	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0051549	CG31549	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0051550	CG31550	NA	NA
FBgn0051601	CG31601	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0051612	CG31612	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0051614	His-Psi:CR31614	His-Psi:CR31614	NA
FBgn0051619	nolo	no long nerve cord	no long nerve cord (nolo) encodes a protein involved in ventral cord development. [Date last reviewed: 2019-09-12]
FBgn0051633	CG31633	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0051635	CG31635	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0051637	CG31637	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0051638	CG31638	NA	CG31638 is expressed in the mesoderm and is regulated by the RNA-binding protein encoded by how. [Date last reviewed: 2019-03-07]
FBgn0051642	CG31642	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0051648	CG31648	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0051658	Nnf1b	Nnf1b	Nnf1b (Nnf1b) encodes a component of the Mis12 complex, which is an essential constituent of the kinetochore. [Date last reviewed: 2019-03-14]
FBgn0051673	CG31673	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0051674	CG31674	NA	NA
FBgn0051678	CG31678	NA	NA
FBgn0051687	CG31687	NA	NA
FBgn0051694	Ifrd1	Interferon-related developmental regulator 1	NA
FBgn0051710	CG31710	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0051712	CG31712	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0051715	CG31715	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0051716	Cnot4	CCR4-NOT transcription complex subunit 4	CCR4-NOT transcription complex subunit 4 (Cnot4) encodes a positive regulator of the Jak/Stat pathway which acts by stabilizing the DNA binding of the product of Stat92E. [Date last reviewed: 2019-03-07]
FBgn0051717	CG31717	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0051720	mthl15	methuselah-like 15	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0051729	CG31729	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0051739	AspRS-m	Aspartyl-tRNA synthetase, mitochondrial	Aspartyl-tRNA synthetase, mitochondrial (AspRS-m) encodes a protein predicted to function within mitochondria to catalyze the ligation of aspartate to its cognate tRNA to form aspartyl-tRNA. [Date last reviewed: 2019-03-07]
FBgn0051755	SoYb	Sister of Yb	Sister of Yb (SoYb) encodes a putative RNA helicase in the TDRD12 family. It has an essential role in primary piRNA biogenesis in ovarian somatic cells and is predicted to also have a role in germline piRNA biogenesis. [Date last reviewed: 2019-03-14]
FBgn0051759	CG31759	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0051769	CG31769	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0051777	CG31777	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0051793	CG31793	NA	NA
FBgn0051800	CG31800	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0051815	CG31815	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0051849	Mgat3	beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase	NA
FBgn0051852	Tap42	Two A-associated protein of 42kDa	Two A-associated protein of 42kDa (Tap42) encodes a phosphatase inhibitor involved in wing disc morphogenesis and the organization of the mitotic spindle. [Date last reviewed: 2019-09-19]
FBgn0051855	CG31855	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0051875	CG31875	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0051898	CG31898	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0051908	CG31908	NA	NA
FBgn0051915	CG31915	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0051922	CG31922	NA	NA
FBgn0051935	Rab3GAP1	RAB3 GTPase activating protein catalytic subunit 1	NA
FBgn0051950	Sbat	Sabbat	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0051955	CG31955	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0051957	CG31957	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0051961	TBCC	Tubulin-binding cofactor C	NA
FBgn0051973	Cda5	Chitin deacetylase-like 5	NA
FBgn0051974	CG31974	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0051989	Cap-D3	Chromosome associated protein D3	NA
FBgn0051992	gw	gawky	NA
FBgn0051997	CG31997	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0051998	CG31998	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0051999	CG31999	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0052000	anne	anne boleyn	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0052016	4E-T	eIF4E-Transporter	eIF4E-Transporter (4E-T) encodes a large protein that interacts with regulators of translation and mRNA stability, including CNOT1 and LSM14 as well as the products of me31B and eIF4E1. Levels of the 4E-T product are particularly high in germ cells and early development when translational control predominates in gene regulation. [Date last reviewed: 2019-03-07]
FBgn0052017	CG32017	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0052022	CG32022	NA	NA
FBgn0052026	CG32026	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0052027	lncRNA:CR32027	long non-coding RNA:CR32027	NA
FBgn0052037	CG32037	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0052039	CG32039	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0052056	scramb1	scramblase 1	scramblase 1 (scramb1) encodes a protein that, together with the product of scramb2, has a modulatory function in the process of neurotransmission. They have a significant role in scrambling of phospholipids across the plasma membrane during apoptosis. [Date last reviewed: 2019-03-14]
FBgn0052062	Rbfox1	RNA-binding Fox protein 1	RNA-binding Fox protein 1 (Rbfox1) encodes RNA-binding proteins that bind to (U)GCAUG elements. Nuclear isoforms of the product of Rbfox1 regulate tissue specific alternative splicing, while cytoplasmic isoforms regulate mRNA translation. It functions in a number of processes, including germline cyst development. [Date last reviewed: 2019-03-14]
FBgn0052066	CG32066	NA	NA
FBgn0052068	Adi1	Acireductone dioxygenase 1	Acireductone dioxygenase 1 (Adi1) encodes an enzyme in the methionine salvage pathway (MTA cycle) that is required for fecundity. [Date last reviewed: 2019-03-07]
FBgn0052069	CG32069	NA	NA
FBgn0052075	CG32075	NA	NA
FBgn0052076	Alg10	ALG10 alpha-1,2-glucosyltransferase	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0052088	sunn	sisters unbound	sisters unbound (sunn) encodes a chromosome protein involved in the meiotic sister chromatid cohesion pathway. It is required for sister centromere cohesion in both male and female meiosis and for maintenance of synaptonemal complexes and normal levels of homolog crossing-over in female meiosis. [Date last reviewed: 2019-03-14]
FBgn0052091	CG32091	NA	NA
FBgn0052095	CG32095	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0052099	CG32099	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0052100	CG32100	NA	NA
FBgn0052103	SCaMC	Short Calcium-binding Mitochondrial Carrier	Short Calcium-binding Mitochondrial Carrier (SCaMC) encodes a mitochondrial carrier family protein with calcium-binding motifs. SCaMC transcripts are strongly detected in the corpora allata, suggesting its potential role in juvenile hormone biosynthesis. [Date last reviewed: 2019-09-26]
FBgn0052104	CG32104	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0052109	CG32109	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0052112	CG32112	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0052113	Vps13D	Vacuolar protein sorting 13D	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0052115	CG32115	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-10-13]
FBgn0052133	Ptip	PAX transcription activation domain interacting protein	PAX transcription activation domain interacting protein (Ptip) encodes a component of a Histone H3K4 methyltransferase complex that contributes to Trithorax-mediated epigenetic imprinting during development. [Date last reviewed: 2018-11-15]
FBgn0052163	CG32163	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-10-13]
FBgn0052170	CG32170	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0052176	CG32176	NA	NA
FBgn0052177	Ndfip	Nedd4 family interacting protein	Nedd4 family interacting protein (Ndfip) encodes a protein that interacts with the ubiquitin ligases encoded by Nedd4 and Su(dx) and regulates Notch signaling. [Date last reviewed: 2019-03-14]
FBgn0052179	Krn	Keren	Keren (Krn) encodes an ligand for the receptor encoded by Egfr that is processed by the products of S and rho. It shows a redundant role with the products of spi in very few tissues. [Date last reviewed: 2019-03-14]
FBgn0052181	CG32181	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-10-13]
FBgn0052182	CG32182	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-10-13]
FBgn0052190	NUCB1	NUCB1	NUCB1 (NUCB1) encodes a protein involved in the defense response to Gram-negative bacteria. [Date last reviewed: 2019-09-26]
FBgn0052195	CG32195	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0052202	CG32202	NA	NA
FBgn0052206	CG32206	NA	NA
FBgn0052218	lncRNA:CR32218	long non-coding RNA:CR32218	NA
FBgn0052221	CG32221	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0052226	Pex23	Peroxin 23	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0052230	ND-MLRQ	NADH dehydrogenase (ubiquinone) MLRQ subunit	NA
FBgn0052243	CG32243	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-10-13]
FBgn0052250	PMP34	Peroxisomal Membrane Protein 34	NA
FBgn0052251	Claspin	Claspin	Claspin (Claspin) encodes a nuclear protein that is involved in the ATR-Chk1 checkpoint pathway. It is required for the cell cycle checkpoint induced at midblastula transition. [Date last reviewed: 2019-03-07]
FBgn0052262	CG32262	NA	NA
FBgn0052264	CG32264	NA	NA
FBgn0052267	CG32267	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0052278	CG32278	NA	NA
FBgn0052280	CG32280	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0052281	CG32281	NA	NA
FBgn0052296	Mrtf	Myocardin-related transcription factor	Myocardin-related transcription factor (Mrtf) encodes a protein that binds to the product of bs, and likely other transcription factors, to enhance downstream gene activation. The activity of the product of Mrtf is regulated by free actin levels. It contributes to tracheal branching, border cell migration, and other cell stretching and invasive migration processes during development. [Date last reviewed: 2019-03-14]
FBgn0052311	zormin	zormin	zormin (zormin) encodes a protein found in the Z-disc and the M-line of muscles. It probably has a structural function. [Date last reviewed: 2019-03-21]
FBgn0052343	Atac3	Ada2a-containing complex component 3	Ada2a-containing complex component 3 (Atac3) encodes a protein involved in chromatin remodeling and histone acetylation. [Date last reviewed: 2019-06-27]
FBgn0052344	CG32344	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0052350	Vps11	Vacuolar protein sorting 11	Vacuolar protein sorting 11 (Vps11) encodes a Class C Vps core subunit of HOPS, a heterohexameric tethering complex that consists of the products of car, dor, lt, Vps11, Vps16A and Vps39. HOPS tethers autophagosomes or late endosomes with lysosomes to facilitate fusion. The product of Vps11 roles include autophagosome-lysosome fusion, late endosome-lysosome fusion and biosynthetic trafficking to lysosomes. [Date last reviewed: 2019-03-21]
FBgn0052364	tut	tumorous testis	tumorous testis (tut) encodes an RNA-binding protein that forms a complex with the products of bam and bgcn. It is required for the restrained mitotic amplification of germ cells during spermatogenesis. [Date last reviewed: 2019-03-14]
FBgn0052368	CG32368	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0052369	CG32369	NA	NA
FBgn0052380	SMSr	SMSr	NA
FBgn0052407	CG32407	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0052409	CG32409	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0052412	QC	Glutaminyl cyclase	Glutaminyl cyclase (QC) encodes a glutaminyl-peptide cyclotransferase involved in peptidyl-pyroglutamic acid biosynthesis. [Date last reviewed: 2019-09-12]
FBgn0052418	vito	viriato	viriato (vito) is a Myc-target gene encoding a nucleolar protein that is required for proper cell and tissue growth. In the developing eye, it is required for correct signal transduction in the cells receiving the product of dpp. [Date last reviewed: 2019-03-21]
FBgn0052423	shep	alan shepard	alan shepard (shep) encodes an evolutionarily conserved RNA/DNA binding protein that regulates alternative splicing and gypsy insulator activities. It regulates neural development during the embryonic and larval stages, and neuronal remodeling during metamorphosis. [Date last reviewed: 2019-03-14]
FBgn0052425	CG32425	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0052428	CG32428	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0052436	CG32436	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0052438	SMC5	Structural maintenance of chromosomes 5	Structural maintenance of chromosomes 5 (SMC5) encodes a component of the SMC5/6 protein complex that is critical to genome stability and required for homologous DNA recombination-based processes. [Date last reviewed: 2018-11-15]
FBgn0052441	EMC10	ER membrane protein complex subunit 10	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0052446	Atox1	Antioxidant 1 copper chaperone	Antioxidant 1 copper chaperone (Atox1) null mutants are unable to develop on low-copper food. Furthermore, the intestinal copper importer encoded by Ctr1B, which is regulated by copper demand, fails to be induced upon copper starvation in Atox1 mutant larvae, while intestinal metallothionein is upregulated. This suggests intestinal copper accumulation, combined with insufficient delivery to the rest of the body. [Date last reviewed: 2019-03-07]
FBgn0052448	CG32448	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0052451	SPoCk	Secretory Pathway Calcium atpase	Secretory Pathway Calcium atpase (SPoCk) encodes a transporting ATPase with roles in the maintenance of cellular Ca2+ homeostasis. [Date last reviewed: 2019-09-12]
FBgn0052452	CG32452	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0052473	CG32473	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0052479	Usp10	Ubiquitin specific protease 10	NA
FBgn0052483	CG32483	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0052484	Sk2	Sphingosine kinase 2	Sphingosine kinase 2 (Sk2) encodes a D-erythro-sphingosine kinase that contributes to sphingolipid metabolism, flight performance and ovulation. [Date last reviewed: 2019-09-12]
FBgn0052485	CG32485	NA	NA
FBgn0052512	CG32512	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0052521	CG32521	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0052528	parvin	parvin	parvin (parvin) encodes a Calponin-homology protein that, together with the products of Ilk and stck, reinforces integrin-matrix adhesion at muscle attachment sites in the developing embryo. The product of parvin contributes to cell adhesion and actin cytoskeleton organisation in muscles, wing and eye epithelial cells. [Date last reviewed: 2019-03-14]
FBgn0052529	Hers	Histone gene-specific Epigenetic Repressor in late S phase	NA
FBgn0052532	CG32532	NA	NA
FBgn0052533	CG32533	NA	NA
FBgn0052537	CG32537	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-10-13]
FBgn0052549	Nt5b	5' nucleotidase B	NA
FBgn0052554	CG32554	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0052557	Mco4	Multicopper oxidase 4	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0052572	CG32572	NA	NA
FBgn0052576	CG32576	NA	NA
FBgn0052579	CG32579	NA	NA
FBgn0052580	Muc14A	Mucin 14A	NA
FBgn0052582	lncRNA:CR32582	long non-coding RNA:CR32582	NA
FBgn0052590	CG32590	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0052594	be	ben	ben (be) encodes a protein involved in neuromuscular synaptic transmission and long-term memory formation. [Date last reviewed: 2019-09-19]
FBgn0052625	CG32625	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0052626	AMPdeam	AMP deaminase	NA
FBgn0052638	CG32638	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0052649	Coq8	Coenzyme Q8	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0052650	CG32650	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0052654	Sec16	Secretory 16	Secretory 16 (Sec16) encodes a protein involved in the organization of endoplasmic reticulum exit sites. It contributes to stress response to amino-acid starvation, during which it mediates the formation of both Sec bodies and stress granules. [Date last reviewed: 2018-11-15]
FBgn0052666	Drak	Death-associated protein kinase related	Death-associated protein kinase related (Drak) encodes a protein serine/threonine kinase belonging to the Death-associated protein kinase family. It promotes phosphorylation of the product of sqh at sites known to stimulate actomyosin contractility. Its main characterized function is to shape epithelial tissues during development. [Date last reviewed: 2019-03-07]
FBgn0052672	Atg8a	Autophagy-related 8a	Autophagy-related 8a (Atg8a) encodes a ubiquitin-like protein that is conjugated to phosphatidylethanolamine, and this lipid modification anchors it into the membrane of forming and completed autophagosomes. Atg8a product has roles in autophagosome formation, maintaining neuromuscular function and normal lifespan. [Date last reviewed: 2019-03-07]
FBgn0052675	Tango5	Transport and Golgi organization 5	NA
FBgn0052676	stx	stuxnet	stuxnet (stx) encodes a protein that controls the homeostasis of the product of Pc via proteasomal degradation through an ubiquitin-independent pathway. [Date last reviewed: 2018-11-15]
FBgn0052677	X11Lbeta	X11Lbeta	NA
FBgn0052681	CG32681	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-10-13]
FBgn0052685	ZAP3	ZAP3	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0052687	CG32687	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0052699	LPCAT	Lysophosphatidylcholine acyltransferase	Lysophosphatidylcholine acyltransferase (LPCAT) encodes an enzyme involved in the synthesis of the major membrane lipid phosphatidylcholine. Combined with the activity of the phospholipase encoded by Pla2, it allows exchange of fatty acids on the sn-2 position, which is the major pathway to introduce polyunsaturated fatty acids into membrane phospholipids. [Date last reviewed: 2018-11-15]
FBgn0052702	Cubn	Cubilin	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0052707	APC4	Anaphase Promoting Complex subunit 4	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0052708	CG32708	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0052719	CG32719	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-10-13]
FBgn0052732	Setd3	SET domain containing 3	NA
FBgn0052756	CG32756	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0052758	Snx27	Sorting nexin 27	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0052767	CG32767	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0052772	CG32772	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0052791	DIP-alpha	Dpr-interacting protein alpha	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0052803	CG32803	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0052813	CG32813	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0052823	Sdic3	Sperm-specific dynein intermediate chain 3	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0052850	Rnf11	Ring finger protein 11	NA
FBgn0052856	CG32856	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0052865	lncRNA:alphagamma-element:CR32865	alphagamma-element:CR32865	NA
FBgn0052982	CG32982	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-10-13]
