The qORAC framework



qORAC stands for Specific Flux (q) Optimisation by Robust Adaptive Control. It is a method in which a metabolic pathway may be controlled dynamically by prescribing enzyme synthesis functions. These functions are chosen in such a way that, when coupled to the dynamics of the pathway in which these enzymes play a role, guarantee that a steady state of the system achieves maximal flux per unit expended enzyme in the pathway (called specific flux).

A full description and derivation of the method will appear in a forthcoming paper. The following files are Matlab files which may be run to generate the images in that paper. Read the README before running the files.