FBgn0052984	CG32984	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0052985	CG32985	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0053002	mRpL27	mitochondrial ribosomal protein L27	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0053051	Polr3G	RNA polymerase III subunit G	NA
FBgn0053052	Gorab	Golgin, RAB6 interacting	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0053054	CG33054	NA	NA
FBgn0053056	CG33056	NA	NA
FBgn0053057	CG33057	NA	NA
FBgn0053062	CG33062	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0053080	CG33080	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0053087	LRP1	LDL receptor protein 1	NA
FBgn0053094	Synd	Syndapin	NA
FBgn0053095	CG33095	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0053096	CG33096	NA	NA
FBgn0053100	eIF4EHP	eukaryotic translation initiation factor 4E homologous protein	eukaryotic translation initiation factor 4E homologous protein (eIF4EHP) encodes a protein that binds the 7-methyl-guanosine cap structure of mRNA and functions as a negative regulator of translation. The product of eIF4EHP contributes to embryonic patterning by negatively regulating translation of the products of cad and hb, and is also implicated in regulating ecdysone biosynthesis. [Date last reviewed: 2019-03-07]
FBgn0053107	CG33107	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-10-13]
FBgn0053111	CG33111	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-10-13]
FBgn0053113	Rtnl1	Reticulon-like1	Reticulon-like1 (Rtnl1) encodes a reticulon family member, with predicted intramembrane hairpin domains that can insert into the cytosolic face of the endoplasmic reticulum (ER), thereby curving it and promoting ER tubule formation. It is enriched on tubular ER, including axons and egg chamber fusomes. [Date last reviewed: 2018-11-15]
FBgn0053116	CG33116	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0053120	CG33120	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0053124	CG33124	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0053129	CG33129	NA	NA
FBgn0053138	AGBE	1,4-Alpha-Glucan Branching Enzyme	1,4-Alpha-Glucan Branching Enzyme (AGBE) encodes a protein that is inferred to be a hydrolase involved in glycogen synthesis and hypoxia, based on the function of its orthologs. It contributes to the determination of lifespan. [Date last reviewed: 2019-03-07]
FBgn0053144	CG33144	NA	NA
FBgn0053145	GalT1	beta1,3-galactosyltransferase 1	β1,3-galactosyltransferase 1 (GalT1) encodes an enzyme involved in protein N-linked glycosylation. [Date last reviewed: 2019-09-12]
FBgn0053156	CG33156	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0053158	CG33158	NA	NA
FBgn0053169	CG33169	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0053170	CG33170	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0053172	CG33172	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0053180	Ranbp16	Ranbp16	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0053181	CG33181	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0053182	Kdm4B	Lysine demethylase 4B	Lysine (K)-specific demethylase 4B (Kdm4B) encodes a histone demethylase that removes methyl groups from histone 3 lysines 9 and 36. It participates in DNA repair and transcription regulation. [Date last reviewed: 2019-09-26]
FBgn0053193	sav	salvador	salvador (sav) encodes a scaffold protein involved in the Hippo signalling pathway. It promotes membrane recruitment of the kinase encoded by hpo and its assembly with the product of wts. [Date last reviewed: 2018-11-15]
FBgn0053196	dpy	dumpy	dumpy (dpy) encodes an extracellular protein involved in epidermal-cuticle attachment, aposition of wing surfaces and trachea development. [Date last reviewed: 2019-09-26]
FBgn0053198	pen-2	presenilin enhancer	NA
FBgn0053207	pxb	pxb	pxb (pxb) encodes a protein involved in response to ethanol, long-term memory and regulation of hemocyte proliferation. [Date last reviewed: 2019-09-26]
FBgn0053208	Mical	Molecule interacting with CasL	Molecule interacting with CasL (Mical) encodes a multi-domain flavoprotein monooxygenase (Redox) enzyme. It is activated by actin filaments, and then oxidizes actin on methionines 44 and 47, disassembling the actin filaments and inhibiting actin polymerization. This regulates cell morphology in the nervous system and muscle, working with the the receptor encoded by PlexA and cofilin, encoded by tsr. [Date last reviewed: 2019-03-14]
FBgn0053213	CG33213	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0053217	CG33217	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-10-13]
FBgn0053225	CG33225	NA	NA
FBgn0053229	CG33229	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0053230	CG33230	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0053276	Urm1	Ubiquitin-related modifier 1	NA
FBgn0053294	CR33294	NA	NA
FBgn0053303	CG33303	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0053307	CG33307	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0053329	Sp212	Serine-peptidase 212	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0053460	CG33460	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0053461	CG33461	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0053465	CG33465	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0053494	CG33494	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0053503	Cyp12d1-d	Cytochrome P450 12d1 distal	Cyp12d1-d (Cyp12d1-d) encodes a protein involved in the response to the insecticide dichlorodiphenyltrichloroethane (DDT). [Date last reviewed: 2019-09-12]
FBgn0053505	U3-55K	U3 small nuclear riboprotein factor 55K	NA
FBgn0053506	CG33506	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0053508	ppk13	pickpocket 13	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0053509	CG33509	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0053513	Nmdar2	NMDA receptor 2	NA
FBgn0053516	dpr3	defective proboscis extension response 3	NA
FBgn0053519	Unc-89	Unc-89	Unc-89 (Unc-89) encodes a titin-like protein located at the midline of the muscle thick filaments that is needed for assembly of a symmetrical sarcomere. It is involved in myogenesis and the Hippo signalling pathway. [Date last reviewed: 2018-11-15]
FBgn0053523	CG33523	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0053526	PNUTS	Phosphatase 1 nuclear targeting subunit	Phosphatase 1 nuclear targeting subunit (PNUTS) encodes a protein phosphatase 1 binding protein involved in developmental growth and gene expression. [Date last reviewed: 2019-09-26]
FBgn0053542	upd3	unpaired 3	"unpaired 3 (upd3) encodes a ""cytokine"" (secreted protein) of the Unpaired family that can bind and activate the JAK-STAT receptor encoded by dome. It is induced in hemocytes or in the intestine upon damage to regulate the repair response in these tissues through JAK-STAT activation. [Date last reviewed: 2019-03-21]"
FBgn0053554	Nipped-A	Nipped-A	NA
FBgn0053556	form3	formin 3	formin 3 (form3) encodes a protein that belongs to the formin family, which functions in various actin-based processes. It is involved in tracheal fusion. [Date last reviewed: 2019-03-07]
FBgn0053558	mim	missing-in-metastasis	missing-in-metastasis (mim) encodes a protein involved in guided cell migration via endocytosis inhibition of the product encoded by Cortactin. [Date last reviewed: 2019-09-26]
FBgn0053635	CG33635	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0053653	Cadps	Calcium-dependent secretion activator	NA
FBgn0053774	CG33774	NA	NA
FBgn0053867	His-Psi:CR33867	His-Psi:CR33867	NA
FBgn0053926	CG33926	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-10-13]
FBgn0053969	CG33969	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0053971	Ir62a	Ionotropic receptor 62a	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0053977	Dpm3	Dolichyl-phosphate mannosyltransferase subunit 3	NA
FBgn0053978	CG33978	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0053987	lncRNA:CR33987	long non-coding RNA:CR33987	NA
FBgn0054001	CG34001	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0054003	NimB3	Nimrod B3	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0054015	CG34015	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0054039	CG34039	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0054056	CG34056	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0058002	ND-AGGG	NADH dehydrogenase (ubiquinone) AGGG subunit	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0058006	CG40006	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0058045	CG40045	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0058160	CG40160	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0058191	CG40191	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0058263	MFS17	Major Facilitator Superfamily Transporter 17	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0058354	CR40354	NA	NA
FBgn0058439	CG40439	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0058469	lncRNA:CR40469	long non-coding RNA:CR40469	NA
FBgn0058470	CG40470	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0060296	pain	painless	painless (pain) encodes a non-selective cation channel in the TRPA family that is required for the detection of noxious heat and mechanical stimuli. [Date last reviewed: 2018-11-15]
FBgn0061196	CG15468	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0061198	HSPC300	Haematopoietic stem/progenitor cell protein 300	Haematopoietic stem/progenitor cell protein 300 (HSPC300) encodes a subunit of the Scar/WAVE complex, which activates the Arp2/3 complex at the plasma membrane to generate membrane protrusions that drive cell migration. [Date last reviewed: 2019-03-07]
FBgn0061200	Nup153	Nucleoporin 153kD	NA
FBgn0061469	Ube3a	Ubiquitin protein ligase E3A	Ubiquitin protein ligase E3A (Ube3a) encodes the founding member of the HECT-type ubiquitin E3 ligase family of enzymes. It is involved in the final step of conjugation of ubiquitin to its target substrates. It regulates protein degradation by targeting modified proteins to the proteasome or by regulating the proteasome activity through ubiquitination of its subunits, which in turn affects many aspects of neuronal function, such as synaptic plasticity, long-term memory or dendritic development. [Date last reviewed: 2019-02-28]
FBgn0061476	Zwilch	Zwilch	Zwilch (Zwilch) encodes a subunit of the RZZ complex located at the kinetochores of chromosomes. The RZZ complex plays an essential role in the spindle assembly checkpoint that ensures proper connections between chromosomes and the mitotic spindle. [Date last reviewed: 2019-10-03]
FBgn0061492	loj	logjam	logjam (loj) encodes a p24-transporter-type protein involved in oviposition. [Date last reviewed: 2019-07-11]
FBgn0061515	endos	endosulfine	endosulfine (endos) encodes a protein that, after its phosphorylation by the kinase encoded by gwl, inhibits the phosphatase encoded by tws. This inhibition is important for the entry of cells into M phase during the cell cycle. [Date last reviewed: 2019-10-03]
FBgn0062413	Ctr1A	Copper transporter 1A	Copper transporter 1A (Ctr1A) encodes a plasma membrane protein that functions as a copper transporter. It is required to drive neuropeptide maturation during normal growth and development. [Date last reviewed: 2019-03-07]
FBgn0062440	EMRE	Essential MCU regulator	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0062442	Cisd2	CDGSH iron sulfur domain 2	NA
FBgn0062449	CG13197	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0062517	CG16984	NA	NA
FBgn0062928	hpRNA:CR33940	hairpin RNA:CR33940	NA
FBgn0063449	Uhg2	U snoRNA host gene 2	NA
FBgn0063485	Lasp	Lasp	Lasp (Lasp) encodes a member of the nebulin family. It plays subtle roles in modulating the actin cytoskeleton in ovaries, testes, and muscles, by serving as a scaffold protein binding multiple partners, especially actin and myosin. In indirect flight muscles, it contributes to I-band and A-band architecture. [Date last reviewed: 2019-03-14]
FBgn0063491	GstE9	Glutathione S transferase E9	Glutathione S transferase E9 (GstE9) encodes an enzyme involved in glutathione metabolic processes. [Date last reviewed: 2019-06-27]
FBgn0063492	GstE8	Glutathione S transferase E8	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0063493	GstE7	Glutathione S transferase E7	Glutathione S transferase E7 (GstE7) encodes a cytosolic enzyme that functions in detoxication. It has high catalytic activity with various isothiocyanates and the toxic environmental pollutants 2,4,6-trinitrotoluene (TNT) and 2,4-dinitrotoluene (DNT). [Date last reviewed: 2019-02-28]
FBgn0063494	GstE6	Glutathione S transferase E6	Glutathione S transferase E6 (GstE6) encodes an enzyme involved in glutathione metabolic processes. [Date last reviewed: 2019-06-27]
FBgn0063497	GstE3	Glutathione S transferase E3	Glutathione S transferase E3 (GstE3) encodes an enzyme involved in glutathione metabolic processes. [Date last reviewed: 2019-06-27]
FBgn0063498	GstE2	Glutathione S transferase E2	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0063649	CG6006	NA	NA
FBgn0063670	CG40228	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0063923	Kaz1-ORFB	Kaz1-ORFB	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0064225	RpL5	Ribosomal protein L5	Ribosomal protein L5 (RpL5) encodes a component of the large subunit of cytoplasmic ribosomes, which translate mRNAs encoded by the nuclear genome. RpL5 is haploinsufficient - heterozygous mutants display the 'Minute' phenotype, characterized by a slower developmental rate and small adult bristles. [Date last reviewed: 2019-03-14]
FBgn0064766	CG7600	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0065032	Arpc3B	Actin-related protein 2/3 complex, subunit 3B	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0065035	AlkB	AlkB	NA
FBgn0065099	snRNA:7SK	small nuclear RNA 7SK	NA
FBgn0066084	RpL41	Ribosomal protein L41	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0066114	GlcAT-I	Glucuronyltransferase I	NA
FBgn0067102	GlcT	Glucosylceramide synthase	Glucosylceramide synthase (GlcT) encodes an enzyme that catalyzes the formation of glucosylceramide, the core component of glycosphingolipids. It regulates lipid energy metabolism in fat body and plays critical roles in embryo survival and development. [Date last reviewed: 2019-03-07]
FBgn0067317	Cby	Chibby	Chibby (Cby) encodes a protein involved in ciliogenesis and basal body transition zone formation. [Date last reviewed: 2019-09-12]
FBgn0067628	CG33331	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0067629	CG33332	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0067779	dbr	debra	debra (dbr) encodes a transcriptional coactivator of various transcription factors, including the products of ci and dl. It contributes to developmental patterning, long-term memory, and cellular proliferation. [Date last reviewed: 2019-03-07]
FBgn0067783	DPCoAC	Dephosphocoenzyme A carrier	Dephosphocoenzyme A carrier (DPCoAC) encodes a mitochondrial carrier that transports dephosphocoenzyme A from the mitochondrial matrix to the cytosol where it is converted to coenzyme A. [Date last reviewed: 2019-02-28]
FBgn0067864	Patj	Patj	Patj (Patj) encodes a PDZ domain-protein that forms an apical protein complex with the products of crb and sdt. It plays supporting roles in apico-basal cell polarity and stability of adherens junction. It is also involved in retinal morphogenesis, maintenance, and planar cell polarity. [Date last reviewed: 2019-03-14]
FBgn0069242	eca	eclair	NA
FBgn0069973	CG40485	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0082582	tmod	tropomodulin	tropomodulin (tmod) encodes an actin/tropomyosin-associated protein involved in Notch signaling regulation. [Date last reviewed: 2019-09-26]
FBgn0082585	sprt	sprite	NA
FBgn0082598	akirin	akirin	NA
FBgn0082831	pps	protein partner of snf	protein partner of snf (pps) encodes a protein that is part of the machinery required for sex-specific splicing of the Sxl and tra pre-mRNAs. [Date last reviewed: 2019-03-14]
FBgn0083123	Uhg5	U snoRNA host gene 5	NA
FBgn0083124	Uhg4	U snoRNA host gene 4	NA
FBgn0083167	Neb-cGP	Neb-cGP	NA
FBgn0083953	CG34117	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0083961	CG34125	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0083962	CG34126	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0083968	CG34132	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0083969	CG34133	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0083970	CG34134	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0083977	CG34141	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-10-13]
FBgn0083983	mRpL34	mitochondrial ribosomal protein L34	NA
FBgn0083985	CG34149	NA	NA
FBgn0083986	CG34150	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0084001	CG41434	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-10-13]
FBgn0084049	CR41440	NA	NA
FBgn0085188	CG34159	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0085192	CG34163	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-10-13]
FBgn0085193	CG34164	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-10-13]
FBgn0085203	CG34174	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-10-13]
FBgn0085212	CG34183	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0085220	Ufm1	Ubiquitin-fold modifier 1	NA
FBgn0085223	CG34194	NA	NA
FBgn0085224	CG34195	NA	NA
FBgn0085229	CG34200	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0085242	CG34213	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0085249	CG34220	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0085257	CG34228	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0085261	CG34232	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-10-13]
FBgn0085279	CG34250	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-10-13]
FBgn0085334	CG34305	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-10-13]
FBgn0085350	inaF-C	inaF-C	inaF-C (inaF-C) encodes one of the four isoforms at the InaF locus, which contains four small ORFs named inaF-A, inaF-B, inaF-C, and inaF-D, each of which is spliced to the same down-stream exon. Mutations in inaF-C and inaF-B greatly suppress the expression of photoreceptor channel protein trp. inaF-C and inaF-B co-immunolocalize with trp to the rhabdomeres, structures containing the photoreceptors. [Date last reviewed: 2021-01-28]
FBgn0085354	CG34325	NA	NA
FBgn0085359	CG34330	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0085360	CG34331	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0085370	Pde11	Phosphodiesterase 11	NA
FBgn0085376	CG34347	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0085377	CG34348	NA	NA
FBgn0085384	CG34355	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0085386	CG34357	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0085390	Dgk	Diacyl glycerol kinase	NA
FBgn0085395	Shawl	Shaw-like	NA
FBgn0085405	CG34376	NA	NA
FBgn0085412	kmr	kramer	NA
FBgn0085421	Epac	Exchange protein directly activated by cAMP	Exchange protein directly activated by cAMP (Epac) encodes a guanine nucleotide exchange factor for the Ras-like small GTPases encoded by Rap1 and Rap2l. It is involved in transducing cAMP effects during synaptic potentiation, neuronal differentiation and renal secretion. [Date last reviewed: 2019-02-28]
FBgn0085423	GramD1B	GRAM domain containing 1B	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0085425	CG34396	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0085430	Dora	Dorado	NA
FBgn0085432	pan	pangolin	pangolin (pan) encodes an HMG-domain transcription factor that is a key component of the canonical Wingless signaling pathway. It toggles between acting as a transcriptional repressor (when bound to the product of gro) and activator (when bound to the product of arm) to promote cell fate specification. [Date last reviewed: 2019-03-14]
FBgn0085433	CG34404	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0085434	NaCP60E	Na channel protein 60E	Na channel protein 60E (NaCP60E) encodes a voltage-gated calcium-selective cation channel that likely modulates the stability of neural circuits, particularly under environmental stresses. [Date last reviewed: 2019-02-28]
FBgn0085436	Not1	Not1	Not1 (Not1) encodes a poly(A)-specific ribonuclease involved in translation inhibition and ovarian follicle cell development. [Date last reviewed: 2019-08-01]
FBgn0085437	CG34408	NA	NA
FBgn0085438	CG34409	NA	NA
FBgn0085442	NKAIN	Na,K-ATPase Interacting	NA
FBgn0085443	spri	sprint	NA
FBgn0085444	mute	muscle wasted	muscle wasted (mute) encodes a component of the histone locus body involved in muscle homeostasis. [Date last reviewed: 2019-09-26]
FBgn0085446	CG34417	NA	NA
FBgn0085450	Snoo	Sno oncogene	Sno oncogene (Snoo) encodes a protein that belongs to the highly conserved Sno/Ski family of Smad binding proteins. It specifically binds the product of Med and switches its affinity from the products of Mad to Smox, resulting in antagonism of the product of dpp and facilitation of Activin signaling. Snoo overexpression antagonizes both pathways. [Date last reviewed: 2019-03-14]
FBgn0085451	htk	hat-trick	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0085452	CG34423	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0085453	Mthfs	Methenyltetrahydrofolate synthetase	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0085459	CG34430	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0085460	CG34431	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-10-13]
FBgn0085466	CG34437	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0085468	ND-MWFE	NADH dehydrogenase (ubiquinone) MWFE subunit	NA
FBgn0085478	Zdhhc8	Zinc finger DHHC-type containing 8	NA
FBgn0085483	CG34454	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0085484	Pdxk	Pyridoxal kinase	Pyridoxal kinase (Pdxk) encodes the enzyme that generates Pyridoxal-5-phosphate, the metabolically active form of vitamin B6. It contributes to chromosome integrity and glucose homeostasis. [Date last reviewed: 2019-03-14]
FBgn0085638	CG41378	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-10-13]
FBgn0085732	CR40190	NA	NA
FBgn0085734	CR40450	NA	NA
FBgn0085742	CR40546	NA	NA
FBgn0085743	CR40560	NA	NA
FBgn0085757	CR40621	NA	NA
FBgn0085759	CR40640	NA	NA
FBgn0085764	CR40668	NA	NA
FBgn0085765	2SrRNA-Psi:CR40677	2S ribosomal RNA pseudogene:CR40677	NA
FBgn0085770	CR40734	NA	NA
FBgn0085773	CR40766	NA	NA
FBgn0085774	CR40779	NA	NA
FBgn0085795	CR41535	NA	NA
FBgn0085797	CR41540	NA	NA
FBgn0085799	CR41544	NA	NA
FBgn0085802	18SrRNA:CR41548	18S ribosomal RNA:CR41548	NA
FBgn0085805	CR41583	NA	NA
FBgn0085807	CR41590	NA	NA
FBgn0085813	18SrRNA-Psi:CR41602	18S ribosomal RNA pseudogene:CR41602	NA
FBgn0085815	CR41605	NA	NA
FBgn0085819	28SrRNA-Psi:CR41609	28S ribosomal RNA pseudogene:CR41609	NA
FBgn0085823	CR41617	NA	NA
FBgn0086031	snoRNA:Me28S-U1230	NA	NA
FBgn0086129	snama	something that sticks like glue	something that sticks like glue (snama) encodes a protein required for cell proliferation and survival in the developing eye. It is involved in apoptosis. [Date last reviewed: 2019-06-27]
FBgn0086130	Dbp21E2	DEAD box protein 21E2	DEAD box protein 21E2 (Dbp21E2) encodes an essential protein and a member of a family of DEAD box RNA helicases. Photoreceptors lacking Dbp21E2 function show defects in rhodopsin biogenesis and the maintenance of photoreceptors, leading to cell degeneration. [Date last reviewed: 2019-03-07]
FBgn0086134	Prosalpha2	Proteasome alpha2 subunit	NA
FBgn0086200	CR42490	NA	NA
FBgn0086251	del	deadlock	deadlock (del) encodes a protein that interacts with the products of rhi and cuff in a germline complex that allows noncanonical transcription of dual-strand piRNA clusters. It is therefore an integral part of the piRNA response to transposon activity in the germline. [Date last reviewed: 2019-03-07]
FBgn0086253	rumi	rumi	rumi (rumi) encodes an endoplasmic reticulum enzyme that adds a glucose residue to EGF-like repeats with a specific consensus sequence. It modulates the Notch signaling pathway and seems to regulate the function of other proteins, including the product of eys. [Date last reviewed: 2019-03-14]
FBgn0086254	Akr1B	Aldo-keto reductase 1B	NA
FBgn0086346	ALiX	ALG-2 interacting protein X	ALG-2 interacting protein X (ALiX) encodes an adaptor protein implicated in multiple cellular processes, including positive regulation of mitotic cytokinesis, exosomal secretion and apoptosis. [Date last reviewed: 2019-02-28]
FBgn0086347	Myo31DF	Myosin 31DF	NA
FBgn0086350	tef	teflon	teflon (tef) encodes a protein required for the maintenance of pairing between homologs at meiosis I, specifically in males. It is required for the localization of the product of mod(mdg4) to paired autosomal bivalents. [Date last reviewed: 2019-03-14]
FBgn0086355	Tpi	Triose phosphate isomerase	Triose phosphate isomerase (Tpi) encodes a soluble metabolic protein dimer that functions in glycolysis catalyzing the isomerization between dihydroxyacetone phosphate and glyceraldehyde 3-phosphate, which is essential for efficient ATP production. [Date last reviewed: 2019-03-14]
FBgn0086356	tum	tumbleweed	tumbleweed (tum) encodes a GTPase activating protein for Rho family GTPases involved in Wnt signalling regulation. [Date last reviewed: 2019-09-12]
FBgn0086357	Sec61alpha	Sec61 alpha subunit	Sec61 α subunit (Sec61α) encodes a subunit of the the translocon, a protein-conducting channel that mediates the co-translational transport of nascent polypeptides into the endoplasmic reticulum. It is a subunit of the Sec61 heterotrimer that forms the core of translocon channel. [Date last reviewed: 2019-03-14]
FBgn0086358	Tab2	TAK1-associated binding protein 2	TAK1-associated binding protein 2 (Tab2) encodes a protein with an ubiquitin binding domain. It interacts with the product of Tak1, a MAP kinase kinase kinase involved the activation of the immune deficiency, JNK and Grindelwald-Eiger pathways. [Date last reviewed: 2019-03-14]
FBgn0086359	Invadolysin	Invadolysin	Invadolysin (Invadolysin) encodes a metalloprotease that is required for mitosis, cell migration and mitochondrial function. [Date last reviewed: 2019-03-07]
FBgn0086361	alph	alphabet	alphabet (alph) encodes a Ser/Thr phosphatase that regulates RAS/MAPK signaling. [Date last reviewed: 2019-08-01]
FBgn0086362	spn-F	spn-F	spn-F (spn-F) encodes a coiled-coil protein that forms part of the IKKε-jvl complex. Its roles include actin and microtubule organization during oocyte development and bristle growth. [Date last reviewed: 2019-03-14]
FBgn0086365	Orct2	Organic cation transporter 2	Organic cation transporter 2 (Orct2) encodes an organic cation transporter of the major facilitator superfamily, and a transcriptional target of the insulin receptor pathway. [Date last reviewed: 2019-03-14]
FBgn0086370	sra	sarah	NA
FBgn0086371	poly	poly	poly (poly) encodes a mediator of the InR/TOR signaling pathway. Its functions include growth regulation, cell survival, cell polarization, and establishment/maintenance of interphase higher-order chromatin structures. [Date last reviewed: 2019-03-14]
FBgn0086372	lap	like-AP180	like-AP180 (lap) encodes a cytosolic protein that acts as a clathrin adaptor to promote clathrin-coated vesicle formation and restrict coated vesicle size. At synapses it regulates synaptic vesicle size as well as the efficacy of synaptic vesicle protein retrieval. [Date last reviewed: 2019-03-14]
FBgn0086378	Alg-2	Apoptosis-linked gene-2	NA
FBgn0086384	Mer	Merlin	Merlin (Mer) encodes a FERM domain containing protein that promotes assembly of a functional Hippo signaling complex at the apical cell cortex. It has also been associated with cell junctions and endocytic compartments. [Date last reviewed: 2019-02-28]
FBgn0086442	mib2	mind bomb 2	mind bomb 2 (mib2) encodes a protein required for regulating synaptic plasticity and memory formation and maintaining muscle integrity. [Date last reviewed: 2019-03-14]
FBgn0086443	AsnRS	Asparaginyl-tRNA synthetase	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0086444	l(2)37Cb	lethal (2) 37Cb	NA
FBgn0086445	l(2)37Cd	lethal (2) 37Cd	NA
FBgn0086446	DCTN6-p27	Dynactin 6, p27 subunit	NA
FBgn0086447	Polr1D	RNA polymerase I and III subunit D	NA
FBgn0086448	PIG-Q	Phosphatidylinositol glycan anchor biosynthesis class Q	Phosphatidylinositol glycan anchor biosynthesis class Q (PIG-Q) encodes a protein required for the biosynthesis of glycosylphosphatidylinositol, which is a component for anchoring eukaryotic proteins to membranes. [Date last reviewed: 2019-03-14]
FBgn0086450	su(r)	suppressor of rudimentary	suppressor of rudimentary (su(r)) encodes a dihydropyrimidine dehydrogenase, the first step of pyrimidine catabolism. su(r) depletion does not produce visible phenotypes, but synergistic effects are exhibited by combining mutants with genes affecting pyrimidine biosynthesis and beta-alanine metabolism. [Date last reviewed: 2019-09-26]
FBgn0086451	l(2)k09022	lethal (2) k09022	NA
FBgn0086472	RpS25	Ribosomal protein S25	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0086532	Spt-I	Serine palmitoyltransferase subunit I	NA
FBgn0086558	Ubi-p5E	Ubiquitin-5E	NA
FBgn0086605	CG9853	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0086608	CG34112	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-10-13]
FBgn0086613	Ino80	INO80 complex subunit	INO80 complex subunit (Ino80) encodes a component of the INO80 chromatin remodelling complex that interacts with Polycomb and Trithorax group proteins. It is involved in the regulation of homeotic gene expression and regression of ecdysone dependent transcription. [Date last reviewed: 2019-02-28]
FBgn0086655	jing	jing	NA
FBgn0086656	shrb	shrub	shrub (shrb) encodes Shrub encodes Vps32/Snf7, a filament-forming subunit of the ESCRT-III complex involved in inward membrane budding. It regulates multiple cellular processes involving ESCRTs activity including multivesicular body biogenesis, cytokinesis, membrane repair and regulation of membrane associated signaling. [Date last reviewed: 2019-03-14]
FBgn0086657	IKKepsilon	I-kappaB kinase epsilon	I-kappaB kinase ε (IKKε) encodes a serine-threonine kinase that targets the inhibitor of apoptosis encoded by Diap1 for degradation. It also negatively regulates protein kinase C and the dynein adaptor encoded nuf. The product of IKKε contributes to the specification of bristle cells, bristle cell morphogenesis, oocyte polarity, and dendrite development. [Date last reviewed: 2019-03-07]
FBgn0086674	Tpst	Tyrosylprotein sulfotransferase	NA
FBgn0086676	spin	spinster	spinster (spin) encodes a conserved transmembrane protein and a putative late-endosomal/lysosomal efflux permease. It is essential for mTOR reactivation and lysosome reformation following prolonged starvation and for regulation of TGF-β/BMP pathways in motoneuron and eye development. [Date last reviewed: 2019-03-14]
FBgn0086679	p	pink	NA
FBgn0086683	Spf45	Spf45	Spf45 (Spf45) encodes a bi-functional protein with roles in both splicing and DNA repair. [Date last reviewed: 2019-03-14]
FBgn0086686	l(3)L1231	lethal (3) L1231	NA
FBgn0086687	Desat1	Desaturase 1	Desaturase 1 (Desat1) encodes a transmembrane fatty acid desaturase that utilizes myristate and stearate (C16:0 and C18:0) to synthesize myristoleic and oleic acids (C16:1 and C18:1). It is involved in the synthesis of unsaturated fatty acids. [Date last reviewed: 2019-03-07]
FBgn0086690	Plp	Pericentrin-like protein	Pericentrin-like protein (Plp) encodes a protein localized to centrioles and centrosomes that plays an important role together with the product of cnn in organizing the pericentriolar material of the centrosome during interphase. It is also required for proper cilium function. [Date last reviewed: 2019-03-14]
FBgn0086691	UK114	UK114	NA
FBgn0086694	Bre1	Bre1	Bre1 (Bre1) encodes an E3 ubiquitin ligase that interacts with the E2 ubiquitin ligase encoded by Ubc6 to direct ubiquitination of histone H2B on lysine 120 at most RNA Polymerase II transcribed genes. It regulates Notch signaling. [Date last reviewed: 2019-03-07]
FBgn0086695	hd	humpty dumpty	humpty dumpty (hd) encodes a protein required for genomic DNA replication and developmental gene amplification. It localizes to subnuclear speckles, the nuclear envelope, and cytoplasmic bodies. [Date last reviewed: 2019-03-07]
FBgn0086698	frtz	fritz	fritz (frtz) encodes a cytoplasmic protein that functions as a planar polarity effector as a downstream member of the fz-stan planar cell polarity pathway that controls hair and bristle polarity. frtz protein directly binds to the product of in and accumulates on the proximal side of wing cells. [Date last reviewed: 2019-03-07]
FBgn0086706	pix	pixie	pixie (pix) encodes ABCE1, which is an ATPase that functions as a translation recycling factor. It is required for the assembly of complexes involved in translation initiation, and plays a role in the regulation of cellular and organismal growth. [Date last reviewed: 2019-03-14]
FBgn0086707	ncm	nucampholin	nucampholin (ncm) encodes a protein that is predicted to be an essential component of the spliceosome, implicated in regulation of pre-mRNA splicing and assembly of the exon junction complex. [Date last reviewed: 2019-05-16]
FBgn0086708	stv	starvin	starvin (stv) encodes a BAG family member that binds heat shock proteins. It plays roles in somatic muscles and is involved in the chaperone pathway essential for muscle maintenance. It also acts as co-chaperone of Hsp70 proteins during recovery from stress, including cold stress. [Date last reviewed: 2019-02-28]
FBgn0086710	RpL30	Ribosomal protein L30	NA
FBgn0086712	Egm	Enigma	Enigma (Egm) encodes a mitochondrial oxidoreductase involved in oxidative stress response and lipid homeostasis. [Date last reviewed: 2019-09-12]
FBgn0086757	cbs	centrosomin's beautiful sister	centrosomin's beautiful sister (cbs) encodes a a Golgi protein required for the centrosome cycle. [Date last reviewed: 2019-07-11]
FBgn0086758	chinmo	Chronologically inappropriate morphogenesis	Chronologically inappropriate morphogenesis (chinmo) encodes a putative BTB-zinc finger transcription factor. It is essential for neuronal temporal patterning. It also plays a role in the regulation of eye development, tumor formation, and the self-renewal and/or sexual identity of male somatic cyst stem cells by acting downstream of JAK-STAT signaling. [Date last reviewed: 2019-03-07]
FBgn0086768	Pcmt	Protein-L-isoaspartate (D-aspartate) O-methyltransferase	NA
FBgn0086779	step	steppke	steppke (step) encodes a member of the cytohesin family of guanine nucleotide exchange factors, which regulate small GTPases of the ADP-ribosylation factor (ARF) family. It contributes to multiple signaling pathways, such as Egfr, MAPK, PI3K and insulin signaling. It is involved in wing and eye development, germ cell segregation and cell growth. [Date last reviewed: 2019-03-14]
FBgn0086782	amn	amnesiac	amnesiac (amn) encodes an apparent pre-pro-neuropeptide that functions to prolong medium-term memory. In the adult, it is almost entirely concentrated in two large neurosecretory cells (Dorsal Paired Median cells). [Date last reviewed: 2019-02-28]
FBgn0086784	stmA	stambha A	NA
FBgn0086785	Vps36	Vacuolar protein sorting 36	Vacuolar protein sorting 36 (Vps36) encodes a component of the ESCRT-II complex. It interacts with the product of Vps28 (a component of the ESCRT-I complex), endosomal lipid PtdIns(3)P and Ubiquitin. [Date last reviewed: 2019-03-21]
FBgn0086855	CG17078	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-10-13]
FBgn0086856	CG11555	NA	NA
FBgn0086895	pea	peanuts	NA
FBgn0086904	Nacalpha	Nascent polypeptide associated complex protein alpha subunit	NA
FBgn0086906	sls	sallimus	sallimus (sls) encodes a large modular protein present in muscles. It links myosin filaments to the Z-disc. [Date last reviewed: 2019-03-14]
FBgn0086908	egg	eggless	eggless (egg) encodes a histone methyltransferase involved in epigenetic regulation of gene expression. It contributes to stem cell asymmetric division, oogenesis and wing disc development. [Date last reviewed: 2019-03-07]
FBgn0086909	CG31751	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0086912	mbm	mushroom body miniature	mushroom body miniature (mbm) encodes a zinc finger containing protein that localizes in the nucleolus. It plays a role in ribosome biogenesis. [Date last reviewed: 2019-03-14]
FBgn0087002	apolpp	apolipophorin	apolipophorin (apolpp) encodes an apolipoprotein of the ApoB family. It is complexed with lipids to assemble the major hemolymph lipoprotein, lipophorin. Lipophorin transports neutral lipids, phospholipids and sterols between tissues. Lipophorin also carries lipophilic hormones and signaling molecules. [Date last reviewed: 2019-03-07]
FBgn0087007	bbg	big bang	NA
FBgn0087008	e(y)3	enhancer of yellow 3	enhancer of yellow 3 (e(y)3) encodes a nuclear protein required for embryogenesis and oogenesis. It participates in gene activation in euchromatin as a component of both the SWI/SNF chromatin remodeling complex and the TFIID transcription coactivator. It also contributes to gene silencing in pericentric heterochromatin and is also a coactivator in the JAK/STAT pathway. [Date last reviewed: 2019-09-26]
FBgn0087011	CG41520	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0087013	Karybeta3	Karyopherin beta 3	NA
FBgn0087021	Spc25	Spc25	Spc25 (Spc25) encodes a component of the Ndc80 complex, which is an essential kinetochore constituent. [Date last reviewed: 2019-03-14]
FBgn0087035	AGO2	Argonaute 2	Argonaute 2 (AGO2) encodes an Argonaute/Piwi family protein, which interacts with small interfering RNAs (siRNAs) to form RNA-induced silencing complexes (RISCs). RISCs are guided to target and cleave transcripts (mostly from transposons and viruses). [Date last reviewed: 2019-03-07]
FBgn0087039	Sbp2	SECIS-binding protein 2	SECIS-binding protein 2 (Sbp2) encodes an RNA stem-loop binding protein involved in selenocysteine incorporation at a stop codon (UGA) during translation. [Date last reviewed: 2019-09-12]
FBgn0243511	psidin	phagocyte signaling impaired	NA
FBgn0243512	puc	puckered	puckered (puc) encodes a serine/threonine protein phosphatase that mediates a feedback loop that regulates the Jun-N-terminal kinase pathway. [Date last reviewed: 2019-03-14]
FBgn0243513	cnir	cornichon related	NA
FBgn0243514	eater	eater	eater (eater) encodes a transmembrane receptor of the Nimrod family specifically expressed in hemocytes and required for the phagocytosis of Gram positive bacteria and the attachment of hemocytes to sessile niches. [Date last reviewed: 2019-03-07]
FBgn0243516	Vrp1	Verprolin 1	Verprolin 1 (Vrp1) encodes the sole Drosophila homolog of the conserved Verprolin/WASp-interacting-protein family of actin regulators. It facilitates myoblast fusion in somatic muscles by recruiting the branched-actin polymerization machinery to sites of myoblast-myotube attachment and fusion. [Date last reviewed: 2019-03-21]
FBgn0250732	gfzf	GST-containing FLYWCH zinc-finger protein	GST-containing FLYWCH zinc-finger protein (gfzf) encodes encodes a glutathione binding protein that is predicted by phylogeny to have glutathione transferase activity. [Date last reviewed: 2019-03-07]
FBgn0250746	Prosbeta7	Proteasome beta7 subunit	NA
FBgn0250753	kra	krasavietz	krasavietz (kra) encodes a translational regulator that is able to interact with the translation initiation factor encoded by eIF2β. It is involved in axon guidance, long-term memory, and alcohol addiction. [Date last reviewed: 2019-03-14]
FBgn0250754	CG42232	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0250755	CG42233	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0250757	CG42235	NA	NA
FBgn0250785	vari	varicose	varicose (vari) encodes a protein involved in tracheal system development and septate junction assembly. [Date last reviewed: 2019-09-19]
FBgn0250786	Chd1	Chromodomain-helicase-DNA-binding protein 1	Chromodomain-helicase-DNA-binding protein 1 (Chd1) encodes an ATPase involved in the remodeling and assembly of chromatin. Its biological functions include regulation of gene transcription, incorporation of the histone variant H3.3 into paternal chromatin at fertilization and regulation of intestinal immunity and microbiota. [Date last reviewed: 2019-03-07]
FBgn0250788	beta-Spec	beta Spectrin	β Spectrin (β-Spec) encodes an essential protein that interacts with the product of α-Spec to form a heterotetramer. The product of β-Spec is typically associated with the plasma membrane. It functions in a lipoprotein pathway that delivers dietary fat to the larval fat body for storage. It is also believed to function in asymmetric division of germ line stem cells via cytoplasmic structures called spectrosomes and fusomes. [Date last reviewed: 2019-03-21]
FBgn0250789	alpha-Spec	alpha Spectrin	α Spectrin (α-Spec) encodes an essential protein that interacts with the products of β-Spec or kst to form a heterotetramer. It is typically associated with the plasma membrane. It functions in a lipoprotein pathway that delivers dietary fat to the larval fat body for storage. It is also believed to function in asymmetric division of germ line stem cells via cytoplasmic structures called spectrosomes and fusomes. [Date last reviewed: 2019-03-21]
FBgn0250791	alphaSnap	alpha Soluble NSF attachment protein	NA
FBgn0250814	UQCR-C2	Ubiquinol-cytochrome c reductase core protein 2	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0250816	AGO3	Argonaute 3	Argonaute 3 (AGO3) encodes a germline-specific Argonaute/Piwi family protein, which interacts with Piwi-interacting RNAs (piRNAs) to form effector complexes. It exhibits piRNA-guided RNA cleavage activity required for both piRNA amplification and transposon silencing, thereby securing germline development. [Date last reviewed: 2019-03-07]
FBgn0250819	CG33521	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0250820	meigo	medial glomeruli	medial glomeruli (meigo) encodes an evolutionarily conserved, multi-membrane pass protein that is mainly localized at the endoplasmic reticulum. meigo genetically interacts with Ephrin in dendrite targeting of olfactory projection neurons. [Date last reviewed: 2019-03-14]
FBgn0250821	CG14644	NA	NA
FBgn0250823	gish	gilgamesh	gilgamesh (gish) encodes a plasma membrane-associated kinase that regulates Hedgehog and Wingless signaling activity. It is involved in planar cell polarity via regulation of Rab11-mediated vesicle trafficking [Date last reviewed: 2019-08-01]
FBgn0250830	CG12547	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0250837	dUTPase	Deoxyuridine triphosphatase	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0250838	roh	reduction of Rh1	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0250843	Prosalpha6	Proteasome alpha6 subunit	NA
FBgn0250848	26-29-p	26-29kD-proteinase	NA
FBgn0250850	rig	rigor mortis	rigor mortis (rig) encodes a component of the cytoplasmic U snRNP body and a member of the SMN-Gemins complex. It is required in the motor system for viability and motor behaviour. It also works as a nuclear receptor interacting protein required for ecdysone signalling during larval development. [Date last reviewed: 2019-03-14]
FBgn0250867	CG42238	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0250868	CG42239	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0250869	CG42240	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-10-13]
FBgn0250874	ttm50	tiny tim 50	tiny tim 50 (ttm50) encodes a mitochondrial inner membrane protein that is involved in mitochondrial protein translocation and maintenance of mitochondrial membrane potential. It plays active roles in regulating metabolic levels for modulation of growth in development. [Date last reviewed: 2019-03-14]
FBgn0250906	Pgk	Phosphoglycerate kinase	Phosphoglycerate kinase (Pgk) encodes an enzyme involved in myoblast fusion. [Date last reviewed: 2019-09-26]
FBgn0250907	Cht10	Chitinase 10	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0259108	futsch	futsch	futsch (futsch) encodes a microtubule binding protein involved in the formation of synaptic buttons at the neuromuscular junctions. Its expression levels are regulated by the product of TBPH to prevent synaptic defects. [Date last reviewed: 2019-02-28]
FBgn0259110	mmd	mind-meld	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0259111	Ndae1	Na[+]-driven anion exchanger 1	Na[+]-driven anion exchanger 1 (Ndae1) encodes an intrinsic membrane protein that reversibly mediates the exchange of 1 Na[+] and 2 HCO[[3]][-] for 1 Cl[-] at basolateral membranes of gut and renal epithelia as well as CNS neurons. In the CNS, the product of Ndae1 can lower resting intracellular Cl[-] controlling GABA(A) Cl-channel activity. [Date last reviewed: 2019-09-26]
FBgn0259112	asRNA:CR42254	antisense RNA:CR42254	NA
FBgn0259113	PolA1	DNA polymerase alpha subunit 1	DNA polymerase alpha subunit 1 (PolA1) encodes the catalytic subunit of DNA polymerase alpha, responsible for initial synthesis on the leading strand and on each Okazaki fragment of the lagging strand. [Date last reviewed: 2019-09-26]
FBgn0259139	glo	glorund	glorund (glo) encodes a hnRNP F/H family RNA-binding protein that binds directly to nos mRNA and regulates its translation during late stages of oogenesis. The functions of the product of glo include nurse cell nuclear chromatin organization, axis patterning as well as being required for viability to adulthood. [Date last reviewed: 2019-03-07]
FBgn0259143	CG42258	NA	NA
FBgn0259152	Clbn	Caliban	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0259163	CG42268	NA	NA
FBgn0259164	CG42269	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0259166	CG42271	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0259167	CG42272	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-10-13]
FBgn0259168	mnb	minibrain	minibrain (mnb) encodes a Ser/Thr protein kinase of the DYRK subfamily. It interacts with several signaling pathways and it is involved in behavior, cell cycle, cytoskeleton dynamics, neural proliferation, neurogenesis, neuronal differentiation, synaptic plasticity, and tissue growth. [Date last reviewed: 2019-03-14]
FBgn0259170	alpha-Man-Ia	alpha-Mannosidase class I a	NA
FBgn0259171	Pde9	Phosphodiesterase 9	Phosphodiesterase 9 (Pde9) encodes a putative phosphodiesterase expressed in Malpighian tubules and involved in neurogenesis. [Date last reviewed: 2019-03-14]
FBgn0259173	corn	cornetto	cornetto (corn) encodes a microtubule binding protein involved in exocytosis regulation. [Date last reviewed: 2019-09-12]
FBgn0259174	Nedd4	Nedd4	Nedd4 (Nedd4) encodes an E3 ubiquitin ligase that negatively regulates the Notch signaling pathway and the genes comm, Amph. It contributes to neuromuscular synaptogenesis, transverse tubule formation in muscles, and in muscle function. [Date last reviewed: 2019-03-14]
FBgn0259175	ome	omega	omega (ome) encodes a dipeptidyl-peptidase. [Date last reviewed: 2019-09-12]
FBgn0259176	bun	bunched	NA
FBgn0259178	5PtaseI	Inositol polyphosphate-5-phosphatase type I	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0259212	cno	canoe	canoe (cno) encodes a scaffold protein in adherens junctions that is involved in morphogenesis in a variety of tissues. [Date last reviewed: 2019-03-07]
FBgn0259214	PMCA	plasma membrane calcium ATPase	plasma membrane calcium ATPase (PMCA) encodes a P-type ion pump found in the plasma membrane. It functions as a low-capacity, high-affinity Ca[2+]-extrusion mechanism, which is required for maintaining resting Ca[2+] levels in all cells. In the larval neuromuscular junction it plays an important role in restoring resting Ca[2+] levels after pre- or post-synaptic Ca[2+] influx. [Date last reviewed: 2019-03-14]
FBgn0259221	ATP8A	ATPase 8A	NA
FBgn0259224	CG42324	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0259227	CG42327	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0259228	C3G	C3G guanyl-nucleotide exchange factor	C3G guanyl-nucleotide exchange factor (C3G) is expressed in the developing embryonic muscles and its product plays a role in body wall muscle development during larval stages. [Date last reviewed: 2019-03-07]
FBgn0259233	CG42331	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0259237	CG42335	NA	NA
FBgn0259238	CG42336	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0259243	Pka-R1	Protein kinase, cAMP-dependent, regulatory subunit type 1	Protein kinase, cAMP-dependent, regulatory subunit type 1 (Pka-R1) encodes a cAMP-dependent protein kinase regulator that contributes to actin filament and microtubule organization. It is involved in neuromuscular synaptic transmission, molting and response to ethanol. [Date last reviewed: 2019-09-26]
FBgn0259246	brp	bruchpilot	bruchpilot (brp) encodes a cytoskeletal protein critical for structural integrity of electron-dense projection (T-bar) at pre-active zones. It contributes to Ca[2+] channel clustering, size regulation of the synaptic vesicle readily releaseable pool and anesthesia-resistant memory formation. [Date last reviewed: 2019-03-07]
FBgn0259481	Mob2	Mob2	Mob2 (Mob2) encodes a protein that belongs to the Mob1/phocein domain protein family. Its functions include rhabdomere determination during photoreceptor development. [Date last reviewed: 2019-03-14]
FBgn0259482	Mob3	MOB kinase activator 3	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0259483	Mob4	MOB kinase activator 4	MOB kinase activator 4 (Mob4) encodes a protein that contributes to microtubule organization, axonal transport, mitotic spindle assembly and regulation of Hippo signaling. [Date last reviewed: 2019-09-12]
FBgn0259676	Prim2	DNA primase subunit 2	DNA primase subunit 2 (Prim2) encodes a regulatory subunit of the DNA polymerase alpha-primase complex, which synthesizes short RNA-DNA primers on the lagging strand during DNA synthesis. [Date last reviewed: 2021-01-21]
FBgn0259677	CG42346	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0259683	Ir40a	Ionotropic receptor 40a	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0259685	crb	crumbs	crumbs (crb) encodes a transmembrane protein that binds to multiple proteins such as those encoded by sdt, par-6, AP-2α, yrt, ex and Moe. It contributes to organization of zonula adherens, epithelial morphogenesis, apico-basal cell polarity, and is a negative regulator of Notch activity and growth control via the Hippo pathway. In photoreceptor cells it is involved in morphogenesis, the trafficking of the product of ninaE and prevention of light-dependent photoreceptor degeneration. [Date last reviewed: 2019-03-07]
FBgn0259704	Nsun5	Nop2/Sun-like domain containing protein 5	Nop2/Sun-like domain containing protein 5 (Nsun5) encodes a protein predicted to catalyze the m5C-methylation of 28S ribosomal RNA. Nsun5 loss leads to increased lifespan and heat shock resistance. [Date last reviewed: 2019-03-14]
FBgn0259705	CG42359	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0259711	CG42365	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-10-13]
FBgn0259714	DIP-epsilon	Dpr-interacting protein epsilon	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0259715	CG42369	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0259728	CG42382	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0259734	Nost	Nostrin	Nostrin (Nost) encodes a lipid binding protein involved in epithelial cell differentiation, plasma membrane tubulation and adherens junction organization. [Date last reviewed: 2019-09-12]
FBgn0259735	mtgo	miles to go	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0259736	CG42390	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-10-13]
FBgn0259740	CG42394	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-10-13]
FBgn0259742	CG42360	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0259745	wech	wech	wech (wech) encodes a member of the RBCC/TRIM family of cytoplasmic multidomain proteins. It is a regulator of integrin-mediated adhesion. It interacts with the products of rhea and Ilk, which are components of the integrin-cytoskeleton link. [Date last reviewed: 2019-03-21]
FBgn0259749	mmy	mummy	mummy (mmy) encodes an UDP-N-acetylglucosamine diphosphorylase. It functions in apical extracellular matrix formation by producing GlcNAc residues needed for chitin synthesis and protein glycosylation. It regulates cuticle production, tracheal morphogenesis, and axon guidance. [Date last reviewed: 2019-03-14]
FBgn0259785	pzg	putzig	putzig (pzg) encodes a nuclear protein that is involved in chromatin activation of replication related genes and signalling pathways including Notch, Ecdysone and JAK/STAT. It regulates growth, cell death and various developmental processes. [Date last reviewed: 2019-03-14]
FBgn0259791	bora	aurora borealis	aurora borealis (bora) encodes a binding partner of the product of aurA. It is required for spindle orientation and asymmetric cell division. [Date last reviewed: 2019-03-07]
FBgn0259818	CG42399	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0259821	CG42402	NA	NA
FBgn0259824	Hip14	Huntingtin-interacting protein 14	NA
FBgn0259834	out	outsiders	outsiders (out) encodes a monocarboxylate transporter involved in programmed cell death of primordial germ cell/pole cells. [Date last reviewed: 2019-02-28]
FBgn0259876	Cap-G	Chromosome associated protein G	Chromosome associated protein G (Cap-G) encodes a component of the condensin I complex, necessary for accurate mitotic and meiotic chromosome segregation. [Date last reviewed: 2019-03-07]
FBgn0259896	NimC1	Nimrod C1	NA
FBgn0259916	CG42445	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-10-13]
FBgn0259923	Septin4	Septin 4	NA
FBgn0259935	CG42458	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0259936	Uhg3	U snoRNA host gene 3	NA
FBgn0259937	Nop60B	Nucleolar protein at 60B	Nucleolar protein at 60B (Nop60B) encodes a pseudouridine synthase that is a core component of H/ACA small nucleolar ribonucleoproteins (snoRNPs) and small Cajal body-specific ribonucleoproteins (scaRNPs). It is involved in pseudouridylation of cellular RNA, ribosome biogenesis, translation efficiency, cell proliferation, stress response and stem cell maintenance. [Date last reviewed: 2019-02-28]
FBgn0259938	cwo	clockwork orange	clockwork orange (cwo) encodes a basic-helix-loop-helix-Orange transcription factor that can both activate and repress transcription. It regulates rhythmic gene expression within the transcriptional feedback loop that keeps circadian time. [Date last reviewed: 2019-02-28]
FBgn0259977	Tdc1	Tyrosine decarboxylase 1	Tyrosine decarboxylase 1 (Tdc1) encodes a protein involved in behavioral response to ethanol. [Date last reviewed: 2019-07-11]
FBgn0259978	vlc	vulcan	vulcan (vlc) is induced above a basal level by 20-hydroxyecdysone in late third instar larvae. Its mutants die primarily as pharate adults with defects in ecdysone-induced leg morphogenesis. [Date last reviewed: 2019-03-21]
FBgn0259982	Uxt	Uxt prefoldin-like subunit	Uxt prefoldin-like subunit (Uxt) encodes a protein that suppresses growth of larval neuromuscular junctions via an unknown mechanism. [Date last reviewed: 2019-03-21]
FBgn0259984	kuz	kuzbanian	kuzbanian (kuz) encodes an ADAM metalloendopeptidase that regulates activation of the receptors encoded by N and robo1 by cleavage. [Date last reviewed: 2019-09-26]
FBgn0259985	Mppe	Metallophosphoesterase	Metallophosphoesterase (Mppe) encodes a Mg[2+]- or Mn[2+]-dependent serine/threonine phosphatase. [Date last reviewed: 2019-03-14]
FBgn0259990	CG42487	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-10-13]
FBgn0259993	lncRNA:CR42491	long non-coding RNA:CR42491	NA
FBgn0259994	OtopLa	Otopetrin-like a	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0260003	Dys	Dystrophin	Dystrophin (Dys) encodes a cytoplasmic protein that connects the actin cytoskeleton to the extracellular matrix via the receptor encoded by Dg. In addition, the product of Dys serves as a cytoplasmic scaffold for the membrane localization of different signaling factors, including nos, which regulates expression of miRNAs to adapt cellular homeostasis to changes induced by stress and dystrophy. [Date last reviewed: 2019-09-26]
FBgn0260004	Snmp1	Sensory neuron membrane protein 1	Sensory neuron membrane protein 1 (Snmp1) encodes a member of the CD36 family of lipoprotein receptors. It is expressed in a subset of olfactory neurons. It is required for a normal olfactory response to the male-specific pheromone 11-cis vaccenyl acetate. [Date last reviewed: 2019-03-14]
FBgn0260005	wtrw	water witch	water witch (wtrw) encodes a protein involved in response to humidity and sound perception. [Date last reviewed: 2019-07-11]
FBgn0260006	drd	drop dead	drop dead (drd) encodes an integral membrane protein required for female fertility and for proper function of the gut and respiratory tracheae. [Date last reviewed: 2019-03-07]
FBgn0260008	UQCR-11	Ubiquinol-cytochrome c reductase 11 kDa subunit	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0260011	NimC4	Nimrod C4	Nimrod C4 (NimC4) encodes a transmembrane phagocytic receptor that binds phosphatidylserine exposed on apoptotic cells. Its roles include recognition and engulfment of apoptotic cells during development. [Date last reviewed: 2019-03-14]
FBgn0260012	pds5	precocious dissociation of sisters 5	precocious dissociation of sisters 5 (pds5) encodes a protein that interacts with the product of wapl to form the releasin complex, which enables sister chromatid separation at mitosis by removing the cohesin ring complex from chromosomes. The product of pds5 influences gene activation and silencing through interactions with cohesin. It is also required to initiate and/or maintain sister chromatid cohesion. [Date last reviewed: 2019-03-14]
FBgn0260049	flr	flare	flare (flr) encodes the Drosophila Actin Interacting protein 1. It functions with the product of tsr (cofillin) to promote F-actin disassembly. [Date last reviewed: 2019-03-07]
FBgn0260243	E(var)3-9	Enhancer of variegation 3-9	NA
FBgn0260388	CG42514	NA	NA
FBgn0260397	Su(var)3-3	Suppressor of variegation 3-3	Suppressor of variegation 3-3 (Su(var)3-3) encodes a member of the Lysine specific demethylase (LSD1/KDM1) family. It can function both as a transcriptional co-repressor and a co-activator. It demethylates histone H3K4-me2 and -me1 residues, and promotes heterochromatin formation by facilitating H3K9 methylation mediated by the product of Su(var)3-9. It is involved in fertility, wing patterning formation and bristle specification. [Date last reviewed: 2019-09-26]
FBgn0260399	gwl	greatwall	greatwall (gwl) encodes a kinase required for mitosis and female meiosis. It phosphorylates the product of endos, which then acts as a stoichiometric inhibitor of the PP2A B-type adaptor subunit encoded by tws. [Date last reviewed: 2019-03-07]
FBgn0260400	elav	embryonic lethal abnormal vision	embryonic lethal abnormal vision (elav) encodes the founding member of a family of prototype RNA binding proteins homologous to human Hu proteins, and acting as gene-specific regulators of many aspects of mRNA processing. Drosophila has three members in this family, elav, fne and Rbp9, which are predominantly pan-neuronal. elav has roles in axon guidance, synapse formation and photoreceptor differentiation. [Date last reviewed: 2020-08-20]
FBgn0260407	mRpS23	mitochondrial ribosomal protein S23	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0260429	CG42524	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0260439	Pp2A-29B	Protein phosphatase 2A at 29B	Protein phosphatase 2A at 29B (Pp2A-29B) encodes the structural A subunit of the trimeric PP2A phosphatase enzyme. It links the catalytic C subunit encoded by mts and a variable regulatory B family subunit, which directs the enzyme to distinct substrates. The roles of Pp2A-29B product include centriole duplication, chromosome segregation, autophagy, axonal transport, growth regulation, and active zone stabilization. [Date last reviewed: 2019-02-28]
FBgn0260442	rhea	rhea	rhea (rhea) encodes fly talin, a large adaptor protein that is essential for all adhesive functions of integrins. It also has at least one role independent of integrins: repressing shg transcription in follicle cells. [Date last reviewed: 2019-03-14]
FBgn0260444	Not10	CCR4-NOT transcription complex subunit 10	NA
FBgn0260450	CalpC	Calpain C	Calpain C (CalpC) encodes one of four calcium-dependent cysteine proteases, but lack of conservation in the catalytic domain suggests it lacks proteolytic activity. [Date last reviewed: 2019-03-07]
FBgn0260456	CG4806	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0260462	CtsF	Cathepsin F	NA
FBgn0260463	Unc-115b	Uncoordinated 115b	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0260475	CG30059	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0260484	HIP	Hsc/Hsp70-interacting protein	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0260486	Ziz	Zizimin	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0260632	dl	dorsal	dorsal (dl) encodes a transcription factor that functions with the product of Dif, downstream of the Toll pathway. It contributes to certain functions of the Toll pathway, notably the dorsoventral patterning of early embryo. [Date last reviewed: 2019-03-07]
FBgn0260634	eIF4G2	eukaryotic translation initiation factor 4G2	eukaryotic translation initiation factor 4G2 (eIF4G2) encodes an eIF4G homolog involved in regulation of translation initiation within male germ cells. It is required for spermatogenesis. [Date last reviewed: 2019-09-12]
FBgn0260635	Diap1	Death-associated inhibitor of apoptosis 1	Death-associated inhibitor of apoptosis 1 (Diap1) encodes an E3 ubiquitin ligase with a caspase inhibitor activity that is involved in the control of apoptosis. [Date last reviewed: 2019-03-07]
FBgn0260639	gammaTub23C	gamma-Tubulin at 23C	NA
FBgn0260648	Rrp40	Ribosomal RNA processing 40	Ribosomal RNA processing 40 (Rrp40) encodes a protein involved in gene expression regulation. [Date last reviewed: 2019-07-11]
FBgn0260655	l(3)76BDm	lethal (3) 76BDm	NA
FBgn0260658	CG42541	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0260659	CG42542	NA	NA
FBgn0260722	lncRNA:CR42549	long non-coding RNA:CR42549	NA
FBgn0260741	CG3281	NA	NA
FBgn0260742	CG12213	NA	NA
FBgn0260743	GC1	Glutamate Carrier 1	Glutamate Carrier 1 (GC1) encodes a carrier protein of the inner mitochondrial membrane that transports L-glutamate either with H[+] or in exchange for OH[-]. It operates during uricogenesis and has an essential role in the mitochondrial glutamate metabolism. [Date last reviewed: 2019-03-07]
FBgn0260744	Tango9	Transport and Golgi organization 9	NA
FBgn0260745	mfas	midline fasciclin	midline fasciclin (mfas) encodes a protein involved in axonogenesis and regulation of hemocyte proliferation. [Date last reviewed: 2019-09-26]
FBgn0260746	Ect3	Ectoderm-expressed 3	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0260747	Chchd2	Coiled-coil-helix-coiled-coil-helix domain containing 2	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0260748	CG5004	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0260749	Utx	Utx histone demethylase	Utx histone demethylase (Utx) encodes a Jumonji C containing protein that catalyzes the removal of methyl groups from Histone H3 lysine 27. Together with the products of trr and Lpt, it is thought to regulate chromatin structure at transcriptional enhancers. [Date last reviewed: 2019-03-21]
FBgn0260750	Mulk	Multi-substrate lipid kinase	Multi-substrate lipid kinase (Mulk) encodes a ceramide kinase involved in ceramide metabolism and pole cell migration. [Date last reviewed: 2019-09-12]
FBgn0260755	CG42553	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0260756	CG42554	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0260767	CG42565	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0260768	CG42566	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0260771	Larp7	La related protein 7	La related protein 7 (Larp7) encodes an obligate component of the 7SK snRNP. The 7SK snRNP plays an essential role in RNA polymerase II elongation control by regulating the activity of the positive transcription elongation factor complex encoded by Cdk9 and CycT. [Date last reviewed: 2019-03-14]
FBgn0260779	GatA	Glutamyl-tRNA amidotransferase, subunit A	NA
FBgn0260789	mxc	multi sex combs	multi sex combs (mxc) encodes a Cylin E/Cdk2 substrate and molecular scaffold that is necessary for assembly of the histone locus body, which is a nuclear body associated with replication dependent histone gene clusters that contains factors necessary for the transcription and processing of histone mRNA. [Date last reviewed: 2019-03-14]
FBgn0260793	2mit	2mit	2mit (2mit) encodes a putative leucine-rich repeat transmembrane protein that is mainly expressed in the developing central nervous system. In the adult, it has a role in short-term memory. [Date last reviewed: 2019-03-07]
FBgn0260794	ctrip	circadian trip	circadian trip (ctrip) encodes a HECT ubiquitin ligase that regulates the levels and circadian oscillations of the transcriptional activator encoded by Clk. It plays a role in the control of rest-activity rhythms. [Date last reviewed: 2019-03-07]
FBgn0260798	Gprk1	G protein-coupled receptor kinase 1	NA
FBgn0260799	p120ctn	Adherens junction protein p120	Adherens junction protein p120 (p120ctn) encodes an important modulator of cell adhesion. It binds to and stabilizes classic cadherin cell adhesion receptors at the cell surface. Unlike its mammalian homologs, it is non-essential but becomes essential if the levels of the product of shg are reduced. [Date last reviewed: 2019-03-14]
FBgn0260817	gkt	glaikit	glaikit (gkt) encodes a member of the phospholipase D superfamily. It is essential for the formation of epithelial polarity and nervous system development. [Date last reviewed: 2019-03-07]
FBgn0260855	Sec22	Secretory 22	Secretory 22 (Sec22) encodes a protein involved in Wnt protein secretion. [Date last reviewed: 2019-07-11]
FBgn0260856	Membrin	Membrin	NA
FBgn0260857	Bet1	Blocked early in transport 1	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0260858	Ykt6	YKT6 v-SNARE	NA
FBgn0260859	Bet3	Blocked early in transport 3	Blocked early in transport 3 (Bet3) encodes a protein involved in dsRNA transport. [Date last reviewed: 2019-07-11]
FBgn0260860	Bet5	Blocked early in transport 5	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0260861	Trs23	TRAPP subunit 23	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0260862	Vti1a	Vesicle transport through interaction with t-SNAREs 1a	Vesicle transport through interaction with t-SNAREs 1a (Vti1a) encodes a protein involved in vesicle trafficking. [Date last reviewed: 2019-07-11]
FBgn0260866	dnr1	defense repressor 1	defense repressor 1 (dnr1) encodes a protein that interacts with the caspase encoded by Dredd. The product of dnr1 is involved in attenuation of innate immune response and neuro-inflammation. [Date last reviewed: 2019-02-28]
FBgn0260874	Ir76a	Ionotropic receptor 76a	NA
FBgn0260933	rempA	reduced mechanoreceptor potential A	reduced mechanoreceptor potential A (rempA) encodes the IFT140 subunit of the IFT-A subcomplex. As such, it is a component of the conserved intraflagellar transport (IFT) mechanism and is needed to extend cilia above the cell surface. [Date last reviewed: 2019-03-14]
FBgn0260934	par-1	par-1	par-1 (par-1) encodes a protein kinase involved in multiple processes, including microtubule cytoskeleton organization, axis specification and cell polarity. It regulates hippo signaling and osk mRNA localization. [Date last reviewed: 2019-06-13]
FBgn0260935	Vps15	Vacuolar protein sorting 15	Vacuolar protein sorting 15 (Vps15) encodes a serine/threonine protein kinase that is a core component of the Vps34/class III PI3-Kinase complex. It is required for the production of PI3P and influences multiple vesicle trafficking pathways, including autophagy and endocytosis. [Date last reviewed: 2019-03-21]
FBgn0260936	scny	scrawny	NA
FBgn0260938	tay	tay bridge	tay bridge (tay) encodes a nuclear protein acting in the MAP kinase pathway by preventing the product of rl activation. It is present in most cell types, and accumulates strongly in differentiated neurons. [Date last reviewed: 2019-03-14]
FBgn0260940	lsn	larsen	larsen (lsn), also known as Vacuolar protein sorting 22, encodes a member of the ESCRT-II complex, which sorts certain endocytosed receptors for degradation via the multivesicular body. As part of this complex, it also has a role in bcd RNA localization. [Date last reviewed: 2019-03-14]
FBgn0260941	app	approximated	approximated (app) encodes a palmitoyltransferase involved in planar cell polarity. It regulates Fat signaling and the localization and activity of the product of d. [Date last reviewed: 2019-03-07]
FBgn0260944	Rbp1	RNA-binding protein 1	NA
FBgn0260945	Atg1	Autophagy-related 1	Autophagy-related 1 (Atg1) encodes a protein kinase that functions downstream of the product of Tor in the regulation of autophagy. [Date last reviewed: 2019-03-07]
FBgn0260959	MCPH1	Microcephalin	Microcephalin (MCPH1) encodes a BRCT domain-containing protein that acts in genome stability and cell cycle regulation. It is required to co-ordinate centrosome and nuclear division during rapid syncitial embryonic cell divisions. [Date last reviewed: 2019-02-28]
FBgn0260960	Baldspot	Baldspot	Baldspot (Baldspot) encodes a protein involved in spermatogenesis. [Date last reviewed: 2019-09-19]
FBgn0260962	pic	piccolo	piccolo (pic) encodes the Ddb1 protein, which functions to recruit substrate receptors to Cul4-based E3 ubiquitin ligase complexes, which catalyze the ubiquitylation and subsequent destruction of proteins that function in cell growth and proliferation as well as transcription, replication and repair of the genome. [Date last reviewed: 2019-03-14]
FBgn0260965	CG42588	NA	NA
FBgn0260970	Ubr3	Ubr3 ubiquitin ligase	NA
FBgn0260972	alc	alicorn	NA
FBgn0260985	RfC4	Replication factor C subunit 4	NA
FBgn0260986	mei-38	meiotic 38	meiotic 38 (mei-38) encodes a microtubule-associated protein that functions in mitosis and meiosis. [Date last reviewed: 2019-03-14]
FBgn0260987	vtd	verthandi	verthandi (vtd) encodes a subunit of the cohesin complex, which encircles sister chromatids after DNA replication and has multiple roles in the regulation of gene expression and DNA repair. [Date last reviewed: 2019-03-21]
FBgn0260990	yata	yata	NA
FBgn0260991	Incenp	Inner centromere protein	Inner centromere protein (Incenp) encodes a component of the chromosomal passenger complex, acting as a subunit that targets and activates the product of aurB. It controls different processes during cell division, including regulation of chromosome structure, kinetochore-microtubule error correction, chromosome segregation and cytokinesis. [Date last reviewed: 2019-02-28]
FBgn0261004	asl	asterless	asterless (asl) encodes a component of the centriole that is required for centrosome function. It contributes to asymmetric cell division, sperm development and centriole replication and elongation. [Date last reviewed: 2019-03-07]
FBgn0261015	Pif1A	PFTAIRE-interacting factor 1A	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0261016	clos	closca	closca (clos) encodes a protein that is required, together with the products of fs(1)N and fs(1)M3, for their accumulation at the vitelline membrane and function in vitelline membrane integrity and Torso receptor activation. [Date last reviewed: 2019-03-07]
FBgn0261020	wol	wollknaeuel	wollknaeuel (wol) encodes a protein belonging to the the glycosyltransferase 2 family. It contributes to N-glycan biosynthesis and is involved in epidermal differentiation including maintenance of cell polarity and cuticle formation. [Date last reviewed: 2019-03-21]
FBgn0261041	stj	straightjacket	straightjacket (stj) encodes a voltage-gated calcium channel subunit involved in neuromuscular junction development and autophagosome maturation. [Date last reviewed: 2019-09-12]
FBgn0261049	Vps45	Vacuolar protein sorting 45	Vacuolar protein sorting 45 (Vps45) encodes an SM protein that is activated by the product of Rab5 and binds to the product of Rbsn-5 to control entry of endocytosed cargo into the early endosome. [Date last reviewed: 2019-03-21]
FBgn0261053	Cad86C	Cadherin 86C	Cadherin 86C (Cad86C) encodes a member of the cadherin superfamily of transmembrane proteins, which mediate cell-cell adhesion and/or cell-cell communication. [Date last reviewed: 2019-03-07]
FBgn0261064	Rbsn-5	Rabenosyn-5	Rabenosyn-5 (Rbsn-5) encodes a Rab5-binding effector that controls entry of endocytosed cargo into the early endosome. [Date last reviewed: 2019-03-14]
FBgn0261065	Cpsf73	Cleavage and polyadenylation specificity factor 73	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0261067	LSm1	Like Sm 1	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0261068	LSm7	Like Sm 7	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0261108	Atg13	Autophagy-related 13	Autophagy-related 13 (Atg13) encodes a subunit of the evolutionarily conserved Atg1 kinase complex, which controls the initiation of autophagosome formation. [Date last reviewed: 2019-03-07]
FBgn0261109	mrn	marionette	marionette (mrn) encodes a subunit of the basal transcription and DNA repair factor TFIIH. [Date last reviewed: 2019-03-14]
FBgn0261111	BHD	Birt-Hogg-Dube	Birt-Hogg-Dube (BHD) encodes a protein involved in the maintenance of germ-line stem cells and the regulation of nucleolar large rRNA transcription. [Date last reviewed: 2019-09-19]
FBgn0261112	APP-BP1	beta-Amyloid precursor protein binding protein 1	NA
FBgn0261113	Xrp1	Xrp1	Xrp1 (Xrp1) encodes an AT-Hook, bZip DNA binding protein involved in genome stability maintenance. It heterodimerizes with the product of Irbp18 to bind to P element sequences contributing to transposition. It is induced by p53 following X-irradiation and by mutations or knockdown of caz or ribosomal protein (Rp) encoding genes. It contributes to the slow growth of Minute (Rp+/-) mutants cell-autonomously by inhibiting translation and non-autonomously through regulation of the product of Ilp8. [Date last reviewed: 2019-05-16]
FBgn0261119	Prp19	Pre-RNA processing factor 19	Pre-RNA processing factor 19 (Prp19) encodes a protein involved in chromatin organization and alternative mRNA splicing regulation. [Date last reviewed: 2019-07-11]
FBgn0261238	Alh	Alhambra	Alhambra (Alh) encodes a zinc finger/leucine zipper nuclear protein. It is required in the nervous system for maintaining eve expression and normal growth. It is also involved in muscle development and male courtship behavior. [Date last reviewed: 2019-03-07]
FBgn0261239	Hr39	Hormone receptor-like in 39	Hormone receptor-like in 39 (Hr39) encodes a nuclear hormone receptor protein in subfamily 5. It is a master regulator of female reproductive gland development from the bipotential genital disc, and in adults is required for reproductive gland secretion, ovulation and additional functions. [Date last reviewed: 2019-03-07]
FBgn0261243	Psa	Puromycin sensitive aminopeptidase	NA
FBgn0261244	inaE	inactivation no afterpotential E	inactivation no afterpotential E (inaE) encodes a diacylglycerol lipase involved in phototransduction and response to oxidative stress. [Date last reviewed: 2019-03-07]
FBgn0261258	rgn	regeneration	NA
FBgn0261260	mgl	Megalin	Megalin (mgl) encodes a protein involved in cuticle development and endocytosis regulation. [Date last reviewed: 2019-09-26]
FBgn0261261	plx	pollux	pollux (plx) encodes a Rab GTPase activating protein involved in cell adhesion mediated by integrins. [Date last reviewed: 2019-08-01]
FBgn0261266	zuc	zucchini	zucchini (zuc) encodes a member of the phospholipase D superfamily. It is anchored in the outer mitochondrial membrane and functions in the processing of primary piRNA transcripts through its endonuclease activity. zuc depletion causes sterility, transposon de-repression and accumulation of piRNA cluster transcripts. [Date last reviewed: 2019-03-21]
FBgn0261268	Cul3	Cullin 3	NA
FBgn0261269	conv	convoluted	convoluted (conv) encodes a leucine-rich repeat protein involved in axon guidance and the development of the tracheal system. [Date last reviewed: 2019-09-19]
FBgn0261270	Sps1	Selenophosphate synthetase 1	Selenophosphate synthetase 1 (Sps1) encodes a protein that inhibits Gs1 and dmGlut expression, which in turn regulates the intracellular levels of glutamine. [Date last reviewed: 2019-07-25]
FBgn0261274	Ero1L	Endoplasmic reticulum oxidoreductin-1-like	Endoplasmic reticulum oxidoreductin-1-like (Ero1L) encodes a thiol oxidase that plays an important role in disulfide-bond formation. It oxidizes Pdi and mediates the oxidative protein folding in the endoplasmic reticulum. [Date last reviewed: 2021-01-21]
FBgn0261276	Opa1	Optic atrophy 1	Optic atrophy 1 (Opa1) encodes a dynamin-related GTPase that mediates fusion of the inner membrane of mitochondria. It usually works with the product of Marf to coordinately fuse both mitochondrial membranes. The product of Opa1 activity is regulated by proteolytic processing. [Date last reviewed: 2019-03-14]
FBgn0261278	grp	grapes	grapes (grp) encodes a protein that functions in a cell cycle checkpoint pathway that responds to DNA damage. [Date last reviewed: 2019-03-07]
FBgn0261279	lqfR	liquid facets-Related	liquid facets-Related (lqfR) encodes a Golgi protein involved in cell proliferation and oogenesis. [Date last reviewed: 2019-09-19]
FBgn0261283	SREBP	Sterol regulatory element binding protein	Sterol regulatory element binding protein (SREBP) encodes a membrane protein that functions as a master-regulator of lipogenesis. It activates transcription of lipogenic genes upon reduction of lipid or cholesterol levels. [Date last reviewed: 2019-02-28]
FBgn0261284	bou	boudin	boudin (bou) encodes a membrane glycoprotein of the Ly6 superfamily that is required for the formation of septate junctions in epithelial tissues. [Date last reviewed: 2019-03-07]
FBgn0261285	Ppcs	Phosphopantothenoylcysteine synthetase	NA
FBgn0261286	Mat89Ba	Maternal transcript 89Ba	NA
FBgn0261363	PPO3	Prophenoloxidase 3	Prophenoloxidase 3 (PPO3) is expressed in lamellocytes (a type of hemocyte cell involved in encapsulation) and its product involved in the melanization reaction during wasp encapsulation. [Date last reviewed: 2019-03-14]
FBgn0261373	CG33228	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0261380	mRpL37	mitochondrial ribosomal protein L37	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0261383	IntS6	Integrator 6	NA
FBgn0261385	scra	scraps	scraps (scra) encodes a homolog of anilin, a conserved pleckstrin homology domain (PLEKH) containing protein that binds actin, nonmuscle myosin II and microtubules. It stabilizes the contractile ring and is required for completion of cytokinesis. [Date last reviewed: 2019-03-14]
FBgn0261387	CG17528	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0261394	Prosalpha3	Proteasome alpha3 subunit	NA
FBgn0261396	Rpn3	Regulatory particle non-ATPase 3	NA
FBgn0261397	didum	dilute class unconventional myosin	dilute class unconventional myosin (didum) encodes a class V unconventional myosin that binds actin and hydrolyzes ATP. It functions in mRNA localization in the oocyte, spermatid individualization during spermatogenesis, transport of pigment granules in photoreceptors and mitochondrial transport in neuronal cells. [Date last reviewed: 2019-02-28]
FBgn0261403	sxc	super sex combs	super sex combs (sxc) is a polycomb group gene that encodes a O-GlcNAc transferase involved in epigenetic gene silencing. [Date last reviewed: 2019-09-12]
FBgn0261436	DhpD	Dihydropterin deaminase	NA
FBgn0261437	CSN8	COP9 signalosome subunit 8	COP9 signalosome subunit 8 (CSN8) encodes the subunit 8 of the COP9 signalosome (CSN) and is essential for the stability of the complex. The CSN plays a central role in the regulation of E3-cullin RING ubiquitin ligases. [Date last reviewed: 2019-03-07]
FBgn0261439	SdhA	Succinate dehydrogenase, subunit A (flavoprotein)	Succinate dehydrogenase, subunit A (flavoprotein) (SdhA) encodes the FAD-containing subunit of the succinate dehydrogenase complex. It directly oxidizes succinate to fumarate and transfers the electrons to other subunits and eventually to quinones. [Date last reviewed: 2019-09-26]
FBgn0261444	CG3638	NA	NA
FBgn0261445	sgl	sugarless	NA
FBgn0261456	hpo	hippo	hippo (hpo) encodes a kinase in the Salvador-Warts-Hippo pathway. It controls tissue growth by controlling cell growth, proliferation and apoptosis. It has several roles in post-mitotic cells including fate specification of photoreceptors and tiling of dendritic neurons. [Date last reviewed: 2019-03-07]
FBgn0261458	capt	capulet	capulet (capt) encodes a conserved actin binding protein that functions across eukaryotes to negatively regulate actin filament assembly. Different types of actin filament formation are differentially affected by the loss of capt. [Date last reviewed: 2019-03-07]
FBgn0261461	RhoGAP18B	Rho GTPase activating protein at 18B	Rho GTPase activating protein at 18B (RhoGAP18B) encodes a protein that can act as a GTPase activating protein for several Rho GTPase and is involved in the regulation of actin dynamics. [Date last reviewed: 2019-08-01]
FBgn0261477	slim	scruin like at the midline	NA
FBgn0261479	nero	nero	nero (nero) encodes a deoxyhypusine hydroxylase enzyme that is required for the hypusination of eEF5 and is localized to the endoplasmic reticulum. It negatively regulates autophagy. [Date last reviewed: 2019-03-14]
FBgn0261509	haf	hattifattener	hattifattener (haf) encodes a large transmembrane leucine-rich repeat (LRR) protein whose mutants have variable motor axon defects in which ISNb motor axons fail to make the correct decisions at choice points. [Date last reviewed: 2019-03-07]
FBgn0261524	lic	licorne	licorne (lic) encodes a serine/threonine kinase that phosphorylates p38 MAP kinases. [Date last reviewed: 2019-02-28]
FBgn0261530	nbs	nbs	nbs (nbs) encodes a component of the conserved MRN complex, which plays an important role in the repair of DNA double strand breaks. The product of nbs is required to prevent chromosome breakage, interacts with the telomere capping complex and prevents telomeric fusions. [Date last reviewed: 2019-02-28]
FBgn0261532	cdm	cadmus	cadmus (cdm) encodes a member of the importin beta family of nucleocytoplasmic cargo shuttling proteins. It functions at the neuromuscular junction to maintain normal subsynaptic reticulum structure and presynaptic probability of release. [Date last reviewed: 2019-03-07]
FBgn0261535	l(2)34Fd	lethal (2) 34Fd	NA
FBgn0261545	CG42663	NA	CG42663 encodes a Nck-associated protein 5-like protein involved in determination of lifespan. [Date last reviewed: 2019-03-07]
FBgn0261547	Exn	Ephexin	Ephexin (Exn) encodes a Eph-specific RhoGEF involved olfactory map formation. [Date last reviewed: 2019-08-01]
FBgn0261549	rdgA	retinal degeneration A	retinal degeneration A (rdgA) encodes a diacylglycerol kinase that mediates the conversion of diacylglycerol to phosphatidic acid. It contributes to phospholipase C based signalling reactions, controlling ion channel activity and protein transport. [Date last reviewed: 2019-03-14]
FBgn0261550	CG42668	NA	NA
FBgn0261552	ps	pasilla	pasilla (ps) encodes a nuclear RNA binding protein implicated in splicing. It is expressed at high levels in the embryonic salivary gland and other tissues. Loss of function results in a significant reduction in secretory volume and secretory vesicles in the salivary gland and irregular gland morphology. [Date last reviewed: 2019-03-14]
FBgn0261553	CG42671	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0261554	CG42672	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0261555	CG42673	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0261556	CG42674	NA	NA
FBgn0261560	Thor	Thor	Thor (Thor) encodes a eukaryotic translation initiation factor 4E binding protein that is controlled by the product of tor. It contributes to translation regulation, response to environmental stress and cell growth regulation. [Date last reviewed: 2019-03-14]
FBgn0261561	CG42675	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0261562	CG42676	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0261563	wb	wing blister	wing blister (wb) encodes one of 2 laminin α chains which assembles into a Laminin molecule. Laminin is an extracellular matrix component that interacts with integrins and mediates cell adhesion, guidance, signalling and basement membrane integrity. [Date last reviewed: 2019-03-21]
FBgn0261564	ReepA	Receptor expression enhancing protein A	Receptor expression enhancing protein A (ReepA) encodes a member of the DP1/Yop1p family. It localizes to the endoplasmic reticulum (ER) and is involved in the prevention of ER-stress. [Date last reviewed: 2019-03-14]
FBgn0261565	Lmpt	Limpet	NA
FBgn0261570	raskol	raskol	NA
FBgn0261573	CoRest	CoRest	CoRest (CoRest) encodes a DNA binding factor that controls transcription in cooperation with other transcriptional regulators. It positively modulates Notch signaling as well as showing co-repressor activity via histone modification regulation. [Date last reviewed: 2019-02-28]
FBgn0261574	kug	kugelei	kugelei (kug) (also known as Fat2 or Fat-like) encodes a member of the cadherin superfamily of transmembrane proteins, which mediate cell-cell adhesion and/or cell-cell communication. It is related to the product of ft and its roles include control of planar cell polarity, collective cell migration and morphogenesis. [Date last reviewed: 2019-03-14]
FBgn0261584	CG42694	NA	NA
FBgn0261592	RpS6	Ribosomal protein S6	Ribosomal protein S6 (RpS6) encodes a key component of the small (40S) ribosomal subunit. [Date last reviewed: 2019-02-28]
FBgn0261596	RpS24	Ribosomal protein S24	Ribosomal protein S24 (RpS24) encodes an essential component of the small ribosomal subunit that functions in protein synthesis. It is classified as a 'Minute' gene as heterozygous mutants exhibit a slower developmental rate and small adult bristles. [Date last reviewed: 2019-03-14]
FBgn0261597	RpS26	Ribosomal protein S26	NA
FBgn0261599	RpS29	Ribosomal protein S29	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0261602	RpL8	Ribosomal protein L8	Ribosomal protein L8 (RpL8) encodes a ribosomal structural constituent. [Date last reviewed: 2019-07-11]
FBgn0261608	RpL37A	Ribosomal protein L37A	NA
FBgn0261609	eIF2alpha	eukaryotic translation initiation factor 2 subunit alpha	eukaryotic translation initiation factor 2 subunit alpha (eIF2α) encodes one of three subunits of the eIF-2 complex required for the initiation of translation. eIF2α is classified as a 'Minute' gene as heterozygous mutants exhibit a slower developmental rate and small adult bristles. [Date last reviewed: 2019-03-07]
FBgn0261610	CG42699	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0261617	nej	nejire	nejire (nej) encodes the transcriptional co-activator CBP. It acetylates several nuclear proteins, including the histone encoded by His3 on K18, K27, and H4 on K8. By regulating gene expression, the product of nej has roles in cell proliferation, cell signaling and differentiation, and in developmental patterning. [Date last reviewed: 2019-03-14]
FBgn0261618	larp	La related protein	La related protein (larp) encodes a protein that associates and interacts with poly(A)-binding protein. It is required for multiple processes in male meiosis and syncytial embryo development. [Date last reviewed: 2019-02-28]
FBgn0261625	GLS	Glutaminase	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0261641	CG42724	NA	NA
FBgn0261647	Axud1	AXIN1 up-regulated 1	AXIN1 up-regulated 1 (Axud1) encodes a nuclear protein required to regulate cell proliferation rates and cell growth in the wing disc. [Date last reviewed: 2019-03-07]
FBgn0261649	tinc	tincar	tincar (tinc) encodes a transmembrane protein involved in the regulation of the development of ommatidial cells. tinc mRNA expression is negatively regulated by the product of svp in a cardioblast subpopulation. [Date last reviewed: 2019-03-14]
FBgn0261671	tweek	tweek	tweek (tweek) encodes a protein involved in the endocytosis of synaptic vesicles. [Date last reviewed: 2019-09-19]
FBgn0261673	nemy	no extended memory	no extended memory (nemy) likely encodes a human cytochrome b561 homolog and is involved in middle-term olfactory associative memory and courtship conditioning memory. [Date last reviewed: 2019-02-28]
FBgn0261674	CG42709	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0261703	gce	germ cell-expressed bHLH-PAS	germ cell-expressed bHLH-PAS (gce) encodes a bHLH-PAS domain transcription factor paralogous to the product of Met. It is a receptor for the sesquiterpenoid juvenile hormone. [Date last reviewed: 2019-03-07]
FBgn0261710	nocte	no circadian temperature entrainment	no circadian temperature entrainment (nocte) encodes a protein involved in temperature compensation of the circadian clock. [Date last reviewed: 2019-09-26]
FBgn0261722	fwe	flower	flower (fwe) encodes a transmembrane protein with different isoforms expressed in 'loser' and in 'winner' cells to mediate win/lose decisions in cell competition and neuronal culling during development and ageing. [Date last reviewed: 2019-02-28]
FBgn0261786	mi	minus	minus (mi) encodes a protein that can bind to the product of CycE and the SCF-ago ubiquitin-ligase complex. Minus regulates the turnover of the product of CycE and cell proliferation. [Date last reviewed: 2019-03-14]
FBgn0261787	brun	brunelleschi	NA
FBgn0261789	SmD2	Small ribonucleoprotein particle protein SmD2	Small ribonucleoprotein particle protein SmD2 (SmD2) encodes an RNA binding protein that forms a heterodimeric sub-complex with the product of SmD1. They function as part of the heteroheptameric ring complex Sm core, which is involved in the formation of spliceosomal small nuclear RNPs (U1, U2, U4 and U5), which together catalyze pre-mRNA splicing. [Date last reviewed: 2019-03-14]
FBgn0261790	SmE	Small ribonucleoprotein particle protein SmE	Small ribonucleoprotein particle protein SmE (SmE) encodes an RNA binding protein that functions as part of a heteroheptameric ring structure called the Sm core. This complex binds to spliceosomal small nuclear RNAs (e.g. U1, U2, U4 and U5) and helps to carry out pre-mRNA splicing. It also forms a heterotrimeric sub-complex with the products of SmF and SNRPG. [Date last reviewed: 2019-03-14]
FBgn0261791	SNRPG	Small nuclear ribonucleoprotein G	Small nuclear ribonucleoprotein G (SNRPG) encodes a Sm class protein and a common component of pre-mRNA processing U snRNPs. It forms the toroidal core of U snRNPs (Sm core domain) together with 6 related Sm proteins. [Date last reviewed: 2019-03-14]
FBgn0261792	snRNP-U1-C	small ribonucleoprotein particle U1 subunit C	small ribonucleoprotein particle U1 subunit C (snRNP-U1-C) encodes a U1 snRNA-containing protein that initiates spliceosome assembly by binding to the 5' splice site in pre-mRNA. [Date last reviewed: 2019-02-28]
FBgn0261793	Trf2	TATA box binding protein-related factor 2	TATA box binding protein-related factor 2 (Trf2) encodes a core promoter recognition factor that mediates gene transcription. It contributes to spiracle morphogenesis, pupal development and salivary gland cell death. [Date last reviewed: 2019-08-01]
FBgn0261794	kcc	kazachoc	kazachoc (kcc) encodes a potassium:chloride symporter that contributes to seizure susceptibility. [Date last reviewed: 2019-09-12]
FBgn0261797	Dhc64C	Dynein heavy chain 64C	Dynein heavy chain 64C (Dhc64C) encodes the heavy chain subunit of the cytoplasmic dynein motor complex. The product of Dhc64C forms a dimer, which binds and hydrolyzes ATP providing the power for movement of dynein. It has an essential function in oocyte polarity, mitotic cell division, embryonic development, and neuronal transport and neurogenesis. [Date last reviewed: 2019-03-07]
FBgn0261800	LanB1	LanB1	LanB1 (LanB1) encodes a subunit of laminin, a heterotrimeric protein found in the extracellular matrix (ECM) and a major component of the basal lamina. Laminins interact with a variety of cell surface molecules such as integrin receptors and other secreted ECM components. It contributes to ECM organization, tissue adhesion, cell motility and developmental patterning. [Date last reviewed: 2019-09-26]
FBgn0261802	CG42748	NA	NA
FBgn0261808	cu	curled	curled (cu) encodes a NADP/NADPH phosphatase. It is involved in NADP metabolism, mRNA poly(A) tail shortening and response to light. cu mutants has wings curved upward. [Date last reviewed: 2019-09-19]
FBgn0261811	pico	pico	pico (pico) encodes an intracellular adapter protein belonging to the MRL family of proteins, which transduce signals from growth factor receptors to changes in the actin cytoskeleton. Its roles include the regulation of growth and cell migration. [Date last reviewed: 2019-03-14]
FBgn0261822	Bsg	Basigin	Basigin (Bsg) encodes an IgG family glycoprotein that promotes cytoskeletal rearrangements and lamellipodia formation in cultured insect cells. It contributes to photoreceptor cell morphogenesis, sarcomere organization and spermatid development. [Date last reviewed: 2019-03-07]
FBgn0261823	Asx	Additional sex combs	Additional sex combs (Asx) encodes a chromatin binding protein with deubiquitination activity of the product of His2A. It genetically interacts with Pc and sxc and represses homeotic genes transcription. It contributes to antennal development and embryonic cell cycle. [Date last reviewed: 2019-03-07]
FBgn0261836	Msp300	Muscle-specific protein 300 kDa	Muscle-specific protein 300 kDa (Msp300) encodes a Nesprin-like protein that is required for proper positioning of muscle nuclei, mitochondria, and neuromuscular junction. [Date last reviewed: 2019-03-14]
FBgn0261844	pre-mod(mdg4)-V	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-10-13]
FBgn0261850	Xpd	Xeroderma pigmentosum D	Xeroderma pigmentosum D (Xpd) encodes a DNA helicase that is a subunit of the basal transcription and DNA repair factor TFIIH. [Date last reviewed: 2019-03-21]
FBgn0261854	aPKC	atypical protein kinase C	atypical protein kinase C (aPKC) encodes a member of the conserved Par complex and is asymmetrically localized to the apical cortex, where it phosphorylates and thus excludes the basal determinants encoded by mira and numb. It is involved in neuroblast proliferation and self-renewal. [Date last reviewed: 2019-03-07]
FBgn0261859	CG42788	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0261862	whd	withered	withered (whd) encodes a carnitine O-palmitoyltransferase involved in oxidative stress. [Date last reviewed: 2019-09-26]
FBgn0261872	scaf6	SR-related CTD associated factor 6	NA
FBgn0261873	sdt	stardust	stardust (sdt) encodes membrane-associated guanylate kinase (MAGUK) protein involved in the maintenance of apico-basal cell polarity and the organization of zonula adherens. [Date last reviewed: 2019-03-14]
FBgn0261881	Ankrd49	NA	NA
FBgn0261885	osa	osa	osa (osa) encodes a subunit of the BAP chromatin remodeling complex. It antagonizes Wnt target gene expression and limits the self-renewal of neural and intestinal stem cells. [Date last reviewed: 2019-03-14]
FBgn0261931	CG42797	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0261933	SmD1	Small ribonucleoprotein particle protein SmD1	Small ribonucleoprotein particle protein SmD1 (SmD1) encodes an RNA binding protein that forms a heterodimeric sub-complex with the product of SmD2. They function as part of the heteroheptameric ring complex Sm core, which is involved in the formation of spliceosomal small nuclear RNPs (U1, U2, U4 and U5), which together catalyze pre-mRNA splicing. [Date last reviewed: 2019-03-14]
FBgn0261934	dikar	dikar	dikar (dikar) encodes a protein involved in long-term memory. [Date last reviewed: 2019-09-12]
FBgn0261938	PolrMT	RNA polymerase mitochondrial	NA
FBgn0261954	east	enhanced adult sensory threshold	enhanced adult sensory threshold (east) encodes a ubiquitous protein localized to an extrachromosomal domain of the nucleus. It is involved in chemosensory behavior, chromosome segregation during cell division, cell survival and muscle development. [Date last reviewed: 2019-02-28]
FBgn0261955	kdn	knockdown	NA
FBgn0261975	CG42806	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-10-13]
FBgn0261976	Psf2	Partner of Sld Five 2	NA
FBgn0261983	l(2)gd1	lethal (2) giant discs 1	lethal (2) giant discs 1 (l(2)gd1) encodes a cytosolic protein conserved in Metazoa. It is involved in the transport of proteins such as signaling receptors through the endosomal pathway. It interacts with the ESCRT-III core component encoded by shrb and is probably required for its full activity. [Date last reviewed: 2019-09-26]
FBgn0261984	Ire1	Inositol-requiring enzyme-1	Inositol-requiring enzyme-1 (Ire1) encodes a transmembrane protein that mediates the unfolded protein response. Misfolded peptides in the endoplasmic reticulum activate the RNase activity of the product of Ire1, thereby promoting the cleavage of its downstream substrates, such as Xbp1 mRNA. The product of Ire1 is also required for photoreceptor differentiation. [Date last reviewed: 2019-03-07]
FBgn0261985	Ptpmeg	Protein tyrosine phosphatase Meg	Protein tyrosine phosphatase Meg (Ptpmeg) encodes a tyrosine phosphatase that interacts with the product of Eps-15. It negatively regulates border cell migration during oogenesis. It also inhibits the EGFR/Ras/mitogen-activated protein kinase signaling pathway during wing morphogenesis. [Date last reviewed: 2019-03-14]
FBgn0261986	RASSF8	Ras association domain family member 8	Ras association domain family member 8 (RASSF8) encodes a member of the N-terminal RASSF protein family. It localises with the product of ASPP at the adherens junctions of epithelial cells where it promotes junction stability by repressing Src activity via C-terminal Src kinase. [Date last reviewed: 2019-05-16]
FBgn0261988	Gprk2	G protein-coupled receptor kinase 2	G protein-coupled receptor kinase 2 (Gprk2) encodes a member of a family of serine/threonine kinases that modulate G-protein coupled receptors. It is required for female fertility, normal egg shape, and normal egg cAMP levels. It is also implicated in Hedgehog signaling and olfactory rhythmicity. [Date last reviewed: 2019-03-07]
FBgn0261995	CG42813	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0262028	lncRNA:CR42839	long non-coding RNA:CR42839	NA
FBgn0262035	CG42846	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-10-13]
FBgn0262057	Spn77Ba	Serpin 77Ba	Serpin 77Ba (Spn77Ba) encodes a serine protease inhibitor of the serpin family. It functions in the trachea in a protease cascade required for melanization, a host defense reaction against microbial pathogens. [Date last reviewed: 2019-03-14]
FBgn0262081	Csk	C-terminal Src kinase	C-terminal Src kinase (Csk) encodes a cytoplasmic tyrosine kinase that acts as a tumor suppressor through Src pathway inibition as well as a mediator of the activity of the product of Egfr. [Date last reviewed: 2019-03-07]
FBgn0262103	Sik3	Salt-inducible kinase 3	NA
FBgn0262108	lncRNA:CR42861	long non-coding RNA:CR42861	NA
FBgn0262109	lncRNA:CR42862	long non-coding RNA:CR42862	NA
FBgn0262114	RanBPM	Ran-binding protein M	Ran-binding protein M (RanBPM) encodes a protein involved in cell adhesion that regulates the shape, size, and organization of the germline stem cell niche in the ovary. [Date last reviewed: 2019-03-14]
FBgn0262115	CG17683	NA	NA
FBgn0262116	RNASEK	Ribonuclease kappa	Ribonuclease kappa (RNASEK) encodes a protein involved in clathrin-mediated endocytosis of large cargo, such as viruses. [Date last reviewed: 2019-05-16]
FBgn0262117	IntS3	Integrator 3	NA
FBgn0262123	l(2)41Ab	lethal (2) 41Ab	NA
FBgn0262124	uex	unextended	NA
FBgn0262125	Sec23	Secretory 23	Secretory 23 (Sec23) encodes a COPII vesicle-coating component that functions in vesicle transport from the ER to the Golgi apparatus. It is involved in cell polarity maintenance and extracellular matrix secretion. [Date last reviewed: 2019-08-01]
FBgn0262126	Sec24CD	Secretory 24CD	Secretory 24CD (Sec24CD) encodes a subunit of the coat protein complex of COPII vesicles, which transport cargo from the endoplasmic reticulum to the Golgi apparatus. It is essential for export of membrane and secreted proteins from the endoplasmic reticulum. It is involved in epithelial morphogenesis and differentiation. [Date last reviewed: 2019-03-14]
FBgn0262127	kibra	kibra	NA
FBgn0262160	CG9932	NA	NA
FBgn0262166	calypso	calypso	NA
FBgn0262167	ana1	anastral spindle 1	anastral spindle 1 (ana1) encodes a cytoplasmic protein located in the centrioles, including the sperm giant centriole and proximal centriole-like structure, which assists in centrioles formation. Its roles include coordinated movement behavior, sperm motility, and fertility. [Date last reviewed: 2019-03-07]
FBgn0262169	magu	magu	magu (magu) encodes a secreted protein that binds glypicans and regulates BMP signaling. It contributes to the regulation of growth and patterning of the wing, germ-line stem cell maintenance and adult life span. [Date last reviewed: 2019-03-14]
FBgn0262467	Scox	Synthesis of cytochrome c oxidase	Synthesis of cytochrome c oxidase (Scox) encodes a protein involved in cytochrome complex assembly and regulation of ATP biosynthesis. [Date last reviewed: 2019-09-19]
FBgn0262473	Tl	Toll	Toll (Tl) encodes a transmembrane receptor that activates the Tl intracellular signaling pathway upon binding the ligand encoded by spz. It is involved in dorso-ventral embryonic patterning and immunity. [Date last reviewed: 2019-03-14]
FBgn0262475	bru2	bruno 2	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0262483	Rbp	RIM-binding protein	RIM-binding protein (Rbp) encodes an active zone protein involved in neuromuscular synaptic transmission and presynaptic active zone organization. [Date last reviewed: 2019-09-19]
FBgn0262508	CG43078	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0262509	nrm	neuromusculin	neuromusculin (nrm) encodes a protein involved in synaptic target recognition. [Date last reviewed: 2019-09-26]
FBgn0262512	Vha14-1	Vacuolar H[+] ATPase 14kD subunit 1	NA
FBgn0262515	VhaAC45	Vacuolar H[+] ATPase AC45 accessory subunit	NA
FBgn0262517	Ltn1	Listerin E3 ubiquitin protein ligase 1	Listerin E3 ubiquitin protein ligase 1 (Ltn1) encodes an enzyme involved in ribosome quality control for co-translational degradation of the 'nonstop' proteins. It associates with the 60S ribosome subunit and ubiquitylates the peptidyl-tRNA so the nascent peptide can be degraded by the proteasome. [Date last reviewed: 2019-05-16]
FBgn0262518	Rab8	Rab8	Rab8 (Rab8) encodes a member of the Rab GTPase family that regulates the function of the recycling endosome, where it localizes. [Date last reviewed: 2019-05-16]
FBgn0262519	Mi-2	Mi-2	Mi-2 (Mi-2) encodes a nuclear ATP-dependent nucleosome remodeler of the CHD family. It associates with active chromatin and utilizes the energy of ATP hydrolysis to move nucleosomes along DNA. It is required for repression of cell type-specific genes, full activation of heat shock genes and regulates higher order chromatin structure of polytene chromosomes. [Date last reviewed: 2019-03-14]
FBgn0262524	ver	verrocchio	verrocchio (ver) encodes a member of the terminin complex, which prevents telomere fusions. It is required for telomere maintenance. [Date last reviewed: 2019-03-21]
FBgn0262527	nsl1	non-specific lethal 1	non-specific lethal 1 (nsl1) encodes a non-catalytic subunit of the NSL histone H4 acetyltransferase complex, and is involved in muscle development, oogenesis and regulation of endocytosis. [Date last reviewed: 2020-11-05]
FBgn0262534	CG43088	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0262559	Mdh2	Malate dehydrogenase 2	Malate dehydrogenase 2 (Mdh2) encodes one of the enzymes in the tricarboxylic acid cycle in mitochondria. [Date last reviewed: 2019-03-14]
FBgn0262560	wcd	wicked	wicked (wcd) encodes a member of the U3 snoRNP complex required for pre-ribosomal RNA maturation. It is involved in stem cell maintenance and function via regulation of cell size by ribosome synthesis. [Date last reviewed: 2019-05-16]
FBgn0262563	CG43103	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-10-13]
FBgn0262577	CG43117	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-10-13]
FBgn0262579	Sarm	Sterile alpha and Armadillo motif	Sterile alpha and Armadillo motif (Sarm) encodes an intracellular signaling molecule that is required for execution of a pro-degenerative pathway after axotomy. [Date last reviewed: 2019-03-07]
FBgn0262582	cic	capicua	capicua (cic) encodes an HMG-box family transcriptional repressor that serves as a general sensor of RTK signaling. cic-dependent gene silencing is alleviated by phosphorylation mediated by the product of rl, which causes the translocation of the product of cic from the nucleus to the cytoplasm. It governs gene expression in diverse processes including cell proliferation and specification. [Date last reviewed: 2019-03-07]
FBgn0262587	CG43124	NA	NA
FBgn0262588	CG43125	NA	NA
FBgn0262598	mtsh	mitoshell	mitoshell (mtsh) encodes a protein with a bromodomain-related region. It is required during spermatogenesis for proper temporal coordination of meiotic divisions with the morphogenetic events that usually follow meiosis. [Date last reviewed: 2019-05-16]
FBgn0262601	SmB	Small ribonucleoprotein particle protein SmB	Small ribonucleoprotein particle protein SmB (SmB) encodes an RNA binding protein that forms a heterodimeric sub-complex with the product of SmD3. They function as part of the heteroheptameric ring complex Sm core, which is involved in the formation of spliceosomal small nuclear RNPs (U1, U2, U4 and U5), which together catalyze pre-mRNA splicing. [Date last reviewed: 2019-03-14]
FBgn0262614	pyd	polychaetoid	polychaetoid (pyd) encodes a broadly acting protein that is associated with multiple proteins at the surface and within the cytoskeleton, connecting events between the two. [Date last reviewed: 2019-03-14]
FBgn0262617	Nuak	Nuak family kinase	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0262619	DNAlig1	DNA ligase 1	NA
FBgn0262620	lncRNA:CR43144	long non-coding RNA:CR43144	NA
FBgn0262636	dati	datilografo	datilografo (dati) encodes a conserved zinc finger transcription factor required for the differentiation of neurons in the ventral nerve cord and the brain. In adult brains, the product of dati is required in cholinergic neurons to generate the decisions of accepting or rejecting male courtship. [Date last reviewed: 2019-03-07]
FBgn0262647	Nup160	Nucleoporin 160kD	NA
FBgn0262656	Myc	Myc	Myc (Myc) encodes a transcription factor that is homologous to vertebrate Myc proto-oncogenes. It contributes to cell growth, cell competition and regenerative proliferation. [Date last reviewed: 2019-03-14]
FBgn0262699	fzr	fizzy-related	fizzy-related (fzr) encodes a protein that binds to the Anaphase-Promoting Complex/Cyclosome (APC/C) ubiquitin ligase to stimulate its activity during G1 phase. [Date last reviewed: 2019-03-07]
FBgn0262714	Sap130	Sin3A-associated protein 130	NA
FBgn0262716	Arp3	Actin-related protein 3	NA
FBgn0262730	dtn	detonator	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0262731	CG33941	NA	NA
FBgn0262732	mbf1	multiprotein bridging factor 1	multiprotein bridging factor 1 (mbf1) encodes a transcriptional co-activator that bridges between sequence-specific transcriptional regulators and the product of Tbp. Under stress, the product of mbf1 in the cytoplasm can translocate into the nucleus and serve as a co-activator to induce stress-reponse genes. [Date last reviewed: 2019-03-14]
FBgn0262733	Src64B	Src oncogene at 64B	Src oncogene at 64B (Src64B) encodes a Src family nonreceptor tyrosine kinase. It has many biological roles, including ring canal morphogenesis in oogenesis and the male germline, microfilament ring constriction during cellularization, and modulation of growth and apoptosis. Some of its roles overlap with those of the product of Src42A. [Date last reviewed: 2019-03-14]
FBgn0262734	eIF4H1	eukaryotic translation initiation factor 4H1	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0262736	Vha16-1	Vacuolar H[+] ATPase 16kD subunit 1	Vacuolar H[+] ATPase 16kD subunit 1 (Vha16-1) encodes the proteolipid component of V-ATPase, which is a multi-functional channel protein. It contributes to vesicle-membrane fusion, hydrophilic molecule transport and intercellular communication. [Date last reviewed: 2019-09-26]
FBgn0262737	mub	mushroom-body expressed	mushroom-body expressed (mub) encodes a protein involved in thermosensory behavior and regulation of alternative mRNA splicing. [Date last reviewed: 2019-09-26]
FBgn0262738	norpA	no receptor potential A	NA
FBgn0262739	AGO1	Argonaute-1	Argonaute-1 (AGO1) encodes an Argonaute/Piwi family protein, which interacts with microRNAs to form miRNA-induced silencing complexes (miRISCs). miRISCs are guided to target and repress mRNAs either by transcript destabilisation, translational inhibition, or both. [Date last reviewed: 2019-03-07]
FBgn0262740	Evi5	Ecotropic viral integration site 5	NA
FBgn0262743	Fs(2)Ket	Female sterile (2) Ketel	Female sterile (2) Ketel (Fs(2)Ket) encodes a protein that functions in nuclear protein import, formation of the spindle apparatus and nuclear envelope assembly. It is also involved in biogenesis of the mitochondria. [Date last reviewed: 2019-09-26]
FBgn0262782	Mdh1	Malate dehydrogenase 1	Malate dehydrogenase 1 (Mdh1) encodes a L-malate dehydrogenase involved in the interconversion of malate and oxaloacetate. [Date last reviewed: 2019-09-12]
FBgn0262794	CG43175	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-10-13]
FBgn0262801	twr	twisted bristles roughened eye	NA
FBgn0262817	CG43188	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-10-13]
FBgn0262818	CG43189	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-10-13]
FBgn0262866	S6kII	Ribosomal protein S6 kinase II	Ribosomal protein S6 kinase II (S6kII) encodes a protein that functions as a downstream effector and regulator of the MAP kinase pathway. It is involved in MAP kinase regulated developmental processes, organization of the neuromuscular junction and adult behavior including circadian rhythm and learning. [Date last reviewed: 2019-03-14]
FBgn0262870	axo	axotactin	NA
FBgn0262871	lute	lute	lute (lute) encodes a protein involved in neurogenesis. [Date last reviewed: 2019-09-19]
FBgn0262872	milt	milton	NA
FBgn0262886	lncRNA:CR43241	long non-coding RNA:CR43241	NA
FBgn0262887	lncRNA:CR43242	long non-coding RNA:CR43242	NA
FBgn0262900	CG43255	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-10-13]
FBgn0262937	Rabex-5	Rabaptin-5-associated exchange factor for Rab5	NA
FBgn0262945	lncRNA:CR43264	long non-coding RNA:CR43264	NA
FBgn0262947	lncRNA:CR43266	long non-coding RNA:CR43266	NA
FBgn0262952	mt:ND4	mitochondrial NADH-ubiquinone oxidoreductase chain 4	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0262954	Polr2K	RNA polymerase II, I and III subunit K	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0262955	Polr2B	RNA polymerase II subunit B	RNA polymerase II subunit B (Polr2B) encodes a protein thought to be present in all RNA pol II complexes. [Date last reviewed: 2019-03-14]
FBgn0262970	CR43281	NA	NA
FBgn0262975	cnc	cap-n-collar	cap-n-collar (cnc) encodes cap-n-collar (cnc) encodes a transcription factor that interacts with the product of Keap1 to regulate the activation of genes by oxidative stress. The cnc-encoded product also contributes to mRNA localization mediated by microtubules, dendrite morphogenesis and intestinal stem cell homeostasis. [Date last reviewed: 2019-03-07]
FBgn0262976	lawc	leg arista wing complex	NA
FBgn0262993	lncRNA:CR43301	long non-coding RNA:CR43301	NA
FBgn0263005	Chpf	Chondroitin polymerizing factor	NA
FBgn0263006	SERCA	Sarco/endoplasmic reticulum Ca(2+)-ATPase	Sarco/endoplasmic reticulum Ca(2+)-ATPase (SERCA) encodes an endoplasmic reticulum (ER) calcium pump with roles in ER calcium homeostasis and lipid storage. [Date last reviewed: 2019-09-26]
FBgn0263025	HSPBAP1	HSPB1 associated protein 1	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0263041	CG43336	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0263042	CG43337	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-10-13]
FBgn0263048	Gpdh3	Glycerol-3-phosphate dehydrogenase 3	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0263077	M7BP	Myosin-7a binding protein	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0263079	CG43338	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0263093	CR43361	NA	NA
FBgn0263102	psq	pipsqueak	pipsqueak (psq) encodes a transcription factor that regulates chromatin silencing. It mediates the interaction of Polycomb group (Pc-G) members with Pc-G response elements. [Date last reviewed: 2019-06-13]
FBgn0263106	DnaJ-1	DnaJ-like-1	DnaJ-like-1 (DnaJ-1) encodes a heat-shock protein co-factor that regulates and interacts with larger heat shock proteins providing client specificity. It regulates the folding of proteins whose misfolding leads to age-dependent neurodegeneration. [Date last reviewed: 2019-05-16]
FBgn0263108	BtbVII	BTB-protein-VII	NA
FBgn0263110	CG43367	NA	NA
FBgn0263111	cac	cacophony	cacophony (cac) encodes the primary structural subunit of a voltage-gated calcium channel, which is located at presynaptic active zones. It functions in evoked neurotransmitter release at neuromuscular synapses. It contributes to male courtship behavior and a wide range of neurophysiological processes. [Date last reviewed: 2019-03-07]
FBgn0263112	Mitf	Mitf	Mitf (Mitf) encodes a b-HLH-Zip transcription factor that regulates basic cellular processes in part by controlling the expression of the vacuolar (H[+])-ATPase subunits. [Date last reviewed: 2018-10-04]
FBgn0263113	Cc2d2a	Coiled-coil and C2 domain containing 2A	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0263118	tx	taxi	taxi (tx) encodes a transcription factor that affects cell adhesion by regulating the expression of mys. It is involved in the development of multiple organs and cell-types including tendon cells, chordotonal organs and the wing. [Date last reviewed: 2019-03-14]
FBgn0263120	Acsl	Acyl-CoA synthetase long-chain	NA
FBgn0263132	Cht6	Chitinase 6	Chitinase 6 (Cht6) encodes an enzyme involved in ecdysis. [Date last reviewed: 2019-07-11]
FBgn0263133	mEFG1	mitochondrial translation elongation factor G 1	mitochondrial translation elongation factor G 1 (mEFG1) encodes a mitochondrial elongation factor that catalyzes the translocation of the mRNAs and tRNAs along the ribosomes via GTP hydrolysis. [Date last reviewed: 2019-03-14]
FBgn0263143	vret	vreteno	vreteno (vret) encodes a Tudor-domain containing protein required for piRNA biogenesis. vret mutants are sterile due to transposon de-repression. [Date last reviewed: 2019-05-16]
FBgn0263144	bin3	bicoid-interacting protein 3	bicoid-interacting protein 3 (bin3) encodes an RNA methyltransferase that adds a 5'-methyl cap to the product of snRNA:7SK preventing its degradation. It contributes to inhibition of cad mRNA translation in the anterior of the embryo. [Date last reviewed: 2019-05-16]
FBgn0263197	Patronin	Patronin	Patronin (Patronin) encodes a microtubule minus-end binding protein that can promote acentrosomal nucleation of microtubules. Apical localisation of the Patronin product orients microtubules in polarised epithelial cells and in oocytes. [Date last reviewed: 2019-05-16]
FBgn0263198	Acn	Acinus	Acinus (Acn) encodes nuclear protein that, together with the products of a Bin1 and RnpS1, forms the ASAP complex that contributes to the regulation of alternative splicing. The Acn protein also functions in basal, starvation-independent autophagy. [Date last reviewed: 2019-05-16]
FBgn0263199	Galk	Galactokinase	Galactokinase (Galk) encodes a protein involved in galactose metabolism that regulates calcineurin-induced cardiac enlargement. [Date last reviewed: 2019-03-07]
FBgn0263200	Galt	Galactose-1-phosphate uridylyltransferase	Galactose-1-phosphate uridylyltransferase (Galt) encodes an enzyme that contributes to galactose homeostasis and adult locomotory behavior. [Date last reviewed: 2019-03-07]
FBgn0263220	Hk	Hyperkinetic	Hyperkinetic (Hk) encodes a beta-subunit of Sh K[+] channels and modulates its channel function. It is important in regulating action potentials in neurons and muscles, and transmitter release. [Date last reviewed: 2019-03-07]
FBgn0263231	bel	belle	belle (bel) encodes a DEAD-box RNA helicase that functions both as positive and negative translation regulator. It is essential for embryo viability and fertility, and is required for the maintenance of male germ-line stem cells. [Date last reviewed: 2019-05-16]
FBgn0263232	Nxf3	Nuclear export factor 3	NA
FBgn0263237	Cdk7	Cyclin-dependent kinase 7	Cyclin-dependent kinase 7 (Cdk7) encodes a serine/threonine protein kinase whose activity depends on the regulatory subunits encoded by CycH and Mat1. This trimeric Cdk complex activates other Cdks by phosphorylation in their T-loop and is called Cdk activating kinase (CAK). CAK can also be part of TFIIH, where the product of Cdk7 phosphorylates different transcription substrates (e.g. CTD of Pol II). [Date last reviewed: 2019-03-07]
FBgn0263240	Coop	Corepressor of Pangolin	Corepressor of Pangolin (Coop) encodes a protein that represses gene expression mediated by Wg signaling. It binds to the product of pan preventing the interaction of the products of pan with arm. By antagonizing Wg signaling, it contributes to patterning and cell fate decisions during development. [Date last reviewed: 2019-03-07]
FBgn0263241	Mocs1	Molybdenum cofactor synthesis 1	NA
FBgn0263256	CG43394	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0263257	Cngl	Cyclic nucleotide-gated ion channel-like	NA
FBgn0263258	chas	chascon	NA
FBgn0263260	sel	seele	seele (sel) encodes an endoplasmic reticulum-resident Saposin-like protein. It is involved in dorsal-ventral patterning by contributing to secretion and activation of the protease encoded by ea. [Date last reviewed: 2019-03-14]
FBgn0263278	Fic	Fic domain-containing protein	Fic domain-containing protein (Fic) encodes an enzymes that catalyzes the addition of AMP residues to proteins. The products of Fic are located in the endoplasmic reticulum (ER), where they AMPylate the main ER chaperone encoded by Hsc70-3. [Date last reviewed: 2019-03-07]
FBgn0263289	scrib	scribble	scribble (scrib) encodes a scaffolding protein that is part of the conserved machinery regulating apicobasal polarity. It acts with the products of dlg1 and l(2)gl to distinguish the basolateral domain of epithelial cells and neuroblasts, via reciprocally antagonistic interactions with the aPKC/par-6 complex that impacts vesicle trafficking. The product of scrib also organizes synaptic architecture and is implicated in learning and memory. [Date last reviewed: 2019-03-14]
FBgn0263316	Mrp4	Multidrug resistance protein 4	Multidrug resistance protein 4 (Mrp4) encodes a member of the MRP/ABCC subfamily of ATP-binding cassette (ABC) transporters. It is involved in the response to oxidative stress and hypoxia. [Date last reviewed: 2019-09-12]
FBgn0263336	lncRNA:CR43417	long non-coding RNA:CR43417	NA
FBgn0263346	smash	smallish	NA
FBgn0263351	AP-2mu	Adaptor Protein complex 2, mu subunit	Adaptor Protein complex 2, μ subunit (AP-2μ) encodes a component of the AP-2 adaptor complex, which recruits certain transmembrane proteins into clathrin-coated pits for endocytic internalization. [Date last reviewed: 2019-03-07]
FBgn0263352	Unr	Upstream of N-ras	Upstream of N-ras (Unr) encodes an RNA binding protein that functions as an RNA chaperone and translation regulator. It performs opposing, sex-specific, roles in X-chromosome dosage compensation by regulating lncRNA:roX2 RNA conformation in males and msl-2 mRNA translation in females. [Date last reviewed: 2019-03-21]
FBgn0263355	CG31688	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2017-07-13]
FBgn0263391	hts	hu li tai shao	hu li tai shao (hts) encodes an adducin homolog that is associated with the plasma membrane cytoskeleton, fusome and oocyte ring canals. It has essential functions in muscle, nerve and other tissues, and is required for fertility in males and females. [Date last reviewed: 2019-03-07]
FBgn0263392	Tet	Ten-Eleven Translocation (TET) family protein	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0263395	hppy	happyhour	happyhour (hppy) encodes the Drosophila orthologue of MAP4K3, a Ser/Thr Kinase belonging to the Germinal Center Kinase I family of Ste20-related kinases. The function of hppy has being linked to the Egfr, Hippo and Tor signalling pathways. [Date last reviewed: 2019-03-07]
FBgn0263396	sqd	squid	squid (sqd) encodes a member of the hnRNPA family of RNA binding proteins. It is involved in the localization and translational regulation of grk mRNA in oogenesis. [Date last reviewed: 2019-03-14]
FBgn0263397	Ih	I[[h]] channel	I[[h]] channel (Ih) encodes a low-threshold, voltage-gated ion channel. It may influence excitatory postsynaptic potential kinetics and integration. [Date last reviewed: 2019-09-26]
FBgn0263398	Uck	Uridine-cytidine kinase	NA
FBgn0263413	lncRNA:CR43459	long non-coding RNA:CR43459	NA
FBgn0263490	mld	molting defective	molting defective (mld) encodes a nuclear zinc finger protein required for ecdysone biosynthesis. [Date last reviewed: 2019-03-14]
FBgn0263504	lncRNA:CR43493	long non-coding RNA:CR43493	NA
FBgn0263507	lncRNA:CR43496	long non-coding RNA:CR43496	NA
FBgn0263510	nclb	no child left behind	NA
FBgn0263593	Lpin	Lipin	Lipin (Lpin) encodes a protein that plays a central role in fat body function and energy metabolism. It works as a phosphatidate phosphatase required for normal insulin pathway signaling. [Date last reviewed: 2019-03-14]
FBgn0263594	lost	lost	lost (lost) encodes a protein that interacts with the RNA-binding protein encoded by rump for posterior localization of mRNAs by diffusion/entrapment during late stages of oogenesis. The identification of the product of lost in various RNP complexes suggests a broad role in RNA metabolism. [Date last reviewed: 2019-03-14]
FBgn0263598	Vha68-2	Vacuolar H[+] ATPase 68 kDa subunit 2	Vacuolar H[+] ATPase 68 kDa subunit 2 (Vha68-2) encodes a component of the V1 subunit of the vacuolar ATPase, which acidifies endosomal compartments including the lysosome and influences the activity of several signaling pathways. [Date last reviewed: 2019-09-26]
FBgn0263599	Brr2	Brr2 U5 snRNP complex subunit	NA
FBgn0263600	PolD1	DNA polymerase delta subunit 1	NA
FBgn0263601	mib1	mind bomb 1	mind bomb 1 (mib1) encodes an E3 ubiquitin ligase that regulates Notch signaling by influencing the endocytosis of the products of Dl and Ser. [Date last reviewed: 2019-05-16]
FBgn0263602	Tasp1	Taspase 1	Taspase 1 (Tasp1) encodes a threonine-type endopeptidase involved in spermatogenesis and the defense response to Gram-negative bacteria. [Date last reviewed: 2019-09-19]
FBgn0263603	Zn72D	Zinc-finger protein at 72D	Zinc-finger protein at 72D (Zn72D) encodes a protein involved in the splicing of the mle transcript. [Date last reviewed: 2019-09-26]
FBgn0263605	l(3)72Dn	lethal (3) 72Dn	NA
FBgn0263606	Hsc20	Heat shock protein cognate 20	Heat shock protein cognate 20 (Hsc20) encodes a mitochondrial chaperone that facilitates iron sulfur cluster assembly or transfer from the product of IscU to other scaffold proteins. Hsc20 is required for larval growth and cellular iron sensing. [Date last reviewed: 2019-03-07]
FBgn0263607	l(3)72Dp	lethal (3) 72Dp	NA
FBgn0263620	asRNA:CR43629	antisense RNA:CR43629	NA
FBgn0263659	lncRNA:CR43650	long non-coding RNA:CR43650	NA
FBgn0263665	lncRNA:CR43656	long non-coding RNA:CR43656	NA
FBgn0263667	Lpt	Lost PHDs of trr	Lost PHDs of trr (Lpt) encodes a core component of COMPASS-like nuclear receptor coactivator complexes. It is involved in histone methylation and dpp/BMP signaling regulation. [Date last reviewed: 2019-09-12]
FBgn0263697	Uba3	Ubiquitin-like activating enzyme 3	NA
FBgn0263706	CG43658	NA	NA
FBgn0263738	Ada2a	transcriptional Adaptor 2a	NA
FBgn0263740	eIF2gamma	eukaryotic translation initiation factor 2 subunit gamma	NA
FBgn0263745	CR43670	NA	NA
FBgn0263746	CR43671	NA	NA
FBgn0263747	CG43672	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0263755	Su(var)3-9	Suppressor of variegation 3-9	NA
FBgn0263768	lncRNA:CR43685	long non-coding RNA:CR43685	NA
FBgn0263773	fok	fledgling of Klp38B	NA
FBgn0263782	Hmgcr	HMG Coenzyme A reductase	HMG Coenzyme A reductase (Hmgcr) encodes the rate-controlling enzyme of the mevalonate pathway that produces isoprenoids. It is required during heart tube formation, molting regulation and primordial germ cell migration. [Date last reviewed: 2019-05-16]
FBgn0263829	CG34334	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0263831	Gen	XPG-like endonuclease	XPG-like endonuclease (Gen) encodes a nuclease that cuts Holliday junctions, flaps, and replication forks during DNA and replication fork repair. [Date last reviewed: 2019-03-07]
FBgn0263832	Rcd5	Reduction in Cnn dots 5	Reduction in Cnn dots 5 (Rcd5) encodes a protein that belongs to the family of forkhead-associated domain proteins. As part of the non-specific lethal complex, it regulates transcription of housekeeping genes by facilitating recruitment of RNA polymerase II to promoters. During mitosis it plays a key role in chromosomal-dependent microtubule assembly, centriole duplication and pericentriolar material maturation. [Date last reviewed: 2019-03-14]
FBgn0263852	Dad1	Defender against apoptotic cell death 1	NA
FBgn0263855	BubR1	Bub1-related kinase	Bub1-related kinase (BubR1) encodes a motif-rich protein with a C-terminal serine-threonine kinase domain. During prometaphase and metaphase, it plays important roles in spindle assembly checkpoint signalling, stabilization of kinetochore-microtuble attachments and chromosome alignment. It is also essential to maintain sister-chromatid cohesion during meiotic progression and for normal maintenance of Synaptonemal Complex in females. [Date last reviewed: 2019-03-07]
FBgn0263863	mRpL45	mitochondrial ribosomal protein L45	NA
FBgn0263864	Dark	Death-associated APAF1-related killer	Death-associated APAF1-related killer (Dark) encodes an essential component of the apoptosome. The products of Dark and Dronc form a pivotal holoenzyme required for apoptotic cell death with the products of Dark acting as an adaptor of the multimeric complex. [Date last reviewed: 2019-03-07]
FBgn0263873	sick	sickie	sickie (sick) encodes a cytoskeletal protein that positively regulates F-actin-mediated axonal growth by relaying the non-canonical RacGTPase-Slingshot-Cofilin pathway. It also mediates immune deficiency signaling pathway, which activates the product of Rel. [Date last reviewed: 2019-03-14]
FBgn0263911	COX8	Cytochrome c oxidase subunit 8	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0263916	Ent2	Equilibrative nucleoside transporter 2	Equilibrative nucleoside transporter 2 (Ent2) encodes a member of the equilibrative nucleoside transporter family and represents a primary plasma membrane equilibrative transporter. It is involved in stress signaling and adenosin recycling. [Date last reviewed: 2019-03-07]
FBgn0263929	jvl	javelin-like	javelin-like (jvl) encodes a microtubule associated protein whose roles include actin and microtubule organization during oocyte development and bristle growth. [Date last reviewed: 2019-06-06]
FBgn0263930	dally	division abnormally delayed	division abnormally delayed (dally) encodes a core protein of heparan sulfate proteoglycans of the glypican family. It acts as a co-receptor for growth factors and morphogens, such as the products of dpp, wg, hh, upd1 and FGFs, affecting signaling and distribution of these ligands. The roles of the product of dally include wing development and germline stem cell maintenance. [Date last reviewed: 2019-03-07]
FBgn0263933	ebi	ebi	ebi (ebi) encodes a nuclear-localized protein that regulates Egfr, Notch and Wg signaling pathways. ebi encoded product contributes to multiple processes including wing growth and eye development as well as regulation of transcription and innate immune response. [Date last reviewed: 2019-03-07]
FBgn0263967	asRNA:CR43723	antisense RNA:CR43723	NA
FBgn0263968	nonC	no-on-and-no-off transient C	no-on-and-no-off transient C (nonC) encodes a phosphatidylinositol 3-kinase-related kinase. It functions in the nonsense-mediated mRNA decay (NMD) pathway by phosphorylation of the core NMD regulator encoded by Upf1. [Date last reviewed: 2019-03-14]
FBgn0263977	Tim17b	Translocase of the inner mitochondrial membrane 17b	Translocase of the inner mitochondrial membrane 17b (Tim17b) encodes a small subunit of the mitochondrial inner membrane translocase complex. It is strictly required for the delivery of proteins to the mitochondrial matrix. [Date last reviewed: 2019-03-14]
FBgn0263979	Caf1-55	Chromatin assembly factor 1, p55 subunit	Chromatin assembly factor 1, p55 subunit (Caf1-55) encodes a subunit of the MuvB core complex. The MuvB core binds to the oncoprotein encoded by Myb and the Rbf-E2f2-Dp tumor suppressor complex, thereby controlling the expression of many genes, including critical regulators of the cell cycle. [Date last reviewed: 2019-03-21]
FBgn0263987	spoon	spoonbill	NA
FBgn0263993	CG43736	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0263995	cpo	couch potato	couch potato (cpo) is most strongly expressed in nuclei of the central and peripheral nervous systems and the ring gland, where its product may regulate gene transcription to control complex neurological and neuroendocrine functions. It is required for normal synaptic transmission, climate adaptation, olfaction, diapause and behavioral responses. [Date last reviewed: 2019-03-07]
FBgn0263998	Ack-like	Activated Cdc42 kinase-like	Activated Cdc42 kinase-like (Ack-like) encodes a non-receptor tyrosine kinase that participates in signaling by the small GTPase encoded by Cdc42. It is involved in embryonic dorsal closure, an epithelial morphogenetic event. [Date last reviewed: 2019-03-07]
FBgn0264006	dysc	dyschronic	dyschronic (dysc) encodes a protein that regulates the localization of the calcium-activated potassium channel encoded by slo. The product of dysc impacts circadian locomotor patterns, synaptic morphology, active zone structure, and both spontaneous and evoked neurotransmitter release. [Date last reviewed: 2019-03-07]
FBgn0264075	tgo	tango	NA
FBgn0264078	Flo2	Flotillin 2	Flotillin 2 (Flo2) encodes encodes a scaffold protein that contributes to the anti-parasitoid immune response and the secretion and spreading of the ligands encoded by wg and hh. [Date last reviewed: 2019-03-07]
FBgn0264089	sli	slit	slit (sli) encodes a secreted glycoprotein that acts as a ligand for the Robo receptor family and co-receptors, including the products of Sdc and Dscam1. The product of sli functions as second messenger (via Abl) and receptor dependent, providing repellent (neural growth cone), attractive (trachea), and polarising (cardioblasts) cues for differentiating cells. [Date last reviewed: 2019-03-14]
FBgn0264270	Sxl	Sex lethal	Sex lethal (Sxl) encodes an RNA-binding protein, member of the RNA recognition motif (RRM) family. It is a master-feminizing switch contributing to all aspects of sexual dimorphism. [Date last reviewed: 2019-03-14]
FBgn0264291	Det	Deterin	Deterin (Det) encodes a component of the chromosomal passenger complex involved in regulation of apoptosis and cytokinesis. [Date last reviewed: 2019-07-11]
FBgn0264294	Cyt-b5	Cytochrome b5	Cytochrome b5 (Cyt-b5) encodes a microsomal cytochrome b5 which is a small hemoprotein that participates in electron transfer in multiple biochemical reactions and pathways, including the metabolism of endogenous and xenobiotic compounds. [Date last reviewed: 2021-01-21]
FBgn0264305	CG43783	NA	NA
FBgn0264307	orb2	orb2	NA
FBgn0264324	spg	sponge	sponge (spg) encodes a DOCK family RhoGEF involved in nervous system development and regulation of signaling pathways. [Date last reviewed: 2019-08-01]
FBgn0264325	Atg6	Autophagy-related 6	Autophagy-related 6 (Atg6) encodes a component of the Vps34 complex that is required for the formation of PI3P, and functions in vesicle trafficking including autophagy and endocytosis. [Date last reviewed: 2019-03-07]
FBgn0264326	PolE1	DNA polymerase epsilon subunit 1	DNA polymerase epsilon subunit 1 (PolE1) encodes the large subunit of DNA pol epsilon, an essential DNA polymerase participating with DNA pol alpha and DNA pol delta in cellular DNA replication. The C-terminal and N-terminal regions of the products of PolE1 have differential requirements in mitotic and endo-replicating cells. [Date last reviewed: 2019-09-26]
FBgn0264357	SNF4Agamma	SNF4/AMP-activated protein kinase gamma subunit	SNF4/AMP-activated protein kinase gamma subunit (SNF4Aγ) encodes a protein involved in lipid metabolism, autophagy and response to starvation. [Date last reviewed: 2019-09-26]
FBgn0264389	opm	opossum	opossum (opm) encodes a p24 protein that contributes to the secretion of Wnt ligands. [Date last reviewed: 2019-09-12]
FBgn0264437	lncRNA:CR43855	long non-coding RNA:CR43855	NA
FBgn0264439	lncRNA:CR43857	long non-coding RNA:CR43857	NA
FBgn0264449	CG43867	NA	NA
FBgn0264475	lncRNA:CR43883	long non-coding RNA:CR43883	NA
FBgn0264490	Eip93F	Ecdysone-induced protein 93F	Ecdysone-induced protein 93F (Eip93F) encodes a DNA binding protein that plays an important role as an adult determinant during fly metamorphosis. [Date last reviewed: 2019-10-03]
FBgn0264491	how	held out wings	held out wings (how) encodes an RNA-binding protein highly expressed in the mesoderm and tendon cells. It is spliced into two isoforms: how(L) and how(S). how(L) induces RNA destabilization, whereas How(S) stabilizes the RNA targets. [Date last reviewed: 2019-03-07]
FBgn0264492	CkIIalpha	casein kinase IIalpha	NA
FBgn0264493	rdx	roadkill	roadkill (rdx) encodes a protein that functions as a substrate recognition component of Cul3-based E3 ubiquitin ligase complexes. It regulates the Hedgehog signaling pathway by promoting the degradation of the transcription factor encoded by ci. [Date last reviewed: 2019-03-14]
FBgn0264494	CG17646	NA	NA
FBgn0264495	gpp	grappa	NA
FBgn0264501	lncRNA:CR43900	long non-coding RNA:CR43900	NA
FBgn0264542	hwt	heavyweight	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0264560	garz	gartenzwerg	gartenzwerg (garz) encodes a guanine nucleotide exchange factor localized to the cis-Golgi apparatus. The roles of the product of garz include membrane and protein trafficking between the Golgi apparatus and the endoplasmic reticulum. It is required for epithelial morphogenesis in the embryo. [Date last reviewed: 2019-03-07]
FBgn0264561	Glg1	Golgi complex-localized glycoprotein 1	NA
FBgn0264562	Hr4	Hormone receptor 4	Hormone receptor 4 (Hr4) encodes a nuclear receptor that acts both upstream and downstream of the steroid hormone ecdysone. In the prothoracic gland the product of Hr4 acts as a repressor of ecdysone production. In other tissues, including the salivary gland and the fat body, Hr4 is transcriptionally induced by ecdysone to transduce the effects of the hormone. [Date last reviewed: 2019-03-07]
FBgn0264602	lncRNA:CR43951	long non-coding RNA:CR43951	NA
FBgn0264607	CaMKII	Calcium/calmodulin-dependent protein kinase II	Calcium/calmodulin-dependent protein kinase II (CaMKII) encodes an abundant Ca[2+]-calmodulin-regulated serine/threonine protein kinase. In neurons it has a wide range of substrates in multiple subcellular compartments, regulating synaptic plasticity, excitability and cytoskeletal interactions. [Date last reviewed: 2019-03-07]
FBgn0264617	asRNA:CR43957	antisense RNA:CR43957	NA
FBgn0264672	Eogt	EGF-domain O-GlcNAc transferase	EGF-domain O-GlcNAc transferase (Eogt) encodes a protein that localizes to the lumen of the endoplasmic reticulum and transfers β-N-acetylglucosamine (GlcNAc) to extracelluar epidermal growth factor-like domains independently of the product of sxc. The product of Eogt mediates cell adhesion mediated by the product of dpy. [Date last reviewed: 2019-03-07]
FBgn0264678	lncRNA:CR43963	long non-coding RNA:CR43963	NA
FBgn0264691	Lst8	Lst8	Lst8 (Lst8) encodes a conserved TOR-binding protein that may be required for Crtc-dependent regulation of cell growth based on genetic evidence. [Date last reviewed: 2019-09-26]
FBgn0264693	ens	ensconsin	ensconsin (ens) encodes a microtubule associated protein required for multiple kinesin-1 functions. It contributes to microtubule motor activity, centrosome separation, nuclear positioning and skeletal muscle development. [Date last reviewed: 2019-03-07]
FBgn0264694	mgr	merry-go-round	NA
FBgn0264699	CG43968	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-10-13]
FBgn0264702	asRNA:CR43971	antisense RNA:CR43971	NA
FBgn0264707	RhoGEF3	Rho guanine nucleotide exchange factor 3	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]
FBgn0264712	CG1172	NA	Insufficient genetic data for FlyBase to solicit a summary. [Date last reviewed: 2016-06-30]